|
Name |
Accession |
Description |
Interval |
E-value |
| F420_G6P_family |
TIGR03557 |
F420-dependent oxidoreductase, G6PDH family; Members of this protein family include ... |
4-319 |
1.72e-170 |
|
F420-dependent oxidoreductase, G6PDH family; Members of this protein family include F420-dependent glucose-6-phosphate dehydrogenases (TIGR03554) and related proteins. All members of this family come from species that synthesize coenzyme F420, with the exception of those that belong to TIGR03885, a clade within this family in which cofactor binding may instead be directed to FMN. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 274645 Cd Length: 316 Bit Score: 475.72 E-value: 1.72e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 4 VGYTLMCEQAGPKELVDHAVRAEAAGFDHLVMSDHYYPWLESQGHSPYAWSVLGAVAHATSRAELMSFVTCPIRRYHPAV 83
Cdd:TIGR03557 1 IGYFLMCEQSGPRELVRQAVAAEQAGFDFLWISDHFHPWLDEQGHSPFVWSVLGALAQATERLPLTTAVTCPTMRYHPAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 84 VAQKASTIGVLSDGRFTLGLGAGENLNEHVVG-GWPHVQQRHEMFEEALQIIRPLLNGETLTFSGNHFDVPDAYVWDRPD 162
Cdd:TIGR03557 81 VAQAAATSAVLSDGRFTLGLGSGENLNEHVVGdGWPSVDVRLEMLREAVEIIRELWQGGYVDHRGKHYTVDSARLYDLPE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 163 RPVPMAVAASGRQSATLAAEYADAMIATDPLSHLIDMYEEAGGAGRPRYGQVAICYGPDEDECRKIVHDQFRWFGLGWKV 242
Cdd:TIGR03557 161 EPPPIGVSAFGPRAVRLAARIGDGLIATEPDADLVEAFREAGGGGKPVQGQVPVCWDPDEDAAVKTAHRQFRWFALGWKV 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 759607353 243 NADLPGPESFEAATRFVREEDVAEGISCGPDTDRHVEAFKKFVEAGFTHVALVQVGGDtQPMFLDWAQEELLPRLRE 319
Cdd:TIGR03557 241 NQELPTPAHFAAATQLVREEDVAASIPCGPDPDRHVEAVREYVDAGFDEVALVQIGPD-QDGFFDFYATELLPALRE 316
|
|
| SsuD |
COG2141 |
Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase ... |
25-319 |
3.41e-54 |
|
Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase) [Coenzyme transport and metabolism, General function prediction only]; Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase) is part of the Pathway/BioSystem: Pyrimidine degradation
Pssm-ID: 441744 [Multi-domain] Cd Length: 301 Bit Score: 178.97 E-value: 3.41e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 25 AEAAGFDHLVMSDHYYPWlesQGHSPYAWSVLGAVAHATSRAELMSFVTCPIRRyHPAVVAQKASTIGVLSDGRFTLGLG 104
Cdd:COG2141 1 AERLGFDRVWVADHHFPP---GGASPDPWVLLAALAAATSRIRLGTGVVVLPLR-HPLVVAEQFATLDHLSGGRLDLGVG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 105 AGENLNEHVVGGWPHvQQRHEMFEEALQIIRPLLNGETLTFSGNHFDVPDAYVWDRP--DRPVPMAVAASGRQSATLAAE 182
Cdd:COG2141 77 RGWGPDEFAAFGLDH-DERYERFEEALEVLRRLWTGEPVTFEGEFFTVEGARLVPRPvqGPHPPIWIAGSSPAGARLAAR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 183 YADAMIAT----DPLSHLIDMYEEAGG-AGR-----PRYGQVAICYGPDEDECRKIVHDQFRWFglgwkvnADLP-GPES 251
Cdd:COG2141 156 LGDGVFTAggtpEELAEAIAAYREAAAaAGRdpddlRVSVGLHVIVAETDEEARERARPYLRAL-------LALPrGRPP 228
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 759607353 252 FEAATRFVREEDVAEGISCG--PDTDRHVEAFKKFVE-AGFTHVALVQVGGDTQPM--FLDWAQEELLPRLRE 319
Cdd:COG2141 229 EEAEEGLTVREDLLELLGAAlvGTPEQVAERLEELAEaAGVDEFLLQFPGLDPEDRlrSLELFAEEVLPLLRR 301
|
|
| Bac_luciferase |
pfam00296 |
Luciferase-like monooxygenase; |
11-291 |
1.13e-49 |
|
Luciferase-like monooxygenase;
Pssm-ID: 425589 [Multi-domain] Cd Length: 313 Bit Score: 167.54 E-value: 1.13e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 11 EQAGPKELVDHAVRAEAAGFDHLVMSDHYYPWlesqgHSPYAWSVLGAVAHATSRAELMSFVTcPIRRYHPAVVAQKAST 90
Cdd:pfam00296 18 GSESLRYLVELARAAEELGFDGVWLAEHHGGP-----GGPDPFVVLAALAAATSRIRLGTAVV-PLPTRHPAVLAEQAAT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 91 IGVLSDGRFTLGLGAGENLNEHVVGGWPHvQQRHEMFEEALQIIRPLLNGETLTFSGNHFDVPDAYVWDRPDRPVPMAVA 170
Cdd:pfam00296 92 LDHLSGGRFDLGLGTGGPAVEFRRFGVDH-DERYARLREFLEVLRRLWRGEPVDFEGEFFTLDGAFLLPRPVQGIPVWVA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 171 ASGRQSATLAAEYADAMIAT-----DPLSHLID----MYEEAG-GAGRPRYG-QVAICYGPDEDECRKIVHDQFRWFGLG 239
Cdd:pfam00296 171 ASSPAMLELAARHADGLLLWgfappAAAAELIErvraGAAEAGrDPADIRVGaSLTVIVADTEEEARAEARALIAGLPFY 250
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 759607353 240 WKVNA------------DLPGPESFEAATRFVREEDVAEGISCGPDtDRHVEAFKKFVEAGFTH 291
Cdd:pfam00296 251 RMDSEgagrlaeareigEEYDAGDWAGAADAVPDELVRAFALVGTP-EQVAERLAAYAEAGVDH 313
|
|
| PRK02271 |
PRK02271 |
methylenetetrahydromethanopterin reductase; Provisional |
15-185 |
1.23e-18 |
|
methylenetetrahydromethanopterin reductase; Provisional
Pssm-ID: 235022 [Multi-domain] Cd Length: 325 Bit Score: 84.61 E-value: 1.23e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 15 PKELVDHAVRAEAAGFDHLVMSDHYypwlesQGHSPYAwsVLGAVAHATSRAELMSFVTCPIRRyHPAVVAQKASTIGVL 94
Cdd:PRK02271 13 VKKIAYLAKLAEDNGFDYAWITDHY------NNRDVYM--TLAAIAAATDTIKLGPGVTNPYTR-HPAITASAIATLDEI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 95 SDGRFTLGLGAG-----ENLNEHVVGGWPHVqqrhemfEEALQIIRPLLNGETLTFSGNhFDVPDAYVWDRPD-RPVPMA 168
Cdd:PRK02271 84 SGGRAVLGIGPGdkatlDALGIEWEKPLRTV-------KEAIEVIRKLWAGERVEHDGT-FKAAGAKLNVKPVqGEIPIY 155
|
170
....*....|....*..
gi 759607353 169 VAASGRQSATLAAEYAD 185
Cdd:PRK02271 156 MGAQGPKMLELAGEIAD 172
|
|
| Alkanesulfonate_monoxygenase |
cd01094 |
Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the ... |
18-231 |
6.86e-16 |
|
Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin mononucleotide (FMNH2), which is provided by the NADPH-dependent FMN oxidoreductase (SsuE).
Pssm-ID: 238527 [Multi-domain] Cd Length: 244 Bit Score: 75.77 E-value: 6.86e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 18 LVDHAVRAEAAGFDhlvmsdhyYPWLESQGHSPYAWSVLGAVAHATSRAELMS-FVTCPIrryHPAVVAQKASTIGVLSD 96
Cdd:cd01094 30 NRQIAQAAEELGFD--------GALSPTGSSGPDGWTVAAALAAATERLKFLVaIRPGLI---APTVAARQAATLDHISG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 97 GRFTLGLGAGENLNEH-VVGGWPHVQQRHEMFEEALQIIRPLLNGET-LTFSGNHFDVPDAYVWDRP--DRPVPMAVAAS 172
Cdd:cd01094 99 GRLGLNVVTGGDPAELrMDGDFLDHDERYARADEFLEVLRRLWTSDEpFDFEGKFYRFKNAFLRPKPpqQPHPPIYFGGS 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 759607353 173 GRQSATLAAEYADA-MIATDPLS----HLIDMYEEAGGAGR-PRYGQVA-ICYGPDEDECRKIVHD 231
Cdd:cd01094 179 SEAAIEFAARHADVyFTWGEPPAqvaeAIARVRAAAAAAGRdVRFGIRLhVIVRDTEEEAWAYADR 244
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| F420_G6P_family |
TIGR03557 |
F420-dependent oxidoreductase, G6PDH family; Members of this protein family include ... |
4-319 |
1.72e-170 |
|
F420-dependent oxidoreductase, G6PDH family; Members of this protein family include F420-dependent glucose-6-phosphate dehydrogenases (TIGR03554) and related proteins. All members of this family come from species that synthesize coenzyme F420, with the exception of those that belong to TIGR03885, a clade within this family in which cofactor binding may instead be directed to FMN. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 274645 Cd Length: 316 Bit Score: 475.72 E-value: 1.72e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 4 VGYTLMCEQAGPKELVDHAVRAEAAGFDHLVMSDHYYPWLESQGHSPYAWSVLGAVAHATSRAELMSFVTCPIRRYHPAV 83
Cdd:TIGR03557 1 IGYFLMCEQSGPRELVRQAVAAEQAGFDFLWISDHFHPWLDEQGHSPFVWSVLGALAQATERLPLTTAVTCPTMRYHPAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 84 VAQKASTIGVLSDGRFTLGLGAGENLNEHVVG-GWPHVQQRHEMFEEALQIIRPLLNGETLTFSGNHFDVPDAYVWDRPD 162
Cdd:TIGR03557 81 VAQAAATSAVLSDGRFTLGLGSGENLNEHVVGdGWPSVDVRLEMLREAVEIIRELWQGGYVDHRGKHYTVDSARLYDLPE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 163 RPVPMAVAASGRQSATLAAEYADAMIATDPLSHLIDMYEEAGGAGRPRYGQVAICYGPDEDECRKIVHDQFRWFGLGWKV 242
Cdd:TIGR03557 161 EPPPIGVSAFGPRAVRLAARIGDGLIATEPDADLVEAFREAGGGGKPVQGQVPVCWDPDEDAAVKTAHRQFRWFALGWKV 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 759607353 243 NADLPGPESFEAATRFVREEDVAEGISCGPDTDRHVEAFKKFVEAGFTHVALVQVGGDtQPMFLDWAQEELLPRLRE 319
Cdd:TIGR03557 241 NQELPTPAHFAAATQLVREEDVAASIPCGPDPDRHVEAVREYVDAGFDEVALVQIGPD-QDGFFDFYATELLPALRE 316
|
|
| flavin_revert |
TIGR03885 |
probable non-F420 flavinoid oxidoreductase; This model represents a clade of proteins within ... |
4-317 |
1.68e-89 |
|
probable non-F420 flavinoid oxidoreductase; This model represents a clade of proteins within the larger subfamily TIGR03557. The parent model includes the F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554) and many other proteins. Excepting the members of this family, all members of TIGR03557 occur in species capable of synthesizing coenzyme F420. All members of the seed alignment for this model are from species that lack F420 biosynthesis. It is suggested that members of this family bind FMN, or FO, or a novel flavinoid cofactor, but not F420 per se. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 274834 Cd Length: 315 Bit Score: 270.03 E-value: 1.68e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 4 VGYTLMCEQAGPKELVDHAVRAEAAGFDHLVMSDHYYPWLESQGHSPYAWSVLGAVAHATSraelMSF--VTCPIRRYHP 81
Cdd:TIGR03885 1 IGYHASHEQFAPSDLLQYVQAAEQAGFDAVMSSDHFHPWSERQGQSGFAWSWLGAALQATS----LPFgiVTAPGQRYHP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 82 AVVAQKASTIGVLSDGRFTLGLGAGENLNEHVVGG-WPHVQQRHEMFEEALQIIRPLLNGETLTFSGnHFDVPDAYVWDR 160
Cdd:TIGR03885 77 AILAQAAATLAEMFPGRFWIALGSGEALNEHITGDaWPAKAERNARLRECAEIIRALLRGETVTHRG-LVTVEEARLYSL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 161 PDRPVPMAVAASGRQSATLAAEYADAMIAT----DPLSHLIDMYEEAGGAGRPRYGQVAICYGPDEDECRKIVHDQFRWF 236
Cdd:TIGR03885 156 PETPPPLIGAALTVETARWAGAWADGLITVnqppEKLQEIVEAFREGGGAGKPVYLQVQLSYAPTEEEALAAAHEQWRNN 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 237 GLGWKVNADLPGPESFEAATRFVREEDVAEGISCGPDTDRHVEAFKKFVEAGFTHVALVQVGGDtQPMFLDWAQEELLPR 316
Cdd:TIGR03885 236 VLPPEVLWDLRRPEDFDAAARSVRPEDVDEHVRISDDLGQHAEWIQELADLGFDEIYLHNVGRD-QERFIDDFGEHVLPA 314
|
.
