|
Name |
Accession |
Description |
Interval |
E-value |
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
1-440 |
4.31e-129 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 381.10 E-value: 4.31e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 1 MPRARYKNLVDTFAEDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFVREISLPPGQGSG 80
Cdd:COG1167 9 SSGPLYLQLADALREAILSGRLPPGDRLPSSRELAAQLGVSRSTVVRAYEELEAEGLIESRPGSGTFVAARLPAPAPAPR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 81 Q------------MNVAPGMLDLNFNYPS---LPgqAELLRTALRQLALSGDLQaLLRYQPHAGRQHERAAVARHLLSRG 145
Cdd:COG1167 89 AaaavaapalrrlLEAAPGVIDLGSGAPDpdlFP--LAALRRALRRALRRLPPA-LLGYGDPQGLPELREAIARYLARRG 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 146 LTVEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAIPLTASGPDLDHLHSLCRKHPVRAV 225
Cdd:COG1167 166 VPASPDQILITSGAQQALDLALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPVPVDEDGLDLDALEAALRRHRPRAV 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 226 YSMPTVHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLA--EHAPPPLATL-APERTVYVGGFSKSVATGLRVGFV 302
Cdd:COG1167 246 YVTPSHQNPTGATMSLERRRALLELARRHGVPIIEDDYDSELRydGRPPPPLAALdAPGRVIYIGSFSKTLAPGLRLGYL 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 303 SAPAAWVKALERSIMATTWNVPGVMSAIAVAWLDDGTVAQLEAQKRQDARARQALAAQVLK-----GLTYISHPSSYFLW 377
Cdd:COG1167 326 VAPGRLIERLARLKRATDLGTSPLTQLALAEFLESGHYDRHLRRLRREYRARRDLLLAALArhlpdGLRVTGPPGGLHLW 405
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 817117913 378 LPLAEEARADQIAMTLQRENIAVSTAEPFAVSAHVPHALRLALGSVDMTALREALLAVRKVVA 440
Cdd:COG1167 406 LELPEGVDAEALAAAALARGILVAPGSAFSADGPPRNGLRLGFGAPSEEELEEALRRLAELLR 468
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
89-432 |
9.56e-59 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 196.02 E-value: 9.56e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 89 LDLNFNYPSLPGQAELLRTALRQLALSGDLQallrYQPHAGRQHERAAVARHL-LSRGLTVEADQVLLVSGAQHGLAVTL 167
Cdd:cd00609 1 IDLSIGEPDFPPPPEVLEALAAAALRAGLLG----YYPDPGLPELREAIAEWLgRRGGVDVPPEEIVVTNGAQEALSLLL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 168 MALLKPGDVIAVDALTYSGFKVLAETLHLEMLAIPLTASGPDLDHLHSL--CRKHPVRAVYSMPtVHNPLGWVMSLEQRE 245
Cdd:cd00609 77 RALLNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGFLLDLELLeaAKTPKTKLLYLNN-PNNPTGAVLSEEELE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 246 HLVAIARQHNLMIIEDAAYAFLA---EHAPPPLATLAPERTVYVGGFSKSVA-TGLRVGFVSAPAAWVKALERSIMATTW 321
Cdd:cd00609 156 ELAELAKKHGILIISDEAYAELVydgEPPPALALLDAYERVIVLRSFSKTFGlPGLRIGYLIAPPEELLERLKKLLPYTT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 322 NVPGVMSAIAVAWLDDGTVAQLEA-----QKRQDARARQALAaqvLKGLTYISHPSSYFLWLPLAEEARADQIAMTLQRE 396
Cdd:cd00609 236 SGPSTLSQAAAAAALDDGEEHLEElreryRRRRDALLEALKE---LGPLVVVKPSGGFFLWLDLPEGDDEEFLERLLLEA 312
|
330 340 350
....*....|....*....|....*....|....*...
gi 817117913 397 NIAVSTAEPFAVSAhvPHALRLALGSV--DMTALREAL 432
Cdd:cd00609 313 GVVVRPGSAFGEGG--EGFVRLSFATPeeELEEALERL 348
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
86-432 |
6.06e-38 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 141.81 E-value: 6.06e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 86 PGMLDLNFNYPSLPGqAELLRTALRQLALSGDLQallrYQPHAGRQHERAAVARHLLSR-GLTVEADQVLLVSGAQHGLA 164
Cdd:COG0436 30 EDVIDLGIGEPDFPT-PDHIREAAIEALDDGVTG----YTPSAGIPELREAIAAYYKRRyGVDLDPDEILVTNGAKEALA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 165 VTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAIPLTASG---PDLDHLHSLCRKHPvRA-VYSMPtvHNPLGWVMS 240
Cdd:COG0436 105 LALLALLNPGDEVLVPDPGYPSYRAAVRLAGGKPVPVPLDEENgflPDPEALEAAITPRT-KAiVLNSP--NNPTGAVYS 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 241 LEQREHLVAIARQHNLMIIEDAAYAFLA--EHAPPPLATL--APERTVYVGGFSKSVA-TGLRVGFVSAPAAWVKALERS 315
Cdd:COG0436 182 REELEALAELAREHDLLVISDEIYEELVydGAEHVSILSLpgLKDRTIVINSFSKSYAmTGWRIGYAVGPPELIAALLKL 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 316 IMATTWNVPGVMSAIAVAWLDDGT--VAQLEA--QKRQDararqalaaQVLKGLT----YISHPS-SYFLWLPLAEEAR- 385
Cdd:COG0436 262 QSNLTSCAPTPAQYAAAAALEGPQdyVEEMRAeyRRRRD---------LLVEGLNeiglSVVKPEgAFYLFADVPELGLd 332
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 817117913 386 ADQIAMTL-QRENIAVSTAEPFavSAHVPHALRLALgSVDMTALREAL 432
Cdd:COG0436 333 SEEFAERLlEEAGVAVVPGSAF--GPAGEGYVRISY-ATSEERLEEAL 377
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
86-432 |
6.83e-34 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 130.12 E-value: 6.83e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 86 PGMLDLNFNYPSLpgqaELLRTALRQLALSGDLQALLRYQPHAGRQHERAAVARHLLSRGLTVE--ADQVLLVSGAQHGL 163
Cdd:pfam00155 1 TDKINLGSNEYLG----DTLPAVAKAEKDALAGGTRNLYGPTDGHPELREALAKFLGRSPVLKLdrEAAVVFGSGAGANI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 164 AVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAIPLTAS---GPDLDHLHSLCRKhPVRAVYsMPTVHNPLGWVMS 240
Cdd:pfam00155 77 EALIFLLANPGDAILVPAPTYASYIRIARLAGGEVVRYPLYDSndfHLDFDALEAALKE-KPKVVL-HTSPHNPTGTVAT 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 241 LEQREHLVAIARQHNLMIIEDAAYA---FLAEHAPPPLATLAPE-RTVYVGGFSKS-VATGLRVGFVSAPAAWVKALERs 315
Cdd:pfam00155 155 LEELEKLLDLAKEHNILLLVDEAYAgfvFGSPDAVATRALLAEGpNLLVVGSFSKAfGLAGWRVGYILGNAAVISQLRK- 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 316 iMATTWNVPGVMSAIAVAWLDDgtvAQLEAQKRQDARARQALAAQVLK------GLTYISHPSSYFLWLPLAEEARADQI 389
Cdd:pfam00155 234 -LARPFYSSTHLQAAAAAALSD---PLLVASELEEMRQRIKERRDYLRdglqaaGLSVLPSQAGFFLLTGLDPETAKELA 309
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 817117913 390 AMTLQRENIAVSTAEPFavsaHVPHALRLALGSVDMTALREAL 432
Cdd:pfam00155 310 QVLLEEVGVYVTPGSSP----GVPGWLRITVAGGTEEELEELL 348
|
|
| PRK15481 |
PRK15481 |
transcriptional regulatory protein PtsJ; Provisional |
17-429 |
7.52e-25 |
|
transcriptional regulatory protein PtsJ; Provisional
Pssm-ID: 185378 [Multi-domain] Cd Length: 431 Bit Score: 105.90 E-value: 7.52e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 17 IRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFVREISLPPGQGSGQMNVApgMLDL---NF 93
Cdd:PRK15481 18 IQAGRLRPGDSLPPVRELASELGVNRNTVAAAYKRLVTAGLAQSQGRNGTVIRGSPSPVALEGGDPGTP--LHDLaggNP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 94 NYPSLPGQAELLRTALRQLALSGDlqallryqphAGRQHERAAVARHLLSRGLTVEADqVLLVSGAQHGLAVTLMALLKP 173
Cdd:PRK15481 96 DPQRLPDLSRYFARLSRTPRLYGD----------APVSPELHAWAARWLRDDCPVAFE-IDLTSGAIDAIERLLCAHLLP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 174 GDVIAVDALTYSGFKVLAETLHLEMLAIPLTASGPDLDHLHSLCRKHpVRAVYSMPTVHNPLGWVMSLEQREHLVAI-AR 252
Cdd:PRK15481 165 GDSVAVEDPCFLSSINMLRYAGFSASPVSVDAEGMQPEKLERALAQG-ARAVILTPRAHNPTGCSLSARRAAALRNLlAR 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 253 QHNLMIIEDAAYAFLAEHAPPPLATLAPERTVYVGGFSKSVATGLRVGFVSAPAAWVKALE-RSIMATTWnVPGVMSAIA 331
Cdd:PRK15481 244 YPQVLVIIDDHFALLSSSPYHSVIPQTTQRWALIRSVSKALGPDLRLAFVASDSATSARLRlRLNSGTQW-VSHLLQDLV 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 332 VAWLDDGTVAQLEAQKRQDARARQALAAQVLK--GLTYISHPSSYFLWLPLAEEARAdqIAMTLQRENIAVSTAEPFAVS 409
Cdd:PRK15481 323 YACLTDPEYQARLAQARLFYAQRRQKLARALQqyGIAIPSPGDGLNLWLPLDTDSQA--TALTLAKSGWLVREGEAFGVS 400
|
410 420
....*....|....*....|
gi 817117913 410 AHVpHALRLALGSVDMTALR 429
Cdd:PRK15481 401 APS-HGLRITLSTLNDAEIN 419
|
|
| HisC |
COG0079 |
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid ... |
74-435 |
2.14e-24 |
|
Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase [Amino acid transport and metabolism]; Histidinol-phosphate/aromatic aminotransferase or cobyric acid decarboxylase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 439849 [Multi-domain] Cd Length: 341 Bit Score: 103.29 E-value: 2.14e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 74 PPGQGSGQMNVAPGMLDLNFN---YPSLPGQAELLRTALRQLAL--SGDLQALlryqphagrqheRAAVARHLlsrglTV 148
Cdd:COG0079 1 SPYVPGGPIEEPEDIIKLSSNenpYGPPPKVLEAIAAALDALNRypDPDATAL------------REALAEYY-----GV 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 149 EADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAIPLTAS-GPDLDHLHSLCRKHPvRAVYs 227
Cdd:COG0079 64 PPEQVLVGNGSDELIQLLARAFLGPGDEVLVPEPTFSEYPIAARAAGAEVVEVPLDEDfSLDLDALLAAITERT-DLVF- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 228 MPTVHNPLGWVMSLEQREHLVAIARQHNLMIIeDAAYA-FLAEhaPPPLATLAPE-------RTvyvggFSKSVAT-GLR 298
Cdd:COG0079 142 LCNPNNPTGTLLPREELEALLEALPADGLVVV-DEAYAeFVPE--EDSALPLLARypnlvvlRT-----FSKAYGLaGLR 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 299 VGFVSAPAAWVKALERsiMATTWNVPGVMSAIAVAWLDDG-----TVAQLEAQKRQdararqalAAQVLK--GLTYIshP 371
Cdd:COG0079 214 LGYAIASPELIAALRR--VRGPWNVNSLAQAAALAALEDRayleeTRARLRAERER--------LAAALRalGLTVY--P 281
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 817117913 372 S-SYFLWLPLAEeaRADQIAMTLQRENIAVstaEPFAvSAHVPHALRLALGSV-DMTALREALLAV 435
Cdd:COG0079 282 SqANFVLVRVPE--DAAELFEALLERGILV---RDFS-SFGLPDYLRITVGTPeENDRLLAALKEI 341
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
134-337 |
8.34e-21 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 93.65 E-value: 8.34e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 134 RAAVARHLLSR-GLTVEADQVLLVSGAQHGLAVTLMALLKPGD----------------------VIAVDALTYSGFKVL 190
Cdd:PRK05764 74 REAIAAKLKRDnGLDYDPSQVIVTTGAKQALYNAFMALLDPGDeviipapywvsypemvklaggvPVFVPTGEENGFKLT 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 191 AETLhlemlaipLTASGPdldhlhslcrkhPVRA-VYSMPtvHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFL-- 267
Cdd:PRK05764 154 VEQL--------EAAITP------------KTKAlILNSP--SNPTGAVYSPEELEAIADVAVEHDIWVLSDEIYEKLvy 211
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 817117913 268 --AEHAPPplATLAPE---RTVYVGGFSKSVA-TGLRVGFVSAPAAWVKALERSIMATTWNVPGVMSAIAVAWLDD 337
Cdd:PRK05764 212 dgAEFTSI--ASLSPElrdRTITVNGFSKAYAmTGWRLGYAAGPKELIKAMSKLQSHSTSNPTSIAQYAAVAALNG 285
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
87-350 |
2.42e-19 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 89.33 E-value: 2.42e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 87 GMLDLNFNYPSLPGQAELLRTALRQLAlSGDLQallrYQPHAGRQHERAAVARHLLSR-GLTVEAD-QVLLVSGAQHGLA 164
Cdd:PRK07777 25 GAVNLGQGFPDEDGPPEMLEAAQEAIA-GGVNQ----YPPGPGIPELRAAIAAQRRRRyGLEYDPDtEVLVTVGATEAIA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 165 VTLMALLKPGD-VIAVDAL--TYSGFKVLAetlHLEMLAIPLTASG----PDLDHLHSLCRKHpVRAVYsMPTVHNPLGW 237
Cdd:PRK07777 100 AAVLGLVEPGDeVLLIEPYydSYAAVIAMA---GAHRVPVPLVPDGrgfaLDLDALRAAVTPR-TRALI-VNSPHNPTGT 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 238 VMSLEQREHLVAIARQHNLMIIEDAAYAFL----AEHAppPLATLaP---ERTVYVGGFSKSVA-TGLRVGFVSAPAAWV 309
Cdd:PRK07777 175 VLTAAELAAIAELAVEHDLLVITDEVYEHLvfdgARHL--PLATL-PgmrERTVTISSAAKTFNvTGWKIGWACGPAPLI 251
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 817117913 310 KALER-----SIMATTWNVPGVMSAIAvawLDDGTVAQLEA--QKRQD 350
Cdd:PRK07777 252 AAVRAakqylTYVGGAPFQPAVAHALD---HEDAWVAALRDslQAKRD 296
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
124-350 |
2.69e-19 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 89.01 E-value: 2.69e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVARHLLSR-GLTVEA-DQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAI 201
Cdd:PRK07309 63 YTGMAGLLELRQAAADFVKEKyNLDYAPeNEILVTIGATEALSASLTAILEPGDKVLLPAPAYPGYEPIVNLVGAEIVEI 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 202 PLTASG----PDLDHLHSLCRKHPVRAV-YSMPTvhNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLAEHAPP--P 274
Cdd:PRK07309 143 DTTENDfvltPEMLEKAILEQGDKLKAViLNYPA--NPTGVTYSREQIKALADVLKKYDIFVISDEVYSELTYTGEPhvS 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 275 LATLAPERTVYVGGFSKSVA-TGLRVGFVSAPAAWVKALERS-----IMATTWNVPGVMSAIAVAwLDDGTVAQLEAQKR 348
Cdd:PRK07309 221 IAEYLPDQTILINGLSKSHAmTGWRIGLIFAPAEFTAQLIKShqylvTAATTMAQFAAVEALTNG-KDDALPMKKEYIKR 299
|
..
gi 817117913 349 QD 350
Cdd:PRK07309 300 RD 301
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
86-305 |
5.23e-18 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 85.16 E-value: 5.23e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 86 PGMLDLNFNYPSLPGQAELLRTALrQLALSGDLqallRYQPHAGRQHERAAVARHLLSR-GLTVEADQVLLVSGAQHGLA 164
Cdd:PRK06348 29 PDIIDLSLGDPDLITDESIINAAF-EDAKKGHT----RYTDSGGDVELIEEIIKYYSKNyDLSFKRNEIMATVGACHGMY 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 165 VTLMALLKPGDVIAVDALTYSGFK----------VLAETLHLEMLAIpltasgpDLDHLHSLCrKHPVRAVYsMPTVHNP 234
Cdd:PRK06348 104 LALQSILDPGDEVIIHEPYFTPYKdqiemvggkpIILETYEEDGFQI-------NVKKLEALI-TSKTKAII-LNSPNNP 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 817117913 235 LGWVMSLEQREHLVAIARQHNLMIIEDAAY-AFLAEHAPPPLATLA--PERTVYVGGFSKSVA-TGLRVGFVSAP 305
Cdd:PRK06348 175 TGAVFSKETLEEIAKIAIEYDLFIISDEVYdGFSFYEDFVPMATLAgmPERTITFGSFSKDFAmTGWRIGYVIAP 249
|
|
| WHTH_GntR |
cd07377 |
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ... |
5-69 |
4.89e-17 |
|
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.
Pssm-ID: 153418 [Multi-domain] Cd Length: 66 Bit Score: 75.18 E-value: 4.89e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 817117913 5 RYKNLVDTFAEDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFVR 69
Cdd:cd07377 2 LYEQIADQLREAILSGELKPGDRLPSERELAEELGVSRTTVREALRELEAEGLVERRPGRGTFVA 66
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
124-349 |
7.26e-17 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 81.91 E-value: 7.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVARHLLSR-GLTVEADQVLLVSGAQHGLAVTLMALLKPGD-VIAVDALtYSGFKVLAETL--HLEML 199
Cdd:PRK06108 57 YTHNLGIPELREALARYVSRLhGVATPPERIAVTSSGVQALMLAAQALVGPGDeVVAVTPL-WPNLVAAPKILgaRVVCV 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 200 AIPLTASGPDLDHLHSLCRKHPVRAVYSMPTVHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFL----AEHAPPPL 275
Cdd:PRK06108 136 PLDFGGGGWTLDLDRLLAAITPRTRALFINSPNNPTGWTASRDDLRAILAHCRRHGLWIVADEVYERLyyapGGRAPSFL 215
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 817117913 276 ATLAPE-RTVYVGGFSKSVA-TGLRVGFVSAPAAWVKALERSIMATTWNVPGVMSAIAVAWLDDG--TVAQLEAQKRQ 349
Cdd:PRK06108 216 DIAEPDdRIIFVNSFSKNWAmTGWRLGWLVAPPALGQVLEKLIEYNTSCVAQFVQRAAVAALDEGedFVAELVARLRR 293
|
|
| YhcF |
COG1725 |
DNA-binding transcriptional regulator YhcF, GntR family [Transcription]; |
6-70 |
3.71e-16 |
|
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
Pssm-ID: 441331 [Multi-domain] Cd Length: 114 Bit Score: 74.06 E-value: 3.71e-16
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 817117913 6 YKNLVDTFAEDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFVRE 70
Cdd:COG1725 12 YEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAE 76
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
96-307 |
6.23e-16 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 79.08 E-value: 6.23e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 96 PSLPGQAELlRTALRQLALSGDlQALLRYQPHAGRQHERAAVARHLLSR-GLTVEADQVLLVSGAQHGLAVTLMALLKPG 174
Cdd:PRK06836 43 PSVPPPAAV-KEALRELAEEED-PGLHGYMPNAGYPEVREAIAESLNRRfGTPLTADHIVMTCGAAGALNVALKAILNPG 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 175 DVIAVDALTYSGFKVLAETLHLEMLAIPLTASG--PDLDHLHSLCRKHpVRAVYsMPTVHNPLGWVMSLEQREHLVAIAR 252
Cdd:PRK06836 121 DEVIVFAPYFVEYRFYVDNHGGKLVVVPTDTDTfqPDLDALEAAITPK-TKAVI-INSPNNPTGVVYSEETLKALAALLE 198
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 817117913 253 Q------HNLMIIEDAAYAFLA---EHAPPPLAtlAPERTVYVGGFSKSVA-TGLRVGFVSAPAA 307
Cdd:PRK06836 199 EkskeygRPIYLISDEPYREIVydgAEVPYIFK--YYDNSIVVYSFSKSLSlPGERIGYIAVNPE 261
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
124-310 |
2.70e-15 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 77.23 E-value: 2.70e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVARHLLS-RGLTVEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAIP 202
Cdd:PRK08361 66 YTPNAGIPELREAIAEYYKKfYGVDVDVDNVIVTAGAYEATYLAFESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 203 LTASG---PDLDHLHSLCRKHPVRAVYSMPtvHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYA-FLAEHAPP-PLAT 277
Cdd:PRK08361 146 LREENefqPDPDELLELITKRTRMIVINYP--NNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEhFLYEGAKHyPMIK 223
|
170 180 190
....*....|....*....|....*....|....
gi 817117913 278 LAPERTVYVGGFSKSVA-TGLRVGFVSAPAAWVK 310
Cdd:PRK08361 224 YAPDNTILANSFSKTFAmTGWRLGFVIAPEQVIK 257
|
|
| avtA |
PRK09440 |
valine--pyruvate transaminase; Provisional |
85-343 |
6.33e-15 |
|
valine--pyruvate transaminase; Provisional
Pssm-ID: 236517 Cd Length: 416 Bit Score: 76.05 E-value: 6.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 85 APGMLDLNFNYP-SLPGQAELLRTALRQLALSGDL-QALLRYQPHAGRQHERAAVARhLLSR--GLTVEADQVLLVSGAQ 160
Cdd:PRK09440 29 TPGAIMLGGGNPaHIPEMEDYFRDLLADLLASGKLtEALGNYDGPQGKDELIEALAA-LLNEryGWNISPQNIALTNGSQ 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 161 HG--LAVTLMALLKPGDV-------IAVDALTYSGfkvlaETLHLEMLA-----IPLTASG-----PDLDHLH------S 215
Cdd:PRK09440 108 SAffYLFNLFAGRRADGSlkkilfpLAPEYIGYAD-----AGLEEDLFVsyrpnIELLPEGqfkyhVDFEHLHidedtgA 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 216 LCrkhpvravYSMPTvhNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAF-----LAEHAPPPLAtlapERTVYVGGFS 290
Cdd:PRK09440 183 IC--------VSRPT--NPTGNVLTDEELEKLDALARQHNIPLLIDNAYGPpfpgiIFSEATPLWN----PNIILCMSLS 248
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 817117913 291 KSVATGLRVGFVSAPAAWVKALER--SIMATTwnVPGVMSAIAVAWLDDGTVAQL 343
Cdd:PRK09440 249 KLGLPGVRCGIVIADEEIIEALSNmnGIISLA--PGRLGPAIAAEMIESGDLLRL 301
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
124-302 |
2.06e-14 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 74.68 E-value: 2.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVARHLlSRGL--TVEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAI 201
Cdd:TIGR01265 69 YAPSVGALAAREAVAEYL-SSDLpgKLTADDVVLTSGCSQAIEICIEALANPGANILVPRPGFPLYDTRAAFSGLEVRLY 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 202 PLTASGP---DLDHLHSLCRKHPVRAVYSMPTvhNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLAEHAPP--PLA 276
Cdd:TIGR01265 148 DLLPEKDweiDLDGLESLADEKTVAIVVINPS--NPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAPfiPMA 225
|
170 180
....*....|....*....|....*...
gi 817117913 277 TLAPERTVYV-GGFSKS-VATGLRVGFV 302
Cdd:TIGR01265 226 SFASIVPVLSlGGISKRwVVPGWRLGWI 253
|
|
| MngR |
COG2188 |
DNA-binding transcriptional regulator, GntR family [Transcription]; |
1-70 |
5.42e-14 |
|
DNA-binding transcriptional regulator, GntR family [Transcription];
Pssm-ID: 441791 [Multi-domain] Cd Length: 238 Bit Score: 71.05 E-value: 5.42e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 1 MPRARYKNLVDTFAEDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFVRE 70
Cdd:COG2188 2 SPVPLYLQIADALRERIESGELPPGDRLPSERELAEEFGVSRMTVRKALDELVEEGLLERRQGRGTFVAE 71
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
119-306 |
2.33e-13 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 71.30 E-value: 2.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 119 QALLRYQPHAGRQHERAAVARHLLSR-GLTVEADQVLLVS-GAQHGLAVTLMALLKPGD-VIAVDA--LTYSGFKVLAET 193
Cdd:PRK07682 48 QGYTSYTANAGLLELRQEIAKYLKKRfAVSYDPNDEIIVTvGASQALDVAMRAIINPGDeVLIVEPsfVSYAPLVTLAGG 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 194 LhlemlAIPLTASGPDldhlHSLCRKHPVRAVYSMPTV-------HNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAF 266
Cdd:PRK07682 128 V-----PVPVATTLEN----EFKVQPAQIEAAITAKTKaillcspNNPTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAE 198
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 817117913 267 LA-EHAPPPLATLA--PERTVYVGGFSKSVA-TGLRVGFVSAPA 306
Cdd:PRK07682 199 LTyDEAYTSFASIKgmRERTILISGFSKGFAmTGWRLGFIAAPV 242
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
88-302 |
6.39e-13 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 69.81 E-value: 6.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 88 MLDLNFNYPSLPGQ---AELLRTALRQLALSGDLQAllrYQPHAGRQHERAAVARHLLSRGLTVEADQVLLVSGAQHGLA 164
Cdd:TIGR01264 33 MIKLSIGDPTVFGNlptDPEVMQAMKDSLDSGKYNG---YAPTVGALSAREAIASYYHNPDGPIEADDVVLCSGCSHAIE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 165 VTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAIPLTASGP---DLDHLHSLCRKHPVRAVYSMPTvhNPLGWVMSL 241
Cdd:TIGR01264 110 MCIAALANAGQNILVPRPGFPLYETLAESMGIEVKLYNLLPDKSweiDLKQLESLIDEKTAALIVNNPS--NPCGSVFSR 187
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 817117913 242 EQREHLVAIARQHNLMIIEDAAYAFL----AEHAppPLATLAPERTVYV-GGFSKS-VATGLRVGFV 302
Cdd:TIGR01264 188 QHLEEILAVAERQCLPIIADEIYGDMvfsgATFE--PLASLSSTVPILScGGLAKRwLVPGWRLGWI 252
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
135-305 |
1.24e-12 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 69.12 E-value: 1.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 135 AAVARHLLSRGLTVEAD-QVLLVSGAQHGLAVTLMALLKPGDVIAVDA---------LTYSGFKVLAETLHLEMLAIPLt 204
Cdd:PLN00175 99 AIAERFKKDTGLVVDPEkEVTVTSGCTEAIAATILGLINPGDEVILFApfydsyeatLSMAGAKIKTVTLRPPDFAVPE- 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 205 asgpdlDHLHSLCRKHpVRAVYsMPTVHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAY---AFLAEHAppPLATLAP- 280
Cdd:PLN00175 178 ------DELKAAFTSK-TRAIL-INTPHNPTGKMFTREELELIASLCKENDVLAFTDEVYdklAFEGDHI--SMASLPGm 247
|
170 180
....*....|....*....|....*..
gi 817117913 281 -ERTVYVGGFSKSVA-TGLRVGFVSAP 305
Cdd:PLN00175 248 yERTVTMNSLGKTFSlTGWKIGWAIAP 274
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
124-302 |
3.21e-12 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 67.91 E-value: 3.21e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVA-RHLLSRGLTVEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTY---SGFKVLAETLHLEML 199
Cdd:PRK08363 66 YGPSEGLPELREAIVkREKRKNGVDITPDDVRVTAAVTEALQLIFGALLDPGDEILIPGPSYppyTGLVKFYGGVPVEYR 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 200 AIPLTASGPDLDHLHSLCRKHPVRAVYSMPtvHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFL---AEHAPPplA 276
Cdd:PRK08363 146 TIEEEGWQPDIDDIRKKITEKTKAIAVINP--NNPTGALYEKKTLKEILDIAGEHDLPVISDEIYDLMtyeGKHVSP--G 221
|
170 180
....*....|....*....|....*...
gi 817117913 277 TLAPERTVYV-GGFSKS-VATGLRVGFV 302
Cdd:PRK08363 222 SLTKDVPVIVmNGLSKVyFATGWRLGYI 249
|
|
| HTH_GNTR |
smart00345 |
helix_turn_helix gluconate operon transcriptional repressor; |
15-68 |
6.74e-12 |
|
helix_turn_helix gluconate operon transcriptional repressor;
Pssm-ID: 197669 [Multi-domain] Cd Length: 60 Bit Score: 60.28 E-value: 6.74e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 817117913 15 EDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFV 68
Cdd:smart00345 7 EDIVSGELRPGDKLPSERELAAQLGVSRTTVREALSRLEAEGLVQRRPGSGTFV 60
|
|
| PRK07366 |
PRK07366 |
LL-diaminopimelate aminotransferase; |
124-350 |
8.20e-12 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 180947 Cd Length: 388 Bit Score: 66.63 E-value: 8.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVARHLLSR-GLTVEAD-QVLLVSGAQHGLAVTLMALLKPGDVIAvdaLTYSGFKVLAETLHL---EM 198
Cdd:PRK07366 64 YLLFHGTLDFREAAAQWYEQRfGLAVDPEtEVLPLIGSQEGTAHLPLAVLNPGDFAL---LLDPGYPSHAGGVYLaggQI 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 199 LAIPLTASG---PDLDHLHSLCRKHPVRAVYSMPtvHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYA--FLAEHAPP 273
Cdd:PRK07366 141 YPMPLRAENdflPVFADIPTEVLAQARLMVLSYP--HNPTTAIAPLSFFQEAVAFCQQHDLVLVHDFPYVdlVFDGEVEP 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 274 PLATLA-PERTVYVGGF--SKSVAT-GLRVGFVSAPAAWVKALERSIMATTWN-VPGVMS-AIAVAWLDDGTVAQLEA-- 345
Cdd:PRK07366 219 PSILQAdPEKSVSIEFFtlSKSYNMgGFRIGFAIGNAQLIQALRQVKAVVDFNqYRGILNgAIAALTGPQATVQQTVQif 298
|
....*
gi 817117913 346 QKRQD 350
Cdd:PRK07366 299 RQRRD 303
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
86-306 |
5.62e-11 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 64.00 E-value: 5.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 86 PGMLDLNFNYPSLPGQAELlRTALRQLALSGDLQAllrYQPHAGRQHERAAVARHLlsrglTVEADQVLLVSGAQHGLAV 165
Cdd:PRK06225 28 KEMIWMGQNTNHLGPHEEV-REAMIRCIEEGEYCK---YPPPEGFPELRELILKDL-----GLDDDEALITAGATESLYL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 166 TLMALLKPGD-VIAVDAlTYSGFKVLAETLHLEMLAIPLTASG------PDLdhlhslcrkhpVRAVYSMPTV------- 231
Cdd:PRK06225 99 VMRAFLSPGDnAVTPDP-GYLIIDNFASRFGAEVIEVPIYSEEcnykltPEL-----------VKENMDENTRliylidp 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 817117913 232 HNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYA-FLAEHapPPLATLAPERTVYVGGFSKSVA-TGLRVG-FVSAPA 306
Cdd:PRK06225 167 LNPLGSSYTEEEIKEFAEIARDNDAFLLHDCTYRdFAREH--TLAAEYAPEHTVTSYSFSKIFGmAGLRIGaVVATPD 242
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
147-312 |
1.21e-10 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 62.65 E-value: 1.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 147 TVEADQVLLVSGAQHGLAVTLMALLKPGD-VIAVdALTYSGFKVLAETLHLEMLAIPLTASG---PDLDHLHSLCRkhPV 222
Cdd:PRK07324 77 NVKPENILQTNGATGANFLVLYALVEPGDhVISV-YPTYQQLYDIPESLGAEVDYWQLKEENgwlPDLDELRRLVR--PN 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 223 RAVYSMPTVHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAY-AFLAEHAPPPLATLApERTVYVGGFSK--SVAtGLRV 299
Cdd:PRK07324 154 TKLICINNANNPTGALMDRAYLEEIVEIARSVDAYVLSDEVYrPLDEDGSTPSIADLY-EKGISTNSMSKtySLP-GIRV 231
|
170
....*....|...
gi 817117913 300 GFVSAPAAWVKAL 312
Cdd:PRK07324 232 GWIAANEEVIDIL 244
|
|
| GntR |
pfam00392 |
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ... |
6-68 |
5.01e-10 |
|
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.
Pssm-ID: 306822 [Multi-domain] Cd Length: 64 Bit Score: 55.31 E-value: 5.01e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 817117913 6 YKNLVDTFAEDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFV 68
Cdd:pfam00392 2 YEQVYARLREDILSGRLRPGDKLPSERELAAEFGVSRTTVREALRRLEAEGLVERRQGRGTFV 64
|
|
| PRK09148 |
PRK09148 |
LL-diaminopimelate aminotransferase; |
152-314 |
1.58e-09 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181674 [Multi-domain] Cd Length: 405 Bit Score: 59.31 E-value: 1.58e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 152 QVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYS----GFKVLAETLHlemlAIPLTasgPDLDHLHSLCR--KH----P 221
Cdd:PRK09148 94 QVVATLGSKEGFANMAQAITAPGDVILCPNPSYPihafGFIMAGGVIR----SVPAE---PDEEFFPALERavRHsipkP 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 222 VRAVYSMPTvhNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLA-EHAPPPLATLAP---ERTVYVGGFSKSVA-TG 296
Cdd:PRK09148 167 IALIVNYPS--NPTAYVADLDFYKDVVAFAKKHDIIILSDLAYSEIYfDGNPPPSVLQVPgakDVTVEFTSMSKTFSmAG 244
|
170
....*....|....*...
gi 817117913 297 LRVGFVSAPAAWVKALER 314
Cdd:PRK09148 245 WRMGFAVGNERLIAALTR 262
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
95-350 |
2.64e-09 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 58.83 E-value: 2.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 95 YPSLPGQAELLRTALRQLaLSGDLQallrYQPHAGRQHERAAVARHLLS-RGLTVE-ADQVLLVSGAQHGLAVTLMALLK 172
Cdd:PRK08912 35 FPDDPGPEDVRRAAADAL-LDGSNQ----YPPMMGLPELRQAVAAHYARfQGLDLDpETEVMVTSGATEALAAALLALVE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 173 PGDVIavdaltysgfkVLAETLHLEMLAIPLTASG-PDLDHLH----SLCRKhPVRAVYS-------MPTVHNPLGWVMS 240
Cdd:PRK08912 110 PGDEV-----------VLFQPLYDAYLPLIRRAGGvPRLVRLEpphwRLPRA-ALAAAFSprtkavlLNNPLNPAGKVFP 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 241 LEQREHLVAIARQHNLMIIEDAAYAFL--AEHAPPPLATL--APERTVYVGGFSKSVA-TGLRVGFVSAPAAWVKALERS 315
Cdd:PRK08912 178 REELALLAEFCQRHDAVAICDEVWEHVvfDGRRHIPLMTLpgMRERTVKIGSAGKIFSlTGWKVGFVCAAPPLLRVLAKA 257
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 817117913 316 IMATTWNVPGVMSAiAVAW---LDDGTVAQLEA--QKRQD 350
Cdd:PRK08912 258 HQFLTFTTPPNLQA-AVAYglgKPDDYFEGMRAdlARSRD 296
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
88-312 |
3.81e-09 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 58.28 E-value: 3.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 88 MLDLNFNYPSLPgQAELLRtalrqlalsgdlQALLRY--QPHA------GRQHERAAVARHLLSR-GLTVEAD-QVLLVS 157
Cdd:PRK07681 34 MIDLSIGNPDMP-PADFVR------------EEMVHTanQKESygytlsGIQEFHEAVTEYYNNThNVILNADkEVLLLM 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 158 GAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAIPLTASG---PDLDHLHSLCRKHPVRAVYSMPTvhNP 234
Cdd:PRK07681 101 GSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKENdflPDLELIPEEIADKAKMMILNFPG--NP 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 235 LGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLAEHAPPPLATL----APERTVYVGGFSKSVA-TGLRVGFVSAPAAWV 309
Cdd:PRK07681 179 VPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLsvpgAKEVGVEINSLSKSYSlAGSRIGYMIGNEEIV 258
|
...
gi 817117913 310 KAL 312
Cdd:PRK07681 259 RAL 261
|
|
| PRK05166 |
PRK05166 |
histidinol-phosphate transaminase; |
107-349 |
4.02e-09 |
|
histidinol-phosphate transaminase;
Pssm-ID: 179950 Cd Length: 371 Bit Score: 58.22 E-value: 4.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 107 TALRQLAlsgDLQALLRYQPHAGRQHERAAVARHLlsrglTVEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSG 186
Cdd:PRK05166 53 AVRRAFA---DIAELLRLYPDPQGRALREAIAART-----GVPADRIILGNGSEDLIAVICRAVLRPGDRVVTLYPSFPL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 187 FKVLAETLHLEMLAIPLTAS-GPDLDHLHSLCRKHPVRAVYSMPTvhNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYA 265
Cdd:PRK05166 125 HEDYPTMMGARVERVTVTPDlGFDLDALCAAVARAPRMLMFSNPS--NPVGSWLTADQLARVLDATPPETLIVVDEAYAE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 266 FLAEHAPPPLATLAPERT---VYVGGFSKSVA-TGLRVGF-VSAPAAWVKALERsiMATTWNVPGVMSAIA-VAWLDDG- 338
Cdd:PRK05166 203 YAAGDDYPSALTLLKARGlpwIVLRTFSKAYGlAGLRVGYgLVSDPELVGLLDR--VRTPFNVNGAAQAAAlAALDDEEh 280
|
250
....*....|....*...
gi 817117913 339 -------TVAQLEAQKRQ 349
Cdd:PRK05166 281 lakgvalALAERERLKKE 298
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
124-431 |
6.76e-09 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 57.49 E-value: 6.76e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVAR-------HLLSRGLTVEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHL 196
Cdd:PTZ00433 71 YPPTVGSPEAREAVATywrnsfvHKESLKSTIKKDNVVLCSGVSHAILMALTALCDEGDNILVPAPGFPHYETVCKAYGI 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 197 EMLAIPLTASGP---DLDHLHSLCRKHPVRAVYSMPTvhNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLAEH--- 270
Cdd:PTZ00433 151 EMRFYNCRPEKDweaDLDEIRRLVDDRTKALIMTNPS--NPCGSNFSRKHVEDIIRLCEELRLPLISDEIYAGMVFNgat 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 271 --------APPPLatlapertVYVGGFSKS-VATGLRVGFV------SAPAAWVKALERSIMATTWNVPGVMSAIAVAWL 335
Cdd:PTZ00433 229 ftsvadfdTTVPR--------VILGGTAKNlVVPGWRLGWLllvdphGNGGDFLDGMKRLGMLVCGPCSVVQAALGEALL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 336 D------DGTVAQLEAqkrqdaraRQALAAQVLK---GLTYISHPSSYFLWLPLAEEARADQIA------MTLQRENIAV 400
Cdd:PTZ00433 301 NtpqehlEQIVAKLEE--------GAMVLYNHIGeciGLSPTMPRGSMFLMSRLDLEKFRDIKSdvefyeKLLEEENVQV 372
|
330 340 350
....*....|....*....|....*....|.
gi 817117913 401 STAEPFavsaHVPHALRLALgSVDMTALREA 431
Cdd:PTZ00433 373 LPGEIF----HMPGFTRLTI-SRPVEVLREA 398
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
88-334 |
9.17e-09 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 56.89 E-value: 9.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 88 MLDLNFNYPSLPGQAELLRtALRQLALSgdlQALLRYQPHAGRQHERAAVARHLLSR-GLTVEADQVLLVSGAQHGLAVT 166
Cdd:PRK07550 31 LIDLSQAVPGYPPPPELLR-ALAEAAAD---PAAHLYGPVEGLPELREAYAAHYSRLyGAAISPEQVHITSGCNQAFWAA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 167 LMALLKPGDVIAVDALTYSGFKvlaetLHLEMLAI------PLTASG--PDLDHLHSLCRKHpVRAVySMPTVHNPLGWV 238
Cdd:PRK07550 107 MVTLAGAGDEVILPLPWYFNHK-----MWLDMLGIrpvylpCDEGPGllPDPAAAEALITPR-TRAI-ALVTPNNPTGVV 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 239 MSLEQREHLVAIARQHNLMIIEDAAYAFLAEHAPPPLATLA----PERTVYVGGFSKSVA-TGLRVGFVSAPAAWVKALE 313
Cdd:PRK07550 180 YPPELLHELYDLARRHGIALILDETYRDFDSGGGAPHDLFAdpdwDDTLVHLYSFSKSYAlTGHRVGAVVASPARIAEIE 259
|
250 260
....*....|....*....|.
gi 817117913 314 RsIMATTWNVPGVMSAIAVAW 334
Cdd:PRK07550 260 K-FMDTVAICAPRIGQIAVAW 279
|
|
| C_P_lyase_phnF |
TIGR02325 |
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for ... |
4-68 |
1.45e-08 |
|
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for this family are predicted helix-turn-helix transcriptional regulatory proteins of the broader gntR and are found associated with genes for the import and degradation of phosphonates and/or related compounds (e.g. phosphonites) with a direct C-P bond. [Transport and binding proteins, Anions, Regulatory functions, DNA interactions]
Pssm-ID: 131378 [Multi-domain] Cd Length: 238 Bit Score: 55.17 E-value: 1.45e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 817117913 4 ARYKNLVDTFAEDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFV 68
Cdd:TIGR02325 8 ALWRQIADKIEQEIAAGHLRAGDYLPAEMQLAERFGVNRHTVRRAIAALVERGLLRAEQGRGTFV 72
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
124-306 |
1.50e-08 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 56.27 E-value: 1.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVARHLLSR-GLTVEAD-QVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLaetlhlemlaI 201
Cdd:PRK07683 61 YTHNAGLLELRKAACNFVKDKyDLHYSPEsEIIVTIGASEAIDIAFRTILEPGTEVILPAPIYPGYEPI----------I 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 202 PLTASGPdldhLHSLCRKHPVRAVYS--------------MPTVHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFL 267
Cdd:PRK07683 131 RLCGAKP----VFIDTRSTGFRLTAEalenaitektrcvvLPYPSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSEL 206
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 817117913 268 AEHAPP-PLATLA--PERTVYVGGFSKSVA-TGLRVGFVSAPA 306
Cdd:PRK07683 207 VYEQPHtSIAHFPemREKTIVINGLSKSHSmTGWRIGFLFAPS 249
|
|
| Asp_aminotransf |
pfam12897 |
Aspartate amino-transferase; These proteins catalyze the reversible transfer of an amino group ... |
190-320 |
4.81e-08 |
|
Aspartate amino-transferase; These proteins catalyze the reversible transfer of an amino group from the amino acid substrate to an acceptor alpha-keto acid. They require pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze this reaction. Trans-amination reactions are of central importance in amino acid metabolism and in links to carbohydrate and fat metabolism. This class of amino-transferases acts as dimers in a head-to-tail configuration. It has been demonstrated that these proteins are aspartate amino-transferases from Bacteria (Jansen, R.S. et al. Nat Commun 11, 1960 (2020)).
Pssm-ID: 403948 Cd Length: 419 Bit Score: 54.87 E-value: 4.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 190 LAETLHLEMLAIPLTASGPDLDHLHSLCRKHP-VRAVYSMPTVHNPLGWVMSLEQREHLVAI-ARQHNLMIIEDAAYA-- 265
Cdd:pfam12897 139 ILETLGIEMITVDLQDDGPDMDAVERLVAKDPsIKGIWFVPKYSNPTGETISEEVARRLAGMkTAAPDFRIFWDNAYAvh 218
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 817117913 266 --FLAEHAPPPLATLA-----PERTVYVGGFSKSVATGLRVGFVSAPAAWVKALERSIMATT 320
Cdd:pfam12897 219 hlVGEGDRDPNIVGLArdaghPNRPFVFASTSKITFAGAGVGFVASSEDNIAWLGKYLGAQS 280
|
|
| FadR |
COG2186 |
DNA-binding transcriptional regulator, FadR family [Transcription]; |
2-72 |
5.93e-08 |
|
DNA-binding transcriptional regulator, FadR family [Transcription];
Pssm-ID: 441789 [Multi-domain] Cd Length: 232 Bit Score: 53.40 E-value: 5.93e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 817117913 2 PRARYKNLVDTFAEDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFVREIS 72
Cdd:COG2186 5 RRSLAEQVAEQLRELILSGELKPGDRLPSERELAEQLGVSRTTVREALRALEALGLVEVRQGGGTFVREPS 75
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
158-311 |
9.11e-08 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 53.89 E-value: 9.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 158 GAQHGLAVTLMALLKPGDVIAvdaLTYSGFKVLA---ETLHLEMLAIPLTASG---PDLDHLHSLCRKHPVRAVYSMPtv 231
Cdd:PRK06290 114 GSKPALAMLPSCFINPGDVTL---MTVPGYPVTGthtKYYGGEVYNLPLLEENnflPDLDSIPKDIKEKAKLLYLNYP-- 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 232 HNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLAeHAPPPLATL----APERTVYVGGFSKSV-ATGLRVGFVSAPA 306
Cdd:PRK06290 189 NNPTGAVATKEFYEEVVDFAKENNIIVVQDAAYAALT-FDGKPLSFLsvpgAKEVGVEIHSLSKAYnMTGWRLAFVVGNE 267
|
....*
gi 817117913 307 AWVKA 311
Cdd:PRK06290 268 LIVKA 272
|
|
| PRK05839 |
PRK05839 |
succinyldiaminopimelate transaminase; |
233-400 |
1.38e-07 |
|
succinyldiaminopimelate transaminase;
Pssm-ID: 180281 Cd Length: 374 Bit Score: 53.15 E-value: 1.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 233 NPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLAEHAPPPlATLapERTVYVGGFS------------KSVATGLRVG 300
Cdd:PRK05839 166 NPTGRTLSLEELIEWVKLALKHDFILINDECYSEIYENTPPP-SLL--EASILVGNESfknvlvinsiskRSSAPGLRSG 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 301 FVSAPAAWVKA--LERSIMATTWNVPgVMSAIAVAWLDDGTVAQLeaqkRQDARARQALAAQVLKGLTYishPSSYFLWL 378
Cdd:PRK05839 243 FIAGDASILKKykAYRTYLGCASPLP-LQKAAAVAWLDDEHAEFF----RNIYAKNLKLAREILGITIP---PATFYVWL 314
|
170 180
....*....|....*....|....*
gi 817117913 379 PLaeearADQIAMT---LQRENIAV 400
Cdd:PRK05839 315 PV-----DNDEEFTkklYQNEGIKV 334
|
|
| PRK08175 |
PRK08175 |
aminotransferase; Validated |
123-386 |
1.45e-07 |
|
aminotransferase; Validated
Pssm-ID: 181268 [Multi-domain] Cd Length: 395 Bit Score: 53.18 E-value: 1.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 123 RYQPHAGRQHERAAVARHLLSRgLTVEAD---QVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYS----GFkVLAETlh 195
Cdd:PRK08175 62 GYSTSRGIPRLRRAISRWYQDR-YDVDIDpesEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPihiyGA-VIAGA-- 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 196 lEMLAIPLTasgPDLDHLHSLCRKhpVRAVYSMPTV------HNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYA---F 266
Cdd:PRK08175 138 -QVRSVPLV---EGVDFFNELERA--IRESYPKPKMmilgfpSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYAdivY 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 267 LAEHAPPPLaTLAPERTVYVGGFSKSVA---TGLRVGFVSAPAAWVKALER--SIMATTWNVPGVMSAIAVAWLDDGTVA 341
Cdd:PRK08175 212 DGWKAPSIM-QVPGAKDVAVEFFTLSKSynmAGWRIGFMVGNPELVSALARikSYHDYGTFTPLQVAAIAALEGDQQCVR 290
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 817117913 342 QLEA--QKRQDararqalaaqVL-KGLTYISHP-----SSYFLWLPLAEEARA 386
Cdd:PRK08175 291 DIAEqyKRRRD----------VLvKGLHEAGWMvempkASMYVWAKIPEPYAA 333
|
|
| PRK09764 |
PRK09764 |
GntR family transcriptional regulator; |
5-70 |
2.00e-07 |
|
GntR family transcriptional regulator;
Pssm-ID: 182065 [Multi-domain] Cd Length: 240 Bit Score: 51.75 E-value: 2.00e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 817117913 5 RYKNLVDTFAEDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFVRE 70
Cdd:PRK09764 6 LYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYVKE 71
|
|
| PRK09276 |
PRK09276 |
LL-diaminopimelate aminotransferase; Provisional |
123-382 |
2.33e-07 |
|
LL-diaminopimelate aminotransferase; Provisional
Pssm-ID: 181749 Cd Length: 385 Bit Score: 52.61 E-value: 2.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 123 RYQPHAGRQHERAAVARHLLSRgLTVEAD---QVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKV---LAETlhl 196
Cdd:PRK09276 64 QYPSYEGMLEFRKAVADWYKRR-FGVELDpetEVISLIGSKEGIAHIPLAFVNPGDVVLVPDPGYPVYKIgtiFAGG--- 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 197 EMLAIPLTASG---PDLDHL-HSLCRKHPVRAV-YsmPtvHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAY---AFLA 268
Cdd:PRK09276 140 EPYFMPLKEENgflPDLDAIpEDVAKKAKLMFInY--P--NNPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYseiAYDG 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 269 EHAPPPLATL-APERTVYVGGFSKSV-ATGLRVGFVSAPAAWVKALERSIMattwNV-PGVMSAI---AVAWL--DDGTV 340
Cdd:PRK09276 216 YKPPSFLEVPgAKDVGIEFHSLSKTYnMTGWRIGFAVGNADLIAGLGKVKS----NVdSGVFQAIqeaGIAALngPQEVV 291
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 817117913 341 AQLEA--QKRQDararqalaaQVLKGLTYISHP-----SSYFLWLPLAE 382
Cdd:PRK09276 292 EELRKiyQERRD---------ILVEGLRKLGLEveppkATFYVWAPVPK 331
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
80-307 |
2.52e-07 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 52.48 E-value: 2.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 80 GQMNVAPGMLDLNFNYPSLPGQAELLRTALRQLAlSGDLQallrYQPHAGRQHERAAVARHLLS-RGLTVEAD-QVLLVS 157
Cdd:PRK12414 23 GQLAAQHDALNLSQGAPNFAPDPALVEGVARAMR-DGHNQ----YAPMAGIAALREALAEKTERlYGARYDPAsEVTVIA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 158 GAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAIPLTASGPDLDHLHSLCRKHPVRAVYSMPTVHNPLGW 237
Cdd:PRK12414 98 SASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPEDFRVNWDEVAAAITPRTRMIIVNTPHNPSAT 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 238 VMSLEQREHLVAIARQHNLMIIEDAAYAF----------LAEHapPPLAtlapERTVYVGGFSKSV-ATGLRVGFVSAPA 306
Cdd:PRK12414 178 VFSAADLARLAQLTRNTDIVILSDEVYEHvvfdgarhhsMARH--RELA----ERSVIVSSFGKSYhVTGWRVGYCLAPA 251
|
.
gi 817117913 307 A 307
Cdd:PRK12414 252 E 252
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
115-337 |
3.36e-07 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 52.07 E-value: 3.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 115 SGDLQAllrYQPHAGRQHERAAVARHLLS-RGLTVEA-DQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAE 192
Cdd:PRK06207 68 RGGVQA---YTEYRGDADIRELLAARLAAfTGAPVDAaDELIITPGTQGALFLAVAATVARGDKVAIVQPDYFANRKLVE 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 193 TLHLEMLAIPL------TASGPDLDHLHSLCRKHPVRAVYSMPtvHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAF 266
Cdd:PRK06207 145 FFEGEMVPVQLdylsadKRAGLDLDQLEEAFKAGVRVFLFSNP--NNPAGVVYSAEEIAQIAALARRYGATVIVDQLYSR 222
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 817117913 267 L--AEHAPPPLATLA--PERTVYVGGFSKSVA-TGLRVGFVSAPAAWVKALERSIMATTWNVPGVMSAIAVAWLDD 337
Cdd:PRK06207 223 LlyDGTSYTHLRALPidPENVITIMGPSKTESlSGYRLGVAFGSPAIIDRMEKLQAIVSLRAAGYSQAVLRTWFSE 298
|
|
| PRK09265 |
PRK09265 |
aminotransferase AlaT; Validated |
134-333 |
3.99e-07 |
|
aminotransferase AlaT; Validated
Pssm-ID: 181738 Cd Length: 404 Bit Score: 51.74 E-value: 3.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 134 RAAVARHLLSRGLT-VEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYsgfkvlaetlhlemlaiPL-TA----SG 207
Cdd:PRK09265 78 RKAIMQYYQQKGIPdVDVDDIYIGNGVSELIVMAMQALLNNGDEVLVPAPDY-----------------PLwTAavslSG 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 208 ---------------PDLDHLHSLCRKHpVRA-VYSMPtvHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFL---- 267
Cdd:PRK09265 141 gkpvhylcdeeagwfPDLDDIRSKITPR-TKAiVIINP--NNPTGAVYSKELLEEIVEIARQHNLIIFADEIYDKIlydg 217
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 817117913 268 AEHAppPLATLAPER-TVYVGGFSKSV-ATGLRVG--FVSAPAAWVKALERSI-----MATTWNVPGvMSAIAVA 333
Cdd:PRK09265 218 AVHI--SIASLAPDLlCVTFNGLSKAYrVAGFRVGwmVLSGPKKHAKGYIEGLdmlasMRLCANVPA-QHAIQTA 289
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
124-304 |
4.44e-07 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 51.69 E-value: 4.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVARHLlSRGL--TVEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLA-----ETLHL 196
Cdd:PLN00145 90 YSTCVGLLPARRAIAEYL-SRDLpyELSTDDIYLTAGCAQAIEIIMSVLAQPGANILLPRPGYPLYEARAvfsglEVRHF 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 197 EMLaiPLTASGPDLDHLHSLCRKHPVRAVYSMPTvhNPLGWVMSleqREHLVAIA---RQHNLMIIEDAAYAFLAEHAPP 273
Cdd:PLN00145 169 DLL--PERGWEVDLEGVEALADENTVAMVIINPN--NPCGSVYS---YEHLAKIAetaRKLGILVIADEVYDHLTFGSKP 241
|
170 180 190
....*....|....*....|....*....|....*..
