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Conserved domains on  [gi|760126027|ref|WP_043807502|]
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AAA family ATPase [Desulfatibacillum aliphaticivorans]

Protein Classification

AAA family ATPase( domain architecture ID 11428957)

AAA family ATPase containing an AAA (ATPases Associated with various cellular Activities) domain, may function as an ATP-dependent endonuclease or the ATPase component of an ABC-type transporter

CATH:  3.40.50.300
Gene Ontology:  GO:0005524|GO:0016887
PubMed:  15037234|18208389|17897320|18466635|16072036|11916378|15037233
SCOP:  2000039

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
4-134 5.77e-08

Predicted kinase, contains AAA domain [General function prediction only];


:

Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 49.91  E-value: 5.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027   4 VYILLGPKGSGKSHVGRLMESRLGIPFLLTEDIFLQFQKQGLE----TQDVYKAGFVETAKTIERLLKTKYALAFESTGA 79
Cdd:COG0645    1 LILVCGLPGSGKSTLARALAERLGAVRLRSDVVRKRLFGAGLAplerSPEATARTYARLLALARELLAAGRSVILDATFL 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 760126027  80 SPLFFELLESL--RLQFDVKLIAVSASAKVCLTRIRSRDAGVHmpADDALIEKVHRI 134
Cdd:COG0645   81 RRAQREAFRALaeEAGAPFVLIWLDAPEEVLRERLEARNAEGG--DSDATWEVLERQ 135
 
Name Accession Description Interval E-value
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
4-134 5.77e-08

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 49.91  E-value: 5.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027   4 VYILLGPKGSGKSHVGRLMESRLGIPFLLTEDIFLQFQKQGLE----TQDVYKAGFVETAKTIERLLKTKYALAFESTGA 79
Cdd:COG0645    1 LILVCGLPGSGKSTLARALAERLGAVRLRSDVVRKRLFGAGLAplerSPEATARTYARLLALARELLAAGRSVILDATFL 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 760126027  80 SPLFFELLESL--RLQFDVKLIAVSASAKVCLTRIRSRDAGVHmpADDALIEKVHRI 134
Cdd:COG0645   81 RRAQREAFRALaeEAGAPFVLIWLDAPEEVLRERLEARNAEGG--DSDATWEVLERQ 135
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 6-31 1.24e-03

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 37.54  E-value: 1.24e-03
                         10        20
                 ....*....|....*....|....*.
gi 760126027   6 ILLGPKGSGKSHVGRLMESRLGIPFL 31
Cdd:cd00464    3 VLIGMMGAGKTTVGRLLAKALGLPFV 28
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 9-163 1.71e-03

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 37.40  E-value: 1.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027    9 GPKGSGKSHVGRLMESRLGIPFLLTEDIFLQF-QKQGLETQDVYKagFVETAKTIERLLKTKyalAFE-STGASPLffeL 86
Cdd:TIGR02173   7 GPPGSGKTTVAKILAEKLSLKLISAGDIFRELaAKMGLDLIEFLN--YAEENPEIDKKIDRR---IHEiALKEKNV---V 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027   87 LES------LRLQFDVKlIAVSASAKVCLTRIRSRDagvHMPADDALIEKVHRISS---------GLALD----YDLIIR 147
Cdd:TIGR02173  79 LESrlagwiVREYADVK-IWLKAPLEVRARRIAKRE---GKSLTVARSETIEREESekrrylkfyGIDIDdlsiYDLVIN 154

                         170
                  ....*....|....*.
gi 760126027  148 NENLRESEIVELLQSV 163
Cdd:TIGR02173 155 TSNWDPNNVDIILDAL 170
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 4-130 2.94e-03

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 36.52  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027    4 VYILLGPKGSGKSHVGRLMESRLGIPFLLTEDIFLQFQKQGLETQDVYKAGFVET----AKTIERLLKTKYALAFESTGA 79
Cdd:pfam13671   1 LILLVGLPGSGKSTLARRLLEELGAVRLSSDDERKRLFGEGRPSISYYTDATDRTyerlHELARIALRAGRPVILDATNL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 760126027   80 SP----LFFELLEslRLQFDVKLIAVSASAKVCLTRI--RSRDAGVHMPADDALIEK 130
Cdd:pfam13671  81 RRderaRLLALAR--EYGVPVRIVVFEAPEEVLRERLaaRARAGGDPSDVPEEVLDR 135
aroL PRK03731
shikimate kinase AroL;
1-39 9.35e-03

