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Concise Results
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MULTISPECIES: peptidoglycan glycosyltransferase FtsI [Enterobacter]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
PRK15105 super family
cl33083 peptidoglycan synthase FtsI; Provisional
11-564
0e+00
peptidoglycan synthase FtsI; Provisional
PRK15105 :Pssm-ID: 185060 [Multi-domain]
Cd Length: 578
Bit Score: 876.46
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 11 NF TPA RF V LLC LA I FCS L A FLLGRVAWLQ I I K PD N LV KQE DMRSLR QLAIDAP RGMI M DR E GRPLAVSVPV R A V WADPK T 90
Cdd:PRK15105 17 NF ISW RF A LLC GC I LLA L V FLLGRVAWLQ V I N PD M LV REG DMRSLR VQEVSTS RGMI T DR S GRPLAVSVPV K A I WADPK E 96
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 91 V LAK GG VGI D E RW Q ALA N AL HLS L GT LSARINANP Q GRFIYLARQV D P AQ A KW I D KL N LPGI N LR D ESRR F YP A G H V A A N 170
Cdd:PRK15105 97 V HDA GG ISV D D RW K ALA D AL NIP L DQ LSARINANP K GRFIYLARQV N P DM A DY I K KL K LPGI H LR E ESRR Y YP S G E V T A H 176
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 171 LIGFTN I D G QGIEGVEKSF NAQ LTG KA G V R Q VR E DRYGRV V E NLTEVAPAP AHN IQ LSIDERLQ TITEDA L D NAVA W NKA 250
Cdd:PRK15105 177 LIGFTN V D S QGIEGVEKSF DKW LTG QP G E R I VR K DRYGRV I E DISSTDSQA AHN LA LSIDERLQ ALVYRE L N NAVA F NKA 256
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 251 ESG AS VL INIP TGE I LAMA SY P DF NPNN RE G ATINDF RNRAI S D T FEPGSTVKP L V L MTALQ Q G L V QPD SV ID T H PY TLD 330
Cdd:PRK15105 257 ESG SA VL VDVN TGE V LAMA NS P SY NPNN LS G TPKDAM RNRAI T D V FEPGSTVKP M V V MTALQ R G V V KEN SV LN T V PY RIN 336
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 331 GH R I R DV GY Y P ELT M TG I LQKSS DT GVS R L S LAMP VQH L I DTY RN FG F G TN T G LGL T GE SA GL L P NRKY WS QLD RATF A F 410
Cdd:PRK15105 337 GH E I K DV AR Y S ELT L TG V LQKSS NV GVS K L A LAMP SSA L V DTY SR FG L G KA T N LGL V GE RS GL Y P QKQR WS DIE RATF S F 416
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 411 GYGLMVTPLQLA H VYATIG GF G LE RPLSIT RI DPPV I G H RV M PE E I AHE V E HMMESVALPGGGGVKAA VRD YR V A V KTGT 490
Cdd:PRK15105 417 GYGLMVTPLQLA R VYATIG SY G IY RPLSIT KV DPPV P G E RV F PE S I VRT V V HMMESVALPGGGGVKAA IKG YR I A I KTGT 496
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 779870254 491 AKK IDDS G K Y VD KY V AYTAGVAPAS D PRFALVVVINDPQ N G A YYGGAVSAPVF SE IMG N VLR LE N VK PD G LP A G 564
Cdd:PRK15105 497 AKK VGPD G R Y IN KY I AYTAGVAPAS Q PRFALVVVINDPQ A G K YYGGAVSAPVF GA IMG G VLR TM N IE PD A LP T G 570
Name
Accession
Description
Interval
E-value
PRK15105
PRK15105 peptidoglycan synthase FtsI; Provisional
11-564
0e+00
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain]
Cd Length: 578
Bit Score: 876.46
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 11 NF TPA RF V LLC LA I FCS L A FLLGRVAWLQ I I K PD N LV KQE DMRSLR QLAIDAP RGMI M DR E GRPLAVSVPV R A V WADPK T 90
Cdd:PRK15105 17 NF ISW RF A LLC GC I LLA L V FLLGRVAWLQ V I N PD M LV REG DMRSLR VQEVSTS RGMI T DR S GRPLAVSVPV K A I WADPK E 96
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 91 V LAK GG VGI D E RW Q ALA N AL HLS L GT LSARINANP Q GRFIYLARQV D P AQ A KW I D KL N LPGI N LR D ESRR F YP A G H V A A N 170
Cdd:PRK15105 97 V HDA GG ISV D D RW K ALA D AL NIP L DQ LSARINANP K GRFIYLARQV N P DM A DY I K KL K LPGI H LR E ESRR Y YP S G E V T A H 176
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 171 LIGFTN I D G QGIEGVEKSF NAQ LTG KA G V R Q VR E DRYGRV V E NLTEVAPAP AHN IQ LSIDERLQ TITEDA L D NAVA W NKA 250
