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Conserved domains on  [gi|765309964|ref|WP_044637396|]
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TonB-dependent receptor [Siansivirga zeaxanthinifaciens]

Protein Classification

TonB-dependent receptor( domain architecture ID 11446927)

TonB dependent receptor having a carboxypeptidase regulatory-like domain, may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0009279|GO:0055085
PubMed:  36944260|35464957
TCDB:  1.B.14

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
103-842 2.12e-46

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


:

Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 176.56  E-value: 2.12e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 103 LEEVVIIGTGVIDLAegRETPVAVSTIKGKDIQLKSAGNVefGEALKNTPSVYVSNQAGGfgDSQIFLRGFDQVNT--AY 180
Cdd:COG1629    1 LEEVVVTATRTDESL--QDVPGSVSVISREQLEDQPATDL--GDLLRRVPGVSVTSAGGG--AGQISIRGFGGGGNrvLV 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 181 LLNGQPINGMEDGNMYWSnwSGMSDVANAVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGGNDSYSKGTLS 260
Cdd:COG1629   75 LVDGVPLNDPSGGDGGLS--YIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSYGTYRASLS 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 261 YDSGLKESGWAFSVLVDHWQAFRKYSegtAGQGQNYLFSVGYKPSETHSFNFLLTGAPQWHDQNFSDELESYERYGEKYN 340
Cdd:COG1629  153 LSGGNGKLAYRLSASYRDSDGYRDNS---DSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDD 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 341 GNSGFLEGERFTERRNYYhkpvANLNWDYnINENLELSTVLYASwgrgggtgnvgngrvvnssnglidfdqiviNNINTA 420
Cdd:COG1629  230 GTNPYSNDTDDNTRDRYS----LSLEYEH-LGDGLKLSASAYYR------------------------------YDDTDL 274

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 421 DANGNGSFSNSYLRRSSVNAHNWYGLLSNLNYEAGENWSFNLgvdgrtyngihfrqlenKLGLNGYRDNFRTDRPSTyvi 500
Cdd:COG1629  275 DSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFGGKHTL-----------------LVGLDYQRQDLDGSGYPL--- 334

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 501 tetfkaNPWSALFDYADDDQRYDYNYEEviqyIGAFGQAEYK-MDNFSafIQTAISTQSYQREGFFTGRGNGLGKSEKlS 579
Cdd:COG1629  335 ------DLGSGSLPTLTSGADDDGTTTS----LALYAQDTYKlTDKLT--LTAGLRYDYVSYDVDDTVTGTDSASGSR-S 401

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 580 KEGYNLKGGLAYKINEQHTFFGNAGIYSRQPFLDNVFADIRYDNRLASPAVDNEEIIGFEGGYR--FKNDVFRLNIDIYN 657
Cdd:COG1629  402 YSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPYSVGNPDLKPETSTNYELGLRyrLLDGRLSLSLALFY 481

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 658 TEWGNRFLNINGPriaPNNDTSTYRLTDVTQVHRGLEFDFEYRPlASNFSLRGYgslgnwkydgetpYTLQNNETGDFit 737
Cdd:COG1629  482 SDVDNEILSVPLP---NDSGFSTYYTNAGKARSYGVELELSYQL-TPGLSLNAS-------------YSYTDAKFDDD-- 542

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 738 TNGKVSLTNVKVGNAPQTSFGIGLKGNLLENLSVDFDYNiYTDLYEFVDPADVAeealagrtyesiRLPAYTLADTGITY 817
Cdd:COG1629  543 TDGSADLDGNRLPGVPPLTANLGLTYEFPGGWSLGLGVR-YVGDRYLDDANTQG------------APGGYTLVDLGAGY 609

                        730       740
                 ....*....|....*....|....*
gi 765309964 818 VFNlgdNKLTFRGNVFNLFNTAYIN 842
Cdd:COG1629  610 RFG---DNLTLSLGVDNLFDKKYAT 631
OMP_RagA_SusC super family cl37378
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 25-172 6.48e-25

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


The actual alignment was detected with superfamily member TIGR04056:

Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 111.53  E-value: 6.48e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964   25 TITGTITDAElNSPLPGANILEKGTTNGVSSDFDGNFTLETkKPNGQIVISFVGYQSITLKFSGNTSLgNIKLELDN-SL 103
Cdd:TIGR04056   2 TVTGVVVDET-GEPLIGASVVVKGTTNGTITDIDGNFSLKV-PPGAVLVFSYIGYKTQEVKVKGQKNL-NITLKEDTqEL 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 765309964  104 EEVVIIGTGV---IDLAEgretpvAVSTIKGKDIQLKSAGNveFGEALK-NTPSVYVSNQAGGFG-DSQIFLRG 172
Cdd:TIGR04056  79 DEVVVVGYGTqkkKSLTG------AVSTVKAKELKKVPVSN--LSNALQgKVAGVIITQSSGEPGgDAEIWIRG 144
 
Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
103-842 2.12e-46

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 176.56  E-value: 2.12e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 103 LEEVVIIGTGVIDLAegRETPVAVSTIKGKDIQLKSAGNVefGEALKNTPSVYVSNQAGGfgDSQIFLRGFDQVNT--AY 180
Cdd:COG1629    1 LEEVVVTATRTDESL--QDVPGSVSVISREQLEDQPATDL--GDLLRRVPGVSVTSAGGG--AGQISIRGFGGGGNrvLV 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 181 LLNGQPINGMEDGNMYWSnwSGMSDVANAVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGGNDSYSKGTLS 260
Cdd:COG1629   75 LVDGVPLNDPSGGDGGLS--YIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSYGTYRASLS 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 261 YDSGLKESGWAFSVLVDHWQAFRKYSegtAGQGQNYLFSVGYKPSETHSFNFLLTGAPQWHDQNFSDELESYERYGEKYN 340
Cdd:COG1629  153 LSGGNGKLAYRLSASYRDSDGYRDNS---DSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDD 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 341 GNSGFLEGERFTERRNYYhkpvANLNWDYnINENLELSTVLYASwgrgggtgnvgngrvvnssnglidfdqiviNNINTA 420
Cdd:COG1629  230 GTNPYSNDTDDNTRDRYS----LSLEYEH-LGDGLKLSASAYYR------------------------------YDDTDL 274

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 421 DANGNGSFSNSYLRRSSVNAHNWYGLLSNLNYEAGENWSFNLgvdgrtyngihfrqlenKLGLNGYRDNFRTDRPSTyvi 500
Cdd:COG1629  275 DSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFGGKHTL-----------------LVGLDYQRQDLDGSGYPL--- 334

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 501 tetfkaNPWSALFDYADDDQRYDYNYEEviqyIGAFGQAEYK-MDNFSafIQTAISTQSYQREGFFTGRGNGLGKSEKlS 579
Cdd:COG1629  335 ------DLGSGSLPTLTSGADDDGTTTS----LALYAQDTYKlTDKLT--LTAGLRYDYVSYDVDDTVTGTDSASGSR-S 401

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 580 KEGYNLKGGLAYKINEQHTFFGNAGIYSRQPFLDNVFADIRYDNRLASPAVDNEEIIGFEGGYR--FKNDVFRLNIDIYN 657
Cdd:COG1629  402 YSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPYSVGNPDLKPETSTNYELGLRyrLLDGRLSLSLALFY 481

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 658 TEWGNRFLNINGPriaPNNDTSTYRLTDVTQVHRGLEFDFEYRPlASNFSLRGYgslgnwkydgetpYTLQNNETGDFit 737
Cdd:COG1629  482 SDVDNEILSVPLP---NDSGFSTYYTNAGKARSYGVELELSYQL-TPGLSLNAS-------------YSYTDAKFDDD-- 542

