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Conserved domains on  [gi|895824484|ref|WP_048947141|]
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MULTISPECIES: pheromone response system RNA-binding regulator PrgU [Bacillota]

Protein Classification

PrgU domain-containing protein( domain architecture ID 10560333)

PrgU domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PrgU pfam09627
PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus ...
 5-107 1.15e-43

PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus bacteria. It forms a six beta-strand barrel with three accompanying alpha helices and is probably a homo-dimer in the cell. PrgU probably acts as a RNA-binding regulator that mitigates toxicity accompanying overproduction of PrgB-like adhesins, which are involved in conjugative transfer.


:

Pssm-ID: 462841  Cd Length: 105  Bit Score: 138.31  E-value: 1.15e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895824484    5 VAEREAKGMKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAMEMWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKSIY 84
Cdd:pfam09627   3 VVEREAKGTKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAEEIWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKSIY 82

                          90       100
                  ....*....|....*....|...
gi 895824484   85 VKPNLGKINVPVFFIKTPINRGV 107
Cdd:pfam09627  83 VKPNLGRINVPVFFIKTPINRGV 105
 
Name Accession Description Interval E-value
PrgU pfam09627
PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus ...
 5-107 1.15e-43

PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus bacteria. It forms a six beta-strand barrel with three accompanying alpha helices and is probably a homo-dimer in the cell. PrgU probably acts as a RNA-binding regulator that mitigates toxicity accompanying overproduction of PrgB-like adhesins, which are involved in conjugative transfer.


Pssm-ID: 462841  Cd Length: 105  Bit Score: 138.31  E-value: 1.15e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895824484    5 VAEREAKGMKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAMEMWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKSIY 84
Cdd:pfam09627   3 VVEREAKGTKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAEEIWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKSIY 82

                          90       100
                  ....*....|....*....|...
gi 895824484   85 VKPNLGKINVPVFFIKTPINRGV 107
Cdd:pfam09627  83 VKPNLGRINVPVFFIKTPINRGV 105
 
Name Accession Description Interval E-value
PrgU pfam09627
PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus ...
 5-107 1.15e-43

PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus bacteria. It forms a six beta-strand barrel with three accompanying alpha helices and is probably a homo-dimer in the cell. PrgU probably acts as a RNA-binding regulator that mitigates toxicity accompanying overproduction of PrgB-like adhesins, which are involved in conjugative transfer.


Pssm-ID: 462841  Cd Length: 105  Bit Score: 138.31  E-value: 1.15e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895824484    5 VAEREAKGMKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAMEMWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKSIY 84
Cdd:pfam09627   3 VVEREAKGTKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAEEIWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKSIY 82

                          90       100
                  ....*....|....*....|...
gi 895824484   85 VKPNLGKINVPVFFIKTPINRGV 107
Cdd:pfam09627  83 VKPNLGRINVPVFFIKTPINRGV 105
PrgU pfam09627
PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus ...
 14-117 4.34e-43

PrgU-like protein; PrgU is a protein of plasmid in origin expressed mainly in Enterococcus bacteria. It forms a six beta-strand barrel with three accompanying alpha helices and is probably a homo-dimer in the cell. PrgU probably acts as a RNA-binding regulator that mitigates toxicity accompanying overproduction of PrgB-like adhesins, which are involved in conjugative transfer.


Pssm-ID: 462841  Cd Length: 105  Bit Score: 136.77  E-value: 4.34e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895824484   14 KEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAMEMWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKSIYVKPNLGKIN 93
Cdd:pfam09627   1 KEVVEREAKGTKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAEEIWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKS 80

                          90       100
                  ....*....|....*....|....
gi 895824484   94 VPVFFIKTPINRGVFEEIFGETLK 117
Cdd:pfam09627  81 IYVKPNLGRINVPVFFIKTPINRG 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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