|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13564 |
PRK13564 |
anthranilate synthase component 1; |
6-510 |
0e+00 |
|
anthranilate synthase component 1;
Pssm-ID: 237428 [Multi-domain] Cd Length: 520 Bit Score: 923.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 6 TRLPLGEFDTIRLNAPYVTDPLALYTRLCQDRPNNLLLESVEIDSKAGTQSLLLVDACLRIECRGRAVQVRPLGDNGAAL 85
Cdd:PRK13564 1 MQTQKPTLELLTCKAPYREDPTALFHQLCGDRPATLLLESAEIDSKDNLKSLLLVDSALRITCLGNTVTIQALTDNGAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 86 LRLLEQRLPAVITQTRVADELHLDFPASDRELDEDSRLKGSSVLDVLRTLQRELQC-QQGKEALFMAGSFAYDLIASFED 164
Cdd:PRK13564 81 LPLLDEALPAGVENEQDPNGLVLTFPPVSPLLDEDARLKSLSVFDALRLLQKLVNTpKEEREALFLGGLFAYDLVAGFEP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 165 LPEVPEGsNDCPDYCFYVAETLITIDHIKQSTQLVACLFGGEEDEqldarYARLTARLESFKQACQQPLPAPQGTAPLTG 244
Cdd:PRK13564 161 LPQLPAG-NNCPDYCFYLAETLLVIDHQKKSARLQASLFTPDEEE-----KQRLAARLAQLKQQLTQPAPPLPVTSVPDM 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 245 ALAVDKGDKQFCAEVEKLKGFIRRGDIFQVVPSRSFSLPCPDPVAAYRRLKQTNPSPYMFYVQDEGFTLFGASPESAVKF 324
Cdd:PRK13564 235 EVSVNISDEEFCAVVRKLKEHIRAGDIFQVVPSRRFSLPCPSPLAAYRVLKKSNPSPYMFYMQDEDFTLFGASPESALKY 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 325 CANSRQVEMYPIAGTRRRGLNPDGSINLDLDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYS 404
Cdd:PRK13564 315 DASSRQVEIYPIAGTRPRGRRADGSIDRDLDSRIELELRTDHKELAEHLMLVDLARNDLARICQPGSRYVADLLKVDRYS 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 405 HVMHLVSRVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVK 484
Cdd:PRK13564 395 HVMHLVSRVVGELRHDLDALHAYRACMNMGTLTGAPKVRAMQLIREVEGQRRGSYGGAVGYLTGHGDLDTCIVIRSAFVE 474
|
490 500
....*....|....*....|....*.
gi 780220209 485 EGVAHVQAGAGVVYDSKPQAEADETR 510
Cdd:PRK13564 475 NGIATVQAGAGVVLDSDPQSEADETR 500
|
|
| trpE_proteo |
TIGR00565 |
anthranilate synthase component I, proteobacterial subset; This enzyme resembles some other ... |
22-510 |
0e+00 |
|
anthranilate synthase component I, proteobacterial subset; This enzyme resembles some other chorismate-binding enzymes, including para-aminobenzoate synthase (pabB) and isochorismate synthase. There is a fairly deep split between two sets, seen in the pattern of gaps as well as in amino acid sequence differences. This group includes proteobacteria such as E. coli and Helicobacter pylori but also the gram-positive organism Corynebacterium glutamicum. The second group includes eukaryotes, archaea, and most other bacterial lineages; sequences from the second group may resemble pabB more closely than other trpE from this group. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273143 [Multi-domain] Cd Length: 498 Bit Score: 616.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 22 YVTDPLALYTRLCQDRPNNLLLESVEIDSKAGTQSLLLVDACLRIECRGRAVQVRPLGDNGAALLRLLEQRLPAVITQTR 101
Cdd:TIGR00565 1 YIPYPTALFEKLCQSNPHTLLLESAEIESKAHLKSLLLVKAALKITCLGNIVTITALTPNGGAFLQKLSAFLKAPVSAVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 102 VADELHLDFPASDRELDEDSRLKGSSVLDVLRTLQRELQCQQGKEALFMAGSFAYDLIASFEDLPEVPEGSNDCPDYCFY 181
Cdd:TIGR00565 81 QDNALILTFTPNKKTLDEDLKLFSPSPFDALRLFKSLKTKPKHPFTLFSGGLFSYDLVAFFEDLPHLKAKNNNCPDFIFY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 182 VAETLITIDHIKQSTQLVACLFGGEEDEQldaryaRLTARL-ESFKQACQQPLPAPQGTAPlTGALAVDKGDKQFCAEVE 260
Cdd:TIGR00565 161 LAENLIIIDHQEKSVEILGACFAERFETQ------IAQALQdLKELQKSIKSDFVPKKSKQ-SREVSANCSDSEFEGRVL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 261 KLKGFIRRGDIFQVVPSRSFSLPCPDPVAAYRRLKQTNPSPYMFYVQDEGFTLFGASPESAVKFCANSRQVEMYPIAGTR 340
Cdd:TIGR00565 234 SLQEEIKKGEIFQAVPSRRFSLECPEGLAAYYHLKLTNPSPYMFYMKDSDFILFGASPESALKYNALTRQAEIYPIAGTR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 341 RRGLNPDGSINLDLDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRAD 420
Cdd:TIGR00565 314 PRGKDAQGNIDYDLDSRMELELRHDHKERAEHLMLVDLARNDMARVCKSGKRYVAKLLKVDRYSNVMHLVSRVVGELRKG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 421 LDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQAGAGVVYDS 500
Cdd:TIGR00565 394 LDALHAYRACMNMGTLSGAPKISAMQLIYQLENQRRGSYGGAVGYLTSEGSMDTCIVIRSAFVKNGRAVVQAGAGIVLDS 473
|
490
....*....|
gi 780220209 501 KPQAEADETR 510
Cdd:TIGR00565 474 VPQNEADETR 483
|
|
| TrpE |
COG0147 |
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ... |
21-510 |
3.98e-171 |
|
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439917 [Multi-domain] Cd Length: 416 Bit Score: 490.00 E-value: 3.98e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 21 PYVTDPLALYTRLCqDRPNNLLLESVEIDSKAGTQSLLLVDACLRIECRGRAVQVRPLGDngaallrlleqrlpavitqt 100
Cdd:COG0147 10 LALETPVSLFLKLA-DGPYAFLLESAEGGEKWGRYSFIGADPLATLTVRGGRVTIEGGGE-------------------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 101 rvadelhldfpasdreldedSRLKGSSVLDVLRTLQRELQCQQGKEALFMAGS----FAYDLIASFEDLPEVPEGSNDCP 176
Cdd:COG0147 69 --------------------VEPSEGDPLDALRALLARFRLPPLPGLPPFTGGlvgyFGYDLVRYFERLPDLAPDDLGLP 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 177 DYCFYVAETLITIDHIKQSTqlvaclfggeedeqldaryarltarlesfkqacqqplpapqgtapltgalaVDKGDKQFC 256
Cdd:COG0147 129 DAALGLYDRLLVFDHLKGTR---------------------------------------------------SNFTREEYL 157
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 257 AEVEKLKGFIRRGDIFQVVPSRSFSLPCP-DPVAAYRRLKQTNPSPYMFYVQDEGFTLFGASPESAVKFcaNSRQVEMYP 335
