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Conserved domains on  [gi|827202871|ref|WP_047195084|]
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hypothetical protein [Schlegelella brevitalea]

Protein Classification

pilin; type II secretion system protein; pilin; type II secretion system protein; prepilin-type N-terminal cleavage/methylation domain-containing protein; prepilin-type N-terminal cleavage/methylation domain-containing protein; prepilin-type N-terminal cleavage/methylation domain-containing protein; type II secretion system protein; type II secretion system GspH family protein; type II secretion system protein; type II secretion system GspH family protein; type II secretion system protein; type II secretion system protein; pilus assembly PilX N-terminal domain-containing protein; pilus assembly PilX N-terminal domain-containing protein; pilus assembly PilX N-terminal domain-containing protein; pilus assembly protein; pilus assembly protein; pilus assembly protein( domain architecture ID 11468746)

pilin similar to fimbrial protein PilE, which is required for pilus biogenesis, as well as fimbrial protein PilA, which is responsible for the adhesive property of the pilus; type II secretion system protein similar to Pseudomonas aeruginosa type II secretion system protein H, which is involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins; required for the translocation of a variety of enzymes across the outer membrane; pilin similar to fimbrial protein PilE, which is required for pilus biogenesis, as well as fimbrial protein PilA, which is responsible for the adhesive property of the pilus; type II secretion system protein similar to Pseudomonas aeruginosa type II secretion system protein H, which is involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins; required for the translocation of a variety of enzymes across the outer membrane; prepilin-type N-terminal cleavage/methylation domain-containing protein resembles type IV pilins at the N-terminus; prepilin-type N-terminal cleavage/methylation domain-containing protein resembles type IV pilins at the N-terminus; prepilin-type N-terminal cleavage/methylation domain-containing protein resembles type IV pilins at the N-terminus; type II secretion system protein similar to Pseudomonas aeruginosa type II secretion system protein H, which is involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins; required for the translocation of a variety of enzymes across the outer membrane; type II secretion system GspH family protein similar to Pseudomonas aeruginosa type II secretion system protein H that is part of the system system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm; type II secretion system protein similar to Pseudomonas aeruginosa type II secretion system protein H, which is involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins; required for the translocation of a variety of enzymes across the outer membrane; type II secretion system GspH family protein similar to Pseudomonas aeruginosa type II secretion system protein H that is part of the system system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm; type II secretion system protein similar to Pseudomonas aeruginosa type II secretion system protein H, which is involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins; required for the translocation of a variety of enzymes across the outer membrane; type II secretion system protein similar to Pseudomonas aeruginosa type II secretion system protein H, which is involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins; required for the translocation of a variety of enzymes across the outer membrane; pilus assembly PilX N-terminal domain-containing protein similar to the N-terminal region of Pseudomonas aeruginosa type 4 fimbrial biogenesis protein PilX; pilus assembly PilX N-terminal domain-containing protein similar to the N-terminal region of Pseudomonas aeruginosa type 4 fimbrial biogenesis protein PilX; pilus assembly PilX N-terminal domain-containing protein similar to the N-terminal region of Pseudomonas aeruginosa type 4 fimbrial biogenesis protein PilX; pilus assembly protein PilX is essential for bacterial aggregation and adhesion, similar to Neisseria meningitidis pilin PilX which is responsible for type IV pilus conformational changes associated with signaling to endothelial cells; pilus assembly protein PilX is essential for bacterial aggregation and adhesion, similar to Neisseria meningitidis pilin PilX which is responsible for type IV pilus conformational changes associated with signaling to endothelial cells; pilus assembly protein PilX is essential for bacterial aggregation and adhesion, similar to Neisseria meningitidis pilin PilX which is responsible for type IV pilus conformational changes associated with signaling to endothelial cells

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PilX COG4726
Type IV pilus assembly protein PilX [Cell motility, Extracellular structures];
5-60 3.52e-10

