|
Name |
Accession |
Description |
Interval |
E-value |
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
1-807 |
0e+00 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 1393.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 1 MSSGQSFSRSLMKLPLSVLVKGTSIPSNPVEDLNIDLSKPIVYSLPFRSSVDILTLQKHALELGLPDPLSKLEINGKSLQ 80
Cdd:PRK04974 1 MSGWRRLYYKLLNLPLKLLVKSKVIPADPAEELGLDPSRPIVYVLPYNSLSDLLTLRKQCLKLGLPDPLEPLEINGLQLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 81 RYVFISSRKTLLQDDDyVPSSSIEVFSELLSLHADDSELDVQVIPATVLWGRKPGKENNQKPYLQAMNG-----LEKSKA 155
Cdd:PRK04974 81 RYVFLHGGPRLFGYRT-PKEESSPLFHRLLDLHRQNPELDVQLVPVSVFWGRAPGKEDSELRLLNGDNWavpgrLRKLFA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 156 VLLAGRDCLVRFSPVVSLRYMANSHGTDSTIAHKLARVARIHFSRQKLAASGPNLPSRQALFDRLLKSEAIKKAIEDEAQ 235
Cdd:PRK04974 160 ILWLGRDTFVRFSPPVSLRYMADEHGTDKRIARKLARVARVHFRRQRLAAIGPDLPHRQALFNKLLASPAIKKAIEDEAK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 236 AKNISIEKASKEAQDIMDEIAANFSYSLIKRGEKILGWLWNKLYQGLHISNASTVRKLAQDGHEIVYVPCHRSHMDYLLL 315
Cdd:PRK04974 240 SKKISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVHNAERVRQLAQDGHEIVYVPCHRSHMDYLLL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 316 SYVLYHEGMVPPHIAAGINLNFFPAGPIFRHGGAFFIRRSFKGNKLYSTIFREYLAELFAKGYSVEYFSEGGRSRTGRLL 395
Cdd:PRK04974 320 SYVLYHQGLVPPHIAAGINLNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFARGYSVEYFVEGGRSRTGRLL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 396 QAKTGMLAMTIQAMLRGMNRPVTLVPVYIGYEHVMEVATYAKELRGKRKEKENASLVIRTIRKLRNFGKGYVNFGEPIQL 475
Cdd:PRK04974 400 QPKTGMLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLRGIRKLRNFGQGYVNFGEPIPL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 476 NQYLNEHSPEWTKDIDPMGTSKPQWMNPVVNDLATKMMTHINDAAATNALTLCATALLASRQRALSRDSLVSQINCYLSL 555
Cdd:PRK04974 480 NDYLNQHVPEWRESIDPIEEQRPAWLTPAVNNLANQVMVRINNAAAANPVNLCALALLASRQRALDREQLIEQLDLYLQL 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 556 LKNVPYSATFTVPKDSAEELVKHAESLNKFLIESDSMGDIISLDRHQSILMTYYRNNIIHLFALPSLIAQMTIRQRGLSI 635
Cdd:PRK04974 560 LRNVPYSSDTTVPEGSGEELIDHALSLNKFEVEKDTLGDIISLDREQAVLMTYYRNNILHLFVLPSLIASIVTHNRRISR 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 636 DAIQENVATIYPFLKKELFLSYEEDKLEGVVSNIIEELVNQGMLVISDNEVTINQSNSQALMLLGRTISETLQRYSIALN 715
Cdd:PRK04974 640 DELLRIVNALYPFLKAELFLRWDEEELPEVIDQIIDELVRQGLITLDDDELHINPPRSRELQLLAAGVRETLQRYAITLS 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 716 LLAENPDLDKSDLEQKSQDIAQRLGRLQGINAPEFFDKGVFASMFATLKQQQYLDND--GNCDLEKTQQFAKLLYSMLYP 793
Cdd:PRK04974 720 LLSGSPNISRSELEKESHLLAQRLSVLHGINAPEFFDKALFSSFIQTLREEGYIRDDdsGDLEFEETLEIYAILKRLLSP 799
|
810
....*....|....
