|
Name |
Accession |
Description |
Interval |
E-value |
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
295-619 |
3.57e-74 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 242.92 E-value: 3.57e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 295 YIYAMASLQPVDEAVQMVQDYYIYIIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSK 374
Cdd:COG5002 62 LLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSAL 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 375 NINVLSNKLnshigqLEEDIEKERKLEKTRKEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEY--YFQAMEREVDKM 452
Cdd:COG5002 142 LLGLLLLAA------VERDITELERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAADDPEERreYLEIILEEAERL 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 453 DTLILDMLELAKFESGTYKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNI--GPFEVVANQGRIEQVIVNFLTNAIR 530
Cdd:COG5002 216 SRLVNDLLDLSRLESGELKLEKEPVDLAELLEEVVEELRPLAEEKGIELELDLpeDPLLVLGDPDRLEQVLTNLLDNAIK 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 531 YTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNILELHEVEYGVKNTE 610
Cdd:COG5002 296 YTPEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVDKSRSRETGGTGLGLAIVKHIVEAHGGRIWVESEP 375
|
330
....*....|
gi 806950971 611 D-GVLFYFYL 619
Cdd:COG5002 376 GkGTTFTITL 385
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
389-619 |
9.50e-65 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 212.84 E-value: 9.50e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 389 QLEEDIEKERKLEKTRKEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEY--YFQAMEREVDKMDTLILDMLELAKFE 466
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDLSPEERreLLEIIRESAERLLRLIEDLLDLSRLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 467 SGTYKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNI--GPFEVVANQGRIEQVIVNFLTNAIRYTPSKEDIIISTID 544
Cdd:COG2205 81 SGKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLppELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 806950971 545 ERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDaaRQRSQGGTGLGLAISKNILELHEVEYGVKNTED-GVLFYFYL 619
Cdd:COG2205 161 EGDGVRISVSDNGPGIPEEELERIFERFYRGD--NSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGgGTTFTVTL 234
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
389-619 |
1.32e-57 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 197.05 E-value: 1.32e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 389 QLEEDIEKERKLEKTRKEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYyFQAMEREVDKMDTLILDMLELAKFESG 468
Cdd:COG0642 95 LLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEELDEEQREY-LETILRSADRLLRLINDLLDLSRLEAG 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 469 TYKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNI--GPFEVVANQGRIEQVIVNFLTNAIRYTPSKEDIIISTIDER 546
Cdd:COG0642 174 KLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLpdDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVRREG 253
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 806950971 547 NRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRsqGGTGLGLAISKNILELHEVEYGVKNTED-GVLFYFYL 619
Cdd:COG0642 254 DRVRISVEDTGPGIPPEDLERIFEPFFRTDPSRRG--GGTGLGLAIVKRIVELHGGTIEVESEPGkGTTFTVTL 325
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
318-600 |
1.11e-36 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 142.85 E-value: 1.11e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 318 YIIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKNINVLSNKLnshigqleediEKE 397
Cdd:PRK10549 168 LIVALSTLLAALATFLLARGLLAPVKRLVEGTHKLAAGDFTTRVTPTSRDELGRLAQDFNQLASTL-----------EKN 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 398 rklEKTRKEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYyFQAMEREVDKMDTLILDMLELAKFESGTYKMKMDSF 477
Cdd:PRK10549 237 ---EQMRRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPES-VASLQAEVGTLTKLVDDLHQLSLSDEGALAYRKTPV 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 478 yidtvmeDICEHLSVEI-------EKKELRVHKNIGPFEVV-ANQGRIEQVIVNFLTNAIRYTPSKEDIIISTIDERNRL 549
Cdd:PRK10549 313 -------DLVPLLEVAGgafrerfASRGLTLQLSLPDSATVfGDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQRDKTL 385
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 806950971 550 KVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNILELH 600
Cdd:PRK10549 386 RLTFADSAPGVSDEQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAH 436
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
387-623 |
3.63e-33 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 133.37 E-value: 3.63e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 387 IGQLEEDIEK-ERKLEKTRKE---FISGVSHELKTPLSIMKSCISILKDGVAEHKKE---YYFQAMEREVDKMDTLILDM 459
Cdd:COG4251 261 LEELEEELEErTAELERSNEEleqFAYVASHDLREPLRKISGFSQLLEEDYGDKLDEegrEYLERIRDAAERMQALIDDL 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 460 LELAKfeSGTYKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHknIGPF-EVVANQGRIEQVIVNFLTNAIRYTPSKED- 537
Cdd:COG4251 341 LAYSR--VGRQELEFEPVDLNELLEEVLEDLEPRIEERGAEIE--VGPLpTVRGDPTLLRQVFQNLISNAIKYSRPGEPp 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 538 -IIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSqgGTGLGLAISKNILELHEVEYGVKNTED-GVLF 615
Cdd:COG4251 417 rIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSRDEYE--GTGIGLAIVKKIVERHGGRIWVESEPGeGATF 494
|
....*...
gi 806950971 616 YFYLLKKA 623
Cdd:COG4251 495 YFTLPKAP 502
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
312-612 |
1.79e-31 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 127.00 E-value: 1.79e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 312 VQDYYIYIIAFVVVLIFLAS----FYYSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKNINVLSNKLNSHI 387
Cdd:COG5000 3 LQILFLLLLLLIALLLLLLAlwlaLLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKEQR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 388 GQLEE--------------------------------------------------------------------------- 392
Cdd:COG5000 83 EELEErrryletilenlpagvivldadgritlanpaaerllgipleeligkpleellpeldlaellrealergwqeeiel 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 393 -------------------------DIEKERKLEKTR--KEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEY----- 440
Cdd:COG5000 163 trdgrrtllvrasplrddgyvivfdDITELLRAERLAawGELARRIAHEIKNPLTPIQLSAERLRRKLADKLEEDredle 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 441 -YFQAMEREVDKMDTLILDMLELAKFEsgtyKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNIGP--FEVVANQGRI 517
Cdd:COG5000 243 rALDTIIRQVDRLKRIVDEFLDFARLP----EPQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPdlPEVLADRDQL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 518 EQVIVNFLTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFY--RvdaarqrsQGGTGLGLAISKN 595
Cdd:COG5000 319 EQVLINLLKNAIEAIEEGGEIEVSTRREDGRVRIEVSDNGPGIPEEVLERIFEPFFttK--------PKGTGLGLAIVKK 390
|
410
....*....|....*..
gi 806950971 596 ILELHEVEYGVKNTEDG 612
Cdd:COG5000 391 IVEEHGGTIELESRPGG 407
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
285-600 |
1.56e-30 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 124.81 E-value: 1.56e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 285 PIKEKDGSVTYIYAMASLQPVDEavQMVQDYYIYIIAFVVVLIFLASF---YYSKQIAKPLLKINDTTKKIAHLDFTEKI 361
Cdd:TIGR01386 134 ALPGGKGRKPVQITVALDINAHT--HLLDALRKWLILIAVLLVLLTALlgwWITRLGLEPLRRLSAVAARISPESLDQRL 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 362 PITskdeigDLSKNINVLSNKLNSHIGQLEEDIekeRKLEktrkEFISGVSHELKTPLS--IMKSCISILKDGVAEHKKE 439
Cdd:TIGR01386 212 DPS------RAPAELRELAQSFNAMLGRLEDAF---QRLS----QFSADLAHELRTPLTnlLGQTQVALSQPRTGEEYRE 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 440 YYFQAMErEVDKMDTLILDMLELAKFESGTYKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNiGPFEVVANQGRIEQ 519
Cdd:TIGR01386 279 VLESNLE-ELERLSRMVSDMLFLARADNGQLALERVRLDLAAELAKVAEYFEPLAEERGVRIRVE-GEGLVRGDPQMFRR 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 520 VIVNFLTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNILEL 599
Cdd:TIGR01386 357 AISNLLSNALRHTPDGGTITVRIERRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPARSNSGEGTGLGLAIVRSIMEA 436
|
.
gi 806950971 600 H 600
Cdd:TIGR01386 437 H 437
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
376-619 |
1.39e-29 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 120.29 E-value: 1.39e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 376 INVLSNKLNSHIGQLEEDIEKERKLEK----TRK-----EFISGVSHELKTPLSIMKSCISILKDGVAEHKK----EYYF 442
Cdd:COG4191 105 ENAELEELERDITELERAEEELRELQEqlvqSEKlaalgELAAGIAHEINNPLAAILGNAELLRRRLEDEPDpeelREAL 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 443 QAMEREVDKMDTLILDMLELAKFESGtykmKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNIGP--FEVVANQGRIEQV 520
Cdd:COG4191 185 ERILEGAERAAEIVRSLRAFSRRDEE----EREPVDLNELIDEALELLRPRLKARGIEVELDLPPdlPPVLGDPGQLEQV 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 521 IVNFLTNAIRYTPSKED--IIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFY---RVdaarqrsQGGTGLGLAISKN 595
Cdd:COG4191 261 LLNLLINAIDAMEEGEGgrITISTRREGDYVVISVRDNGPGIPPEVLERIFEPFFttkPV-------GKGTGLGLSISYG 333
|
250 260
....*....|....*....|....*..
gi 806950971 596 ILELH--EVEygVKNTED-GVLFYFYL 619
Cdd:COG4191 334 IVEKHggRIE--VESEPGgGTTFTITL 358
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
319-623 |
6.20e-27 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 114.48 E-value: 6.20e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 319 IIAFVVVLIFLASFYyskQIAKPLLKINDTTKKIAHLDFTEKI-PITSKDEIGDLskninVLSnkLNSHIGQLEEDIeke 397
Cdd:PRK09835 193 VISLLIVFIVLLAVH---KGHAPIRSVSRQIQNITSKDLDVRLdPQTVPIELEQL-----VLS--FNHMIERIEDVF--- 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 398 rklekTRK-EFISGVSHELKTPLS--IMKSCISILKDGVAEHKKEYYFQAMErEVDKMDTLILDMLELAKFESgtykmkm 474
Cdd:PRK09835 260 -----TRQsNFSADIAHEIRTPITnlITQTEIALSQSRSQKELEDVLYSNLE-ELTRMAKMVSDMLFLAQADN------- 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 475 DSFYIDTVMEDicehLSVEI-----------EKKELRVHKNIGPFEVVANQGRIEQVIVNFLTNAIRYTPSKEDIIISTI 543
Cdd:PRK09835 327 NQLIPEKKMLD----LADEVgkvfdffeawaEERGVELRFVGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQ 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 544 DERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNILELHEVEYGVKNTEDGVLFYFYLLKKA 623
Cdd:PRK09835 403 EVDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSDARGTRFVISLPRLE 482
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
512-619 |
1.05e-26 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 104.65 E-value: 1.05e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 512 ANQGRIEQVIVNFLTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDaARQRSQGGTGLGLA 591
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTD-KRSRKIGGTGLGLS 79
|
90 100
....*....|....*....|....*....
gi 806950971 592 ISKNILELHEVEYGVKNTED-GVLFYFYL 619
Cdd:smart00387 80 IVKKLVELHGGEISVESEPGgGTTFTITL 108
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
393-619 |
1.49e-26 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 112.80 E-value: 1.49e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 393 DIEKERKLEKTRKEFISGVSHELKTPLSIMKSCISILKDGVAEHK-KEYYFQAMEREVDKMDTLILDMLELAKFESGTYK 471
Cdd:PRK11006 193 DVTQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMQDQPLEGAlREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTI 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 472 MKMDSfyIDT-VMEDICEHLSVEIEKKELRVHKNIGP-FEVVANQGRIEQVIVNFLTNAIRYTPSKEDIIISTIDERNRL 549
Cdd:PRK11006 273 DLNEK--VDVpMMLRVLEREAQTLSQGKHTITFEVDNsLKVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQGA 350
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 806950971 550 KVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNILELHEVEYGVKNTED-GVLFYFYL 619
Cdd:PRK11006 351 EFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGkGTRFSFVL 421
|
|
| his_kin_PieS |
NF041210 |
two component system sensor histidine kinase PieS; |
285-619 |
2.62e-24 |
|
two component system sensor histidine kinase PieS;
Pssm-ID: 469114 [Multi-domain] Cd Length: 474 Bit Score: 106.41 E-value: 2.62e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 285 PIKEKDGSVTYIYAMASLQPVDEAVQMVQDYYIYIIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEKIPIT 364
Cdd:NF041210 138 PILNGDEFLGSIILNSPISGTEKVIGTINQYMFYTILLSITIALILSAILSKLQVNRINKLRKATKRVIRGNYETRLKEN 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 365 SKDEIGDLSKNINvlsnKLNSHIGQLEEDIEKErklEKTRKEFISGVSHELKTPLSImkscISILKDG-----VAEHKKE 439
Cdd:NF041210 218 NFDEIGALAHDFN----KMTETLAESKEEIERQ---EKRRRQFIADVSHEMRTPLTT----ISGLTEGlvndiIPKSETD 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 440 YYFQAMEREVDKMDTLILDMLELAKFESGTYKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNI-GPFEVVANQGRIE 518
Cdd:NF041210 287 RCIALIDTEAKRLTKLVNENLDYERIRSNKIQLYKTRFGVHAFLDLIKEQLEPLASEKGNQIIVDApLDLEVYADYDRLT 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 519 QVIVNFLTNAIRYTpSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQ-GGTGLGLAISKNIL 597
Cdd:NF041210 367 QIVINIVKNSIQFT-ENGTITLTGRQDYKETILTITDTGIGMDTGELEQIWERFYKADMSRTSTAfGESGIGLSIVKQLV 445
|
330 340
....*....|....*....|...
gi 806950971 598 ELHEVEYGVKNT-EDGVLFYFYL 619
Cdd:NF041210 446 EYHDGSIEVESEpNKGTTFTIRL 468
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
383-600 |
2.97e-24 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 106.17 E-value: 2.97e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 383 LNSHIGQLEEDIEKERKLektrkefISGVSHELKTPLSIMKSCISILKDGVAEHKKeyyFQAMEREVDKMDTLILDMLEL 462
Cdd:PRK09470 229 FNQMVTALERMMTSQQRL-------LSDISHELRTPLTRLQLATALLRRRQGESKE---LERIETEAQRLDSMINDLLVL 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 463 AkfesgtyKMKMDS------FYIDTVMEDICEHLSVEIE--KKELRVHKNIGPFEVVANQGRIEQVIVNFLTNAIRYTPS 534
Cdd:PRK09470 299 S-------RNQQKNhleretFKANSLWSEVLEDAKFEAEqmGKSLTVSAPPGPWPINGNPNALASALENIVRNALRYSHT 371
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 806950971 535 KedIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNILELH 600
Cdd:PRK09470 372 K--IEVAFSVDKDGLTITVDDDGPGVPEEEREQIFRPFYRVDEARDRESGGTGLGLAIVENAIQQH 435
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
392-603 |
6.31e-24 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 103.77 E-value: 6.31e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 392 EDIEKERKLEKTR---------KEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDTLILDMLEL 462
Cdd:COG3852 114 RDITERKRLERELrraeklaavGELAAGLAHEIRNPLTGIRGAAQLLERELPDDELREYTQLIIEEADRLNNLVDRLLSF 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 463 AKFESgtykMKMDSFYIDTVMEDICEHLSVEIeKKELRVHKNIGP--FEVVANQGRIEQVIVNFLTNAIRYTPSKEDIII 540
Cdd:COG3852 194 SRPRP----PEREPVNLHEVLERVLELLRAEA-PKNIRIVRDYDPslPEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITI 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 541 ST--------IDERNRLKVCIE---NkGTHIEEEQLDKIWDRFY--RvdaarqrsQGGTGLGLAISKNILELH----EVE 603
Cdd:COG3852 269 RTrverqvtlGGLRPRLYVRIEvidN-GPGIPEEILDRIFEPFFttK--------EKGTGLGLAIVQKIVEQHggtiEVE 339
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
392-619 |
1.53e-23 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 104.29 E-value: 1.53e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 392 EDIEKERKLEKTRK-----EFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYyFQAMEREVDKMDTLILDMLELAKFE 466
Cdd:COG5809 253 ERKKLEELLRKSEKlsvvgELAAGIAHEIRNPLTSLKGFIQLLKDTIDEEQKTY-LDIMLSELDRIESIISEFLVLAKPQ 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 467 SgtykMKMDSFYIDTVMEDICEHLSVE--IEKKELRVHKNIGPFEVVANQGRIEQVIVNFLTNAIRYTPSKEDIIIST-I 543
Cdd:COG5809 332 A----IKYEPKDLNTLIEEVIPLLQPQalLKNVQIELELEDDIPDILGDENQLKQVFINLLKNAIEAMPEGGNITIETkA 407
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 806950971 544 DERNRLKVCIENKGTHIEEEQLDKIWDRFYrvdaarQRSQGGTGLGLAISKNILELHEVEYGVKNTED-GVLFYFYL 619
Cdd:COG5809 408 EDDDKVVISVTDEGCGIPEERLKKLGEPFY------TTKEKGTGLGLMVSYKIIEEHGGKITVESEVGkGTTFSITL 478
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
413-612 |
6.68e-23 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 102.23 E-value: 6.68e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 413 HELKTPLSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDTLILDMLELAKFESGTYKMKMDSFYIDTVMEDICEHLSV 492
Cdd:PRK11100 265 HELKSPLAAIRGAAELLQEDPPPEDRARFTGNILTQSARLQQLIDRLLELARLEQRQELEVLEPVALAALLEELVEAREA 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 493 EIEKKELRVHKNIGPFEVVANQGRIEQVIVNFLTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRF 572
Cdd:PRK11100 345 QAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGIPDYALPRIFERF 424
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 806950971 573 Y---RVDAARQrsqgGTGLGLAISKNILELHEVEYGVKNTEDG 612
Cdd:PRK11100 425 YslpRPANGRK----STGLGLAFVREVARLHGGEVTLRNRPEG 463
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
512-619 |
4.17e-21 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 88.58 E-value: 4.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 512 ANQGRIEQVIVNFLTNAIRYTPSKEDIIIsTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDaarQRSQGGTGLGLA 591
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITV-TLSEGGELTLTVEDNGIGIPPEDLPRIFEPFSTAD---KRGGGGTGLGLS 76
|
90 100
....*....|....*....|....*....
gi 806950971 592 ISKNILELHEVEYGVKNTED-GVLFYFYL 619
Cdd:pfam02518 77 IVRKLVELLGGTITVESEPGgGTTVTLTL 105
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
316-614 |
5.48e-21 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 96.13 E-value: 5.48e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 316 YIYIIAFVVVLiflASFYYSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKNINVLSnklnSHIGQLEEDie 395
Cdd:PRK09467 158 YTLAIGLLSVA---GGWLFIRIQNRPLVALEHAALQVGKGEIPPPLREYGASEVRSVTRAFNQMA----AGIKQLEDD-- 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 396 keRKLektrkeFISGVSHELKTPLS-------IMKSCISILKDGvaehkkeyyfqaMEREVDKMDTLI---LDMLELAKf 465
Cdd:PRK09467 229 --RTL------LMAGVSHDLRTPLTrirlateMMSEEDGYLAES------------INKDIEECNAIIeqfIDYLRTGQ- 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 466 esgtyKMKMDSFYIDTVMEDIcehLSVEIE-KKELRVHKNIGPFEVVANQGRIEQVIVNFLTNAIRYtpSKEDIIISTID 544
Cdd:PRK09467 288 -----EMPMEMADLNALLGEV---IAAESGyEREIETALQPGPIEVPMNPIAIKRALANLVVNAARY--GNGWIKVSSGT 357
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 545 ERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSqgGTGLGLAISKNILELHEVEYGVKNTEDGVL 614
Cdd:PRK09467 358 EGKRAWFQVEDDGPGIPPEQLKHLFQPFTRGDSARGSS--GTGLGLAIVKRIVDQHNGKVELGNSEEGGL 425
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
517-619 |
2.32e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 86.39 E-value: 2.32e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIVNFLTNAIRYTPSKE-DIIISTIDE---RNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAI 592
Cdd:cd16922 1 LRQILLNLLGNAIKFTEEGEvTLRVSLEEEeedGVQLRFSVEDTGIGIPEEQQARLFEPFSQADSSTTRKYGGTGLGLAI 80
|
90 100
....*....|....*....|....*...
gi 806950971 593 SKNILELHEVEYGVKNTED-GVLFYFYL 619
Cdd:cd16922 81 SKKLVELMGGDISVESEPGqGSTFTFTL 108
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
516-600 |
2.73e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 86.36 E-value: 2.73e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 516 RIEQVIVNFLTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKN 595
Cdd:cd16946 4 RLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSGLGLAICHN 83
|
....*
gi 806950971 596 ILELH 600
Cdd:cd16946 84 IALAH 88
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
253-596 |
4.02e-19 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 92.01 E-value: 4.02e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 253 TDVVLKESNQIEYSTKTMDYEKNDIKYKLLMKPIKEKDGSVT---YIYAMASLQPV--------------DEAVQMVQDY 315
Cdd:PRK15347 219 INLWLDQNGELLPFSTIPLSSNQLQKILNQLENVKLHDGWQQipdYLVLRTQLKGPgwqqvtlyprrnlaNEALKPALQQ 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 316 YIYIIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKNINVLSNKLNSHIGQLEEDI- 394
Cdd:PRK15347 299 LPFALLILVLLTSVLFLLLRRYLAKPLWRFVDIINKTGPAALEPRLPENRLDELGSIAKAYNQLLDTLNEQYDTLENKVa 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 395 EKERKLEKTRK----------EFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDTLILDMLELAK 464
Cdd:PRK15347 379 ERTQALAEAKQraeqankrksEHLTTISHEIRTPLNGVLGALELLQNTPLTAEQMDLADTARQCTLSLLAIINNLLDFSR 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 465 FESGTYKMKMDSF----YIDTVMEDIceHLSVEIEKKELR--VHKNIgPFEVVANQGRIEQVIVNFLTNAIRYTPSKEdI 538
Cdd:PRK15347 459 IESGQMTLSLEETallpLLDQAMLTI--QGPAQSKSLTLRtfVGAHV-PLYLHLDSLRLRQILVNLLGNAVKFTETGG-I 534
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 806950971 539 IISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQrsqgGTGLGLAISKNI 596
Cdd:PRK15347 535 RLRVKRHEQQLCFTVEDTGCGIDIQQQQQIFTPFYQADTHSQ----GTGLGLTIASSL 588
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
517-600 |
1.19e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 81.60 E-value: 1.19e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIVNFLTNAIRYTPSKedIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNI 596
Cdd:cd16949 1 LARALENVLRNALRYSPSK--ILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGLGLAIAERA 78
|
....
gi 806950971 597 LELH 600
Cdd:cd16949 79 IEQH 82
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
389-619 |
1.61e-18 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 87.70 E-value: 1.61e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 389 QLEEDI-----EKERKLEKTR-KE-FISGVSHELKTPLSIMKSCISILK----DGVAEHK---KEYYFQAMEREVDKMDT 454
Cdd:PRK09303 129 QLSDELfvlrqENETLLEQLKfKDrVLAMLAHDLRTPLTAASLALETLElgqiDEDTELKpalIEQLQDQARRQLEEIER 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 455 LILDMLELAKFESGTYKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNIG---PfEVVANQGRIEQVIVNFLTNAIRY 531
Cdd:PRK09303 209 LITDLLEVGRTRWEALRFNPQKLDLGSLCQEVILELEKRWLAKSLEIQTDIPsdlP-SVYADQERIRQVLLNLLDNAIKY 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 532 TPSKEDIIISTIDERN-RLKVCIENKGTHIEEEQLDKIWDRFYRVDaaRQRSQGGTGLGLAISKNILELHeveYG----V 606
Cdd:PRK09303 288 TPEGGTITLSMLHRTTqKVQVSICDTGPGIPEEEQERIFEDRVRLP--RDEGTEGYGIGLSVCRRIVRVH---YGqiwvD 362
|
250
....*....|...
gi 806950971 607 KNTEDGVLFYFYL 619
Cdd:PRK09303 363 SEPGQGSCFHFTL 375
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
332-619 |
2.02e-18 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 89.26 E-value: 2.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 332 FYYSKQIAKPLLkinDTTKK-IAHLDFTEKIPiTSKDEIgDLSKNINVLSNKLNSHIGQLE--EDIEKERKLEK------ 402
Cdd:PRK11360 311 FPPNTPFASPLL---DTLEHgTEHVDLEISFP-GRDRTI-ELSVSTSLLHNTHGEMIGALVifSDLTERKRLQRrvarqe 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 403 ---TRKEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDTLILDMLELAKfesgTYKMKMDSFYI 479
Cdd:PRK11360 386 rlaALGELVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQEYLSVVLREVDRLNKVIDQLLEFSR----PRESQWQPVSL 461
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 480 DTVMEDICEHLSVEIEKKELRVHKNIGPF--EVVANQGRIEQVIVNFLTNAIRYTPSKEDIIISTIDERN-RLKVCIENK 556
Cdd:PRK11360 462 NALVEEVLQLFQTAGVQARVDFETELDNElpPIWADPELLKQVLLNILINAVQAISARGKIRIRTWQYSDgQVAVSIEDN 541
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 806950971 557 GTHIEEEQLDKIWDRFYRVDAArqrsqgGTGLGLAISKNILELHEVEYGVKNTED-GVLFYFYL 619
Cdd:PRK11360 542 GCGIDPELLKKIFDPFFTTKAK------GTGLGLALSQRIINAHGGDIEVESEPGvGTTFTLYL 599
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
392-600 |
1.43e-17 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 85.94 E-value: 1.43e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 392 EDIEKERKLEKT--RKEFIS-------GVSHELKTPLSIMKSCISILKDGVAEHKKeyYFQAMEREVDKMDTLILDMLEL 462
Cdd:COG5805 266 RDITEKKEAEELmaRSEKLSiagqlaaGIAHEIRNPLTSIKGFLQLLQPGIEDKEE--YFDIMLSELDRIESIISEFLAL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 463 AKfESGTYKMKMDsfyIDTVMEDICEHLSVE--IEKKELRVHKNIGPFEVVANQGRIEQVIVNFLTNAIRYTPSKEDIII 540
Cdd:COG5805 344 AK-PQAVNKEKEN---INELIQDVVTLLETEaiLHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITI 419
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 541 STIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVdaarqrSQGGTGLGLAISKNILELH 600
Cdd:COG5805 420 HTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFFTT------KEKGTGLGLMVSYKIIENH 473
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
520-611 |
6.67e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 76.27 E-value: 6.67e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 520 VIVNFLTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQrsQGGTGLGLAISKNILEL 599
Cdd:cd16923 4 VFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRN--TEGAGLGLSIAKAIIEL 81
|
90
....*....|....
gi 806950971 600 H--EVEYGVKNTED 611
Cdd:cd16923 82 HggSASAEYDDNHD 95
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
319-601 |
1.02e-16 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 83.97 E-value: 1.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 319 IIAFVVVL---IFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKNINVLSNKLNSHIGQLEEDIE 395
Cdd:COG4192 329 LAIALLSLllaVLINYFYVRRRLVKRLNALSDAMAAIAAGDLDVPIPVDGNDEIGRIARLLRVFRDQAIEKTQELETEIE 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 396 KERK----LEKTRKEFI------------SGVSHELKTPLSIMKSCISILKDGVAEHKKE---YYFQAMEREVDKMDTLI 456
Cdd:COG4192 409 ERKRieknLRQTQDELIqaakmavvgqtmTSLAHELNQPLNAMSMYLFSAKKALEQENYAqlpTSLDKIEGLIERMDKII 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 457 LDMLELAKFESGTYKmkmdSFYIDTVMEDICEhlSVEIEKKELRVHKNI-GPFEVVANQGRIEQVIVNFLTNAIRYTPSK 535
Cdd:COG4192 489 KSLRQFSRKSDTPLQ----PVDLRQVIEQAWE--LVESRAKPQQITLHIpDDLMVQGDQVLLEQVLVNLLVNALDAVATQ 562
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 806950971 536 EDIIISTIDERNRLKVCIENKGTHIEEeqLDKIWDRFYrvdaarQRSQGGTGLGLAISKNILELHE 601
Cdd:COG4192 563 PQISVDLLSNAENLRVAISDNGNGWPL--VDKLFTPFT------TTKEVGLGLGLSICRSIMQQFG 620
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
291-601 |
1.55e-16 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 82.34 E-value: 1.55e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 291 GSVTYIYAMASLQPVDEAVqmvqdyyiyiIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIG 370
Cdd:PRK10604 123 GPVPYLYYLHQMRLLDIAL----------LALIGLSLAFPVFLWMRPHWQDMLKLEAAAQRLGDGHLAERIHFDEGSSLE 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 371 DLSKNINvlsnklnshigQLEEDIEKerkLEKTRKEFISGVSHELKTPLSIMKSCISILKDGVAEHKkeyyfQAMEREVD 450
Cdd:PRK10604 193 RLGVAFN-----------QMADNINA---LIASKKQLIDGIAHELRTPLVRLRYRLEMSDNLSAAES-----QALNRDIG 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 451 KMDTLILDMLELAKFESGTYKMKMDSFYIDTVMEDICEHL-SVEIEKK---ELRVHKNIGpfevVANQGRIEQVIVNFLT 526
Cdd:PRK10604 254 QLEALIEELLTYARLDRPQNELHLSEPDLPAWLSTHLADIqAVTPEKTvrlDTPHQGDYG----ALDMRLMERVLDNLLN 329
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 806950971 527 NAIRYTPSKEDIIISTIDERNRLKVciENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNILELHE 601
Cdd:PRK10604 330 NALRYAHSRVRVSLLLDGNQACLIV--EDDGPGIPPEERERVFEPFVRLDPSRDRATGGCGLGLAIVHSIALAMG 402
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
521-609 |
1.33e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 73.01 E-value: 1.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 521 IVNFLTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNILELH 600
Cdd:cd16952 5 FSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGLGLAIVKHVMSRH 84
|
....*....
gi 806950971 601 EVEYGVKNT 609
Cdd:cd16952 85 DARLLIASE 93
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
386-619 |
1.84e-15 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 80.08 E-value: 1.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 386 HIGQLEED--IEKERklEKTRKEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDT--LILDMLE 461
Cdd:PRK10490 646 TLTASEEQarLASER--EQLRNALLAALSHDLRTPLTVLFGQAEILTLDLASEGSPHARQASEIRQQVLNTtrLVNNLLD 723
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 462 LAKFESGTYKMKMDSFYIDTVMEDICEHLSVEIEKKELRVhkNIgPFEVV---ANQGRIEQVIVNFLTNAIRYTPSKEDI 538
Cdd:PRK10490 724 MARIQSGGFNLRKEWLTLEEVVGSALQMLEPGLSGHPINL--SL-PEPLTlihVDGPLFERVLINLLENAVKYAGAQAEI 800
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 539 IISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDaaRQRSQGGTGLGLAISKNILELHEVEYGVKNT-EDGVLFYF 617
Cdd:PRK10490 801 GIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFARGN--KESAIPGVGLGLAICRAIVEVHGGTIWAENRpEGGACFRV 878
|
..
gi 806950971 618 YL 619
Cdd:PRK10490 879 TL 880
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
305-606 |
5.53e-15 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 78.23 E-value: 5.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 305 VDEAVQMVQDYYIYIIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKNINVLSNKLN 384
Cdd:COG2770 203 LLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMADSLR 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 385 SHIGQLEEdiEKERKLEKTRKEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDTLILDMLELAK 464
Cdd:COG2770 283 ESIEEAEE--EEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 465 FESGTYKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNIGPFEVVANQGRIEQVIVNFLTNAIRYTPSKEDIIISTID 544
Cdd:COG2770 361 LLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALEL 440
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 806950971 545 ERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNILELHEVEYGV 606
Cdd:COG2770 441 AAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAA 502
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
357-598 |
7.97e-15 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 78.02 E-value: 7.97e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 357 FTEKIPITSKDEIGDLSKNINVLSNKLNSHIGQLEEDIE------------------KERKLEKTRKEFISGVSHELKTP 418
Cdd:PRK11466 379 FPETAGVRELDTIGRLMDAFRSNVHALNRHREQLAAQVKartaelqelviehrqaraEAEKASQAKSAFLAAMSHEIRTP 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 419 LSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDTLILDMLELAKFESGTYKMKM--DSFYIDTVMEDICEHLSVEIEK 496
Cdd:PRK11466 459 LYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAGGKNVSVsdEPFEPRPLLESTLQLMSGRVKG 538
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 497 KELRVHKNIG---PFEVVANQGRIEQVIVNFLTNAIRYTpSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFY 573
Cdd:PRK11466 539 RPIRLATDIAddlPTALMGDPRRIRQVITNLLSNALRFT-DEGSIVLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFV 617
|
250 260
....*....|....*....|....*
gi 806950971 574 RVDAARqrsqGGTGLGLAISKNILE 598
Cdd:PRK11466 618 QVSGKR----GGTGLGLTISSRLAQ 638
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
389-600 |
1.07e-14 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 76.75 E-value: 1.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 389 QLEEDIEKERKLEKTrKEFISGVSHELKTPLSIMKscisilkdGVAEhkkeyYF--------------QAMEREVDKMDT 454
Cdd:PRK10364 223 LLQDEMKRKEKLVAL-GHLAAGVAHEIRNPLSSIK--------GLAK-----YFaerapaggeahqlaQVMAKEADRLNR 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 455 LILDMLELAKFESGTYKmkmdsfyiDTVMEDICEH----LSVEIEKKELRVHKNIGPF--EVVANQGRIEQVIVNFLTNA 528
Cdd:PRK10364 289 VVSELLELVKPTHLALQ--------AVDLNDLINHslqlVSQDANSREIQLRFTANDTlpEIQADPDRLTQVLLNLYLNA 360
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 806950971 529 IRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAArqrsqgGTGLGLAISKNILELH 600
Cdd:PRK10364 361 IQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAE------GTGLGLAVVHNIVEQH 426
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
519-612 |
1.84e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 69.74 E-value: 1.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 519 QVIVNFLTNAIRYTPSKEDIIIsTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAarqRSQGGTGLGLAISKNILE 598
Cdd:cd16940 16 LLLRNLVDNAVRYSPQGSRVEI-KLSADDGAVIRVEDNGPGIDEEELEALFERFYRSDG---QNYGGSGLGLSIVKRIVE 91
|
90
....*....|....
gi 806950971 599 LHEVEYGVKNTEDG 612
Cdd:cd16940 92 LHGGQIFLGNAQGG 105
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
308-592 |
1.95e-14 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 76.08 E-value: 1.95e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 308 AVQMVQDYYIYIIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKNINVLSNKLNSHI 387
Cdd:COG3850 112 AAAINRKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADELQELY 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 388 GQLEEDIEKERKLEKTRKEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDTLILDMLELAkfes 467
Cdd:COG3850 192 AELEEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLL---- 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 468 gtyKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNIGPFEVVANQGRIEQVIVNFLTNAIRYTPSKEDIIISTIDERN 547
Cdd:COG3850 268 ---ALLLLLLASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELA 344
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 806950971 548 RLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAI 592
Cdd:COG3850 345 SILALQAALEAAAAGAALAAAAAAAGLARALAQAGADAAEALGLL 389
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
404-468 |
3.63e-14 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 67.24 E-value: 3.63e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 806950971 404 RKEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDTLILDMLELAKFESG 468
Cdd:pfam00512 2 KSEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQREYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
404-468 |
3.93e-14 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 67.21 E-value: 3.93e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 806950971 404 RKEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDTLILDMLELAKFESG 468
Cdd:smart00388 2 KREFLANLSHELRTPLTAIRGYLELLLDTELSEEQREYLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
516-600 |
8.87e-14 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 67.90 E-value: 8.87e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 516 RIEQVIVNFLTNAIRYTPSKEDI-IISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISK 594
Cdd:cd16925 4 KYERVVLNLLSNAFKFTPDGGRIrCILEKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGLGLSIVK 83
|
....*.
gi 806950971 595 NILELH 600
Cdd:cd16925 84 EFVELH 89
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
513-612 |
9.05e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 67.49 E-value: 9.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 513 NQGRIEQVIVNFLTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARqRSQGGTGLGLAI 592
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSR-RSGGHYGMGLYI 79
|
90 100
....*....|....*....|
gi 806950971 593 SKNILELHEVEYGVKNTEDG 612
Cdd:cd16975 80 AKNLVEKHGGSLIIENSQKG 99
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
391-594 |
1.10e-13 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 74.50 E-value: 1.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 391 EEDIEKERKLEKTR--KEFISGVSHELKTPLSimkSCIS----ILKDGVAEHKKEYyFQAMEREVDKMDTLILDMLELAK 464
Cdd:PRK11107 278 ELDLAKKRAQEAARikSEFLANMSHELRTPLN---GVIGftrqTLKTPLTPTQRDY-LQTIERSANNLLAIINDILDFSK 353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 465 FESGtyKMKMDS--FYIDTVMEDICEHLSVEIEKKELR----VHKNIgPFEVVANQGRIEQVIVNFLTNAIRYTPSKE-D 537
Cdd:PRK11107 354 LEAG--KLVLENipFSLRETLDEVVTLLAHSAHEKGLEltlnIDPDV-PDNVIGDPLRLQQIITNLVGNAIKFTESGNiD 430
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 538 IIISTI---DERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISK 594
Cdd:PRK11107 431 ILVELRalsNTKVQLEVQIRDTGIGISERQQSQLFQAFRQADASISRRHGGTGLGLVITQ 490
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
322-612 |
1.95e-13 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 71.92 E-value: 1.95e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 322 FVVVLIFLASFYYSKQIAKPLLKINDTTKKiAHLDFTEKIPITSK-DEIGDLSKNINVLsnklnshIGQLEEDIEKERkl 400
Cdd:PRK10755 69 VMVSLTLLICFQAVRWITRPLAELQKELEA-RTADNLTPIAIHSStLEIEAVTSALNQL-------VSRLTSTLDQER-- 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 401 ektrkEFISGVSHELKTPLSimkscisilkdGVAEH----KKEYYFQAM---EReVDKMDTLILDMLELA----KFESGT 469
Cdd:PRK10755 139 -----LFTADVAHELRTPLA-----------GIRLHlellEKQHHIDVApliAR-LDQMMHTVEQLLQLAragqSFSSGH 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 470 YK-MKMDSFYIDTVMEDICEHLsvEIEKKELRVHKNIGPFEVVANQGRIEQVIVNFLTNAIRYTPSKEDIIISTIDERNR 548
Cdd:PRK10755 202 YQtVKLLEDVILPSQDELSEML--EQRQQTLLLPESAADITVQGDATLLRLLLRNLVENAHRYSPEGSTITIKLSQEDGG 279
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 806950971 549 LKVCIENKGTHIEEEQLDKIWDRFYRVDaarQRSqGGTGLGLAISKNILELHEVEYGVKNTEDG 612
Cdd:PRK10755 280 AVLAVEDEGPGIDESKCGELSKAFVRMD---SRY-GGIGLGLSIVSRITQLHHGQFFLQNRQER 339
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
393-598 |
5.30e-13 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 72.46 E-value: 5.30e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 393 DIEKERKLEKT--RKEFISGVSHELKTPLSIMKSCISILK-DGVAEHKKEYYFQAMEREVDKMDTLILDMLELAKFESGT 469
Cdd:PRK09959 699 EVERNKAINATvaKSQFLATMSHEIRTPISSIMGFLELLSgSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGN 778
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 470 YKMKMDSFYIDTVMEDICEHLSVEIEKKELRVH-KNIGP--FEVVANQGRIEQVIVNFLTNAIRYTPSKEDIIISTI--- 543
Cdd:PRK09959 779 YQLQPQWVDIPTLVQNTCHSFGAIAASKSIALScSSTFPdhYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLghi 858
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 806950971 544 -DERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQrsQGGTGLGLAISKNILE 598
Cdd:PRK09959 859 dDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQ--QTGSGLGLMICKELIK 912
|
|
| ArsS_fam_HK |
NF038389 |
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase ... |
239-603 |
1.01e-12 |
|
ArsS family sensor histidine kinase; ArsS in Helicobacter pylori is a sensor histidine kinase participating in a two-component system that controls the response to acid conditiions encountered during the process of gastric colonization. This HMM identified ArsS itself but also a broader collection of apparent orthologs from closely related non-gastric colonizers such as Helicobacter hepaticus, Campylobacter jejuni and Wolinella succinogenes. See BlastRule NBR014349 for specific identification of ArsS itself, distinguished by a signature His residue that becomes protonated at low pH.
Pssm-ID: 468500 [Multi-domain] Cd Length: 402 Bit Score: 70.26 E-value: 1.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 239 YKNTLFLDSIKEFQTDVVLKESNQIEYSTKTMDYEKNDIKYKLLMKP-----------------IKEKDGSVTYiyamas 301
Cdd:NF038389 47 TLLQLYQKNINEEELEKYLKNFGFMPITDKKLEKEILEIGKNKFILKengsfrilkyndkiyllIKNDGFSLLL------ 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 302 lqpVDEAVQMVQDYYIYIIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKninvlsn 381
Cdd:NF038389 121 ---EDNEKKSYRYYYIIVFFIFLILLLLILYISVLKSLKPLKKLKKQIKKFANGDFDFIKSESNGDEIGEVAN------- 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 382 klnshigQLEEDIEKERKLEKTRKEFISGVSHELKTPlsIMKSCI--SILKDGvaEHKKEyyfqaMEREVDKMDTLIldm 459
Cdd:NF038389 191 -------EFDKAVKKIKALNESRQLFLRNIMHELKTP--ITKGRIvaEMLEDE--KQKER-----LISIFERLESLI--- 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 460 LELAKFE---SGTYKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNIgpFEVVANQGRIEQVIVNFLTNAIRYTPSKE 536
Cdd:NF038389 252 NEFAKIEqltSKNYKLNKKEYRLSDIIDEAIDMLMIDDSSVIIKVSLED--FKLNVDFELFSLAIKNLIDNAIKYSPDKK 329
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 806950971 537 DIIISTIDernrlKVCIENKGTHIEEEqLDKIWDRFYRvdaARQRSQGGTGLGLAISKNILELHEVE 603
Cdd:NF038389 330 VTIEIKGD-----KIEFKNKGEPLEEP-LEYYFEPFFK---GNEKSKSGFGLGLYIVKNILKAHGFK 387
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
401-464 |
1.27e-12 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 63.00 E-value: 1.27e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 806950971 401 EKTRKEFISGVSHELKTPLSIMKSCISILKDGVAEHKK-EYYFQAMEREVDKMDTLILDMLELAK 464
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEqREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
517-600 |
1.52e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 63.99 E-value: 1.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIVNFLTNAIRYTPSKedIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNI 596
Cdd:cd16939 1 MARALDNLLRNALRYAHRT--VRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGLGLAIVHRV 78
|
....
gi 806950971 597 LELH 600
Cdd:cd16939 79 ALWH 82
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
517-614 |
3.27e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 62.85 E-value: 3.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIVNFLTNAIRYtpSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAArqRSQGGTGLGLAISKNI 596
Cdd:cd16950 1 LKRVLSNLVDNALRY--GGGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNA--RGTSGTGLGLAIVQRI 76
|
90
....*....|....*...
gi 806950971 597 LELHEVEYGVKNTEDGVL 614
Cdd:cd16950 77 SDAHGGSLTLANRAGGGL 94
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
393-594 |
5.49e-12 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 68.81 E-value: 5.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 393 DIeKERK-----LEKTRKE---FISGVSHELKTPLSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDTLILDMLELAK 464
Cdd:PRK11091 265 DI-TERKryqdaLEKASRDkttFISTISHELRTPLNGIVGLSRILLDTELTAEQRKYLKTIHVSAITLGNIFNDIIDMDK 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 465 FESgtYKMKMDSFYIDTV--MEDIcEHLS-VEIEKKELRVHKNIG---PFEVVANQGRIEQVIVNFLTNAIRYTPsKEDI 538
Cdd:PRK11091 344 MER--RKLQLDNQPIDFTdfLADL-ENLSgLQAEQKGLRFDLEPLlplPHKVITDGTRLRQILWNLISNAVKFTQ-QGGV 419
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 806950971 539 IISTI-DERNRLKVCIENKGTHIEEEQLDKIWDRFYRV-DAARQRSQGGTGLGLAISK 594
Cdd:PRK11091 420 TVRVRyEEGDMLTFEVEDSGIGIPEDELDKIFAMYYQVkDSHGGKPATGTGIGLAVSK 477
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
517-614 |
6.01e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 62.48 E-value: 6.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIVNFLTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVdAARQRSQGGTGLGLAISKNI 596
Cdd:cd16945 5 LRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSL-PRPHSGQKSTGLGLAFVQEV 83
|
90
....*....|....*...
gi 806950971 597 LELHEVEYGVKNTEDGVL 614
Cdd:cd16945 84 AQLHGGRITLRNRPDGVL 101
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
519-600 |
9.54e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 62.20 E-value: 9.54e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 519 QVIVNFLTNAIRYTPSKE-DIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNIL 597
Cdd:cd16953 3 QVLRNLIGNAISFSPPDTgRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYTERPANEAFGQHSGLGLSISRQII 82
|
...
gi 806950971 598 ELH 600
Cdd:cd16953 83 EAH 85
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
517-600 |
1.64e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 61.28 E-value: 1.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIVNFLTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQrsqgGTGLGLAISKNI 596
Cdd:cd16943 4 LNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPVGE----GTGLGLSLSYRI 79
|
....
gi 806950971 597 LELH 600
Cdd:cd16943 80 IQKH 83
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
243-607 |
3.43e-11 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 65.81 E-value: 3.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 243 LFLDSIKEFQTDVVLKESNQIEYSTKTMDYEKNDIKYKLLMKPIKEKDGSVTYIYAMASLQPVDEAVQMVQDYYIYIIAF 322
Cdd:COG2972 86 LLLLLLLLILLLSLLLLLALILLLALLLLLSILLLILGLLLIILLLLSLLGWTLVSLIPKSELFRGLFSLRRLILLIILL 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 323 VVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTeKIPITSKDEIGDLSKNINVLSNKLNSHIGQLEEDIEKERKLEk 402
Cdd:COG2972 166 LLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLV-RLEVSGNDEIGILARSFNEMVERIKELIEEVYELELEKKEAE- 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 403 trkefisgvshelktpLSIMKSCI----------SIlkdgvaehkkeyYFQAMEREVDKMDTLILDMLELAKfesgtYKM 472
Cdd:COG2972 244 ----------------LKALQAQInphflfntlnSI------------RWLAELEDPEEAEEMLEALSKLLR-----YSL 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 473 KMDSFYIdTVME--DICEHLsVEIEK----KELRVHKNIGPfevvanqgRIEQVIVNFLT------NAIRY--TPSKED- 537
Cdd:COG2972 291 SKGDELV-TLEEelELIKSY-LEIQKlrfgDRLEVEIEIDE--------ELLDLLIPKLIlqplveNAIEHgiEPKEGGg 360
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 806950971 538 -IIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFyrvdaarQRSQGGTGLGLAISKNILELH-EVEYGVK 607
Cdd:COG2972 361 tIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEEL-------SSKGEGRGIGLRNVRERLKLYyGEEYGLE 425
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
407-592 |
5.54e-11 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 65.77 E-value: 5.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 407 FISGVSHELKTPLSIMKSCISILKDgvaehkkeyyfQAMEREVDKMDT-----------LILDMLELAKFESGTYKMKMD 475
Cdd:PRK10841 450 FLATVSHELRTPLYGIIGNLDLLQT-----------KELPKGVDRLVTamnnssslllkIISDILDFSKIESEQLKIEPR 518
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 476 SFYIDTVMEDICEHLSVEIEKKELRVHKNIGPFEVVANQG---RIEQVIVNFLTNAIRYTPSKEDIIISTIDErNRLKVC 552
Cdd:PRK10841 519 EFSPREVINHITANYLPLVVKKRLGLYCFIEPDVPVALNGdpmRLQQVISNLLSNAIKFTDTGCIVLHVRVDG-DYLSFR 597
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 806950971 553 IENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAI 592
Cdd:PRK10841 598 VRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAI 637
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
379-612 |
5.99e-11 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 65.06 E-value: 5.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 379 LSNKLNSHIGQLEEDIEKERKlektrkeFISGVSHELKTPLSIMKscisiLKDGVA------EHKKEYYFQAMEREVDKM 452
Cdd:PRK10337 219 LVEALNQLFARTHAMMVRERR-------FTSDAAHELRSPLAALK-----VQTEVAqlsdddPQARKKALLQLHAGIDRA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 453 DTLILDMLELAKFES-----GTYKMKMDSFYIDTVMeDICEHlsVEIEKKELRVHKNIGPfevVANQGR---IEQVIVNF 524
Cdd:PRK10337 287 TRLVDQLLTLSRLDSldnlqDVAEIPLEDLLQSAVM-DIYHT--AQQAGIDVRLTLNAHP---VIRTGQpllLSLLVRNL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 525 LTNAIRYTPSKEDIIIsTIDERnRLKVciENKGTHIEEEQLDKIWDRFYRVDAarqRSQGGTGLGLAISKNILELHEVEY 604
Cdd:PRK10337 361 LDNAIRYSPQGSVVDV-TLNAR-NFTV--RDNGPGVTPEALARIGERFYRPPG---QEATGSGLGLSIVRRIAKLHGMNV 433
|
....*...
gi 806950971 605 GVKNTEDG 612
Cdd:PRK10337 434 SFGNAPEG 441
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
501-598 |
7.10e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 59.83 E-value: 7.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 501 VHKNI--GPFEVVANQGRIEQVIVNFLTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAA 578
Cdd:cd16947 3 VEINIpdRPIYANANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDS 82
|
90 100
....*....|....*....|
gi 806950971 579 RQRSQGGTGLGLAISKNILE 598
Cdd:cd16947 83 RNSAKQGNGLGLTITKRLAE 102
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
517-619 |
1.78e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 58.18 E-value: 1.78e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIVNFLTNAIR----YTPSKEDIIIS-TIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAArqrsqgGTGLGLA 591
Cdd:cd16920 1 IQQVLINLVRNGIEamseGGCERRELTIRtSPADDRAVTISVKDTGPGIAEEVAGQLFDPFYTTKSE------GLGMGLS 74
|
90 100
....*....|....*....|....*....
gi 806950971 592 ISKNILELHEVEYGV-KNTEDGVLFYFYL 619
Cdd:cd16920 75 ICRSIIEAHGGRLSVeSPAGGGATFQFTL 103
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
305-392 |
1.91e-10 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 63.50 E-value: 1.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 305 VDEAVQMVQDYYIYIIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKNINVLSNKLN 384
Cdd:COG0840 173 ALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRMIENLR 252
|
....*...
gi 806950971 385 SHIGQLEE 392
Cdd:COG0840 253 ELVGQVRE 260
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
517-619 |
2.24e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 58.11 E-value: 2.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIVNFLTNAIRYTPSKE--DIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAarQRSQGGTGLGLAISK 594
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPRRppRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFGIFQRLHS--REEYEGTGVGLAIVR 78
|
90 100
....*....|....*....|....*.
gi 806950971 595 NILELHEVEYGVKNTED-GVLFYFYL 619
Cdd:cd16921 79 KIIERHGGRIWLESEPGeGTTFYFTL 104
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
340-383 |
3.21e-10 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 55.53 E-value: 3.21e-10
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 806950971 340 KPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKNINVLSNKL 383
Cdd:cd06225 2 RPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
|
|
| HAMP |
pfam00672 |
HAMP domain; |
334-384 |
5.05e-09 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 52.24 E-value: 5.05e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 806950971 334 YSKQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKNINVLSNKLN 384
Cdd:pfam00672 2 LARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLR 52
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
336-388 |
6.35e-09 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 52.25 E-value: 6.35e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 806950971 336 KQIAKPLLKINDTTKKIAHLDFTEKIPITSKDEIGDLSKNINVLSNKLNSHIG 388
Cdd:smart00304 1 RRLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
311-598 |
2.32e-08 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 56.95 E-value: 2.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 311 MVQDYYIYIIA----FVVVLIFLASfYYSkqiakpLLKINDTTKKIAHLD--FTEKIPITSKDEIGDLSKNINVLsnkLN 384
Cdd:PRK10815 188 MVWSWFSYVLLanllLVIPLLWLAA-WWS------LRPIEALAKQVRELEegEREQLDPNPPRELTSLVRNLNRL---LK 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 385 ShigqleediEKERkLEKTRKEfISGVSHELKTPLSIMKSCISILKDGvaehKKEYYFQA---MEREVDKMDTLILDMLE 461
Cdd:PRK10815 258 N---------ERER-YTKYRTT-LTDLTHSLKTPLAVLQSTLRSLRSG----KQMSVEQAepiMLEQISRISQQIGYYLH 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 462 LAKFESGTYKMKMDSFYIDTVMEDICEHLSVEIEKKELRVHKNIGPfEV--VANQGRIEQVIVNFLTNAIRYTpsKEDII 539
Cdd:PRK10815 323 RASMRSEHNLLSRELHSVAPLLDNLTSALNKVYQRKGVNITLDISP-EItfVGEKNDFMEVMGNVLDNACKYC--LEFVE 399
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 806950971 540 ISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQrsqgGTGLGLAISKNILE 598
Cdd:PRK10815 400 ISARQTDEHLHIVVEDDGPGIPESKRELIFDRGQRADTLRP----GQGLGLSVAREITE 454
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
405-619 |
4.83e-08 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 55.47 E-value: 4.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 405 KEFISGVSHELKTPLSIMKSCISILKDGVAEHKKEYYFQAMEREVDKMDTLIlDMLeLAKFESGTYKMKMdsfyIDTVME 484
Cdd:PRK11073 131 RDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALTEYTKVIIEQADRLRNLV-DRL-LGPQRPGTHVTES----IHKVAE 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 485 DICEHLSVEIEKKeLRVHKNIGP----FEVVANQgrIEQVIVNFLTNAIR-YTPSKEDIIISTID--------ERNRL-- 549
Cdd:PRK11073 205 RVVQLVSLELPDN-VRLIRDYDPslpeLAHDPDQ--IEQVLLNIVRNALQaLGPEGGTITLRTRTafqltlhgERYRLaa 281
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 806950971 550 KVCIENKGTHIEEEQLDKIwdrFYRVDAARQrsqGGTGLGLAISKNILELH----EVEYGVKNTEdgvlFYFYL 619
Cdd:PRK11073 282 RIDIEDNGPGIPPHLQDTL---FYPMVSGRE---GGTGLGLSIARNLIDQHsgkiEFTSWPGHTE----FSVYL 345
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
484-598 |
2.67e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 49.94 E-value: 2.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 484 EDICEHLSVEIEKKELRVHKNIGP-FEVVANQGRIEQVIVNFLTNAIRYtpSKEDIIISTIDERNRLKVCIENKGTHIEE 562
Cdd:cd16954 4 DSLCSALNKVYQRKGVSISLDISPeLRFPGERNDLMELLGNLLDNACKW--CLEFVEVTARQTDGGLHLIVDDDGPGVPE 81
|
90 100 110
....*....|....*....|....*....|....*.
