|
Name |
Accession |
Description |
Interval |
E-value |
| ubiA_proteo |
TIGR01474 |
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ... |
10-288 |
2.68e-109 |
|
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 130539 Cd Length: 281 Bit Score: 317.72 E-value: 2.68e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 10 LLAYHRLMRTDKPIGALLLLWPTLWALWVATP--GVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLP 87
Cdd:TIGR01474 1 LLPYAKLMRADKPIGTLLLLWPCLWSLLLAAQagGIPPLYLLGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 88 SGQVTGKEARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPL 167
Cdd:TIGR01474 81 SGAVSVRQAILFLLVQLLVALGVLLQLNPLTILLGVASLALVATYPFMKRITYWPQLVLGLAFGWGALMGWAAVTGDLST 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 168 SCWLMFLANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAG 247
Cdd:TIGR01474 161 AAWVLYLANILWTLGYDTIYAMQDKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLALAGLIAGLGPVYYLGLAAAA 240
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 829778633 248 LLFAYQQKLIAKRERDACFKAFMNNNYVGLVLFLGLAMGYF 288
Cdd:TIGR01474 241 LLLIRQIATLDIRDPENCLKLFKANNYVGLLLFAGIALGWL 281
|
|
| PT_UbiA_COQ2 |
cd13959 |
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ... |
17-286 |
2.35e-103 |
|
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260122 [Multi-domain] Cd Length: 272 Bit Score: 302.46 E-value: 2.35e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 17 MRTDKPIGALLLLWPTLWALWVATPGVPP--LWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQVTGK 94
Cdd:cd13959 1 MRLDKPIGTLLLLPPALWGLLLAAGGLPLplLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 95 EARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSCWLMFL 174
Cdd:cd13959 81 EALLFLAVQLLLGLALLLQLNPLTILLSPIALLLVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSLPLPALLLYL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 175 ANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLLFAYQQ 254
Cdd:cd13959 161 AVIFWTAGYDTIYAHQDREDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGLGWPYYLGLGAAAHLLWQEH 240
|
250 260 270
....*....|....*....|....*....|..
gi 829778633 255 KLIAKRERDACFKAFMNNNYVGLVLFLGLAMG 286
Cdd:cd13959 241 RLDLPDPLRSCLAFFLSNGWVGLLLFAGLLLD 272
|
|
| UbiA |
COG0382 |
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ... |
11-285 |
2.10e-84 |
|
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 440151 Cd Length: 280 Bit Score: 254.38 E-value: 2.10e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 11 LAYHRLMRTDKPIGALLLLWPTLWALWVATPGVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQ 90
Cdd:COG0382 1 RAYLRLLRLDRPIGILLLLWPTLWALFLAAGGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLASGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 91 VTGKEARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYP-FMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSC 169
Cdd:COG0382 81 ISLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSlFLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPLSA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 170 WLMFLANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKL-IIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAGL 248
Cdd:COG0382 161 WLLALAAFLWTLAYDTIYDLEDREGDRKIGIKTLAILFGVRDALiIAGVLYALAVLLLLLLGLLAGLGLLYLLGLLAALL 240
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 829778633 249 L-FAYQQKLIAKRERD--ACFKAFMNNNYVGLVLFLGLAM 285
Cdd:COG0382 241 LlYLSQLWLLRPRKKDpaRALKLFKLNMLLGLLLFLGIAL 280
|
|
| PLN02809 |
PLN02809 |
4-hydroxybenzoate nonaprenyltransferase |
13-286 |
3.26e-55 |
|
4-hydroxybenzoate nonaprenyltransferase
Pssm-ID: 178405 Cd Length: 289 Bit Score: 180.27 E-value: 3.26e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 13 YHRLMRTDKPIGALLLLWPTLWALWVAT-PGVPP-LWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQ 90
Cdd:PLN02809 9 YAKLARLDKPIGTWLLAWPCMWSIALAApPGSLPdLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTKLRPIASGA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 91 VTGKEARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESL-PLSC 169
Cdd:PLN02809 89 LTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASSLLLVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVKGSLdPAVV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 170 WLMFLANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLL 249
Cdd:PLN02809 169 LPLYASGVCWTLVYDTIYAHQDKEDDLKVGVKSTALRFGDDTKLWLTGFGAASIGGLALSGYNAGLGWPYYAGLAAAAGH 248
|
250 260 270
....*....|....*....|....*....|....*..
gi 829778633 250 FAYQQKLIAKRERDACFKAFMNNNYVGLVLFLGLAMG 286
Cdd:PLN02809 249 LAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAGIVLG 285
|
|
| UbiA |
pfam01040 |
UbiA prenyltransferase family; |
28-271 |
1.31e-52 |
|
UbiA prenyltransferase family;
Pssm-ID: 460038 [Multi-domain] Cd Length: 250 Bit Score: 172.03 E-value: 1.31e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 28 LLWPTLWALWVATPGVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQVTGKEARVLFIVLVLLS 107
Cdd:pfam01040 1 LLIPALAGLALAAGGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLALG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 108 FLLVLTLNTMTILLSVAALALAWVYP-FMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSCWLMFLANILWAVAYDTQ 186
Cdd:pfam01040 81 LLLLLLLNPLTALLGLAALLLYVLYTlRLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWTWAIALA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 187 YAMVDRDDDLKIGIKSTAILFGRQDKLIIG-ILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLLFAYQQKLIAKRERDAC 265
Cdd:pfam01040 161 NDLRDREDDRKAGIKTLPVVLGRKAARILLaLLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDPKKD 240
|
....*.
gi 829778633 266 FKAFMN 271
Cdd:pfam01040 241 AKAFFF 246
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| ubiA_proteo |
TIGR01474 |
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ... |
10-288 |
2.68e-109 |
|
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 130539 Cd Length: 281 Bit Score: 317.72 E-value: 2.68e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 10 LLAYHRLMRTDKPIGALLLLWPTLWALWVATP--GVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLP 87
Cdd:TIGR01474 1 LLPYAKLMRADKPIGTLLLLWPCLWSLLLAAQagGIPPLYLLGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 88 SGQVTGKEARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPL 167
Cdd:TIGR01474 81 SGAVSVRQAILFLLVQLLVALGVLLQLNPLTILLGVASLALVATYPFMKRITYWPQLVLGLAFGWGALMGWAAVTGDLST 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 168 SCWLMFLANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAG 247
Cdd:TIGR01474 161 AAWVLYLANILWTLGYDTIYAMQDKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLALAGLIAGLGPVYYLGLAAAA 240
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 829778633 248 LLFAYQQKLIAKRERDACFKAFMNNNYVGLVLFLGLAMGYF 288
Cdd:TIGR01474 241 LLLIRQIATLDIRDPENCLKLFKANNYVGLLLFAGIALGWL 281
|
|
| PT_UbiA_COQ2 |
cd13959 |
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ... |
17-286 |
2.35e-103 |
|
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260122 [Multi-domain] Cd Length: 272 Bit Score: 302.46 E-value: 2.35e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 17 MRTDKPIGALLLLWPTLWALWVATPGVPP--LWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQVTGK 94
Cdd:cd13959 1 MRLDKPIGTLLLLPPALWGLLLAAGGLPLplLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 95 EARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSCWLMFL 174
Cdd:cd13959 81 EALLFLAVQLLLGLALLLQLNPLTILLSPIALLLVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSLPLPALLLYL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 175 ANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLLFAYQQ 254
Cdd:cd13959 161 AVIFWTAGYDTIYAHQDREDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGLGWPYYLGLGAAAHLLWQEH 240
|
250 260 270
....*....|....*....|....*....|..
