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Conserved domains on  [gi|757798863|ref|WP_043016065|]
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MULTISPECIES: D-amino acid dehydrogenase [Citrobacter]

Protein Classification

D-amino acid dehydrogenase( domain architecture ID 11479161)

D-amino acid dehydrogenase catalyzes the oxidative deamination of D-amino acids to yield the corresponding 2-oxo acids; also able to oxidize D-amino acid analogs

EC:  1.4.99.-
Gene Ontology:  GO:0071949|GO:0016491|GO:0008718|GO:0055130
SCOP:  3000055

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK00711 PRK00711
D-amino acid dehydrogenase;
1-415 0e+00

D-amino acid dehydrogenase;


:

Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 866.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLD 80
Cdd:PRK00711   1 MRVVVLGSGVIGVTSAWYLAQAGHEVTVIDRQPGPALETSFANAGQISPGYAAPWAAPGVPLKAIKWLFQRHAPLAIRPD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  81 GTQFQLKWMWQMLRNCDTSHYMENKGRMVRLAEYSRDCLKALRASTGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDA 160
Cdd:PRK00711  81 GDPFQLRWMWQMLRNCTASRYAVNKSRMVRLAEYSRDCLKALRAETGIQYEGRQGGTLQLFRTQQQLDAAAKDIAVLEEA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 161 GVPYQLLEASRLAEVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEQIYGVQCG 240
Cdd:PRK00711 161 GVPYELLDRDELAAVEPALAGVRHKLVGGLRLPNDETGDCQLFTQRLAAMAEQLGVKFRFNTPVDGLLVEGGRITGVQTG 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 241 EEIVKADAYVMAFGSYSTAMLKGI-VDIPVYPLKGYSLTIPVAQDDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGF 319
Cdd:PRK00711 241 GGVITADAYVVALGSYSTALLKPLgVDIPVYPLKGYSLTVPITDEDRAPVSTVLDETYKIAITRFDDRIRVGGMAEIVGF 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 320 NTELLQPRRETLEMVVRDLFPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLLLNTGHGTLGWTMACGSGQLLSDILS 399
Cdd:PRK00711 321 DLRLDPARRETLEMVVRDLFPGGGDLSQATFWTGLRPMTPDGTPIVGATRYKNLWLNTGHGTLGWTMACGSGQLLADLIS 400

                        410
                 ....*....|....*.
gi 757798863 400 GRTPAIPYDDLSVARY 415
Cdd:PRK00711 401 GRKPAIDADDLSVARY 416
 
Name Accession Description Interval E-value
PRK00711 PRK00711
D-amino acid dehydrogenase;
1-415 0e+00

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 866.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLD 80
Cdd:PRK00711   1 MRVVVLGSGVIGVTSAWYLAQAGHEVTVIDRQPGPALETSFANAGQISPGYAAPWAAPGVPLKAIKWLFQRHAPLAIRPD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  81 GTQFQLKWMWQMLRNCDTSHYMENKGRMVRLAEYSRDCLKALRASTGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDA 160
Cdd:PRK00711  81 GDPFQLRWMWQMLRNCTASRYAVNKSRMVRLAEYSRDCLKALRAETGIQYEGRQGGTLQLFRTQQQLDAAAKDIAVLEEA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 161 GVPYQLLEASRLAEVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEQIYGVQCG 240
Cdd:PRK00711 161 GVPYELLDRDELAAVEPALAGVRHKLVGGLRLPNDETGDCQLFTQRLAAMAEQLGVKFRFNTPVDGLLVEGGRITGVQTG 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 241 EEIVKADAYVMAFGSYSTAMLKGI-VDIPVYPLKGYSLTIPVAQDDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGF 319
Cdd:PRK00711 241 GGVITADAYVVALGSYSTALLKPLgVDIPVYPLKGYSLTVPITDEDRAPVSTVLDETYKIAITRFDDRIRVGGMAEIVGF 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 320 NTELLQPRRETLEMVVRDLFPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLLLNTGHGTLGWTMACGSGQLLSDILS 399
Cdd:PRK00711 321 DLRLDPARRETLEMVVRDLFPGGGDLSQATFWTGLRPMTPDGTPIVGATRYKNLWLNTGHGTLGWTMACGSGQLLADLIS 400

                        410
                 ....*....|....*.
gi 757798863 400 GRTPAIPYDDLSVARY 415
Cdd:PRK00711 401 GRKPAIDADDLSVARY 416
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-414 2.14e-105

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 316.46  E-value: 2.14e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREpGPALETSAANAGQISPGYAAPWAApgvplkaikwmfqrhaplavrld 80
Cdd:COG0665    3 ADVVVIGGGIAGLSTAYHLARRGLDVTVLERG-RPGSGASGRNAGQLRPGLAALADR----------------------- 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  81 gtqfqlkwmwqmlrncdtshymenkgRMVRLAEYSRDCLKALRASTGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDA 160
Cdd:COG0665   59 --------------------------ALVRLAREALDLWRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRAL 112

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 161 GVPYQLLEASRLAEVEPALAevAHKLTGGLRLPNDETGDCQLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEQIYGVQCG 240
Cdd:COG0665  113 GLPVELLDAAELREREPGLG--SPDYAGGLYDPDDGHVDPAKLVRALARAARAAGVRIREGTPVTGLEREGGRVTGVRTE 190

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 241 EEIVKADAYVMAFGSYSTAMLKGI-VDIPVYPLKGYSLTIPVaqDDGAPVSTILDETyKIAITRF-DNRIRVGGMAEIVG 318
Cdd:COG0665  191 RGTVRADAVVLAAGAWSARLLPMLgLRLPLRPVRGYVLVTEP--LPDLPLRPVLDDT-GVYLRPTaDGRLLVGGTAEPAG 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 319 FNTELLQPRRETLEMVVRDLFPRGGHVEQATFWTGLRPMTPDGTPVVGRTR-FKNLLLNTGHGTLGWTMACGSGQLLSDI 397
Cdd:COG0665  268 FDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGLPIIGRLPgAPGLYVATGHGGHGVTLAPAAGRLLADL 347

                        410
                 ....*....|....*..
gi 757798863 398 LSGRTPAIPYDDLSVAR 414
Cdd:COG0665  348 ILGGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 2-397 1.91e-75

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 238.84  E-value: 1.91e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863    2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPALETSAANAGQISPGYaapwaapgvplkaikwmfqrhaplavrldg 81
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSGASGRNAGLIHPGL------------------------------ 50

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   82 tqfqlkwmwqmlrncdtshYMENKGRMVRLAEYSRDCLKALRASTGIEYEGRQGGTLQLFRTAQQyENATRDIAVLEDAG 161
Cdd:pfam01266  51 -------------------RYLEPSELARLALEALDLWEELEEELGIDCGFRRCGVLVLARDEEE-EALEKLLAALRRLG 110

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  162 VPYQLLEASRLAEVEPALAEVAhkltGGLRLPNDETGDCQLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEqIYGVQCGE 241
Cdd:pfam01266 111 VPAELLDAEELRELEPLLPGLR----GGLFYPDGGHVDPARLLRALARAAEALGVRIIEGTEVTGIEEEGG-VWGVVTTG 185

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  242 EIvkaDAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPVAQDD--GAPVS-TILDETYKIAITRFDNRIRVGGMAEIVG 318
Cdd:pfam01266 186 EA---DAVVNAAGAWADLLALPGLRLPVRPVRGQVLVLEPLPEAllILPVPiTVDPGRGVYLRPRADGRLLLGGTDEEDG 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  319 FNTELLQP-RRETLEMVVRDLFPRGGHVEQAtfWTGLRPMtPDGTPVVGRTRFKNLLLNTGHGTLGWTMACGSGQLLSDI 397
Cdd:pfam01266 263 FDDPTPDPeEIEELLEAARRLFPALADIERA--WAGLRPL-PDGLPIIGRPGSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
thiamin_ThiO TIGR02352
glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine ...
 17-402 3.61e-36

glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine]


Pssm-ID: 274092 [Multi-domain]  Cd Length: 337  Bit Score: 135.57  E-value: 3.61e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   17 WYLSQAGHDVTVIDREPgPALETSAANAGQISPgyaapwaapgvplkaikwmfqrHAPlavrldgtqfqlkwmWQMLRnc 96
Cdd:TIGR02352   1 WELAKRGHSVTLFDRDP-MGGGASWAAAGMLAP----------------------HAE---------------CEYAE-- 40

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   97 dtshymenkGRMVRLAEYSR----DCLKALRASTGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDAGVPYQLLEASRL 172
Cdd:TIGR02352  41 ---------DPLFDLALESLrlypEWLEALKELTGLDTGYHQCGTLVVAFDEDDVEHLRQLADLQSATGMEVEWLSGRAL 111

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  173 AEVEPALAEvahKLTGGLRLPNDETGDCQLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEQIYGVQCGEEIVKADAYVMA 252
Cdd:TIGR02352 112 RRLEPYLSG---GIRGAVFYPDDAHVDPRALLKALEKALEKLGVEIIEHTEVQHIEIRGEKVTAIVTPSGDVQADQVVLA 188

