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Conserved domains on  [gi|827202881|ref|WP_047195094|]
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hypothetical protein [Schlegelella brevitalea]

Protein Classification

Rossmann-fold NAD(P)-binding domain-containing protein( domain architecture ID 229380)

Rossmann-fold NAD(P)-binding domain-containing protein may function as an oxidoreductase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NADB_Rossmann super family cl21454
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ...
 1-232 1.05e-39

Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.


The actual alignment was detected with superfamily member PRK01713:

Pssm-ID: 473865 [Multi-domain]  Cd Length: 334  Bit Score: 140.89  E-value: 1.05e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   1 MPYSnpvLPHRKLWSVESLAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLALWSADPAGSRGDVVHDAALELGAQVAR 80
Cdd:PRK01713   1 MAFN---LKNRHLLSLVNHTEREIKYLLDLSRDLKRAKYAGTEQQRLKGKNIALIFEKTSTRTRCAFEVAAYDQGAQVTY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  81 LHPGHAAMSSHDEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQERTGKPLGQL 160
Cdd:PRK01713  78 IDPNSSQIGHKESMKDTARVLGRMYDAIEYRGFKQSIVNELAEYAGVPVFNGLTDEFHPTQMLADVLTMIENCDKPLSEI 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 827202881 161 RVALVGDPRRPCADALLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEADIV 232
Cdd:PRK01713 158 SYVYIGDARNNMGNSLLLIGAKLGMDVRICAPKALLPEASLVEMCEKFAKESGARITVTDDIDKAVKGVDFV 229
 
Name Accession Description Interval E-value
PRK01713 PRK01713
ornithine carbamoyltransferase; Provisional
 1-232 1.05e-39

ornithine carbamoyltransferase; Provisional


Pssm-ID: 167263 [Multi-domain]  Cd Length: 334  Bit Score: 140.89  E-value: 1.05e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   1 MPYSnpvLPHRKLWSVESLAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLALWSADPAGSRGDVVHDAALELGAQVAR 80
Cdd:PRK01713   1 MAFN---LKNRHLLSLVNHTEREIKYLLDLSRDLKRAKYAGTEQQRLKGKNIALIFEKTSTRTRCAFEVAAYDQGAQVTY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  81 LHPGHAAMSSHDEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQERTGKPLGQL 160
Cdd:PRK01713  78 IDPNSSQIGHKESMKDTARVLGRMYDAIEYRGFKQSIVNELAEYAGVPVFNGLTDEFHPTQMLADVLTMIENCDKPLSEI 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 827202881 161 RVALVGDPRRPCADALLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEADIV 232
Cdd:PRK01713 158 SYVYIGDARNNMGNSLLLIGAKLGMDVRICAPKALLPEASLVEMCEKFAKESGARITVTDDIDKAVKGVDFV 229
orni_carb_tr TIGR00658
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ...
 11-237 9.03e-37

ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]


Pssm-ID: 129743 [Multi-domain]  Cd Length: 304  Bit Score: 132.09  E-value: 9.03e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   11 RKLWSVESLAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLALWSADPAgSRGDVVHD-AALELGAQVARLHPGHAAMS 89
Cdd:TIGR00658   1 RHLLSLLDLSPEEIRYLLQLAKKLKKGKKKGKEHKKLKGKTLALIFEKPS-TRTRVSFEvAAYQLGGHPLYLNPNDLQLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   90 SHDEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQERTGKpLGQLRVALVGDPR 169
Cdd:TIGR00658  80 RGESIKDTARVLSRYVDGIMARVYKHEDVEELAKYASVPVINGLTDLFHPCQALADLLTIIEHFGK-LKGVKVVYVGDGN 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 827202881  170 RPCADaLLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEADIVVdaTD 237
Cdd:TIGR00658 159 NVCNS-LMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKENGGSVELTHDPVEAVKGADVIY--TD 223
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
 19-237 6.84e-34

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 124.78  E-value: 6.84e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  19 LAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLALWSADPagS---RG--DVvhdAALELGAQVARLHPGHAAMSSHDE 93
Cdd:COG0078   14 LTPEELRALLDLAAELKAKRKAGIPHRPLKGKTLAMIFEKP--StrtRVsfEV---GMAQLGGHAIYLDPGDSQLGRGES 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  94 VHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQERTGKpLGQLRVALVGDPRRpCA 173
Cdd:COG0078   89 IKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGK-LKGLKVAYVGDGNN-VA 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 827202881 174 DALLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEADIVVdaTD 237
Cdd:COG0078  167 NSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHDPAEAVKGADVVY--TD 228
OTCace_N pfam02729
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
15-151 2.05e-17

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;


Pssm-ID: 460665 [Multi-domain]  Cd Length: 140  Bit Score: 76.70  E-value: 2.05e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   15 SVESLAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLALW------------SAdpagsrgdvvhdAALELGAQVARLH 82
Cdd:pfam02729   4 SLEDLSREEIEALLDLAAELKEARKRGKKLPLLKGKTVALLfeepstrtrvsfEV------------AAKRLGGHVIYLS 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 827202881   83 PGHAAMSSHDEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQE 151
Cdd:pfam02729  72 SSDIQLSSGESLADTARVLSRYVDAIVIRHFGHEDLEELAEYASVPVINAGGDHEHPTQALADLLTIRE 140
 
Name Accession Description Interval E-value
PRK01713 PRK01713
ornithine carbamoyltransferase; Provisional
 1-232 1.05e-39

ornithine carbamoyltransferase; Provisional


Pssm-ID: 167263 [Multi-domain]  Cd Length: 334  Bit Score: 140.89  E-value: 1.05e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   1 MPYSnpvLPHRKLWSVESLAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLALWSADPAGSRGDVVHDAALELGAQVAR 80
Cdd:PRK01713   1 MAFN---LKNRHLLSLVNHTEREIKYLLDLSRDLKRAKYAGTEQQRLKGKNIALIFEKTSTRTRCAFEVAAYDQGAQVTY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  81 LHPGHAAMSSHDEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQERTGKPLGQL 160
Cdd:PRK01713  78 IDPNSSQIGHKESMKDTARVLGRMYDAIEYRGFKQSIVNELAEYAGVPVFNGLTDEFHPTQMLADVLTMIENCDKPLSEI 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 827202881 161 RVALVGDPRRPCADALLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEADIV 232
Cdd:PRK01713 158 SYVYIGDARNNMGNSLLLIGAKLGMDVRICAPKALLPEASLVEMCEKFAKESGARITVTDDIDKAVKGVDFV 229
PRK02102 PRK02102
ornithine carbamoyltransferase; Validated
 5-237 1.97e-39

ornithine carbamoyltransferase; Validated


Pssm-ID: 179366 [Multi-domain]  Cd Length: 331  Bit Score: 139.64  E-value: 1.97e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   5 NPVLPHRKLWSVESLAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLALWSADPAgSRG----DVvhdAALELGAQVAR 80
Cdd:PRK02102   2 AFNLKGRSFLKLLDFTPEEIEYLIDLSIELKAAKKAGIEHQYLEGKNIALIFEKTS-TRTrcafEV---AAIDLGAHVTY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  81 LHPGHAAMSSHDEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQERTGkPLGQL 160
Cdd:PRK02102  78 LGPNDSQLGKKESIEDTARVLGRMYDGIEYRGFKQEIVEELAKYSGVPVWNGLTDEWHPTQMLADFMTMKEHFG-PLKGL 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 827202881 161 RVALVGDPRRPCADALLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEADIVvdATD 237
Cdd:PRK02102 157 KLAYVGDGRNNMANSLMVGGAKLGMDVRICAPKELWPEEELVALAREIAKETGAKITITEDPEEAVKGADVI--YTD 231
orni_carb_tr TIGR00658
ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in ...
 11-237 9.03e-37

ornithine carbamoyltransferase; This family of ornithine carbamoyltransferases (OTCase) is in a superfamily with the related enzyme aspartate carbamoyltransferase. Most known examples are anabolic, playing a role in arginine biosynthesis, but some are catabolic. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily. [Amino acid biosynthesis, Glutamate family]


Pssm-ID: 129743 [Multi-domain]  Cd Length: 304  Bit Score: 132.09  E-value: 9.03e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   11 RKLWSVESLAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLALWSADPAgSRGDVVHD-AALELGAQVARLHPGHAAMS 89
Cdd:TIGR00658   1 RHLLSLLDLSPEEIRYLLQLAKKLKKGKKKGKEHKKLKGKTLALIFEKPS-TRTRVSFEvAAYQLGGHPLYLNPNDLQLG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   90 SHDEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQERTGKpLGQLRVALVGDPR 169
Cdd:TIGR00658  80 RGESIKDTARVLSRYVDGIMARVYKHEDVEELAKYASVPVINGLTDLFHPCQALADLLTIIEHFGK-LKGVKVVYVGDGN 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 827202881  170 RPCADaLLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEADIVVdaTD 237
Cdd:TIGR00658 159 NVCNS-LMLAGAKLGMDVVVATPEGYEPDADIVKKAQEIAKENGGSVELTHDPVEAVKGADVIY--TD 223
PRK03515 PRK03515
ornithine carbamoyltransferase subunit I; Provisional
 21-230 1.08e-36

