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Conserved domains on  [gi|872563061|ref|WP_048530629|]
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MULTISPECIES: sporulation integral membrane protein YlbJ [Bacillus]

Protein Classification

sporulation integral membrane protein YlbJ( domain architecture ID 10798643)

sporulation integral membrane protein YlbJ is required for spore cortex formation

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
spore_ylbJ TIGR02871
sporulation integral membrane protein YlbJ; Members of this protein family are found ...
10-391 1.49e-117

sporulation integral membrane protein YlbJ; Members of this protein family are found exclusively in Firmicutes (low-GC Gram-positive bacterial) and are known from studies in Bacillus subtilis to be part of the sigma-E regulon. Mutation leads to a sporulation defect, confirming that members of this protein family, YlbJ, are sporulation proteins. This protein appears to be universal among endospore-forming bacteria, but is encoded by a pair ORFs distant from eash other in Symbiobacterium thermophilum IAM14863. [Cellular processes, Sporulation and germination]


:

Pssm-ID: 274333  Cd Length: 362  Bit Score: 346.64  E-value: 1.49e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061   10 LTISTLFLTFSLVLHPQAALQASIRGLNIWWEVVFPSLLPFFIIAELLISIGVVKFIGVILEPLMRPLFRVPGIGGFVWA 89
Cdd:TIGR02871   4 LASLLTLLILSFILNPKASIEASKSGAKLWFYSVFPSLFPFFIISELLINLGGVHFYGKLLEPILRPPFRVPGVGSFALV 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061   90 MGMASGFPAGAKLSARLRKSNQLTQIEAERLVSFTNSSNPLFIFGAVSIGFFNNPKLGIVLAAAHYLSNFFVGLLMRFYG 169
Cdd:TIGR02871  84 MGFLSGYPLGAKYSADLYEEKLITFEEAERLLNFANNSGPLFIIGAVGTSMLNNPTLGYILLISHYLSCITMGLILRFYK 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061  170 NNNIsthdKHTTKKRPfqnpfsILHETRMQEKRPIGKLLGDAIVSSIQTLLMIGGFIILFSVLNKMITVFHITaalSFIM 249
Cdd:TIGR02871 164 RRKR----KILSKKKK------TFHIIRLKSKFPIGKTLKEAIENAVKTILLVGGFVILFSVVISLLKNSFIF---KLIL 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061  250 QHILSFFQLTTEFSIPILSGIFEMTLGSQMISQINEtPLLQQAMVTSFILAFSGLSIQAQVASILAETDIRFKPYFFARI 329
Cdd:TIGR02871 231 KPLLSLFNLPEQLIIGFFLGILEITNGSKMISESSI-SLLQKVILISFLLSFGGISIIAQVASFISKTKISYKPYFIAKL 309
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 872563061  330 IQSILAPIFTFIFWKPFYEKVSsfSPMQKDIPVFFSNSSSIpheiwtsFIHYGPIFTLVCLY 391
Cdd:TIGR02871 310 LQGVIASIISYLLYKILYLKNA--IGTFTAINSAILNPSNL-------LQIIGFLLLLFLLF 362
 
Name Accession Description Interval E-value
spore_ylbJ TIGR02871
sporulation integral membrane protein YlbJ; Members of this protein family are found ...
10-391 1.49e-117

sporulation integral membrane protein YlbJ; Members of this protein family are found exclusively in Firmicutes (low-GC Gram-positive bacterial) and are known from studies in Bacillus subtilis to be part of the sigma-E regulon. Mutation leads to a sporulation defect, confirming that members of this protein family, YlbJ, are sporulation proteins. This protein appears to be universal among endospore-forming bacteria, but is encoded by a pair ORFs distant from eash other in Symbiobacterium thermophilum IAM14863. [Cellular processes, Sporulation and germination]


Pssm-ID: 274333  Cd Length: 362  Bit Score: 346.64  E-value: 1.49e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061   10 LTISTLFLTFSLVLHPQAALQASIRGLNIWWEVVFPSLLPFFIIAELLISIGVVKFIGVILEPLMRPLFRVPGIGGFVWA 89
Cdd:TIGR02871   4 LASLLTLLILSFILNPKASIEASKSGAKLWFYSVFPSLFPFFIISELLINLGGVHFYGKLLEPILRPPFRVPGVGSFALV 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061   90 MGMASGFPAGAKLSARLRKSNQLTQIEAERLVSFTNSSNPLFIFGAVSIGFFNNPKLGIVLAAAHYLSNFFVGLLMRFYG 169
Cdd:TIGR02871  84 MGFLSGYPLGAKYSADLYEEKLITFEEAERLLNFANNSGPLFIIGAVGTSMLNNPTLGYILLISHYLSCITMGLILRFYK 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061  170 NNNIsthdKHTTKKRPfqnpfsILHETRMQEKRPIGKLLGDAIVSSIQTLLMIGGFIILFSVLNKMITVFHITaalSFIM 249
Cdd:TIGR02871 164 RRKR----KILSKKKK------TFHIIRLKSKFPIGKTLKEAIENAVKTILLVGGFVILFSVVISLLKNSFIF---KLIL 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061  250 QHILSFFQLTTEFSIPILSGIFEMTLGSQMISQINEtPLLQQAMVTSFILAFSGLSIQAQVASILAETDIRFKPYFFARI 329
Cdd:TIGR02871 231 KPLLSLFNLPEQLIIGFFLGILEITNGSKMISESSI-SLLQKVILISFLLSFGGISIIAQVASFISKTKISYKPYFIAKL 309
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 872563061  330 IQSILAPIFTFIFWKPFYEKVSsfSPMQKDIPVFFSNSSSIpheiwtsFIHYGPIFTLVCLY 391
Cdd:TIGR02871 310 LQGVIASIISYLLYKILYLKNA--IGTFTAINSAILNPSNL-------LQIIGFLLLLFLLF 362
SpoVV COG3314
Spore dipicolinate transporter SpoVV/YjiH/YlbJ, contains nucleoside recognition GATE domain ...
7-347 1.11e-89

Spore dipicolinate transporter SpoVV/YjiH/YlbJ, contains nucleoside recognition GATE domain [Cell cycle control, cell division, chromosome partitioning, Amino acid transport and metabolism];


Pssm-ID: 442543  Cd Length: 434  Bit Score: 277.90  E-value: 1.11e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061   7 TAFLTISTLFLTFSLVLH-PQAALQASIRGLNIWweVVFPSLLPFFIIA----ELLISIGVVKFIGVILEPLMRPLFRVP 81
Cdd:COG3314   84 SLLRVLGAVFAVMVLFKYgPEAIFSAATGGLLLW--VLLPSLLPFFIIAalflPLLLGFGLVEFIGVLLEPIMRPLFKLP 161
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061  82 GIGGFVWAMGMASGFPAGAKLSARLRKSNQLTQIEAERLVSFTNSSNPLFIFGAVSIGFFNNPklgivlAAAHYLSNFFV 161
Cdd:COG3314  162 GRSAFDAAASWVGGYPVGALLTSRLYEEGYYTKREAARIATFFSTVSPLFMIVVAAVGGLMDP------FLAHYLTVLLV 235
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061 162 GLLMRFYG-------------NNNISTHDKHTTKKRPFQNPFSILHETRmQEKRPIGKLLGDAIVSSIQTLLMIGGFIIL 228
Cdd:COG3314  236 GFIVAFITpripplsrkpdtyYEGRKPQPEEPEGGNLFKRALKEALEAA-EKARSLGKLLGDAVKNSLNMLLGIGPFIMA 314
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061 229 FSVLNKMITVF-HITAALSFIMQHILSFFQL--TTEFSIPILSGIFEMTLGSQMISQIneTPLLQQAMVTsfILAFSGLS 305
Cdd:COG3314  315 FGVLALILAEYtPIFDWLGYPFYPLLELLGLpeAAEAAPAIISGFAEMFLPAILASEI--ASLLTRFVIA--ILSVSGLI 390
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 872563061 306 IQAQVASILAETDI--RFKPYFFARIIQSILAPIFTFIFWKPFY 347
Cdd:COG3314  391 YFSQVGSLLLGTDIplRFKDLFIIFLLRTILSLPITALIAHLLF 434
Gate pfam07670
Nucleoside recognition; This region in the nucleoside transporter proteins are responsible for ...
42-133 1.16e-04

Nucleoside recognition; This region in the nucleoside transporter proteins are responsible for determining nucleoside specificity in the human CNT1 and CNT2 proteins. In the FeoB proteins, which are believed to be Fe2+ transporters, it includes the membrane pore region, so the function of this region is likely to be more general than just nucleoside specificity. This family may represent the pore and gate, with a wide potential range of specificity. Hence its name 'Gate'.


Pssm-ID: 429586 [Multi-domain]  Cd Length: 101  Bit Score: 41.09  E-value: 1.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061   42 VVFPSLLPFFIIAELLISIGVVKFIGVILEPLMRPL--FRVPGIGGFVWAMGMASGFPAGAKLSARLRKSNQLTQIEAER 119
Cdd:pfam07670   3 KVLPIILFFSVLISILEYSGLLDRIGKLLGPLMRPLglFPLPGKAAIALLLGFGAKEVGVPLLATPYGIDTPRERLAALL 82
                          90
                  ....*....|....
gi 872563061  120 LVSFTNSSNPLFIF 133
Cdd:pfam07670  83 FTSFSTPCGATLPV 96
 
Name Accession Description Interval E-value
spore_ylbJ TIGR02871
sporulation integral membrane protein YlbJ; Members of this protein family are found ...
10-391 1.49e-117

sporulation integral membrane protein YlbJ; Members of this protein family are found exclusively in Firmicutes (low-GC Gram-positive bacterial) and are known from studies in Bacillus subtilis to be part of the sigma-E regulon. Mutation leads to a sporulation defect, confirming that members of this protein family, YlbJ, are sporulation proteins. This protein appears to be universal among endospore-forming bacteria, but is encoded by a pair ORFs distant from eash other in Symbiobacterium thermophilum IAM14863. [Cellular processes, Sporulation and germination]


Pssm-ID: 274333  Cd Length: 362  Bit Score: 346.64  E-value: 1.49e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061   10 LTISTLFLTFSLVLHPQAALQASIRGLNIWWEVVFPSLLPFFIIAELLISIGVVKFIGVILEPLMRPLFRVPGIGGFVWA 89
Cdd:TIGR02871   4 LASLLTLLILSFILNPKASIEASKSGAKLWFYSVFPSLFPFFIISELLINLGGVHFYGKLLEPILRPPFRVPGVGSFALV 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061   90 MGMASGFPAGAKLSARLRKSNQLTQIEAERLVSFTNSSNPLFIFGAVSIGFFNNPKLGIVLAAAHYLSNFFVGLLMRFYG 169
Cdd:TIGR02871  84 MGFLSGYPLGAKYSADLYEEKLITFEEAERLLNFANNSGPLFIIGAVGTSMLNNPTLGYILLISHYLSCITMGLILRFYK 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061  170 NNNIsthdKHTTKKRPfqnpfsILHETRMQEKRPIGKLLGDAIVSSIQTLLMIGGFIILFSVLNKMITVFHITaalSFIM 249
Cdd:TIGR02871 164 RRKR----KILSKKKK------TFHIIRLKSKFPIGKTLKEAIENAVKTILLVGGFVILFSVVISLLKNSFIF---KLIL 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061  250 QHILSFFQLTTEFSIPILSGIFEMTLGSQMISQINEtPLLQQAMVTSFILAFSGLSIQAQVASILAETDIRFKPYFFARI 329
Cdd:TIGR02871 231 KPLLSLFNLPEQLIIGFFLGILEITNGSKMISESSI-SLLQKVILISFLLSFGGISIIAQVASFISKTKISYKPYFIAKL 309
                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 872563061  330 IQSILAPIFTFIFWKPFYEKVSsfSPMQKDIPVFFSNSSSIpheiwtsFIHYGPIFTLVCLY 391
Cdd:TIGR02871 310 LQGVIASIISYLLYKILYLKNA--IGTFTAINSAILNPSNL-------LQIIGFLLLLFLLF 362
SpoVV COG3314
Spore dipicolinate transporter SpoVV/YjiH/YlbJ, contains nucleoside recognition GATE domain ...
7-347 1.11e-89

Spore dipicolinate transporter SpoVV/YjiH/YlbJ, contains nucleoside recognition GATE domain [Cell cycle control, cell division, chromosome partitioning, Amino acid transport and metabolism];