Cdd:PRK15105 177 LIGFTN V D S QGIEGVEKSF DKW LTG QP G E R I VR K DRYGRV I E DISSTDSQA AHN LA LSIDERLQ ALVYRE L N NAVA F NKA 256
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 251 ESG AS VL INIP TGE I LAMA SY P DF NPNN RE G ATINDF RNRAI S D T FEPGSTVKP L V L MTALQ Q G L V QPD SV ID T H PY TLD 330
Cdd:PRK15105 257 ESG SA VL VDVN TGE V LAMA NS P SY NPNN LS G TPKDAM RNRAI T D V FEPGSTVKP M V V MTALQ R G V V KEN SV LN T V PY RIN 336
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 331 GH R I R DV GY Y P ELT M TG I LQKSS DT GVS R L S LAMP VQH L I DTY RN FG F G TN T G LGL T GE SA GL L P NRKY WS QLD RATF A F 410
Cdd:PRK15105 337 GH E I K DV AR Y S ELT L TG V LQKSS NV GVS K L A LAMP SSA L V DTY SR FG L G KA T N LGL V GE RS GL Y P QKQR WS DIE RATF S F 416
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 411 GYGLMVTPLQLA H VYATIG GF G LE RPLSIT RI DPPV I G H RV M PE E I AHE V E HMMESVALPGGGGVKAA VRD YR V A V KTGT 490
Cdd:PRK15105 417 GYGLMVTPLQLA R VYATIG SY G IY RPLSIT KV DPPV P G E RV F PE S I VRT V V HMMESVALPGGGGVKAA IKG YR I A I KTGT 496
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 779870254 491 AKK IDDS G K Y VD KY V AYTAGVAPAS D PRFALVVVINDPQ N G A YYGGAVSAPVF SE IMG N VLR LE N VK PD G LP A G 564
Cdd:PRK15105 497 AKK VGPD G R Y IN KY I AYTAGVAPAS Q PRFALVVVINDPQ A G K YYGGAVSAPVF GA IMG G VLR TM N IE PD A LP T G 570
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
1-555
0e+00
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 606.44
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 1 MK K K LIT tag NFTPA R FV LL C L AIFCSLAF L L GR VAW LQ IIKP D NLVKQEDMRSL R QLA I D APRG M I M DR E G RP LA VS VP 80
Cdd:COG0768 1 MK R K KEK --- RLFRR R LL LL F L LVLLLFLL L V GR LFY LQ VVEG D EYAELAEENRI R TVP I P APRG L I Y DR N G NV LA TN VP 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 81 V RAVW ADP KT V LAK ggvgi D E RWQA LA NA L H L SLGT L SARINAN p QGRFI YL A R QVD P AQ A KW I DK L N LPG INLRD E SR R 160
Cdd:COG0768 78 V YSLY ADP EE V KDP ----- E E TAEK LA KL L G L DPEE L RKKLKKK - SRFPV YL K R NLS P EE A AR I RA L K LPG VYVEA E YK R 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 161 F YP A G HV AA NLI G FTNI ---- DG Q G IE G V EK SFNAQ L T G KA G V R Q V RE D RY GRV VEN L - T E VA P A P AHNIQ L S ID ER LQ T 235
Cdd:COG0768 152 Y YP Y G EL AA HVL G YVGE ingg DG I G KS G L EK AYEDL L R G TP G K R R V EV D AR GRV IRD L g E E KP P V P GKDLV L T ID SD LQ K 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 236 I T E D AL DN AV AWN KA E SGA S V LINIP TGEILAMASYP D F N PN NRE G ATINDF RNRA ISD T F EPGST V KP LVLMT AL QQ G L 315
Cdd:COG0768 232 I A E E AL KK AV EEY KA K SGA V V VMDPK TGEILAMASYP S F D PN LFV G GPDEPL RNRA VQG T Y EPGST F KP FTAAA AL EE G V 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 316 VQ PD SVI - DTHP Y TLD G HR IRD -- V G YYPE LT M T GI L Q KSS DT G VSR L S L AMPVQH L I D TYRN FG F G TN TG LG L T GE SA G 392
Cdd:COG0768 312 IT PD TTF d CPGY Y RVG G RT IRD wd R G GHGT LT L T EA L A KSS NV G FYK L A L RLGIDK L Y D YLKK FG L G QK TG ID L P GE AS G 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 393 LLP NR K Y W SQLDR AT FAF G Y GL M VTPLQLA HV YA T I -- GG F -------- GLER P LSITRIDP P VIGH RV MPE E I A HE V EH 462
Cdd:COG0768 392 LLP SP K R W YPGET AT MSI G Q GL S VTPLQLA QA YA A I an GG V lvkphlvk EIVD P DGEVVKEE P EVLR RV ISP E T A ET V RE 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 463 M ME S V AL - PGG GGVK AA VRD YRVA V KTGTA KKI D -- DS G K Y VDKYV A YTA G V APA SD PR F A LV VV IND P Q n G AY YGG A V S 539
Cdd:COG0768 472 G ME G V VN e PGG TARR AA IPG YRVA G KTGTA QVV D ig NG G Y Y KGRHI A SFV G F APA DN PR Y A VA VV VEN P G - G GA YGG T V A 550
570
....*....|....*.