gi 880811188 794 EVRLTIQESIHQAE 807
Cdd:PRK04974 800 EVRLTIEQVAQAEE 813
|
|
| plsB |
TIGR03703 |
glycerol-3-phosphate O-acyltransferase; Members of this protein family are PlsB, ... |
11-799 |
0e+00 |
|
glycerol-3-phosphate O-acyltransferase; Members of this protein family are PlsB, glycerol-3-phosphate O-acyltransferase, present in E. coli and numerous related species. In many bacteria, PlsB is not found, and appears to be replaced by a two enzyme system for 1-acyl-glycerol-3-phosphate biosynthesis, the PlsX/Y system. [Fatty acid and phospholipid metabolism, Biosynthesis]
Pssm-ID: 274732 [Multi-domain] Cd Length: 799 Bit Score: 1301.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 11 LMKLPLSVLVKGTSIPSNPVEDLNIDLSKPIVYSLPFRSSVDILTLQKHALELGLPDPLSKLEINGKSLQRYVFISSRKT 90
Cdd:TIGR03703 1 LLRLPLSLLVRSKVIPSDPIQELGLDPERPIVYVLPTRSLSDLLALQKACRKLGLPDPLEPLVIGGQRLPRYVFLDRPPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 91 LLQDDDyVPSSSIEVFSELLSLHADDSELDVQVIPATVLWGRKPGKENNQKPYLQAM-----NGLEKSKAVLLAGRDCLV 165
Cdd:TIGR03703 81 LFSDRQ-KKSTSLPLLHRLLELHREDPELDVQLVPVSVFWGRAPGKESSGWKLLFLDswaspGRLRKFLIVLFLGRDNFV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 166 RFSPVVSLRYMANSHGTDSTIAHKLARVARIHFSRQKLAASGPNLPSRQALFDRLLKSEAIKKAIEDEAQAKNISIEKAS 245
Cdd:TIGR03703 160 RFSPPVSLRYMADEHGTDESIAHKLARVARVHFRRQRLAAIGPDLSHRRTLFNKLLASPSVRKAIRDEAKSKKISEEKAR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 246 KEAQDIMDEIAANFSYSLIKRGEKILGWLWNKLYQGLHISNASTVRKLAQDGHEIVYVPCHRSHMDYLLLSYVLYHEGMV 325
Cdd:TIGR03703 240 KRALKYLDEIAADYSYSLIRFLDRFLTWLWNKLYQGINVNNADRVRKLAQKGHEIIYVPCHRSHMDYLLLSYVLYHEGLV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 326 PPHIAAGINLNFFPAGPIFRHGGAFFIRRSFKGNKLYSTIFREYLAELFAKGYSVEYFSEGGRSRTGRLLQAKTGMLAMT 405
Cdd:TIGR03703 320 PPHIAAGINLNFWPAGPIFRRGGAFFIRRSFKGNKLYSAVFREYLHELFAKGYSVEYFVEGGRSRTGRLLPPKTGMLAMT 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 406 IQAMLRGMNRPVTLVPVYIGYEHVMEVATYAKELRGKRKEKENASLVIRTIRKLRNFGKGYVNFGEPIQLNQYLNEHSPE 485
Cdd:TIGR03703 400 LQAMLRGIRRPITLVPVYIGYEHVMEVATYLKELRGKRKEKESVFGVLKTLRKLRNFGQGYVNFGEPINLNDYLNKHVPN 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 486 WTKDIDPMGTSKPQWMNPVVNDLATKMMTHINDAAATNALTLCATALLASRQRALSRDSLVSQINCYLSLLKNVPYSATF 565
Cdd:TIGR03703 480 WRDDINPIEEEKPTWLTPAVNELANQVMTRINNAAAVNAVNLCALALLASRKHALSREELLAQLDLYLSLLRNVPYSERS 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 566 TVPKDSAEELVKHAESLNKFLIESDSMGDIISLDRHQSILMTYYRNNIIHLFALPSLIAQMTIRQRGLSIDAIQENVATI 645
Cdd:TIGR03703 560 TVPEEDPEELLEHALELNKFTVEEDSLGEIISLDREQAVLMTYYRNNILHLFALPSLVASIVIHNKKISRAELQALVRLL 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 646 YPFLKKELFLSYEEDKLEGVVSNIIEELVNQGMLVISDNEVTINQSNSQA---LMLLGRTISETLQRYSIALNLLAENPD 722
Cdd:TIGR03703 640 YPLLKAELFLRWSEEELPEVIDRILDELVRQGLIEQDGDVLTRNAARSREfvqLQLLAASIQETLQRYAITLSLLQRSGS 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 723 LDKSDLEQKSQDIAQRLGRLQGINAPEFFDKGVFASMFATLKQQQYLDNDGNCDL---EKTQQFAKLLYSMLYPEVRLTI 799
Cdd:TIGR03703 720 ISRDALEKQSQQLAQRLSVLHGINAPEFFDKAVFSTFIATLREQGYLDDDGDGKLifdEKLEELADQLKALLSPEVRQTI 799
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
11-804 |
0e+00 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 975.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 11 LMKLPLSVLVKGTSIPSNPvEDLNIDLSKPIVYSLPFRSSVDILTLQKHALELGLPDPlskleingkslqryvfissrkt 90
Cdd:COG2937 2 LLRLPLKLLVKSKVIPEDT-AELELDPSKPVVYVLPYRSLSDLLVLRRQCRKLGLPDP---------------------- 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 91 llqdddyvpsssievfsellslhaddseldVQVIPATVLWgrkpgkennqkpylqamnglekskavllagrdCLVRFSPV 170
Cdd:COG2937 59 ------------------------------IQLVPVSVLW--------------------------------TFVRFGEP 76
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 171 VSLRYMANSHGTDSTIAHKLARVARIHFSRQKLAASGPNLPSRQALFDRLLKSEAIKKAIEDEAQAKNISIEKASKEAQD 250
