|
Name |
Accession |
Description |
Interval |
E-value |
| PQQ_membr_DH |
TIGR03074 |
membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; This protein ... |
35-790 |
0e+00 |
|
membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Members of this family have several predicted transmembrane helices in the N-terminal region, and include the quinoprotein glucose dehydrogenase (EC 1.1.5.2) of Escherichia coli and the quinate/shikimate dehydrogenase of Acinetobacter sp. ADP1 (EC 1.1.99.25). Sequences closely related except for the absense of the N-terminal hydrophobic region, scoring in the gray zone between the trusted and noise cutoffs, include PQQ-dependent glycerol (EC 1.1.99.22) and and other polyol (sugar alcohol) dehydrogenases.
Pssm-ID: 274418 [Multi-domain] Cd Length: 764 Bit Score: 1125.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 35 KLATVGGSSYFLIMGVAMVIAAILIFLNRISGIVLYGIAFIASLFWAVSDAGWDFWPLFSRLFTFTVLAFLCAIvwPFLR 114
Cdd:TIGR03074 1 WLVALGGSWYYLLAGLALLLSAWLLFRRRPAGLWLYAALLLGTLIWALWEVGLDFWPLIPRLGLIAVLGLWLLL--PWVR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 115 AANHTAPNKAPAFGVAALLAVAMLVSLGWMF-KPQTLVAA--NEPVPVKPVAPGEQQKNWEHWGNTTHGDRFAALDQINK 191
Cdd:TIGR03074 79 RPRSVGPARRGAGALAGVLAVAVLAALASMFtDPHPIVGAldTEVPATAAAAPAVPAGDWAAYGRTQAGQRYSPLDQINP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 192 QNVSSLKVAWVAHTGDIPQSNGSG-AEDQNTPLQIGDTLYVCTPYSKVLALDVDSGKEKWRYDSKATA---PNWQRCRGL 267
Cdd:TIGR03074 159 DNVGNLKVAWTYHTGDLKTPDDPGeATFQATPLKVGDTLYLCTPHNKVIALDAATGKEKWKFDPKLKTeadRQHQTCRGV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 268 GYFEDHSTVTTSQAETQPAACPRRLFLPTTDARLIAINADNGKVCDDFGDHGTVDLSVGMGEIKPGYYQQTSTPLVAGNV 347
Cdd:TIGR03074 239 SYYDAPAAAAGPAGPAAPADCARRIILPTSDARLIALDADTGKLCEDFGNNGTVDLTAGMGPTPPGYYYPTSPPLVAGTT 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 348 VVVGGRVADNYSTGEPPGVVRAYDVHTGKLAWAWDPGNPNLTGLPPEGQTYTRGTPNVWSAMSYDAKLNLIYLPTGNATP 427
Cdd:TIGR03074 319 VVIGGRVADNYSTDEPSGVIRAFDVNTGALVWAWDPGNPDPTAPPAPGETYTRNSPNSWSVASYDEKLGLVYLPMGNQTP 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 428 DFWAGERTALDDKYSSSIVAVDAATGQVRWHFQTTHHDLWDFDLPSQPLLYDLPDGKGGTTPVLVQTSKQGMIFMLNRET 507
Cdd:TIGR03074 399 DQWGGDRTPADEKYSSSLVALDATTGKERWVFQTVHHDLWDMDVPAQPSLVDLPKADGTTVPALVAPTKQGQIYVLDRRT 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 508 GKPVAKVEERPVPAGNVEGERYSPTQPYSIgmPMIGNQTLTESDMWGATPVDLLLCRIQFKEMRHQGVFTPPGLDRSLQF 587
Cdd:TIGR03074 479 GEPIVPVEEVPVPQGAVPGERYSPTQPFSV--LTFGPPTLTESDMWGATPFDQLACRIQFKSLRYEGLYTPPSEQGSLVF 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 588 PGSLGGMNWGSVSVDPNNSLMFVNDMRLGLANYMVPRANVAK-----DASGIEMGIVPMDGTPFGAMRERFLSPLGIPCQ 662
Cdd:TIGR03074 557 PGNLGGFNWGGVAVDPTRQVMFVNPMRLPFVSQLVPRAPGDEapsgaKGKGTEMGLNPNKGTPYAVNMNPFLSPLGIPCQ 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 663 KPPFGTMSAVDLKTGKLVWQVPVGTVEDTGPLGIRMHMPIPIGMPTLGASLSTQSGLLFFAGTQDFYLRAFDTATGKEIW 742
Cdd:TIGR03074 637 APPWGYMAAIDLKTGKVVWQHPNGTVRDTGPMGIPMPLPIPIGVPTLGGPLATAGGLVFIGATQDNYLRAYDLSTGKELW 716
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 895847355 743 KDRLPVGSQSGPMTYVsPKTGKQYILINAGGARQS-PDRGDYVIAYALP 790
Cdd:TIGR03074 717 EARLPAGGQATPMTYM-GKDGKQYVVIVAGGHGSSgTKRGDYVIAYALP 764
|
|
| PQQ_mGDH |
cd10280 |
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes ... |
171-789 |
0e+00 |
|
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes belongs to the dehydrogenase family with pyrroloquinoline quinone (PQQ) as cofactor, and is the only subfamily that is bound to the membrane. Glucose dehydrogenase converts D-glucose to D-glucono-1,5-lactone in a reaction that is coupled with the respiratory chain in the periplasmic oxidation of sugars and alcohols in gram-negative bacteria. Ubiquinone functions as the electron acceptor. The alignment model contains an 8-bladed beta-propeller.
Pssm-ID: 199838 [Multi-domain] Cd Length: 616 Bit Score: 925.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 171 WEHWGNTTHGDRFAALDQINKQNVSSLKVAWVAHTGDIPQSNGSGAEDQNTPLQIGDTLYVCTPYSKVLALDVDSGKEKW 250
Cdd:cd10280 1 WPAYGGDPGGTRYSPLDQITPDNVGKLKVAWTYHTGDLPGPDGNEGTFEATPLKVGGTLYLCTPHNRVIALDAATGKELW 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 251 RYDSKATA---PNWQRCRGLGYFEDhstvttsqaETQPAACPRRLFLPTTDARLIAINADNGKVCDDFGDHGTVDLSVGM 327
Cdd:cd10280 81 RFDPKAGAdaaPGHQTCRGVSYWED---------GAAAAACARRIFFGTGDARLIALDARTGKPCPDFGDNGVVDLREGL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 328 GEIKPGYYQQTSTPLVAGNVVVVGGRVADNYSTGEPPGVVRAYDVHTGKLAWAWDPGNPNLT-GLPPEGQTYTRGTPNVW 406
Cdd:cd10280 152 GRVKPGFYSSTSPPTVYGDLVIVGSAVADNQAVDAPSGVIRAFDVRTGKLVWAFDTIPPPGEaGPDTAGAWYTRGGPNVW 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 407 SAMSYDAKLNLIYLPTGNATPDFWAGERTAlDDKYSSSIVAVDAATGQVRWHFQTTHHDLWDFDLPSQPLLYDLPdGKGG 486
Cdd:cd10280 232 AGMSADEKLGLVYLPTGSATPDFYGGDRPG-DNLFANSLVALDAATGKRRWHFQTVHHDLWDYDLPAQPTLVDVP-RDGK 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 487 TTPVLVQTSKQGMIFMLNRETGKPVAKVEERPVPAGNVEGERYSPTQPYSIGMPMIGNQTLTESDMWGATPVDLLLCRIQ 566
Cdd:cd10280 310 TVPAVAQPTKQGFVFVLDRRTGKPLWPVEERPVPQGDVPGERTSPTQPFPTLPPPFARQGLTEDDMWGATPFDQLACRIQ 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 567 FKEMRHQGVFTPPGLDRSLQFPGSLGGMNWGSVSVDPNNSLMFVNDMRLGLANYMVPRANVAKDASGIEM-------GIV 639
Cdd:cd10280 390 FRSLRYEGLFTPPSLDGTLIFPGNDGGANWGGAAVDPERGILYVNSNRLPFVIQLVPRAPGDPAGVAGGGeggggggGPS 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 640 PMDGTPFGAMRERFLSPLGIPCQKPPFGTMSAVDLKTGKLVWQVPVGTVEDTGPLGIrmHMPIPIGMPTLGASLSTQSGL 719
Cdd:cd10280 470 PQAGTPYGVGRGRFLSPLGLPCQAPPWGTLTAIDLNTGKILWQVPLGTVPDLGPKGI--PLPIPTGTPNLGGPVVTAGGL 547
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 895847355 720 LFFAGTQDFYLRAFDTATGKEIWKDRLPVGSQSGPMTYVSpkTGKQYILINAGGARQ-SPDRGDYVIAYAL 789
Cdd:cd10280 548 VFIAATQDNYLRAFDKATGKELWEARLPAGGQATPMTYEV--DGKQYVVIAAGGHGSlGTKRGDSVIAYAL 616
|
|
| Gcd |
COG4993 |
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism]; |
168-790 |
0e+00 |
|
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
Pssm-ID: 444017 [Multi-domain] Cd Length: 515 Bit Score: 598.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 168 QKNWEHWGNTTHGDRFAALDQINKQNVSSLKVAWVAHTGDIPQSngsgaEDQNTPLQIGDTLYVCTPYSKVLALDVDSGK 247
Cdd:COG4993 2 PGDWLAYGGDYAGQRYSPLDQINPDNVKKLKVAWTFSTGDLPER-----GHEATPLVVDGVLYVCTPHNRVFALDAATGK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 248 EKWRYDSK---ATAPNWQRCRGLGYFEDhstvttsqaetqpaacprRLFLPTTDARLIAINADNGKVCDDfgdHGTVDLS 324
Cdd:COG4993 77 ELWRYDPKlpdDAACCDVVNRGVAYYDG------------------RIFLGTLDGRLVALDAKTGKVCWD---VKVGDPK 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 325 VGmgeikpgyYQQTSTPLVAGNVVVVGGRVADNystgEPPGVVRAYDVHTGKLAWAWDPG-NPNLTGL--PPEGQTYTRG 401
Cdd:COG4993 136 KG--------YTITSAPLVVKDKVIVGGSGGEF----GPRGVVRAYDARTGKLVWRFDTIpDPGEPGAetWPPGDTWKRG 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 402 TPNVWSAMSYDAKLNLIYLPTGNATPDFWAGERtALDDKYSSSIVAVDAATGQVRWHFQTTHHDLWDFDLPSQPLLYDLP 481
Cdd:COG4993 204 GGNVWGTMSYDPELGLVYLPTGNPAPDWNGGQR-PGDNLYSSSIVALDADTGELKWHYQTVPHDLWDYDGPNEPILVDLP 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 482 DGkGGTTPVLVQTSKQGMIFMLNRETGKPVAkveerpvpagnvegeryspTQPYSIGMPMIgnqtlTESDMWGATPvdll 561
Cdd:COG4993 283 VD-GKTRKALVQATKNGFIYVLDRETGEPLV-------------------TQPFVKPPNWA-----TEIDMWGATP---- 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 562 lcriqfkemrhqgVFTPPGLD--RSLQFPGSLGGMNWGSVSVDPNNSLMFVNDMRLGLANYMVPRAnvakdasgiemgiv 639
Cdd:COG4993 334 -------------IQTPPSLDgkTTLICPGALGGKNWGPAAYDPETGLLYVPANELCMDYELVPRE-------------- 386
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 640 PMDGTPF-GAMRERFlsplgiPCQKPPFGTMSAVDLKTGKLVWQVPVgtvedtgplgirmhmpipiGMPTLGASLSTQSG 718
Cdd:COG4993 387 YQAGAPYlGATLTMY------PCPAPPWGTLTAIDLNTGKIVWQVPL-------------------GFPNWGGPLATAGG 441
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 895847355 719 LLfFAGTQDFYLRAFDTATGKEIWKDRLPVGSQSGPMTYVspKTGKQYILINAGGARQSP-----DRGDYVIAYALP 790
Cdd:COG4993 442 LV-FIGTLDGYLRAFDAKTGKELWKFRLPSGGQATPMTYE--VDGKQYVAVAAGGGGWLGlglytPQGDYLIAFALP 515
|
|
| PQQ_enz_alc_DH |
TIGR03075 |
PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic ... |
169-772 |
2.41e-75 |
|
PQQ-dependent dehydrogenase, methanol/ethanol family; This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Genes in this family often are found adjacent to the PQQ biosynthesis genes themselves. An unusual, strained disulfide bond between adjacent Cys residues contributes to PQQ-binding, as does a Trp residue that is part of a PQQ enzyme repeat (see pfam01011). Characterized members include the dehydrogenase subunit of a membrane-anchored, three subunit alcohol (ethanol) dehydrogenase of Gluconobacter suboxydans, a homodimeric ethanol dehydrogenase in Pseudomonas aeruginosa, and the large subunit of an alpha2/beta2 heterotetrameric methanol dehydrogenase in Methylobacterium extorquens.