gi 779870254 540 APVF S EIM GNV LRL EN 555
Cdd:COG0768 551 APVF R EIM EAY LRL LG 566
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
16-547
2.99e-95
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 302.52
E-value: 2.99e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 16 R FVL L CLAIFCSLAF L LG R VAW LQ I I KPDNLVKQEDMRSL R QLA I DA PRG M I M DR E G RP LA VSV P VRAVWA ------ D PK 89
Cdd:TIGR03423 2 R ALV L GGLVLALFGV L AA R LFY LQ V I RGEEYATLSEDNRI R LVP I PP PRG L I L DR N G VL LA DNR P SFSLEI vpekvd D LD 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 90 TV L AK ggvgiderwqa LA NA L H L SLGTL s AR INANP -- QG RF -- I Y L ARQVDPAQAKWI -- DKLN LPG INLRDESR R F YP 163
Cdd:TIGR03423 82 AT L DR ----------- LA KL L D L DPEDI - AR FLKEL kr SR RF ep I P L KSDLTEEEVARF av NQYR LPG VEIEARLK R Y YP 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 164 A G HV AA NLI G FTN - I DGQGI E ---------------- G V EK SFNAQ L T GK A G V R Q V REDRY GRV VEN L TE V A P A P AHNIQ 226
Cdd:TIGR03423 150 Y G EL AA HVL G YVG e I NEEDL E rlepanyaggdyigks G I EK YYEDE L R GK P G Y R E V EVNAR GRV IRT L SR V P P V P GKDLV 229
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 227 L S ID E RLQ TIT E D AL DN avawnka ES GA S V LINIP TGEILAM A S Y P D F N PN ------- NREGATIND ----- FR NRAI SD 294
Cdd:TIGR03423 230 L T ID A RLQ QAA E K AL GG ------- RR GA V V VMDPR TGEILAM V S T P S F D PN lfvdgis SKDYKALLN dpdrp LL NRAI QG 302
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 295 TFE PGST V KP L V LMT AL QQ G LVQ P DSV I - DTHPYT L D G H R I R D ----- V G Y ype LTMTGILQK S S D TGVSR L S L AMPVQH 368
Cdd:TIGR03423 303 VYP PGST F KP V V ALA AL EE G VIT P ETR I y CPGYFQ L G G R R F R C wkrgg H G R --- VDLRKAIEE S C D VYFYQ L A L RLGIDK 379
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 369 LIDTYRN FGFG TN TG LG L T GE SA GL L P N R KY -------- W SQL D RATFAF G Y G LM - VTPLQLA HVY A TIGGF G - L ER P -- 436
Cdd:TIGR03423 380 IAEYAKR FGFG QK TG ID L P GE KS GL V P S R EW krkrfgqp W YPG D TLNVSI G Q G YV l VTPLQLA VAT A ALANG G k L YK P hl 459
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 437 --------- LSIT R ID P P V IGHRVMPE E IAHE V EHM M ES V A - L PGG GGVK A AV - RD Y RV A V KTGTA -- KKIDDSG KY VDK 503
Cdd:TIGR03423 460 vksiedpdg GVVR R TE P E V LRPLPISP E NLDV V REG M RD V V n G PGG TARR A RL g LP Y KM A G KTGTA qv VSLKQGE KY DAE 539
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 779870254 504 YVAYT ------- AGV AP ASD P RF A LV V VI ndp QN G A y Y G GAVS AP VFSE IM 547
Cdd:TIGR03423 540 QIPER lrdhalf VAF AP YDN P KI A VA V IV --- EH G G - G G SSAA AP IARK IM 586
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
253-547
3.35e-86
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 269.29
E-value: 3.35e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 253 G AS V LINIP TGE I LAM ASY P DFN PN NR egat I NDF RNRA ISDTF EPGST V KP LVLMT AL QQ G LVQ PD SV I DTH P YTL - D G 331
