jacalin family lectin is a sugar-binding protein containing a jacalin domain| zinc metalloproteinase family protein contains an HEXXH motif characteristic of metallopeptidases; contains a Jacalin-like lectin domain that may bind mono- or oligosaccharides
Family of unknown function (DUF6765); This family of proteins is functionally uncharacterized. ...
1-373
4.93e-70
Family of unknown function (DUF6765); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 352 and 375 amino acids in length. It contains the conserved motifs FHFxxxP, GH and PD, and a conserved Phe residue at the C-terminal.
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Pssm-ID: 466700 Cd Length: 304 Bit Score: 227.28 E-value: 4.93e-70
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
390-519
2.30e-13
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.
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Pssm-ID: 187706 Cd Length: 128 Bit Score: 67.04 E-value: 2.30e-13
Family of unknown function (DUF6765); This family of proteins is functionally uncharacterized. ...
1-373
4.93e-70
Family of unknown function (DUF6765); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 352 and 375 amino acids in length. It contains the conserved motifs FHFxxxP, GH and PD, and a conserved Phe residue at the C-terminal.
Pssm-ID: 466700 Cd Length: 304 Bit Score: 227.28 E-value: 4.93e-70
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
390-519
2.30e-13
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.
Pssm-ID: 187706 Cd Length: 128 Bit Score: 67.04 E-value: 2.30e-13
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
391-519
2.41e-07
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.
Pssm-ID: 214909 [Multi-domain] Cd Length: 128 Bit Score: 49.92 E-value: 2.41e-07
Family of unknown function (DUF6765); This family of proteins is functionally uncharacterized. ...
1-373
4.93e-70
Family of unknown function (DUF6765); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 352 and 375 amino acids in length. It contains the conserved motifs FHFxxxP, GH and PD, and a conserved Phe residue at the C-terminal.
Pssm-ID: 466700 Cd Length: 304 Bit Score: 227.28 E-value: 4.93e-70
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
390-519
2.30e-13
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.
Pssm-ID: 187706 Cd Length: 128 Bit Score: 67.04 E-value: 2.30e-13
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
391-519
2.41e-07
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.
Pssm-ID: 214909 [Multi-domain] Cd Length: 128 Bit Score: 49.92 E-value: 2.41e-07
Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a ...
391-491
3.11e-07
Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a conserved secreted vertebrate protein with tissue-specific expression profiles, which might play a role in glycoprotein secretion, perhaps as a linker protein that participates in the formation and/or transport of the zymogen granule. Its paralog ZG16b (PAUF) has been associated with roles in gene regulation and cancer. This domain family also contains mammalian proteins labelled as prostatic spermine-binding protein (SBP) and salivary-gland specific secreted proteins.
Pssm-ID: 187707 [Multi-domain] Cd Length: 128 Bit Score: 49.63 E-value: 3.11e-07
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
393-494
4.87e-07
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.
Pssm-ID: 187708 [Multi-domain] Cd Length: 130 Bit Score: 49.10 E-value: 4.87e-07
Jacalin-like lectin domains of putative endonucleases/exonucleases/phosphatases and related ...
404-512
3.87e-06
Jacalin-like lectin domains of putative endonucleases/exonucleases/phosphatases and related proteins; Members of this taxonomically diverse family co-occur with metal-dependent endonucleases/exonucleases/phosphatases. They have not been functionally characterized.
Pssm-ID: 187711 Cd Length: 134 Bit Score: 46.62 E-value: 3.87e-06
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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