Cdd:COG0147 158 AAVERAKEYIRAGDIFQVVLSQRFSAPFEgDPLALYRALRRINPSPYMFYLRFGDFAIVGSSPERLVRV--EDGRVETRP 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 336 IAGTRRRGLNPDgsinldLDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVG 415
Cdd:COG0147 236 IAGTRPRGATPE------EDAALAEELLADEKERAEHLMLVDLARNDLGRVCEPGSVKVPELMVVERYSHVMHLVSTVTG 309
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 416 TLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQAGAG 495
Cdd:COG0147 310 RLRPGLDALDALRATFPAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDGNMDLAIAIRTAVVKDGRAYVQAGAG 389
|
490
....*....|....*
gi 780220209 496 VVYDSKPQAEADETR 510
Cdd:COG0147 390 IVADSDPEAEYQETL 404
|
|
| trpE_most |
TIGR00564 |
anthranilate synthase component I, non-proteobacterial lineages; This enzyme resembles some ... |
26-509 |
5.57e-131 |
|
anthranilate synthase component I, non-proteobacterial lineages; This enzyme resembles some other chorismate-binding enzymes, including para-aminobenzoate synthase (pabB) and isochorismate synthase. There is a fairly deep split between two sets, seen in the pattern of gaps as well as in amino acid sequence differences. Archaeal enzymes have been excluded from this model (and are now found in TIGR01820) as have a clade of enzymes which constitute a TrpE paralog which may have PabB activity (TIGR01824). This allows the B. subtilus paralog which has been shown to have PabB activity to score below trusted to this model. This model contains sequences from gram-positive bacteria, certain proteobacteria, cyanobacteria, plants, fungi and assorted other bacteria.A second family of TrpE enzymes is modelled by TIGR00565. The breaking of the TrpE family into these diverse models allows for the separation of the models for the related enzyme, PabB. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273142 [Multi-domain] Cd Length: 454 Bit Score: 389.39 E-value: 5.57e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 26 PLALYTRLcqDRPNNLLLESVEIDSKAGTQSLLLVDACLRIECRGravqvrplgdnGAALLRLLEQRlpAVITQTRVAD- 104
Cdd:TIGR00564 6 PISAYLKL--AQPGSFLLESAEPGSERGRYSFIGLNPVLTIKTEG-----------GTEYLGADDRR--SGIVGNPLDEi 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 105 ELHLDFPASDRELDEDSRLKGSSVldvlrtlqrelqcqqgkealfmaGSFAYDLIASFEDLPEVPEGSNDCPDYCFYVAE 184
Cdd:TIGR00564 71 RDVMETFAQHSDPELPIPFTGGAV-----------------------GYLGYDTVRLFEKITLPPPDPLNLPDAYLMLCD 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 185 TLITIDHIKQSTQLVACLFGGEEDEQLDARYARLTARLESFKQACQQPLPAPQgTAPLTGALAVDKGDkqFCAEVEKLKG 264
Cdd:TIGR00564 128 DFIIFDHVTDKLYLIHNNRTTASRSAKAAADARLEALVADLQDPLLPEVPVPY-PAALSFTSNYEKEE--YEANVAKAKE 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 265 FIRRGDIFQVVPSRSFSLPCP-DPVAAYRRLKQTNPSPYMFYVQDEGFTLFGASPESAVKfcANSRQVEMYPIAGTRRRG 343
Cdd:TIGR00564 205 YIKAGDIFQVVLSQRFEAKTEaPPFELYRVLRIVNPSPYMYYLDFGDFQIVGSSPELLVK--VTGGRITTRPIAGTRKRG 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 344 LNPDgsinldLDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRADLDA 423
Cdd:TIGR00564 283 ATPE------EDEALAEELLADEKERAEHLMLVDLGRNDIGRVCEPGSVEVPEFMKIERYSHVMHIVSTVEGRLKDGLTA 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 424 LHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQAGAGVVYDSKPQ 503
Cdd:TIGR00564 357 IDALRATFPAGTVSGAPKIRAMELIDELEPEKRGIYGGAVGYLSFDGDMDTAIAIRTMVVKDGKAYVQAGGGIVADSDPE 436
|
....*.
gi 780220209 504 AEADET 509
Cdd:TIGR00564 437 AEYEET 442
|
|
| PRK13571 |
PRK13571 |
anthranilate synthase component I; Provisional |
26-510 |
5.06e-112 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184152 [Multi-domain] Cd Length: 506 Bit Score: 342.39 E-value: 5.06e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 26 PLALYTRLCQDRPNNLLLESVEidskagtqslllvdaclriecrgravqvrplgdNGAALLR--LLEQRLPAVITQtrVA 103
Cdd:PRK13571 36 PVGAYRKLAANRPGTFLLESAE---------------------------------NGRSWSRwsFIGVGSPAALTV--RD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 104 DELH-LDFPASDRELDEDSrlkgssvLDVLRTLQRELQCQQ--GKEALF--MAGSFAYDLIASFEDLPEVPEGSNDCPDY 178
Cdd:PRK13571 81 GEAVwLGTPPAGAPTGGDP-------LAALRATLELLATPRlpGLPPLTggMVGFLGYDAVRRLERLPELAVDDLGLPEM 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 179 CFYVAETLITIDHIKQSTQLVACLFGGEE-DEQLDARYARLTARLESFKQACQQPLPAPQGT-APLTGALAVDKGDKQFC 256
Cdd:PRK13571 154 LLLLATDLAAVDHHEGTITLIANAVNWNGtDERVDAAYDDAVARLDVMTAALAQPLPSTVATfSRPVPEFRAQRTVEEFG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 257 AEVEKLKGFIRRGDIFQVVPSRSFSLPC-PDPVAAYRRLKQTNPSPYMFYVQ------DEGFTLFGASPESAVKfcANSR 329
Cdd:PRK13571 234 AAVEKLVEEIRAGEAFQVVPSQRFEMDTtADPLDVYRVLRVTNPSPYMYLLRvpnsdgGTDFSIVGSSPEALVT--VTDG 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 330 QVEMYPIAGTRRRGLNPDGsinldlDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHL 409
Cdd:PRK13571 312 RATTHPIAGTRWRGATPEE------DALLEKELLADPKERAEHLMLVDLGRNDLGRVCRPGTVRVVDFSHIERYSHVMHL 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 410 VSRVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAH 489
Cdd:PRK13571 386 VSTVTGELAEGRTALDAVTACFPAGTLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDFAGDADTAIAIRTALMRDGTAY 465
|
490 500
....*....|....*....|.
gi 780220209 490 VQAGAGVVYDSKPQAEADETR 510
Cdd:PRK13571 466 VQAGGGVVADSDPDYEDNEAR 486
|
|
| Chorismate_bind |
pfam00425 |
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ... |
253-510 |
5.05e-105 |
|
chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.