Cdd:pfam00905 1 G SA V VLDPK TGE V LAM VGK P SYD PN GF ---- I GPL RNRA VTSRY EPGST F KP FTALA AL DN G VLK PD ET I FDW P GKQ q G G 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 332 HR I R D -- VGYYPEL T MTGI L QK SS DTGVSR L SLAMPVQH L IDTYRN FG F G TN TG L GL T GE S AG L L PN rk YW sq L DR AT FA 409
Cdd:pfam00905 77 KS I G D wn QDQVGIG T LRQA L EY SS NWYMQK L AQKLGADK L RSYLKK FG Y G NK TG I GL P GE N AG Y L TP -- YW -- L EG AT AS 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 410 FG Y GL MV TPLQ L A HV YA T I GGF G LER P LSIT ----- RI DP P V IGHRVMPEEI A HE V EH M MES V ALP G G G GVK AAV RD Y R V 484
Cdd:pfam00905 153 FG I GL TI TPLQ Q A QA YA A I ANG G KLV P PHLV ksied KV DP K V LNKLPISKST A EK V KD M LRL V VND G T G TGT AAV PG Y K V 232
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 779870254 485 A V KTGTA KKI -- DDS G K Y VDKYVAYTA G V APA SD P RF A LV V V I N DP QN ga YYGG A V S AP V F SE I M 547
Cdd:pfam00905 233 A G KTGTA QVA gp KGG G Y Y DGAQIGWFV G Y APA DN P KY A FA V L I D DP KR -- YYGG K V A AP I F KD I L 295
Name
Accession
Description
Interval
E-value
PRK15105
PRK15105 peptidoglycan synthase FtsI; Provisional
11-564
0e+00
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain]
Cd Length: 578
Bit Score: 876.46
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 11 NF TPA RF V LLC LA I FCS L A FLLGRVAWLQ I I K PD N LV KQE DMRSLR QLAIDAP RGMI M DR E GRPLAVSVPV R A V WADPK T 90
Cdd:PRK15105 17 NF ISW RF A LLC GC I LLA L V FLLGRVAWLQ V I N PD M LV REG DMRSLR VQEVSTS RGMI T DR S GRPLAVSVPV K A I WADPK E 96
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 91 V LAK GG VGI D E RW Q ALA N AL HLS L GT LSARINANP Q GRFIYLARQV D P AQ A KW I D KL N LPGI N LR D ESRR F YP A G H V A A N 170
Cdd:PRK15105 97 V HDA GG ISV D D RW K ALA D AL NIP L DQ LSARINANP K GRFIYLARQV N P DM A DY I K KL K LPGI H LR E ESRR Y YP S G E V T A H 176
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 171 LIGFTN I D G QGIEGVEKSF NAQ LTG KA G V R Q VR E DRYGRV V E NLTEVAPAP AHN IQ LSIDERLQ TITEDA L D NAVA W NKA 250
Cdd:PRK15105 177 LIGFTN V D S QGIEGVEKSF DKW LTG QP G E R I VR K DRYGRV I E DISSTDSQA AHN LA LSIDERLQ ALVYRE L N NAVA F NKA 256
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 251 ESG AS VL INIP TGE I LAMA SY P DF NPNN RE G ATINDF RNRAI S D T FEPGSTVKP L V L MTALQ Q G L V QPD SV ID T H PY TLD 330
Cdd:PRK15105 257 ESG SA VL VDVN TGE V LAMA NS P SY NPNN LS G TPKDAM RNRAI T D V FEPGSTVKP M V V MTALQ R G V V KEN SV LN T V PY RIN 336
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 331 GH R I R DV GY Y P ELT M TG I LQKSS DT GVS R L S LAMP VQH L I DTY RN FG F G TN T G LGL T GE SA GL L P NRKY WS QLD RATF A F 410
Cdd:PRK15105 337 GH E I K DV AR Y S ELT L TG V LQKSS NV GVS K L A LAMP SSA L V DTY SR FG L G KA T N LGL V GE RS GL Y P QKQR WS DIE RATF S F 416
