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Conserved domains on  [gi|835335030|ref|WP_047460768|]
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iron ABC transporter permease [Vibrio fluvialis]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 39-349 1.76e-82

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 252.68  E-value: 1.76e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  39 IMTGPSMLDASRVLNALLEFiglpfQVDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAEMQTLLNNPMASPYTLGMAAAA 118
Cdd:COG0609    2 LSLGAVPISLSDVLRALLGP-----DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 119 GFGAALMLYIGSLGMdnHYAVPLGAFLCCMLSACFLFALASM-RHITSGQLILAGIALLFLFQSLLSLVQFIASPELSQQ 197
Cdd:COG0609   77 ALGAVLAIVLGGGLS--ALGLPLAAFLGALLAALLVYLLARRgGGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 198 ILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLGEERAKSVGVNVQRLRLKILFIVAVMTATVTSFVGII 277
Cdd:COG0609  155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 835335030 278 GFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVIVPGALFPIGIVTAIIGVPFFFWLIVAKR 349
Cdd:COG0609  235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 39-349 1.76e-82

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 252.68  E-value: 1.76e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  39 IMTGPSMLDASRVLNALLEFiglpfQVDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAEMQTLLNNPMASPYTLGMAAAA 118
Cdd:COG0609    2 LSLGAVPISLSDVLRALLGP-----DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 119 GFGAALMLYIGSLGMdnHYAVPLGAFLCCMLSACFLFALASM-RHITSGQLILAGIALLFLFQSLLSLVQFIASPELSQQ 197
Cdd:COG0609   77 ALGAVLAIVLGGGLS--ALGLPLAAFLGALLAALLVYLLARRgGGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 198 ILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLGEERAKSVGVNVQRLRLKILFIVAVMTATVTSFVGII 277
Cdd:COG0609  155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 835335030 278 GFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVIVPGALFPIGIVTAIIGVPFFFWLIVAKR 349
Cdd:COG0609  235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 30-346 1.01e-64

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 207.38  E-value: 1.01e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030   30 ILLASFVLDIMTGPSMLDASRVLNALLEFIglpfqvDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAEMQTLLNNPMASP 109
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGD------DSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  110 YTLGMAAAAGFGAALMLYIGSLGmdNHYAVPLGAFLCCMLSACFLFALASMR-HITSGQLILAGIALLFLFQSLLSLVQF 188
Cdd:pfam01032  75 SILGISSGAALGAVLAILLGGSL--SLFALPLAAFIGALLAALLVYFLSRGRgGASPLRLILAGIAVSALLSALTSLLLL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  189 IASPELSQQILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLGEERAKSVGVNVQRLRLKILFIVAVMTA 268
Cdd:pfam01032 153 LLNPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTA 232

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 835335030  269 TVTSFVGIIGFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVIVPGALFPIGIVTAIIGVPFFFWLIV 346
Cdd:pfam01032 233 ASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLL 310
btuC PRK09535
cobalamin ABC transporter permease BtuC;
63-346 4.68e-40

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 144.89  E-value: 4.68e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  63 FQVDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAEMQTLLNNPMASPYTLGMAAAAGFGAALMLYIGSLGMdnhYAVPLG 142
Cdd:PRK09535  81 FAVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAVP---FGLQAA 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 143 AFLCCMLSACFLFALASMR-HITSGQLILAGIALLFLFQSLLSLVQFIASPELsQQILFWLFGSLSKATWSNLTITAVVV 221
Cdd:PRK09535 158 AFAGALVAAFGVYAIATENgRTPVATLLLAGVAVQTFLGAVISYLLLHSGESL-RRAVYWLMGHLHGSTWSDVEVALPVV 236

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 222 MGGFALLMRDSWKLTALRLGEERAKSVGVNVQRLRLKILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEDQRFFLP 301
Cdd:PRK09535 237 VVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLP 316

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 835335030 302 LSFLIGAFLLSTASVLSKviVPGALFPIGIVTAIIGVPFFFWLIV 346
Cdd:PRK09535 317 TSALAGASFLVATDTVAR--SGPAEVPVGIVTAALGAPFFLYLLR 359
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 82-345 4.31e-39

