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Conserved domains on  [gi|815720218|ref|WP_046451758|]
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MULTISPECIES: energy transducer TonB [Parabacteroides]

Protein Classification

WG repeat-containing protein; SEL1-like repeat protein( domain architecture ID 10296422)

WG repeat-containing protein may form a beta solenoid structure| SEL1-like repeat family protein may function as an adaptor protein for the assembly of macromolecular complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TonB_C super family cl10048
Gram-negative bacterial TonB protein C-terminal; The TonB_C domain is the well-characterized ...
 408-455 6.18e-04

Gram-negative bacterial TonB protein C-terminal; The TonB_C domain is the well-characterized C-terminal region of the TonB receptor molecule. This protein is bound to an inner membrane-bound protein ExbB via a globular domain and has a flexible middle region that is likely to help in positioning the C-terminal domain into the iron-transporter barrel in the outer membrane. TonB_C interacts with the N-terminal TonB box of the outer membrane transporter that binds the Fe3+-siderophore complex. The barrel of the transporter, consisting of 22 beta-sheets and an inside plug, binds the iron complex in the barrel entrance.


The actual alignment was detected with superfamily member pfam03544:

Pssm-ID: 471968 [Multi-domain]  Cd Length: 79  Bit Score: 38.80  E-value: 6.18e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 815720218  408 KYPPKLQKKNREGMVYVTYKLDGNGYITNPQVISCNNRK-FKRAALNAF 455
Cdd:pfam03544   4 VYPEEARRRGIEGTVVVEFLIDPDGNVTNVRVVKSSGYSiLDEAALEAV 52
WG_beta_rep pfam14903
WG containing repeat; This repeat contains an N-terminal WG repeat motif. The extent of the ...
 604-635 5.07e-03

WG containing repeat; This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).


:

Pssm-ID: 464361 [Multi-domain]  Cd Length: 35  Bit Score: 35.11  E-value: 5.07e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 815720218  604 GFADSLGNVIIEPQFKFAYPFKGGKTKATLKG 635
Cdd:pfam14903   2 GYIDKKGKIVIPPKYDEAGPFSEGLAAVKKNG 33
 
Name Accession Description Interval E-value
TonB_C pfam03544
Gram-negative bacterial TonB protein C-terminal; The TonB_C domain is the well-characterized ...
 408-455 6.18e-04

Gram-negative bacterial TonB protein C-terminal; The TonB_C domain is the well-characterized C-terminal region of the TonB receptor molecule. This protein is bound to an inner membrane-bound protein ExbB via a globular domain and has a flexible middle region that is likely to help in positioning the C-terminal domain into the iron-transporter barrel in the outer membrane. TonB_C interacts with the N-terminal TonB box of the outer membrane transporter that binds the Fe3+-siderophore complex. The barrel of the transporter, consisting of 22 beta-sheets and an inside plug, binds the iron complex in the barrel entrance.


Pssm-ID: 427361 [Multi-domain]  Cd Length: 79  Bit Score: 38.80  E-value: 6.18e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 815720218  408 KYPPKLQKKNREGMVYVTYKLDGNGYITNPQVISCNNRK-FKRAALNAF 455
Cdd:pfam03544   4 VYPEEARRRGIEGTVVVEFLIDPDGNVTNVRVVKSSGYSiLDEAALEAV 52
TonB COG0810
Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope ...
 410-454 9.75e-04

Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440572 [Multi-domain]  Cd Length: 70  Bit Score: 37.95  E-value: 9.75e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 815720218 410 PPKLQKKNREGMVYVTYKLDGNGYITNPQVI-SCNNRKFKRAALNA 454
Cdd:COG0810    1 PEEARRRGIEGTVTVRFTIDADGRVTDVEVVkSSGHPLLDEAALRA 46
WG_beta_rep pfam14903
WG containing repeat; This repeat contains an N-terminal WG repeat motif. The extent of the ...
 604-635 5.07e-03

WG containing repeat; This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).


Pssm-ID: 464361 [Multi-domain]  Cd Length: 35  Bit Score: 35.11  E-value: 5.07e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 815720218  604 GFADSLGNVIIEPQFKFAYPFKGGKTKATLKG 635
Cdd:pfam14903   2 GYIDKKGKIVIPPKYDEAGPFSEGLAAVKKNG 33
 
Name Accession Description Interval E-value
TonB_C pfam03544
Gram-negative bacterial TonB protein C-terminal; The TonB_C domain is the well-characterized ...
 408-455 6.18e-04

Gram-negative bacterial TonB protein C-terminal; The TonB_C domain is the well-characterized C-terminal region of the TonB receptor molecule. This protein is bound to an inner membrane-bound protein ExbB via a globular domain and has a flexible middle region that is likely to help in positioning the C-terminal domain into the iron-transporter barrel in the outer membrane. TonB_C interacts with the N-terminal TonB box of the outer membrane transporter that binds the Fe3+-siderophore complex. The barrel of the transporter, consisting of 22 beta-sheets and an inside plug, binds the iron complex in the barrel entrance.


Pssm-ID: 427361 [Multi-domain]  Cd Length: 79  Bit Score: 38.80  E-value: 6.18e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 815720218  408 KYPPKLQKKNREGMVYVTYKLDGNGYITNPQVISCNNRK-FKRAALNAF 455
Cdd:pfam03544   4 VYPEEARRRGIEGTVVVEFLIDPDGNVTNVRVVKSSGYSiLDEAALEAV 52
TonB COG0810
Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope ...
 410-454 9.75e-04

Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440572 [Multi-domain]  Cd Length: 70  Bit Score: 37.95  E-value: 9.75e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 815720218 410 PPKLQKKNREGMVYVTYKLDGNGYITNPQVI-SCNNRKFKRAALNA 454
Cdd:COG0810    1 PEEARRRGIEGTVTVRFTIDADGRVTDVEVVkSSGHPLLDEAALRA 46
WG_beta_rep pfam14903
WG containing repeat; This repeat contains an N-terminal WG repeat motif. The extent of the ...
 604-635 5.07e-03

WG containing repeat; This repeat contains an N-terminal WG repeat motif. The extent of the repeat is poorly defined. This repeat may form a beta solenoid structure (Bateman A pers. obs.).


Pssm-ID: 464361 [Multi-domain]  Cd Length: 35  Bit Score: 35.11  E-value: 5.07e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 815720218  604 GFADSLGNVIIEPQFKFAYPFKGGKTKATLKG 635
Cdd:pfam14903   2 GYIDKKGKIVIPPKYDEAGPFSEGLAAVKKNG 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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