Pssm-ID: 425674 [Multi-domain] Cd Length: 255 Bit Score: 315.26 E-value: 5.05e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 253 KQFCAEVEKLKGFIRRGDIFQVVPSRSFSLPCP---DPVAAYRRLKQTNPSPYMFYVQDEGFTLFGASPESAVKFcaNSR 329
Cdd:pfam00425 1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLTLPLAgdiDPLALYRRLRARNPAPYSFYFRTGDFTFLGASPERLLSV--DGG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 330 QVEMYPIAGTRRRGLNPDgsinldLDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHL 409
Cdd:pfam00425 79 RIITEPIAGTRPRGKDPA------EDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 410 VSRVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAH 489
Cdd:pfam00425 153 VSTISGRLKPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRAR 232
|
250 260
....*....|....*....|.
gi 780220209 490 VQAGAGVVYDSKPQAEADETR 510
Cdd:pfam00425 233 LYAGAGIVADSDPEAEWEETE 253
|
|
| TrpE-arch |
TIGR01820 |
anthranilate synthase component I, archaeal clade; This model represents an archaeal clade of ... |
26-509 |
3.24e-103 |
|
anthranilate synthase component I, archaeal clade; This model represents an archaeal clade of anthranilate synthase component I enzymes. This enzyme is responsible for the first step of tryptophan biosynthesis from chorismate. The Sulfolobus enzyme has been reported to be part of a gene cluster for Trp biosynthesis [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273819 [Multi-domain] Cd Length: 435 Bit Score: 317.38 E-value: 3.24e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 26 PLALYTRLCQDRPNNLLLESVEIDSKAGTQSLLLVD--ACLRIECRGRAVQVRPLGDNGAALLRLLEQRLPAVitqtrva 103
Cdd:TIGR01820 1 PLELYKAIRADGDYAFLLESAEKPSKKARYSFIGWDpeFVVRINGKGKSVEGIPEDGDVVDKLRNAFPKLKGI------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 104 delhlDFPASDReldedsRLKGSSVldvlrtlqrelqcqqgkealfmaGSFAYDLIASF-EDLPEVPEGSNDCPDYCFYV 182
Cdd:TIGR01820 74 -----NIPGEDR------RFKGGLV-----------------------GYIAYDAVRDYwEGIVDLKRKAEDWPPAEFFI 119
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 183 AETLITIDHIKQSTQLVaCLFGGEEDEQldaryaRLTARLesfkQACQQPlpapqGTAPLTGALAVDKGDKQFCAEVEKL 262
Cdd:TIGR01820 120 YPNTIVYDHLEGKVYYV-STPEPEAELE------RIVERA----KRATDP-----GEAGVSFEGESLSDREEFEEAVEEA 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 263 KGFIRRGDIFQVVPSRSFSLPCP-DPVAAYRRLKQTNPSPYMFYVQDEGFTLFGASPESAVKfcANSRQVEMYPIAGTRR 341
Cdd:TIGR01820 184 KEYIFAGDIFQVVLSREYEYRLDgDPFELYYNLREINPSPYMFLLKFGDRYLVGSSPETLVR--VEGRTVETNPIAGTRP 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 342 RGLNPDGsinldlDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRADL 421
Cdd:TIGR01820 262 RGATPEE------DERLAKELLSDEKERAEHVMLVDLARNDVRKVSEPGSVKVPEFMYVEKYSHVQHIESTVIGTLKKDY 335
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 422 DALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQAGAGVVYDSK 501
Cdd:TIGR01820 336 DAFDALRATFPAGTLSGAPKIRAMEIIDELEKEPRGVYGGGVGYFSWNGDADFAIAIRTAEIDKDKLRIQAGAGIVADSI 415
|
....*...
gi 780220209 502 PQAEADET 509
Cdd:TIGR01820 416 PEREFEET 423
|
|
| PabB-clade2 |
TIGR01824 |
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely ... |
151-510 |
1.39e-81 |
|
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely related to TrpE (anthranilate synthase, TIGR00564/TIGR01820/TIGR00565) than to the better characterized group of PabB enzymes (TIGR00553/TIGR01823). This clade includes one characterized enzyme from Lactococcus and the conserved function across the clade is supported by these pieces of evidence: 1) all genomes with a member in this clade also have a separate TrpE gene, 2) none of these genomes contain an aparrent PabB from any of the other PabB clades, 3) none of these sequences are found in a region of the genome in association with other Trp biosynthesis genes, 4) all of these genomes aparrently contain most if not all of the steps of the folate biosynthetic pathway (for which PABA is a precursor). Many of the sequences hit by this model are annotated as TrpE enzymes, however, we believe that all members of this clade are, in fact, PabB. The sequences from Bacillus halodurans and subtilus which score below the trusted cutoff for this model are also likely to be PabB enzymes, but are too closely related to TrpE to be separated at this time.
Pssm-ID: 130883 Cd Length: 355 Bit Score: 258.93 E-value: 1.39e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 151 AGSFAYDLIASFEDLPEVPEGSNDCPDYCFYVAETLITIDHIKQstqlvaCLFGGEEDEQLDARYARLTARLESFkqACQ 230
Cdd:TIGR01824 4 LGWLAYDVARRLEGIPDLGTSDGGWPVAADFRYEAAVARDHQRQ------IVALATVPAETEGEFATSSDQLPAV--AAA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 231 QPLPAPQgTAPLTGALAVDKGDKQFCAEVEKLKGFIRRGDIFQVVPSRSFSLPCP---DPVAAYRRLKQTNPSPYMFYVQ 307
Cdd:TIGR01824 76 TSLPSPD-VGPLPVDLEASIDRAAYETGVRRIKDYIRAGDVFQANLSRRLTAPIAadvDPLQLFLALRAPNPAPYAIYLE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 308 DEGFTLFGASPESAVKFCANSRQVEmyPIAGTRRRGLNPDGsinldlDGRIELELRQDEKEVAEHLMLVDLGRNDIARIS 387
Cdd:TIGR01824 155 EPGVDVASASPELFLAREGRVVQTR--PIAGTRPRGATLAE------DGALAAELLQHDKDRAEHVMIVDLERNDLGRVC 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 388 APGTRYVKDLLKVDRYSHVMHLVSRVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLN 467
Cdd:TIGR01824 227 ATGTVRVPELCAVESYSHVHHLVSRVTGRLREGAGLADLIRALFPGGSITGAPKVRAMEIIDELEPQPRGPYTGSVGWID 306
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 780220209 468 GAGEMDTCIVIRSAFVKEGVAHVQAGAGVVYDSKPQAEADETR 510
Cdd:TIGR01824 307 ADGNADLNILIRTLEGGGAQLHFRTGAGIVADSDPAGEWDETE 349
|
|
| PRK13566 |
PRK13566 |
anthranilate synthase component I; |
60-510 |
1.67e-79 |
|
anthranilate synthase component I;
Pssm-ID: 237429 [Multi-domain] Cd Length: 720 Bit Score: 263.70 E-value: 1.67e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 60 VDACLRIECRGRAVQVRPLGDNGAALLRLLEQRL---PAVITQTRVADELHLDFPASDRELDEDSRLKGSSVLDVLRTLQ 136
Cdd:PRK13566 65 VDPPLEITARGRTFTIEALNARGRVLLPFLADTLkalSEVVVLQSTANRIDGTIKEPDAVFTEEERSRQPSVFTVLRALI 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 137 RELQCQqGKEALFMAGSFAYDLIASFEDLPEVPEGSNDCPDYCFYVAETLITIDHIKQSTQLVACLF--GGEEDEQLdar 214
