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Conserved domains on  [gi|766606098|ref|WP_044784921|]
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MULTISPECIES: transcriptional regulator [Klebsiella]

Protein Classification

transcriptional regulator( domain architecture ID 11459460)

transcriptional regulator containing a PAS and a DNA-binding helix-turn-helix domain

Gene Ontology:  GO:0003677|GO:0140110

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
8-207 7.55e-66

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


:

Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 202.00  E-value: 7.55e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 766606098   8 EQQLELLKSIAEGIVALFFPGVEVVIHNAST--RKIAYIAN-NLSKRKSGD---EAGIDDIRMSCANE--ISGPYEKLNW 79
Cdd:COG2964    6 KELLESYIPIADGLAALFGPNCEVVLHDLEDpeHSIVAIANgHVSGRKVGDpitDLGLELLKDGAYEDpdVIGNYETRTK 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 766606098  80 DGRKMRSVSIYtsI---DGRPSYIMCVNLNTTIFEDARNALDMFLSVTRLQPQPQQLFKDDWQENINTFLHEWIKKENAS 156
Cdd:COG2964   86 DGRLLKSSTIF--IrdeKGKPIGALCINFDLSKFEAAQNFLDSFLPTDDSEEEPPENFASDVEELIDEIIDEALAEVGKP 163
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 766606098 157 LTSLNREQKKRIVVDLYHEGAFKAKNAVDYIASVLVMGRATVYKYLREVKN 207
Cdd:COG2964  164 PSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
 
Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
8-207 7.55e-66

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 202.00  E-value: 7.55e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 766606098   8 EQQLELLKSIAEGIVALFFPGVEVVIHNAST--RKIAYIAN-NLSKRKSGD---EAGIDDIRMSCANE--ISGPYEKLNW 79
Cdd:COG2964    6 KELLESYIPIADGLAALFGPNCEVVLHDLEDpeHSIVAIANgHVSGRKVGDpitDLGLELLKDGAYEDpdVIGNYETRTK 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 766606098  80 DGRKMRSVSIYtsI---DGRPSYIMCVNLNTTIFEDARNALDMFLSVTRLQPQPQQLFKDDWQENINTFLHEWIKKENAS 156
Cdd:COG2964   86 DGRLLKSSTIF--IrdeKGKPIGALCINFDLSKFEAAQNFLDSFLPTDDSEEEPPENFASDVEELIDEIIDEALAEVGKP 163
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 766606098 157 LTSLNREQKKRIVVDLYHEGAFKAKNAVDYIASVLVMGRATVYKYLREVKN 207
Cdd:COG2964  164 PSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
PAS_6 pfam08348
YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are ...
11-116 2.62e-25

YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are similar to the E. coli protein YheO. Their function is unknown, but are likely to be involved in signalling based on the presence of this PAS domain.


Pssm-ID: 429938 [Multi-domain]  Cd Length: 115  Bit Score: 95.28  E-value: 2.62e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 766606098   11 LELLKSIAEGIVALFFPGVEVVIHNAST--RKIAYIAN-NLSKRKSGD---EAGIDDIRMSCANE--ISGPYEKLNWDGR 82
Cdd:pfam08348   1 LESYIPIADGLAETFGPNCEVVLHDLRDpeHSIVAIANgHVTGRKVGDpitDLALELLKQEEYEEkdYLINYKTKTKDGR 80
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 766606098   83 KMRSVSIYtsI---DGRPSYIMCVNLNTTIFEDARNA 116
Cdd:pfam08348  81 ILKSSTIF--IrdeDGKIIGLLCINFDITALLAAQNA 115
 
Name Accession Description Interval E-value
YheO COG2964
Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains ...
8-207 7.55e-66

Predicted transcriptional regulator YheO, contains PAS and DNA-binding HTH domains [Transcription];


Pssm-ID: 442204 [Multi-domain]  Cd Length: 214  Bit Score: 202.00  E-value: 7.55e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 766606098   8 EQQLELLKSIAEGIVALFFPGVEVVIHNAST--RKIAYIAN-NLSKRKSGD---EAGIDDIRMSCANE--ISGPYEKLNW 79
Cdd:COG2964    6 KELLESYIPIADGLAALFGPNCEVVLHDLEDpeHSIVAIANgHVSGRKVGDpitDLGLELLKDGAYEDpdVIGNYETRTK 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 766606098  80 DGRKMRSVSIYtsI---DGRPSYIMCVNLNTTIFEDARNALDMFLSVTRLQPQPQQLFKDDWQENINTFLHEWIKKENAS 156
Cdd:COG2964   86 DGRLLKSSTIF--IrdeKGKPIGALCINFDLSKFEAAQNFLDSFLPTDDSEEEPPENFASDVEELIDEIIDEALAEVGKP 163
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 766606098 157 LTSLNREQKKRIVVDLYHEGAFKAKNAVDYIASVLVMGRATVYKYLREVKN 207
Cdd:COG2964  164 PSALSKEEKIEIVRELDEKGIFLIKGAVDYVAKRLGISRATVYNYLREIKK 214
PAS_6 pfam08348
YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are ...
11-116 2.62e-25

YheO-like PAS domain; This family contains various hypothetical bacterial proteins that are similar to the E. coli protein YheO. Their function is unknown, but are likely to be involved in signalling based on the presence of this PAS domain.


Pssm-ID: 429938 [Multi-domain]  Cd Length: 115  Bit Score: 95.28  E-value: 2.62e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 766606098   11 LELLKSIAEGIVALFFPGVEVVIHNAST--RKIAYIAN-NLSKRKSGD---EAGIDDIRMSCANE--ISGPYEKLNWDGR 82
Cdd:pfam08348   1 LESYIPIADGLAETFGPNCEVVLHDLRDpeHSIVAIANgHVTGRKVGDpitDLALELLKQEEYEEkdYLINYKTKTKDGR 80
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 766606098   83 KMRSVSIYtsI---DGRPSYIMCVNLNTTIFEDARNA 116
Cdd:pfam08348  81 ILKSSTIF--IrdeDGKIIGLLCINFDITALLAAQNA 115
HTH_22 pfam13309
HTH domain; This domain is a helix-turn-helix domain that is likely to act as a DNA-binding ...
142-203 5.27e-18

HTH domain; This domain is a helix-turn-helix domain that is likely to act as a DNA-binding domain.


Pssm-ID: 463841 [Multi-domain]  Cd Length: 63  Bit Score: 74.42  E-value: 5.27e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 766606098  142 INTFLHEWIKKENASLTSLNREQKKRIVVDLYHEGAFKAKNAVDYIASVLVMGRATVYKYLR 203
Cdd:pfam13309   2 LDSIIDEVLADVGKPPARLTKEEKREIVRALDEKGAFLLKGAVEKVAKRLGVSRATVYNYLR 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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