gi 759607353 317 L 317
Cdd:TIGR03885 315 L 315
|
|
| SsuD |
COG2141 |
Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase ... |
25-319 |
3.41e-54 |
|
Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase) [Coenzyme transport and metabolism, General function prediction only]; Flavin-dependent oxidoreductase, luciferase family (includes alkanesulfonate monooxygenase SsuD and methylene tetrahydromethanopterin reductase) is part of the Pathway/BioSystem: Pyrimidine degradation
Pssm-ID: 441744 [Multi-domain] Cd Length: 301 Bit Score: 178.97 E-value: 3.41e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 25 AEAAGFDHLVMSDHYYPWlesQGHSPYAWSVLGAVAHATSRAELMSFVTCPIRRyHPAVVAQKASTIGVLSDGRFTLGLG 104
Cdd:COG2141 1 AERLGFDRVWVADHHFPP---GGASPDPWVLLAALAAATSRIRLGTGVVVLPLR-HPLVVAEQFATLDHLSGGRLDLGVG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 105 AGENLNEHVVGGWPHvQQRHEMFEEALQIIRPLLNGETLTFSGNHFDVPDAYVWDRP--DRPVPMAVAASGRQSATLAAE 182
Cdd:COG2141 77 RGWGPDEFAAFGLDH-DERYERFEEALEVLRRLWTGEPVTFEGEFFTVEGARLVPRPvqGPHPPIWIAGSSPAGARLAAR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 183 YADAMIAT----DPLSHLIDMYEEAGG-AGR-----PRYGQVAICYGPDEDECRKIVHDQFRWFglgwkvnADLP-GPES 251
Cdd:COG2141 156 LGDGVFTAggtpEELAEAIAAYREAAAaAGRdpddlRVSVGLHVIVAETDEEARERARPYLRAL-------LALPrGRPP 228
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 759607353 252 FEAATRFVREEDVAEGISCG--PDTDRHVEAFKKFVE-AGFTHVALVQVGGDTQPM--FLDWAQEELLPRLRE 319
Cdd:COG2141 229 EEAEEGLTVREDLLELLGAAlvGTPEQVAERLEELAEaAGVDEFLLQFPGLDPEDRlrSLELFAEEVLPLLRR 301
|
|
| ArgArg_F420 |
TIGR04465 |
TAT-translocated F420-dependent dehydrogenase, FGD2 family; Members of this family are ... |
4-318 |
7.60e-50 |
|
TAT-translocated F420-dependent dehydrogenase, FGD2 family; Members of this family are F420-binding enzymes with a proven functional N-terminal twin-arginine translocation (TAT) signal. Members are homologous to the cytosolic F420-dependent glucose-6-phosphate dehydrogenase but do not share the same function.
Pssm-ID: 275258 Cd Length: 364 Bit Score: 169.72 E-value: 7.60e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 4 VGYTLMCEQAGPKELVDHAVRAEAAGFDHLVMSDHYYPWLESQGHSPYAWSVLGAVAHATSRAELMSFVTCPIRRYHPAV 83
Cdd:TIGR04465 48 VGFVLSHEQFRTDRLVAQAQAAEQAGFRYVWASDHIQPWQDNEGHSMFPWLTLALVGNSTSHVSFGTGVTCPTYRYHPAT 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 84 VAQKASTIGVLSDGRFTLGLGAGENLNEH-VVGGWPHVQQRHEMFEEALQIIRPLLNGETLTFSGNHFDVPDAYVWDRPD 162
Cdd:TIGR04465 128 VAQAFASLAILNPGRVFLGVGTGERLNEQaATNQFGNYRERHDRLIEAIQLIRQLWSGQRISFSGRYFQTNSLKLYDVPA 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 163 RPVPMAVAASGRQSATLAAEYADAMIA-----TDPlsHLIDMYEE-AGGAGR--PRYGQVAICYGPDEDEcRKIVHDQFR 234
Cdd:TIGR04465 208 TPPPIFVAAGGPKSATLAGQYGDGWITqardvTNP--KLLAAFAAgAQAAGRdpATLGKRAELFAVVGDD-AEAARAATL 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 235 WFGLGWKVnaDLPGPESFEAATRFVREEDVAEGISCGPDTDRHVEAFKKFVEAGftHVALVQVGGDTQPMFLDWAQEELL 314
Cdd:TIGR04465 285 WRFTAGAV--DQPNPVEIQRAAESNPIDKVLAGWTVGTDPAVHIGAVQAVLDAG--AVPFLHFPQDDPVTAIEFYRTNVL 360
|
....