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 139.23  E-value: 4.31e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  82 LMAIIVGGSLGVGGAEMQTLLNNPMASPYTLGMAAAAGFGAALMLYIGSLGMdnHYAVPLGAFLCCMLSACFLFALASMR 161
Cdd:cd06550    2 LAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLS--NYALGAFAFAGALAIALLVLLLASRG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 162 HITSGQLILAGIALLFLFQSLLSLVQFIASPELsQQILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLG 241
Cdd:cd06550   80 GLSPSKLILIGIVLSAFFSAGVILISLLSDDSL-QDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 242 EERAKSVGVNVQRLRLKILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVI 321
Cdd:cd06550  159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL 238

                        250       260
                 ....*....|....*....|....
gi 835335030 322 VPGALfPIGIVTAIIGVPFFFWLI 345
Cdd:cd06550  239 LPSEL-PVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 39-349 1.76e-82

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 252.68  E-value: 1.76e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  39 IMTGPSMLDASRVLNALLEFiglpfQVDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAEMQTLLNNPMASPYTLGMAAAA 118
Cdd:COG0609    2 LSLGAVPISLSDVLRALLGP-----DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 119 GFGAALMLYIGSLGMdnHYAVPLGAFLCCMLSACFLFALASM-RHITSGQLILAGIALLFLFQSLLSLVQFIASPELSQQ 197
Cdd:COG0609   77 ALGAVLAIVLGGGLS--ALGLPLAAFLGALLAALLVYLLARRgGGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 198 ILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLGEERAKSVGVNVQRLRLKILFIVAVMTATVTSFVGII 277
Cdd:COG0609  155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 835335030 278 GFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVIVPGALFPIGIVTAIIGVPFFFWLIVAKR 349
Cdd:COG0609  235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 30-346 1.01e-64

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 207.38  E-value: 1.01e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030   30 ILLASFVLDIMTGPSMLDASRVLNALLEFIglpfqvDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAEMQTLLNNPMASP 109
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGD------DSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADP 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  110 YTLGMAAAAGFGAALMLYIGSLGmdNHYAVPLGAFLCCMLSACFLFALASMR-HITSGQLILAGIALLFLFQSLLSLVQF 188
Cdd:pfam01032  75 SILGISSGAALGAVLAILLGGSL--SLFALPLAAFIGALLAALLVYFLSRGRgGASPLRLILAGIAVSALLSALTSLLLL 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  189 IASPELSQQILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLGEERAKSVGVNVQRLRLKILFIVAVMTA 268
Cdd:pfam01032 153 LLNPEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTA 232

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 835335030  269 TVTSFVGIIGFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVIVPGALFPIGIVTAIIGVPFFFWLIV 346
Cdd:pfam01032 233 ASVAVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLL 310
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 8-349 2.97e-50

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 170.42  E-value: 2.97e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030   8 QAIEQQRKSERRRwvvLCAFGTILLASFVLDIMTGPSMLDASRVLNALLEFIglpfqvdgstrviVTNLRLPIALMAIIV 87
Cdd:COG4139    2 QLPQRQRRRDRRW---LLLLLLLLLLLFVLSLCAGEVWIPPTQWLSEAWQLF-------------VWQLRLPRTLAAVLV 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  88 GGSLGVGGAEMQTLLNNPMASPYTLGMAAAAGFGAALMLYIGSlGMDNHYAVPLGAFLCCMLSACFLFALASmRHITSGQ 167
Cdd:COG4139   66 GASLAVSGAVMQALFENPLAEPGLLGISNGAGVGLVLVVLLGG-GLLPPWLLSLAAIAGALLVTLLLLAFAR-RRLSNAR 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 168 LILAGIALLFLFQSLLSLVQFIASPELSQQILFWLFGSLSKATWSNLTITAVVVmGGFALLMRDSWKLTALRLGEERAKS 247
Cdd:COG4139  144 LLLIGVALGIICSAIMTWAVYFSSSLDLRQLMYWMMGSFGGVDWRQLWLLLALL-PVLLWLCLQGKPLNLLLLGENQARQ 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 248 VGVNVQRLRLKILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVIVPGALF 327
Cdd:COG4139  223 LGLSVHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAALLLLADIIARLALSSAEL 302

                        330       340
                 ....*....|....*....|..
gi 835335030 328 PIGIVTAIIGVPFFFWLIVAKR 349
Cdd:COG4139  303 PIGVVTATLGAPVFIWLLLRRR 324
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 18-349 7.90e-50