gi 829778633 255 KLIAKRERDACFKAFMNNNYVGLVLFLGLAMG 286
Cdd:cd13959 241 RLDLPDPLRSCLAFFLSNGWVGLLLFAGLLLD 272
|
|
| UbiA |
COG0382 |
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ... |
11-285 |
2.10e-84 |
|
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 440151 Cd Length: 280 Bit Score: 254.38 E-value: 2.10e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 11 LAYHRLMRTDKPIGALLLLWPTLWALWVATPGVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQ 90
Cdd:COG0382 1 RAYLRLLRLDRPIGILLLLWPTLWALFLAAGGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLASGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 91 VTGKEARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYP-FMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSC 169
Cdd:COG0382 81 ISLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSlFLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPLSA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 170 WLMFLANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKL-IIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAGL 248
Cdd:COG0382 161 WLLALAAFLWTLAYDTIYDLEDREGDRKIGIKTLAILFGVRDALiIAGVLYALAVLLLLLLGLLAGLGLLYLLGLLAALL 240
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 829778633 249 L-FAYQQKLIAKRERD--ACFKAFMNNNYVGLVLFLGLAM 285
Cdd:COG0382 241 LlYLSQLWLLRPRKKDpaRALKLFKLNMLLGLLLFLGIAL 280
|
|
| PLN02809 |
PLN02809 |
4-hydroxybenzoate nonaprenyltransferase |
13-286 |
3.26e-55 |
|
4-hydroxybenzoate nonaprenyltransferase
Pssm-ID: 178405 Cd Length: 289 Bit Score: 180.27 E-value: 3.26e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 13 YHRLMRTDKPIGALLLLWPTLWALWVAT-PGVPP-LWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQ 90
Cdd:PLN02809 9 YAKLARLDKPIGTWLLAWPCMWSIALAApPGSLPdLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTKLRPIASGA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 91 VTGKEARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESL-PLSC 169
Cdd:PLN02809 89 LTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASSLLLVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVKGSLdPAVV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 170 WLMFLANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLL 249
Cdd:PLN02809 169 LPLYASGVCWTLVYDTIYAHQDKEDDLKVGVKSTALRFGDDTKLWLTGFGAASIGGLALSGYNAGLGWPYYAGLAAAAGH 248
|
250 260 270
....*....|....*....|....*....|....*..
gi 829778633 250 FAYQQKLIAKRERDACFKAFMNNNYVGLVLFLGLAMG 286
Cdd:PLN02809 249 LAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAGIVLG 285
|
|
| UbiA |
pfam01040 |
UbiA prenyltransferase family; |
28-271 |
1.31e-52 |
|
UbiA prenyltransferase family;
Pssm-ID: 460038 [Multi-domain] Cd Length: 250 Bit Score: 172.03 E-value: 1.31e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 28 LLWPTLWALWVATPGVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQVTGKEARVLFIVLVLLS 107
Cdd:pfam01040 1 LLIPALAGLALAAGGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLALG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 108 FLLVLTLNTMTILLSVAALALAWVYP-FMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSCWLMFLANILWAVAYDTQ 186
Cdd:pfam01040 81 LLLLLLLNPLTALLGLAALLLYVLYTlRLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALLLALALFLWTWAIALA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 187 YAMVDRDDDLKIGIKSTAILFGRQDKLIIG-ILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLLFAYQQKLIAKRERDAC 265
Cdd:pfam01040 161 NDLRDREDDRKAGIKTLPVVLGRKAARILLaLLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDPKKD 240
|
....*.
gi 829778633 266 FKAFMN 271
Cdd:pfam01040 241 AKAFFF 246
|
|
| ubiA |
PRK12873 |
4-hydroxybenzoate polyprenyltransferase; |
7-286 |
5.93e-36 |
|
4-hydroxybenzoate polyprenyltransferase;
Pssm-ID: 171787 [Multi-domain] Cd Length: 294 Bit Score: 130.17 E-value: 5.93e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 7 QSKLLAYHRLMRTDKPIGALLLLWPTLWALWVaTPGVPP-LWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRP 85