ornithine carbamoyltransferase subunit I; Provisional


Pssm-ID: 179587 [Multi-domain]  Cd Length: 336  Bit Score: 132.92  E-value: 1.08e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  21 PDDVLQLLETARRLKQAARAGRPSVPLRGRNLAL-WSADPAGSRG--DVvhdAALELGAQVARLHPGHAAMSSHDEVHHT 97
Cdd:PRK03515  17 PAELNSLLQLAAKLKADKKNGKEEQKLTGKNIALiFEKDSTRTRCsfEV---AAYDQGARVTYLGPSGSQIGHKESIKDT 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  98 AQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQERT-GKPLGQLRVALVGDPRRPCADAL 176
Cdd:PRK03515  94 ARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLpGKAFNEMTLAYAGDARNNMGNSL 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 827202881 177 LQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEAD 230
Cdd:PRK03515 174 LEAAALTGLDLRLVAPKACWPEAALVTECRALAQKNGGNITLTEDIAEGVKGAD 227
PRK12562 PRK12562
ornithine carbamoyltransferase subunit F; Provisional
 10-232 1.32e-36

ornithine carbamoyltransferase subunit F; Provisional


Pssm-ID: 105755  Cd Length: 334  Bit Score: 132.49  E-value: 1.32e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  10 HRKLWSVESLAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLAL-WSADPAGSRGDVvHDAALELGAQVARLHPGHAAM 88
Cdd:PRK12562   6 KKHFLKLLDFTPAELNSLLQLAAKLKADKKNGKEVARLTGKNIALiFEKDSTRTRCSF-EVAAYDQGARVTYLGPSGSQI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  89 SSHDEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQER-TGKPLGQLRVALVGD 167
Cdd:PRK12562  85 GHKESIKDTARVLGRMYDGIQYRGHGQEVVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHlPGKAFNEMTLVYAGD 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 827202881 168 PRRPCADALLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEADIV 232
Cdd:PRK12562 165 ARNNMGNSMLEAAALTGLDLRLVAPQACWPEASLVAECSALAQKHGGKITLTEDIAAGVKGADFI 229
PRK04284 PRK04284
ornithine carbamoyltransferase; Provisional
 8-232 1.68e-34

ornithine carbamoyltransferase; Provisional


Pssm-ID: 235269 [Multi-domain]  Cd Length: 332  Bit Score: 126.78  E-value: 1.68e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   8 LPHRKLWSVESLAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLAL-WSADPAGSRGdVVHDAALELGAQVARLHPGHA 86
Cdd:PRK04284   4 LRNRSFLTLLDFTPKEIEYLLDLSEDLKRAKYAGIEVQKLKGKNIALiFEKDSTRTRC-AFEVAAYDQGAHVTYLGPTGS 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  87 AMSSHDEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQERTGKPLGQLRVALVG 166
Cdd:PRK04284  83 QMGKKESTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEHLKKPYKDIKFTYVG 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 827202881 167 DPRRPCADALLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEADIV 232
Cdd:PRK04284 163 DGRNNVANALMQGAAIMGMDFHLVCPKELNPDDELLNKCKEIAAETGGKITITDDIDEGVKGSDVI 228
ArgF COG0078
Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine ...
 19-237 6.84e-34

Ornithine carbamoyltransferase [Amino acid transport and metabolism]; Ornithine carbamoyltransferase is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 439848 [Multi-domain]  Cd Length: 310  Bit Score: 124.78  E-value: 6.84e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  19 LAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLALWSADPagS---RG--DVvhdAALELGAQVARLHPGHAAMSSHDE 93
Cdd:COG0078   14 LTPEELRALLDLAAELKAKRKAGIPHRPLKGKTLAMIFEKP--StrtRVsfEV---GMAQLGGHAIYLDPGDSQLGRGES 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  94 VHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQERTGKpLGQLRVALVGDPRRpCA 173
Cdd:COG0078   89 IKDTARVLSRYVDGIMIRTFGHETLEELAKYAGVPVINGLTDLFHPCQALADLLTIREHFGK-LKGLKVAYVGDGNN-VA 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 827202881 174 DALLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEADIVVdaTD 237
Cdd:COG0078  167 NSLLLAAAKLGMDVRIATPEGYEPDPEIVAKAKEIAAESGGSITITHDPAEAVKGADVVY--TD 228
PRK00779 PRK00779
ornithine carbamoyltransferase; Provisional
 19-237 9.41e-23