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 35.30  E-value: 9.35e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 760126027   1 MKTVYILLGPKGSGKSHVGRLMESRLGIPFLLTeDIFLQ 39
Cdd:PRK03731   1 MTQPLFLVGARGCGKTTVGMALAQALGYRFVDT-DQWLQ 38
 
Name Accession Description Interval E-value
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
4-134 5.77e-08

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 49.91  E-value: 5.77e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027   4 VYILLGPKGSGKSHVGRLMESRLGIPFLLTEDIFLQFQKQGLE----TQDVYKAGFVETAKTIERLLKTKYALAFESTGA 79
Cdd:COG0645    1 LILVCGLPGSGKSTLARALAERLGAVRLRSDVVRKRLFGAGLAplerSPEATARTYARLLALARELLAAGRSVILDATFL 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 760126027  80 SPLFFELLESL--RLQFDVKLIAVSASAKVCLTRIRSRDAGVHmpADDALIEKVHRI 134
Cdd:COG0645   81 RRAQREAFRALaeEAGAPFVLIWLDAPEEVLRERLEARNAEGG--DSDATWEVLERQ 135
COG4185 COG4185
Predicted ABC-type ATPase or kinase [General function prediction only];
1-115 2.65e-06

Predicted ABC-type ATPase or kinase [General function prediction only];


Pssm-ID: 443339  Cd Length: 197  Bit Score: 45.65  E-value: 2.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027   1 MKTVYILLGPKGSGKSHVGR--LMESRLGIPFLLTEDIFLQFQKQGLETQDvYKAGfVETAKTIERLLKTKYALAFESTG 78
Cdd:COG4185    3 MPRLYIIAGPNGAGKSTFARtiLPEELGGLEFVNADLIARGLSPFNPETAA-YEAG-RLALERREELLAAGRSFAFETTL 80

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 760126027  79 ASPLFFELLESLR-LQFDVKLIAVS-ASAKVCLTRIRSR 115
Cdd:COG4185   81 SGPSKLDLIREAKaAGYRVRLIFVGlDSPELAIARVAQR 119
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 6-116 1.98e-04

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 40.11  E-value: 1.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027   6 ILLGPKGSGKSHVGRLMESRLGIPFLLTeDIFLQfQKQGLETQDVYK----AGF--VETaKTIERLLKTKYA-LAfesTG 78
Cdd:COG0703    2 VLIGMMGAGKSTVGRLLAKRLGLPFVDT-DAEIE-ERAGMSIPEIFAeegeAGFreLER-EVLAELLEEENAvIA---TG 75

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 760126027  79 AS-PLFFELLESLRLQFDVklIAVSASAKVCLTRIRSRD 116
Cdd:COG0703   76 GGaVLSPENRELLKEHGTV--VYLDASPETLLERLRRDD 112
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 6-31 1.24e-03

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 37.54  E-value: 1.24e-03
                         10        20
                 ....*....|....*....|....*.
gi 760126027   6 ILLGPKGSGKSHVGRLMESRLGIPFL 31
Cdd:cd00464    3 VLIGMMGAGKTTVGRLLAKALGLPFV 28
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 9-163 1.71e-03

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 37.40  E-value: 1.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027    9 GPKGSGKSHVGRLMESRLGIPFLLTEDIFLQF-QKQGLETQDVYKagFVETAKTIERLLKTKyalAFE-STGASPLffeL 86
Cdd:TIGR02173   7 GPPGSGKTTVAKILAEKLSLKLISAGDIFRELaAKMGLDLIEFLN--YAEENPEIDKKIDRR---IHEiALKEKNV---V 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027   87 LES------LRLQFDVKlIAVSASAKVCLTRIRSRDagvHMPADDALIEKVHRISS---------GLALD----YDLIIR 147
Cdd:TIGR02173  79 LESrlagwiVREYADVK-IWLKAPLEVRARRIAKRE---GKSLTVARSETIEREESekrrylkfyGIDIDdlsiYDLVIN 154