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 738 TNGKVSLTNVKVGNAPQTSFGIGLKGNLLENLSVDFDYNiYTDLYEFVDPADVAeealagrtyesiRLPAYTLADTGITY 817
Cdd:COG1629  543 TDGSADLDGNRLPGVPPLTANLGLTYEFPGGWSLGLGVR-YVGDRYLDDANTQG------------APGGYTLVDLGAGY 609

                        730       740
                 ....*....|....*....|....*
gi 765309964 818 VFNlgdNKLTFRGNVFNLFNTAYIN 842
Cdd:COG1629  610 RFG---DNLTLSLGVDNLFDKKYAT 631
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 126-865 4.25e-29

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 123.72  E-value: 4.25e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 126 VSTIKGKDIQLKSAGNVefGEALKNTPSVYVSNQAGGFGDsQIFLRGFDQVNTAYLLNGQPINGMEDGNMYWSNWSGMSD 205
Cdd:cd01347    2 VSVITAEDIEKQPATSL--ADLLRRIPGVSVTRGGGGGGS-TISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNTIPPEL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 206 VaNAVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGGNDSYSKGtlsydsglkeSGWAFSVLVDhwqafrky 285
Cdd:cd01347   79 I-ERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSS----------GGGGFDVSGA-------- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 286 seGTAGQGQNYLFSVGYKPSEThsfnflltgapqWHDQNFSDELESYERYGekyngnsgflegerfterrnyyhkpvANL 365
Cdd:cd01347  140 --LADDGAFGARLYGAYRDGDG------------TIDGDGQADDSDEERYN--------------------------VAG 179

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 366 NWDYNINENLELSTVLYASWGRGGGTGNVGNGRVVNSSNGLIDFDqiVINNINTADANGNGSFSNSYLRRSSVNAHNWYg 445
Cdd:cd01347  180 KLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPSS--NTNGDRDWDYRDRYRKRASLGLEHDLNDTGWT- 256

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 446 LLSNLNYEAGENWSFNLGVDGRTYNGihfrqlENKLGLNGYRDNFRTDRpstyvitETFKANpWSALFDYADDDQR---- 521
Cdd:cd01347  257 LRANLSYSYTDNDGDPLILNGGNNAA------GGDLGRSGYSSERDTTQ-------LGFDAG-LNAPFGTGPVAHTltlg 322

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 522 YDYNYEEVIQYI-GAFGQAEYKMDNfSAFIQTAIstqSYQREGFFTGRGNGLGKSEKLSKEGYNLKGGLAYKINEQHTFF 600
Cdd:cd01347  323 VEYRREELDEKQtALYAQDTIELTD-DLTLTLGL---RYDHYDQDSKDTIAGGTTAKKSYSHWSPSLGLVYKLTDGLSLY 398

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 601 GNAGIYSRQPFLDNVFADIRYDNR--LASPAVDNEEIIGFEGGYRFKNDV-FRLNIDIYNTEWGNRflnINGPRIAPNND 677
Cdd:cd01347  399 ASYSQGFRAPSLGELYGGGSHGGTaaVGNPNLKPEKSKQYELGLKYDPGDgLTLSAALFRIDIKNE---IVSTPTNTGLG 475

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 678 TSTYRLTDVTQVHRGLEFDFEYRpLASNFSLrgYGSlgnwkydgetpYTLQNNETGDFITTNgkvslTNVKVGNAPQTSF 757
Cdd:cd01347  476 LVTVYVNGGKARIRGVELEASYD-LTDGLGL--TGS-----------YTYTDTEVKRTDGAT-----TGNRLPGIPKHTA 536

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 758 GIGLKGNL-LENLSVDFDYNIYTDLYefvdpadvaeeALAGRTYESIRLPAYTLADTGITYVFNLGdnkLTFRGNVFNLF 836
Cdd:cd01347  537 NLGLDYELpDEGLTAGGGVRYRGKQY-----------ADTANGNNTVKVPGYTLVDLSASYQFTKN---LTLRLGVNNLF 602

                        730       740       750
                 ....*....|....*....|....*....|...
gi 765309964 837 NTAY----INQRDAFGYFLGIGRTWNASMRYNF 865
Cdd:cd01347  603 DKDYytslSVRGSGLYGYYGPGRTYYLSVSYKF 635
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 25-172 6.48e-25

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 111.53  E-value: 6.48e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964   25 TITGTITDAElNSPLPGANILEKGTTNGVSSDFDGNFTLETkKPNGQIVISFVGYQSITLKFSGNTSLgNIKLELDN-SL 103
Cdd:TIGR04056   2 TVTGVVVDET-GEPLIGASVVVKGTTNGTITDIDGNFSLKV-PPGAVLVFSYIGYKTQEVKVKGQKNL-NITLKEDTqEL 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 765309964  104 EEVVIIGTGV---IDLAEgretpvAVSTIKGKDIQLKSAGNveFGEALK-NTPSVYVSNQAGGFG-DSQIFLRG 172
Cdd:TIGR04056  79 DEVVVVGYGTqkkKSLTG------AVSTVKAKELKKVPVSN--LSNALQgKVAGVIITQSSGEPGgDAEIWIRG 144
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
 26-108 7.10e-19

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 81.87  E-value: 7.10e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964   26 ITGTITDAELNSPLPGANILEKGTTNGVSSDFDGNFTLeTKKPNGQ--IVISFVGYQS----ITLKFSGNTSLGNIKLEL 99
Cdd:pfam13715   1 ISGTVVDENTGEPLPGATVYVKGTTKGTVTDADGNFEL-KNLPAGTytLVVSFVGYKTqekkVTVSNDNTLDVNFLLKED 79


                  ....*....
gi 765309964  100 DNSLEEVVI 108
Cdd:pfam13715  80 ALLLDEVVV 88
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 408-864 1.38e-16

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 83.67  E-value: 1.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  408 DFDQIVINNINTADANGNGSFSNSYLRRSSVNAHNWYGLLSNLNYEAGENWSFNLGVDGRtYNGIHFRQLENKLGLNGYR 487
Cdd:pfam00593  27 GLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLR-YSSLDGDYTSNSSGLSGAG 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  488 DNFRTDRPSTYVITETFKANP----WSALFDYADDDQRYDYNYEEVIQYI-------GAFGQAEYKMDNFSAFIQTAIST 556
Cdd:pfam00593 106 DYLSDDRLYGLYGLDGDLELSldlsHDLLLGVELRTAGLDYRRLDDDAYDpydpanpSSSSYSDTTTDSYGLYLQDNIKL 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  557 QS---------YQREGFFTGRGNGLGKSEKLSKEGYNLKGGLAYKINEQHTFFGNAGIYSRQPFLDNVFADIRYDNRLAS 627
Cdd:pfam00593 186 TDrltltlglrYDHYSTDGDDGNGGGDNFSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGGGGAV 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  628 ----PAVDNEEIIGFEGGYRFKNDVFRLNIDIYNTEWGNRFLNINGPRIAPNNDTSTYRLTDVTqvHRGLEFDFEYRPLA 703
Cdd:pfam00593 266 aggnPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGPGLGGTVYTYTNVGKAR--IRGVELELSGRLWG 343

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  704 SNFSLrgygslgnwkydgeTPYTLQNNETGDFITTNGKvsltnvKVGNAPQTSFGIGLK-GNLLENLSVDFDYNiYTDLY 782
Cdd:pfam00593 344 LGLSG--------------GGYTYTDADDDADADDTGN------PLPNVPRHTANLGLTyDFPLGGWGARLGAR-YVGSG 402