gi 817117913 274 --PL---ATLAPERTvyVGGFSKS-VATGLRVGFVSA 304
Cdd:PLN00145 242 fvPMgvfGEVAPVLT--LGSISKRwVVPGWRLGWIAT 276
|
|
| PLN02656 |
PLN02656 |
tyrosine transaminase |
124-303 |
6.55e-07 |
|
tyrosine transaminase
Pssm-ID: 178262 [Multi-domain] Cd Length: 409 Bit Score: 51.46 E-value: 6.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVARHLlSRGL--TVEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAI 201
Cdd:PLN02656 69 YAPTVGLPQARRAIAEYL-SRDLpyKLSLDDVFITSGCTQAIDVALSMLARPGANILLPRPGFPIYELCAAFRHLEVRYV 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 202 PLTASG---PDLDHLHSLCRKHPVRAVYSMPtvHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLAEHAPP--PL- 275
Cdd:PLN02656 148 DLLPEKgweVDLDAVEALADQNTVALVIINP--GNPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAFGSNPfvPMg 225
|
170 180 190
....*....|....*....|....*....|..
gi 817117913 276 --ATLAPERTvyVGGFSKS-VATGLRVG-FVS 303
Cdd:PLN02656 226 vfGSIVPVLT--LGSLSKRwIVPGWRLGwFVT 255
|
|
| PRK08068 |
PRK08068 |
transaminase; Reviewed |
123-406 |
1.32e-06 |
|
transaminase; Reviewed
Pssm-ID: 181219 Cd Length: 389 Bit Score: 50.31 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 123 RYQPHAGRQHERAAVARHLLSR-GLTVEAD-QVLLVSGAQHGLAVTLMALLKPGDVIAVDALTY----SGFkVLAEtlhL 196
Cdd:PRK08068 65 KYSPFRGYPFLKEAAADFYKREyGVTLDPEtEVAILFGGKAGLVELPQCLMNPGDTILVPDPGYpdylSGV-ALAR---A 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 197 EMLAIPLTASG---PDLDHLHSLCRKhpvRA-VYSMPTVHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLAEHAP 272
Cdd:PRK08068 141 QFETMPLIAENnflPDYTKIPEEVAE---KAkLMYLNYPNNPTGAVATKAFFEETVAFAKKHNIGVVHDFAYGAIGFDGQ 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 273 PPLATLAPERTVYVG----GFSKSV-ATGLRVGFVSAPAAWVKALER-------SIMattwnvPGVMSAIAVAWLDDGT- 339
Cdd:PRK08068 218 KPVSFLQTPGAKDVGielyTLSKTFnMAGWRVAFAVGNESVIEAINLlqdhlfvSLF------GAIQDAAIEALLSDQSc 291
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 340 VAQLEA--QKRQDARARQALAAqvlkGLTYISHPSSYFLWLPLAEEARADQIA-MTLQRENIAVSTAEPF 406
Cdd:PRK08068 292 VAELVAryESRRNAFISACREI----GWEVDAPKGSFFAWMPVPKGYTSEQFAdLLLEKAHVAVAPGNGF 357
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
124-307 |
1.58e-06 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 49.91 E-value: 1.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVARHLLSR-GLTVEAD-QVLLVSGAQHGLAVTLMALLKPGD-VIAVDAlTYSGFKVLAETLHLEMLA 200
Cdd:PRK09082 63 YPPMTGVAALREAIAAKTARLyGRQYDADsEITVTAGATEALFAAILALVRPGDeVIVFDP-SYDSYAPAIELAGGRAVR 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 201 IPLTASG--PDLDHLHSLCRKHpVRAVYsMPTVHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFL----AEHAP-- 272
Cdd:PRK09082 142 VALQPPDfrVDWQRFAAAISPR-TRLII-LNTPHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVYEHIvfdgAGHASvl 219
|
170 180 190
....*....|....*....|....*....|....*...
gi 817117913 273 --PPLAtlapERTVYVGGFSKSV-ATGLRVGFVSAPAA 307
Cdd:PRK09082 220 rhPELR----ERAFVVSSFGKTYhVTGWKVGYCVAPAA 253
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
124-302 |
1.71e-06 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 50.01 E-value: 1.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVARHLlSRGL--TVEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLA- 200
Cdd:PLN00143 70 YAPTGGILPARRAIADYL-SNDLpyQLSPDDVYLTLGCKHAAEIIIKVLARPEANILLPRPGFPDVETYAIFHHLEIRHf 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 201 --IPLTASGPDLDHLHSLCRKHPVRAVYSMPTvhNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLAEHAPP--PL- 275
Cdd:PLN00143 149 dlLPEKGWEVDLDAVEAIADENTIAMVIINPG--NPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVFGSKPfvPMg 226
|
170 180 190
....*....|....*....|....*....|
gi 817117913 276 --ATLAPerTVYVGGFSKS-VATGLRVGFV 302
Cdd:PLN00143 227 lfASIVP--VITLGSISKRwMIPGWGLGWL 254
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
123-314 |
6.08e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 48.13 E-value: 6.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 123 RYQPHAGRQHERAAVARHLLSR-GLTVEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAI 201
Cdd:PRK08960 64 RYTAARGLPALREAIAGFYAQRyGVDVDPERILVTPGGSGALLLASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLV 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 202 PLTASG---PDLDHLHSLCRKHPVRAVYSMPTvhNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLAEHAPPPLATL 278
Cdd:PRK08960 144 PVGPDSryqLTPALVERHWNADTVGALVASPA--NPTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYGVDAASVLE 221
|
170 180 190
....*....|....*....|....*....|....*..
gi 817117913 279 APERTVYVGGFSKSVA-TGLRVGFVSAPAAWVKALER 314
Cdd:PRK08960 222 VDDDAFVLNSFSKYFGmTGWRLGWLVAPPAAVPELEK 258
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
86-432 |
7.07e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 48.14 E-value: 7.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 86 PGMLDLN---FNYPSLPGQAELLRTALRQlalsgdlQALLRYQPHAGRQHERAAVARHLLS-RGLTVEADQVLLVS-GAQ 160
Cdd:PRK05957 27 PGTISLGqgvVSYPPPPEAIEALNNFLAN-------PENHKYQAVQGIPPLLEAITQKLQQdNGIELNNEQAIVVTaGSN 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 161 HGLAVTLMALLKPGDVIAVDALTY----------SGFKVLAET-----LHLEMLAIPLTASgpdldhlhslcrkhpVRAV 225
Cdd:PRK05957 100 MAFMNAILAITDPGDEIILNTPYYfnhemaitmaGCQPILVPTddnyqLQPEAIEQAITPK---------------TRAI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 226 YSMpTVHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLA----EHAPPplATLAPERTVYVGGFSKSVATGL---R 298
Cdd:PRK05957 165 VTI-SPNNPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTydgvKHFSP--GSIPGSGNHTISLYSLSKAYGFaswR 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 299 VGFVSAPAAWVKALERsIMATTWNVPGVMSA-IAVAWLDDGT------VAQLeAQKRQdararqalaaQVLKGLTYIS-- 369
Cdd:PRK05957 242 IGYMVIPIHLLEAIKK-IQDTILICPPVVSQyAALGALQVGKsycqqhLPEI-AQVRQ----------ILLKSLGQLQdr 309
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 370 ---HPSS---YFLwLPLAEEARADQIAMTLQRE-NIAVSTAEPFAVSAHVphALRLALGSVDMTALREAL 432
Cdd:PRK05957 310 ctlHPANgafYCF-LKVNTDLNDFELVKQLIREyRVAVIPGTTFGMKNGC--YLRIAYGALQKATAKEGI 376
|
|
| PRK11402 |
PRK11402 |
transcriptional regulator PhoB; |
6-69 |
8.47e-06 |
|
transcriptional regulator PhoB;
Pssm-ID: 183118 [Multi-domain] Cd Length: 241 Bit Score: 46.75 E-value: 8.47e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 817117913 6 YKNLVDTFAEDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFVR 69
Cdd:PRK11402 11 YATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIRWQGKGTFVQ 74
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
233-303 |
1.39e-05 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 47.42 E-value: 1.39e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 817117913 233 NPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFL----AEHAppPLATLAPER-TVYVGGFSKS--VAtGLRVGFVS 303
Cdd:PRK13355 292 NPTGALYPREVLQQIVDIAREHQLIIFSDEIYDRLvmdgLEHT--SIASLAPDLfCVTFSGLSKShmIA-GYRIGWMI 366
|
|
| PRK08636 |
PRK08636 |
LL-diaminopimelate aminotransferase; |
232-401 |
1.86e-05 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 236316 Cd Length: 403 Bit Score: 46.62 E-value: 1.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 232 HNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLA--EHAPPPLATLAPERTVYVGGF--SKSV-ATGLRVGFVSAPA 306
Cdd:PRK08636 185 HNPTTATVEKSFYERLVALAKKERFYIISDIAYADITfdGYKTPSILEVEGAKDVAVESYtlSKSYnMAGWRVGFVVGNK 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 307 AWVKALERsimATTWNVPGVMSAIAVAwlddGTVAQLEAQ-----------KRQDARARQALAAqvlkGLTYISHPSSYF 375
Cdd:PRK08636 265 KLVGALKK---IKSWLDYGMFTPIQVA----ATIALDGDQscveeiretyrKRRDVLIESFANA----GWELQKPRASMF 333
|
170 180 190
....*....|....*....|....*....|
gi 817117913 376 LWLPLAEEARA----DQIAMTLQRENIAVS 401
Cdd:PRK08636 334 VWAKIPEPARHlgslEFSKQLLTEAKVAVS 363
|
|
| PRK09147 |
PRK09147 |
succinyldiaminopimelate transaminase; Provisional |
233-400 |
6.62e-05 |
|
succinyldiaminopimelate transaminase; Provisional
Pssm-ID: 236393 Cd Length: 396 Bit Score: 44.87 E-value: 6.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 233 NPLGWVMSLEQREHLVAIARQHNLMIIEDAAYA--FLAEHAPPPLATLAP--------ERTVYVGGFSK-SVATGLRVGF 301
Cdd:PRK09147 177 NPTGAVLPLDDWKKLFALSDRYGFVIASDECYSeiYFDEAAPPLGLLEAAaelgrddfKRLVVFHSLSKrSNVPGLRSGF 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 302 VSAPAAWVKA--LER----SIMAttwnvPGVMSAIAVAWLDDGTVAQLEAQKRQDARARQALAAQVLKgltyISHP-SSY 374
Cdd:PRK09147 257 VAGDAALLKKflLYRtyhgCAMP-----PAVQAASIAAWNDEAHVRENRALYREKFDAVTPILAPVLD----VQLPdAGF 327
|
170 180
....*....|....*....|....*...
