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Conserved domains on  [gi|896026364|ref|WP_049086671|]
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MULTISPECIES: glycerone kinase [Klebsiella]

Protein Classification

dihydroxyacetone kinase family protein( domain architecture ID 1001500)

dihydroxyacetone kinase family protein similar to human triokinase/FMN cyclase and dihydroxyacetone kinase subunit L (DhaL), which is the ADP-binding subunit of dihydroxyacetone kinase that catalyzes the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP

Gene Ontology:  GO:0004371|GO:0006071|GO:0005524
PubMed:  16505971|15476397

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK14479 super family cl29418
dihydroxyacetone kinase; Provisional
 3-547 0e+00

dihydroxyacetone kinase; Provisional


The actual alignment was detected with superfamily member TIGR02361:

Pssm-ID: 475197 [Multi-domain]  Cd Length: 574  Bit Score: 600.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364    3 QFFFNQRANLVNDVIEGTIIASPWnnLARLESDpaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDL 82
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPG--LQLLESR---KVVYRRDLNKDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   83 FASPSVDAVLTAIQAVTG-DAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNK----HPRGIAGTIL 157
Cdd:TIGR02361  76 FASPSTKQILAAIRAVVGsEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKgglvGRRGLAGTVL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  158 VHKVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAE-I 236
Cdd:TIGR02361 156 VHKIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEPELKEDEMELGMGIHNEPGAKRISPIPSSDlV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  237 VTLMAEKLSA--------ALPETGRLAVMINNLGGVSIAEMAILT-RELAHTPLQ-QRIDWLIGPASLVTALDMKGFSLT 306
Cdd:TIGR02361 236 VQLMLKKLLDetdkrsyvKFNEGDEVVLLVNNLGGVSNLELGIIAdEVVEQLALHyNIIPVRIYSGTFMTSLNGPGFSIT 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  307 AIVLEE---SIEKALLSAVETAGW----QTPVQPREIS---VMPSSLRSTRVEFEPSENSVVADYVERVTGTLSDLEADL 376
Cdd:TIGR02361 316 LLNATEagkSILDLLDAPTEAPGWpvaaYSSKPWREKRevvSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHL 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  377 NALDAKVGDGDTGSTFAAGARDIADLLQRRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGAS---- 452
Cdd:TIGR02361 396 TKLDTKAGDGDCGSTLARGAEAILELLKSKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASkkee 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  453 -----VAEALNAGLAQMKFYGGADEGDRTMIDALQPALAALAAEPENLQAAFAAAQAGADRTLHaSKANAGRASYLNSDS 527
Cdd:TIGR02361 476 itpeaWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSNLNAAVKAAEAGAEATKK-MKAKAGRASYVSSEA 554

                         570       580
                  ....*....|....*....|
gi 896026364  528 LRGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02361 555 LEGVPDPGAVGLAAWLRGLA 574
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 3-547 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 600.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364    3 QFFFNQRANLVNDVIEGTIIASPWnnLARLESDpaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDL 82
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPG--LQLLESR---KVVYRRDLNKDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   83 FASPSVDAVLTAIQAVTG-DAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNK----HPRGIAGTIL 157
Cdd:TIGR02361  76 FASPSTKQILAAIRAVVGsEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKgglvGRRGLAGTVL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  158 VHKVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAE-I 236
Cdd:TIGR02361 156 VHKIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEPELKEDEMELGMGIHNEPGAKRISPIPSSDlV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  237 VTLMAEKLSA--------ALPETGRLAVMINNLGGVSIAEMAILT-RELAHTPLQ-QRIDWLIGPASLVTALDMKGFSLT 306
Cdd:TIGR02361 236 VQLMLKKLLDetdkrsyvKFNEGDEVVLLVNNLGGVSNLELGIIAdEVVEQLALHyNIIPVRIYSGTFMTSLNGPGFSIT 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  307 AIVLEE---SIEKALLSAVETAGW----QTPVQPREIS---VMPSSLRSTRVEFEPSENSVVADYVERVTGTLSDLEADL 376
Cdd:TIGR02361 316 LLNATEagkSILDLLDAPTEAPGWpvaaYSSKPWREKRevvSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHL 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  377 NALDAKVGDGDTGSTFAAGARDIADLLQRRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGAS---- 452
Cdd:TIGR02361 396 TKLDTKAGDGDCGSTLARGAEAILELLKSKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASkkee 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  453 -----VAEALNAGLAQMKFYGGADEGDRTMIDALQPALAALAAEPENLQAAFAAAQAGADRTLHaSKANAGRASYLNSDS 527
Cdd:TIGR02361 476 itpeaWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSNLNAAVKAAEAGAEATKK-MKAKAGRASYVSSEA 554