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  783 EFVDpadvaeealaGRTYESIRLPAYTLADTGITYVFNlgdNKLTFRGNVFNLFNTAY----INQRDAFGYFLGIGRTWN 858
Cdd:pfam00593 403 ERRY----------GDAANTFKTPGYTLVDLSAGYRLN---KNLTLRLGVNNLFDKYYkryySSGGGNLGGYPGPGRTFY 469


                  ....*.
gi 765309964  859 ASMRYN 864
Cdd:pfam00593 470 LGLSYK 475
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 121-865 1.19e-14

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 78.22  E-value: 1.19e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  121 ETPVAVSTIKGKDIQLKSAGNVefGEALKNTPSVYVSNQAGGFGDSQIFLRGFDQVNTA--YLLNGQPingmedgnMYWS 198
Cdd:TIGR01783   1 DIPQSVSVITRQELEDQQAGSL--SEALQRVPGVVVGGSGGTTQFGNITIRGFGLEVDIdnVYLDGVP--------LLSR 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  199 NWSGMSDVAN--AVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGGNDSYSKGTLSYDSGLKESG-WAFSVL 275
Cdd:TIGR01783  71 GNLAIVDPAMveRVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSGYRTAFDLGGPLGADGtFRGRLN 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  276 VDHWQ--AFRKYSeGTAGQGQNYLFSVGYKPSETHSFNflltgapqwhdqnfsdelesYERYGEKYNGNSGFLEGERFTE 353
Cdd:TIGR01783 151 GARQDgdSFYDGA-GEETRLGATATDWQLDDRTLLRLG--------------------AYYQKERDRGGYGGLPASGGTS 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  354 RRNYyhkpvanlnwDYNINENLELSTVLYASWgrgggtgnvgngrvvnSSNGLIDFDQIViNNINTADANGNGS---FSN 430
Cdd:TIGR01783 210 GRDL----------SSDRYLGTSSNRNYDDRE----------------YLSYGLSLEYQF-NDVWTGKQNLRYSyfdTDS 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  431 SYLRRSSVNAHN-WYGLLSNLNYEAGENWSFNLGVDGRTyngiHFRQLENKLGLNGY-----RDNFRTDRPSTYVITETF 504
Cdd:TIGR01783 263 NQVQASGYSSDGgLFGRSLTVVNVKQDRVQIDAGLDGEF----ETGPIEHDLLLGVSygqrtTNRFNNTGYPSDNIYSLT 338

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  505 KANPWSALFDYADDDqRYDYNYeeviQYIGAFGQAEYKMDNfsafiQTAISTQSYQREGFFTGRGNGLGKS-EKLSKEGY 583
Cdd:TIGR01783 339 ATSSARTDIGDSPKD-RALSST----TKALNGVALQRILLA-----DKWTLTLGGRYDSVDVKSNNGVAGStGKRDDSQF 408

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  584 NLKGGLAYKINEQHTFFGNAGIYSRQPFLDNVFADirydnrLASPAVDNEEIIGFEGGYRFK-NDVFRLNIDIYNTEwgn 662
Cdd:TIGR01783 409 TPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAG------NSGDILEPEKGKNYELGVRYDlGDSLLATAALFRIT--- 479

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  663 rflNINGPRIAPNNDTSTYRLTDvtQVHRGLEFDFEYRPLasnFSLRGYGSlgnwkydgetpytlqnnetgdfittngkV 742
Cdd:TIGR01783 480 ---KDNQLVQDPVNGTFSVNAGK--TRNRGVELEARGYLT---PGLSLSAG----------------------------Y 523

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  743 SLTNVKVGNAPQtsfgIGLKGNLLEN-----LSVDFDYNIYTDLYEFVDPADVAeeaLAGRTY----ESIRLPAYTLADT 813
Cdd:TIGR01783 524 TYTDAEFTEDTN----GDTQGNTVPFvpkhtASLWASYAPPVGDNGLTLGGGVQ---YTGKAYvdggNTGKVPSYTVVDL 596

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 765309964  814 GITYVFNLGDNkLTFRGNVFNLFNTAYI---NQRDAFGY-FLGIGRTWNASMRYNF 865
Cdd:TIGR01783 597 SVRYDLTKKKN-LTLALNVNNLFDRDYYtsgYRWGPSAYiYPGAPRTVGLSVSYDF 651
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 100-243 3.23e-06

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 51.04  E-value: 3.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 100 DNSLEEVVIIGTGV-IDLAEGretPVAVSTIKGKDIQLKSAGNVEfgEALKNTPSVYVSNQaggfGDSQ--IFLRGFDQV 176
Cdd:PRK10064  27 DDDGETMVVTASAVeQNLKDA---PASISVITQEDLQRKPVQNLK--DVLKEVPGVQLTNE----GDNRkgVSIRGLDSS 97

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 177 NTAYLLNGQPINGME---DGNMYWSNWSGMsDVANAVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGG 243
Cdd:PRK10064  98 YTLILIDGKRVNSRNavfRHNDFDLNWIPV-DAIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQKWHG 166
 
Name Accession Description Interval E-value
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
103-842 2.12e-46

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 176.56  E-value: 2.12e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 103 LEEVVIIGTGVIDLAegRETPVAVSTIKGKDIQLKSAGNVefGEALKNTPSVYVSNQAGGfgDSQIFLRGFDQVNT--AY 180
Cdd:COG1629    1 LEEVVVTATRTDESL--QDVPGSVSVISREQLEDQPATDL--GDLLRRVPGVSVTSAGGG--AGQISIRGFGGGGNrvLV 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 181 LLNGQPINGMEDGNMYWSnwSGMSDVANAVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGGNDSYSKGTLS 260
Cdd:COG1629   75 LVDGVPLNDPSGGDGGLS--YIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSYGTYRASLS 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 261 YDSGLKESGWAFSVLVDHWQAFRKYSegtAGQGQNYLFSVGYKPSETHSFNFLLTGAPQWHDQNFSDELESYERYGEKYN 340
Cdd:COG1629  153 LSGGNGKLAYRLSASYRDSDGYRDNS---DSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDD 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 341 GNSGFLEGERFTERRNYYhkpvANLNWDYnINENLELSTVLYASwgrgggtgnvgngrvvnssnglidfdqiviNNINTA 420
Cdd:COG1629  230 GTNPYSNDTDDNTRDRYS----LSLEYEH-LGDGLKLSASAYYR------------------------------YDDTDL 274

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 421 DANGNGSFSNSYLRRSSVNAHNWYGLLSNLNYEAGENWSFNLgvdgrtyngihfrqlenKLGLNGYRDNFRTDRPSTyvi 500
Cdd:COG1629  275 DSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFGGKHTL-----------------LVGLDYQRQDLDGSGYPL--- 334

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 501 tetfkaNPWSALFDYADDDQRYDYNYEEviqyIGAFGQAEYK-MDNFSafIQTAISTQSYQREGFFTGRGNGLGKSEKlS 579
Cdd:COG1629  335 ------DLGSGSLPTLTSGADDDGTTTS----LALYAQDTYKlTDKLT--LTAGLRYDYVSYDVDDTVTGTDSASGSR-S 401

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 580 KEGYNLKGGLAYKINEQHTFFGNAGIYSRQPFLDNVFADIRYDNRLASPAVDNEEIIGFEGGYR--FKNDVFRLNIDIYN 657
Cdd:COG1629  402 YSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPYSVGNPDLKPETSTNYELGLRyrLLDGRLSLSLALFY 481