Pssm-ID: 274419 [Multi-domain] Cd Length: 527 Bit Score: 254.14 E-value: 2.41e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 169 KNWEHWGNTTHGDRFAALDQINKQNVSSLKVAWVAHTGDIpqsngSGAEDQntPLQIGDTLYVCTPYSKVLALDVDSGKE 248
Cdd:TIGR03075 19 SDWLTYGGGYAGQRYSPLDQINTDNVKKLQPAWTFSLGKQ-----RGQESQ--PLVVDGVMYVTTSYSRVYALDAKTGKI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 249 KWRYDSK---ATAPnwQRC-----RGLGYFEDhstvttsqaetqpaacprRLFLPTTDARLIAINADNGKVC--DDFGDH 318
Cdd:TIGR03075 92 LWKYDPKlpdDIIP--VMCcdvvnRGAALYDG------------------KVFFGTLDARLVALDAKTGKVVwsKKNGDY 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 319 gtvdlsvgmgeiKPGYYQqTSTPLVAGNVVVVGGrvadnySTGE--PPGVVRAYDVHTGKLAWAW-----DPGNPNLTGL 391
Cdd:TIGR03075 152 ------------KKGYTI-TAAPLVVKGKVITGI------SGGEfgVRGYVTAYDAKTGKLVWRRytvpgDMGYLKKTGK 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 392 PP---------EGQTYTRGTPNVWSAMSYDAKLNLIYLPTGNATPdfWAGERTALDDKYSSSIVAVDAATGQVRWHFQTT 462
Cdd:TIGR03075 213 PVggdpgaktwPGDAWKTGGGATWGTGSYDPETNLIYFGTGNPAP--WNSHLRPGDNLYTSSIVARDPDTGKIKWHYQTT 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 463 HHDLWDFDLPSQPLLYDLP-DGKggTTPVLVQTSKQGMIFMLNRETGKPVAkveerpvpagnveGERYSPTQPYSIGMPM 541
Cdd:TIGR03075 291 PHDEWDYDGVNEMILFDLKkDGK--PRKLLAHADRNGFFYVLDRTNGKLLS-------------AEPFVDKVNWATGVDL 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 542 IGNQTLTESDMWGATPVDlllcriqfkemrHQGVFtppgldrslQFPGSLGGMNWGSVSVDPNNSLMFV--NDMRLGLAN 619
Cdd:TIGR03075 356 KTGRPIEVPEARSTDGKK------------GKPVE---------VCPGFLGGKNWQPMAYSPKTGLFYVpaNHVCMDYWP 414
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 620 YMVP----RANVakdasGIEMGIVPMDGTPFGAMRerflsplgipcqkppfgtmsAVDLKTGKLVWQVPvgtvEDtgplg 695
Cdd:TIGR03075 415 EKVSykkgAAYL-----GAGFTIKPPPDDHIGSLI--------------------AWDPITGKIVWEHK----ED----- 460
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 895847355 696 irmhmpipigMPTLGASLSTqSGLLFFAGTQDFYLRAFDTATGKEIWKDRLPVGSQSGPMTYVspKTGKQYILINAG 772
Cdd:TIGR03075 461 ----------FPLWGGVLAT-AGDLVFTGTLEGYFKAFDAKTGEELWKFKTGSGIVGPPVTYE--QDGKQYVAVLSG 524
|
|
| PQQ_ADH_I |
cd10277 |
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ... |
169-772 |
1.78e-74 |
|
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.
Pssm-ID: 199835 [Multi-domain] Cd Length: 529 Bit Score: 251.83 E-value: 1.78e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 169 KNWEHWGNTTHGDRFAALDQINKQNVSSLKVAWVAHTGDIPQsngsGAEDQntPLQIGDTLYVCTPYSKVLALDVDSGKE 248
Cdd:cd10277 9 GNWLTYGRGYNGQRYSPLKQINTDNVKNLVPAWSFSFGGKQR----GQESQ--PIVNDGVMYVTTSYNRVFAIDAKTGKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 249 KWRYDSKATAPNWQRC----RGLGYFEDhstvttsqaetqpaacprRLFLPTTDARLIAINADNGKVCDDfgdhgtvdls 324
Cdd:cd10277 83 LWKYKHRLPEDIRPCCdvvnRGVALYGD------------------KVYFGTLDAHLVALDAKTGKVVWK---------- 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 325 VGMGEIKPGYYQqTSTPLVAGNVVVVGGrvadnySTGE--PPGVVRAYDVHTGKLAWAW-------DPGNPNltglPPEG 395
Cdd:cd10277 135 KKVADYKAGYSM-TLAPLVVKGKVIVGV------SGGEfgVRGFIAALDAETGKEVWRTytvpgpgEPGSTD----TWPG 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 396 QTYTRGTPNVWSAMSYDAKLNLIYLPTGNATPDfWAGERTAlDDKYSSSIVAVDAATGQVRWHFQTTHHDLWDFDLPSQP 475
Cdd:cd10277 204 DAWKTGGGATWLTGTYDPETNLLYWGVGNPAPW-NGDLRPG-DNLYTSSVLALDPDTGKIKWHYQYTPNDTWDYDGVNEP 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 476 LLYDLPDgKGGTTPVLVQTSKQGMIFMLNRETGKPVAkveerpvpagnvegerysptqpysiGMPMIGNQTLTESDMWGA 555
Cdd:cd10277 282 VLFDYTK-NGKPVKALVHADRNGFFYVLDRTNGKLIW-------------------------ATPFVKKITWASIDLKTG 335
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 556 TPVDlllcriqfKEMRhqgvfTPPGLDRSLQF-PGSLGGMNWGSVSVDPNNSLMFvndmrlglanymVPRANVAKDASGI 634
Cdd:cd10277 336 RPIY--------DEDK-----VPPKKGKTVDFcPSFLGGKNWPPMAYSPDTGLFY------------VPANHWCMDLTGE 390
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 635 EMGIVPmdGTPFGAMrerflSPLGIPCQKPPFGTMSAVDLKTGKLVWQVPVGTvedtgplgirmhmpipigmPTLGASLS 714
Cdd:cd10277 391 PVSYKK--GAAYLGA-----GFTIKPPFEDHIGELQAIDPTTGKKVWEHKTPL-------------------PLWGGVLT 444
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 895847355 715 TQSGLLfFAGTQDFYLRAFDTATGKEIWKDRLPVGSQSGPMTYvsPKTGKQYILINAG 772
Cdd:cd10277 445 TAGGLV-FTGTPDGYFRAFDAKTGKELWEFQTGSGIIGPPVTW--EVDGKQYVAVLSG 499
|
|
| PQQ_DH_like |
cd00216 |
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases ... |
191-773 |
4.21e-72 |
|
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases with pyrroloquinoline quinone (PQQ) as a cofactor, such as ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller, and the family also includes distantly related proteins which are not enzymatically active and do not bind PQQ.
Pssm-ID: 199833 [Multi-domain] Cd Length: 434 Bit Score: 242.51 E-value: 4.21e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 191 KQNVSSLKVAWVAHTGDIPQsNGSGAedqnTPLQIGDTLYVCTPYSKVLALDVDSGKEKWRYDSKATaPNWQR------C 264
Cdd:cd00216 1 ADNVFQLTPAWSFSTGDGGN-RGSEL----TPIVVDGVMYATTSFSRVFALDADDGKEIWSYDPALK-DGWFEaccdlvN 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 265 RGLGYFEDHstvttsqaetqpaacprrLFLPTTDARLIAINADNGKVCD--DFGDHGtvdlsvgmgeikpGYYQQTSTPL 342
Cdd:cd00216 75 RGVAVWGGK------------------VYIGVLDGRVYALNAETGKVAWkvKNADVL-------------GGYTATSAPV 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 343 VAGNVVVVGGRVaDNYSTgepPGVVRAYDVHTGKLAWAWDPGNPNLTGLPP-------------EGQTYTRGTPNVWSAM 409
Cdd:cd00216 124 VVDGLVIIGSSG-DEFGV---RGYLTAYDVATGEEKWRFYLVMPDPNLLPGkdstvtdrntptgDEHTWTSGGGTGWSSA 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 410 SYDAKLNLIYLPTGNATPDFWAGERTALDDKYSSSIVAVDAATGQVRWHFQTTHHDLWDFDLPSQPLLYDLPDgKGGTTP 489
Cdd:cd00216 200 AYDAELNLIYVGGGNPTPWNWGGNRTPGDNLYTSSIVAVNADTGEMKWQYQTTPHDAWDYDGDNTPVLADIKV-KGKKVK 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 490 VLVQTSKQGMIFMLNRETGKpvakveerpvpagnvegerysptqpysigmpmignqtltesdmwgatpvdlllcriqfke 569
Cdd:cd00216 279 VLFAPAKNGNFYVLDRRNGE------------------------------------------------------------ 298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 570 mrhqgvftppgldrsLQFPGSLGGMnwgsvSVDPNNSLMFVndmrlglanymvpranvakdasgiemgivpmdgtpfgam 649
Cdd:cd00216 299 ---------------LVSARPLVPD-----SYDPDRELFYV--------------------------------------- 319
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 650 rerflsplgipcqkPPFGTMSAVDLKTGKLVWQVpvgtvedtgplgirmhmpiPIGMPTLGASLSTQSGLLFFaGTQDFY 729
Cdd:cd00216 320 --------------PANGRIMALDPVTGVVVWEK-------------------SELHPLLGGPLSTAGNLVFV-GTSDGY 365
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 895847355 730 LRAFDTATGKEIWKDRLPVGSQSGPMTYvsPKTGKQYILINAGG 773
Cdd:cd00216 366 LKAYNADTGEKLWQQKVPSGFQAEPVTY--EVDGEQYVLIQAGG 407
|
|
| PQQ_ADH_II |
cd10279 |
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of ... |
170-772 |
3.52e-63 |
|
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of monomeric and soluble type II alcohol dehydrogenases utilizes pyrroloquinoline quinone (PQQ) as a cofactor and is related to ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller.