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  253 FGSYSTAMLKGivdiPVYPLKGYSL--TIPVAQDDGAPV-STILDETYKIaITRFDNRIRVGGMAEIVGFNTellQPRRE 329
Cdd:TIGR02352 189 AGAWAGELLPL----PLRPVRGQPLrlEAPAVPLLNRPLrAVVYGRRVYI-VPRRDGRLVVGATMEESGFDT---TPTLG 260

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757798863  330 TLEMVVRD---LFPRGGHVEQATFWTGLRPMTPDGTPVVGRTRF-KNLLLNTGHGTLGWTMACGSGQLLSDILSGRT 402
Cdd:TIGR02352 261 GIKELLRDaytILPALKEARLLETWAGLRPGTPDNLPYIGEHPEdRRLLIATGHYRNGILLAPATAEVIADLILGKE 337
AlaDh_PNT_C smart01002
Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the ...
 2-47 6.00e-04

Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine.


Pssm-ID: 214966 [Multi-domain]  Cd Length: 149  Bit Score: 40.18  E-value: 6.00e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 757798863     2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREP----------GPALETSAANAGQI 47
Cdd:smart01002  22 KVVVIGAGVVGLGAAATAKGLGAEVTVLDVRParlrqlesllGARFTTLYSQAELL 77
 
Name Accession Description Interval E-value
PRK00711 PRK00711
D-amino acid dehydrogenase;
1-415 0e+00

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 866.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLD 80
Cdd:PRK00711   1 MRVVVLGSGVIGVTSAWYLAQAGHEVTVIDRQPGPALETSFANAGQISPGYAAPWAAPGVPLKAIKWLFQRHAPLAIRPD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  81 GTQFQLKWMWQMLRNCDTSHYMENKGRMVRLAEYSRDCLKALRASTGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDA 160
Cdd:PRK00711  81 GDPFQLRWMWQMLRNCTASRYAVNKSRMVRLAEYSRDCLKALRAETGIQYEGRQGGTLQLFRTQQQLDAAAKDIAVLEEA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 161 GVPYQLLEASRLAEVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEQIYGVQCG 240
Cdd:PRK00711 161 GVPYELLDRDELAAVEPALAGVRHKLVGGLRLPNDETGDCQLFTQRLAAMAEQLGVKFRFNTPVDGLLVEGGRITGVQTG 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 241 EEIVKADAYVMAFGSYSTAMLKGI-VDIPVYPLKGYSLTIPVAQDDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGF 319
Cdd:PRK00711 241 GGVITADAYVVALGSYSTALLKPLgVDIPVYPLKGYSLTVPITDEDRAPVSTVLDETYKIAITRFDDRIRVGGMAEIVGF 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 320 NTELLQPRRETLEMVVRDLFPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLLLNTGHGTLGWTMACGSGQLLSDILS 399
Cdd:PRK00711 321 DLRLDPARRETLEMVVRDLFPGGGDLSQATFWTGLRPMTPDGTPIVGATRYKNLWLNTGHGTLGWTMACGSGQLLADLIS 400

                        410
                 ....*....|....*.
gi 757798863 400 GRTPAIPYDDLSVARY 415
Cdd:PRK00711 401 GRKPAIDADDLSVARY 416
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-414 2.14e-105

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 316.46  E-value: 2.14e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREpGPALETSAANAGQISPGYAAPWAApgvplkaikwmfqrhaplavrld 80
Cdd:COG0665    3 ADVVVIGGGIAGLSTAYHLARRGLDVTVLERG-RPGSGASGRNAGQLRPGLAALADR----------------------- 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  81 gtqfqlkwmwqmlrncdtshymenkgRMVRLAEYSRDCLKALRASTGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDA 160
Cdd:COG0665   59 --------------------------ALVRLAREALDLWRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRAL 112

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 161 GVPYQLLEASRLAEVEPALAevAHKLTGGLRLPNDETGDCQLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEQIYGVQCG 240
Cdd:COG0665  113 GLPVELLDAAELREREPGLG--SPDYAGGLYDPDDGHVDPAKLVRALARAARAAGVRIREGTPVTGLEREGGRVTGVRTE 190

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 241 EEIVKADAYVMAFGSYSTAMLKGI-VDIPVYPLKGYSLTIPVaqDDGAPVSTILDETyKIAITRF-DNRIRVGGMAEIVG 318
Cdd:COG0665  191 RGTVRADAVVLAAGAWSARLLPMLgLRLPLRPVRGYVLVTEP--LPDLPLRPVLDDT-GVYLRPTaDGRLLVGGTAEPAG 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 319 FNTELLQPRRETLEMVVRDLFPRGGHVEQATFWTGLRPMTPDGTPVVGRTR-FKNLLLNTGHGTLGWTMACGSGQLLSDI 397
Cdd:COG0665  268 FDRAPTPERLEALLRRLRRLFPALADAEIVRAWAGLRPMTPDGLPIIGRLPgAPGLYVATGHGGHGVTLAPAAGRLLADL 347