Cdd:PRK12873 4 SIKLSPWFELLRWNKPTGRLILLIPAGWSLWL-TPSAPPsLLLLLLIILGGLAVSGAGCIANDLWDRRIDRKVERTKNRP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 86 LPSGQVTGKEARVLFIVLVLLSFLLVLTLNT----MTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAV 161
Cdd:PRK12873 83 LARGKISLKTAYSLLIVLLLLSLFVVLSLPQpsrnLCLSLAFLALPPILIYPSAKRWFAYPQAILALCWGFAVLIPWAAA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 162 SESLP-----LSCWlmfLANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKLIIGI---LQVAVLALMVAIGRLN 233
Cdd:PRK12873 163 EGSLNggwplLFCW---LATLLWTFGFDTVYAMADRRDDAKIGLNSSALSLGSNALKTVQIcyfLTSIFLALAAFIAQVG 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 829778633 234 GLNWEFYwsvLVAGLLFayQQKLIAKRERDACFKA----FMNNNYVGLVLFLGLAMG 286
Cdd:PRK12873 240 FIFWPFW---LIASIGM--QRDILKLFPEKQSIKTignhFSNQVILGSLLLLGLILA 291
|
|
| ubiA |
PRK13106 |
prenyltransferase; Reviewed |
6-284 |
6.46e-29 |
|
prenyltransferase; Reviewed
Pssm-ID: 237283 Cd Length: 300 Bit Score: 111.74 E-value: 6.46e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 6 TQSKLLAYHRLMRTDKPIGALLLLWptLWALwVATPGVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRP 85
Cdd:PRK13106 11 TRSKFYIILRFLRIEQTFFSLPMAY--LGAF-VAIKGIPPISTLILIFLALFFLRTAGMTNDNLADLEIDAKNPRTKNRP 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 86 LPSGQVTGKEARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLG-----AAFGWSIP---MA 157
Cdd:PRK13106 88 LVTGAIKISEAKALITAGLILFFASAYLVNRWALLLSPIVALIAMSYPYMKRYTAFANYHLAsiqglAVFSGAVAvlgLY 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 158 FAAVSESLPLSCWLMFLANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKLIIGILQVAVLALMVAIGRLNGLNW 237
Cdd:PRK13106 168 ANSLIQVLLRVPWLFVIGTILWAAGFDLYNHIPDAEFDREMGLHSFAVVLGKWALTFAGLNQLFSVVLDLLGDLYYGLGP 247
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 829778633 238 EFYWSVLVAGLLFAYQQKLIAKreRDACFKAFMNNNYVGLVLFLGLA 284
Cdd:PRK13106 248 IAIAATILHGLIMAYAYYLASK--KGDFGRAFYYNIYSSIVLGLGII 292
|
|
| ubiA |
PRK12888 |
4-hydroxybenzoate octaprenyltransferase; |
33-281 |
1.27e-19 |
|
4-hydroxybenzoate octaprenyltransferase;
Pssm-ID: 183814 Cd Length: 284 Bit Score: 86.31 E-value: 1.27e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 33 LWALWVATPGVPPLWILGVFVAGVWLmRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQVTGKEARVLFIVLVLLSFLLVL 112
Cdd:PRK12888 26 LTAMFASDGSVHWADLLLVTVAMVGA-RTFAMAANRIIDREIDARNPRTAGRELVTGAVSVRTAWTGALVALAVFLGAAA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 113 TLNTMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSCWLMFLANILWAVAYDTQYAMVDR 192
Cdd:PRK12888 105 LLNPLCLALAPLAVAPLVVYPYAKRFTNFPHAILGLAQAVGPVGAWIAVTGTWSWPAVLLGLAVGLWIGGFDLIYACQDA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 193 DDDLKIGIKSTAILFGRQDKLIIG-ILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLLFAYQQKLIAKRERDACFKAF-M 270
Cdd:PRK12888 185 EVDRRIGVRSVPARFGVRAALWASrVAHVVTFALFVWFGLAVGFGALWWIGLAITAGAFAYEHAIVSPTDLSRVNRAFfT 264
|
250
....*....|.
gi 829778633 271 NNNYVGLVLFL 281
Cdd:PRK12888 265 ANGFVGIALFG 275
|
|
| ubiA |
PRK12886 |
prenyltransferase; Reviewed |
46-284 |
2.81e-16 |
|
prenyltransferase; Reviewed
Pssm-ID: 237247 Cd Length: 291 Bit Score: 77.04 E-value: 2.81e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 46 LWILGVFVAGvwlmRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQVtGKEARVLFIVL-VLLSFLLVLTLNTMTILLSVA 124
Cdd:PRK12886 45 DWILMAMVGA----RTAAMGFNRLIDAEIDARNPRTAGRAIPAGLI-SKGSAILFIVLsSLLMLFAAWFLNPLCLYLSPP 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 125 ALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSCWLMFLANILWAVAYDTQYAMVDRDDDLKIGIKSTA 204
Cdd:PRK12886 120 ALFFLLLYSYCKRFTALAHVVLGFCLALAPLGAWIAIRGTIELPAILLGLAVLFWVAGFDILYALQDLEFDRKEGLHSIP 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 205 ILFGRQDKLIIG-ILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLLFAYQQKLIAKRERDACFKAFMN-NNYVGLVLFLG 282
Cdd:PRK12886 200 AKLGVNGSLWIArVFHLLMIGFLFALGISAGLGPWFLAGLAVTGILLLYEHWLLRGGDLTRLDAAFFNmNGYISVTLFAA 279
|
..