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 658 TEWGNRFLNINGPriaPNNDTSTYRLTDVTQVHRGLEFDFEYRPlASNFSLRGYgslgnwkydgetpYTLQNNETGDFit 737
Cdd:COG1629  482 SDVDNEILSVPLP---NDSGFSTYYTNAGKARSYGVELELSYQL-TPGLSLNAS-------------YSYTDAKFDDD-- 542

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 738 TNGKVSLTNVKVGNAPQTSFGIGLKGNLLENLSVDFDYNiYTDLYEFVDPADVAeealagrtyesiRLPAYTLADTGITY 817
Cdd:COG1629  543 TDGSADLDGNRLPGVPPLTANLGLTYEFPGGWSLGLGVR-YVGDRYLDDANTQG------------APGGYTLVDLGAGY 609

                        730       740
                 ....*....|....*....|....*
gi 765309964 818 VFNlgdNKLTFRGNVFNLFNTAYIN 842
Cdd:COG1629  610 RFG---DNLTLSLGVDNLFDKKYAT 631
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 81-820 4.79e-38

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 151.16  E-value: 4.79e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  81 SITLKFSGNTSLGNIKLELDNSLEEVVIIGTGVIDLAegRETPVAVSTIKGKDIQLKSAGNVefGEALKNTPSVYVSNQA 160
Cdd:COG4771    5 SLLLLLALAAQAADALAEDATELEEVVVTATRTEQSL--SDAPASVSVITAEEIEKLGATDL--ADALRLLPGVSVTRSG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 161 GGFGDSQIFLRGFDQVNTAYLLNGQPINGMEDGNMYWSNWSGMSDVANaVQIQRGLGASKLAISSVGGTVNIVSKTTDKK 240
Cdd:COG4771   81 GRGGSSGISIRGLGGDRVLVLIDGVPVNNPALGGGGDLSYIPPDDIER-IEVIRGPASALYGSDAIGGVINIITKKPTDE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 241 QGGFIRFLGGNDSYSKGTLSYDSGLKESGWAFSVLVDHWQA-------FRKYSEGTAGQGQNYLFSVGYKPSETHSFNFL 313
Cdd:COG4771  160 LEGSVSLGYGSNGNGTYSGSLSLGGPGDKLSFLLSGSYRDRdgyldyrNGGFVGNSGYERYNLNAKLGYRLSDNHRLSLS 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 314 LTGapqwhdqNFSDELESYERYGEKYNGNSGFLEGERFTERRNYyhkpvaNLNWDYNINENLELSTVlyaswgrgggtgn 393
Cdd:COG4771  240 GGY-------SRQDRDGGPPTLGDTEISSDNAGDRDTTTDRGNY------SLRYNGDLGDNLDLSLY------------- 293

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 394 vgngrvvnssnglidFDQIVINNINTADANGNGSFSNSYLRrssvnahnWYGLLSNLNYEAGENWSFNLGVDGRTYNgih 473
Cdd:COG4771  294 ---------------YSRTDRDSTNGSLGGSTGSFSDSDDT--------TYGLELDLTYPLGGNHTLTLGAEYRYDD--- 347

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 474 frqlenklglngyrdnfrtdrpstyvitetfkanpwsalfdyaDDDQRYDYNYEEVIQYIGAFGQAEYKM-DNFSafIQT 552
Cdd:COG4771  348 -------------------------------------------LDSSSFLGGADASRDTYGLFAQDEWKLtDKLT--LTA 382

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 553 AISTQSYQREGFFTgrgnglgkseklsKEGYNLKGGLAYKINEQHTFFGNAGIYSRQPFLDNVFADIRYDNR---LASPA 629
Cdd:COG4771  383 GLRYDYYSTFGASN-------------YTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGTPGryvLGNPD 449

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 630 VDNEEIIGFEGGYRFK--NDVFRLNIDIYNTEWGNRflnINGPRIAPNNDTSTYRLTDVTQVHRGLEFDFEYRpLASNFS 707
Cdd:COG4771  450 LKPETSDNYELGLEYRlgNGGLSLSLTGFYTDIKDL---IVLVPVGPGPGDVLQYENVGKARTYGLELELKYR-LGKGLT 525

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 708 LRGygslgnwkydgetPYTLQNNETGDFITTNgkvsltnvKVGNAPQTSFGIGLKGNLLENLSVDFDYNIYTDLYEFVDP 787
Cdd:COG4771  526 LTA-------------SYTYLDSKIDDGDTGE--------PLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVTPPS 584

                        730       740       750
                 ....*....|....*....|....*....|...
gi 765309964 788 ADVAEEalagrtyesirLPAYTLADTGITYVFN 820
Cdd:COG4771  585 GRLEGY-----------TPGYTLLDLRASYKLT 606
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
98-865 2.62e-37

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 149.69  E-value: 2.62e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  98 ELDNSLEEVVIIGTGvIDLAEGRETPVAVSTIKGKDIQLKSAGNVEfgEALKNTPSVYVSNQAGGFGDSQIFLRGFD--- 174
Cdd:COG4772   18 EAATTLETVVVTGSR-AAEARLKDVPGSVSVVDREELENQAATSLR--EVLRRVPGVNVQEEDGFGLRPNIGIRGLGprr 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 175 QVNTAYLLNGQPINGME--DGNMYWSNwsgMSDVANAVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGGND 252
Cdd:COG4772   95 SRGITLLEDGIPIAPAPygDPAAYYFP---DLERMERIEVLRGAAALRYGPQTVGGAINFVTRTIPTAFGGELRVTGGSF 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 253 SYSKGTLSYDSGLKESGWAFSVLVDHWQAFRkysEGTAGQGQNYLFSVGYKPSETHSFNFLLTgapqwhdqnfsdelesy 332
Cdd:COG4772  172 GYRRTHASVGGTVGNFGYLVEYSRKRGDGFR---DNSGFDINDFNAKLGYRLSDRQELTLKFQ----------------- 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 333 eRYGEKYNGNSG-----FLEGERFTERRNYYHKP---VANLNWDYNINENLELSTVLYASWGrgggtgnvgngrvvnssn 404
Cdd:COG4772  232 -YYDEDANTPGGltdaqFDADPRQSYRPADQFDTrrtQLSLRYEHQLSDNTTLTTTAYYNDF------------------ 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 405 gliDFDQIVINNINTADANGNGSFSNSYLRRSsvnahnwYGLLSNLNyeagenWSFNLGvdgrtynGIHFRqLEnkLGLN 484
Cdd:COG4772  293 ---SRNWYIRQNTADPNTPGLGLRGNPRGYRS-------YGIEPRLT------HRFELG-------GVPHT-LE--VGLR 346

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 485 GYRDNFrtdrpstyvitetfkanpwsalfdyadDDQRYDYNYEEVIQYIGAFGQAEYKMDNFSAFIQTAISTQ------- 557
Cdd:COG4772  347 YHREEE---------------------------DRKQYVNTYGQGRSGAGLRRDRRFSADALAAYAQNRFELTgrltltp 399

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 558 -------SYQREGFFTGRGNGlGKSEKLSKEGYNLKGGLAYKINEQHTFFGNAGiysrQPFLDNVFADIRYDNRLASPaV 630
Cdd:COG4772  400 glryehiRRDRTDRYSTRTGG-DDSGSNSYSEFLPGLGLLYQLTDNLQLYANVS----RGFEPPTFGDLAYGNGGNPD-L 473

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 631 DNEEIIGFEGGYRFK-NDVFRLNIDIYNTEWGNRFLNINgprIAPNNDTSTYRLTDVTqvHRGLEFDFEYRPL-ASNFSL 708
Cdd:COG4772  474 KPEKSWNYELGTRGRiGNGLSAEVALFYIDYDNELGSCS---AAGGDRSTFTNAGETR--HQGLELALDYDLLkGGGLGL 548