Cdd:COG2937 77 VSLRELLDEGGSDERLARKLARVLRVHFRRQRRAVIGPDLKHRRDLIERLLRSPAVRKAIEEEAKSKGISEEKARKEARR 156
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 251 IMDEIAANFSYSLIKRGEKILGWLWNKLYQGLHISNASTVRKLAqDGHEIVYVPCHRSHMDYLLLSYVLYHEGMVPPHIA 330
Cdd:COG2937 157 YLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVDNLERLRELA-KGHEIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIA 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 331 AGINLNFFPAGPIFRHGGAFFIRRSFKGNKLYSTIFREYLAELFAKGYSVEYFSEGGRSRTGRLLQAKTGMLAMTIQAML 410
Cdd:COG2937 236 AGINLNFWPLGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFERGYSVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFL 315
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 411 RGMNRPVTLVPVYIGYEHVMEVATYAKELRGKRKEKENASLVIRTIRKLR-NFGKGYVNFGEPIQLNQYLNEHSPEWTKD 489
Cdd:COG2937 316 RGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLRALRKLRrRFGRVYVNFGEPISLSEYLDQHVPDWRES 395
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 490 IDpmgtSKPQWMNPVVNDLATKMMTHINDAAATNALTLCATALLASRQRALSRDSLVSQINCYLSLLKNVPYSATFTVPK 569
Cdd:COG2937 396 ED----LRPEWLRPAVDKLAFEIMVRINRAAAVNPVNLVALALLASPKRALTEAELLAQLDLYLDLLRNVPYSLSVTLPE 471
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 570 DSAEELVKHAESLNKFLIESDSMGDIISLDRHQSILMTYYRNNIIHLFALPSLIAQMTIRQRGLSIDAIQENVATIYPFL 649
Cdd:COG2937 472 LTPEELLEHLLSLGLIEVEKDGLGDVISIDDEQAVLLTYYRNNILHLFALPALIASALLANRRISRAELLELVRLLYPLL 551
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 650 KKELFLSYEEDkLEGVVSNIIEELVNQGMLVISDNEVTINQSNSQALMLLGRTISETLQRYSIALNLLAEN--PDLDKSD 727
Cdd:COG2937 552 KAELFLRWDAE-FEEVLDEELDELVRQGLLEREGDTLRRPPARFRQLQLLAHVLRETLERYAIVLSLLAKLgsGTLDRKE 630
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 880811188 728 LEQKSQDIAQRLGRLQGINAPEFFDKGVFASMFATLKQQQYLDNDGNCDLEKTQQFAKLLYSMLYPEVRLTIQESIH 804
Cdd:COG2937 631 LEKESLLLAQRLSLLHGINAPEFFDKALFRNFIQTLREQGYLDDDEDGKDEKLEELADDARELLSPELRQTIQRIAR 707
|
|
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
279-480 |
4.74e-83 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 263.66 E-value: 4.74e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 279 YQGLHISNAST--VRKLAQDGHEIVYVPCHRSHMDYLLLSYVLYHEGMVPPHIAAGINLNFFPAGPIFRHGGAFFIRRSF 356
Cdd:cd07993 1 FDGVQVNEGQLerLRKAAQEGHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIPILGTLLRRLGAFFIRRSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 357 KGNKLYSTIFREYLAELFAKGYSVEYFSEGGRSRTGRLLQAKTGMLAMTIQAMLRGMNRPVTLVPVYIGYEHVMEVATYA 436
Cdd:cd07993 81 GKDPLYRAVLQEYVQELLKNGQPLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEELYA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 880811188 437 KELRGKRKEKENASLVIRTIRKLR-NFGKGYVNFGEPIQLNQYLN 480
Cdd:cd07993 161 EELLGPPKPKESLSGLLGASKILReNFGRIRVDFGEPISLREYLG 205
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
295-425 |
8.52e-32 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 120.46 E-value: 8.52e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 295 QDGHEIVYVPCHRSHMDYLLLSYVLYHEGmVPPHIAAGINLNFFP-AGPIFRHGGAFFIRRsfkGNKLYSTIFREYLAEL 373
Cdd:pfam01553 11 PRGGPAIVVANHQSYLDVLLLSLALYKRG-RPLVFVAKKELFDIPlVGWLMRLLGCIFIDR---KNRKDAAGTLEYLVEL 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 880811188 374 FAKGYSVEYFSEGGRSRTGRLLQAKTGMLAMTIQAmlrgmnrPVTLVPVYIG 425
Cdd:pfam01553 87 LREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEA-------GVPIVPVAIS 131
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
300-426 |
1.05e-25 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 102.43 E-value: 1.05e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 300 IVYVPCHRSHMDYLLLSYVLYHEGMVPPHIAAGINLNFFPAGPIFRHGGAFFIRRSFKgnKLYSTIFREYLaELFAKGYS 379
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNG--RKARAALREAV-ELLKEGEW 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 880811188 380 VEYFSEGGRSRTGRLLQAKTGMLAMTIQAmlrgmnrPVTLVPVYIGY 426