                        410
                 ....*....|....*..
gi 757798863 398 LSGRTPAIPYDDLSVAR 414
Cdd:COG0665  348 ILGGEPPLDLAPFSPDR 364
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 2-404 4.22e-86

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 268.82  E-value: 4.22e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDG 81
Cdd:PRK12409   3 HIAVIGAGITGVTTAYALAQRGYQVTVFDRHRYAAMETSFANGGQLSASNAEVWNHWATVLKGLKWMLRKDAPLLLNPKP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  82 TQFQLKWMWQMLRNcdTSHYMENKGRMVRLAEYSRDCLKALRASTGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDAG 161
Cdd:PRK12409  83 SWHKYSWLAEFLAH--IPNYRANTIETVRLAIAARKHLFDIAEREGIDFDLERRGILHIYHDKAGFDHAKRVNALLAEGG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 162 VPYQLLEASRLAEVEPALAEVAHkltGGLRLPNDETGDCQLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEQIY-----G 236
Cdd:PRK12409 161 LERRAVTPEEMRAIEPTLTGEYY---GGYYTPSDSTGDIHKFTTGLAAACARLGVQFRYGQEVTSIKTDGGGVVltvqpS 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 237 VQCGEEIVKADAYVMAFGSYSTAMLKGIVD-IPVYPLKGYSLTipVAQDD-----GAPVSTILDETYKIAITRF-DNRIR 309
Cdd:PRK12409 238 AEHPSRTLEFDGVVVCAGVGSRALAAMLGDrVNVYPVKGYSIT--VNLDDeasraAAPWVSLLDDSAKIVTSRLgADRFR 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 310 VGGMAEIVGFNTELLQPRRETLEMVVRDLFPrGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLLLNTGHGTLGWTMACG 389
Cdd:PRK12409 316 VAGTAEFNGYNRDIRADRIRPLVDWVRRNFP-DVSTRRVVPWAGLRPMMPNMMPRVGRGRRPGVFYNTGHGHLGWTLSAA 394

                        410
                 ....*....|....*
gi 757798863 390 SGQLLSDILSGRTPA 404
Cdd:PRK12409 395 TADLVAQVVAQKLPA 409
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 2-397 1.91e-75

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 238.84  E-value: 1.91e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863    2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPALETSAANAGQISPGYaapwaapgvplkaikwmfqrhaplavrldg 81
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSGASGRNAGLIHPGL------------------------------ 50

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   82 tqfqlkwmwqmlrncdtshYMENKGRMVRLAEYSRDCLKALRASTGIEYEGRQGGTLQLFRTAQQyENATRDIAVLEDAG 161
Cdd:pfam01266  51 -------------------RYLEPSELARLALEALDLWEELEEELGIDCGFRRCGVLVLARDEEE-EALEKLLAALRRLG 110

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  162 VPYQLLEASRLAEVEPALAEVAhkltGGLRLPNDETGDCQLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEqIYGVQCGE 241
Cdd:pfam01266 111 VPAELLDAEELRELEPLLPGLR----GGLFYPDGGHVDPARLLRALARAAEALGVRIIEGTEVTGIEEEGG-VWGVVTTG 185

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  242 EIvkaDAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPVAQDD--GAPVS-TILDETYKIAITRFDNRIRVGGMAEIVG 318
Cdd:pfam01266 186 EA---DAVVNAAGAWADLLALPGLRLPVRPVRGQVLVLEPLPEAllILPVPiTVDPGRGVYLRPRADGRLLLGGTDEEDG 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  319 FNTELLQP-RRETLEMVVRDLFPRGGHVEQAtfWTGLRPMtPDGTPVVGRTRFKNLLLNTGHGTLGWTMACGSGQLLSDI 397
Cdd:pfam01266 263 FDDPTPDPeEIEELLEAARRLFPALADIERA--WAGLRPL-PDGLPIIGRPGSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
thiamin_ThiO TIGR02352
glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine ...
 17-402 3.61e-36

glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine]


Pssm-ID: 274092 [Multi-domain]  Cd Length: 337  Bit Score: 135.57  E-value: 3.61e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   17 WYLSQAGHDVTVIDREPgPALETSAANAGQISPgyaapwaapgvplkaikwmfqrHAPlavrldgtqfqlkwmWQMLRnc 96
Cdd:TIGR02352   1 WELAKRGHSVTLFDRDP-MGGGASWAAAGMLAP----------------------HAE---------------CEYAE-- 40