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 709 RGYGSlgnwkydgetpYTLQNNEtgdFITTNGKVSLTNvKVGNAP--QTSFGIGLKGNlleNLSVDFDYNiYTDLYeFVD 786
Cdd:COG4772  549 PLFAA-----------YTYTDAE---FTSDFGPVFAGN-RLPYVPrhQLTAGLGYEHG---GWTANLNGR-YVSEQ-FTD 608

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 787 PADVAEEALAGRTyesirlPAYTLADTGITYVFNlgdNKLTFRGNVFNLFNTAYINQR---DAFGYFLGIGRTWNASMRY 863
Cdd:COG4772  609 AANTVADGSFGKI------PSYTVLDLSASYDFG---KNLSLFAGVNNLFDKRYIASRapnYAAGIRPGPPRTVYAGLRL 679


                 ..
gi 765309964 864 NF 865
Cdd:COG4772  680 KF 681
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 120-865 1.38e-31

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 131.94  E-value: 1.38e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 120 RETPVAVSTIKGKDIQLKSAGNVefGEALKNTPSVYVSNQAGGFGDSqIFLRGFDQVNtaYLLNGQPINGMedgnmywsn 199
Cdd:COG4773   63 RETPQSVSVVTRQLIEDQGATTL--DDALRNVPGVTVSSYDGGGRDS-FSIRGFSIDN--YLRDGLPLGGF--------- 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 200 WSGMSDVANA--VQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGGNDSYSKGTLSYDSGLKESG-WAFSVLV 276
Cdd:COG4773  129 GGGQPDTANLerVEVLKGPAGLLYGAGSPGGLVNLVTKRPTAEPQGEVSLSAGSWDTYRATADVGGPLNEDGtLRYRLNA 208

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 277 DHWQA--FRKYSEGtagqgQNYLF--SVGYKPSETHSFNFLltgapqwhdqnfsdelesYERYGEKYNGNSGFL--EGER 350
Cdd:COG4773  209 AYEDGdsFRDGVDN-----RRTLIapSLDWDLTDDTTLTLG------------------AEYQDDDSTGDRGFLplDGTL 265

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 351 --------FTERRNYYHKPVANL--NWDYNINENLELSTVLYASwgrgggtgnvgngrvvnssnglidfdqivinninta 420
Cdd:COG4773  266 ldlprstnLGEPWDYYDTETTTLfaELEHRFNDDWSLRANARYS------------------------------------ 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 421 daNGNGSFSNSYLRRSSVNAHNWYGLLSNLNYEAGENWSFNLGVDGRTYNGihfrQLENKL--GLNGYRDNFRTDRPSTY 498
Cdd:COG4773  310 --DSDRDGRSAYAYGAPDAATGTLTRYASARDGDSRSDSLDANLNGKFETG----GLEHTLlvGADYSRYDSDSDSATAG 383

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 499 VItetfkaNPWSALFDYADDDQRYDYNYEEVIQYIGAFGQAEYK-MDNFSAFI---QTAISTQSYQREGfftgrgnglGK 574
Cdd:COG4773  384 TI------NIYNPVYGNLPEPDFDASDTDTTTRQTGLYAQDQISlTDRLSLLLggrYDWYETDSTNRLG---------GS 448

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 575 SEKLSKEGYNLKGGLAYKINEQHTFFGNagiYSrQPFLDNVFADIryDNRLASPavdnEEIIGFEGG--YRFKNDVFRLN 652
Cdd:COG4773  449 TTSYDDSAFTPRAGLVYDLTPGLSLYAS---YS-ESFEPQSGADN--NGNPLDP----ETGKQYEAGvkGELFDGRLNAT 518

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 653 IDIYNTEWGNRFlningpriAPNNDTSTYRLTDVTQVHRGLEFDFEYRPLAsNFSLrgYGSlgnwkydgetpYTLQNNE- 731
Cdd:COG4773  519 LAVFDITQKNVA--------TTDPDNPNFYVQVGEVRSRGVELELSGELTP-GLNL--IAG-----------YTYTDAKi 576

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 732 TGDFITTNGKvsltnvKVGNAPQTSFGIGLK----GNLLENLSVDFDYNiYTDlyefvdpadvaeeALAGRTYESIRLPA 807
Cdd:COG4773  577 TKDADALEGK------RLTNVPRHTASLWTTyrfpSGALKGLGLGGGVR-YVG-------------ERYGDAANTFTLPS 636

                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 765309964 808 YTLADTGITYVFNlgdNKLTFRGNVFNLFNTAYINQRDAFGY-FLGIGRTWNASMRYNF 865
Cdd:COG4773  637 YTLVDAGARYDLG---KNWTLQLNVNNLFDKKYYASSGSRGYvYYGAPRNVRLSLSYKF 692
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
120-865 2.64e-30

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 127.69  E-value: 2.64e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 120 RETPVAVSTIKGKDIQLKSAGNVEfgEALKNTPSVYVSNQAGGFGDsQIFLRGFDQVNTAYllngqpINGMEDGNMYwsn 199
Cdd:COG4774    7 LDTPQSVTVVTRELIEDQGATSLA--DALRNVPGVTFGAGEGGNGD-SFSIRGFSASGDIY------VDGLRDPGQY--- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 200 wsgMSDVANA--VQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGGNDSYSKGTLsyDSGL---KESGWAFSV 274
Cdd:COG4774   75 ---RRDTFNLerVEVLKGPASVLYGRGSPGGVINLVTKRPTDEPFTEVTLTYGSDGQRRATL--DVNGplgDDLAYRLNG 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 275 LVDHWQAFRKYSEgtagqGQNYLF--SVGYKPSETHSFNFLL----------TGAPQWHDQNFSDELESYeRYGEKYNgn 342
Cdd:COG4774  150 MYRDSDSYRDGVD-----NDRWGIapSLTWRLGDRTRLTLDYeyqdddrtpdYGVPAVANGRPVDVDRST-FYGQPDD-- 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 343 sgflegerFTERRNYyhkpVANLNWDYNINENLELSTVLYASWGRGGGtgnvgngrvvnssnglidfdqiviNNINTADA 422
Cdd:COG4774  222 --------YSDSETD----SATLRLEHDFNDNWTLRNALRYSDYDRDY------------------------RNTYPTGG 265

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 423 NGNGSFSNSYLRRSSVNahnwygllSNLNYEAGENWSFNLGvdgrtyngihfrQLENKL--GLNGYRdnFRTDRPSTYVI 500
Cdd:COG4774  266 NATGTVTRSAYRRDQDN--------DTLSNQTDLTGKFDTG------------GVKHTLlaGVEYSR--EDSDNARYSGG 323

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 501 TETFKANPWS-ALFDYADDDQRYDYNYEEVIQYIGAFGQAEYK------------MDNFSAFIQTAIS--TQSYQREGFF 565
Cdd:COG4774  324 GTAPTVNLYNpVYGAPVTGPTLGGADNDSRTDTTGLYLQDTISltdrwsllaglrYDRFDTDYTDRTTgaTTSSYDDSAF 403

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 566 TGRgnglgkseklskegynlkGGLAYKINEQHTFFGNAGiYSRQPFLDNVFADIrydnrlASPAVDNEEIIGFEGG--YR 643
Cdd:COG4774  404 SPR------------------AGLVYKPTPNLSLYASYS-TSFNPGGGAPSLSN------AGQALDPEKSRQYEVGvkWD 458

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 644 FKNDVFRLNIDIYNTEWGNRflningpRIAPNNDTSTYRLTDvTQVHRGLEFDFEYRPLAsnfSLRGYGSlgnwkydget 723
Cdd:COG4774  459 LLDGRLSLTAALFRIEKTNV-------RTTDPANPGVYVQTG-EQRSRGVELEATGELTP---GWSVLAG---------- 517