gi 817117913 375 FLWL--PLAEEARADQIamtLQRENIAV 400
Cdd:PRK09147 328 YLWAkvPGDDTEFARRL---YADYNVTV 352
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
148-296 |
7.67e-05 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 44.45 E-value: 7.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 148 VEADQVLLVSGAQHGLAVTLMAL-LKPGDVIAVDALTYS---------GFK-----VLAETLHLemlaipltasgpDLDH 212
Cdd:cd00616 31 LGVKYAVAVSSGTAALHLALRALgIGPGDEVIVPSFTFVatanailllGATpvfvdIDPDTYNI------------DPEL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 213 LHSLCRKHPvRAVysMPtVHnPLGWVMSLEQrehLVAIARQHNLMIIEDAAYAFLAEHAPPPLATLApertvYVGGFS-- 290
Cdd:cd00616 99 IEAAITPRT-KAI--IP-VH-LYGNPADMDA---IMAIAKRHGLPVIEDAAQALGATYKGRKVGTFG-----DAGAFSfh 165
|
....*...
gi 817117913 291 --KSVATG 296
Cdd:cd00616 166 ptKNLTTG 173
|
|
| PRK14999 |
PRK14999 |
histidine utilization repressor; Provisional |
2-79 |
8.26e-05 |
|
histidine utilization repressor; Provisional
Pssm-ID: 184961 [Multi-domain] Cd Length: 241 Bit Score: 43.77 E-value: 8.26e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 817117913 2 PRARYKNLVDTFAEDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFVREislPPGQGS 79
Cdd:PRK14999 10 PAPFYETVKQDICKKIAGGVWQPHDRIPSEAELVAQYGFSRMTINRALRELTDEGWLVRLQGVGTFVAE---PKGQSA 84
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
133-270 |
1.28e-04 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 43.90 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 133 ERAAVARHLLSRGLT---------------VEADQVLLVSGAQHGLAVTLMAL-LKPGD-VIAVD--------ALTYSGF 187
Cdd:COG0399 13 EIAAVVEVLRSGWLTlgpevkefeeefaayLGVKHAVAVSSGTAALHLALRALgIGPGDeVITPAftfvatanAILYVGA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 188 K-VLA----ETLHLemlaipltasgpDLDHLHSLCRKHPvRAVysMPtVHnPLGWVMSLEQrehLVAIARQHNLMIIEDA 262
Cdd:COG0399 93 TpVFVdidpDTYNI------------DPEALEAAITPRT-KAI--IP-VH-LYGQPADMDA---IMAIAKKHGLKVIEDA 152
|
....*...
gi 817117913 263 AYAFLAEH 270
Cdd:COG0399 153 AQALGATY 160
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
134-263 |
2.35e-04 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 43.20 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 134 RAAVARHLlsrGlTVEADQVLLVSGAQHG--LAVTLMALLKPGDVIAVDALTYSG----FKVLAETLHLEMLAIPLTASG 207
Cdd:COG0520 65 REKVARFI---G-AASPDEIIFTRGTTEAinLVAYGLGRLKPGDEILITEMEHHSnivpWQELAERTGAEVRVIPLDEDG 140
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 817117913 208 -PDLDHLHSLCRKhPVRAVySMPTVHNPLGWVMSLEQrehLVAIARQHNLMIIEDAA 263
Cdd:COG0520 141 eLDLEALEALLTP-RTKLV-AVTHVSNVTGTVNPVKE---IAALAHAHGALVLVDGA 192
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
135-268 |
5.28e-04 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 40.44 E-value: 5.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 135 AAVARHLLSRGLTVEADQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLAI----PLTASGPDL 210
Cdd:cd01494 2 LEELEEKLARLLQPGNDKAVFVPSGTGANEAALLALLGPGDEVIVDANGHGSRYWVAAELAGAKPVPvpvdDAGYGGLDV 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 817117913 211 DHLHSLCRKHPVRAVYSMPTVHNPLGWVMSLEqrehLVAIARQHNLMIIEDAAYAFLA 268
Cdd:cd01494 82 AILEELKAKPNVALIVITPNTTSGGVLVPLKE----IRKIAKEYGILLLVDAASAGGA 135
|
|
| PRK10421 |
PRK10421 |
DNA-binding transcriptional repressor LldR; Provisional |
9-86 |
2.13e-03 |
|
DNA-binding transcriptional repressor LldR; Provisional
Pssm-ID: 236690 [Multi-domain] Cd Length: 253 Bit Score: 39.75 E-value: 2.13e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 817117913 9 LVDTFAEDIRSGRLSPGERLPTHRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFVREislPPGQGSGQMNVAP 86
Cdd:PRK10421 7 VADRVRALIEEKNLEAGMKLPAERQLAMQLGVSRNSLREALAKLVSEGVLLSRRGGGTFIRW---RHETWSEQNIVQP 81
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
150-278 |
4.16e-03 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 39.15 E-value: 4.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 150 ADQVLLVSGAQHGL---AVTLMALLKPGDVIAVDALTYSGFKV----LAETLHLEMLAIPLTASG-PDLDHLHSLCRkHP 221
Cdd:pfam00266 61 NDEIIFTSGTTEAInlvALSLGRSLKPGDEIVITEMEHHANLVpwqeLAKRTGARVRVLPLDEDGlLDLDELEKLIT-PK 139
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 817117913 222 VRAVYSMPtVHNPLGWVMSLEqreHLVAIARQHNLMIIEDAAYAFLaeHAPPPLATL 278
Cdd:pfam00266 140 TKLVAITH-VSNVTGTIQPVP---EIGKLAHQYGALVLVDAAQAIG--HRPIDVQKL 190
|
|
| PRK06855 |
PRK06855 |
pyridoxal phosphate-dependent aminotransferase; |
208-276 |
4.31e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180734 Cd Length: 433 Bit Score: 39.16 E-value: 4.31e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 817117913 208 PDLDHLHSLCRKHPVRAVYSMPTVHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLA--EHAPPPLA 276
Cdd:PRK06855 157 PDLDDLENKVKYNPSIAGILLINPDNPTGAVYPKEILREIVDIAREYDLFIICDEIYNNIVynGKKTVPLS 227
|
|
| PLN02187 |
PLN02187 |
rooty/superroot1 |
124-303 |
4.77e-03 |
|
rooty/superroot1
Pssm-ID: 215119 [Multi-domain] Cd Length: 462 Bit Score: 39.32 E-value: 4.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 124 YQPHAGRQHERAAVARHL---LSRGLTVEadQVLLVSGAQHGLAVTLMALLKPGDVIAVDALTYSGFKVLAETLHLEMLA 200
Cdd:PLN02187 104 YGPGAGILPARRAVADYMnrdLPHKLTPE--DIFLTAGCNQGIEIVFESLARPNANILLPRPGFPHYDARAAYSGLEVRK 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 817117913 201 IPLTASGP---DLDHLHSLCRKHPVRAVYSMPtvHNPLGWVMSLEQREHLVAIARQHNLMIIEDAAYAFLAEHAPP---- 273
Cdd:PLN02187 182 FDLLPEKEweiDLEGIEAIADENTVAMVVINP--NNPCGNVYSHDHLKKVAETARKLGIMVISDEVYDRTIFGDNPfvsm 259
|
170 180 190
....*....|....*....|....*....|..
gi 817117913 274 -PLATLAPERTvyVGGFSKS-VATGLRVGFVS 303
Cdd:PLN02187 260 gKFASIVPVLT--LAGISKGwVVPGWKIGWIA 289
|
|
| GntR |
COG1802 |
DNA-binding transcriptional regulator, GntR family [Transcription]; |
11-73 |
5.08e-03 |
|
DNA-binding transcriptional regulator, GntR family [Transcription];
Pssm-ID: 441407 [Multi-domain] Cd Length: 222 Bit Score: 38.36 E-value: 5.08e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 817117913 11 DTFAEDIRSGRLSPGERLPThRQLAARHGLALVTASRVYSELAAMGLVSGETGRGTFVREISL 73
Cdd:COG1802 18 EALREAILSGELPPGERLSE-AELAERLGVSRTPVREALRRLEAEGLVEIRPNRGARVAPLSP 79
|
|
| |