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 411 GYGLMVTPLQLA H VYATIG GF G LE RPLSIT RI DPPV I G H RV M PE E I AHE V E HMMESVALPGGGGVKAA VRD YR V A V KTGT 490
Cdd:PRK15105 417 GYGLMVTPLQLA R VYATIG SY G IY RPLSIT KV DPPV P G E RV F PE S I VRT V V HMMESVALPGGGGVKAA IKG YR I A I KTGT 496
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 779870254 491 AKK IDDS G K Y VD KY V AYTAGVAPAS D PRFALVVVINDPQ N G A YYGGAVSAPVF SE IMG N VLR LE N VK PD G LP A G 564
Cdd:PRK15105 497 AKK VGPD G R Y IN KY I AYTAGVAPAS Q PRFALVVVINDPQ A G K YYGGAVSAPVF GA IMG G VLR TM N IE PD A LP T G 570
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
1-555
0e+00
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 606.44
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 1 MK K K LIT tag NFTPA R FV LL C L AIFCSLAF L L GR VAW LQ IIKP D NLVKQEDMRSL R QLA I D APRG M I M DR E G RP LA VS VP 80
Cdd:COG0768 1 MK R K KEK --- RLFRR R LL LL F L LVLLLFLL L V GR LFY LQ VVEG D EYAELAEENRI R TVP I P APRG L I Y DR N G NV LA TN VP 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 81 V RAVW ADP KT V LAK ggvgi D E RWQA LA NA L H L SLGT L SARINAN p QGRFI YL A R QVD P AQ A KW I DK L N LPG INLRD E SR R 160
Cdd:COG0768 78 V YSLY ADP EE V KDP ----- E E TAEK LA KL L G L DPEE L RKKLKKK - SRFPV YL K R NLS P EE A AR I RA L K LPG VYVEA E YK R 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 161 F YP A G HV AA NLI G FTNI ---- DG Q G IE G V EK SFNAQ L T G KA G V R Q V RE D RY GRV VEN L - T E VA P A P AHNIQ L S ID ER LQ T 235
Cdd:COG0768 152 Y YP Y G EL AA HVL G YVGE ingg DG I G KS G L EK AYEDL L R G TP G K R R V EV D AR GRV IRD L g E E KP P V P GKDLV L T ID SD LQ K 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 236 I T E D AL DN AV AWN KA E SGA S V LINIP TGEILAMASYP D F N PN NRE G ATINDF RNRA ISD T F EPGST V KP LVLMT AL QQ G L 315
Cdd:COG0768 232 I A E E AL KK AV EEY KA K SGA V V VMDPK TGEILAMASYP S F D PN LFV G GPDEPL RNRA VQG T Y EPGST F KP FTAAA AL EE G V 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 316 VQ PD SVI - DTHP Y TLD G HR IRD -- V G YYPE LT M T GI L Q KSS DT G VSR L S L AMPVQH L I D TYRN FG F G TN TG LG L T GE SA G 392
Cdd:COG0768 312 IT PD TTF d CPGY Y RVG G RT IRD wd R G GHGT LT L T EA L A KSS NV G FYK L A L RLGIDK L Y D YLKK FG L G QK TG ID L P GE AS G 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 393 LLP NR K Y W SQLDR AT FAF G Y GL M VTPLQLA HV YA T I -- GG F -------- GLER P LSITRIDP P VIGH RV MPE E I A HE V EH 462
Cdd:COG0768 392 LLP SP K R W YPGET AT MSI G Q GL S VTPLQLA QA YA A I an GG V lvkphlvk EIVD P DGEVVKEE P EVLR RV ISP E T A ET V RE 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 463 M ME S V AL - PGG GGVK AA VRD YRVA V KTGTA KKI D -- DS G K Y VDKYV A YTA G V APA SD PR F A LV VV IND P Q n G AY YGG A V S 539
Cdd:COG0768 472 G ME G V VN e PGG TARR AA IPG YRVA G KTGTA QVV D ig NG G Y Y KGRHI A SFV G F APA DN PR Y A VA VV VEN P G - G GA YGG T V A 550
570
....*....|....*.