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 724 pYTLQNNEtgdfITTNGKVSLTNVKVGNAPQTSFGIGLKGNL-LENLSVDFDYNiYTDLYeFVDPADvaeealagrtyeS 802
Cdd:COG4774  518 -YTYLDAE----ITKSANAANVGNRLPNVPRHSASLWTTYDLpLPGLTLGGGVR-YVGSR-YADAAN------------T 578

                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 765309964 803 IRLPAYTLADTGITYVFNlgdNKLTFRGNVFNLFNTAYINQRDAFGY-FLGIGRTWNASMRYNF 865
Cdd:COG4774  579 VKLPSYTRFDAGASYRLN---KNLTLRLNVNNLTDKRYYASAYGSGYvTPGAPRTVLLSASYRF 639
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 126-865 4.25e-29

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 123.72  E-value: 4.25e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 126 VSTIKGKDIQLKSAGNVefGEALKNTPSVYVSNQAGGFGDsQIFLRGFDQVNTAYLLNGQPINGMEDGNMYWSNWSGMSD 205
Cdd:cd01347    2 VSVITAEDIEKQPATSL--ADLLRRIPGVSVTRGGGGGGS-TISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNTIPPEL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 206 VaNAVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGGNDSYSKGtlsydsglkeSGWAFSVLVDhwqafrky 285
Cdd:cd01347   79 I-ERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSS----------GGGGFDVSGA-------- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 286 seGTAGQGQNYLFSVGYKPSEThsfnflltgapqWHDQNFSDELESYERYGekyngnsgflegerfterrnyyhkpvANL 365
Cdd:cd01347  140 --LADDGAFGARLYGAYRDGDG------------TIDGDGQADDSDEERYN--------------------------VAG 179

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 366 NWDYNINENLELSTVLYASWGRGGGTGNVGNGRVVNSSNGLIDFDqiVINNINTADANGNGSFSNSYLRRSSVNAHNWYg 445
Cdd:cd01347  180 KLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPSS--NTNGDRDWDYRDRYRKRASLGLEHDLNDTGWT- 256

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 446 LLSNLNYEAGENWSFNLGVDGRTYNGihfrqlENKLGLNGYRDNFRTDRpstyvitETFKANpWSALFDYADDDQR---- 521
Cdd:cd01347  257 LRANLSYSYTDNDGDPLILNGGNNAA------GGDLGRSGYSSERDTTQ-------LGFDAG-LNAPFGTGPVAHTltlg 322

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 522 YDYNYEEVIQYI-GAFGQAEYKMDNfSAFIQTAIstqSYQREGFFTGRGNGLGKSEKLSKEGYNLKGGLAYKINEQHTFF 600
Cdd:cd01347  323 VEYRREELDEKQtALYAQDTIELTD-DLTLTLGL---RYDHYDQDSKDTIAGGTTAKKSYSHWSPSLGLVYKLTDGLSLY 398

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 601 GNAGIYSRQPFLDNVFADIRYDNR--LASPAVDNEEIIGFEGGYRFKNDV-FRLNIDIYNTEWGNRflnINGPRIAPNND 677
Cdd:cd01347  399 ASYSQGFRAPSLGELYGGGSHGGTaaVGNPNLKPEKSKQYELGLKYDPGDgLTLSAALFRIDIKNE---IVSTPTNTGLG 475

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 678 TSTYRLTDVTQVHRGLEFDFEYRpLASNFSLrgYGSlgnwkydgetpYTLQNNETGDFITTNgkvslTNVKVGNAPQTSF 757
Cdd:cd01347  476 LVTVYVNGGKARIRGVELEASYD-LTDGLGL--TGS-----------YTYTDTEVKRTDGAT-----TGNRLPGIPKHTA 536

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 758 GIGLKGNL-LENLSVDFDYNIYTDLYefvdpadvaeeALAGRTYESIRLPAYTLADTGITYVFNLGdnkLTFRGNVFNLF 836
Cdd:cd01347  537 NLGLDYELpDEGLTAGGGVRYRGKQY-----------ADTANGNNTVKVPGYTLVDLSASYQFTKN---LTLRLGVNNLF 602

                        730       740       750
                 ....*....|....*....|....*....|...
gi 765309964 837 NTAY----INQRDAFGYFLGIGRTWNASMRYNF 865
Cdd:cd01347  603 DKDYytslSVRGSGLYGYYGPGRTYYLSVSYKF 635
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 25-172 6.48e-25

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 111.53  E-value: 6.48e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964   25 TITGTITDAElNSPLPGANILEKGTTNGVSSDFDGNFTLETkKPNGQIVISFVGYQSITLKFSGNTSLgNIKLELDN-SL 103
Cdd:TIGR04056   2 TVTGVVVDET-GEPLIGASVVVKGTTNGTITDIDGNFSLKV-PPGAVLVFSYIGYKTQEVKVKGQKNL-NITLKEDTqEL 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 765309964  104 EEVVIIGTGV---IDLAEgretpvAVSTIKGKDIQLKSAGNveFGEALK-NTPSVYVSNQAGGFG-DSQIFLRG 172
Cdd:TIGR04056  79 DEVVVVGYGTqkkKSLTG------AVSTVKAKELKKVPVSN--LSNALQgKVAGVIITQSSGEPGgDAEIWIRG 144
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
106-385 6.37e-24

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 102.64  E-value: 6.37e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 106 VVIIGTGVIdlAEGRETPVAVSTIKGKDIQLKSAGNVefGEALKNTPSVYVSNQAGGFGDSQIFLRGFDQVNTAYLLNGQ 185
Cdd:COG4206    1 VVVTATRLE--QSKSDLTGSVTVIDAEELERSGATSL--ADALRRVPGVQVSSSGGPGSAASISIRGLGSNQTLVLIDGV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 186 PINGMEDGNMYWSNWSgMSDVANaVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGGNDSYSKGTLSYDSGL 265
Cdd:COG4206   77 PLNDPSLGGVDLSLIP-PDDIER-IEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSASYGSFGTRRLSASLSGGA 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 266 KESGWAFSVLVDHWQAFRKYSEGTAG----QGQNYLFSVGYKPSETHSFNFllTGAPQWHDQNFSDELESYERYGEKYNG 341
Cdd:COG4206  155 GKFSYSLSASYRRSDGYRYNDPDLRNndgyENTSLNARLGYKLGDNGSLSL--SGGYSDSERGYPGAVGSDRNLRLSLSL 232

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 765309964 342 NSGFLEGERFTERRNYYHKPVANLNWDYNINENLELSTVLYASW 385
Cdd:COG4206  233 EYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAGLSY 276
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
 26-108 7.10e-19

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 81.87  E-value: 7.10e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964   26 ITGTITDAELNSPLPGANILEKGTTNGVSSDFDGNFTLeTKKPNGQ--IVISFVGYQS----ITLKFSGNTSLGNIKLEL 99
Cdd:pfam13715   1 ISGTVVDENTGEPLPGATVYVKGTTKGTVTDADGNFEL-KNLPAGTytLVVSFVGYKTqekkVTVSNDNTLDVNFLLKED 79


                  ....*....
gi 765309964  100 DNSLEEVVI 108
Cdd:pfam13715  80 ALLLDEVVV 88
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 408-864 1.38e-16