gi 759607353 315 PRLR 318
Cdd:TIGR04465 361 PELH 364
|
|
| Bac_luciferase |
pfam00296 |
Luciferase-like monooxygenase; |
11-291 |
1.13e-49 |
|
Luciferase-like monooxygenase;
Pssm-ID: 425589 [Multi-domain] Cd Length: 313 Bit Score: 167.54 E-value: 1.13e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 11 EQAGPKELVDHAVRAEAAGFDHLVMSDHYYPWlesqgHSPYAWSVLGAVAHATSRAELMSFVTcPIRRYHPAVVAQKAST 90
Cdd:pfam00296 18 GSESLRYLVELARAAEELGFDGVWLAEHHGGP-----GGPDPFVVLAALAAATSRIRLGTAVV-PLPTRHPAVLAEQAAT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 91 IGVLSDGRFTLGLGAGENLNEHVVGGWPHvQQRHEMFEEALQIIRPLLNGETLTFSGNHFDVPDAYVWDRPDRPVPMAVA 170
Cdd:pfam00296 92 LDHLSGGRFDLGLGTGGPAVEFRRFGVDH-DERYARLREFLEVLRRLWRGEPVDFEGEFFTLDGAFLLPRPVQGIPVWVA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 171 ASGRQSATLAAEYADAMIAT-----DPLSHLID----MYEEAG-GAGRPRYG-QVAICYGPDEDECRKIVHDQFRWFGLG 239
Cdd:pfam00296 171 ASSPAMLELAARHADGLLLWgfappAAAAELIErvraGAAEAGrDPADIRVGaSLTVIVADTEEEARAEARALIAGLPFY 250
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 759607353 240 WKVNA------------DLPGPESFEAATRFVREEDVAEGISCGPDtDRHVEAFKKFVEAGFTH 291
Cdd:pfam00296 251 RMDSEgagrlaeareigEEYDAGDWAGAADAVPDELVRAFALVGTP-EQVAERLAAYAEAGVDH 313
|
|
| F420_Rv1855c |
TIGR03560 |
probable F420-dependent oxidoreductase, Rv1855c family; Coenzyme F420 has a limited ... |
22-210 |
4.70e-36 |
|
probable F420-dependent oxidoreductase, Rv1855c family; Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes one such subfamily, exemplified by Rv1855c from Mycobacterium tuberculosis. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 274648 [Multi-domain] Cd Length: 227 Bit Score: 129.74 E-value: 4.70e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 22 AVRAEAAGFDHLVMSDHYY---PWLESQGHSPYAWSVLGAVAHATSRAELMSFVTCPIRRyHPAVVAQKASTIGVLSDGR 98
Cdd:TIGR03560 19 ARAAEDAGFDALFRSDHFLqmpMVGPPEGPTLEAWTTLAGLARETSRIRLGTLVTGVTYR-HPGLLAKMVATVDVLSGGR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 99 FTLGLGAGENLNEHVVGG--WPHVQQRHEMFEEALQIIRPLLNGETLTFSGNHFDVPDAYVWDRPDRP--VPMAVAASG- 173
Cdd:TIGR03560 98 AELGLGAGWYEREHRAYGipFPPLAERFERLEEALQIITGMWSGEGVTFDGRHYRLADAIALPKPLQRphPPILIGGGGe 177
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 759607353 174 RQSATLAAEYADA--MIATDP--LSHLID-MYEEAGGAGRPR 210
Cdd:TIGR03560 178 KRTLRLAARYADEfnLVFGPPdeLAHKFEvLRAHCEAAGRDP 219