Cdd:PRK13566 145 ALFASE-EDPHLGLYGAFGYDLAFQFEPIEQKLPRPDDQRDLVLYLPDEILVVDHYAARAWVDRYEFavGGVSTEGL--- 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 215 yARLTArlesfKQACQQPLPAPQGTAPLTGALAvdkgdkqfcAEVEKLKGFIRRGDIFQVVPSRSFSLPCPD-PVAAYRR 293
Cdd:PRK13566 221 -PRETA-----PSPYKPTTARPGFADHAPGEYA---------ALVEKAKESFRRGDLFEVVPGQTFYEPCERsPSEIFRR 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 294 LKQTNPSPYMFYVQ-DEGFTLFGASPESAVKfcANSRQVEMYPIAGTRRRGLNPDGsinldlDGRIELELRQDEKEVAEH 372
Cdd:PRK13566 286 LKEINPSPYGFFINlGDGEYLVGASPEMFVR--VEGRRVETCPISGTIKRGADAIG------DAEQIRKLLNSKKDESEL 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 373 LMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVE 452
Cdd:PRK13566 358 TMCTDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHVEGRLRPGFDALDAFLTHAWAVTVTGAPKLWAMQFIEDHE 437
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 780220209 453 GKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQAGAGVVYDSKPQAEADETR 510
Cdd:PRK13566 438 RSPRRWYGGAVGMVGFDGDMNTGLTLRTIRIKDGVAEVRVGATLLFDSDPEAEEAETE 495
|
|
| PRK13572 |
PRK13572 |
anthranilate synthase component I; Provisional |
246-509 |
1.34e-77 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 237432 [Multi-domain] Cd Length: 435 Bit Score: 251.20 E-value: 1.34e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 246 LAVDKGDKQFCAEVEKLKGFIRRGDIFQVVPSRSFSLPCP-DPVAAYRRLKQTNPSPYMFYVQDEGfTLFGASPESAVKF 324
Cdd:PRK13572 166 LGCDADREEFVEMVEKAKEYIYSGDVFQVVLSREYRLKTDlSPFQLYRNLREINPSPYMFLLEFDK-DVVGASPETMASV 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 325 CANSRQVEmyPIAGTRRRGLNPDGsinldlDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYS 404
Cdd:PRK13572 245 ENNILKIN--PIAGTAPRGKTEEE------DKKLAEALLSDEKERAEHVMLVDLARNDVRKVSKSGSVRLERFFDVVKYS 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 405 HVMHLVSRVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVk 484
Cdd:PRK13572 317 HVQHIESEVVGELKEDSTMFDAIEAAFPAGTLTGAPKFRAMEIIDELEKSRRKVYGGAVGYFSNSGNADLAIAIRMAEI- 395
|
250 260
....*....|....*....|....*
gi 780220209 485 EGVAHVQAGAGVVYDSKPQAEADET 509
Cdd:PRK13572 396 DKVCRVRAGAGIVADSVPEKEFYET 420
|
|
| PRK13567 |
PRK13567 |
anthranilate synthase component I; Provisional |
152-510 |
1.35e-76 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184148 [Multi-domain] Cd Length: 468 Bit Score: 249.29 E-value: 1.35e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 152 GSFAYDLIA-SFEDLPEVPEGSNDCPDYCFYVAETLITIDHIKQSTQLVAC-LFGGEEDEQLDARYARltaRLESFKQAc 229
Cdd:PRK13567 103 GTCSFDLVRhEFPKLQSIQLEDHKQHDVRLYMVEQVYVFDHYKDELYIIATnQFSNSTKSDLENRVNK---SIEDLTKI- 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 230 qQPLPAPQGTAPLTGALAVDKGDKQFCAEVEKLKGFIRRGDIFQVVPSR---------------SFSLpcpdpvaaYRRL 294
Cdd:PRK13567 179 -QPFMPTQDFDFKTKEIQSNISEERFIEMIQYFKEKITEGDMFQVVPSRiykyahhasqhlnqlSFQL--------YQNL 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 295 KQTNPSPYMFYVQDEGFTLFGASPESAVKfcANSRQVEMYPIAGTRRRGLNPDgsinldLDGRIELELRQDEKEVAEHLM 374
Cdd:PRK13567 250 KRQNPSPYMYYLNIDQPYIVGSSPESFVS--VKDQIVTTNPIAGTIQRGETTQ------IDNENMKQLLNDPKECSEHRM 321
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 375 LVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGK 454
Cdd:PRK13567 322 LVDLGRNDIHRVSKIGTSKITKLMVIEKYEHVMHIVSEVTGKINQNLSPMTVIANLLPTGTVSGAPKLRAIERIYEQYPH 401
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 780220209 455 RRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQAGAGVVYDSKPQAEADETR 510
Cdd:PRK13567 402 KRGVYSGGVGYINCNHNLDFALAIRTMMIDEQYINVEAGCGVVYDSIPEKELNETK 457
|
|
| PLN02445 |
PLN02445 |
anthranilate synthase component I |
152-509 |
1.09e-74 |
|
anthranilate synthase component I
Pssm-ID: 215244 [Multi-domain] Cd Length: 523 Bit Score: 246.13 E-value: 1.09e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 152 GSFAYDLIASFE--DLP--EVPEGSNDCPDYCFYVAETLITIDHIKQSTQLVACLfGGEEDEQLDARYARLTARLESF-- 225
Cdd:PLN02445 124 GYFSYDTVRYVEkkKLPfsGAPEDDRNLPDIHLGLYDDVIVFDHVEKKAYVIHWV-RLDRYSSVEEAYEDGMKRLEALvs 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 226 KQACQQPLPAPQGTAPL-TGALAVDKGD-----KQFCAEVEKLKGFIRRGDIFQVVPS-----RSFSlpcpDPVAAYRRL 294
Cdd:PLN02445 203 RLQDINPPKLSPGSVKLsTNQFGPSLEKsnmtsEEYKNAVLQAKEHILAGDIFQIVLSqrferRTFA----DPFEVYRAL 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 295 KQTNPSPYMFYVQDEGFTLFGASPE--SAVKfcanSRQVEMYPIAGTRRRGLNPDGsinldlDGRIELELRQDEKEVAEH 372
Cdd:PLN02445 279 RIVNPSPYMIYLQARGCILVASSPEilTRVK----KNKIVNRPLAGTRRRGKTPEE------DKALEKDLLADEKQCAEH 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 373 LMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVE 452
Cdd:PLN02445 349 IMLVDLGRNDVGKVSKAGSVKVEKLMNIERYSHVMHISSTVTGELLDHLTSWDALRAALPVGTVSGAPKVRAMELIDELE 428
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 780220209 453 GKRRGSYGGAVGYLNGAGEMDTCIVIRSAFV------------------KEGVAHVQAGAGVVYDSKPQAEADET 509
Cdd:PLN02445 429 VTRRGPYSGGFGGVSFTGDMDIALALRTMVFptaarydtmysykdtnsrREWVAHLQAGAGIVADSDPEDEYREC 503
|
|
| PRK13574 |
PRK13574 |
anthranilate synthase component I; Provisional |
253-509 |
9.94e-74 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184155 [Multi-domain] Cd Length: 420 Bit Score: 240.49 E-value: 9.94e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 253 KQFCAEVEKLKGFIRRGDIFQVVPSRSFSLPCP-DPVAAYRRLKQTNPSPYMFYVQDEGFTLFGASPESAvkFCANSRQV 331
Cdd:PRK13574 158 NNYEKIVSESLEYIRSGYIFQVVLSRFYRYLFSgDPLRIYYNLRRINPSPYMFYLKFDERYLIGSSPELL--FRVQDNIV 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 332 EMYPIAGTRRRGLNPDGSINLdldgriELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVS 411
Cdd:PRK13574 236 ETYPIAGTRPRGSDQEEDLKL------ELELMNSEKDKAEHLMLVDLARNDLGKVCVPGTVRVPELMYVEKYSHVQHIVS 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 412 RVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQ 491
Cdd:PRK13574 310 KVIGTLKKKYNALDVLKATFPAGTVSGAPKPMAMNIIETLEEYKRGPYAGAVGFISADGNAEFAIAIRTAFLNKDLLRIQ 389
|
250
....*....|....*...