                         570       580
                  ....*....|....*....|
gi 896026364  528 LRGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02361 555 LEGVPDPGAVGLAAWLRGLA 574
PTZ00375 PTZ00375
dihydroxyacetone kinase-like protein; Provisional
 1-547 1.13e-129

dihydroxyacetone kinase-like protein; Provisional


Pssm-ID: 185583 [Multi-domain]  Cd Length: 584  Bit Score: 390.71  E-value: 1.13e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   1 MSQFFFNQRANLVNDVIEGTIIASPwNNLARLESdpaIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCG 80
Cdd:PTZ00375   2 VSKKFINSPEKVVSEAVDGLCMTNN-DSLKRIEN---TNVVVRSDIDKTKVLLISGGGSGHEPAHAGFVGKGWLTAAVCG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  81 DLFASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDIS--LPDNKHPRGIAGTILV 158
Cdd:PTZ00375  78 SVFASPSTKHVLAAIEYVPNGPGCLLIVKNYTGDILNFELAVEQARARGIQVETVLVADDAAfgTKDIANRRGIAGTVLL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 159 HKVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDaETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVT 238
Cdd:PTZ00375 158 YKILGAAAEKGASLTQLKKLADRISSNMRSIGVSLSSCSLPGN-DPSSTVPPGTMEVGLGIHGEKGLARIPFQGAKDLVK 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 239 LMAEKL-----------SAALPETGRLAVMINNLGGVSIAEMAILTRELAHTPLQQRIDWL-IGPASLVTALDMKGFSLT 306
Cdd:PTZ00375 237 FLIGILlgkgkkrgggkTTAIREGAKVALLVNNLGSTTDLEMSILAHHALRQLAQAGLTVVgVHSGRLMTSLEMHGFSLT 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 307 AIVLEESIEKALLSAVETA---------GWQTPVQPRE-ISVMPSSLRSTRVEFEPSENSVVADYVERVTGTLSDLEADL 376
Cdd:PTZ00375 317 LLPIEDEDDLQLLDTNQKPllnfhtpqsSWATAKGPLSaLQLAKPEAEAASRKAATPTNSLLRSVLERVFETLIESENYL 396

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 377 NALDAKVGDGDTGSTFAAGARDIADLLQrRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGA----- 451
Cdd:PTZ00375 397 NELDAEVGDGDLGSGLERSSKAVLESLP-YLPLEANVRKTLTLISKAVADAFGGSSGPLYGAFLLGGANALAEALnggna 475

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 452 --SVAEALNAGLAQMKFYGGADEGDRTMIDALQPAL---------AALAAEPENLQAAFAAAQAGADRTLHAsKANAGRA 520
Cdd:PTZ00375 476 vdAVRAALAAGSHSIQELGGARVGDRTMVDVLIPFAealnscpsvNEAASSPELLKACSEEAREAAEATALL-PAKHGRS 554

                        570       580
                 ....*....|....*....|....*..
gi 896026364 521 SYLNSDSLrGNMDPGAHAVAMVFKALA 547
Cdd:PTZ00375 555 RYLEGKEL-GKKDPGAELVVAWVEALA 580
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
 18-326 2.40e-116