gi 829778633 283 LA 284
Cdd:PRK12886 280 TL 281
|
|
| PT_UbiA |
cd13956 |
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ... |
15-284 |
3.54e-15 |
|
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260119 [Multi-domain] Cd Length: 271 Bit Score: 73.54 E-value: 3.54e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 15 RLMRTdkPIGALLLLWPTLWALWVATPGVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRtaGRPLPSGQVTGK 94
Cdd:cd13956 2 RLMRP--YTLLYVLAPALAGAALAGAFAGPLPALLLLALLAVFLGAGAGYALNDYTDRELDAINKP--DRPLPSGRLSPR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 95 EARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQ-VVLGAAFGWSIPMAFAAVSE-SLPLSCWLM 172
Cdd:cd13956 78 QALAFAAALLLVGLALALALGPLALLLLLAGLLLGLAYSLGLKRLKLGGwGVLGYATGLALLPGLGAVAAgGLVPLALLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 173 FLANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLLFAY 252
Cdd:cd13956 158 ALVFLLLGLGINLYNDLPDVEGDRAAGIRTLPVRLGPRRARRLAAGLLLAALILVVLLAVAGLLGPLALLALLAVALLAL 237
|
250 260 270
....*....|....*....|....*....|..
gi 829778633 253 QQKLIAKRERDACFKAFMNNNYVGLVLFLGLA 284
Cdd:cd13956 238 RARFARADRLPALPRGFLLLAVYRLLLFAALL 269
|
|
| PT_UbiA_Cox10 |
cd13957 |
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ... |
21-281 |
2.82e-14 |
|
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260120 Cd Length: 271 Bit Score: 70.93 E-value: 2.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 21 KPIGALLLLWPTLWALWVATPGVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQVTGKEARVL- 99
Cdd:cd13957 5 KPRITLLVLLTALAGYLLAPGGVPDLLLLLLTLLGTALVSASANALNQYIERDIDAKMKRTRNRPLPSGRISPKHALIFg 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 100 FIVLVLLSFLLVLTLNTMTILLSVAALAL-AWVYPFMKRYTHLPQVVLGAAFGwSIP--MAFAAVSESLPLSCWLMFLAN 176
Cdd:cd13957 85 LVLGILGLALLALFVNPLTALLGLLGIFLyVFVYTPLKKRTTPLNTVIGGIAG-AIPplIGWAAATGSLDLGAWLLFLIL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 177 ILWavaydtQY------AMVDRDDDLKIGIKSTAILFGRQD-KLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLL 249
Cdd:cd13957 164 FLW------QPphfwalAILYRDDYARAGIPMLPVVKGERRtKRQILLYTLLLVPLSLLLYLLGLTGWIYLVVALLLGLY 237
|
250 260 270
....*....|....*....|....*....|....
gi 829778633 250 FAYQ-QKLIAKRERDACFKAFMN-NNYVGLVLFL 281
Cdd:cd13957 238 FLYLaIKLYRSPDDKWARKLFFAsLIYLPLLFLL 271
|
|
| PRK04375 |
PRK04375 |
protoheme IX farnesyltransferase; Provisional |
27-179 |
5.73e-14 |
|
protoheme IX farnesyltransferase; Provisional
Pssm-ID: 235293 Cd Length: 296 Bit Score: 70.55 E-value: 5.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 27 LLLWPTLWALWVATPGVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQVTGKEARVL-FIVLVL 105
Cdd:PRK04375 24 LNLFTALGGMLLAPPGVPPLLLLLLTLLGIALVAGAAGALNNYIDRDIDAKMERTKNRPLVTGRISPREALIFgLVLGVL 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 829778633 106 LSFLLVLTLNTMTILLSVAALAL-AWVYP-FMKRYThlPQ-VVLGAAFGWSIPM-AFAAVSESLPLSCWLMFLANILW 179
Cdd:PRK04375 104 GFLLLGLFVNPLAAWLTLAGIFFyVVVYTlWLKRRT--PQnIVIGGAAGAMPPLiGWAAVTGSLSWEALILFLIIFLW 179
|
|
| ubiA |
PRK12874 |
4-hydroxybenzoate polyprenyltransferase; |
66-281 |
2.09e-10 |
|
4-hydroxybenzoate polyprenyltransferase;
Pssm-ID: 237242 Cd Length: 291 Bit Score: 60.02 E-value: 2.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 66 VNDYADRKFDGHVKRTAGRPLPSGQVTGKEARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYTHLPQVV 145