Pssm-ID: 199837 [Multi-domain] Cd Length: 549 Bit Score: 221.36 E-value: 3.52e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 170 NWEHWGNTTHGDRFAALDQINKQNVSSLKVAWVAhtgDIPQSNGSGAedqnTPLQIGDTLYVCTPYSKVLALDVDSGKEK 249
Cdd:cd10279 2 NWLSYGRDYDEQRFSPLTQINRSNVGQLGLAWYF---DLDTNRGQEA----TPLVVDGVMYVSGPWSVVYALDARTGKLL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 250 WRYDSKAtAPNWQR---C----RGLGYFEDhstvttsqaetqpaacprRLFLPTTDARLIAINADNGKV------CDDfg 316
Cdd:cd10279 75 WQYDPEV-DRESGRkacCdvvnRGVAVWDG------------------KVFVGTLDGRLIALDAKTGKEvwsvdtIDP-- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 317 dhgtvdlsvgmgeiKPGYYqqtstplvagnvvvvggrvadnySTGEPP------------------GVVRAYDVHTGKLA 378
Cdd:cd10279 134 --------------RKPYT-----------------------ITGAPRvakgkvvignggaefgvrGYVSAYDAETGKLV 176
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 379 WAWD--PGNPNLTGLPPEGQ-----------TYTRGTPNVWSAMSYDAKLNLIYLPTGNATP-DFWAGERTALDDKYSSS 444
Cdd:cd10279 177 WRFYtvPGNPAKPFEHASLEaaaatwwtgewWRTGGGGTVWDSITYDPELDLLYIGTGNGSPwNRKVRSPGGGDNLFLSS 256
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 445 IVAVDAATGQVRWHFQTTHHDLWDFDlPSQPL-LYDLP-DGKggTTPVLVQTSKQGMIFMLNRETGKPVAkveerpvpag 522
Cdd:cd10279 257 IVALDADTGRYKWHYQTTPGDTWDYT-ATQPIiLADLEiDGK--PRKVLMHAPKNGFFYVLDRATGKLLS---------- 323
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 523 nveGERYSPTQpysigmpmignqtltesdmWgATPVDLLLCR-IQFKEMRHQgvftppgLDRSLQFPGSLGGMNWGSVSV 601
Cdd:cd10279 324 ---AEPFVPVN-------------------W-ATGIDLKTGRpIENPEARYT-------KGPKLVFPGPLGAHNWHPMSY 373
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 602 DPNNSLMF--VNDMRLGLANYMV-PRANVAKDASGIEMGIVPMDGTPFGAMRerflsplgipcqKPPFGTMSAVDLKTGK 678
Cdd:cd10279 374 NPDTGLVYipAQEIPAVYEDDPGdFGYNPLGWNTGITPDATPPPAAAKRALR------------KATRGRLVAWDPVTQK 441
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 679 LVWQVPvgtvedtgplgirmhMPIPIGmptlGASLSTQSGLLfFAGTQDFYLRAFDTATGKEIWKdrLPVGSQ--SGPMT 756
Cdd:cd10279 442 AAWRVE---------------HPGPWN----GGVLATAGNLV-FQGTADGELAAYDARTGEKLWS--FDTGSGivAAPMT 499
|
650
....*....|....*..
gi 895847355 757 Y-VSpktGKQYILINAG 772
Cdd:cd10279 500 YsVD---GEQYVAVLAG 513
|
|
| PQQ_MDH |
cd10278 |
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ... |
171-772 |
5.14e-62 |
|
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.
Pssm-ID: 199836 [Multi-domain] Cd Length: 553 Bit Score: 218.35 E-value: 5.14e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 171 WEHWGNTTHGDRFAALDQINKQNVSSLKVAWVAHTGDIPQSNGSgaedqntPLQIGDTLYVCTPY-SKVLALDV-DSGKE 248
Cdd:cd10278 1 WVMPGKDYANTRYSPLAQINKDNVKNLKVAWTFSTGVLRGHEGA-------PLVVGDTMYVVTPFpNNVYALDLnDPGKI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 249 KWRYDSKaTAPNWQ--RC-----RGLGYFedhstvttsqaetqpaacPRRLFLPTTDARLIAINADNGKVCddfgdhgtv 321
Cdd:cd10278 74 LWKYKPK-QDPSAVavACcdvvnRGLAYA------------------DGKIFFNQLDGHLVALDAKTGKEV--------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 322 dLSVGMGEIKPGyyqQTST--PLVAGNVVVVGgrvadnySTGEPPGV---VRAYDVHTGKLAW-AWDPG----------- 384
Cdd:cd10278 126 -WKVKNGDPKVG---ETLTmaPLVVKDKVIVG-------ISGGEFGVrgyVTAYDLKTGKLVWrAYSTGpdkdvligpdf 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 385 NPNLT-------GLPP-EGQTYTRGTPNVWSAMSYDAKLNLIYLPTGNatPDFWAGERTALDDKYSSSIVAVDAATGQVR 456
Cdd:cd10278 195 NPFNPhdggkdlGLSTwPGDAWKIGGGTNWGWYSYDPKLNLVYYGTGN--PGPWNPTQRPGDNKWSMTIFARDPDTGEAK 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 457 WHFQTTHHDLWDFDLPSQPLLYDLP-DGKGgtTPVLVQTSKQGMIFMLNRETGKPVakVEERPVPAGNVEGerysptqpy 535
Cdd:cd10278 273 WAYQMTPHDEWDYDGVNEMILVDQTvDGKK--RKLLVHFDRNGFVYTLDRTTGELL--SAEKFDPVNNWKG--------- 339
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 536 sigmpmignqtltesdmwgatpVDLLLCRIQfKEMRHqgvftPPGLDRSLQ--FPGSLGGMNWGSVSVDPNNSLMFvndm 613
Cdd:cd10278 340 ----------------------VDLKTGRPV-KDPEK-----STHMDHNVTdiCPSAMGGKDQQPSSYSPKTGLFY---- 387
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 614 rlglanymVPRANVAKDASGIEMGIVPmdGTPF-GAMRERFLSPLGIpcqkppFGTMSAVDLKTGKLVWQvpvgtvedtg 692