gi 780220209 492 AGAGVVYDSKPQAEADET 509
Cdd:PRK13574 390 AGAGIVYDSNPESEYFET 407
|
|
| PRK09070 |
PRK09070 |
aminodeoxychorismate synthase component I; |
117-510 |
1.83e-73 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236371 [Multi-domain] Cd Length: 447 Bit Score: 240.37 E-value: 1.83e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 117 LDEDS---RLKGSSVLDVLRTL-QRELQCQQGKEAL-FMAGSF---AYDLIASFEDLPEVPEGSNDCPDYCFYVAETLIT 188
Cdd:PRK09070 53 LDPDGvtrQLLEGDFLDALDAAwQAERVPHDGESSLpFRGGWAvllDYELAGQVEPILKLPMRTDGLPLALALRAPAAVL 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 189 IDHIKQSTQLVACLFGGEEDEQLDARYARLtarlesfkqacqqPLPAPQGTAPLTGALAVDKGdKQFCAEVEKLKGFIRR 268
Cdd:PRK09070 133 RDRHSGRCVLVAEPGREHLLDQIEADLAAC-------------AALPPLPVWLAPQAVEEDPP-ERFTDGVERVLDYIRA 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 269 GDIFQVVPSRSFSL---PCPDPVAAYRRLKQTNPSPYMFYVQDEGFTLFGASPESAVKFcaNSRQVEMYPIAGTRRRGLN 345
Cdd:PRK09070 199 GDVFQVNLSRAWQAqfaNAVDPAALYARLRAANPAPFSGLFVAAGRAIVSSSPERLVSV--QGGVVQTRPIAGTRPRFAG 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 346 PDgsinldlDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRADLDALH 425
Cdd:PRK09070 277 DD-------DAALIRELVGHPKERAEHVMLIDLERNDLGRICAPGSVEVDELMTVESYAHVHHIVSNVRGRLRDGVTPGE 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 426 AYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQAGAGVVYDSKPQAE 505
Cdd:PRK09070 350 VIRAVFPGGTITGCPKVRCMQIIAELEQTPRGAYTGSFGYLNRDGDMDLNILIRTAEVQGNQVRFRTGAGIVVDSDPERE 429
|
....*
gi 780220209 506 ADETR 510
Cdd:PRK09070 430 LDETR 434
|
|
| PRK05940 |
PRK05940 |
anthranilate synthase component I; |
152-505 |
8.53e-69 |
|
anthranilate synthase component I;
Pssm-ID: 235651 [Multi-domain] Cd Length: 463 Bit Score: 228.85 E-value: 8.53e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 152 GSFAYDLIASFEDLPevPEGSNDCPdycFYVA-----ETLITIDHIKQSTQLVAclfggEEDEQLDaryaRLTARLESFK 226
Cdd:PRK05940 102 GWLGYDLAWEIERLP--HLNPDPLP---FPVAywyepESFAILDHQEQILWLAA-----SDPSQLD----RLEQQLEQPT 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 227 QacQQPLPAPQGTAPLTGALAVDKgdKQFCAEVEKLKGFIRRGDIFQVVPSRSFSLPCP-DPVAAYRRLKQTNPSPYMFY 305
Cdd:PRK05940 168 P--EPDLPLDLRTPPSSLIFYTTQ--QEYEAAVRQAKKYIQAGDIFQANLSLRFQTTTSaDSWQIYRRLQQINPSPFASY 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 306 VQdegfTLFGA----SPESAVKFcaNSRQVEMYPIAGTRRRGLNPDgsinldLDGRIELELRQDEKEVAEHLMLVDLGRN 381
Cdd:PRK05940 244 WR----TPWGDvvscSPERLVQL--QGNQAQTRPIAGTRPRGKTPA------EDQQLAEELLSNIKERAEHIMLVDLERN 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 382 DIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGG 461
Cdd:PRK05940 312 DLGRVCQWGSVEVDELLTIERYSHVIHLVSNVVGTLQPNRDAIDLIRALFPGGTITGCPKVRCMEIIEELEPVRRNLFYG 391
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 780220209 462 AVGYLNGAGEMDTCIVIRSAFV---KEGVAHV--QAGAGVVYDSKPQAE 505
Cdd:PRK05940 392 SCGYLDQRGNLDLNILIRTLLYtplSRGLSTIwgQVGAGIVADSDPEKE 440
|
|
| PRK07508 |
PRK07508 |
aminodeoxychorismate synthase component I; |
230-508 |
3.86e-48 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236035 [Multi-domain] Cd Length: 378 Bit Score: 171.35 E-value: 3.86e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 230 QQPLPAPQGTAPLTGALAVDKGDKQFcaevEKLKGFIRRGDIFQVvpsrsfSLPCP-------DPVAAYRRLKQTNPSPY 302
Cdd:PRK07508 93 ARPSENAARLRDPVARWDFADYAQRF----ERLHRHIRAGDCYQA------NLTFPldarwggDPLALFWALAARQPVGY 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 303 MFYVQDEGFTLFGASPESAVKfCANSRQVEMYPIAGTRRRGLNPDGsinldlDGRIELELRQDEKEVAEHLMLVDLGRND 382
Cdd:PRK07508 163 GALVDLGGPVILSRSPELFFR-VDGEGWIETHPMKGTAPRGATPAE------DARLRAALLNDEKNQAENRMIVDLLRND 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 383 IARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRADL---DALHAYQACmnmGTLTGAPKLRASELIRMVEGKRRGSY 459
Cdd:PRK07508 236 ISRISEVGSLDVPELFDIETYPTVHQMVSRVRARLLPGLglaDIFAALFPC---GSITGAPKIRAMEILRELEPGPRDLY 312
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 780220209 460 GGAVGYLNGAGEMDTCIVIRS-AFVKEGVAHVQAGAGVVYDSKPQAEADE 508
Cdd:PRK07508 313 CGAIGWIAPDGRMRFNVAIRTlSLFPGGRAVFNVGGGIVFDSTAEAEYEE 362
|
|
| pabB |
PRK15465 |
aminodeoxychorismate synthase component 1; |
120-509 |
6.59e-48 |
|
aminodeoxychorismate synthase component 1;
Pssm-ID: 185362 [Multi-domain] Cd Length: 453 Bit Score: 172.80 E-value: 6.59e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 120 DSRLKGSSVLDVLRTLQRELQ----CQQGKEAL-FMAGS---FAYDLIASFEDLPEVPEGSNDCPDYCFYVAETLITIDH 191
Cdd:PRK15465 68 ESEKRTTTTDDPLQVLQQVLDradiRPTHNEDLpFQGGAlglFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDH 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 192 IKQSTQLVAclfggeeDEQLDARYARLTArlesfkqacQQPlpAPQGTAPLTGALAVDKGDKQFCAEVEKLKGFIRRGDI 271
Cdd:PRK15465 148 QRQTVSLLS-------HNDVNARRAWLES---------QQF--SPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDC 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 272 FQVVPSRSFSLPCP-DPVAAYRRLKQTNPSPYMFYVQDEGFTLFGASPESAVKfCANSrQVEMYPIAGTRRRGLNPDGsi 350
Cdd:PRK15465 210 YQVNLAQRFHATYSgDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFIL-CDNS-EIQTRPIKGTLPRLPDPQE-- 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 351 nldlDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRADLDALHAYQAC 430
Cdd:PRK15465 286 ----DSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITARLPEQLHASDLLRAA 361
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 780220209 431 MNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQAGAGVVYDSKPQAEADET 509
Cdd:PRK15465 362 FPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQET 440
|
|
| PLN02889 |
PLN02889 |
oxo-acid-lyase/anthranilate synthase |
176-508 |
2.38e-45 |
|
oxo-acid-lyase/anthranilate synthase
Pssm-ID: 215481 [Multi-domain] Cd Length: 918 Bit Score: 171.18 E-value: 2.38e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 176 PDYCFYVAETLITIDHIKQSTQLVACLFGGEEDEQ-LDARYARLTARLESFKQACQQPLPAPQGTAPLTGALAVDKGDKQ 254
Cdd:PLN02889 566 PDACFFFADNVVVIDHHYDDVYILSLHEGSTATTQwLDDTEQKLLGLKASATRKLEVQTSPTATFSPSKAGFLADKSREQ 645
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 255 FCAEVEKLKGFIRRGDIFQVVPSRSF--SLPCPDPVAAYRRLKQTNPSPYMFYVQ--DEGFTLFGASPESAVKFCANSrQ 330
Cdd:PLN02889 646 YIKDVQKCLKYIKDGESYELCLTTQMrkRIGEIDSLGLYLHLREKNPAPYAAWLNfsNENLCICSSSPERFLKLDRNG-M 724
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 331 VEMYPIAGTRRRGLNPDGsinldlDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLV 410
Cdd:PLN02889 725 LEAKPIKGTIARGSTPEE------DEQLKLQLQYSEKDQAENLMIVDLLRNDLGRVCEPGSVHVPNLMDVESYTTVHTMV 798
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 411 SRVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHV 490
Cdd:PLN02889 799 STIRGKKRSNMSPVDCVRAAFPGGSMTGAPKLRSMELLDSLESSSRGIYSGSIGFFSYNQTFDLNIVIRTVVIHEGEASI 878
|
330
....*....|....*...