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 346.74  E-value: 2.40e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   18 EGTIIASPwNNLARLESDpaiRVVVRRDL-DKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFASPSVDAVLTAIQ 96
Cdd:pfam02733   1 EGLAAAHP-DLLRLVPGP---RVVVRADApPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   97 AVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKVAGYFAERGHNLA 173
Cdd:pfam02733  77 AVDGGAGVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVGDSGGTvgrRGVAGTVLVHKIAGAAAEAGASLD 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  174 TVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLMAEKLSAALPETG- 252
Cdd:pfam02733 157 EVARLAEKVNANTRTMGVALSPCTVPGAGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDDPLLPg 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896026364  253 -RLAVMINNLGGVSIAEMAILTRELAHTpLQQR----IDWLIGPasLVTALDMKGFSLTAIVLEESIEKALLSAVETAG 326
Cdd:pfam02733 237 dEVAVLVNGLGGTPLLELYIVYRRVLEL-LEEKgikvVRSLVGE--YMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 5-201 1.12e-20

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 90.26  E-value: 1.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   5 FFNQRANLVNDVIEGTIIASPWNNLARL--ESDPAIRVVVRRDLDKnnVAVISGGGSGhepahaGFVGKGMLTAAVCGDL 82
Cdd:COG2376   14 FLNDLDAVVGDGDHGINMARGFDAVRAAldAAPADPGVVLRAAGMK--VASVVGGGSG------GLVGTGFLDAAVALKG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  83 FASPSVDAVLTAIQAVT---GDAGcllivKNYTGDRLNFGLAAEKARRMgynVEMLIVGDDislpdnkhprgiagtilvh 159
Cdd:COG2376   86 ETSPTADQVAAALRAADegiQGRG-----VAYTGDKTNFDAAAPAAEAI---EEAVAAGTA------------------- 138

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 896026364 160 kvagyFAErghNLATVLREAQYAAGHTFSLGLALASCHLPQD 201
Cdd:COG2376  139 -----AAA---ALDEAAAAAEKGAEATRSMGAALGRATYPGE 172
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 3-547 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 600.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364    3 QFFFNQRANLVNDVIEGTIIASPWnnLARLESDpaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDL 82
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPG--LQLLESR---KVVYRRDLNKDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   83 FASPSVDAVLTAIQAVTG-DAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNK----HPRGIAGTIL 157
Cdd:TIGR02361  76 FASPSTKQILAAIRAVVGsEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKgglvGRRGLAGTVL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  158 VHKVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAE-I 236
Cdd:TIGR02361 156 VHKIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEPELKEDEMELGMGIHNEPGAKRISPIPSSDlV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  237 VTLMAEKLSA--------ALPETGRLAVMINNLGGVSIAEMAILT-RELAHTPLQ-QRIDWLIGPASLVTALDMKGFSLT 306
Cdd:TIGR02361 236 VQLMLKKLLDetdkrsyvKFNEGDEVVLLVNNLGGVSNLELGIIAdEVVEQLALHyNIIPVRIYSGTFMTSLNGPGFSIT 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  307 AIVLEE---SIEKALLSAVETAGW----QTPVQPREIS---VMPSSLRSTRVEFEPSENSVVADYVERVTGTLSDLEADL 376
Cdd:TIGR02361 316 LLNATEagkSILDLLDAPTEAPGWpvaaYSSKPWREKRevvSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHL 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  377 NALDAKVGDGDTGSTFAAGARDIADLLQRRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGAS---- 452
Cdd:TIGR02361 396 TKLDTKAGDGDCGSTLARGAEAILELLKSKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASkkee 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  453 -----VAEALNAGLAQMKFYGGADEGDRTMIDALQPALAALAAEPENLQAAFAAAQAGADRTLHaSKANAGRASYLNSDS 527
Cdd:TIGR02361 476 itpeaWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSNLNAAVKAAEAGAEATKK-MKAKAGRASYVSSEA 554

                         570       580
                  ....*....|....*....|
gi 896026364  528 LRGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02361 555 LEGVPDPGAVGLAAWLRGLA 574
PTZ00375 PTZ00375
dihydroxyacetone kinase-like protein; Provisional
 1-547 1.13e-129