Cdd:cd10278 388 --------VPTNHLCMDYEPFEVNYTA--GQPYvGATLAMYPGPGGH------MGQFKAWDPVTGKTKWE---------- 441
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 693 plgirmhmpIPIGMPTLGASLSTQSGLLFFaGTQDFYLRAFDTATGKEIWKDRLPVGSQSGPMTYVSpkTGKQYILINAG 772
Cdd:cd10278 442 ---------IKERFPVWSGTLATAGGLVFY-GTLDGWFKAVDAKTGKLLWKFKLPSGIIGNPITYKH--DGKQYVAVLSG 509
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
193-515 |
1.96e-09 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 60.04 E-value: 1.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 193 NVSSLKVAWVAHTGdipqsNGSGAEDQNTPLQIGDTLYVCTPYSKVLALDVDSGKEKWRYDSKATAPNWQrcrGLGYFED 272
Cdd:cd10276 10 PEFDPEVLWSKSVG-----NGGMAGIDLTPVVAGDMVYAADANGQVSAFNATTGKIIWETSLSGKGFLGG---TPAVGNG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 273 H-----------------------STVTTSQAETQPAACPRRLFLPTTDARLIAINADNGKVCdDFGDHGTVDLSVGMGe 329
Cdd:cd10276 82 KifvgtesgylyaldakdgselwrTEVSDSQLLSPPTYADGKIYVGTGDGRLYYCNAETGKVV-WNRTSTAPELSLRGG- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 330 ikpgyyqqtSTPLvagnvvvvggRVADNYSTGEPPGVVRAYDVHTGKLAWAWDPGNPN----LTGLPPEGQTYTRGTPNV 405
Cdd:cd10276 160 ---------AAPV----------GAYDVVFVGDGNGTVVALNTGTGVDIWEFSVSEPRgrteLPRMIDSSVTYVVVGGYL 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 406 WSAmSYDAKLNLIYLPTGNAtpdFWAGER-----TALDDKYS-------SSIVAVDAATGQVRWHFQTTHHdlwdfDLPS 473
Cdd:cd10276 221 YST-SYQGYLVALDFESGQF---LWSRKAsggtsTSTDANGRvyvgdgeGSLYCLDASTGDELWSQTVLLG-----RVLS 291
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 895847355 474 QPLLYDLPDgkggttpVLVQTSKQGMIFMLNRETGKPVAKVE 515
Cdd:cd10276 292 SPAIYVGVY-------IYVTDNAEGYLYCLKDNDGLTVARVE 326
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
196-457 |
8.75e-06 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 48.66 E-value: 8.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 196 SLKVAWVAHTGDipqsngsGAEDQNTPLQI---GDTLYVCTPYSKVLALDVDSGKEKWRYDSKA--TAPnwqrcrglgyf 270
Cdd:COG1520 31 KVKQLWSASVGD-------GVGKGYSRLAPavaGDRVYAADADGRVAALDAATGKELWRVDLGEplSGG----------- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 271 edhstvttsqaetqPAACPRRLFLPTTDARLIAINADNGKVcddfgdHGTVDLSvgmGEIkpgyyqqTSTPLvagnvvvv 350
Cdd:COG1520 93 --------------VGADGGLVVVGTEDGEVIALDADDGEE------LWRARLS---SEV-------LAAPA-------- 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 351 ggrVADNY---STGEppGVVRAYDVHTGKLAWAWDPGNPNLTgLppegqtytRGTpnvwSAMSYDAKLNLIYLPTGnatp 427
Cdd:COG1520 135 ---VAGGRvvvRTGD--GRVYALDAATGERLWSYQRPVPALT-L--------RGT----SSPVIVGGAVLVGFANG---- 192
|
250 260 270
....*....|....*....|....*....|
gi 895847355 428 dfwagertalddkyssSIVAVDAATGQVRW 457
Cdd:COG1520 193 ----------------KLVALDLANGQPLW 206
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
199-457 |
9.21e-06 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 47.78 E-value: 9.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 199 VAWVAHTGDIPQSNGSGAEDQNTPLQIGDTLYVCTPYSKVLALDVDSGKEKWRYDskATAPNWQrcrglgyfedHSTVTT 278
Cdd:pfam13360 46 VALDAATGKLLWRQTLSGEVLGAPLVAGGRVFVVAGDGSLIALDAADGRRLWSYQ--RSGEPLA----------LRSSGS 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 279 sqaetqPAACPRRLFLPTTDARLIAINADNGKVCDDF---GDHGTVDLSVgMGEIkpgyyqqTSTPLVAGNVVvvggrva 355
Cdd:pfam13360 114 ------PAVVGDTVVAGFSSGKLVALDPATGKVRWEAplaAPRGTNELER-LVDI-------TGTPVVAGGRV------- 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 356 dNYSTGEppGVVRAYDVHTGKLAWAWDPGNPNltGLPPEGQTytrgtpnvwsamsydaklnlIYLPTGNATpdfwagert 435
Cdd:pfam13360 173 -FASAYQ--GRLVAFDAATGRRLWTREISGPN--GPILDGDL--------------------LYVVSDDGE--------- 218
|
250 260
....*....|....*....|..
gi 895847355 436 alddkysssIVAVDAATGQVRW 457
Cdd:pfam13360 219 ---------LYALDRATGAVVW 231
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
665-767 |
1.71e-05 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 47.71 E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 665 PFGTMSAVDLKTGKLVWQvpvgtvEDTGPLGIRmhmpipIGMPTLGaslstqSGLLFfAGTQDFYLRAFDTATGKEIWKD 744
Cdd:cd10276 46 ANGQVSAFNATTGKIIWE------TSLSGKGFL------GGTPAVG------NGKIF-VGTESGYLYALDAKDGSELWRT 106
|
90 100
....*....|....*....|...