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   97 dtshymenkGRMVRLAEYSR----DCLKALRASTGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDAGVPYQLLEASRL 172
Cdd:TIGR02352  41 ---------DPLFDLALESLrlypEWLEALKELTGLDTGYHQCGTLVVAFDEDDVEHLRQLADLQSATGMEVEWLSGRAL 111

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  173 AEVEPALAEvahKLTGGLRLPNDETGDCQLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEQIYGVQCGEEIVKADAYVMA 252
Cdd:TIGR02352 112 RRLEPYLSG---GIRGAVFYPDDAHVDPRALLKALEKALEKLGVEIIEHTEVQHIEIRGEKVTAIVTPSGDVQADQVVLA 188

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  253 FGSYSTAMLKGivdiPVYPLKGYSL--TIPVAQDDGAPV-STILDETYKIaITRFDNRIRVGGMAEIVGFNTellQPRRE 329
Cdd:TIGR02352 189 AGAWAGELLPL----PLRPVRGQPLrlEAPAVPLLNRPLrAVVYGRRVYI-VPRRDGRLVVGATMEESGFDT---TPTLG 260

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757798863  330 TLEMVVRD---LFPRGGHVEQATFWTGLRPMTPDGTPVVGRTRF-KNLLLNTGHGTLGWTMACGSGQLLSDILSGRT 402
Cdd:TIGR02352 261 GIKELLRDaytILPALKEARLLETWAGLRPGTPDNLPYIGEHPEdRRLLIATGHYRNGILLAPATAEVIADLILGKE 337
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
3-274 5.20e-16

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 79.42  E-value: 5.20e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   3 VVILGSGVVGVTSAWYLSQA-GHDVTVIDREPGPALETSAANAGQISPGYAAPwaaPGVpLKA-----IKWMFQRHApla 76
Cdd:COG0579    7 VVIIGAGIVGLALARELSRYeDLKVLVLEKEDDVAQESSGNNSGVIHAGLYYT---PGS-LKArlcveGNELFYELC--- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  77 vrldgTQFQLKWmwqmlRNCdtshymenkGRMVrLAeYSRDCLKALRAstgieyegrqggtlqLFRTAQQYenatrdiav 156
Cdd:COG0579   80 -----RELGIPF-----KRC---------GKLV-VA-TGEEEVAFLEK---------------LYERGKAN--------- 114

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 157 ledaGVPY-QLLEASRLAEVEPALAEVAHkltGGLRLPndETGDC--QLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEQ 233
Cdd:COG0579  115 ----GVPGlEILDREELRELEPLLSDEGV---AALYSP--STGIVdpGALTRALAENAEANGVELLLNTEVTGIEREGDG 185

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 757798863 234 iYGVQCGEEIVKADAYVMAFGSYSTAMLK--GIV-DIPVYPLKG 274
Cdd:COG0579  186 -WEVTTNGGTIRARFVINAAGLYADRLAQmaGIGkDFGIFPVKG 228
PanE COG1893
Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of ...
 1-33 7.63e-07

Ketopantoate reductase [Coenzyme transport and metabolism]; Ketopantoate reductase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 441497 [Multi-domain]  Cd Length: 305  Bit Score: 50.63  E-value: 7.63e-07
                         10        20        30
                 ....*....|....*....|....*....|...
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREP 33
Cdd:COG1893    1 MKIAILGAGAIGGLLGARLARAGHDVTLVARGA 33
trkA PRK09496
Trk system potassium transporter TrkA;
1-33 1.90e-06

Trk system potassium transporter TrkA;


Pssm-ID: 236541 [Multi-domain]  Cd Length: 453  Bit Score: 49.74  E-value: 1.90e-06
                         10        20        30
                 ....*....|....*....|....*....|...
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREP 33
Cdd:PRK09496   1 MKIIIVGAGQVGYTLAENLSGENNDVTVIDTDE 33
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-252 7.96e-06

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 47.93  E-value: 7.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVidrepgpaLEtSAANAGqispGYAAPW--AAPGVPL------------KAIK 66
Cdd:COG3349    4 PRVVVVGGGLAGLAAAVELAEAGFRVTL--------LE-ARPRLG----GRARSFpdPDTGLPIdngqhvllgcyrNTLD 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  67 WM--------FQRHAPLAVRL-DGTQFQLK--------WMWQMLRNCdtshymenkgRMVRLAEYsrdcLKALRASTGIE 129
Cdd:COG3349   71 LLrrigaadnLVGPEPLQFPLpGGRRWTLRaprlpaplHLLRALLRA----------PGLSLADR----LALLRLLTACR 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 130 yegrqggtlqlFRTAQQYENAT-RDiaVLEDAGVPYQLLEasRLAEV----------EPALAEVAHK-----LTGG---- 189
Cdd:COG3349  137 -----------ERRWRELDDISvAD--WLRRHGQSPRLIR--RLWEPlllaalntppEQASARLALTvlretLLAGpaas 201