gi 779870254 540 APVF S EIM GNV LRL EN 555
Cdd:COG0768 551 APVF R EIM EAY LRL LG 566
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
16-547
2.99e-95
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 302.52
E-value: 2.99e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 16 R FVL L CLAIFCSLAF L LG R VAW LQ I I KPDNLVKQEDMRSL R QLA I DA PRG M I M DR E G RP LA VSV P VRAVWA ------ D PK 89
Cdd:TIGR03423 2 R ALV L GGLVLALFGV L AA R LFY LQ V I RGEEYATLSEDNRI R LVP I PP PRG L I L DR N G VL LA DNR P SFSLEI vpekvd D LD 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 90 TV L AK ggvgiderwqa LA NA L H L SLGTL s AR INANP -- QG RF -- I Y L ARQVDPAQAKWI -- DKLN LPG INLRDESR R F YP 163
Cdd:TIGR03423 82 AT L DR ----------- LA KL L D L DPEDI - AR FLKEL kr SR RF ep I P L KSDLTEEEVARF av NQYR LPG VEIEARLK R Y YP 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 164 A G HV AA NLI G FTN - I DGQGI E ---------------- G V EK SFNAQ L T GK A G V R Q V REDRY GRV VEN L TE V A P A P AHNIQ 226
Cdd:TIGR03423 150 Y G EL AA HVL G YVG e I NEEDL E rlepanyaggdyigks G I EK YYEDE L R GK P G Y R E V EVNAR GRV IRT L SR V P P V P GKDLV 229
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 227 L S ID E RLQ TIT E D AL DN avawnka ES GA S V LINIP TGEILAM A S Y P D F N PN ------- NREGATIND ----- FR NRAI SD 294
Cdd:TIGR03423 230 L T ID A RLQ QAA E K AL GG ------- RR GA V V VMDPR TGEILAM V S T P S F D PN lfvdgis SKDYKALLN dpdrp LL NRAI QG 302
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 295 TFE PGST V KP L V LMT AL QQ G LVQ P DSV I - DTHPYT L D G H R I R D ----- V G Y ype LTMTGILQK S S D TGVSR L S L AMPVQH 368
Cdd:TIGR03423 303 VYP PGST F KP V V ALA AL EE G VIT P ETR I y CPGYFQ L G G R R F R C wkrgg H G R --- VDLRKAIEE S C D VYFYQ L A L RLGIDK 379
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 369 LIDTYRN FGFG TN TG LG L T GE SA GL L P N R KY -------- W SQL D RATFAF G Y G LM - VTPLQLA HVY A TIGGF G - L ER P -- 436
Cdd:TIGR03423 380 IAEYAKR FGFG QK TG ID L P GE KS GL V P S R EW krkrfgqp W YPG D TLNVSI G Q G YV l VTPLQLA VAT A ALANG G k L YK P hl 459
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 437 --------- LSIT R ID P P V IGHRVMPE E IAHE V EHM M ES V A - L PGG GGVK A AV - RD Y RV A V KTGTA -- KKIDDSG KY VDK 503
Cdd:TIGR03423 460 vksiedpdg GVVR R TE P E V LRPLPISP E NLDV V REG M RD V V n G PGG TARR A RL g LP Y KM A G KTGTA qv VSLKQGE KY DAE 539
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 779870254 504 YVAYT ------- AGV AP ASD P RF A LV V VI ndp QN G A y Y G GAVS AP VFSE IM 547
Cdd:TIGR03423 540 QIPER lrdhalf VAF AP YDN P KI A VA V IV --- EH G G - G G SSAA AP IARK IM 586
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
253-547
3.35e-86
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 269.29
E-value: 3.35e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 253 G AS V LINIP TGE I LAM ASY P DFN PN NR egat I NDF RNRA ISDTF EPGST V KP LVLMT AL QQ G LVQ PD SV I DTH P YTL - D G 331
Cdd:pfam00905 1 G SA V VLDPK TGE V LAM VGK P SYD PN GF ---- I GPL RNRA VTSRY EPGST F KP FTALA AL DN G VLK PD ET I FDW P GKQ q G G 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 332 HR I R D -- VGYYPEL T MTGI L QK SS DTGVSR L SLAMPVQH L IDTYRN FG F G TN TG L GL T GE S AG L L PN rk YW sq L DR AT FA 409
Cdd:pfam00905 77 KS I G D wn QDQVGIG T LRQA L EY SS NWYMQK L AQKLGADK L RSYLKK FG Y G NK TG I GL P GE N AG Y L TP -- YW -- L EG AT AS 152
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 410 FG Y GL MV TPLQ L A HV YA T I GGF G LER P LSIT ----- RI DP P V IGHRVMPEEI A HE V EH M MES V ALP G G G GVK AAV RD Y R V 484
Cdd:pfam00905 153 FG I GL TI TPLQ Q A QA YA A I ANG G KLV P PHLV ksied KV DP K V LNKLPISKST A EK V KD M LRL V VND G T G TGT AAV PG Y K V 232
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 779870254 485 A V KTGTA KKI -- DDS G K Y VDKYVAYTA G V APA SD P RF A LV V V I N DP QN ga YYGG A V S AP V F SE I M 547
Cdd:pfam00905 233 A G KTGTA QVA gp KGG G Y Y DGAQIGWFV G Y APA DN P KY A FA V L I D DP KR -- YYGG K V A AP I F KD I L 295
PRK10795
PRK10795 penicillin-binding protein 2; Provisional
38-551
2.08e-38
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain]