dihydroxyacetone kinase-like protein; Provisional


Pssm-ID: 185583 [Multi-domain]  Cd Length: 584  Bit Score: 390.71  E-value: 1.13e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   1 MSQFFFNQRANLVNDVIEGTIIASPwNNLARLESdpaIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCG 80
Cdd:PTZ00375   2 VSKKFINSPEKVVSEAVDGLCMTNN-DSLKRIEN---TNVVVRSDIDKTKVLLISGGGSGHEPAHAGFVGKGWLTAAVCG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  81 DLFASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDIS--LPDNKHPRGIAGTILV 158
Cdd:PTZ00375  78 SVFASPSTKHVLAAIEYVPNGPGCLLIVKNYTGDILNFELAVEQARARGIQVETVLVADDAAfgTKDIANRRGIAGTVLL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 159 HKVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDaETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVT 238
Cdd:PTZ00375 158 YKILGAAAEKGASLTQLKKLADRISSNMRSIGVSLSSCSLPGN-DPSSTVPPGTMEVGLGIHGEKGLARIPFQGAKDLVK 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 239 LMAEKL-----------SAALPETGRLAVMINNLGGVSIAEMAILTRELAHTPLQQRIDWL-IGPASLVTALDMKGFSLT 306
Cdd:PTZ00375 237 FLIGILlgkgkkrgggkTTAIREGAKVALLVNNLGSTTDLEMSILAHHALRQLAQAGLTVVgVHSGRLMTSLEMHGFSLT 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 307 AIVLEESIEKALLSAVETA---------GWQTPVQPRE-ISVMPSSLRSTRVEFEPSENSVVADYVERVTGTLSDLEADL 376
Cdd:PTZ00375 317 LLPIEDEDDLQLLDTNQKPllnfhtpqsSWATAKGPLSaLQLAKPEAEAASRKAATPTNSLLRSVLERVFETLIESENYL 396

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 377 NALDAKVGDGDTGSTFAAGARDIADLLQrRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGA----- 451
Cdd:PTZ00375 397 NELDAEVGDGDLGSGLERSSKAVLESLP-YLPLEANVRKTLTLISKAVADAFGGSSGPLYGAFLLGGANALAEALnggna 475

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 452 --SVAEALNAGLAQMKFYGGADEGDRTMIDALQPAL---------AALAAEPENLQAAFAAAQAGADRTLHAsKANAGRA 520
Cdd:PTZ00375 476 vdAVRAALAAGSHSIQELGGARVGDRTMVDVLIPFAealnscpsvNEAASSPELLKACSEEAREAAEATALL-PAKHGRS 554

                        570       580
                 ....*....|....*....|....*..
gi 896026364 521 SYLNSDSLrGNMDPGAHAVAMVFKALA 547
Cdd:PTZ00375 555 RYLEGKEL-GKKDPGAELVVAWVEALA 580
PRK14479 PRK14479
dihydroxyacetone kinase; Provisional
 5-548 2.73e-123

dihydroxyacetone kinase; Provisional


Pssm-ID: 237723 [Multi-domain]  Cd Length: 568  Bit Score: 373.76  E-value: 2.73e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   5 FFNQRANLVNDVIEGTIIASPwnnlaRLESDPAIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFA 84
Cdd:PRK14479   4 LINDPSTFVEEMLEGFVAAHP-----DLVRLVPGGVVRRTPTPEGKVAVVSGGGSGHEPAFAGYVGPGMLDAAVCGNVFT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  85 SPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISL-PDNKHP--RGIAGTILVHKV 161
Cdd:PRK14479  79 SPSADQVYAAIRAADGGAGVLLIVGNYAGDVMNFGLAAELARAEGIDVRTVVVTDDVASaPSGETAgrRGIAGTVLVFKI 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 162 AGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPqdAETAPRHH--ADQAELGMGIHGEPGASVIATQNSAEIVTL 239
Cdd:PRK14479 159 AGAAAEAGLDLDEVAAIARKANARTRSMGVALDGCTLP--GAGEPLFTlpEGEMELGLGIHGEPGIEREALPTADELADR 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 240 MAEKLSAALPE--TGRLAVMINNLGGVSIAEMAILTRELAHTpLQQR----IDWLIGpaSLVTALDMKGFSLTAIVLEES 313
Cdd:PRK14479 237 LVDRILADLPLgaGERVAVLVNGLGATPYEELFVVYGAVARL-LAARgitvVRPEVG--EFVTSLDMAGASLTLMKLDDE 313