|
|
| F420_MSMEG_2516 |
TIGR03621 |
probable F420-dependent oxidoreductase, MSMEG_2516 family; Coenzyme F420 is produced by ... |
10-206 |
9.43e-26 |
|
probable F420-dependent oxidoreductase, MSMEG_2516 family; Coenzyme F420 is produced by methanogenic archaea, a number of the Actinomycetes (including Mycobacterium tuberculosis), and rare members of other lineages. The resulting information-rich phylogenetic profile identifies candidate F420-dependent oxidoreductases within the family of luciferase-like enzymes (pfam00296), where the species range for the subfamily encompasses many F420-positive genomes without straying beyond. This family is uncharacterized, and named for member MSMEG_2516 from Mycobacterium smegmatis. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 200301 [Multi-domain] Cd Length: 295 Bit Score: 103.99 E-value: 9.43e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 10 CEQAGPKE-LVDHAVRAEAAGFDHLVMSDHyypwLESQghSPYAwsVLGAVAHATSRAELMSFV-TCPIrrYHPAVVAQK 87
Cdd:TIGR03621 7 LEGPESARdLVDLARRAEDAGFDVLTVPDH----LGAP--APFA--ALTAAAAATTTLRLGTLVlNNDF--RHPALLARE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 88 ASTIGVLSDGRFTLGLGAGENLNEHVVGG--WPHVQQRHEMFEEALQIIRPLLNGETLTFSGNHfDVPDAyvwdRPDRPV 165
Cdd:TIGR03621 77 AATLDALSDGRLELGLGAGYVRSEFDAAGipFDSPGVRVDRLEETLTYLRRLLADEPVTFPGHH-GTPRP----RQGPRP 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 759607353 166 PMAVAASGRQSATLAAEYAD----------------AMIATDPLSHLIDMYEEAGGA 206
Cdd:TIGR03621 152 PLLIGGNGDRLLRLAARHADivglagasanpdagllTHATADPLAERVAFVREAAGD 208
|
|
| PRK02271 |
PRK02271 |
methylenetetrahydromethanopterin reductase; Provisional |
15-185 |
1.23e-18 |
|
methylenetetrahydromethanopterin reductase; Provisional
Pssm-ID: 235022 [Multi-domain] Cd Length: 325 Bit Score: 84.61 E-value: 1.23e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 15 PKELVDHAVRAEAAGFDHLVMSDHYypwlesQGHSPYAwsVLGAVAHATSRAELMSFVTCPIRRyHPAVVAQKASTIGVL 94
Cdd:PRK02271 13 VKKIAYLAKLAEDNGFDYAWITDHY------NNRDVYM--TLAAIAAATDTIKLGPGVTNPYTR-HPAITASAIATLDEI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 95 SDGRFTLGLGAG-----ENLNEHVVGGWPHVqqrhemfEEALQIIRPLLNGETLTFSGNhFDVPDAYVWDRPD-RPVPMA 168
Cdd:PRK02271 84 SGGRAVLGIGPGdkatlDALGIEWEKPLRTV-------KEAIEVIRKLWAGERVEHDGT-FKAAGAKLNVKPVqGEIPIY 155
|
170
....*....|....*..