Type IV pilus assembly protein PilX [Cell motility, Extracellular structures];


:

Pssm-ID: 443761 [Multi-domain]  Cd Length: 175  Bit Score: 55.88  E-value: 3.52e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 827202871   5 RRAEQGVVLITVMIFLLLITVFSLSMFRASTTNVQVTGNMQMRQEALHAATIAVEE 60
Cdd:COG4726   10 PRRQRGAALIVALILLLVLTLLGVAAMRSSLLEERMAGNLRDRQLAFQAAEAALRD 65
 
Name Accession Description Interval E-value
PilX COG4726
Type IV pilus assembly protein PilX [Cell motility, Extracellular structures];
5-60 3.52e-10

Type IV pilus assembly protein PilX [Cell motility, Extracellular structures];


Pssm-ID: 443761 [Multi-domain]  Cd Length: 175  Bit Score: 55.88  E-value: 3.52e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 827202871   5 RRAEQGVVLITVMIFLLLITVFSLSMFRASTTNVQVTGNMQMRQEALHAATIAVEE 60
Cdd:COG4726   10 PRRQRGAALIVALILLLVLTLLGVAAMRSSLLEERMAGNLRDRQLAFQAAEAALRD 65
T2SS_GspK NF037980
type II secretion system minor pseudopilin GspK;
8-80 9.10e-03

type II secretion system minor pseudopilin GspK;


Pssm-ID: 468299 [Multi-domain]  Cd Length: 311  Bit Score: 35.73  E-value: 9.10e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 827202871   8 EQGVVLITVMIFLLLITVFSLSMFRASTTNVQVTGNMQMRQEALHAAtIAVEEtlsnnlFAK---QTARVASSPVD 80
Cdd:NF037980   1 QRGVALITVLLIVALVAVLAAGMLERQQLQVRRTENQQAQQQARWYA-LGAEA------LARlllRDDLRDDSDVD 69
 
Name Accession Description Interval E-value
PilX COG4726
Type IV pilus assembly protein PilX [Cell motility, Extracellular structures];
5-60 3.52e-10

Type IV pilus assembly protein PilX [Cell motility, Extracellular structures];


Pssm-ID: 443761 [Multi-domain]  Cd Length: 175  Bit Score: 55.88  E-value: 3.52e-10
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 827202871   5 RRAEQGVVLITVMIFLLLITVFSLSMFRASTTNVQVTGNMQMRQEALHAATIAVEE 60
Cdd:COG4726   10 PRRQRGAALIVALILLLVLTLLGVAAMRSSLLEERMAGNLRDRQLAFQAAEAALRD 65
PulK COG3156
Type II secretory pathway, component PulK [Intracellular trafficking, secretion, and vesicular ...
1-54 1.97e-07

Type II secretory pathway, component PulK [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442390 [Multi-domain]  Cd Length: 307  Bit Score: 49.23  E-value: 1.97e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 827202871   1 MKSPRRAEQGVVLITVMIFLLLITVFSLSMFRASTTNVQVTGNMQMRQEALHAA 54
Cdd:COG3156    1 MSRRRRRQRGVALITVLLIVALLAALAAALAERQRLELRRAENLLDRQQARWYA 54
T2SS_GspK NF037980
type II secretion system minor pseudopilin GspK;
8-80 9.10e-03

type II secretion system minor pseudopilin GspK;


Pssm-ID: 468299 [Multi-domain]  Cd Length: 311  Bit Score: 35.73  E-value: 9.10e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 827202871   8 EQGVVLITVMIFLLLITVFSLSMFRASTTNVQVTGNMQMRQEALHAAtIAVEEtlsnnlFAK---QTARVASSPVD 80
Cdd:NF037980   1 QRGVALITVLLIVALVAVLAAGMLERQQLQVRRTENQQAQQQARWYA-LGAEA------LARlllRDDLRDDSDVD 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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