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 314 IEKALLSAVETAGWQT--PVQPREISVMPSSlRSTRVEFEPSENS-----VVADYVERVTGTLSDLEADLNALDAKVGDG 386
Cdd:PRK14479 314 LEELWDAPADTPAFRRggAVEPVEYVEAAEE-DDAEEPPRASKASrataaNLVAALDAVAEALIDNEDELGELDAVAGDG 392

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 387 DTGSTFAAGARDIADLLQRRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQ-----GASVAEALNAGL 461
Cdd:PRK14479 393 DHGIGMARGSKAALAAARAAVEAGAGAGSVLAAAGDAWADHAGGTSGPLWGTALRAAGKALGDkdeptAADFAAAVRAAV 472

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 462 AQMKFYGGADEGDRTMIDALQPALAALAAEPENLQAAFAAAQAGADRTLHASKANA------GRASYLNSDSLrGNMDPG 535
Cdd:PRK14479 473 DAIQELGGAQVGDKTMVDALVPFADALEAAAAAGADLAEAWAAAAEAAEEGAEATAdlvprmGRARYLGERSL-GTPDAG 551

                        570
                 ....*....|...
gi 896026364 536 AHAVAMVFKALAQ 548
Cdd:PRK14479 552 AVSLALIFTAIAG 564
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
 18-326 2.40e-116

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 346.74  E-value: 2.40e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   18 EGTIIASPwNNLARLESDpaiRVVVRRDL-DKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFASPSVDAVLTAIQ 96
Cdd:pfam02733   1 EGLAAAHP-DLLRLVPGP---RVVVRADApPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   97 AVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKVAGYFAERGHNLA 173
Cdd:pfam02733  77 AVDGGAGVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVGDSGGTvgrRGVAGTVLVHKIAGAAAEAGASLD 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  174 TVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLMAEKLSAALPETG- 252
Cdd:pfam02733 157 EVARLAEKVNANTRTMGVALSPCTVPGAGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDDPLLPg 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896026364  253 -RLAVMINNLGGVSIAEMAILTRELAHTpLQQR----IDWLIGPasLVTALDMKGFSLTAIVLEESIEKALLSAVETAG 326
Cdd:pfam02733 237 dEVAVLVNGLGGTPLLELYIVYRRVLEL-LEEKgikvVRSLVGE--YMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
PRK14481 PRK14481
dihydroxyacetone kinase subunit DhaK; Provisional
 5-327 7.55e-98

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 237724  Cd Length: 331  Bit Score: 299.81  E-value: 7.55e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   5 FFNQRANLVNDVIEGTIIASPwnNLARLESDPaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFA 84
Cdd:PRK14481   4 LINDPETVVDEMLEGLVAAHP--DLVTRIDDT--DVIVRKDKPPGKVALVSGGGSGHEPAHAGFVGEGMLDAAVCGAVFT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  85 SPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKV 161
Cdd:PRK14481  80 SPTPDQILEAIKAVDTGAGVLLIVKNYSGDVMNFEMAAELAEMEGIEVASVVVDDDVAVEDSLYTqgrRGVAGTVFVHKI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 162 AGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLMA 241
Cdd:PRK14481 160 AGAAAEAGASLDEVKALAEKVNPNIRSMGVALSPCTVPAVGKPGFDLGDDEIEIGIGIHGEPGRRREKLKPADEIAEELL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 242 EKLSAALPET--GRLAVMINNLGGVSIAEMAILTRELAHTpLQQR----IDWLIGpaSLVTALDMKGFSLTAIVLEESIE 315
Cdd:PRK14481 240 EKILEDLKLVagDEVLVLVNGMGATPLMELYIVYNDVAEL-LEERgvtvARSLVG--NYMTSLDMAGFSITLLKLDDELL 316

                        330
                 ....*....|..
gi 896026364 316 KALLSAVETAGW 327
Cdd:PRK14481 317 ELLDAPVDTPAL 328
dhaK1 TIGR02363
dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) ...
 5-327 6.49e-86

dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the DhaK subunit of the latter type of dihydroxyacetone kinase, but it specifically excludes the DhaK paralog DhaK2 (TIGR02362) found in the same operon as DhaK and DhaK in the Firmicutes.