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757798863 190 -LRLPNDETGDcqLFTQRLALMAEQAGVKFRFNTPVDKLLSDGEQIYGVQCG-EEIVKADAYVMA 252
Cdd:COG3349  202 dLLVPRGPLSE--LFVDPALAYLEARGGEVRLGTRVRALEFDGGRVTGLVLAdGETVPADAVVLA 264
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-36 9.04e-06

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 47.24  E-value: 9.04e-06
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPA 36
Cdd:COG0654    4 TDVLIVGGGPAGLALALALARAGIRVTVVERAPPPR 39
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 1-33 1.18e-05

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 47.52  E-value: 1.18e-05
                         10        20        30
                 ....*....|....*....|....*....|...
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREP 33
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASD 34
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
5-63 1.35e-05

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 42.52  E-value: 1.35e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 757798863    5 ILGSGVVGVTSAWYLSQAGHDVTVIDREPGPAletsaanagqispGYAAPWAAPGVPLK 63
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLG-------------GNAYSYRVPGYVFD 46
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 2-35 1.39e-05

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 47.42  E-value: 1.39e-05
                         10        20        30
                 ....*....|....*....|....*....|....
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGP 35
Cdd:PRK12814 195 KVAIIGAGPAGLTAAYYLLRKGHDVTIFDANEQA 228
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 148-257 2.15e-05

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 46.36  E-value: 2.15e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 148 ENATRDIAVLEDAGVPYQLLEASRLAEVEPALAEVAHkltgglrLPNDETGdcQLFTQRLALMAEQAGVKFRFNTPVDKL 227
Cdd:COG1053   90 EEAPEAIDWLEAQGVPFSRTPDGRLPQFGGHSVGRTC-------YAGDGTG--HALLATLYQAALRLGVEIFTETEVLDL 160

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 757798863 228 LSDGEQIYGVQC-----GEEIVKADAYVMAFGSYS 257
Cdd:COG1053  161 IVDDGRVVGVVArdrtgEIVRIRAKAVVLATGGFG 195
ApbA pfam02558
Ketopantoate reductase PanE/ApbA; This is a family of 2-dehydropantoate 2-reductases also ...
 3-33 3.95e-05

Ketopantoate reductase PanE/ApbA; This is a family of 2-dehydropantoate 2-reductases also known as ketopantoate reductases, EC:1.1.1.169. The reaction catalyzed by this enzyme is: (R)-pantoate + NADP(+) <=> 2-dehydropantoate + NADPH. AbpA catalyzes the NADPH reduction of ketopantoic acid to pantoic acid in the alternative pyrimidine biosynthetic (APB) pathway. ApbA and PanE are allelic. ApbA, the ketopantoate reductase enzyme is required for the synthesis of thiamine via the APB biosynthetic pathway.


Pssm-ID: 426831 [Multi-domain]  Cd Length: 147  Bit Score: 43.37  E-value: 3.95e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 757798863    3 VVILGSGVVGVTSAWYLSQAGHDVTVIDREP 33
Cdd:pfam02558   1 IAILGAGAIGSLLGARLAKAGHDVTLILRGA 31
PRK06522 PRK06522
2-dehydropantoate 2-reductase; Reviewed
 1-36 5.29e-05

2-dehydropantoate 2-reductase; Reviewed


Pssm-ID: 235821 [Multi-domain]  Cd Length: 304  Bit Score: 44.84  E-value: 5.29e-05
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPA 36
Cdd:PRK06522   1 MKIAILGAGAIGGLFGAALAQAGHDVTLVARRGAHL 36
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 2-44 5.88e-05

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 41.42  E-value: 5.88e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 757798863    2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDR--EPGPALETSAANA 44
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLGSKVTVVERrdRLLPGFDPEIAKI 45
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
1-232 8.99e-05

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 44.43  E-value: 8.99e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHD--VTVIDREPGPALETSAANAGQISPG--YAapwaaPGvPLKAikwmfqrhapla 76
Cdd:PRK11728   3 YDFVIIGGGIVGLSTAMQLQERYPGarIAVLEKESGPARHQTGHNSGVIHAGvyYT-----PG-SLKA------------ 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  77 vrldgtqfqlkwmwqmlRNCdtshyMENKGRMVRL-AEYS---RDCLKALRASTGIEYEGRQGgtlqLFRTAQQyeNatr 152
Cdd:PRK11728  65 -----------------RFC-----RRGNEATKAFcDQHGipyEECGKLLVATSELELERMEA----LYERARA--N--- 113