gi 759607353 169 VAASGRQSATLAAEYAD 185
Cdd:PRK02271 156 MGAQGPKMLELAGEIAD 172
|
|
| F420_MSMEG_4879 |
TIGR03564 |
F420-dependent oxidoreductase, MSMEG_4879 family; Coenzyme F420 is produced by methanogenic ... |
18-294 |
2.50e-18 |
|
F420-dependent oxidoreductase, MSMEG_4879 family; Coenzyme F420 is produced by methanogenic archaea, a number of the Actinomycetes (including Mycobacterium tuberculosis), and rare members of other lineages. The resulting information-rich phylogenetic profile identifies candidate F420-dependent oxidoreductases within the family of luciferase-like enzymes (pfam00296), where the species range for the subfamily encompasses many F420-positive genomes without straying beyond. This family is uncharacterized, and named for member MSMEG_4879 from Mycobacterium smegmatis. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 274651 Cd Length: 265 Bit Score: 82.79 E-value: 2.50e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 18 LVDHAVRAEAAGFDHLvmsdhyypWLeSQGHSPYAWSVLGAVAHATSRAELMSFVTcPIRRYHPAVVAQKASTIGVLSDG 97
Cdd:TIGR03564 1 LVADARRAAAAGLDSA--------WL-GQVYGYDALTALALVGRAVPGIELGTAVV-PTYPRHPLALASQALTAQAAAHG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 98 RFTLGLGAGENLNEHVVGGWP-HVQQRHemFEEALQIIRPLLNGETLTFSGNHFDVPDAYVWDRP-DRPVPMAVAASGRQ 175
Cdd:TIGR03564 71 RLTLGLGLSHRWIVEDMFGLPfDRPARR--LREYLTVLRPLLAGGAVDFHGETVTAHLPTSVRVPgATPVPVLVAALGPQ 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 176 SATLAAEYADAMIA--TDPL---SHLID-MYEEAGGAGRPRYGQVA---ICYGPDEDECRKIVHDQFRWFglgwkvnADL 246
Cdd:TIGR03564 149 MLRVAGELADGTVLwlAGPRtigDHIVPtITAAAEAAGRPAPRIVAgvpVAVTDDPDEARARAAAQLAFY-------ETL 221
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 759607353 247 PgpeSFEAATRFVREEDVAEGISCGpDTDRHVEAFKKFVEAGFTHVAL 294
Cdd:TIGR03564 222 P---SYRAVLDREGAENAADLAIIG-DEDAVARQLRRYADAGATDVVA 265
|
|
| Alkanesulfonate_monoxygenase |
cd01094 |
Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the ... |
18-231 |
6.86e-16 |
|
Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin mononucleotide (FMNH2), which is provided by the NADPH-dependent FMN oxidoreductase (SsuE).
Pssm-ID: 238527 [Multi-domain] Cd Length: 244 Bit Score: 75.77 E-value: 6.86e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 18 LVDHAVRAEAAGFDhlvmsdhyYPWLESQGHSPYAWSVLGAVAHATSRAELMS-FVTCPIrryHPAVVAQKASTIGVLSD 96
Cdd:cd01094 30 NRQIAQAAEELGFD--------GALSPTGSSGPDGWTVAAALAAATERLKFLVaIRPGLI---APTVAARQAATLDHISG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 97 GRFTLGLGAGENLNEH-VVGGWPHVQQRHEMFEEALQIIRPLLNGET-LTFSGNHFDVPDAYVWDRP--DRPVPMAVAAS 172
Cdd:cd01094 99 GRLGLNVVTGGDPAELrMDGDFLDHDERYARADEFLEVLRRLWTSDEpFDFEGKFYRFKNAFLRPKPpqQPHPPIYFGGS 178
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 759607353 173 GRQSATLAAEYADA-MIATDPLS----HLIDMYEEAGGAGR-PRYGQVA-ICYGPDEDECRKIVHD 231
Cdd:cd01094 179 SEAAIEFAARHADVyFTWGEPPAqvaeAIARVRAAAAAAGRdVRFGIRLhVIVRDTEEEAWAYADR 244
|
|
| F420_MSMEG_2249 |
TIGR03857 |
probable F420-dependent oxidoreductase, MSMEG_2249 family; Coenzyme F420 has a limited ... |
6-188 |
3.40e-15 |
|
probable F420-dependent oxidoreductase, MSMEG_2249 family; Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes a distinctive subfamily, found only in F420-biosynthesizing members of the Actinobacteria of the bacterial luciferase-like monooxygenase (LLM) superfamily. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 213874 Cd Length: 329 Bit Score: 74.84 E-value: 3.40e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 6 YTLMCEQAGPKELVDHAVRAEAAGFDHLvmsdhyypWLESQGHSPYAWSVLGAVAHATSRAELMSFVTCPIRRyHPAVVA 85
Cdd:TIGR03857 4 YVLPGRGADPAQAIDEARAAERLGFGTV--------YLSERWNLKEAGVVAGAIGAVTSRVRIATGITHPATR-HPLHLA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 86 QKASTIGVLSDGRFTLGLGAGenlnehVVGGWPHV---QQRHEMFEEALQIIRPLLNGETLTFSGNHFDVPDAYVWDRPD 162
Cdd:TIGR03857 75 SLAATAHALSGGRFTLGLGRG------VGAMWRAVglpTATNAALVDYADVMRRLWRGEAVRYDGPAGNYRVLRLGDLPE 148
|
170 180
....*....|....*....|....*..
gi 759607353 163 RPVP-MAVAASGRQSATLAAEYADAMI 188
Cdd:TIGR03857 149 DPAPpLVFGAIGPKGLALAGRAFDGVI 175
|
|
| Tetrahydromethanopterin_reductase |
cd01097 |
N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5, ... |
5-230 |
1.22e-13 |
|
N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420.