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 83.67  E-value: 1.38e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  408 DFDQIVINNINTADANGNGSFSNSYLRRSSVNAHNWYGLLSNLNYEAGENWSFNLGVDGRtYNGIHFRQLENKLGLNGYR 487
Cdd:pfam00593  27 GLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLR-YSSLDGDYTSNSSGLSGAG 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  488 DNFRTDRPSTYVITETFKANP----WSALFDYADDDQRYDYNYEEVIQYI-------GAFGQAEYKMDNFSAFIQTAIST 556
Cdd:pfam00593 106 DYLSDDRLYGLYGLDGDLELSldlsHDLLLGVELRTAGLDYRRLDDDAYDpydpanpSSSSYSDTTTDSYGLYLQDNIKL 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  557 QS---------YQREGFFTGRGNGLGKSEKLSKEGYNLKGGLAYKINEQHTFFGNAGIYSRQPFLDNVFADIRYDNRLAS 627
Cdd:pfam00593 186 TDrltltlglrYDHYSTDGDDGNGGGDNFSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGGGGAV 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  628 ----PAVDNEEIIGFEGGYRFKNDVFRLNIDIYNTEWGNRFLNINGPRIAPNNDTSTYRLTDVTqvHRGLEFDFEYRPLA 703
Cdd:pfam00593 266 aggnPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGPGLGGTVYTYTNVGKAR--IRGVELELSGRLWG 343

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  704 SNFSLrgygslgnwkydgeTPYTLQNNETGDFITTNGKvsltnvKVGNAPQTSFGIGLK-GNLLENLSVDFDYNiYTDLY 782
Cdd:pfam00593 344 LGLSG--------------GGYTYTDADDDADADDTGN------PLPNVPRHTANLGLTyDFPLGGWGARLGAR-YVGSG 402

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  783 EFVDpadvaeealaGRTYESIRLPAYTLADTGITYVFNlgdNKLTFRGNVFNLFNTAY----INQRDAFGYFLGIGRTWN 858
Cdd:pfam00593 403 ERRY----------GDAANTFKTPGYTLVDLSAGYRLN---KNLTLRLGVNNLFDKYYkryySSGGGNLGGYPGPGRTFY 469


                  ....*.
gi 765309964  859 ASMRYN 864
Cdd:pfam00593 470 LGLSYK 475
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 121-865 1.19e-14

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 78.22  E-value: 1.19e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  121 ETPVAVSTIKGKDIQLKSAGNVefGEALKNTPSVYVSNQAGGFGDSQIFLRGFDQVNTA--YLLNGQPingmedgnMYWS 198
Cdd:TIGR01783   1 DIPQSVSVITRQELEDQQAGSL--SEALQRVPGVVVGGSGGTTQFGNITIRGFGLEVDIdnVYLDGVP--------LLSR 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  199 NWSGMSDVAN--AVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGGNDSYSKGTLSYDSGLKESG-WAFSVL 275
Cdd:TIGR01783  71 GNLAIVDPAMveRVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSGYRTAFDLGGPLGADGtFRGRLN 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  276 VDHWQ--AFRKYSeGTAGQGQNYLFSVGYKPSETHSFNflltgapqwhdqnfsdelesYERYGEKYNGNSGFLEGERFTE 353
Cdd:TIGR01783 151 GARQDgdSFYDGA-GEETRLGATATDWQLDDRTLLRLG--------------------AYYQKERDRGGYGGLPASGGTS 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  354 RRNYyhkpvanlnwDYNINENLELSTVLYASWgrgggtgnvgngrvvnSSNGLIDFDQIViNNINTADANGNGS---FSN 430
Cdd:TIGR01783 210 GRDL----------SSDRYLGTSSNRNYDDRE----------------YLSYGLSLEYQF-NDVWTGKQNLRYSyfdTDS 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  431 SYLRRSSVNAHN-WYGLLSNLNYEAGENWSFNLGVDGRTyngiHFRQLENKLGLNGY-----RDNFRTDRPSTYVITETF 504
Cdd:TIGR01783 263 NQVQASGYSSDGgLFGRSLTVVNVKQDRVQIDAGLDGEF----ETGPIEHDLLLGVSygqrtTNRFNNTGYPSDNIYSLT 338

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  505 KANPWSALFDYADDDqRYDYNYeeviQYIGAFGQAEYKMDNfsafiQTAISTQSYQREGFFTGRGNGLGKS-EKLSKEGY 583
Cdd:TIGR01783 339 ATSSARTDIGDSPKD-RALSST----TKALNGVALQRILLA-----DKWTLTLGGRYDSVDVKSNNGVAGStGKRDDSQF 408

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  584 NLKGGLAYKINEQHTFFGNAGIYSRQPFLDNVFADirydnrLASPAVDNEEIIGFEGGYRFK-NDVFRLNIDIYNTEwgn 662
Cdd:TIGR01783 409 TPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAG------NSGDILEPEKGKNYELGVRYDlGDSLLATAALFRIT--- 479

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  663 rflNINGPRIAPNNDTSTYRLTDvtQVHRGLEFDFEYRPLasnFSLRGYGSlgnwkydgetpytlqnnetgdfittngkV 742
Cdd:TIGR01783 480 ---KDNQLVQDPVNGTFSVNAGK--TRNRGVELEARGYLT---PGLSLSAG----------------------------Y 523

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  743 SLTNVKVGNAPQtsfgIGLKGNLLEN-----LSVDFDYNIYTDLYEFVDPADVAeeaLAGRTY----ESIRLPAYTLADT 813
Cdd:TIGR01783 524 TYTDAEFTEDTN----GDTQGNTVPFvpkhtASLWASYAPPVGDNGLTLGGGVQ---YTGKAYvdggNTGKVPSYTVVDL 596

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 765309964  814 GITYVFNLGDNkLTFRGNVFNLFNTAYI---NQRDAFGY-FLGIGRTWNASMRYNF 865
Cdd:TIGR01783 597 SVRYDLTKKKN-LTLALNVNNLFDRDYYtsgYRWGPSAYiYPGAPRTVGLSVSYDF 651
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 120-229 1.51e-14

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 70.38  E-value: 1.51e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  120 RETPVAVSTIKGKDIQLKSAGNVefGEALKNTPSVYVSNQAGGfGDSQIFLRGFDQVNTAYLLNGQPINGMEDGNMYWSN 199
Cdd:pfam07715   3 RDTPGSVSVVTAEDIEDQGATNL--ADALRGVPGVSVSSGGGG-GGSSISIRGFGSNRVLVLVDGVPLNSGGGGSVDLNS 79

                          90       100       110
                  ....*....|....*....|....*....|
gi 765309964  200 WSgMSDVAnAVQIQRGLGASKLAISSVGGT 229
Cdd:pfam07715  80 ID-PEDIE-RVEVLKGPASALYGSGAIGGV 107
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
 103-865 7.54e-14

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 75.51  E-value: 7.54e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  103 LEEVVIIGTGVIDLAEgrETPVAVSTIKGKDIQLKSAGNVefGEALKNTPSVYVSnqaGGFGDS--QIFLRGFDQVNTAY 180
Cdd:TIGR01785   1 LDTVTVTATRTRQVLS--EAPASVSVISGEQIESKQANNL--ADALNTVPGVDVT---GGGRPPgqSINIRGLQDNRVLV 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  181 LLNGQPINGMEDGNMYWSNWSGMSDVaNAVQIQRGLGASKLAISSVGGTVNIVSKTT-DKKQGGfiRFLGGNDSYSKGTL 259
Cdd:TIGR01785  74 VVDGARQNYQRGGAHNGSLFVDPELL-KRIEIVKGPSSSLYGSGALGGVVAFRTKDAaDLLRPG--QLFGGLAKLSYGSN 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  260 SYDSGlkESGWAFSVLVDHWQAFRKYSEGTAG---------------QGQNYLFSVGYKPSETHSFNFLLtGAPQWHDQN 324
Cdd:TIGR01785 151 NNSFG--GSVAVAGRLDDNLDALVAATYRDGGnyrngnkeeatnsayVQKNLLAKLGWQLDDAQRLEFSY-FTTEGSLDE 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  325 FSDELESYErygekYNGNSGFLEGERFTERRNYyhkpvaNLNWDYNINENLELSTVLYASWGRGGgtgnvgngrvvnssn 404
Cdd:TIGR01785 228 AQNSGPGTE-----YVLGSSSTLLASSTRDRSA------TLTYNWTPEDNPWLDATASLYYNRTE--------------- 281