Cdd:smart00563 78 LLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRG 117
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
1-807 |
0e+00 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 1393.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 1 MSSGQSFSRSLMKLPLSVLVKGTSIPSNPVEDLNIDLSKPIVYSLPFRSSVDILTLQKHALELGLPDPLSKLEINGKSLQ 80
Cdd:PRK04974 1 MSGWRRLYYKLLNLPLKLLVKSKVIPADPAEELGLDPSRPIVYVLPYNSLSDLLTLRKQCLKLGLPDPLEPLEINGLQLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 81 RYVFISSRKTLLQDDDyVPSSSIEVFSELLSLHADDSELDVQVIPATVLWGRKPGKENNQKPYLQAMNG-----LEKSKA 155
Cdd:PRK04974 81 RYVFLHGGPRLFGYRT-PKEESSPLFHRLLDLHRQNPELDVQLVPVSVFWGRAPGKEDSELRLLNGDNWavpgrLRKLFA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 156 VLLAGRDCLVRFSPVVSLRYMANSHGTDSTIAHKLARVARIHFSRQKLAASGPNLPSRQALFDRLLKSEAIKKAIEDEAQ 235
Cdd:PRK04974 160 ILWLGRDTFVRFSPPVSLRYMADEHGTDKRIARKLARVARVHFRRQRLAAIGPDLPHRQALFNKLLASPAIKKAIEDEAK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 236 AKNISIEKASKEAQDIMDEIAANFSYSLIKRGEKILGWLWNKLYQGLHISNASTVRKLAQDGHEIVYVPCHRSHMDYLLL 315
Cdd:PRK04974 240 SKKISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVHNAERVRQLAQDGHEIVYVPCHRSHMDYLLL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 316 SYVLYHEGMVPPHIAAGINLNFFPAGPIFRHGGAFFIRRSFKGNKLYSTIFREYLAELFAKGYSVEYFSEGGRSRTGRLL 395
Cdd:PRK04974 320 SYVLYHQGLVPPHIAAGINLNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFARGYSVEYFVEGGRSRTGRLL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 396 QAKTGMLAMTIQAMLRGMNRPVTLVPVYIGYEHVMEVATYAKELRGKRKEKENASLVIRTIRKLRNFGKGYVNFGEPIQL 475
Cdd:PRK04974 400 QPKTGMLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLRGIRKLRNFGQGYVNFGEPIPL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 476 NQYLNEHSPEWTKDIDPMGTSKPQWMNPVVNDLATKMMTHINDAAATNALTLCATALLASRQRALSRDSLVSQINCYLSL 555
Cdd:PRK04974 480 NDYLNQHVPEWRESIDPIEEQRPAWLTPAVNNLANQVMVRINNAAAANPVNLCALALLASRQRALDREQLIEQLDLYLQL 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 556 LKNVPYSATFTVPKDSAEELVKHAESLNKFLIESDSMGDIISLDRHQSILMTYYRNNIIHLFALPSLIAQMTIRQRGLSI 635
Cdd:PRK04974 560 LRNVPYSSDTTVPEGSGEELIDHALSLNKFEVEKDTLGDIISLDREQAVLMTYYRNNILHLFVLPSLIASIVTHNRRISR 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 636 DAIQENVATIYPFLKKELFLSYEEDKLEGVVSNIIEELVNQGMLVISDNEVTINQSNSQALMLLGRTISETLQRYSIALN 715
Cdd:PRK04974 640 DELLRIVNALYPFLKAELFLRWDEEELPEVIDQIIDELVRQGLITLDDDELHINPPRSRELQLLAAGVRETLQRYAITLS 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 716 LLAENPDLDKSDLEQKSQDIAQRLGRLQGINAPEFFDKGVFASMFATLKQQQYLDND--GNCDLEKTQQFAKLLYSMLYP 793
Cdd:PRK04974 720 LLSGSPNISRSELEKESHLLAQRLSVLHGINAPEFFDKALFSSFIQTLREEGYIRDDdsGDLEFEETLEIYAILKRLLSP 799
|
810
....*....|....
gi 880811188 794 EVRLTIQESIHQAE 807
Cdd:PRK04974 800 EVRLTIEQVAQAEE 813
|
|
| plsB |
TIGR03703 |
glycerol-3-phosphate O-acyltransferase; Members of this protein family are PlsB, ... |
11-799 |
0e+00 |
|
glycerol-3-phosphate O-acyltransferase; Members of this protein family are PlsB, glycerol-3-phosphate O-acyltransferase, present in E. coli and numerous related species. In many bacteria, PlsB is not found, and appears to be replaced by a two enzyme system for 1-acyl-glycerol-3-phosphate biosynthesis, the PlsX/Y system. [Fatty acid and phospholipid metabolism, Biosynthesis]
Pssm-ID: 274732 [Multi-domain] Cd Length: 799 Bit Score: 1301.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 11 LMKLPLSVLVKGTSIPSNPVEDLNIDLSKPIVYSLPFRSSVDILTLQKHALELGLPDPLSKLEINGKSLQRYVFISSRKT 90
Cdd:TIGR03703 1 LLRLPLSLLVRSKVIPSDPIQELGLDPERPIVYVLPTRSLSDLLALQKACRKLGLPDPLEPLVIGGQRLPRYVFLDRPPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 91 LLQDDDyVPSSSIEVFSELLSLHADDSELDVQVIPATVLWGRKPGKENNQKPYLQAM-----NGLEKSKAVLLAGRDCLV 165
Cdd:TIGR03703 81 LFSDRQ-KKSTSLPLLHRLLELHREDPELDVQLVPVSVFWGRAPGKESSGWKLLFLDswaspGRLRKFLIVLFLGRDNFV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 166 RFSPVVSLRYMANSHGTDSTIAHKLARVARIHFSRQKLAASGPNLPSRQALFDRLLKSEAIKKAIEDEAQAKNISIEKAS 245
