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Conserved domains on  [gi|872683050|ref|WP_048543787|]
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MULTISPECIES: PadR family transcriptional regulator [Bacillus]

Protein Classification

PadR family transcriptional regulator( domain architecture ID 11447737)

PadR family transcriptional regulator similar to the phenolic acid decarboxylation repressor, which is a transcription factor that represses genes associated with the phenolic acid stress response in gram-positive bacteria

Gene Ontology:  GO:0003677|GO:0003700
PubMed:  10679470|10908318|10473770|15808743|8831795

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
5-101 1.90e-30

DNA-binding transcriptional regulator, PadR family [Transcription];


:

Pssm-ID: 441301  Cd Length: 102  Bit Score: 103.86  E-value: 1.90e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872683050   5 TEMLKGSLEGCVLEIISRRETYGYEITRHLNDL--GFTEVVEGTVYTILVRLEKKKLVNIEKKPSDMGPPRKFYSLNEEG 82
Cdd:COG1695    3 RQLRKGTLELLILALLAEGPMYGYEIIKELEERsgGFWKVSEGTLYPALKRLEKEGLVESEWEESEGGPRRKYYRLTEAG 82

                         90
                 ....*....|....*....
gi 872683050  83 RQELELFWKKWDFVSSKIN 101
Cdd:COG1695   83 REELAEWLEEWEKLAEALE 101
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
5-101 1.90e-30

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 103.86  E-value: 1.90e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872683050   5 TEMLKGSLEGCVLEIISRRETYGYEITRHLNDL--GFTEVVEGTVYTILVRLEKKKLVNIEKKPSDMGPPRKFYSLNEEG 82
Cdd:COG1695    3 RQLRKGTLELLILALLAEGPMYGYEIIKELEERsgGFWKVSEGTLYPALKRLEKEGLVESEWEESEGGPRRKYYRLTEAG 82

                         90
                 ....*....|....*....
gi 872683050  83 RQELELFWKKWDFVSSKIN 101
Cdd:COG1695   83 REELAEWLEEWEKLAEALE 101
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 16-87 9.51e-24

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 86.15  E-value: 9.51e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 872683050   16 VLEIISRRETYGYEITRHLNDL--GFTEVVEGTVYTILVRLEKKKLVNIEKKPSDMGPPRKFYSLNEEGRQELE 87
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEELsgGFWRPSEGTLYPILKRLEKEGLVESEWVDSGGGPPRKYYRLTDAGRRELA 74
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 8-100 4.39e-12

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 57.18  E-value: 4.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872683050    8 LKGSLEGCVLEIISRRETYGYEITRHLNDL--GFTEVVEGTVYTILVRLEKKKLVNIEKKPSDMGPPRKFYSLNEEGRQE 85
Cdd:TIGR03433   1 LQGTLDLLILKTLSLGPLHGYGIAQRIQQIseDVLQVEEGSLYPALHRLERRGWIAAEWGESENNRRAKFYRLTAAGRKQ 80

                          90
                  ....*....|....*
gi 872683050   86 LELFWKKWDFVSSKI 100
Cdd:TIGR03433  81 LAAETESWARLSAAI 95
lstR PRK09416
PadR family transcriptional regulator;
24-86 7.94e-04

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 36.30  E-value: 7.94e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 872683050  24 ETYGYEITRHLNDLGFT--EVVEGTVYTILVRLEKKKLVniekKPSDMGPPRKFYSLNEEGRQEL 86
Cdd:PRK09416  55 EKTGYELLQLLRQRGILtfEGNEGSLYTLLHRLEQNRFI----QSSWDHEGAKYYQLTDKGNKML 115
 
Name Accession Description Interval E-value
PadR COG1695
DNA-binding transcriptional regulator, PadR family [Transcription];
5-101 1.90e-30

DNA-binding transcriptional regulator, PadR family [Transcription];


Pssm-ID: 441301  Cd Length: 102  Bit Score: 103.86  E-value: 1.90e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872683050   5 TEMLKGSLEGCVLEIISRRETYGYEITRHLNDL--GFTEVVEGTVYTILVRLEKKKLVNIEKKPSDMGPPRKFYSLNEEG 82
Cdd:COG1695    3 RQLRKGTLELLILALLAEGPMYGYEIIKELEERsgGFWKVSEGTLYPALKRLEKEGLVESEWEESEGGPRRKYYRLTEAG 82

                         90
                 ....*....|....*....
gi 872683050  83 RQELELFWKKWDFVSSKIN 101
Cdd:COG1695   83 REELAEWLEEWEKLAEALE 101
PadR pfam03551
Transcriptional regulator PadR-like family; Members of this family are transcriptional ...
 16-87 9.51e-24

Transcriptional regulator PadR-like family; Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.


Pssm-ID: 397561  Cd Length: 74  Bit Score: 86.15  E-value: 9.51e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 872683050   16 VLEIISRRETYGYEITRHLNDL--GFTEVVEGTVYTILVRLEKKKLVNIEKKPSDMGPPRKFYSLNEEGRQELE 87
Cdd:pfam03551   1 VLAVLGEQPRYGYEIIKELEELsgGFWRPSEGTLYPILKRLEKEGLVESEWVDSGGGPPRKYYRLTDAGRRELA 74
padR_acidobact TIGR03433
transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are ...
 8-100 4.39e-12

transcriptional regulator, Acidobacterial, PadR-family; Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions]


Pssm-ID: 163261  Cd Length: 100  Bit Score: 57.18  E-value: 4.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 872683050    8 LKGSLEGCVLEIISRRETYGYEITRHLNDL--GFTEVVEGTVYTILVRLEKKKLVNIEKKPSDMGPPRKFYSLNEEGRQE 85
Cdd:TIGR03433   1 LQGTLDLLILKTLSLGPLHGYGIAQRIQQIseDVLQVEEGSLYPALHRLERRGWIAAEWGESENNRRAKFYRLTAAGRKQ 80

                          90
                  ....*....|....*
gi 872683050   86 LELFWKKWDFVSSKI 100
Cdd:TIGR03433  81 LAAETESWARLSAAI 95
lstR PRK09416
PadR family transcriptional regulator;
24-86 7.94e-04

PadR family transcriptional regulator;


Pssm-ID: 181836  Cd Length: 135  Bit Score: 36.30  E-value: 7.94e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 872683050  24 ETYGYEITRHLNDLGFT--EVVEGTVYTILVRLEKKKLVniekKPSDMGPPRKFYSLNEEGRQEL 86
Cdd:PRK09416  55 EKTGYELLQLLRQRGILtfEGNEGSLYTLLHRLEQNRFI----QSSWDHEGAKYYQLTDKGNKML 115
COG1777 COG1777
Predicted transcriptional regulator, ArsR family [Transcription];
16-81 1.02e-03

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441383  Cd Length: 113  Bit Score: 35.78  E-value: 1.02e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 872683050  16 VLEIISRRETYGYEITRHLndlgftEVVEGTVYTILVRLEKKKLVNIEKKPSDMGPPRKFYSLNEE 81
Cdd:COG1777   22 ILALLSEEPAYVSELAREL------GVSRQAVYKHLRKLEEAGLVESYREGREDGRARKYYRLSAF 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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