gi 780220209 491 QAGAGVVYDSKPQAEADE 508
Cdd:PLN02889 879 GAGGAIVALSNPEDEYEE 896
|
|
| PRK06404 |
PRK06404 |
anthranilate synthase component I; Reviewed |
239-508 |
4.16e-43 |
|
anthranilate synthase component I; Reviewed
Pssm-ID: 102361 [Multi-domain] Cd Length: 351 Bit Score: 156.95 E-value: 4.16e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 239 TAPLTGALAVDKGDKQFCAEVEKLKGFIRRGDIFQVVPSRSFSlPCPDPVAAYRRLKQTNPSPYMFYVQDEGFTLFGASP 318
Cdd:PRK06404 91 KSFKTVKLKGNYNDISLSLKIKELIELIRAGEVLQVVISREFE-ANIDFKEKLSEFINNDRSRYVFYYRFGKYRVVGSSP 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 319 ESAvkFCANSRQVEMYPIAGTRrrglnpDGSINLDldgrielELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLL 398
Cdd:PRK06404 170 ENV--FTVNGNIINVDPIAGTY------DDKILSN-------ELLNSEKDKLEHRMLLDLARNDLSKFADIGTLNVDKVM 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 399 KVDRYSHVMHLVSRVVGTLrADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGyLNGAGEMDTCIVI 478
Cdd:PRK06404 235 KIEEFSSVKHLVSQVTAKF-SNASYRDILASMFPAGTVSGSPKERAIEIINKYEETPRGPYGGAIG-IISKGYTDMALVI 312
|
250 260 270
....*....|....*....|....*....|
gi 780220209 479 RSAFVKEGVAHVQAGAGVVYDSKPQAEADE 508
Cdd:PRK06404 313 RTAYSHGNGFRVRAGAGIVKDSDPEDEVNE 342
|
|
| MenF |
COG1169 |
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ... |
254-509 |
8.42e-39 |
|
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440783 [Multi-domain] Cd Length: 353 Bit Score: 145.29 E-value: 8.42e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 254 QFCAEVEKLKGFIRRGDIFQVVPSRSFSLPCPDPVAAY---RRLKQTNPSPYMFYVQ-DEGFTLFGASPESAVKfcANSR 329
Cdd:COG1169 90 EWREAVAQALEAIRAGELDKVVLARALDLTLDEPIDPRallARLRRRNPDCYTFAVElGAGDGFVGASPERLVR--RRGG 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 330 QVEMYPIAGTRRRGLNPDgsinldLDGRIELELRQDEKEVAEHLMLVDlgrnDIARISAPGTRYVK--DLLKVDRYSHVM 407
Cdd:COG1169 168 QLTTEALAGTAPRGADPE------EDAALAAALLASEKDRREHALVVD----SIREALAPLCSSLDvpEEPELLRLRNVQ 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 408 HLVSRVVGTLRADLDALHAYQA-------CmnmgtltGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRS 480
Cdd:COG1169 238 HLATPITGTLDPGVSALDLAAAlhptpavG-------GTPREAALALIRELEPFDRGWYAGPVGWVDADGDGEFAVAIRS 310
|
250 260
....*....|....*....|....*....
gi 780220209 481 AFVKEGVAHVQAGAGVVYDSKPQAEADET 509
Cdd:COG1169 311 ALIDGNRARLFAGAGIVAGSDPEAEWAET 339
|
|
| PRK05877 |
PRK05877 |
aminodeoxychorismate synthase component I; Provisional |
266-508 |
5.77e-32 |
|
aminodeoxychorismate synthase component I; Provisional
Pssm-ID: 235634 [Multi-domain] Cd Length: 405 Bit Score: 127.51 E-value: 5.77e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 266 IRRGDIFQVVPSRSFSLPCP-DPV----AAYRRlkqTNPSPYMFYVQDEGfTLFGASPESAVKFCANSrqVEMYPIAGTR 340
Cdd:PRK05877 155 IAAGEVYQACVCTQFTGTVTgSPLdffaDGVAR---TAPARAAYLAGDWG-AVASLSPELFLRRRGSV--VTSSPIKGTL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 341 RRGLNPDgsinldldgrielELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRAD 420
Cdd:PRK05877 229 PLDADPS-------------ALRASAKDVAENIMIVDLVRNDLGRVARTGTVTVPELLVVRPAPGVWHLVSTVSAQVPDE 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 421 LDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSA-FVKEGVAHVQAGAGVVYD 499
Cdd:PRK05877 296 LPMSDLLDATFPPASVTGTPKLRARELISQWEPVRRGIYCGTVGLASPVAGCELNVAIRTVeFDADGNAVLGVGGGITAD 375
|
....*....