gi 806950971 563 EQLDKIWDRFYRVDAARQrsqgGTGLGLAISKNILE 598
Cdd:cd16954 82 SQRSKIFQRGQRLDEQRP----GQGLGLAIAKEIVE 113
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
517-596 |
1.48e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 47.28 E-value: 1.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIvnflTNAIRYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAARQrSQGGTGLGLAISKNI 596
Cdd:cd16948 10 IGQIV----SNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRN-FQESTGMGLYLVKKL 84
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
517-612 |
2.01e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 46.68 E-value: 2.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIVNFLTNAIRYTPSKED--IIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVdaarqRSQG-GTGLGLAIS 593
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKVENprIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTT-----KPVGkGTGLGLSIS 75
|
90
....*....|....*....
gi 806950971 594 KNILELHEVEYGVKNTEDG 612
Cdd:cd16976 76 YGIVEEHGGRLSVANEEGA 94
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
517-600 |
5.55e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 42.52 E-value: 5.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIVNFLTNAI-----RYTPSKEDIIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVDAArqrsqgGTGLGLA 591
Cdd:cd16944 5 ISQVLTNILKNAAeaiegRPSDVGEVRIRVEADQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRPK------GTGLGLA 78
|
....*....
gi 806950971 592 ISKNILELH 600
Cdd:cd16944 79 IVKKIMEEH 87
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
517-600 |
5.94e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 42.77 E-value: 5.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 517 IEQVIVNFLTNAIRYTPSKE-DIIIST--------IDERNRL--KVCIENKGTHIEEEQLDKIwdrFYRVDAARQrsqGG 585
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSGgEIILRTrtqrqvtlGHPRHRLalRVSVIDNGPGIPPDLQDTI---FYPMVSGRE---NG 74
|
90
....*....|....*
gi 806950971 586 TGLGLAISKNILELH 600
Cdd:cd16918 75 TGLGLAIAQNIVSQH 89
|
|
| PRK10935 |
PRK10935 |
nitrate/nitrite two-component system sensor histidine kinase NarQ; |
317-405 |
2.91e-04 |
|
nitrate/nitrite two-component system sensor histidine kinase NarQ;
Pssm-ID: 236800 [Multi-domain] Cd Length: 565 Bit Score: 43.69 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 317 IYIIAFVVVliflasFYYSKQIAKPLLKINDTTKKIAHLDFTE-KIPITSKDEIGDLSKNINVLSNKLNSHIGQLEEDIE 395
Cdd:PRK10935 161 ILTLVFFTV------RFTRRQVVAPLNQLVTASQQIEKGQFDHiPLDTTLPNELGLLAKAFNQMSSELHKLYRSLEASVE 234
|
90
....*....|
gi 806950971 396 kerklEKTRK 405
Cdd:PRK10935 235 -----EKTRK 239
|
|
| HATPase_Phy-like |
cd16932 |
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana ... |
514-604 |
3.57e-04 |
|
Histidine kinase-like ATPase domain of plant phytochromes similar to Arabidopsis thaliana Phytochrome A, B, C, D and E; This family includes the histidine kinase-like ATPase (HATPase) domains of plant red/far-red photoreceptors, the phytochromes, and includes the Arabidopsis thaliana phytochrome family phyA-phyE. Following red light absorption, biologically inactive forms of phytochromes convert to active forms, which rapidly convert back to inactive forms upon far-red light irradiation. Phytochromes can be considered as having an N-terminal photosensory region to which a bilin chromophore is bound, and a C-terminal output region, which includes the HATPase domain represented here, and is involved in dimerization and presumably contributes to relaying the light signal to downstream signaling events.
Pssm-ID: 340409 [Multi-domain] Cd Length: 113 Bit Score: 40.33 E-value: 3.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 514 QGRIEQVIVNFLTNAIRYTPSKED-IIISTIDERNRLK-----VCIENKGTH----IEEEQLDKIWDrfyrvdaarqRSQ 583
Cdd:cd16932 4 QIRLQQVLADFLLNAVRFTPSPGGwVEIKVSPTKKQIGdgvhvIHLEFRITHpgqgLPEELVQEMFE----------ENQ 73
|
90 100
....*....|....*....|....*
gi 806950971 584 GGT--GLGLAISKNILELH--EVEY 604
Cdd:cd16932 74 WTTqeGLGLSISRKLVKLMngDVRY 98
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
355-601 |
7.22e-04 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 42.74 E-value: 7.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 355 LDFTEKIPITSKDEIGDLSKNINVLSNKLNshIGQLEEDIEK-ERKLEKTRK-----EFISGVSHELKTPLSIMKSCISI 428
Cdd:PRK13837 397 LGRQRYGLRPPAGELQLLELALDCLAHAIE--RRRLETERDAlERRLEHARRleavgTLASGIAHNFNNILGAILGYAEM 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 429 LKDGVAEHKK-EYYFQAMEREVDKMDTLILDMLELAKFESGTYKmkmdSFYIDTVMEDICEHLSVEI-EKKELRVHKNIG 506
Cdd:PRK13837 475 ALNKLARHSRaARYIDEIISAGARARLIIDQILAFGRKGERNTK----PFDLSELVTEIAPLLRVSLpPGVELDFDQDQE 550
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 507 PFEVVANQGRIEQVIVNFLTNAIRY--TPSKEDIIISTIDER-------------NRLKVCIENKGTHIEEEQLDKIWDR 571
Cdd:PRK13837 551 PAVVEGNPAELQQVLMNLCSNAAQAmdGAGRVDISLSRAKLRapkvlshgvlppgRYVLLRVSDTGAGIDEAVLPHIFEP 630
|
250 260 270
....*....|....*....|....*....|
gi 806950971 572 FYRVDAarqrsqGGTGLGLAISKNILELHE 601
Cdd:PRK13837 631 FFTTRA------GGTGLGLATVHGIVSAHA 654
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
523-619 |
1.32e-03 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 41.37 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 806950971 523 NFLTNAIRYTPSKED----IIISTIDERNRLKVCIENKGTHIEEEQLDKIWDRFYRVdaarqRSQGGTGLGLAISKNILE 598
Cdd:COG3290 288 NLLDNAIEAVEKLPEeerrVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFST-----KLGEGRGLGLALVKQIVE 362
|
90 100
....*....|....*....|...
gi 806950971 599 LH--EVEYGvKNTEDGVLFYFYL 619
Cdd:COG3290 363 KYggTIEVE-SEEGEGTVFTVRL 384
|
|
| |