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863 153 diavledaGVPYQLLEASRLAEVEPALAEVahkltGGLRLPndETG--DCQLFTQRLALMAEQAGVKFRFNTPVDKLLSD 230
Cdd:PRK11728 114 --------GIEVERLDAEELREREPNIRGL-----GAIFVP--STGivDYRAVAEAMAELIQARGGEIRLGAEVTALDEH 178


                 ..
gi 757798863 231 GE 232
Cdd:PRK11728 179 AN 180
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 2-33 9.63e-05

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 44.38  E-value: 9.63e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREP 33
Cdd:PRK12810 145 KVAVVGSGPAGLAAADQLARAGHKVTVFERAD 176
PRK07588 PRK07588
FAD-binding domain;
1-33 1.29e-04

FAD-binding domain;


Pssm-ID: 169028 [Multi-domain]  Cd Length: 391  Bit Score: 43.96  E-value: 1.29e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREP 33
Cdd:PRK07588   1 MKVAISGAGIAGPTLAYWLRRYGHEPTLIERAP 33
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
1-35 1.40e-04

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 43.95  E-value: 1.40e-04
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAgHDVTVIDREPGP 35
Cdd:COG2907    4 MRIAVIGSGISGLTAAWLLSRR-HDVTLFEANDRL 37
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 2-33 1.51e-04

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 43.97  E-value: 1.51e-04
                         10        20        30
                 ....*....|....*....|....*....|..
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREP 33
Cdd:COG0493  123 KVAVVGSGPAGLAAAYQLARAGHEVTVFEALD 154
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
3-35 1.75e-04

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 43.74  E-value: 1.75e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 757798863   3 VVILGSGVVGVTSAWYLSQAGHDVTVIDREPGP 35
Cdd:PRK06183  13 VVIVGAGPVGLTLANLLGQYGVRVLVLERWPTL 45
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 2-35 2.11e-04

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 42.88  E-value: 2.11e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGP 35
Cdd:COG0446  126 RAVVIGGGPIGLELAEALRKRGLKVTLVERAPRL 159
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 1-33 4.23e-04

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 41.98  E-value: 4.23e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREP 33
Cdd:COG0569   96 MHVIIIGAGRVGRSLARELEEEGHDVVVIDKDP 128
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 1-254 5.06e-04

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 41.92  E-value: 5.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863    1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPALetsaanaGQISPgYAAPWAAPGVPLKAIKWmfqrhAPLAVRLD 80
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEDEGTCPY-------GGCVL-SKALLGAAEAPEIASLW-----ADLYKRKE 67

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863   81 GTQFQLKWMWQMLRNCDTSHYMENKGRMVrlaeysrdcLKALRASTGIEYEGRQ-----GGTLQLFRTAQQYENATRDIA 155
Cdd:pfam07992  68 EVVKKLNNGIEVLLGTEVVSIDPGAKKVV---------LEELVDGDGETITYDRlviatGARPRLPPIPGVELNVGFLVR 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757798863  156 VLEDAGVPYQLLEASRLA---------EVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLALMAEQAGVKFRFNTPVDK 226
Cdd:pfam07992 139 TLDSAEALRLKLLPKRVVvvgggyigvELAAALAKLGKEVTLIEALDRLLRAFDEEISAALEKALEKNGVEVRLGTSVKE 218

                         250       260
                  ....*....|....*....|....*....
gi 757798863  227 LLSDGEqIYGVQCGEE-IVKADAYVMAFG 254
Cdd:pfam07992 219 IIGDGD-GVEVILKDGtEIDADLVVVAIG 246
PRK05868 PRK05868
FAD-binding protein;
2-35 5.57e-04

FAD-binding protein;


Pssm-ID: 180297 [Multi-domain]  Cd Length: 372  Bit Score: 41.90  E-value: 5.57e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGP 35
Cdd:PRK05868   3 TVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGL 36
AlaDh_PNT_C smart01002
Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the ...
 2-47 6.00e-04

Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine.


Pssm-ID: 214966 [Multi-domain]  Cd Length: 149  Bit Score: 40.18  E-value: 6.00e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 757798863     2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREP----------GPALETSAANAGQI 47
Cdd:smart01002  22 KVVVIGAGVVGLGAAATAKGLGAEVTVLDVRParlrqlesllGARFTTLYSQAELL 77
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 2-49 8.53e-04

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 41.76  E-value: 8.53e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPALETSAANAGQISP 49
Cdd:PRK01747 262 DAAIIGGGIAGAALALALARRGWQVTLYEADEAPAQGASGNRQGALYP 309
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-36 8.76e-04

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 41.39  E-value: 8.76e-04
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPA 36
Cdd:COG2072    7 VDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVG 42
PRK07233 PRK07233
hypothetical protein; Provisional
 2-33 9.07e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 41.41  E-value: 9.07e-04
                         10        20        30
                 ....*....|....*....|....*....|..
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREP 33
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAKRGHEVTVFEADD 32
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
1-33 1.01e-03