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 169.92  E-value: 7.90e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  18 RRRWVVLCAFGTILLASFVLDIMTGPSMLDASRVLNALLefiGlpfQVDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAE 97
Cdd:COG4779   20 RRALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALL---G---EGDPGASFVVLELRLPRALAALLVGAALGLSGAI 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  98 MQTLLNNPMASP---------YTlgmaaaagFGAALMLYIGSLGmdnhYAVPLGAFLCCMLSACFLFALASMRHITSGQL 168
Cdd:COG4779   94 FQSLTRNPLASPdiigitagaSA--------GAVAAIVVLGGSG----LAVALGALAGGLATALLVYLLAWRGGVSGYRL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 169 ILAGIALLFLFQSLLSLVQFIASPELSQQILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLGEERAKSV 248
Cdd:COG4779  162 ILVGIGVSAMLTAVNSYLLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAAL 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 249 GVNVQRLRLKILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEDqRFFLPLSFLIGAFLLSTASVLSKVIVPGALFP 328
Cdd:COG4779  242 GVRVERTRLLLLLVAVALAAVATAAAGPIAFVALAAPQIARRLTRSP-GPPLLPSALVGALLLLAADLVAQHLLAPVQLP 320

                        330       340
                 ....*....|....*....|.
gi 835335030 329 IGIVTAIIGVPFFFWLIVAKR 349
Cdd:COG4779  321 VGVVTGALGGPYLLWLLIREN 341
btuC PRK09535
cobalamin ABC transporter permease BtuC;
63-346 4.68e-40

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 144.89  E-value: 4.68e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  63 FQVDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAEMQTLLNNPMASPYTLGMAAAAGFGAALMLYIGSLGMdnhYAVPLG 142
Cdd:PRK09535  81 FAVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAVP---FGLQAA 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 143 AFLCCMLSACFLFALASMR-HITSGQLILAGIALLFLFQSLLSLVQFIASPELsQQILFWLFGSLSKATWSNLTITAVVV 221
Cdd:PRK09535 158 AFAGALVAAFGVYAIATENgRTPVATLLLAGVAVQTFLGAVISYLLLHSGESL-RRAVYWLMGHLHGSTWSDVEVALPVV 236

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 222 MGGFALLMRDSWKLTALRLGEERAKSVGVNVQRLRLKILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEDQRFFLP 301
Cdd:PRK09535 237 VVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLP 316

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 835335030 302 LSFLIGAFLLSTASVLSKviVPGALFPIGIVTAIIGVPFFFWLIV 346
Cdd:PRK09535 317 TSALAGASFLVATDTVAR--SGPAEVPVGIVTAALGAPFFLYLLR 359
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
14-345 2.35e-39

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 147.68  E-value: 2.35e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  14 RKSERRRWVVLcAFGTILLASFVLDIMTGPSMLDASRVLNALLEFiglpfQVDGSTRVIVTNLRLPIALMAIIVGGSLGV 93
Cdd:PRK10577   5 MSRRRARLPAL-LLALLLLLALALTLTQLSAALPLSQWLQALWGP-----DADDLEQLLLHYSRLPRLAIALLVGAALGL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  94 GGAEMQTLLNNPMASPYTLGMAAAAGFGAAL-MLYIGSLGMDnhYAVPLgAFLCCMLSACFLFALASMRHITSGQLILAG 172
Cdd:PRK10577  79 AGALLQQVLRNPLASPTTLGVAAGAQLALVLaTLFAPALLAL--ASQLA-AFAGGLLAAALVFALAGGKRLSPLRLVLAG 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 173 IALLFLFQSLLSLVQfIASPELSQQILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLGEERAKSVGVNV 252
Cdd:PRK10577 156 MVVSLYLGALTTLLL-LFNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAV 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 253 QRLRLKILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVIVP--GALFPIG 330
Cdd:PRK10577 235 SLTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLLAGvgGELLPTG 314

                        330
                 ....*....|....*
gi 835335030 331 IVTAIIGVPFFFWLI 345
Cdd:PRK10577 315 AVTALIGAPLLLWLL 329
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 82-345 4.31e-39

