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Conserved domains on  [gi|835334993|ref|WP_047460746|]
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MULTISPECIES: DNA-3-methyladenine glycosylase I [Vibrio]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Adenine_glyco super family cl01059
Methyladenine glycosylase; The DNA-3-methyladenine glycosylase I is constitutively expressed ...
 53-127 3.23e-13

Methyladenine glycosylase; The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.


The actual alignment was detected with superfamily member pfam03352:

Pssm-ID: 470051  Cd Length: 177  Bit Score: 65.50  E-value: 3.23e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 835334993   53 FQSGISWDVVRKKWPNFEELFFQFRIEPLLMLSDEVWEQKAQDPKIIRHLAKVMSIPKNARMIYEARQEHGSFSE 127
Cdd:pfam03352  35 FQAGLSWITILKKREAFREAFDGFDPEKVAKYDEADIERLLADPGIIRNRLKIEAAINNARAFLKIQEEFGSFSD 109
 
Name Accession Description Interval E-value
Adenine_glyco pfam03352
Methyladenine glycosylase; The DNA-3-methyladenine glycosylase I is constitutively expressed ...
 53-127 3.23e-13

Methyladenine glycosylase; The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.


Pssm-ID: 460894  Cd Length: 177  Bit Score: 65.50  E-value: 3.23e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 835334993   53 FQSGISWDVVRKKWPNFEELFFQFRIEPLLMLSDEVWEQKAQDPKIIRHLAKVMSIPKNARMIYEARQEHGSFSE 127
Cdd:pfam03352  35 FQAGLSWITILKKREAFREAFDGFDPEKVAKYDEADIERLLADPGIIRNRLKIEAAINNARAFLKIQEEFGSFSD 109
Tag COG2818
3-methyladenine DNA glycosylase Tag [Replication, recombination and repair];
53-127 1.15e-12

3-methyladenine DNA glycosylase Tag [Replication, recombination and repair];


Pssm-ID: 442066  Cd Length: 191  Bit Score: 63.95  E-value: 1.15e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 835334993  53 FQSGISWDVVRKKWPNFEELFFQFRIEPLLMLSDEVWEQKAQDPKIIRHLAKVMSIPKNARMIYEARQEHGSFSE 127
Cdd:COG2818   44 FQAGLSWITILRKREAFRAAFDGFDPEKVAAYDEADVERLLADPGIIRNRLKIEATINNARAFLALQEEFGSFSA 118
PRK10353 PRK10353
DNA-3-methyladenine glycosylase I;
39-129 4.92e-09

DNA-3-methyladenine glycosylase I;


Pssm-ID: 182401  Cd Length: 187  Bit Score: 54.17  E-value: 4.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835334993  39 VPEDRWLSAFSMKVF---QSGISWDVVRKKWPNFEELFFQFRIEPLLMLSDEVWEQKAQDPKIIRHLAKVMSIPKNARMI 115
Cdd:PRK10353  23 VPETDSKKLFEMICLegqQAGLSWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAY 102

                         90
                 ....*....|....
gi 835334993 116 YEARQEHGSFSEMV 129
Cdd:PRK10353 103 LQMEQNGEPFADFV 116
 
Name Accession Description Interval E-value
Adenine_glyco pfam03352
Methyladenine glycosylase; The DNA-3-methyladenine glycosylase I is constitutively expressed ...
 53-127 3.23e-13

Methyladenine glycosylase; The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.


Pssm-ID: 460894  Cd Length: 177  Bit Score: 65.50  E-value: 3.23e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 835334993   53 FQSGISWDVVRKKWPNFEELFFQFRIEPLLMLSDEVWEQKAQDPKIIRHLAKVMSIPKNARMIYEARQEHGSFSE 127
Cdd:pfam03352  35 FQAGLSWITILKKREAFREAFDGFDPEKVAKYDEADIERLLADPGIIRNRLKIEAAINNARAFLKIQEEFGSFSD 109
Tag COG2818
3-methyladenine DNA glycosylase Tag [Replication, recombination and repair];
53-127 1.15e-12

3-methyladenine DNA glycosylase Tag [Replication, recombination and repair];


Pssm-ID: 442066  Cd Length: 191  Bit Score: 63.95  E-value: 1.15e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 835334993  53 FQSGISWDVVRKKWPNFEELFFQFRIEPLLMLSDEVWEQKAQDPKIIRHLAKVMSIPKNARMIYEARQEHGSFSE 127
Cdd:COG2818   44 FQAGLSWITILRKREAFRAAFDGFDPEKVAAYDEADVERLLADPGIIRNRLKIEATINNARAFLALQEEFGSFSA 118
PRK10353 PRK10353
DNA-3-methyladenine glycosylase I;
39-129 4.92e-09

DNA-3-methyladenine glycosylase I;


Pssm-ID: 182401  Cd Length: 187  Bit Score: 54.17  E-value: 4.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835334993  39 VPEDRWLSAFSMKVF---QSGISWDVVRKKWPNFEELFFQFRIEPLLMLSDEVWEQKAQDPKIIRHLAKVMSIPKNARMI 115
Cdd:PRK10353  23 VPETDSKKLFEMICLegqQAGLSWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAY 102

                         90
                 ....*....|....
gi 835334993 116 YEARQEHGSFSEMV 129
Cdd:PRK10353 103 LQMEQNGEPFADFV 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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