Cdd:PRK12874 66 FNRLVDRDIDKDNPRTANRPSVDGRISVKSMVLFIVLNALIFIGVSYFINPLAFKLSFPFLIVLGGYSYFKRFSSLAHLV 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 146 LGAAFGWSiPMAFA-AVSESLPLSCWLMFLANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKLIIGIL--QVAV 222
Cdd:PRK12874 146 LGLSLGLA-PIAGVvAVLGEIPLWSVFLALGVMFWVAGFDLLYSLQDMEFDKKRGLHSIPSKFGEKATLFISRLfhLLAV 224
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 829778633 223 LALMVAIGRLNGLNWEfYWSVLVAGLLFAYQQKLIAK--RERDACFkaFMNNNYVGLVLFL 281
Cdd:PRK12874 225 LFWLLFVWCAHLGLFA-YLGVIVSALILLYEHYLVRKdfKKIDKAF--FTLNGYLGIVFFI 282
|
|
| cyoE_ctaB |
TIGR01473 |
protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also ... |
27-283 |
4.31e-10 |
|
protoheme IX farnesyltransferase; This model describes protoheme IX farnesyltransferase, also called heme O synthase, an enzyme that creates an intermediate in the biosynthesis of heme A. Prior to the description of its enzymatic function, this protein was often called a cytochrome o ubiquinol oxidase assembly factor. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]
Pssm-ID: 273645 Cd Length: 280 Bit Score: 59.18 E-value: 4.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 27 LLLWPTLWALWVAT-PGVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQVTGKEARVL-FIVLV 104
Cdd:TIGR01473 14 LLLITAFAGMWLAPgGALVNPPLLLLTLLGTTLAAASANAFNMYIDRDIDKKMKRTRNRPLVTGRISPREALAFgLLLGV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 105 LLSFLLVLTLNTMT-ILLSVAALALAWVY-PFMKRYTHLpQVVLGAAFGwSIP--MAFAAVSESLPLSCWLMFLANILWA 180
Cdd:TIGR01473 94 LGVAILAAFVNPLAaLLGLFGIFFYVIVYtIWLKRRTPQ-NTVIGGFAG-AVPplIGWAAVTGSISLGAWLLFAIIFLWQ 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 181 VAYDTQYAMVDRDDDLKIGIKSTAILFG-RQDKLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLLFAYQQKLIAK 259
Cdd:TIGR01473 172 PPHFWALALKYKDDYRAAGIPMLPVVKGeRITKRQIALYTAALLPVSLLLAFLGGTGWLYLIVATLLGALFLYLAFKFYR 251
|
250 260
....*....|....*....|....*..
gi 829778633 260 --RERDACFKAFM-NNNYVGLVLFLGL 283
Cdd:TIGR01473 252 dpTDRKKARKLFKfSLIYLALLFVALL 278
|
|
| ubiA |
PRK12895 |
prenyltransferase; Reviewed |
45-286 |
5.94e-10 |
|
prenyltransferase; Reviewed
Pssm-ID: 237251 Cd Length: 286 Bit Score: 58.67 E-value: 5.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 45 PLWILGVFVAGVwLMRAAGCVVNDYADRKFDGHVKRTAGRPLPSGQVTGKEARVLFIVLVLLSFLLVLTLNTMTILLSVA 124
Cdd:PRK12895 36 PIKILLILIAAV-SARTSAMSINRIEGLRYDMINPRKKDWALVSGRIKMREAIAFTIIFIAIFEICTFLLNRLVFILSPI 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 125 ALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLP--LSCWLMFLANILWAVAYDTQYAMVDRDDDLKIGIKS 202
Cdd:PRK12895 115 VIFLFIIDPFLKRYTAWRHIYMGSIIGLGVLAGYLAVIPAFPynLLIYIIFISSSLWIAGFDIIYVIPDIEYDKINGLKT 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 203 TAILFGRQDKLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLLFAYQQKLIAKRERDACFKAFMN-NNYVGLVLFL 281
Cdd:PRK12895 195 IMNTYGIKNGLYISDIFHISSLILFWISGIYIRTLWYLAALIIIYTLVIYQHLIIDPRNPINKRMSFFNaNSFIGFVFLI 274
|
....*
gi 829778633 282 GLAMG 286
Cdd:PRK12895 275 GIILS 279
|
|
| ubiA |
PRK12876 |
prenyltransferase; Reviewed |
60-280 |
1.69e-09 |
|
prenyltransferase; Reviewed
Pssm-ID: 237244 Cd Length: 300 Bit Score: 57.45 E-value: 1.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 60 RAAGCVVNDYADRKFDGHVKRTAGRPLPSGQVTGKEARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFMKRYT 139
Cdd:PRK12876 60 RTVGIIVNQIIDCAIDKKNPRTSSRVLPAKLLSINFSMLLLTLCSFLFLSLCWLLNPLCFSLAVLSTLLMIIYPYTKRVT 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 140 HLPQVVLGAAFGWSIPMAFAAVSESlPLSCWLMFLANiLWAV-------AYDTQYAMVDRDDDLKIGIKSTAILFGRQDK 212
Cdd:PRK12876 140 FLCHWILGLVYYLAILMNFFAIIET-PLSFSLFCMAS-LWGIsfgmiiaANDIIYAIQDLEFDRKEGLFSIPARFGEKKA 217
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 829778633 213 LII--GILQVAVLALMvAIGRLNGLNWEFYWSVLVAGLLFAYQQK---LIAKRERDACFKAFMNNNYVGLVLF 280
Cdd:PRK12876 218 IRIasANLIASAIAYL-LIGYFVSNKKIFYLCSLVPLTVILKTIKhysLIDKKKSTLEQKFFLGNIYLALSFF 289
|
|
| ubiA |
PRK12884 |
prenyltransferase; Reviewed |
9-289 |
1.37e-08 |
|
prenyltransferase; Reviewed
Pssm-ID: 183812 Cd Length: 279 Bit Score: 54.58 E-value: 1.37e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 9 KLLAYHRLMRTDKPIGALLLLwptLWALWVATPGVPPLWILGVFVAGVWLMrAAGCVVNDYADRKFDgHVKRTAgRPLPS 88
Cdd:PRK12884 3 KMKAYLELLRPEHGLMAGIAV---VLGAIIALGGLPLDEALLGFLTAFFAS-GSANALNDYFDYEVD-RINRPD-RPIPS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 89 GQVTGKEARVLFIVLVLLSFLLVLTLNTMTILLSVAALALAWVYPFM-KRYTHLPQVVLGAAFGWSIPMAFAAVSESLPL 167
Cdd:PRK12884 77 GRISRREALLLAILLFILGLIAAYLISPLAFLVVILVSVLGILYNWKlKEYGLIGNLYVAFLTGMTFIFGGIAVGELNEA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 168 ScWLMFLANILWAVAYDTQYAMVDRDDDLKIGIKSTAILFGRQDKLIIGILQVAVLALMVAIGRLNG-LNWEFYWSVLVA 246
Cdd:PRK12884 157 V-ILLAAMAFLMTLGREIMKDIEDVEGDRLRGARTLAILYGEKIAGRIAAALFILAVLLSPLPYLFGiFNILYLAPVLVA 235
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 829778633 247 GLLFAYQ-QKLIAKRERDACFKAfMNNNYVGLVL-FLGLAMGYFL 289
Cdd:PRK12884 236 DLIFLYSaYSLLRSQDRETIRKV-RKITLTAMLLaLVAFALGAIT 279
|
|
| PT_UbiA_DGGGPS |
cd13961 |
Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate ... |
42-264 |
6.45e-05 |
|
Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Digeranylgeranylglyceryl phosphate synthase (DGGGPS) transfers a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate, as part of the isoprenoid ether lipid biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260124 Cd Length: 270 Bit Score: 43.65 E-value: 6.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 42 GVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDgHVKRTaGRPLPSGQVTGKEARVLFIVLVLLSFLLVLTLNTMTILL 121
Cdd:cd13961 30 LSLNDLELLLLFLSVFLIAAAGYIINDYFDVEID-RINKP-DRPIPSGRISRREALILSILLNALGLILAFLLSPLALLI 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 122 SVAALALAWVYP-FMKRYTHLPQVVLGAAFGWSIPMAFAAVSESLPLSCWL---MFLANILWAVAYDtqyaMVDRDDDLK 197
Cdd:cd13961 108 ALLNSLLLWLYShKLKRTPLIGNLLVALLTGLPFLFGGLAAGNLLLIILLLalfAFLITLGREIVKD----IEDVEGDRA 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 829778633 198 IGIKSTAILFGRQD-KLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVAGLLFAYQQKLIAKRERDA 264
Cdd:cd13961 184 EGARTLPIVYGIKKaKKIAALLLLLAILLSPLPYLLGGLGILYLILIIIADLLFLYSAIRLAKSPKDY 251
|
|
| PT_UbiA_UBIAD1 |
cd13962 |
1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Human UBIAD1 is an enzyme involved in the ... |
42-286 |
8.83e-05 |
|
1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Human UBIAD1 is an enzyme involved in the synthesis of MK-4. Menaquinones (MKs, also called bacterial forms) are one of the two forms of natural vitamin K, the other being the plant form, phylloquinone (PK). All forms of vitamin K have a 2-methyl-1,4-naphthoquinone (menadione; K3) ring structure in common. At the 3-position of the ring, PK has a phytyl side chain while MKs have several repeating prenyl units. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.