Pssm-ID: 274098  Cd Length: 329  Bit Score: 269.23  E-value: 6.49e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364    5 FFNQRANLVNDVIEGTIIASPwnNLARLESDPaiRVVVRRDLDKNN-VAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLF 83
Cdd:TIGR02363   4 LINDPEDVVAEMLDGLVKAHP--ELVTLVADT--RVIVRKDKKVNGkVALVSGGGSGHEPAHAGFVGYGMLDAAVPGEVF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   84 ASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHK 160
Cdd:TIGR02363  80 TSPTPDQILEAIKAVDQGAGVLLIVKNYTGDVMNFEMAAELAEDEGIKVATVVVDDDIAVEDSLYTagrRGVAGTVFVHK 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  161 VAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLM 240
Cdd:TIGR02363 160 IAGAAAEKGASLDELKSLGEKVNPNTKSIGVALTACTVPAVGKPGFDLADDEMEIGVGIHGEPGIRREKMKSSDEIADEL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  241 AEKL--SAALPETGRLAVMINNLGGVSIAEMAILTRELAHTPLQQRID---WLIGpaSLVTALDMKGFSLTAIVLEESIE 315
Cdd:TIGR02363 240 LDKLldDLGLQSGDRVIVLVNGMGATPLMELYIFYNDVQRLLEQRGVNvarTLVG--NYMTSLDMAGFSLTLLKLDDELL 317

                         330
                  ....*....|..
gi 896026364  316 KALLSAVETAGW 327
Cdd:TIGR02363 318 ELWDAPVTTIAL 329
PRK14483 PRK14483
DhaKLM operon coactivator DhaQ; Provisional
 4-327 7.20e-68

DhaKLM operon coactivator DhaQ; Provisional


Pssm-ID: 172956  Cd Length: 329  Bit Score: 222.23  E-value: 7.20e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   4 FFFNQRANLVNDVIEGTIIASPwnNLARLesdPAIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLF 83
Cdd:PRK14483   3 KIMNDVQNIVQDMLHGFYFAHP--NLDET---NNIPYVYDIEKDDQLVPIISGGGSGHEPAHIGYVGKGMLTAAVNGSIF 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  84 ASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPD----NKHPRGIAGTILVH 159
Cdd:PRK14483  78 TPPTAEQILAATRLVPKGKGVFFIIKNFEADVAEFSAAIQIARQEGRQIKYIIVHDDISVEDdasfNKRRRGVAGTVLLH 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 160 KVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTL 239
Cdd:PRK14483 158 KILGAAALEGASLDELEQLGLSLTENIATLGVALSPANLPVAGLPSFDLNEDEISYGIGIHGEPGYRKEPFSSSEILAIE 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 240 MAEKLSAAL--PETGRLAVMINNLGGVSIAEMAILT----RELAHTPLQqrIDWlIGPASLVTALDMKGFSLTAIVLEES 313
Cdd:PRK14483 238 LVNKLKSKYrwQKGDNFILLINGLGATTLMEQYIFAndirRLLELEGLQ--ITF-VKVGTLLTSLDMKGISLTLLKVKDP 314

                        330
                 ....*....|....*
gi 896026364 314 -IEKALLSAVETAGW 327
Cdd:PRK14483 315 dWLDWLKAPTRAAAW 329
PRK11468 PRK11468
dihydroxyacetone kinase subunit DhaK; Provisional
 7-327 8.97e-65

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 183150  Cd Length: 356  Bit Score: 214.88  E-value: 8.97e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   7 NQRANLVNDVIEGTIIASPwnNLaRLESDPaiRVVVRRDLD-KNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFAS 85
Cdd:PRK11468   6 NDVEDVLDEQLAGLAKAHP--EL-TLHQDP--VYVTRADAPvAGKVALLSGGGSGHEPMHCGFVGQGMLDGACPGEIFTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  86 PSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKVA 162
Cdd:PRK11468  81 PTPDQMFECAMQVDGGEGVLLIIKNYTGDVLNFETATELLHDSGVKVTTVLIDDDVAVKDSLYTagrRGVANTVLIEKLV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 163 GYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLMAE 242
Cdd:PRK11468 161 GAAAERGYSLDQCAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIHGEPGIDRRPFSSLDQTVDEMFD 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 243 KL--------------------------SAALPETGRLAVMINNLGGVSIAEMAILTRELAHTPLQQRIDW---LIGPas 293
Cdd:PRK11468 241 TLlengsyhrtlrfwdrqqgswqeeeqtKQPLQSGDRVIALVNNLGATPLSELYGVYNRLATRCEQAGLTIernLIGA-- 318

                        330       340       350
                 ....*....|....*....|....*....|....
gi 896026364 294 LVTALDMKGFSLTAIVLEESIEKALLSAVETAGW 327
Cdd:PRK11468 319 YCTSLDMQGFSITLLKVDDETLALWDAPVHTPAL 352
dhaK1b TIGR02362
probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase ...
 7-327 1.42e-53

probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form with a phosphoprotein donor related to PTS transport proteins. This family represents a protein, unique to the Firmicutes (low GC Gram-positives), that appears to be a divergent second copy of the K subunit of that complex; its gene is always found in operons with the other three proteins of the complex.


Pssm-ID: 213706  Cd Length: 326  Bit Score: 184.62  E-value: 1.42e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364    7 NQRANLVNDVIEGTIIASPwnNLARLESDPAIRvvvRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFASP 86
Cdd:TIGR02362   4 NEPQNAVSQAIQGIQWAYP--NLVQVPDLPGIY---DSNFDDQQIPIISGGGSGHEPAHWGYVGEGMLSAAIMGDVFVPP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   87 SVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISL-PDN--KHPRGIAGTILVHKVAG 163
Cdd:TIGR02362  79 TAQDILEAIRQVDRGKGVFVIIKNFEADLSEFSQAIQQARQEGRQIKYIIVHDDISVeHESfkQRRRGVAGTILVHKILG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  164 YFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLMAEK 243
Cdd:TIGR02362 159 AAAAEGASLDELEHIAAALVTNIATIGVAAKSARIPGQSTPSFDLEEGEIYYGIGIHGEPGYRTEPFVSSEHLAVELVNK 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  244 LSAAL--PETGRLAVMINNLGGVSIAE--------MAILTRELAHTPlqqridwLIGPASLVTALDMKGFSLTAIVL-EE 312
Cdd:TIGR02362 239 LKLKFrwQADDHYAVLVNNLGGTTPMEqmvfnndvHELLALEALHLP-------FIKVGTFLTSLDMHGLSLTLLRLkDP 311

                         330
                  ....*....|....*
gi 896026364  313 SIEKALLSAVETAGW 327
Cdd:TIGR02362 312 QWLDYLNAPVDAAAW 326
Dak2 pfam02734
DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase ...
 382-548 1.09e-23

DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.


Pssm-ID: 460668 [Multi-domain]  Cd Length: 175  Bit Score: 98.02  E-value: 1.09e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  382 KVGDGDTGSTFAAGARDIADLLQrrQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQ-----GASVAEA 456
Cdd:pfam02734   1 PVGDGDHGTNMARGFEAALKALE--DLEPASLAEVLKALAMALLSGAGGNSGPLYGQFFRGAAKALKGkeeldAEDLAAA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  457 LNAGLAQMKFYGGADEGDRTMID-------ALQPALAALAAEPENLQAAFAAAQAGADRTLHaSKANAGRASYLNSDSLr 529
Cdd:pfam02734  79 LEAALEAIQARGKARPGDKTMLDvlrpaaeALEAAAEAGEDLAEALEAAVKAAEEGAEATKE-LLAKLGRASYLGERSI- 156

                         170
                  ....*....|....*....
gi 896026364  530 GNMDPGAHAVAMVFKALAQ 548
Cdd:pfam02734 157 GVVDPGATGLALILEALLE 175
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 5-201 1.12e-20

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 90.26  E-value: 1.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364   5 FFNQRANLVNDVIEGTIIASPWNNLARL--ESDPAIRVVVRRDLDKnnVAVISGGGSGhepahaGFVGKGMLTAAVCGDL 82
Cdd:COG2376   14 FLNDLDAVVGDGDHGINMARGFDAVRAAldAAPADPGVVLRAAGMK--VASVVGGGSG------GLVGTGFLDAAVALKG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  83 FASPSVDAVLTAIQAVT---GDAGcllivKNYTGDRLNFGLAAEKARRMgynVEMLIVGDDislpdnkhprgiagtilvh 159
Cdd:COG2376   86 ETSPTADQVAAALRAADegiQGRG-----VAYTGDKTNFDAAAPAAEAI---EEAVAAGTA------------------- 138

