NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|765522945|ref|WP_044735180|]
View 

hypothetical protein [Shewanella algae]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ZnPC_S1P1 super family cl16915
Zinc dependent phospholipase C/S1-P1 nuclease; This model describes both the bacterial and ...
 81-160 1.51e-06

Zinc dependent phospholipase C/S1-P1 nuclease; This model describes both the bacterial and archeal zinc-dependent phospholipase C, a domain found in the alpha toxin of Clostridium perfringens, as well as S1/P1 nucleases, which predominantly act on single-stranded DNA and RNA.


The actual alignment was detected with superfamily member cd11009:

Pssm-ID: 450122  Cd Length: 218  Bit Score: 48.53  E-value: 1.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765522945  81 WSDQLFPAYRRVGNwHFYHPDKTDKETVQPGLVNMSQQrLWARAqLGLTMANDSTQRDYFVGALLHLLQDVSVPAHVTPV 160
Cdd:cd11009   48 WADQDWKSGDQYVN-HFYDPDTGKGLYGFPTALTEFRK-YYDLA-LEYWRKGDYEKAMFYLGRALHYLQDLTVPHHAANA 124
 
Name Accession Description Interval E-value
Zn_dep_PLPC cd11009
Zinc dependent phospholipase C (alpha toxin); This domain conveys a zinc dependent ...
 81-160 1.51e-06

Zinc dependent phospholipase C (alpha toxin); This domain conveys a zinc dependent phospholipase C activity (EC 3.1.4.3). It is found in a monomeric phospholipase C of Bacillus cereus as well as in the alpha toxin of Clostridium perfringens and Clostridium bifermentans, which is involved in haemolysis and cell rupture. It is also found in a lecithinase of Listeria monocytogenes, which is involved in breaking the 2-membrane vacuoles that surround the bacterium.


Pssm-ID: 211381  Cd Length: 218  Bit Score: 48.53  E-value: 1.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765522945  81 WSDQLFPAYRRVGNwHFYHPDKTDKETVQPGLVNMSQQrLWARAqLGLTMANDSTQRDYFVGALLHLLQDVSVPAHVTPV 160
Cdd:cd11009   48 WADQDWKSGDQYVN-HFYDPDTGKGLYGFPTALTEFRK-YYDLA-LEYWRKGDYEKAMFYLGRALHYLQDLTVPHHAANA 124
 
Name Accession Description Interval E-value
Zn_dep_PLPC cd11009
Zinc dependent phospholipase C (alpha toxin); This domain conveys a zinc dependent ...
 81-160 1.51e-06

Zinc dependent phospholipase C (alpha toxin); This domain conveys a zinc dependent phospholipase C activity (EC 3.1.4.3). It is found in a monomeric phospholipase C of Bacillus cereus as well as in the alpha toxin of Clostridium perfringens and Clostridium bifermentans, which is involved in haemolysis and cell rupture. It is also found in a lecithinase of Listeria monocytogenes, which is involved in breaking the 2-membrane vacuoles that surround the bacterium.


Pssm-ID: 211381  Cd Length: 218  Bit Score: 48.53  E-value: 1.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 765522945  81 WSDQLFPAYRRVGNwHFYHPDKTDKETVQPGLVNMSQQrLWARAqLGLTMANDSTQRDYFVGALLHLLQDVSVPAHVTPV 160
Cdd:cd11009   48 WADQDWKSGDQYVN-HFYDPDTGKGLYGFPTALTEFRK-YYDLA-LEYWRKGDYEKAMFYLGRALHYLQDLTVPHHAANA 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH