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Conserved domains on  [gi|872563064|ref|WP_048530632|]
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MULTISPECIES: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD [Bacillus]

Protein Classification

RsmD family RNA methyltransferase( domain architecture ID 10002368)

RsmD family RNA methyltransferase similar to 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD, which specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle

CATH:  3.40.50.150
EC:  2.1.1.-
Gene Ontology:  GO:0003676|GO:0031167|GO:0008168

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
RsmD COG0742
16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 1-185 2.18e-82

16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA G966 N2-methylase RsmD is part of the Pathway/BioSystem: 16S rRNA modification


:

Pssm-ID: 440505 [Multi-domain]  Cd Length: 183  Bit Score: 241.91  E-value: 2.18e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   1 MRVVSGKCKGHPLKAVPGNTTRPTTDKVKESIFNMIGPYFDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVI 80
Cdd:COG0742    1 MRIIGGKARGRKLKVPKGPGTRPTTDRVREALFNILGPDIEGARVLDLFAGSGALGLEALSRGAASVVFVEKDRKAAAVI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  81 HQNLESCRIQEQAEVYRNDAERAVKALikREISFDLILIDPPYKDQKIVSLISVMDQHGLLHRDGLIMSEHGNDVVLPES 160
Cdd:COG0742   81 RKNLEKLGLEDRARVIRGDALRFLKRL--AGEPFDLVFLDPPYAKGLLEKALELLAENGLLAPGGLIVVEHSKREELPEL 158

                        170       180
                 ....*....|....*....|....*
gi 872563064 161 IGRLVKVRAENYGITAISIYKYEGE 185
Cdd:COG0742  159 PAGLELLKERKYGDTRLSFYRREEE 183
 
Name Accession Description Interval E-value
RsmD COG0742
16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 1-185 2.18e-82

16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA G966 N2-methylase RsmD is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440505 [Multi-domain]  Cd Length: 183  Bit Score: 241.91  E-value: 2.18e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   1 MRVVSGKCKGHPLKAVPGNTTRPTTDKVKESIFNMIGPYFDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVI 80
Cdd:COG0742    1 MRIIGGKARGRKLKVPKGPGTRPTTDRVREALFNILGPDIEGARVLDLFAGSGALGLEALSRGAASVVFVEKDRKAAAVI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  81 HQNLESCRIQEQAEVYRNDAERAVKALikREISFDLILIDPPYKDQKIVSLISVMDQHGLLHRDGLIMSEHGNDVVLPES 160
Cdd:COG0742   81 RKNLEKLGLEDRARVIRGDALRFLKRL--AGEPFDLVFLDPPYAKGLLEKALELLAENGLLAPGGLIVVEHSKREELPEL 158

                        170       180
                 ....*....|....*....|....*
gi 872563064 161 IGRLVKVRAENYGITAISIYKYEGE 185
Cdd:COG0742  159 PAGLELLKERKYGDTRLSFYRREEE 183
Cons_hypoth95 pfam03602
Conserved hypothetical protein 95;
1-181 5.73e-68

Conserved hypothetical protein 95;


Pssm-ID: 427391 [Multi-domain]  Cd Length: 179  Bit Score: 205.17  E-value: 5.73e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064    1 MRVVSGKCKGHPLKAVPGNTTRPTTDKVKESIFNMIGPYFDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVI 80
Cdd:pfam03602   1 MRIIGGKARGRKLKVPPGPGTRPTTDRVREALFNWLAPYIEGARVLDLFAGSGALGLEALSRGAKRVTLVEKDKRAVQIL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   81 HQNLESCRIQEQaeVYRNDAERAVKALIKREISFDLILIDPPYKDQKIVSLISVMDQHGLLHRDGLIMSEHGNDVVLPES 160
Cdd:pfam03602  81 KENLQLLGLPGA--VLVMDALLALLRLAGKGPVFDIVFLDPPYAKGLIEEVLDLLAEKGWLKPNALIYVETEKRGELPEQ 158

                         170       180
                  ....*....|....*....|.
gi 872563064  161 IGRLVKVRAENYGITAISIYK 181
Cdd:pfam03602 159 PGNLELVREKKYGQTTLAFYQ 179
TIGR00095 TIGR00095
16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; This model represents a family of ...
 2-181 4.45e-58

16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; This model represents a family of uncharacterized bacterial proteins. Members are present in nearly every complete bacterial genome, always in a single copy. PSI-BLAST analysis shows homology to several families of SAM-dependent methyltransferases, including ribosomal RNA adenine dimethylases. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 188022 [Multi-domain]  Cd Length: 190  Bit Score: 180.30  E-value: 4.45e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064    2 RVVSGKCKGHPLKAVPGNTTRPTTDKVKESIFNMIGPYFDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVIH 81
Cdd:TIGR00095  11 RIIGGQYRGRKLKVPPGPSTRPTTDRVRESLFNILRPDIVGAHFLDLFAGSGALGLEALSRGAASAVFVEQDRKVAQTLK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   82 QNLESCRIQEQAEVYRNDAERAVKALIKREISFDLILIDPPYKDQKIVSLISVMDQHGLLHRDGLIMSEHGNDVVLPESI 161
Cdd:TIGR00095  91 ENLSTLKKSGEQATVLNDAVRALLFLAKKQTPFDIIYLDPPFNRGLLEALLELLGENKWLNPKGLIVVEYDRENELPTVP 170

                         170       180
                  ....*....|....*....|
gi 872563064  162 GRLVKVRAENYGITAISIYK 181
Cdd:TIGR00095 171 ETWSLLRQKVYGQSALRLYQ 190
rsmD PRK10909
16S rRNA m(2)G966-methyltransferase; Provisional
 1-150 1.21e-21

16S rRNA m(2)G966-methyltransferase; Provisional


Pssm-ID: 236793  Cd Length: 199  Bit Score: 87.08  E-value: 1.21e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   1 MRVVSGKCKGH--PLKAVPGntTRPTTDKVKESIFNMIGPYFDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIK 78
Cdd:PRK10909  13 IRIIGGQWRGRklPVPDSPG--LRPTTDRVRETLFNWLAPVIVDARCLDCFAGSGALGLEALSRYAAGATLLEMDRAVAQ 90

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 872563064  79 VIHQNLESCRiQEQAEVYRNDaerAVKALIKREISFDLILIDPPYKDQKIVSLISVMDQHGLLHRDGLIMSE 150
Cdd:PRK10909  91 QLIKNLATLK-AGNARVVNTN---ALSFLAQPGTPHNVVFVDPPFRKGLLEETINLLEDNGWLADEALIYVE 158
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 46-123 4.30e-05

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 40.88  E-value: 4.30e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 872563064  46 LDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVIHQNLEsCRIQEQAEVYRNDAEravKALIKREISFDLILIDPPY 123
Cdd:cd02440    3 LDLGCGTGALALALASGPGARVTGVDISPVALELARKAAA-ALLADNVEVLKGDAE---ELPPEADESFDVIISDPPL 76
 
Name Accession Description Interval E-value
RsmD COG0742
16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 1-185 2.18e-82

16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA G966 N2-methylase RsmD is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440505 [Multi-domain]  Cd Length: 183  Bit Score: 241.91  E-value: 2.18e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   1 MRVVSGKCKGHPLKAVPGNTTRPTTDKVKESIFNMIGPYFDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVI 80
Cdd:COG0742    1 MRIIGGKARGRKLKVPKGPGTRPTTDRVREALFNILGPDIEGARVLDLFAGSGALGLEALSRGAASVVFVEKDRKAAAVI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  81 HQNLESCRIQEQAEVYRNDAERAVKALikREISFDLILIDPPYKDQKIVSLISVMDQHGLLHRDGLIMSEHGNDVVLPES 160
Cdd:COG0742   81 RKNLEKLGLEDRARVIRGDALRFLKRL--AGEPFDLVFLDPPYAKGLLEKALELLAENGLLAPGGLIVVEHSKREELPEL 158

                        170       180
                 ....*....|....*....|....*
gi 872563064 161 IGRLVKVRAENYGITAISIYKYEGE 185
Cdd:COG0742  159 PAGLELLKERKYGDTRLSFYRREEE 183
Cons_hypoth95 pfam03602
Conserved hypothetical protein 95;
1-181 5.73e-68

Conserved hypothetical protein 95;


Pssm-ID: 427391 [Multi-domain]  Cd Length: 179  Bit Score: 205.17  E-value: 5.73e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064    1 MRVVSGKCKGHPLKAVPGNTTRPTTDKVKESIFNMIGPYFDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVI 80
Cdd:pfam03602   1 MRIIGGKARGRKLKVPPGPGTRPTTDRVREALFNWLAPYIEGARVLDLFAGSGALGLEALSRGAKRVTLVEKDKRAVQIL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   81 HQNLESCRIQEQaeVYRNDAERAVKALIKREISFDLILIDPPYKDQKIVSLISVMDQHGLLHRDGLIMSEHGNDVVLPES 160
Cdd:pfam03602  81 KENLQLLGLPGA--VLVMDALLALLRLAGKGPVFDIVFLDPPYAKGLIEEVLDLLAEKGWLKPNALIYVETEKRGELPEQ 158

                         170       180
                  ....*....|....*....|.
gi 872563064  161 IGRLVKVRAENYGITAISIYK 181
Cdd:pfam03602 159 PGNLELVREKKYGQTTLAFYQ 179
TIGR00095 TIGR00095
16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; This model represents a family of ...
 2-181 4.45e-58

16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; This model represents a family of uncharacterized bacterial proteins. Members are present in nearly every complete bacterial genome, always in a single copy. PSI-BLAST analysis shows homology to several families of SAM-dependent methyltransferases, including ribosomal RNA adenine dimethylases. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 188022 [Multi-domain]  Cd Length: 190  Bit Score: 180.30  E-value: 4.45e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064    2 RVVSGKCKGHPLKAVPGNTTRPTTDKVKESIFNMIGPYFDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVIH 81
Cdd:TIGR00095  11 RIIGGQYRGRKLKVPPGPSTRPTTDRVRESLFNILRPDIVGAHFLDLFAGSGALGLEALSRGAASAVFVEQDRKVAQTLK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   82 QNLESCRIQEQAEVYRNDAERAVKALIKREISFDLILIDPPYKDQKIVSLISVMDQHGLLHRDGLIMSEHGNDVVLPESI 161
Cdd:TIGR00095  91 ENLSTLKKSGEQATVLNDAVRALLFLAKKQTPFDIIYLDPPFNRGLLEALLELLGENKWLNPKGLIVVEYDRENELPTVP 170

                         170       180
                  ....*....|....*....|
gi 872563064  162 GRLVKVRAENYGITAISIYK 181
Cdd:TIGR00095 171 ETWSLLRQKVYGQSALRLYQ 190
rsmD PRK10909
16S rRNA m(2)G966-methyltransferase; Provisional
 1-150 1.21e-21

16S rRNA m(2)G966-methyltransferase; Provisional


Pssm-ID: 236793  Cd Length: 199  Bit Score: 87.08  E-value: 1.21e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   1 MRVVSGKCKGH--PLKAVPGntTRPTTDKVKESIFNMIGPYFDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIK 78
Cdd:PRK10909  13 IRIIGGQWRGRklPVPDSPG--LRPTTDRVRETLFNWLAPVIVDARCLDCFAGSGALGLEALSRYAAGATLLEMDRAVAQ 90

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 872563064  79 VIHQNLESCRiQEQAEVYRNDaerAVKALIKREISFDLILIDPPYKDQKIVSLISVMDQHGLLHRDGLIMSE 150
Cdd:PRK10909  91 QLIKNLATLK-AGNARVVNTN---ALSFLAQPGTPHNVVFVDPPFRKGLLEETINLLEDNGWLADEALIYVE 158
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 41-123 1.75e-09

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 54.18  E-value: 1.75e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  41 DGGIALDLFGGSGGLGIEAISRGIDkAIFVDRDNKAIKVIHQNLESCRIqEQAEVYRNDAERavkaLIKREISFDLILID 120
Cdd:COG1041   26 EGDTVLDPFCGTGTILIEAGLLGRR-VIGSDIDPKMVEGARENLEHYGY-EDADVIRGDARD----LPLADESVDAIVTD 99


                 ...
gi 872563064 121 PPY 123
Cdd:COG1041  100 PPY 102
RlmK COG1092
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure ...
 35-122 2.12e-09

23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure and biogenesis]; 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 440709 [Multi-domain]  Cd Length: 392  Bit Score: 55.57  E-value: 2.12e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  35 MIGPYFDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVIHQNLESCRIQEQAEVYRNDAERAVKALIKREISF 114
Cdd:COG1092  210 RVAELAKGKRVLNLFSYTGGFSVHAAAGGAKSVTSVDLSATALEWAKENAALNGLDDRHEFVQADAFDWLRELAREGERF 289


                 ....*...
gi 872563064 115 DLILIDPP 122
Cdd:COG1092  290 DLIILDPP 297
PRK04338 PRK04338
N(2),N(2)-dimethylguanosine tRNA methyltransferase; Provisional
 31-131 2.60e-07

N(2),N(2)-dimethylguanosine tRNA methyltransferase; Provisional


Pssm-ID: 235286  Cd Length: 382  Bit Score: 49.53  E-value: 2.60e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  31 SIFNMIGPYFDGGIALDLFGGSGGLGIE-AISRGIDKAIFVDRDNKAIKVIHQNLESCRIQEQaEVYRNDAEravkALIK 109
Cdd:PRK04338  47 LVLRAFGPKLPRESVLDALSASGIRGIRyALETGVEKVTLNDINPDAVELIKKNLELNGLENE-KVFNKDAN----ALLH 121

                         90       100
                 ....*....|....*....|....*..
gi 872563064 110 REISFDLILIDP-----PYKDQKIVSL 131
Cdd:PRK04338 122 EERKFDVVDIDPfgspaPFLDSAIRSV 148
TrmA COG2265
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ...
 42-122 5.56e-06

tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441866 [Multi-domain]  Cd Length: 377  Bit Score: 45.55  E-value: 5.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  42 GGIALDLFGGSGGLGIeAISRGIDKAIFVDRDNKAIKVIHQNLESCRIqEQAEVYRNDAERAVKALIKREiSFDLILIDP 121
Cdd:COG2265  234 GERVLDLYCGVGTFAL-PLARRAKKVIGVEIVPEAVEDARENARLNGL-KNVEFVAGDLEEVLPELLWGG-RPDVVVLDP 310


                 .
gi 872563064 122 P 122
Cdd:COG2265  311 P 311
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
40-122 7.82e-06

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 44.51  E-value: 7.82e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  40 FDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVIHQNLEscRIQEQAEVYRNDAERavkalIKREISFDLILI 119
Cdd:COG2263   44 IEGKTVLDLGCGTGMLAIGAALLGAKKVVGVDIDPEALEIARENAE--RLGVRVDFIRADVTR-----IPLGGSVDTVVM 116


                 ...
gi 872563064 120 DPP 122
Cdd:COG2263  117 NPP 119
PRK15128 PRK15128
23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI;
39-122 2.38e-05

23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI;


Pssm-ID: 185082 [Multi-domain]  Cd Length: 396  Bit Score: 43.67  E-value: 2.38e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  39 YFDGGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVIHQNLESCRIQ-EQAEVYRNDAERAVKALIKREISFDLI 117
Cdd:PRK15128 218 YVENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDlSKAEFVRDDVFKLLRTYRDRGEKFDVI 297


                 ....*
gi 872563064 118 LIDPP 122
Cdd:PRK15128 298 VMDPP 302
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 46-123 4.30e-05

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 40.88  E-value: 4.30e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 872563064  46 LDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVIHQNLEsCRIQEQAEVYRNDAEravKALIKREISFDLILIDPPY 123
Cdd:cd02440    3 LDLGCGTGALALALASGPGARVTGVDISPVALELARKAAA-ALLADNVEVLKGDAE---ELPPEADESFDVIISDPPL 76
TRM1 COG1867
tRNA G26 N,N-dimethylase Trm1 [Translation, ribosomal structure and biogenesis]; tRNA G26 N, ...
 44-121 1.46e-04

tRNA G26 N,N-dimethylase Trm1 [Translation, ribosomal structure and biogenesis]; tRNA G26 N,N-dimethylase Trm1 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441472  Cd Length: 383  Bit Score: 41.40  E-value: 1.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  44 IALDLFGGSGglgieaiSRGI-------DKAIFVDRDNKAIKVIHQNLESCRIqEQAEVYRNDAERavkALIKREISFDL 116
Cdd:COG1867   60 SYLDALAASG-------IRGLryalevgIKVTLNDIDPEAVELIRENLELNGL-EDVEVYNRDANA---LLHELGRRFDV 128


                 ....*
gi 872563064 117 ILIDP 121
Cdd:COG1867  129 VDLDP 133
PRK14968 PRK14968
putative methyltransferase; Provisional
 41-123 6.31e-04

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 38.73  E-value: 6.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  41 DGGIALDLFGGSGGLGIEAISRGIDkAIFVDRDNKAIKVIHQNLESCRIQEQA-EVYRNDAERAVkalikREISFDLILI 119
Cdd:PRK14968  23 KGDRVLEVGTGSGIVAIVAAKNGKK-VVGVDINPYAVECAKCNAKLNNIRNNGvEVIRSDLFEPF-----RGDKFDVILF 96


                 ....
gi 872563064 120 DPPY 123
Cdd:PRK14968  97 NPPY 100
Methyltransf_15 pfam09445
RNA cap guanine-N2 methyltransferase; RNA cap guanine-N2 methyltransferases such as ...
 42-140 1.02e-03

RNA cap guanine-N2 methyltransferase; RNA cap guanine-N2 methyltransferases such as Schizosaccharomyces pombe Tgs1 and Giardia lamblia Tgs2 catalyze methylation of the exocyclic N2 amine of 7-methylguanosine.


Pssm-ID: 370496  Cd Length: 165  Bit Score: 38.08  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   42 GGIALDLFGGSGGLGIeAISRGIDKAIFVDRDNKAIKVIHQNLESCRIQEQAEVYRNDAERAVKALIKREISFDLILIDP 121
Cdd:pfam09445   1 ATRILDVFCGGGGNTI-QFANVFDSVISIDINLEHLACAQHNAEVYGVSDRIWLIHGDWFELLAKLKFEKIKYDCVFASP 79

                          90       100
                  ....*....|....*....|....
gi 872563064  122 P-----YKDQKIVSLISVMDQHGL 140
Cdd:pfam09445  80 PwggpsYKKQNVYDLENKLQPYGL 103
PRK14967 PRK14967
putative methyltransferase; Provisional
 45-123 1.24e-03

putative methyltransferase; Provisional


Pssm-ID: 184931 [Multi-domain]  Cd Length: 223  Bit Score: 38.11  E-value: 1.24e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 872563064  45 ALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVIHQNLESCRIqeQAEVYRNDAERAVkalikREISFDLILIDPPY 123
Cdd:PRK14967  40 VLDLCTGSGALAVAAAAAGAGSVTAVDISRRAVRSARLNALLAGV--DVDVRRGDWARAV-----EFRPFDVVVSNPPY 111
UPF0020 pfam01170
Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated ...
 41-123 1.49e-03

Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated with the THUMP domain that also occurs with RNA modification domains.


Pssm-ID: 395932 [Multi-domain]  Cd Length: 184  Bit Score: 37.72  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   41 DGGIALDLFGGSGGLGIEA------------ISRGIDKAIFVDRDNKAIKVIHQNLESCRIQEQAEVYRNDAeravKALI 108
Cdd:pfam01170  28 PGDPLLDPMCGSGTILIEAalmganiapgkfDARVRAPLYGSDIDRRMVQGARLNAENAGVGDLIEFVQADA----ADLP 103

                          90
                  ....*....|....*
gi 872563064  109 KREISFDLILIDPPY 123
Cdd:pfam01170 104 LLEGSVDVIVTNPPY 118
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 41-130 3.70e-03

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 36.71  E-value: 3.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  41 DGGIALDLFGGSGGLGIEAISRGIDKAI-FVDRDNKAIKVIHQNLESCRIqEQAEVYRNDAERAVKalikrEISFDLILI 119
Cdd:COG2813   49 LGGRVLDLGCGYGVIGLALAKRNPEARVtLVDVNARAVELARANAAANGL-ENVEVLWSDGLSGVP-----DGSFDLILS 122

                         90
                 ....*....|.
gi 872563064 120 DPPYKDQKIVS 130
Cdd:COG2813  123 NPPFHAGRAVD 133
COG2521 COG2521
Predicted archaeal methyltransferase [General function prediction only];
42-122 4.21e-03

Predicted archaeal methyltransferase [General function prediction only];


Pssm-ID: 442011 [Multi-domain]  Cd Length: 285  Bit Score: 36.81  E-value: 4.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  42 GGIALDLFGGSGGLGIEAISRGIDKAIFVDRDNKAIKVIHQN-----LESCRIQeqaeVYRNDAERAVKALikREISFDL 116
Cdd:COG2521  133 GDRVLDTCTGLGYTAIEALKRGAREVITVEKDPNVLELAELNpwsreLANERIK----IILGDASEVIKTF--PDESFDA 206


                 ....*.
gi 872563064 117 ILIDPP 122
Cdd:COG2521  207 IIHDPP 212
L3_gln_methyl TIGR03533
protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific; Members of this ...
 45-126 5.32e-03

protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific; Members of this protein family methylate ribosomal protein L3 on a glutamine side chain. This family is related to HemK, a protein-glutamine methyltranferase for peptide chain release factors. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 274633 [Multi-domain]  Cd Length: 284  Bit Score: 36.72  E-value: 5.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   45 ALDLFGGSGGLGIEAISR----GIDKaifVDRDNKAIKVIHQNLESCRIQEQAEVYRNDAERAVKALikreiSFDLILID 120
Cdd:TIGR03533 125 ILDLCTGSGCIAIACAYAfpeaEVDA---VDISPDALAVAEINIERHGLEDRVTLIQSDLFAALPGR-----KYDLIVSN 196


                  ....*.
gi 872563064  121 PPYKDQ 126
Cdd:TIGR03533 197 PPYVDA 202
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
46-149 5.65e-03

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 36.30  E-value: 5.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064  46 LDlFG-GSGGLGIEAISRGIDKAIFVDRDNKAIKVIHQNLESCRIQEQAEVYRNDAERAVKalikreisFDL----ILID 120
Cdd:COG2264  153 LD-VGcGSGILAIAAAKLGAKRVLAVDIDPVAVEAARENAELNGVEDRIEVVLGDLLEDGP--------YDLvvanILAN 223

                         90       100       110
                 ....*....|....*....|....*....|
gi 872563064 121 PpykdqkIVSLISVMDQHglLHRDG-LIMS 149
Cdd:COG2264  224 P------LIELAPDLAAL--LKPGGyLILS 245
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 42-131 7.18e-03

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 35.64  E-value: 7.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872563064   42 GGIALDLFGGSGGLGIEAISRGIDKAI-FVDRDNKAIKVIHQNLESCRIqEQAEVYRNDAERAVKalikrEISFDLILID 120
Cdd:pfam05175  32 SGKVLDLGCGAGVLGAALAKESPDAELtMVDINARALESARENLAANGL-ENGEVVASDVYSGVE-----DGKFDLIISN 105

                          90
                  ....*....|.
gi 872563064  121 PPYKDQKIVSL 131
Cdd:pfam05175 106 PPFHAGLATTY 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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