gi 895847355 745 RLPVGSQSGPMTYVSpktGKQYI 767
Cdd:cd10276 107 EVSDSQLLSPPTYAD---GKIYV 126
|
|
| HdeD |
COG3247 |
Acid resistance membrane protein HdeD, DUF308 family [General function prediction only]; |
16-145 |
5.65e-05 |
|
Acid resistance membrane protein HdeD, DUF308 family [General function prediction only];
Pssm-ID: 442478 [Multi-domain] Cd Length: 178 Bit Score: 44.39 E-value: 5.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 16 WLLAGLMMLIGLAVGGLGFKLATVGGSSYFLIMGVAMVIAAILIFLNRISGIV----LYGIAFIAS----LFWAVS---- 83
Cdd:COG3247 39 ILFGILLLVSGIVQLVAAFRARGWGGRGWLLLLGILYIVAGILLLFNPLAGALvltlLIGIWLLVSgilrIVAAFRlrke 118
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 895847355 84 DAGWdFWPLFSRLFTFtVLAFLcAIVWPFlraanhtapnkAPAFGVAALLAVAMLVSlGWMF 145
Cdd:COG3247 119 VPGW-GWLLLSGILSL-LLGIL-LLFWPF-----------SGLWVLGLLLGIYLIFS-GIAL 165
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
365-528 |
7.13e-05 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 45.09 E-value: 7.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 365 GVVRAYDVHTGKLAWAWDPGNPNLTGLP-PEGQTYTRGTPNVwsAMSYDAKLNLIY----LPTGNATPDFWAGERT---A 436
Cdd:pfam13360 3 GVVTALDAATGAELWRVDLETGLGGGVAvDGGRLFVATGGGQ--LVALDAATGKLLwrqtLSGEVLGAPLVAGGRVfvvA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 437 LDDkyssSIVAVDAATGQVRWHFQTTHHDLWdFDLPSQPLLYdlpdgkGGTtpVLVQTSKqGMIFMLNRETGKPVAkveE 516
Cdd:pfam13360 81 GDG----SLIALDAADGRRLWSYQRSGEPLA-LRSSGSPAVV------GDT--VVAGFSS-GKLVALDPATGKVRW---E 143
|
170
....*....|....
gi 895847355 517 RPVPA--GNVEGER 528
Cdd:pfam13360 144 APLAAprGTNELER 157
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
445-469 |
5.40e-04 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 37.94 E-value: 5.40e-04
|
| Yip1 |
pfam04893 |
Yip1 domain; The Yip1 integral membrane domain contains four transmembrane alpha helices. The ... |
16-144 |
1.13e-03 |
|
Yip1 domain; The Yip1 integral membrane domain contains four transmembrane alpha helices. The domain is characterized by the motifs DLYGP and GY. The Yip1 protein is a golgi protein involved in vesicular transport that interacts with GTPases.
Pssm-ID: 461468 [Multi-domain] Cd Length: 173 Bit Score: 40.50 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 16 WLLAGLMMLIGLAVGGLGFKLATVGGSSYFLIMGVAMVIAAILIFLNRISG----------IVLYG--IAFIASLFWAVS 83
Cdd:pfam04893 38 LALLIGGTQVGWALSLTQLSALAVAIGALIGILLGLLILAALLYWLGRLFGgrgsfkqtlaVAGYAllPLILGGLLSGLL 117
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 895847355 84 DAGWdfwpLFSRLFTFTVLAFLCAIVWPFLRAAnHTAPNKAPAFGVAALLAVAMLVSLGWM 144
Cdd:pfam04893 118 PLLW----LPLSLVGLLFGIWSLYLLYLGLKEA-HGLSSKKAAALIAALLLLLLLLLLVLL 173
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
226-515 |
2.52e-03 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 41.07 E-value: 2.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 226 GDTLYVCTPYSKVLALDVDSGKEKWRydskatapnwqrcrglgyfedhsTVTTSQAETQPAACPRRLFLPTTDARLIAIN 305
Cdd:TIGR03300 105 GGLVFVGTEKGEVIALDAEDGKELWR-----------------------AKLSSEVLSPPLVANGLVVVRTNDGRLTALD 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 306 ADNGKVCDDFgDHGTVDLSVgmgeikpgyyQQTSTPLvagnvvvvggRVADNYSTGEPPGVVRAYDVHTGKLAWAWDPGN 385
Cdd:TIGR03300 162 AATGERLWTY-SRVTPPLTL----------RGSASPV----------IADGGVLVGFAGGKLVALDLQTGQPLWEQRVAL 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 386 P----------NLTGLP--PEGQTYtrgtpnvwsAMSYDAKLNLIYLPTGNAtpdFWAGE-----RTALDDKY------S 442
Cdd:TIGR03300 221 PkgrtelerlvDVDGDPvvDGGQVY---------AVSYQGRVAALDLRSGRV---LWKRDassyqGPAVDDNRlyvtdaD 288
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 895847355 443 SSIVAVDAATGQVRWhfqtTHHDLWDFDLpSQPLLYdlpdgkGGttpVLVQTSKQGMIFMLNRETGKPVAKVE 515
Cdd:TIGR03300 289 GVVVALDRRSGSELW----KNDELKYRQL-TAPAVL------GG---YLVVGDFEGYLHWLDRDDGSFVARLK 347
|
|
| PotE |
COG0531 |
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism]; |
13-143 |
3.08e-03 |
|
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain] Cd Length: 438 Bit Score: 40.65 E-value: 3.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 13 ILQWLLAGLMML-IGLAVG------------------GLGFKLATVGGSSYFL--IMGVAMVIAAILIFLNRI---SGIV 68
Cdd:COG0531 47 ILAWLIAGLLALlVALSYAelasafpraggaytyarrALGPLLGFLAGWALLLsyVLAVAAVAVAFGGYLSSLfpaGGSV 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 69 LYGIAFIASLFWA----VSDAGWdfwplFSRLFT---FTVLAFLCAIVWPFLRAANHT--APNKAPAFGVAALLAVAMLV 139
Cdd:COG0531 127 LIALVLILLLTLLnlrgVKESAK-----VNNILTvlkLLVLLLFIVVGLFAFDPANFTpfLPAGGGLSGVLAALALAFFA 201
|
....
gi 895847355 140 SLGW 143
Cdd:COG0531 202 FTGF 205
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
722-754 |
3.37e-03 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 35.63 E-value: 3.37e-03
10 20 30
....*....|....*....|....*....|...
gi 895847355 722 FAGTQDFYLRAFDTATGKEIWKDRLPVGSQSGP 754
Cdd:pfam01011 4 YLGSDDGYLYALDAETGKVLWSFKTGGAVLSSP 36
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
665-747 |
3.72e-03 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 40.30 E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 665 PFGTMSAVDLKTGKLVWQVPVGTvedtgPLGirmhmpipiGMPTLGaslstqSGLLFfAGTQDFYLRAFDTATGKEIWKD 744
Cdd:TIGR03300 73 ADGTVAALDAETGKRLWRVDLDE-----RLS---------GGVGAD------GGLVF-VGTEKGEVIALDAEDGKELWRA 131
|
...