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 896026364 160 kvagyFAErghNLATVLREAQYAAGHTFSLGLALASCHLPQD 201
Cdd:COG2376  139 -----AAA---ALDEAAAAAEKGAEATRSMGAALGRATYPGE 172
dha_L_ycgS TIGR02365
dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone ...
 373-547 3.58e-14

dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.


Pssm-ID: 274099 [Multi-domain]  Cd Length: 194  Bit Score: 71.23  E-value: 3.58e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  373 EADLNALDAKVGDGDTGSTFAAGARDIADLLQrrqlplanlATLLALIGERLTVV-------MGGSSGVLMSIFFTAAGQ 445
Cdd:TIGR02365  16 KEYLTELDRAIGDGDHGINMARGFSEVKEKLD---------AFKDKTIGEILKNTgmtliskVGGASGPLYGTAFLKASK 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364  446 KLEQ-----GASVAEALNAGLAQMKFYGGADEGDRTMIDA---LQPALAALAAEPENLQAAFAAAQAGADRT--LHASKa 515
Cdd:TIGR02365  87 ALKDdeildAEDLAEILQAGLEGIQSRGKATPGEKTMVDVwapVVEALRKAADEPDALAAAREAAEQGAEATkdMQATK- 165

                         170       180       190
                  ....*....|....*....|....*....|..
gi 896026364  516 naGRASYLNSDSLrGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02365 166 --GRASYLGERSI-GHIDPGATSSYYLFQALA 194
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 362-548 8.93e-12

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 64.45  E-value: 8.93e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 362 VERVTGTLSDLEADLNALDAKVGDGDTGSTFAAGARDIADLLQrrqLPLANLATLLALIGERLTVVMGGSSGVLMSIFFT 441
Cdd:COG2376    1 MKAVADVIAENRKFLNDLDAVVGDGDHGINMARGFDAVRAALD---AAPADPGVVLRAAGMKVASVVGGGSGGLVGTGFL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 442 AAGQKLEQGAS-----VAEALNAGLAQMKFYGGADEGDRTMID-------ALQPALAALAAEPENLQAAFAAAQAGAD-- 507
Cdd:COG2376   78 DAAVALKGETSptadqVAAALRAADEGIQGRGVAYTGDKTNFDaaapaaeAIEEAVAAGTAAAAALDEAAAAAEKGAEat 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 896026364 508 RTLHASKanaGRASYLNSDSlRGNMDPGAHAVAMVFKALAQ 548
Cdd:COG2376  158 RSMGAAL---GRATYPGERS-PGHPDPGATSVALLLNGLGA 194
PRK10005 PRK10005
dihydroxyacetone kinase ADP-binding subunit DhaL;
376-548 1.21e-06

dihydroxyacetone kinase ADP-binding subunit DhaL;


Pssm-ID: 182192 [Multi-domain]  Cd Length: 210  Bit Score: 49.35  E-value: 1.21e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 376 LNALDAKVGDGDTGSTFAAGARDIADLLqrrqlplanLATLLALIGERL-TVVM------GGSSGVLMSIFFTAAGQKLE 448
Cdd:PRK10005  26 LTGLDREIGDADHGLNMNRGFSKVVEKL---------PAIADKDIGFILkNTGMtllssvGGASGPLYGTFFIRAAQATQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896026364 449 QGASVA-----EALNAGLAQMKFYGGADEGDRTMIDALQPALAALAAEPEN---LQAAFAAAQAGADRTLHAS---KANA 517
Cdd:PRK10005  97 ARQSLTleelyQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQnlsVPAALNAAVSIAESAAQSTitmQARK 176

                        170       180       190
                 ....*....|....*....|....*....|.
gi 896026364 518 GRASYLNSDSLrGNMDPGAHAVAMVFKALAQ 548
Cdd:PRK10005 177 GRASYLGERSI-GHQDPGATSVMFMMQALAL 206
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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