Cdd:TIGR03703 160 RFSPPVSLRYMADEHGTDESIAHKLARVARVHFRRQRLAAIGPDLSHRRTLFNKLLASPSVRKAIRDEAKSKKISEEKAR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 246 KEAQDIMDEIAANFSYSLIKRGEKILGWLWNKLYQGLHISNASTVRKLAQDGHEIVYVPCHRSHMDYLLLSYVLYHEGMV 325
Cdd:TIGR03703 240 KRALKYLDEIAADYSYSLIRFLDRFLTWLWNKLYQGINVNNADRVRKLAQKGHEIIYVPCHRSHMDYLLLSYVLYHEGLV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 326 PPHIAAGINLNFFPAGPIFRHGGAFFIRRSFKGNKLYSTIFREYLAELFAKGYSVEYFSEGGRSRTGRLLQAKTGMLAMT 405
Cdd:TIGR03703 320 PPHIAAGINLNFWPAGPIFRRGGAFFIRRSFKGNKLYSAVFREYLHELFAKGYSVEYFVEGGRSRTGRLLPPKTGMLAMT 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 406 IQAMLRGMNRPVTLVPVYIGYEHVMEVATYAKELRGKRKEKENASLVIRTIRKLRNFGKGYVNFGEPIQLNQYLNEHSPE 485
Cdd:TIGR03703 400 LQAMLRGIRRPITLVPVYIGYEHVMEVATYLKELRGKRKEKESVFGVLKTLRKLRNFGQGYVNFGEPINLNDYLNKHVPN 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 486 WTKDIDPMGTSKPQWMNPVVNDLATKMMTHINDAAATNALTLCATALLASRQRALSRDSLVSQINCYLSLLKNVPYSATF 565
Cdd:TIGR03703 480 WRDDINPIEEEKPTWLTPAVNELANQVMTRINNAAAVNAVNLCALALLASRKHALSREELLAQLDLYLSLLRNVPYSERS 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 566 TVPKDSAEELVKHAESLNKFLIESDSMGDIISLDRHQSILMTYYRNNIIHLFALPSLIAQMTIRQRGLSIDAIQENVATI 645
Cdd:TIGR03703 560 TVPEEDPEELLEHALELNKFTVEEDSLGEIISLDREQAVLMTYYRNNILHLFALPSLVASIVIHNKKISRAELQALVRLL 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 646 YPFLKKELFLSYEEDKLEGVVSNIIEELVNQGMLVISDNEVTINQSNSQA---LMLLGRTISETLQRYSIALNLLAENPD 722
Cdd:TIGR03703 640 YPLLKAELFLRWSEEELPEVIDRILDELVRQGLIEQDGDVLTRNAARSREfvqLQLLAASIQETLQRYAITLSLLQRSGS 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 723 LDKSDLEQKSQDIAQRLGRLQGINAPEFFDKGVFASMFATLKQQQYLDNDGNCDL---EKTQQFAKLLYSMLYPEVRLTI 799
Cdd:TIGR03703 720 ISRDALEKQSQQLAQRLSVLHGINAPEFFDKAVFSTFIATLREQGYLDDDGDGKLifdEKLEELADQLKALLSPEVRQTI 799
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
11-804 |
0e+00 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 975.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 11 LMKLPLSVLVKGTSIPSNPvEDLNIDLSKPIVYSLPFRSSVDILTLQKHALELGLPDPlskleingkslqryvfissrkt 90
Cdd:COG2937 2 LLRLPLKLLVKSKVIPEDT-AELELDPSKPVVYVLPYRSLSDLLVLRRQCRKLGLPDP---------------------- 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 91 llqdddyvpsssievfsellslhaddseldVQVIPATVLWgrkpgkennqkpylqamnglekskavllagrdCLVRFSPV 170
Cdd:COG2937 59 ------------------------------IQLVPVSVLW--------------------------------TFVRFGEP 76
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 171 VSLRYMANSHGTDSTIAHKLARVARIHFSRQKLAASGPNLPSRQALFDRLLKSEAIKKAIEDEAQAKNISIEKASKEAQD 250
Cdd:COG2937 77 VSLRELLDEGGSDERLARKLARVLRVHFRRQRRAVIGPDLKHRRDLIERLLRSPAVRKAIEEEAKSKGISEEKARKEARR 156
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 251 IMDEIAANFSYSLIKRGEKILGWLWNKLYQGLHISNASTVRKLAqDGHEIVYVPCHRSHMDYLLLSYVLYHEGMVPPHIA 330
Cdd:COG2937 157 YLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVDNLERLRELA-KGHEIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIA 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 331 AGINLNFFPAGPIFRHGGAFFIRRSFKGNKLYSTIFREYLAELFAKGYSVEYFSEGGRSRTGRLLQAKTGMLAMTIQAML 410
Cdd:COG2937 236 AGINLNFWPLGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFERGYSVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFL 315
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 411 RGMNRPVTLVPVYIGYEHVMEVATYAKELRGKRKEKENASLVIRTIRKLR-NFGKGYVNFGEPIQLNQYLNEHSPEWTKD 489
Cdd:COG2937 316 RGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLRALRKLRrRFGRVYVNFGEPISLSEYLDQHVPDWRES 395
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 490 IDpmgtSKPQWMNPVVNDLATKMMTHINDAAATNALTLCATALLASRQRALSRDSLVSQINCYLSLLKNVPYSATFTVPK 569
Cdd:COG2937 396 ED----LRPEWLRPAVDKLAFEIMVRINRAAAVNPVNLVALALLASPKRALTEAELLAQLDLYLDLLRNVPYSLSVTLPE 471