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 139.23  E-value: 4.31e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  82 LMAIIVGGSLGVGGAEMQTLLNNPMASPYTLGMAAAAGFGAALMLYIGSLGMdnHYAVPLGAFLCCMLSACFLFALASMR 161
Cdd:cd06550    2 LAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLS--NYALGAFAFAGALAIALLVLLLASRG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 162 HITSGQLILAGIALLFLFQSLLSLVQFIASPELsQQILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLG 241
Cdd:cd06550   80 GLSPSKLILIGIVLSAFFSAGVILISLLSDDSL-QDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 242 EERAKSVGVNVQRLRLKILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVI 321
Cdd:cd06550  159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL 238

                        250       260
                 ....*....|....*....|....
gi 835335030 322 VPGALfPIGIVTAIIGVPFFFWLI 345
Cdd:cd06550  239 LPSEL-PVGPVTALLGAPYFLYLL 261
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
18-344 5.37e-39

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 146.52  E-value: 5.37e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  18 RRRWVVLCAFGTILLASFVLDIMTGPSMLDASrvlnallefiglpfQVDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAE 97
Cdd:PRK10577 352 RRVLAWLLALGLLLLLALVVALSFGRDAHGWN--------------WLSGQLLDALLPLRLPRLLAALLAGAMLAVAGTL 417

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  98 MQTLLNNPMASPYTLGMAAAAGFGAALMLYIgsLGMDNHYAVPLGAFLCCMLSACFLFALASMRHITSGQLILAGIALLF 177
Cdd:PRK10577 418 LQRLTRNPLASPEVLGISSGAGLGVVLALFL--VPGAGFGWLLAAALLGALAALALILLLARRGGFAPERLLLTGIALSA 495

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 178 LFQSLLSLVQFIASPElSQQILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLGEERAKSVGVNVQRLRL 257
Cdd:PRK10577 496 LFTALIQLLLASGDPR-AAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARALGLPVTRARL 574

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 258 KILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVIVPGALFPIGIVTAIIG 337
Cdd:PRK10577 575 ALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIG 654


                 ....*..
gi 835335030 338 VPFFFWL 344
Cdd:PRK10577 655 APYFLWL 661
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 6-349 1.91e-38

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 139.71  E-value: 1.91e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030   6 LLQAIEQQRKSERRRWVVLCAFgtiLLASFVLDIMTGPSMLdasrvlnallefigLPFQVDGST-RVIVTNLRLPIALMA 84
Cdd:PRK03784   3 MLTLARQQQRRNRRWLLGLSVL---LLLALLLSLCAGEQWI--------------SPGDWLSPRgELFVWQLRLPRTLAV 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  85 IIVGGSLGVGGAEMQTLLNNPMASPYTLGMAAAAGFGAALMLYIGSlGMDNHYAVPLGAFLCCMLSACFLFALASMRHIT 164
Cdd:PRK03784  66 LLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQ-GLLPPWALSLCAIAGALLITLILLRFARRHRLS 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 165 SGQLILAGIALLFLFQSLLS-LVQFIASPELsQQILFWLFGSLSKATWSNLTITAVVVMGGFALLMRdSWKLTALRLGEE 243
Cdd:PRK03784 145 TSRLLLAGVALGIICSALMTwAVYFSTSLDL-RQLMYWMMGGFGGVDWRQSWLMLALLPVLIWLCCQ-GRPLNMLALGEI 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 244 RAKSVGVNVQRLRLKILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVIVP 323
Cdd:PRK03784 223 SARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLLLLADIVARLALA 302

                        330       340
                 ....*....|....*....|....*.
gi 835335030 324 GALFPIGIVTAIIGVPFFFWLIVAKR 349
Cdd:PRK03784 303 SAELPIGVVTATLGAPVFIWLLLRSH 328
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
61-344 9.73e-36

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 132.13  E-value: 9.73e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  61 LPFQVDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAEMQTLLNNPMASPYTLGMAAAAGFGAALMLYIGSLGMDNhYAVP 140
Cdd:PRK11228  35 LPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTSALSPTPFAG-YSLA 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 141 LGAFLCCMLSACFLFALASMRHITS--GQLILAGIALLFLFQSLLSLVQFIASPElSQQILFWLFGSLSKATWSNLTIT- 217
Cdd:PRK11228 114 FIAACGGGLSWLLVMTAGGGWRHTHdrNRLILAGIALSALCMALTRITLLLAEDH-AYGIFYWLAGGVSHARWQEVWQLl 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 218 -AVVVMGGFALLMRDswKLTALRLGEERAKSVGVNVQRLRLKILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEDQ 296
Cdd:PRK11228 193 pFVVTAVPVVLLLAN--QLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIGYDQ 270