ornithine carbamoyltransferase; Provisional


Pssm-ID: 234835 [Multi-domain]  Cd Length: 304  Bit Score: 94.77  E-value: 9.41e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  19 LAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLALWsADPAGSRGDVVHDAAL-ELGaqvarlhpGHAAMSSHDE---- 93
Cdd:PRK00779  13 LSPEELEELLDLAAELKKKRKAGEPHPPLKGKTLAMI-FEKPSTRTRVSFEVGMaQLG--------GHAIFLSPRDtqlg 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  94 ----VHHTAQMLGRLYDALdceglpseMVRLVD--------RGAGVPVYNGLGSDEHPVRVLAELMGLQERTGKPLGqLR 161
Cdd:PRK00779  84 rgepIEDTARVLSRYVDAI--------MIRTFEhetleelaEYSTVPVINGLTDLSHPCQILADLLTIYEHRGSLKG-LK 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 827202881 162 VALVGDPRRPCAdALLQIAAMTGLDVRFVAPRAQWPEPVRLEqaqRLAGARGLRLQLIESLQQASDEADIVVdaTD 237
Cdd:PRK00779 155 VAWVGDGNNVAN-SLLLAAALLGFDLRVATPKGYEPDPEIVE---KIAKETGASIEVTHDPKEAVKGADVVY--TD 224
OTCace_N pfam02729
Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;
15-151 2.05e-17

Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;


Pssm-ID: 460665 [Multi-domain]  Cd Length: 140  Bit Score: 76.70  E-value: 2.05e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   15 SVESLAPDDVLQLLETARRLKQAARAGRPSVPLRGRNLALW------------SAdpagsrgdvvhdAALELGAQVARLH 82
Cdd:pfam02729   4 SLEDLSREEIEALLDLAAELKEARKRGKKLPLLKGKTVALLfeepstrtrvsfEV------------AAKRLGGHVIYLS 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 827202881   83 PGHAAMSSHDEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQE 151
Cdd:pfam02729  72 SSDIQLSSGESLADTARVLSRYVDAIVIRHFGHEDLEELAEYASVPVINAGGDHEHPTQALADLLTIRE 140
PRK04523 PRK04523
N-acetylornithine carbamoyltransferase; Reviewed
 8-232 1.36e-13

N-acetylornithine carbamoyltransferase; Reviewed


Pssm-ID: 235304 [Multi-domain]  Cd Length: 335  Bit Score: 69.39  E-value: 1.36e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881   8 LPHRKLWSVESLAPDDVLQLLETARRLKQaaraGRPSVPLRGRNLALWSADPAGSRGDVVHDAALELGAQVARLHPGH-- 85
Cdd:PRK04523   1 MSLKHFLNTQDWSRAELDALLTQAAAFKR----NKLGSALKGKSIALVFFNPSLRTRTSFELGAFQLGGHAVVLQPGKda 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  86 --------AAMSSHDEVH--HTAQMLGRLYDALDCEGLPS----------EMVRLVDRGAGVPVYNgLGSDEHPVRVLAE 145
Cdd:PRK04523  77 wpiefelgAVMDGETEEHirEVARVLSRYVDLIGVRAFPKfvdwskdrqdQVLNSFAKYSTVPVIN-METITHPCQELAH 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881 146 LMGLQERTGKPLGQLRVALVGDPR-RP----CADALLQIAAMTGLDVRFVAPRAQWP-EPVRLEQAQRLAGARGLRLQLI 219
Cdd:PRK04523 156 ALALQEHFGTTLRGKKYVLTWTYHpKPlntaVANSALLIATRLGMDVTLLCPTPDYIlDERYMDWAEQNAAESGGSLTVS 235

                        250
                 ....*....|...
gi 827202881 220 ESLQQASDEADIV 232
Cdd:PRK04523 236 HDIDSAYAGADVV 248
PLN02342 PLN02342
ornithine carbamoyltransferase
 15-264 3.60e-10

ornithine carbamoyltransferase


Pssm-ID: 177976 [Multi-domain]  Cd Length: 348  Bit Score: 59.42  E-value: 3.60e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  15 SVESLAPDDVLQLLETARRLKQAARAG-RPSVPLRGRNLALWSADPAgSRGDVVHDAALE-LGAQVARLHPGHAAMSSHD 92
Cdd:PLN02342  50 HIDDFDKEEILGLLDRAKEVKALLKSGdRSFQPFKGKSMAMIFTKPS-MRTRVSFETGFFlLGGHALYLGPDDIQLGKRE 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  93 EVHHTAQMLGRLYDALdceglpseMVRL--------VDRGAGVPVYNGLGSDEHPVRVLAELMGLQERTGKPLGqLRVAL 164
Cdd:PLN02342 129 ETRDIARVLSRYNDII--------MARVfahqdvldLAEYSSVPVINGLTDYNHPCQIMADALTIIEHIGRLEG-TKVVY 199