gi 780220209 500 SKPQAEADE 508
Cdd:PRK05877 376 SDPDAEWQE 384
|
|
| PRK06772 |
PRK06772 |
salicylate synthase; |
238-510 |
5.38e-29 |
|
salicylate synthase;
Pssm-ID: 102546 [Multi-domain] Cd Length: 434 Bit Score: 119.46 E-value: 5.38e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 238 GTAPLTGALAVDKG--DKQFCAEVEKLKGFIRRGDIFQVVPSRSFSLPCP-DPVAAYRRLKQTNPSPYMFYVQDEGFTLF 314
Cdd:PRK06772 156 GTTTQNAPLAVDTAlnGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRiDMPATLLYGRQANTPVRSFMFRQEGREAL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 315 GASPESAVKFCANSRQVEmyPIAGTRRRGLNPDGsinldlDGRIELELRQDEKEVAEHLMLVDLGRNDIARISAPGTRYV 394
Cdd:PRK06772 236 GFSPELVMSVTGNKVVTE--PLAGTRDRMGNPEH------NKAKEAELLHDSKEVLEHILSVKEAIAELEAVCQPGSVVV 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 395 KDLLKVDRYSHVMHLVSRVVGTLRADLDALHAYQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAgEMDT 474
Cdd:PRK06772 308 EDLMSVRQRGSVQHLGSGVSGQLAENKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDT-RFDA 386
|
250 260 270
....*....|....*....|....*....|....*.
gi 780220209 475 CIVIRSAFVKEGVAHVQAGAGVVYDSKPQAEADETR 510
Cdd:PRK06772 387 ALVLRSVFQDSQRCWIQAGAGIIAQSTPERELTETR 422
|
|
| PRK07912 |
PRK07912 |
salicylate synthase; |
190-509 |
7.59e-29 |
|
salicylate synthase;
Pssm-ID: 169151 [Multi-domain] Cd Length: 449 Bit Score: 119.13 E-value: 7.59e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 190 DHIKQSTQLvACLFGGEEDEQLDARYARLTARLESFKQACQQPLPAPQGTAPLTGALAVDKGDKQFCAEVEKLKGFIRRG 269
Cdd:PRK07912 122 QRLAPGTPL-ARVFSPRTRIVVTEKGIRLFGAGIRHREAIDRLLATGVREVPQSRSVDVSDDPSGYRDRVAVAVAEIAAG 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 270 DIFQVVPSRSFSLP-CPDPVAAYRRLKQTNPSPYMFYVQDEGFTLFGASPE--SAVKfcaNSRQVEMYPIAGTRRRGLNP 346
Cdd:PRK07912 201 RYHKVILSRCVEVPfAVDFPATYRLGRRHNTPVRSFLLRLGGIRALGYSPElvTAVR---ADGVVITEPLAGTRAFGRGA 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 347 DgsinLDLDGRIELElrQDEKEVAEHLMLVDLGRNDIARISAPGTRYVKDLLKVDRYSHVMHLVSRVVGTLRADLDALHA 426
Cdd:PRK07912 278 A----IDRLARDDLE--SNSKEIVEHAISVRSSLAEITEIAEPGSAAVIDFMTVRERGSVQHLGSTVRGRLDASSDRMDA 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 427 YQACMNMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQAGAGVVYDSKPQAEA 506
Cdd:PRK07912 352 LEALFPAVTASGIPKAAGVDAIFRLDEAPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREF 431
|
...
gi 780220209 507 DET 509
Cdd:PRK07912 432 EET 434
|
|
| PRK07054 |
PRK07054 |
isochorismate synthase; |
206-509 |
5.67e-28 |
|
isochorismate synthase;
Pssm-ID: 235920 [Multi-domain] Cd Length: 475 Bit Score: 116.79 E-value: 5.67e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 206 EEDEQLDARYARLTARLESFKQacqqPLPAPQGTAPLTGALAVDKGDkQFCAEVEKLKGFIRRGDIFQVVPSRSFSLPCP 285
Cdd:PRK07054 153 AAHDDPAALAGACCARIERLAR----PAPAADDDAPRLLRASALQAR-EWQHEVRRAVDAIRGGAFGKVVLARDVLQQYA 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 286 DPVAAY---RRLKQTNPSPYMFYVQDEGFTLFGASPESAVKFCANsrQVEMYPIAGTRRRGLNPDGsinldlDGRIELEL 362
Cdd:PRK07054 228 RPVAIGpllRRLRLRDPHAHLFAFRRGNACFLGATPERLVRVAAG--DLHTHALAGTIARGADPAE------DARLGAAL 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 363 RQDEKEVAEHLMLVDLGRNDIARISApgTRYVKDLLKVDRYSHVMHLVSRVVGTLRADLDALHAYQACMNMGTLTGAPKL 442
Cdd:PRK07054 300 MASAKDRLEHALVVDAIRAALAPLSR--ALDIPDQPSLHRLPRLQHLSTPIRATLAPDATLLQVVAALHPTPAVGGHPRA 377
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 780220209 443 RASELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQAGAGVVYDSKPQAEADET 509
Cdd:PRK07054 378 AALDYIRAHEGFDRGWYAAPIGWLDAHGNGDFAVALRSALITGGACRLFAGCGIVADSEPASEYRET 444
|
|
| PRK06923 |
PRK06923 |
isochorismate synthase DhbC; Validated |
231-509 |
9.14e-22 |
|
isochorismate synthase DhbC; Validated
Pssm-ID: 235886 [Multi-domain] Cd Length: 399 Bit Score: 97.50 E-value: 9.14e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 231 QPLPAPQGTApltgalavdKGDKQFCAEveklkgfIRRGDIFQVVPSRSFSLPCPDPV---AAYRRLKQTNPSPYMFYV- 306
Cdd:PRK06923 116 TPVPDPEVYM---------NGVKQGIAK-------IQDGDLKKIVLSRSLDVKSSEKIdkqKLLRELAEHNKHGYTFAVn 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 307 --QDEG---FTLFGASPESAVkfcanSR---QVEMYPIAGTRRRGLNPDGsinldlDGRIELELRQDEKEVAEHLMLVDl 378
Cdd:PRK06923 180 lpKDENensKTLIGASPELLV-----SRhgmQVISNPLAGSRPRSDDPVE------DKRRAEELLSSPKDLHEHAVVVE- 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 379 grnDIARISAPGTRyvkdLLKVDR-----YSHVM-HLVSRVVGTLRaDLD--------ALHAYQAcmnmgtLTGAPKLRA 444
Cdd:PRK06923 248 ---AVAAALRPYCH----TLHVPEkpsviHTEAMwHLSTEVKGELK-DPNtsslelaiALHPTPA------VCGTPTEEA 313
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 780220209 445 SELIRMVEGKRRGSYGGAVGYLNGAGEMDTCIVIRSAFVKEGVAHVQAGAGVVYDSKPQAEADET 509
Cdd:PRK06923 314 REAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVEENTLRLYAGAGVVAESKPEDELAET 378
|
|
| PRK07093 |
PRK07093 |
para-aminobenzoate synthase component I; Validated |
282-508 |
2.96e-19 |
|
para-aminobenzoate synthase component I; Validated
Pssm-ID: 235932 [Multi-domain] Cd Length: 323 Bit Score: 88.77 E-value: 2.96e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 282 LPCPDPVAAYRRLKQ----TNpSPYMFYVQDEgFTLFgaSPESAVKFCANsrQVEMYPIAGTrrrglnpdgsINLDLDGR 357
Cdd:PRK07093 97 LTYPTPIETNLSLEEifqaSK-AKYKLLFKDQ-FVCF--SPEPFVRIEDN--KISTYPMKGT----------IDASLPNA 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 358 IELeLRQDEKEVAEHLMLVDLGRNDIARISapgtryvkDLLKVDRYSHVMHLV----------SRVVGTLRADLDAlhay 427
Cdd:PRK07093 161 EEK-LLNDEKEFAEHATIVDLLRNDLSMVA--------KNVRVTRFRYIDKIKtnkgeilqtsSEISGTLPENWQE---- 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 428 qacmNMGTL----------TGAPKLRASELIRMVEGKRRGSYGGAVGYLNGaGEMDTCIVIRsaFVKE--GVAHVQAGAG 495
Cdd:PRK07093 228 ----NIGDIlakllpagsiTGAPKEKTVEIIEQAEGYERGFYTGVFGYFDG-ESLDSAVMIR--FIEQenDGLYFKSGGG 300
|
250
....*....|...