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 835335030 297 RFFLPLSFLIGAFLLSTASVLSKVIVPGALFPIGIVTAIIGVPFFFWL 344
Cdd:PRK11228 271 RNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWL 318
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
31-349 6.18e-34

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 127.08  E-value: 6.18e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  31 LLASFVLDIMTGPSMLDASRVLNAllefiglpFQVDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAEMQTLLNNPMASPY 110
Cdd:PRK09777  13 LAGCALLSLRMGVIPLPWRALLTD--------WQAGDEHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 111 TLGMA-AAAGFGAALMLYIGSLGMdnhYAVPLGAFLCCMLSACFLFALASMRhiTSGQLILAGIALLFLFQSLLSLVqFI 189
Cdd:PRK09777  85 ILGVNhAASLASVGALLLFPSLPV---MWLPLLAFIGGMAGLILLKMLAGTH--QPMKLALTGVALSALWASLTDYL-ML 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 190 ASPELSQQILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLGEERAKSVGVNVQRLRLKILFIVAVMTAT 269
Cdd:PRK09777 159 SRPQDINNALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTAT 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 270 VTSFVGIIGFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVIVPGALFPIGIVTAIIGVPFFFWLIVAKR 349
Cdd:PRK09777 239 GVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLLVRMR 318
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
19-350 2.41e-30

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 117.89  E-value: 2.41e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  19 RRWVVLCAFGTILLASFVLDIMTGPSMLDASRVLNALLEfiglpfQVDGSTRVIVTNLRLPIALMAIIVGGSLGVGGAEM 98
Cdd:PRK10441   8 TRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEALSG------TCQSADCTIVLDARLPRTLAGLLAGGALGLAGALM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  99 QTLLNNPMASPYTLGMAAAAGFGaaLMLYIGSLGMDNHYAVPLGAFLCCMLSACFLFALASM--RHITSGQLILAGIALL 176
Cdd:PRK10441  82 QTLTRNPLADPGLLGVNAGASFA--IVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQggGQLSPVRLTLAGVALA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 177 FLFQSLLSLVQFIaSPELSQQILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLGEERAKSVGVNVQRLR 256
Cdd:PRK10441 160 AVLEGLTSGIALL-NPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQ 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 257 LKILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEDQRFFLPLSFLIGAFLLSTASVLSKVIVPGALfPIGIVTAII 336
Cdd:PRK10441 239 LIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRLLVPGEL-RVSVVSAFI 317

                        330
                 ....*....|....
gi 835335030 337 GVPFFFWLIVAKRG 350
Cdd:PRK10441 318 GAPVLIFLVRRKTR 331
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
14-346 2.68e-28

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 112.50  E-value: 2.68e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  14 RKSERRRWVVLCAFGTILLASfVLDIMTGPSMLDASRVLNALLEfiglpfQVDGSTRVIVTNLRLPIALMAIIVGGSLGV 93
Cdd:PRK10440   3 YVSRRLLITCLLLLAACVAAG-LWGLRSGAVTLETSQVFAALMG------DAPRSMTMVVTEWRLPRVLMALLIGAALGV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030  94 GGAEMQTLLNNPMASPYTLGMAAAAGFGAALMLyigSLGMDNHYAVPLGAFLCCMLSACFLFALASMRHITSGQLILAGI 173
Cdd:PRK10440  76 SGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAM---VLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 174 ALLFLFQSLLSLVQFIASPELSQQILFWLFGSLSKATWSNLTITAVVVMGGFALLMRDSWKLTALRLGEERAKSVGVNVQ 253
Cdd:PRK10440 153 GVRAMLVAFNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVE 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 835335030 254 RLRLKILFIVAVMTATVTSFVGIIGFIGIVAPNIAKILVGEdQRFFLPLSFLIGAFLLSTASVLSKVIVPGALFPIGIVT 333
Cdd:PRK10440 233 RSRLLLMLVAVVLTAAATALAGPISFIALVAPHIARRLSGT-ARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVT 311

                        330
                 ....*....|...
gi 835335030 334 AIIGVPFFFWLIV 346
Cdd:PRK10440 312 VSLGGIYLIVLLI 324
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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