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881 165 VGDPRRPCADaLLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRlAGarglrlqlIESLQQASDEADIVVDA----TDPlr 240
Cdd:PLN02342 200 VGDGNNIVHS-WLLLAAVLPFHFVCACPKGYEPDAKTVEKARA-AG--------ISKIEITNDPAEAVKGAdvvyTDV-- 267

                        250       260
                 ....*....|....*....|....
gi 827202881 241 WrteapaAGADEREHADNRRYTLQ 264
Cdd:PLN02342 268 W------ASMGQKEEAEKRKKAFQ 285
PRK14805 PRK14805
ornithine carbamoyltransferase; Provisional
 13-218 3.83e-09

ornithine carbamoyltransferase; Provisional


Pssm-ID: 237819 [Multi-domain]  Cd Length: 302  Bit Score: 56.23  E-value: 3.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  13 LWSVESLAPDDVLQLLETARRLKQAARAGRPSvpLRGRNLALWSADPAgSRGDVVHDAAL-ELGAQVARLHPGHAAMSSH 91
Cdd:PRK14805   4 LLSIKELTQQQLLDLLALAKTIKANPAEYRQA--LAGKSVVMLFEKPS-LRTRVSFDIGInKLGGHCLYLDQQNGALGKR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  92 DEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQERTGKpLGQLRVALVGDPRRp 171
Cdd:PRK14805  81 ESVADFAANLSCWADAIVARVFSHSTIEQLAEHGSVPVINALCDLYHPCQALADFLTLAEQFGD-VSKVKLAYVGDGNN- 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 827202881 172 CADALLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQL 218
Cdd:PRK14805 159 VTHSLMYGAAILGATMTVICPPGHFPDGQIVAEAQELAAKSGGKLVL 205
OTCace pfam00185
Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;
161-241 8.89e-07

Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;


Pssm-ID: 425511 [Multi-domain]  Cd Length: 154  Bit Score: 47.60  E-value: 8.89e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  161 RVALVGDPRRPCADALLQIAAMTGLDVRFVAPRAQWPEPVRLEQAQRLAGARGLRLQLIESLQQASDEADIVVdaTDplR 240
Cdd:pfam00185   1 KIAYVGDGHNNVAHSLIIAAAKLGMDVRLATPKGYPPDPEVLDKAKKIAEKSGGSIEITDDPAEAVKGADVVY--TD--V 76


                  .
gi 827202881  241 W 241
Cdd:pfam00185  77 W 77
PRK14804 PRK14804
ornithine carbamoyltransferase; Provisional
 11-236 4.32e-04

ornithine carbamoyltransferase; Provisional


Pssm-ID: 173265 [Multi-domain]  Cd Length: 311  Bit Score: 41.17  E-value: 4.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  11 RKLWSVESLAPDDVLQLLETARRLKQ--AARAGRPSvplrGRNLALWSADPAgSRGDVVHDAAL-ELGaqvarlhpGHAA 87
Cdd:PRK14804   7 KHLISWEDWSDSEILDLLDFAVHVKKnrVNYAGHMS----GRSLAMLFQKTS-TRTRVSFEVAMtEMG--------GHGI 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 827202881  88 ----MSSH---DEVHHTAQMLGRLYDALDCEGLPSEMVRLVDRGAGVPVYNGLGSDEHPVRVLAELMGLQ-ERTGKPLGQ 159
Cdd:PRK14804  74 yldwMASNfqlSDIDLEARYLSRNVSVIMARLKKHEDLLVMKNGSQVPVINGCDNMFHPCQSLADIMTIAlDSPEIPLNQ 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 827202881 160 LRVALVGdPRRPCADALLQIAAMTGLDVRFVAPRAQwPEPVRLEQAQRlAGARGlRLQLIESLQQASDEADIVVDAT 236
Cdd:PRK14804 154 KQLTYIG-VHNNVVNSLIGITAALGIHLTLVTPIAA-KENIHAQTVER-AKKKG-TLSWEMNLHKAVSHADYVYTDT 226
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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