Pssm-ID: 260125 Cd Length: 283 Bit Score: 43.27 E-value: 8.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 42 GVPPLWILGVFVAGVWLMRAAGCVVNDYAD--RKFDGHVKRTAGRPLPSGQVTGKEAR----VLFIVLVLLSFLLVLTLN 115
Cdd:cd13962 28 GFFNWLLFLLALLAALLLQIGVNLANDYFDykKGTDTEPRSGPSRVLVSGLLSPRQVLraalVLLLLAALLGLYLVALGG 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 116 TMTILLSVAALALAWVY---PFMKRYTHLPQVVLGAAFGWSIPM-AFAAVSESLPLSCWLMFLANILWAVAydTQYA--M 189
Cdd:cd13962 108 WLLLLLGLLGILAGYFYtggPFPLSYRGLGELFVFLFFGLLAVLgTYYVQTGSLSWEVLLAALPLGLLIAA--ILLAnnI 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 190 VDRDDDLKIGIKSTAILFGRQD-KLIIGILQVAVLALMVAIGRLNGLNWEFYWSVLVagLLFAYQQKLIAKRERDACFKA 268
Cdd:cd13962 186 RDIEADRAAGKRTLAVRLGRKRaRRLYAALLLLAYLLLLLLVLLGLLPLWSLLALLS--LPLAIKLLRRLLRKADKPLLL 263
|
250
....*....|....*...
gi 829778633 269 FMNNNYVGLVLFLGLAMG 286
Cdd:cd13962 264 IALKLTALLTLLFGLLLA 281
|
|
| ubiA |
PRK12882 |
prenyltransferase; Reviewed |
12-101 |
2.24e-04 |
|
prenyltransferase; Reviewed
Pssm-ID: 183811 Cd Length: 276 Bit Score: 41.88 E-value: 2.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 829778633 12 AYHRLMRtdkPIGALLLLWPTLWALWVATPGVPPLWILGVFVAGVWLMRAAGCVVNDYADRKFDgHVKRtAGRPLPSGQV 91
Cdd:PRK12882 6 GYLELTR---PVNAVVAGVAAFIGAFIAGGILSSPSLTGLAFAAVFLATGAGNAINDYFDREID-RINR-PDRPIPSGAV 80
|
90
....*....|....
gi 829778633 92 TGKEAR----VLFI 101
Cdd:PRK12882 81 SPRGALafsiLLFA 94
|
|
| PT_UbiA_1 |
cd13964 |
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ... |
35-99 |
4.97e-03 |
|
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.
Pssm-ID: 260127 Cd Length: 282 Bit Score: 37.95 E-value: 4.97e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 829778633 35 ALWVATPGVPPLWILGVFVAGVwLMRAAGCVVNDYADRKFDGhVKRtAGRPLPSGQVTGKEARVL 99
Cdd:cd13964 21 AALAGGGLGPVLRLALLLLASV-LLYAAGMVLNDVFDAELDA-RER-PERPIPSGRVSRGAALAL 82
|
|
| PRK09573 |
PRK09573 |
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed |
48-101 |
7.91e-03 |
|
(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase; Reviewed
Pssm-ID: 181963 Cd Length: 279 Bit Score: 37.25 E-value: 7.91e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 829778633 48 ILGVFVagVWLMRAAGCVVNDYADRKFDGHVKrtAGRPLPSGQVTGKEARVLFI 101
Cdd:PRK09573 40 ILAALV--VFLVCAGGNVINDIYDIEIDKINK--PERPIPSGRISLKEAKIFSI 89
|
|
| |