Cd Length: 634
Bit Score: 149.53
E-value: 2.08e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 38 LQI IKPDNLVKQEDMRSLRQLA I DAP RG M I M DR E G R PLA VSVPVRAVWAD P KT V lakgg VGIDERWQ AL ANALH L SLGTL 117
Cdd:PRK10795 43 LQI VRFTDYQTRSNENRIKLVP I APS RG I I Y DR N G T PLA LNRTIYQLEMM P EK V ----- DNLQQTLD AL RSVVD L TDDDI 117
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 118 S A ---- R INAN pqg RF IYLARQVDPAQAK ---- WIDKLNL PG INLRDES RR F YP A G HVAANL IG FTN --------- I D GQ 180
Cdd:PRK10795 118 A A frke R ARSR --- RF TSIPVKTNLTEVQ varf AVNQYRF PG VEVKGYQ RR Y YP Y G SALTHV IG YVS kindkdver L D KE 194
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 181 G IE ------------ G V E KSFNAQ L T GK A G VRQ V REDRY GRV VEN L T E VA P APA H N I Q L SI D ER LQ TIT E DA L dnavawn 248
Cdd:PRK10795 195 G KL anyaathdigkl G I E RYYEDV L H GK T G YEE V EVNNR GRV IRQ L H E QP P QAG H D I Y L TL D LK LQ QYI E TL L ------- 267
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 249 k A E S G A S V LINI P - TG E ILA MA S Y P DFN PN - NRE G ATIN D FR ----------- NRA ISDTFE P G STVKP L V LMT AL QQ G L 315
Cdd:PRK10795 268 - A G S R A A V VVTD P r TG G ILA LV S T P SYD PN l FVD G ISSK D YS gllndpnrpli NRA TQGVYP P A STVKP Y V AVS AL SA G V 346
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 316 VQPD - S VI D THPYT L D G -- H R I RD VGYY -- PE L TM T GI L QK S S DT GVSRLSLA M PVQH L IDTYRN FG F G TN TG LG L TG E S 390
Cdd:PRK10795 347 ITRN t S LF D PGWWQ L P G se K R Y RD WKKW gh GR L NV T KS L EE S A DT FFYQVAYD M GIDR L SEWMGK FG Y G HY TG ID L AE E R 426
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 391 A G LL P N R -------- K Y W S Q L D RATFAF G Y G L - MV TP L Q LAHVYA T IGGF G - LER P -- L SI T RI D PPVIGHRVMP E ---- 454
Cdd:PRK10795 427 S G NM P T R ewkqkrfk K P W Y Q G D TIPVGI G Q G Y w TA TP I Q MSKALM T LIND G i VKV P hl L MS T AE D GKQVPWVQPH E ppvg 506
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 455 ------- EIA HE veh M M ES VA - L P G G GGV K A - A VRD Y RV A V K T GTA KKI dd SG K YVDK Y V A YT ----------- AGV AP A 514
Cdd:PRK10795 507 dihsgyw EIA KD --- G M YG VA n R P N G TAH K Y f A SAP Y KI A A K S GTA QVF -- GL K ANET Y N A HK iaerlrdhklm TAF AP Y 581
570 580 590
....*....|....*....|....*....|....*..
gi 779870254 515 SD P RF A LVVVIND pqngayy GGA vs A P VFSE IM GNV L 551
Cdd:PRK10795 582 NN P QV A VAIILEN ------- GGA -- G P AVGT IM RQI L 609
MrcB
COG0744 Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
225-564
2.48e-37
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain]
Cd Length: 630
Bit Score: 146.60
E-value: 2.48e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 225 I QLSI D ER LQ TIT E D A LD N AVAWN K AES -- G A S V LINIP TGE I LAM ASYP D FNPNNR egatindfr NRA ISDTFE PGST V 302
Cdd:COG0744 297 I YTTL D PK LQ KAA E K A VK N VLPEG K PGG lq A A L V VVDPK TGE V LAM VGGR D YGKSQF --------- NRA TQAKRQ PGST F 367
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 303 KP L V LMT AL Q QG L v Q P DSVI D TH P Y T LD G -- HRIR -- D VG Y YPEL T MTGI L QK S SD T GVS RL SLAMPVQHLI DT Y R NF G F 378
Cdd:COG0744 368 KP F V YAA AL E QG Y - T P ATTV D DE P V T FP G gg WSPK ny D GR Y RGPV T LREA L AN S LN T PAV RL AQEVGLDKVV DT A R RL G I 446
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 379 GTNTGLGL tgesagllpnrkywsqldra TF A F G - YG lm V T PL QL A HV YAT I -- GG FGL E r P LS IT RI --------- DPPV 446
Cdd:COG0744 447 TSPLDPNP -------------------- SL A L G t SE -- V S PL EM A SA YAT F an GG VYV E - P HA IT KV tdadgkvly EAKP 503
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 447 IGHR V MPE E I A HEVEH M MES V a LPG G G G VK A AVRDYR VA V KTGT AKKID D SG kyvdk Y V A YT agvapasd P RFALV V VIN 526
Cdd:COG0744 504 KCEQ V ISP E V A YLMTD M LQD V - VTS G T G RA A RLPGRP VA G KTGT TNDNR D AW ----- F V G YT -------- P QLVTA V WVG 569
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 779870254 527 DPQ N --- G AYY GG AVS AP VFSEI M GNV L RLEN V KPDGL P A G 564
Cdd:COG0744 570 NDD N spm G YVT GG SLP AP IWRDF M EAA L EGLP V EDFPK P S G 610
PBP_dimer
pfam03717 Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of ...