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  405 glidfdqivINNINTADANGNGSFSNSYLRRSSVNAHNWYGLLSNLNyeagenwsFNLGVDGrtyngihfrqlenklgln 484
Cdd:TIGR01785 282 ---------NDNDRSARGVGREEGYQYTTYGATLQNTSRFDVASWST--------LTYGVDW------------------ 326

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  485 gYRDNFRTDRpstyvitetfkanpwsalFDYADDDQRYDYNYEEVIQYIGAFGQAEYKMDNfsafiqTAISTQSYQREGF 564
Cdd:TIGR01785 327 -MKDKRRTES------------------FDPNSVTTIVPNPPSAKEYFFGLFLQDNIPLLD------DRLTLSAGLRYDH 381

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  565 FTGRGNGlGKSEKLSKEGYNL---KGGLAYKINEQHTFFGNAGIYSRQPFLDNV------FADIRYDNRLASPAVDNEEI 635
Cdd:TIGR01785 382 YKLSPKT-TADTEAVDRSYSRwspSLGLSYKPVDWLTLYASYSQGFRAPSIDELygtgdhPGTPGGYTFAPNPNLKPETS 460

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  636 IGFEGGYRFK-------NDVFRLNIDIYNTEWGNrFLNINGPRIAP----NNDTSTYRLTDVTQVhRGLEFDFEYRplas 704
Cdd:TIGR01785 461 KTWELGANLSfdnllldNDQLQFKVAYFYNDVKD-FIDLTIGVTDNvtagMNNITQYVNIDGARI-RGIEASASYD---- 534

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  705 nfslrgygsLGNWKydGETPYTlqnnetgdfiTTNGKVSLTNVKVGNAPQTSFGIGLKGNLlenlsvdFDYNIYTDLY-E 783
Cdd:TIGR01785 535 ---------AGLWA--TGLSYG----------YTIGKDQNTNQWLSNIPPLKLVVTVGYRF-------PDRRLDLGAKaA 586

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  784 FVDPADVAEEALAGRTYESIRLPAYTLADTGITYVFNlGDNKLTFRGNVFNLFNTAYINQRDAFGyfLGIGRTWNASMRY 863
Cdd:TIGR01785 587 YYERQSESPTTEDVAANGLLTTPGYTVVDLYATYQPN-AVKGLTVRFGVNNLTDRKYTPAQSVPG--AGPGRNFKGSVKY 663


                  ..
gi 765309964  864 NF 865
Cdd:TIGR01785 664 QF 665
CarboxypepD_reg pfam13620
Carboxypeptidase regulatory-like domain;
25-85 1.57e-06

Carboxypeptidase regulatory-like domain;


Pssm-ID: 433354 [Multi-domain]  Cd Length: 81  Bit Score: 46.50  E-value: 1.57e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 765309964   25 TITGTITDAElNSPLPGANI----LEKGTTNGVSSDFDGNFTLeTKKPNG--QIVISFVGYQSITLK 85
Cdd:pfam13620   1 TISGTVTDPS-GAPVPGATVtvtnTDTGTVRTTTTDADGRYRF-PGLPPGtyTVTVSAPGFKTATRT 65
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 100-243 3.23e-06

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 51.04  E-value: 3.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 100 DNSLEEVVIIGTGV-IDLAEGretPVAVSTIKGKDIQLKSAGNVEfgEALKNTPSVYVSNQaggfGDSQ--IFLRGFDQV 176
Cdd:PRK10064  27 DDDGETMVVTASAVeQNLKDA---PASISVITQEDLQRKPVQNLK--DVLKEVPGVQLTNE----GDNRkgVSIRGLDSS 97

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 177 NTAYLLNGQPINGME---DGNMYWSNWSGMsDVANAVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGG 243
Cdd:PRK10064  98 YTLILIDGKRVNSRNavfRHNDFDLNWIPV-DAIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQKWHG 166
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
100-343 2.35e-03

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 41.53  E-value: 2.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 100 DNSLEEVVIIGTGVIDlaEGRETPVAVSTIKGKDIQLKSAGNVefGEALKNTPSVYVSnqaGGFGDSQIFLRGFDQVNTA 179
Cdd:PRK13484  27 DKKEDTLVVTASGFTQ--QLRNAPASVSVITSEQLQKKPVSDL--VDAVKDVEGISIT---GGNEKPDISIRGLSGDYTL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 180 YLLNGQPINGMED----GNMYWSNWSGMSDVANAVQIQRGLGASKLAISSVGGTVNIVSKTTDKKQGGFIRFLGG----- 250
Cdd:PRK13484 100 ILVDGRRQSGRESrpngSGGFEAGFIPPVEAIERIEVIRGPMSSLYGSDAIGGVINIITKPVNNQTWDGVLGLGGiiqeh 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 251 --------NDSYSKGTLSYDS-GLKESGWAFsvlvdhwqaFRKYSEGTAGQG----QNYLFSVGYKPSETHSFNFLLTGA 317
Cdd:PRK13484 180 gkfgnsttNDFYLSGPLIKDKlGLQLYGGMN---------YRKEDSISQGTPakdnKNITATLQFTPTESQKFVFEYGKN 250

                        250       260
                 ....*....|....*....|....*.
gi 765309964 318 PQWHDQNFSDELESYERYGEKYNGNS 343
Cdd:PRK13484 251 NQVHTLTPGESLDAWTMRGNLKQPNS 276
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 81-242 3.71e-03

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 40.90  E-value: 3.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964  81 SITLKFSGNTSLGNIKLELDNSLEEVVIIGTGVIDLaegRETPvAVSTIKGKDIQLKSAGNvEFGEALKNTPSVYVS-NQ 159
Cdd:PRK13528  12 LTVLLVGLNSPVSAAESSDDDNGETMVVEATAEQEL---KQQP-GVSIITAEDIKKRPPVN-DLSDIIRKMPGVNLTgNS 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765309964 160 AGG-FGDS-QIFLRGFDQVNTAYLLNGQPINGMEDGNMYW---------SNWSGMSDVANaVQIQRGLGASKLAISSVGG 228
Cdd:PRK13528  87 ASGtRGNNrQIDIRGMGPENTLILIDGVPVTSRNSVRYSWrgerdtrgdTNWVPPEMVER-IEVIRGPAAARYGSGAAGG 165

                        170
                 ....*....|....*
gi 765309964 229 TVNIVSKT-TDKKQG 242
Cdd:PRK13528 166 VVNIITKRpTNDWHG 180
PRK13483 PRK13483
ligand-gated channel protein;
797-865 4.53e-03

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 40.53  E-value: 4.53e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 765309964 797 GRTYESIRLPAYTLADTGITYVFNlgdNKLTFRGNVFNLFNTAyINQRDaFGYFLGIGRTWnASMRYNF 865
Cdd:PRK13483 598 GPSSSSFIAPSYTFLDLGANYQLT---DNLKLSAGIYNLFDKE-INYEE-YGYVEDGRRYW-LGMTYSF 660
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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