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 570 DSAEELVKHAESLNKFLIESDSMGDIISLDRHQSILMTYYRNNIIHLFALPSLIAQMTIRQRGLSIDAIQENVATIYPFL 649
Cdd:COG2937 472 LTPEELLEHLLSLGLIEVEKDGLGDVISIDDEQAVLLTYYRNNILHLFALPALIASALLANRRISRAELLELVRLLYPLL 551
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 650 KKELFLSYEEDkLEGVVSNIIEELVNQGMLVISDNEVTINQSNSQALMLLGRTISETLQRYSIALNLLAEN--PDLDKSD 727
Cdd:COG2937 552 KAELFLRWDAE-FEEVLDEELDELVRQGLLEREGDTLRRPPARFRQLQLLAHVLRETLERYAIVLSLLAKLgsGTLDRKE 630
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 880811188 728 LEQKSQDIAQRLGRLQGINAPEFFDKGVFASMFATLKQQQYLDNDGNCDLEKTQQFAKLLYSMLYPEVRLTIQESIH 804
Cdd:COG2937 631 LEKESLLLAQRLSLLHGINAPEFFDKALFRNFIQTLREQGYLDDDEDGKDEKLEELADDARELLSPELRQTIQRIAR 707
|
|
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
279-480 |
4.74e-83 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 263.66 E-value: 4.74e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 279 YQGLHISNAST--VRKLAQDGHEIVYVPCHRSHMDYLLLSYVLYHEGMVPPHIAAGINLNFFPAGPIFRHGGAFFIRRSF 356
Cdd:cd07993 1 FDGVQVNEGQLerLRKAAQEGHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIPILGTLLRRLGAFFIRRSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 357 KGNKLYSTIFREYLAELFAKGYSVEYFSEGGRSRTGRLLQAKTGMLAMTIQAMLRGMNRPVTLVPVYIGYEHVMEVATYA 436
Cdd:cd07993 81 GKDPLYRAVLQEYVQELLKNGQPLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEELYA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 880811188 437 KELRGKRKEKENASLVIRTIRKLR-NFGKGYVNFGEPIQLNQYLN 480
Cdd:cd07993 161 EELLGPPKPKESLSGLLGASKILReNFGRIRVDFGEPISLREYLG 205
|
|
| PRK03355 |
PRK03355 |
glycerol-3-phosphate 1-O-acyltransferase; |
174-765 |
5.09e-57 |
|
glycerol-3-phosphate 1-O-acyltransferase;
Pssm-ID: 179567 [Multi-domain] Cd Length: 783 Bit Score: 209.18 E-value: 5.09e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 174 RYMANSHGTDS-TIAHKLARVARIHFSRQKLAASGPNLPSRQALFDRLLKSEAIKKAIEDEAQAKNISIEKASKEAQDIM 252
Cdd:PRK03355 141 RWRDTTVGENSrDFARFVRRRAALALERAERRILGPQYKVPRLVKPEILASARFRAGLAKIAAKLGRPPGATVREAGKML 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 253 DEIAAN---FSYSLIKRGEKIL--GWLWNKLYqglhisNASTVRKL--AQDGHEIVYVPCHRSHMDYLLLSYVLYHEGMV 325
Cdd:PRK03355 221 DELVAGwsrVSVDLVSVLGRLFsrGFDPEIDY------DEYELAALraLLEEHPAVLLFSHRSYIDGLVVPVAMQENRLP 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 326 PPHIAAGINLNFFPAGPIFRHGGAFFIRRSFKGNKLYSTIFREYLAELFAKGYSVEYFSEGGRSRTGRLLQAKTGMLAMT 405
Cdd:PRK03355 295 PVHVFGGINLSFGPMGPIMRRSGMIFIRRNIGDDPLYKYVLREYVGYLVEKRFNLSWYIEGTRSRTGKLLPPKLGLLSYV 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 406 IQAMLRGMNRPVTLVPVYIGYEHVMEVATYAKELRGKRKEKENASLVIRTIRKL--RNFGKGYVNFGEPIQLNQYLNEHS 483
Cdd:PRK03355 375 ADAYLDGRSDDVLLQPVSISFDQLHEIGEYAAEARGGEKTPEGLRWLYNYIKAQgeRNYGKIYVRFGEPVSMRQYLGAPH 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 484 PEWTKDIDpmgtSKPQwmnpVVNDLATKMMTHINDAAATNALTLCATALLASRQRALSRDSLVSQINCYLSLL--KNVPY 561
Cdd:PRK03355 455 GPLTQDPD----AKRL----ALQKMAFEVAWRINQVTPVTATSLVSLLLLGTRGRALTLDELHHTLQDSLDYLerRQLPV 526
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 562 SAtfTVPKDSAEELVKHA---ESLNKFLIESDSMGD-IISLDRHQSILMTYYRNNIIHLFaLPSLIAQMTIR-----QRG 632
Cdd:PRK03355 527 ST--SALRLRDPEGVRAAldaLSNGGPVTRVDSGREpVWYIAPDDHLVAAFYRNSVIHAF-LERAIVELALAaaahvDEG 603
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 633 LSIDAIQENVATIYPFLKKELFLSyeeDKLEgVVSNIIEELVnqgmLVISDNEVTINQSNSQALMLLGRT---ISETLQR 709
Cdd:PRK03355 604 DRLAAFWDQAMRLRDLLKFEFFFA---DSDA-FRANLRAEMA----WIDPDWEDRLAAGGDEIDALLRAKrplMAHAMLR 675
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 880811188 710 -----YSIALNLLAENP--DLDKSDLEQKSQDIAQRLgRLQG-INAPEffdkGVFASMFATLKQ 765
Cdd:PRK03355 676 pffeaYEVVADVLRDAPpdTIDEKELTALALGLGRQY-VLQGrVRSSE----SVSTLLFATARQ 734
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
300-626 |