Pssm-ID: 442543  Cd Length: 434  Bit Score: 277.90  E-value: 1.11e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061   7 TAFLTISTLFLTFSLVLH-PQAALQASIRGLNIWweVVFPSLLPFFIIA----ELLISIGVVKFIGVILEPLMRPLFRVP 81
Cdd:COG3314   84 SLLRVLGAVFAVMVLFKYgPEAIFSAATGGLLLW--VLLPSLLPFFIIAalflPLLLGFGLVEFIGVLLEPIMRPLFKLP 161
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061  82 GIGGFVWAMGMASGFPAGAKLSARLRKSNQLTQIEAERLVSFTNSSNPLFIFGAVSIGFFNNPklgivlAAAHYLSNFFV 161
Cdd:COG3314  162 GRSAFDAAASWVGGYPVGALLTSRLYEEGYYTKREAARIATFFSTVSPLFMIVVAAVGGLMDP------FLAHYLTVLLV 235
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061 162 GLLMRFYG-------------NNNISTHDKHTTKKRPFQNPFSILHETRmQEKRPIGKLLGDAIVSSIQTLLMIGGFIIL 228
Cdd:COG3314  236 GFIVAFITpripplsrkpdtyYEGRKPQPEEPEGGNLFKRALKEALEAA-EKARSLGKLLGDAVKNSLNMLLGIGPFIMA 314
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061 229 FSVLNKMITVF-HITAALSFIMQHILSFFQL--TTEFSIPILSGIFEMTLGSQMISQIneTPLLQQAMVTsfILAFSGLS 305
Cdd:COG3314  315 FGVLALILAEYtPIFDWLGYPFYPLLELLGLpeAAEAAPAIISGFAEMFLPAILASEI--ASLLTRFVIA--ILSVSGLI 390
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 872563061 306 IQAQVASILAETDI--RFKPYFFARIIQSILAPIFTFIFWKPFY 347
Cdd:COG3314  391 YFSQVGSLLLGTDIplRFKDLFIIFLLRTILSLPITALIAHLLF 434
Gate pfam07670
Nucleoside recognition; This region in the nucleoside transporter proteins are responsible for ...
42-133 1.16e-04

Nucleoside recognition; This region in the nucleoside transporter proteins are responsible for determining nucleoside specificity in the human CNT1 and CNT2 proteins. In the FeoB proteins, which are believed to be Fe2+ transporters, it includes the membrane pore region, so the function of this region is likely to be more general than just nucleoside specificity. This family may represent the pore and gate, with a wide potential range of specificity. Hence its name 'Gate'.


Pssm-ID: 429586 [Multi-domain]  Cd Length: 101  Bit Score: 41.09  E-value: 1.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061   42 VVFPSLLPFFIIAELLISIGVVKFIGVILEPLMRPL--FRVPGIGGFVWAMGMASGFPAGAKLSARLRKSNQLTQIEAER 119
Cdd:pfam07670   3 KVLPIILFFSVLISILEYSGLLDRIGKLLGPLMRPLglFPLPGKAAIALLLGFGAKEVGVPLLATPYGIDTPRERLAALL 82
                          90
                  ....*....|....
gi 872563061  120 LVSFTNSSNPLFIF 133
Cdd:pfam07670  83 FTSFSTPCGATLPV 96
Gate pfam07670
Nucleoside recognition; This region in the nucleoside transporter proteins are responsible for ...
219-317 1.63e-04

Nucleoside recognition; This region in the nucleoside transporter proteins are responsible for determining nucleoside specificity in the human CNT1 and CNT2 proteins. In the FeoB proteins, which are believed to be Fe2+ transporters, it includes the membrane pore region, so the function of this region is likely to be more general than just nucleoside specificity. This family may represent the pore and gate, with a wide potential range of specificity. Hence its name 'Gate'.


Pssm-ID: 429586 [Multi-domain]  Cd Length: 101  Bit Score: 40.70  E-value: 1.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061  219 LLMIGGFIILFSVLNKMITVFHITAALSFIMQHILS---FFQLTTEFSIPILSGIFEMTLGSQMISQINETPLLQQAMVT 295
Cdd:pfam07670   1 LLKVLPIILFFSVLISILEYSGLLDRIGKLLGPLMRplgLFPLPGKAAIALLLGFGAKEVGVPLLATPYGIDTPRERLAA 80
                          90       100
                  ....*....|....*....|..
gi 872563061  296 SFILAFSGLSIqAQVASILAET 317
Cdd:pfam07670  81 LLFTSFSTPCG-ATLPVYAGEL 101
2A067 TIGR00921
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ...
190-266 4.37e-03

The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 273340 [Multi-domain]  Cd Length: 719  Bit Score: 39.44  E-value: 4.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563061  190 FSILHETRMQEKRPIGKLLGDAIVSSIQ--------TLLM-IGGFIILFSVLNKMITVFHITAALSFIMQHILS-FFQLT 259
Cdd:TIGR00921 263 YGIQTLNRYEEERDIGRAKGEAIVTAVRrtgravliALLTtSAGFAALALSEFPMVSEFGLGLVAGLITAYLLTlLVLPA 342

                  ....*..
gi 872563061  260 TEFSIPI 266
Cdd:TIGR00921 343 LLQSIDI 349
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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