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Conserved domains on  [gi|850376579|ref|WP_048030981|]
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MULTISPECIES: type II toxin-antitoxin system Phd/YefM family antitoxin [Enterobacteriaceae]

Protein Classification

type II toxin-antitoxin system Phd/YefM family antitoxin( domain architecture ID 10005482)

type II toxin-antitoxin (TA) system Phd/YefM family antitoxin is the antitoxin component of a TA module that binds to its cognate toxin and neutralizes its mRNA interferase activity; similar to Escherichia virus P1 antitoxin phd (prevent-host-death)

Gene Ontology:  GO:0003677|GO:0097351|GO:0006355|GO:0045927|GO:0110001
PubMed:  9829946|18757857|27159580

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
StbD COG2161
Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense ...
 9-50 4.87e-08

Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms];


:

Pssm-ID: 441764  Cd Length: 83  Bit Score: 45.55  E-value: 4.87e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 850376579  9 TAASITELKRDPMGTFHAG--DGAPVAILNRNEPAFYCVPPALY 50
Cdd:COG2161   2 TTISYSEARKNLASLLDQVveDHEPVIITRRNGPAAVLISAEDY 45
 
Name Accession Description Interval E-value
StbD COG2161
Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense ...
 9-50 4.87e-08

Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms];


Pssm-ID: 441764  Cd Length: 83  Bit Score: 45.55  E-value: 4.87e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 850376579  9 TAASITELKRDPMGTFHAG--DGAPVAILNRNEPAFYCVPPALY 50
Cdd:COG2161   2 TTISYSEARKNLASLLDQVveDHEPVIITRRNGPAAVLISAEDY 45
PRK02854 PRK02854
primosomal protein DnaT;
1-52 4.78e-06

primosomal protein DnaT;


Pssm-ID: 179484  Cd Length: 179  Bit Score: 42.10  E-value: 4.78e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 850376579   1 MAFQVLTTTAASITELKRDPMGTFHAGDGAPVAILNRNEPAFYCVPPALYAQ 52
Cdd:PRK02854   1 MSSRILTSDVIGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAE 52
 
Name Accession Description Interval E-value
StbD COG2161
Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense ...
 9-50 4.87e-08

Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms];


Pssm-ID: 441764  Cd Length: 83  Bit Score: 45.55  E-value: 4.87e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 850376579  9 TAASITELKRDPMGTFHAG--DGAPVAILNRNEPAFYCVPPALY 50
Cdd:COG2161   2 TTISYSEARKNLASLLDQVveDHEPVIITRRNGPAAVLISAEDY 45
PRK02854 PRK02854
primosomal protein DnaT;
1-52 4.78e-06

primosomal protein DnaT;


Pssm-ID: 179484  Cd Length: 179  Bit Score: 42.10  E-value: 4.78e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 850376579   1 MAFQVLTTTAASITELKRDPMGTFHAGDGAPVAILNRNEPAFYCVPPALYAQ 52
Cdd:PRK02854   1 MSSRILTSDVIGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAE 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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