gi 895847355 745 RLP 747
Cdd:TIGR03300 132 KLS 134
|
|
| SQR_TypeC_SdhC |
cd03499 |
Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) ... |
54-113 |
3.86e-03 |
|
Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Members of this family reduce high potential quinones such as ubiquinone. SQR is also called succinate dehydrogenase or Complex II, and is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Proteins in this subfamily are classified as Type C SQRs because they contain two transmembrane subunits and one heme group. The heme and quinone binding sites reside in the transmembrane subunits. The SdhC or CybL protein is one of the two transmembrane subunits of bacterial and eukaryotic SQRs. The two-electron oxidation of succinate in the flavoprotein active site is coupled to the two-electron reduction of quinone in the membrane anchor subunits via electron transport through FAD and three iron-sulfur centers. The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes.
Pssm-ID: 239579 Cd Length: 117 Bit Score: 37.90 E-value: 3.86e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 895847355 54 IAAILIFLNRISGIVLYGIAFIASLFWAVSDAG-WDFWPLFSRLFTFTVLAFLCAIVWPFL 113
Cdd:cd03499 14 LTAILSILHRITGVALFLGLPLLLWWLLASLSSpESFESVSALLGSWLGKLVLFGLTWALF 74
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
227-253 |
4.43e-03 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 35.25 E-value: 4.43e-03
10 20
....*....|....*....|....*..
gi 895847355 227 DTLYVCTPYSKVLALDVDSGKEKWRYD 253
Cdd:pfam01011 1 GTVYLGSDDGYLYALDAETGKVLWSFK 27
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
12-136 |
4.81e-03 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 40.37 E-value: 4.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 12 RILQWLLAGLMMLIGLAVGGLGFKLATVGGSSYFLIMGVAMVIAAILIF--------LNRISGIVLYGIAFIASLFWAVS 83
Cdd:COG5373 273 RWLNLLGFAGTFGWGLLWGVLLYRPELFLSTELFLIAFFLLFLAIALLFalrhpgplRGPVDGTLLFGTPLVAFALQLAL 352
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 895847355 84 DAGWDFWPLFSRLftftVLAFLCAIVWPFLRAanhtapnKAPAFGVAALLAVA 136
Cdd:COG5373 353 VADSGYGLALSAL----ALALLYLALALLLRR-------RRPALLALAFLALG 394
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
667-763 |
5.02e-03 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 39.31 E-value: 5.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 667 GTMSAVDLKTGKLVWQVpvgtVEDTGPLGIRmhmpipigmptlGASLSTQSGLLFFAGTQDFYLRAFDTATGKEIWKDRL 746
Cdd:pfam13360 83 GSLIALDAADGRRLWSY----QRSGEPLALR------------SSGSPAVVGDTVVAGFSSGKLVALDPATGKVRWEAPL 146
|
90
....*....|....*..
gi 895847355 747 PVGSQSGPMTYVSPKTG 763
Cdd:pfam13360 147 AAPRGTNELERLVDITG 163
|
|
| CynX |
COG2807 |
Cyanate permease [Inorganic ion transport and metabolism]; |
1-143 |
5.89e-03 |
|
Cyanate permease [Inorganic ion transport and metabolism];
Pssm-ID: 442057 [Multi-domain] Cd Length: 399 Bit Score: 39.86 E-value: 5.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 1 MAFGSAPrgIPRILQWLLAGLMMLIGLAVGGLGFKLATVGGSSYFL-----IMGVAMVIAAILI-------FLNRIS--- 65
Cdd:COG2807 66 FGLFAPL--APRLARRFGLERTLLLALLLLAAGLLLRSLAPSVALLlagtaLIGAGIAVGNVLLpglikrwFPDRVGlmt 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 66 ---GIVLYGIAFIASLF--WAVSDAGWDFWplfsrLFTFTVLAFLCAIVW-PFLRAANHTAPNKAPAFGVAALL--AVAM 137
Cdd:COG2807 144 glyTAAMGLGAALAAGLtvPLAAALGWRGA-----LAVWALLALLALLLWlPLLRRRPAAAAAAPAAASLRSLWrsPLAW 218
|
....*.
gi 895847355 138 LVSLGW 143
Cdd:COG2807 219 LLTLFF 224
|
|
| PQQ |
smart00564 |
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline ... |
717-743 |
6.83e-03 |
|
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.
Pssm-ID: 128836 [Multi-domain] Cd Length: 33 Bit Score: 34.82 E-value: 6.83e-03
10 20
....*....|....*....|....*..
gi 895847355 717 SGLLFFAGTQDFYLRAFDTATGKEIWK 743
Cdd:smart00564 5 SDGTVYVGSTDGTLYALDAKTGEILWT 31
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
665-754 |
6.88e-03 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 38.92 E-value: 6.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 665 PFGTMSAVDLKTGKLVWQVPVGTVEDTGPLGirmhmpipigmptlgaslstqSGLLFFAGTQDFYLRAFDTATGKEIWKD 744
Cdd:pfam13360 1 ADGVVTALDAATGAELWRVDLETGLGGGVAV---------------------DGGRLFVATGGGQLVALDAATGKLLWRQ 59
|
90
....*....|
gi 895847355 745 RLPVGSQSGP 754
Cdd:pfam13360 60 TLSGEVLGAP 69
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
193-252 |
9.34e-03 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 38.54 E-value: 9.34e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 895847355 193 NVSSLKVAWVAHTGDIPQSNGSGAedQNTPLQIGDTLYVCTPYSKVLALDVDSGKEKWRY 252
Cdd:pfam13360 176 AYQGRLVAFDAATGRRLWTREISG--PNGPILDGDLLYVVSDDGELYALDRATGAVVWKT 233
|
|
| |