gi 780220209 496 VVYDSKPQAEADE 508
Cdd:PRK07093 301 ITIDSDLKDEYNE 313
|
|
| PLN02786 |
PLN02786 |
isochorismate synthase |
259-508 |
7.67e-19 |
|
isochorismate synthase
Pssm-ID: 178383 [Multi-domain] Cd Length: 533 Bit Score: 89.84 E-value: 7.67e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 259 VEKLKGFIRRG--DIFQVVPSRSFSL---PCPDPVAAYRRLKQTNPSPYMFYVQDEGFTLF-GASPESAvkFCANSRQVE 332
Cdd:PLN02786 266 VNKALQIIKRKssPLKKVVLARSSRIitdTDIDPIAWLACLQVEGQNAYQFCLQPPDAPAFiGNTPEQL--FHRKGLGVC 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 333 MYPIAGTRRRGlnpdGSINLDLDgrIELELRQDEKEVAEHLMLVDLGRNDIARI-SAPGTRYVKDLLKVDRyshVMHLVS 411
Cdd:PLN02786 344 SEALAATRPRG----GSSARDLQ--IELDLLTSPKDDLEFSIVRENIREKLEAIcDRVVVEPHKAIRKLAR---VQHLYA 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 412 RVVGTLRADLD------ALHAYQAcmnmgtLTGAPKLRASELIRMVEGKRRGSYGGAVGYLnGAGEMDTCIVIRSAFVKE 485
Cdd:PLN02786 415 QLAGRLRSEDDefdilaALHPTPA------VCGHPTEEARLLIAETESFDRGMYAGPVGWF-GGGESEFAVGIRSALVEK 487
|
250 260
....*....|....*....|....
gi 780220209 486 GV-AHVQAGAGVVYDSKPQAEADE 508
Cdd:PLN02786 488 GLgALIYAGTGIVEGSNPSSEWNE 511
|
|
| Anth_synt_I_N |
pfam04715 |
Anthranilate synthase component I, N terminal region; Anthranilate synthase (EC:4.1.3.27) ... |
25-198 |
3.63e-16 |
|
Anthranilate synthase component I, N terminal region; Anthranilate synthase (EC:4.1.3.27) catalyzes the first step in the biosynthesis of tryptophan. Component I catalyzes the formation of anthranilate using ammonia and chorismate. The catalytic site lies in the adjacent region, described in the chorismate binding enzyme family (pfam00425). This region is involved in feedback inhibition by tryptophan. This family also contains a region of Para-aminobenzoate synthase component I (EC 4.1.3.-).
Pssm-ID: 428082 [Multi-domain] Cd Length: 140 Bit Score: 75.42 E-value: 3.63e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 25 DPLALYTRLcQDRPNNLLLESVEidSKAGTQSLLLVDACLRIECRGRAVQVRplgdngaallrlleqrlpavitqtrvad 104
Cdd:pfam04715 4 TPLSVYLKL-AGEPHSFLLESAE--GGEGRYSFIGINPLLTIKSKNGEVSVS---------------------------- 52
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 105 elhldfpasdrELDEDSRLKGSSVLDVLRTLQRELQCQQGKEAL-----FMAGSFAYDLIASFEDLPEVPEGSNDCPDYC 179
Cdd:pfam04715 53 -----------GPDGQELEQEDGPLDALRALLARFRIEDSPPTLppfsgGLVGYLGYDLVRYIEKLPRTAPDDLNLPDAR 121
|
170
....*....|....*....
gi 780220209 180 FYVAETLITIDHIKQSTQL 198
Cdd:pfam04715 122 LILYEDLIVFDHQENKLYL 140
|
|
| PRK15016 |
PRK15016 |
isochorismate synthase EntC; Provisional |
255-509 |
3.08e-13 |
|
isochorismate synthase EntC; Provisional
Pssm-ID: 184977 [Multi-domain] Cd Length: 391 Bit Score: 71.44 E-value: 3.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 255 FCAEVEKLKGFIRRGDIFQVVPSRSFSLPC---PDPVAAYRRLKQTNPSPYMFYVQ-DEGFTLFGASPESAVKfcANSRQ 330
Cdd:PRK15016 129 FEAMVARAAALTATPQVDKVVLSRLIDITTdaaIDSGALLERLIAQNPVSYNFHVPlADGGVLLGASPELLLR--KDGER 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 331 VEMYPIAGTRRRglNPDGSINLDLDGRieleLRQDEKEVAEHLMLvdlgrndiarisapgTRYVKDLLKvDRYSHVM--- 407
Cdd:PRK15016 207 FSSLPLAGSARR--QPDEVLDREAGNR----LLASEKDRHEHELV---------------TQAMKEVLR-ERSSELHvps 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 408 -----------HLVSRVVGTLRADLDALHAyqACMNMGT--LTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAGEMDT 474
Cdd:PRK15016 265 spqlittptlwHLATPFEGKANAQENALTL--ACLLHPTpaLSGFPHQAAKQVIAELEPFDRELFGGIVGWCDSEGNGEW 342
|
250 260 270
....*....|....*....|....*....|....*
gi 780220209 475 CIVIRSAFVKEGVAHVQAGAGVVYDSKPQAEADET 509
Cdd:PRK15016 343 VVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRET 377
|
|
| PRK15012 |
PRK15012 |
menaquinone-specific isochorismate synthase; Provisional |
266-508 |
9.22e-08 |
|
menaquinone-specific isochorismate synthase; Provisional
Pssm-ID: 184974 [Multi-domain] Cd Length: 431 Bit Score: 54.46 E-value: 9.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 266 IRRGDIFQVVPSRSFSLPCPDPV------AAYRRLkqtNPSPYMFYVQ-DEGFTLFGASPESAVKFCANSRQVEmyPIAG 338
Cdd:PRK15012 183 IAEGELDKVVLARATDLHFASPVnaaammAASRRL---NLNCYHFYMAfDAENAFLGSSPERLWRRRDKALRTE--ALAG 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 339 TRRRglNPDgsinlDLDGRIELE-LRQDEKEVAEHLMLVDlgrnDIARISAPGTRYVkDLL--KVDRYSHVMHLVSRVVG 415
Cdd:PRK15012 258 TVAN--HPD-----DKQAQQLGEwLMADDKNQRENMLVVE----DICQRLQADTQTL-DVLppQVLRLRKVQHLRRCIWT 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780220209 416 TLRADLDA--LHAYQAcmnMGTLTGAPKLRASELIRMVEGKRRGSYGGAVGYLNGAgEMDTCIVIRSAFVKEGVAHVQAG 493
Cdd:PRK15012 326 SLNKADDVicLHQLQP---TAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQ-QSEFCVSLRSAKVSGNVVRLYAG 401
|
250
....*....|....*
gi 780220209 494 AGVVYDSKPQAEADE 508
Cdd:PRK15012 402 AGIVRGSDPEQEWQE 416
|
|
| |