2.52e-35 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 144.63 E-value: 2.52e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 300 IVYVPCHRSHMDYLLLSYVLYHEGMVPPHIAAGINlnFFPAGPI---FRHGGAFFIRRSFKGNKLYSTIFREYLAELFAK 376
Cdd:PTZ00374 631 VVLLPLHRSYIDFIIMTYLLAVMGLPLPHVCAGDD--FLRMGPIatlMRGSGAFFMRRSFRDDPLYAALFKEYVRHLVLR 708
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 377 GYSVEYFSEGGRSRTGRLLQAKTGMLAMTIQAMLRGMNR--PVTLVPVYIGYEHVMEVATYAKELRGKRKEKENASLVIR 454
Cdd:PTZ00374 709 RRPLEFFIEGTRSRTGKTMAPKLGLLKFICDTFYEGQQEldDVLIIPVSLSYDELLETTLYAKEQLGVSKPKENPGNLLR 788
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 455 TiRKL--RNFGKGYVNFGEPIQLnQYLNEH----------------SPEWTKDIDPMGTSKPQWM-NPVVNDLATKMMTH 515
Cdd:PTZ00374 789 A-RSLlkRRHGKIHVHIGEPVSL-RSFKDHplqcplpfepkgeattSVCKTLDTTPSIARKSSITpPRVLTNIAWHLTHK 866
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 516 IND----------AAATNALTLCATAL-LASRQRALS--RDSLVSQiNCYLSLlknvpysatfTVPKDSAEELVKHA-ES 581
Cdd:PTZ00374 867 LQRntiitptalvAAVLECLGPTAGAMpLAEVQQGMTwlRTNIRRR-GAALSD----------DCANLNPETMVRKAlTH 935
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 880811188 582 LNKFLIESDSMGDIISL--DRHQSILMTYYRNNIIHLF---ALPSLIAQM 626
Cdd:PTZ00374 936 LQEFVEITDEMSEVIYVrqDVVTRLGVNICSNQLIHVFmdeAVVAVVARA 985
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
295-425 |
8.52e-32 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 120.46 E-value: 8.52e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 295 QDGHEIVYVPCHRSHMDYLLLSYVLYHEGmVPPHIAAGINLNFFP-AGPIFRHGGAFFIRRsfkGNKLYSTIFREYLAEL 373
Cdd:pfam01553 11 PRGGPAIVVANHQSYLDVLLLSLALYKRG-RPLVFVAKKELFDIPlVGWLMRLLGCIFIDR---KNRKDAAGTLEYLVEL 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 880811188 374 FAKGYSVEYFSEGGRSRTGRLLQAKTGMLAMTIQAmlrgmnrPVTLVPVYIG 425
Cdd:pfam01553 87 LREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEA-------GVPIVPVAIS 131
|
|
| PRK11915 |
PRK11915 |
lysophospholipid acyltransferase; |
306-549 |
6.53e-28 |
|
lysophospholipid acyltransferase;
Pssm-ID: 237022 [Multi-domain] Cd Length: 621 Bit Score: 119.66 E-value: 6.53e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 306 HRSHMDYLLLSYVLYHEGMVPPHIAAGINLNFFPAGPIFRHGGAFFIRRSFKGNKLYSTIFREYLAELFAKGYSVEYFSE 385
Cdd:PRK11915 123 HRSYLDGMLLPEVILANRLSPALTFGGANLNFFPMGAWAKRTGAIFIRRQTKDIPVYRFVLRAYAAQLVQNHVNLTWSIE 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 386 GGRSRTGRLLQAKTGMLAMTIQAMLRGMNRPVTLVPVYIGYEHVMEVATYAKELRGKRKEKENASLVIRTIRKL-RNFGK 464
Cdd:PRK11915 203 GGRTRTGKLRPPVFGILRYITDAVDEIDGPEVYLVPTSIVYDQLHEVEAMTTEAYGAVKRPEDLRFLVRLARQQgERLGR 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 465 GYVNFGEPIQLNQYLNEHSPewtkdiDPMGTSKpqwmnpVVNDLATKMMTHINDAAATNALTLCATALLASrQRALSRDS 544
Cdd:PRK11915 283 AYLDFGEPLPLRKRLQELRA------DKSGTGS------EIERIALDVEHRINRATPVTPTAVVSLALLGA-DRSLSISE 349
|
....*
gi 880811188 545 LVSQI 549
Cdd:PRK11915 350 VLATV 354
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
300-426 |
1.05e-25 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 102.43 E-value: 1.05e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 300 IVYVPCHRSHMDYLLLSYVLYHEGMVPPHIAAGINLNFFPAGPIFRHGGAFFIRRSFKgnKLYSTIFREYLaELFAKGYS 379
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNG--RKARAALREAV-ELLKEGEW 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 880811188 380 VEYFSEGGRSRTGRLLQAKTGMLAMTIQAmlrgmnrPVTLVPVYIGY 426
Cdd:smart00563 78 LLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRG 117
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
435-744 |
9.34e-18 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 86.03 E-value: 9.34e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 435 YAKELRGKRKEKENASLVIRTIRKL--RNFGKGYVNFGEPIQLNQYLNEHspewtkdiDPMGTSKPQWMNPVVNDLATKM 512
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSYARSQlsLKLGRVYVRFGEPWSLREFLDEQ--------GDRPATDAARRRLALQKLAFEV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 513 MTHINDAAATNALTLCATALLASRQRALSRDSLVSQINCYLSLL--KNVPYSATFTVPKD----------SAEELVKHAE 580