Pssm-ID: 238530 [Multi-domain] Cd Length: 202 Bit Score: 68.58 E-value: 1.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 5 GYTLMCEQAGPKELVDHAVRAEAAGFDhlvmsdhyypwlesqghspYAWSvlgavahatsraelmsfvtcpirryhpavv 84
Cdd:cd01097 4 GIFLSPEQPGPRELVELARAAEEAGFD-------------------SVWV------------------------------ 34
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 85 aqkasTIGVLSDGRFTLGLGAGENLNEHVVGG--WPHVQQRHEMFEEALQIIRPLLNGETLTFsGNHFDVPDAYVWDRPD 162
Cdd:cd01097 35 -----SLDALSGGRFILGLGAGGPEVEEGWGGpwFKPPARRREELEAIRRLRALRRGDPVGED-GRFLGTRSAALPPPPR 108
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 759607353 163 RPVPMAVAASGRQSATLAAEYADAMIATDPLSHLI-DMYEEAGGAGRPRyGQVaicYGPDEDECRKIVH 230
Cdd:cd01097 109 GEIPIYIGALGPKMLELAGEIADGWLPVAAPPELYeAALPAVREGAAAA-GRV---VGDPDDVAEALRR 173
|
|
| PRK00719 |
PRK00719 |
alkanesulfonate monooxygenase; Provisional |
52-185 |
1.00e-05 |
|
alkanesulfonate monooxygenase; Provisional
Pssm-ID: 234821 [Multi-domain] Cd Length: 378 Bit Score: 46.49 E-value: 1.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 52 AWSVLGAVAHATSRAE--------LMSfvtcpirryhPAVVAQKASTIGVLSDGRFTLGLgagenlnehVVGGWP----- 118
Cdd:PRK00719 56 AWLVAASLIPVTQRLKflvalrpgLMS----------PTVAARMAATLDRLSNGRLLINL---------VTGGDPaelag 116
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 759607353 119 ------HvQQRHEMFEEALQIIRPLLNGETLTFSGNHFDVPDAYVWDRP---DRPvPMAVAASGRQSATLAAEYAD 185
Cdd:PRK00719 117 dglfldH-DERYEASAEFLRIWRRLLEGETVDFEGKHIQVKGAKLLFPPvqqPYP-PLYFGGSSDAAQELAAEQVD 190
|
|
| Alkanal_monooxygenase |
cd01096 |
Alkanal monooxygenase are flavin monoxygenases. Molecular oxygen is activated by reaction with ... |
76-188 |
2.49e-04 |
|
Alkanal monooxygenase are flavin monoxygenases. Molecular oxygen is activated by reaction with reduced flavin mononucleotide (FMNH2) and reacts with an aldehyde to yield the carboxylic acid, oxidized flavin (FMN) and a blue-green light. Bacterial luciferases are heterodimers made of alpha and beta subunits which are homologous. The single activer center is on the alpha subunit. The alpha subunit has a stretch of 30 amino acid residues that is not present in the beta subunit. The beta subunit does not contain the active site and is required for the formation of the fully active heterodimer. The beta subunit does not contribute anything directly to the active site. Its role is probably to stabilize the high quantum yield conformation of the alpha subunit through interactionbs across the subunit interface.
Pssm-ID: 238529 [Multi-domain] Cd Length: 315 Bit Score: 41.98 E-value: 2.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 759607353 76 IRRYHPAVVAQKASTIGVLSDGRFTLGLGAGENLNEHVVGGWPHVQQRhEMFEEALQIIRPLLNGETLTFSGNHFDVPD- 154
Cdd:cd01096 78 ITTHHPVRIAEEALLLDQMSKGRFILGFSDCLYDKDMRFFGRPMESQR-QLFEACYEIINDALTTGYCHPDNDFYNFPKi 156
|
90 100 110
....*....|....*....|....*....|....*....
gi 759607353 155 -----AYVWDRPdrpvPMAVAASGRQSATLAAEYADAMI 188
Cdd:cd01096 157 svnphAYSKGGP----PQYVTAESAETVEWAAKKGLPLV 191
|
|
| |