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 41.27  E-value: 1.01e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQ---AGHDVTVIDREP 33
Cdd:COG1252    2 KRIVIVGGGFAGLEAARRLRKklgGDAEVTLIDPNP 37
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
2-31 1.30e-03

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 41.06  E-value: 1.30e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVI---DR 31
Cdd:COG1231    9 DVVIVGAGLAGLAAARELRKAGLDVTVLearDR 41
MurD COG0771
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ...
 1-64 1.65e-03

UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440534 [Multi-domain]  Cd Length: 445  Bit Score: 40.45  E-value: 1.65e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGPALETSAANAGQIS----PGYAAPWAA-------PGVPLKA 64
Cdd:COG0771    5 KKVLVLGLGKSGLAAARLLAKLGAEVTVSDDRPAPELAAAELEAPGVEvvlgEHPEELLDGadlvvksPGIPPDH 79
PRK06753 PRK06753
hypothetical protein; Provisional
 1-45 1.65e-03

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 40.44  E-value: 1.65e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREPgpalETSAANAG 45
Cdd:PRK06753   1 MKIAIIGAGIGGLTAAALLQEQGHEVKVFEKNE----SVKEVGAG 41
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 2-35 1.88e-03

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 40.63  E-value: 1.88e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGP 35
Cdd:PRK12771 139 RVAVIGGGPAGLSAAYHLRRMGHAVTIFEAGPKL 172
PRK10015 PRK10015
oxidoreductase; Provisional
 211-257 2.06e-03

oxidoreductase; Provisional


Pssm-ID: 182194 [Multi-domain]  Cd Length: 429  Bit Score: 40.35  E-value: 2.06e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 757798863 211 AEQAGVKFRFNTPVDKLLSDGEQIYGVQCGEEIVKADAYVMAFGSYS 257
Cdd:PRK10015 118 AEQAGAQFIPGVRVDALVREGNKVTGVQAGDDILEANVVILADGVNS 164
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
2-35 2.80e-03

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 39.74  E-value: 2.80e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGP 35
Cdd:COG1251  144 RVVVIGGGLIGLEAAAALRKRGLEVTVVERAPRL 177
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-35 3.52e-03

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 39.45  E-value: 3.52e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGP 35
Cdd:COG1233    4 YDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTP 38
UDPG_MGDP_dh_N pfam03721
UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose ...
 1-30 4.26e-03

UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 397677 [Multi-domain]  Cd Length: 186  Bit Score: 38.00  E-value: 4.26e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 757798863    1 MRVVILGSGVVGVTSAWYLSQAGHDVTVID 30
Cdd:pfam03721   1 MKISVIGLGYVGLPTAACLAEIGHDVIGVD 30
PRK12770 PRK12770
putative glutamate synthase subunit beta; Provisional
 2-35 4.85e-03

putative glutamate synthase subunit beta; Provisional


Pssm-ID: 237197 [Multi-domain]  Cd Length: 352  Bit Score: 38.82  E-value: 4.85e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 757798863   2 RVVILGSGVVGVTSAWYLSQAGHDVTVIDREPGP 35
Cdd:PRK12770  20 KVAIIGAGPAGLAAAGYLACLGYEVHVYDKLPEP 53
PRK12921 PRK12921
oxidoreductase;
1-32 6.54e-03

oxidoreductase;


Pssm-ID: 183829 [Multi-domain]  Cd Length: 305  Bit Score: 38.30  E-value: 6.54e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVIDRE 32
Cdd:PRK12921   1 MRIAVVGAGAVGGTFGGRLLEAGRDVTFLVRP 32
PRK07208 PRK07208
hypothetical protein; Provisional
 3-33 6.79e-03

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 38.72  E-value: 6.79e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 757798863   3 VVILGSGVVGVTSAWYLSQAGHDVTVIDREP 33
Cdd:PRK07208   7 VVIIGAGPAGLTAAYELLKRGYPVTVLEADP 37
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 1-33 7.25e-03

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 38.68  E-value: 7.25e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAG--HDVTVIDREP 33
Cdd:PRK11883   1 KKVAIIGGGITGLSAAYRLHKKGpdADITLLEASD 35
Ugd COG1004
UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];
1-30 9.76e-03

UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440628 [Multi-domain]  Cd Length: 436  Bit Score: 38.08  E-value: 9.76e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 757798863   1 MRVVILGSGVVGVTSAWYLSQAGHDVTVID 30
Cdd:COG1004    1 MKIAVIGTGYVGLVTAACLAELGHEVTCVD 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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