Cdd:pfam19277 73 LSRINRVTPVMPTALVGTVLLTLRGRALTLSELIRRVEWLLDYIraRGGPVAHFGDLRTEevvdraldvlGNAGLVTRVD 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 581 SLNK--FLIESDsmgdiislDRHQsilMTYYRNNIIHLFALPSLI-----AQMTIRQRGLSIDAIQENVATIYPFLKKEL 653
Cdd:pfam19277 153 GGPEpvYYIAPE--------DHFQ---ASFYRNMTIHLFVERAIVelallTKVKAAQRGDSYEALWDQVLRLRDLLKFEF 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 654 FLSyeeDKlEGVVSNIIEEL---VNQGMLVISDNEVTINQSNSQALMLLGRTISETLQRYSIALNLLAE---NPDLDKSD 727
Cdd:pfam19277 222 FFP---PK-EGFRENLRAELdllDPWEDRVITGERDIERLLGRENPDFACFLLWPFIEAYWLVADSLADltpDAWIDEKD 297
|
330 340
....*....|....*....|
gi 880811188 728 LeqksQDIAQRLGR---LQG 744
Cdd:pfam19277 298 F----QDEALGLGKqlyLQG 313
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
301-490 |
3.14e-17 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 81.21 E-value: 3.14e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 301 VYVPCHRSHMDYLLLSYVLYHegmvPPHIAAGINLNFFP-AGPIFRHGGAFFIRRSfKGNKLYSTIfrEYLAELFAKGYS 379
Cdd:COG0204 46 LIVANHQSWLDILLLLAALPR----PVRFVAKKELFKIPlLGWLLRALGAIPVDRS-KRRAALRAL--RQAVEALKAGES 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 380 VEYFSEGGRSRTGRLLQAKTGMLAMTIQAmlrgmnrPVTLVPVYIGYEHvmevatyakelrgkrkekenaslVIRTIRKL 459
Cdd:COG0204 119 LVIFPEGTRSPDGRLLPFKTGAARLALEA-------GVPIVPVAIDGTE-----------------------RALPKGFL 168
|
170 180 190
....*....|....*....|....*....|.
gi 880811188 460 RNFGKGYVNFGEPIQLNQYLNEHSPEWTKDI 490
Cdd:COG0204 169 PRPGKVTVRIGPPIDPSDLEGEDRRELAERL 199
|
|
| LPLAT_AGPAT-like |
cd07989 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ... |
301-482 |
6.94e-14 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.
Pssm-ID: 153251 [Multi-domain] Cd Length: 184 Bit Score: 70.76 E-value: 6.94e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 301 VYVPCHRSHMDYLLLSYVLYHegmvPPHIAAGINLNFFP-AGPIFRHGGAFFIRRSfKGNKLYSTIfrEYLAELFAKGYS 379
Cdd:cd07989 27 IIVANHQSYLDPLVLGAALPR----PIRFVAKKELFKIPfLGWLLRLLGAIPIDRG-NGRSAREAL--REAIEALKEGES 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 380 VEYFSEGGRSRTGRLLQAKTGMLAMTIQAmlrgmnrPVTLVPVYIgyehvmevatyakelrgkrkekENASLVIRTIRKL 459
Cdd:cd07989 100 VVIFPEGTRSRDGELLPFKSGAFRLAKEA-------GVPIVPVAI----------------------SGTWGSLPKGKKL 150
|
170 180
....*....|....*....|...
gi 880811188 460 RNFGKGYVNFGEPIQLNQYLNEH 482
Cdd:cd07989 151 PRPGRVTVRIGEPIPPEGLELAE 173
|
|
| LPLAT |
cd06551 |
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ... |
295-427 |
7.17e-11 |
|
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).
Pssm-ID: 153244 [Multi-domain] Cd Length: 187 Bit Score: 62.05 E-value: 7.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 295 QDGHEIVYVPCHRSHMDYLLLSYVLYhEGMVPPHIAAGINLNFfPAGPIFRHGGAFFIRRSFKGNKLYSTifrEYLAELF 374
Cdd:cd06551 23 PGGGPVLFVSNHSSWWDGLILFLLLE-RGLRRDVYGLMDEELL-ERYPFFTRLGAFSVDRDSPRSAAKSL---KYVARLL 97
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 880811188 375 AKGYS-VEYFSEGGRSR-TGRLLQAKTGMLAMTIQAmlrgmnrPVTLVPVYIGYE 427
Cdd:cd06551 98 SKPGSvVWIFPEGTRTRrDKRPLQFKPGVAHLAEKA-------GVPIVPVALRYT 145
|
|
| LPLAT_AAK14816-like |
cd07992 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ... |
363-490 |
5.90e-03 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.
Pssm-ID: 153254 [Multi-domain] Cd Length: 203 Bit Score: 38.78 E-value: 5.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 880811188 363 STIFREyLAELFAKGYSVEYFSEGGrSRTG-RLLQAKTGMLAMTIQAmLRGMNRPVTLVPVYIGYEHvmevatyakelrg 441
Cdd:cd07992 97 AAVFDA-VGEALKAGGAIGIFPEGG-SHDRpRLLPLKAGAARMALEA-LEAGQKDVKIVPVGLNYED------------- 160
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 880811188 442 krKEKENASLVirtirklrnfgkgyVNFGEPIQLNQYLN-EHSPEWTKDI 490
Cdd:cd07992 161 --KSRFRSRVL--------------VEFGKPISVSAFEEaEASRDVEKKL 194
|
|
| |