                         170
                  ....*....|....*.
gi 760126027  148 NENLRESEIVELLQSV 163
Cdd:TIGR02173 155 TSNWDPNNVDIILDAL 170
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 3-31 2.28e-03

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 37.03  E-value: 2.28e-03
                         10        20
                 ....*....|....*....|....*....
gi 760126027   3 TVYILLGPKGSGKSHVGRLMESRLGIPFL 31
Cdd:COG3265    2 MVIVVMGVSGSGKSTVGQALAERLGWPFI 30
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 4-130 2.94e-03

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 36.52  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027    4 VYILLGPKGSGKSHVGRLMESRLGIPFLLTEDIFLQFQKQGLETQDVYKAGFVET----AKTIERLLKTKYALAFESTGA 79
Cdd:pfam13671   1 LILLVGLPGSGKSTLARRLLEELGAVRLSSDDERKRLFGEGRPSISYYTDATDRTyerlHELARIALRAGRPVILDATNL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 760126027   80 SP----LFFELLEslRLQFDVKLIAVSASAKVCLTRI--RSRDAGVHMPADDALIEK 130
Cdd:pfam13671  81 RRderaRLLALAR--EYGVPVRIVVFEAPEEVLRERLaaRARAGGDPSDVPEEVLDR 135
Zeta_toxin pfam06414
Zeta toxin; This family consists of several bacterial zeta toxin proteins. Zeta toxin is ...
 2-150 3.39e-03

Zeta toxin; This family consists of several bacterial zeta toxin proteins. Zeta toxin is thought to be part of a postregulational killing system in bacteria. It relies on antitoxin/toxin systems that secure stable inheritance of low and medium copy number plasmids during cell division and kill cells that have lost the plasmid.


Pssm-ID: 428926  Cd Length: 192  Bit Score: 36.57  E-value: 3.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027    2 KTVYILLGPKGSGKSHVGRL----MESRLGiPFLLTEDIFLQF--QKQGLETQDVYKAGFVE-------TAKTIERLLKT 68
Cdd:pfam06414  11 PKAILLGGQPGAGKTELARAlldeLGRQGN-VVRIDPDDFRELhpHYRELQAADPKTASEYTqpdasrwVEKLLQHAIEN 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 760126027   69 KYALAFESTGASPLFFE-LLESLRLQ-FDVKLIAVSASAKVCLTRIRSR-----DAG------VHMPADDALIEKVHRIS 135
Cdd:pfam06414  90 GYNIILEGTLRSPDVAKkIARALKAAgYRVEVAAVAAPPELSWLGVLDRyeeevAEGryvpkeHHDEAFNGLRESLRALE 169

                         170
                  ....*....|....*
gi 760126027  136 SGLALDYDLIIRNEN 150
Cdd:pfam06414 170 RRKLLDRVRIKDRDG 184
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 4-31 5.40e-03

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 35.69  E-value: 5.40e-03
                         10        20
                 ....*....|....*....|....*...
gi 760126027   4 VYILLGPKGSGKSHVGRLMESRLGIPFL 31
Cdd:cd02021    1 IIVVMGVSGSGKSTVGKALAERLGAPFI 28
aroL PRK03731
shikimate kinase AroL;
1-39 9.35e-03

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 35.30  E-value: 9.35e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 760126027   1 MKTVYILLGPKGSGKSHVGRLMESRLGIPFLLTeDIFLQ 39
Cdd:PRK03731   1 MTQPLFLVGARGCGKTTVGMALAQALGYRFVDT-DQWLQ 38
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 6-37 9.38e-03

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 35.49  E-value: 9.38e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 760126027   6 ILLGPKGSGKSHVGRLMESRLGIPFLLTEDIF 37
Cdd:COG0563    4 ILLGPPGAGKGTQAKRLAEKYGIPHISTGDML 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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