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Conserved domains on  [gi|873903947|ref|WP_048610280|]
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MULTISPECIES: tetratricopeptide repeat protein [Vibrio]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11434433)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
33-135 2.27e-18

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 78.05  E-value: 2.27e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 873903947  33 AATMDQSQQHQDVVQLLDEAYQGQLDAQLSVAYLYLSGEGVEQNDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQAS 112
Cdd:COG0790   39 AALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQD 118

                         90       100
                 ....*....|....*....|...
gi 873903947 113 QAEAVTWIGMAAAQEYDPALDLL 135
Cdd:COG0790  119 YAKALEWYEKAAEQGDADAQYNL 141
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
33-135 2.27e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 78.05  E-value: 2.27e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 873903947  33 AATMDQSQQHQDVVQLLDEAYQGQLDAQLSVAYLYLSGEGVEQNDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQAS 112
Cdd:COG0790   39 AALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQD 118

                         90       100
                 ....*....|....*....|...
gi 873903947 113 QAEAVTWIGMAAAQEYDPALDLL 135
Cdd:COG0790  119 YAKALEWYEKAAEQGDADAQYNL 141
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 58-91 1.80e-05

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 39.43  E-value: 1.80e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 873903947   58 DAQLSVAYLYLSGEGVEQNDEKAAEWFVTAANNG 91
Cdd:pfam08238   2 EAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 58-92 1.74e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 36.77  E-value: 1.74e-04
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 873903947    58 DAQLSVAYLYLSGEGVEQNDEKAAEWFVTAANNGS 92
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
33-135 2.27e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 78.05  E-value: 2.27e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 873903947  33 AATMDQSQQHQDVVQLLDEAYQGQLDAQLSVAYLYLSGEGVEQNDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQAS 112
Cdd:COG0790   39 AALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQD 118

                         90       100
                 ....*....|....*....|...
gi 873903947 113 QAEAVTWIGMAAAQEYDPALDLL 135
Cdd:COG0790  119 YAKALEWYEKAAEQGDADAQYNL 141
TPR COG0790
TPR repeat [General function prediction only];
52-138 2.98e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 77.66  E-value: 2.98e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 873903947  52 AYQGQLDAQLSVAYLYLSGEGVEQNDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQASQAEAVTWIGMAAAQEYDPA 131
Cdd:COG0790   94 AEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADA 173


                 ....*..
gi 873903947 132 LDLLHWM 138
Cdd:COG0790  174 QYNLGVL 180
TPR COG0790
TPR repeat [General function prediction only];
52-138 3.99e-18

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 77.28  E-value: 3.99e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 873903947  52 AYQGQLDAQLSVAYLYLSGEGVEQNDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQASQAEAVTWIGMAAAQEYDPA 131
Cdd:COG0790  130 AEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADA 209


                 ....*..
gi 873903947 132 LDLLHWM 138
Cdd:COG0790  210 QYNLGRL 216
TPR COG0790
TPR repeat [General function prediction only];
52-126 1.22e-14

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 68.03  E-value: 1.22e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 873903947  52 AYQGQLDAQLSVAYLYLSGEGVEQNDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQASQAEAVTWIGMAAAQ 126
Cdd:COG0790  166 AEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
48-138 5.86e-06

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 44.15  E-value: 5.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 873903947  48 LLDEAYQGQLDAQLSVAYLYLSGEGVEQNDEKAAEWFVTAANNGSPEAQTQLGLMYISGSGVQASQAEAVTWIGMAAAQE 127
Cdd:COG0790   18 LAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQG 97

                         90
                 ....*....|.
gi 873903947 128 YDPALDLLHWM 138
Cdd:COG0790   98 DAEAQYNLGLM 108
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 58-91 1.80e-05

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 39.43  E-value: 1.80e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 873903947   58 DAQLSVAYLYLSGEGVEQNDEKAAEWFVTAANNG 91
Cdd:pfam08238   2 EAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 58-92 1.74e-04

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 36.77  E-value: 1.74e-04
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 873903947    58 DAQLSVAYLYLSGEGVEQNDEKAAEWFVTAANNGS 92
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 93-128 2.95e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 33.69  E-value: 2.95e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 873903947    93 PEAQTQLGLMYISGSGVQASQAEAVTWIGMAAAQEY 128
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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