59-213
4.71e-24
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly implicated in PBP polymerization. The domain forms a largely disordered 'sugar tongs' structure.
Pssm-ID: 427460 [Multi-domain]
Cd Length: 178
Bit Score: 99.32
E-value: 4.71e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 59 A I D APRG M I M DR E G RP LA VSV PV RAVWAD P - K TVL A KGGVGIDERWQA L A N ALH L SLGT L SA R INANPQGR --- FIYLAR 134
Cdd:pfam03717 1 P I P APRG E I Y DR N G VV LA TNK PV YSLTIT P s K LKK A DALKTALKLAKL L S N YED L DDED L TE R FLKMNSYK syy PVVIKK 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 135 QVDPAQAKW I DK -- L N LPG INLRDESR R F YP A G HV AA N L I G FT ----------------- NI D GQ G IE G V EK SFNAQ L T G 195
Cdd:pfam03717 81 NLSEEEVAR I EE nl L E LPG VSIETDPV R Y YP Y G EL AA H L L G YV geiteeelekyldkgys RG D LV G KS G L EK QYESV L R G 160
170
....*....|....*...
gi 779870254 196 K A GVRQV RE D RY GRV VEN 213
Cdd:pfam03717 161 K D GVRQV EV D AL GRV IRE 178
PbpC
COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ...
225-566
3.55e-21
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain]
Cd Length: 773
Bit Score: 97.98
E-value: 3.55e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 225 I QLSI D ER LQ TIT E DALDNA V A --- W N KAESG A SVLINIP TGE I LA MASYP DF NPNN R E G A ti N D F r N RA I - S dtfe PGS 300
Cdd:COG4953 274 I RTTL D AG LQ RRL E RLVRRY V R rlk Q N GIHNA A VLVVDNR TGE V LA YVGSA DF FDAS R Q G Q -- V D M - V RA L r S ---- PGS 346
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 301 T V KP LVLMT AL Q QGL VQ P DSVIDTH P YTLD G H R IR -- D VGYYPELTMTGI L Q kssdtgvsr L SL AM P VQH L IDTY ----- 373
Cdd:COG4953 347 T L KP FLYGL AL D QGL IH P ETLLADV P TSFG G Y R PE nf D GTFQGPVSAREA L A --------- R SL NI P AVR L LEAL gparf 417
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 374 ---- R NF G FGT ntglgltgesag LLP NRKY wsqldratfafg YGL M ------- VT PLQ L AHV YA TIGGF G LE RPL SITRI 442
Cdd:COG4953 418 yarl R RA G LRL ------------ LLP PAEH ------------ YGL S lilggae VT LEE L VGL YA ALARG G EA RPL RLLAG 473
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 779870254 443 D P PVI G H R VMPEEI A HE V EHMMES V AL P G G - G G VK A AVRDYRV A V KTGT akkidd S GKYV D kyv A YTA G V apas DP R FAL 521
Cdd:COG4953 474 E P ASP G R R LLSPGA A WL V RDILSD V PR P D G a F G WR A LDSPPPI A W KTGT ------ S YGFR D --- A WAV G F ---- TG R YTV 540
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 779870254 522 V V VI ---- ND P QN G A y Y G GAVS AP VFSE I MG --------------- NV LR L E NVK P D GL P AG SD 566
Cdd:COG4953 541 G V WV gnpd GT P VP G L - T G AEAA AP LLFD I FD llpasrwplpfpppa GL LR V E VCA P S GL L AG PN 603
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
