|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05636 |
PRK05636 |
replicative DNA helicase; Provisional |
66-523 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180177 [Multi-domain] Cd Length: 505 Bit Score: 730.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 66 RDWERDRGRGARASAVAGATFeRTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEI 145
Cdd:PRK05636 47 TRGGDRRGFKRREESREYRDF-RQPPYDNEAEQGVLGAMLLSPDTVIDIVEVLTPEDFYRPAHQLIFQAIIDLFSDNKEI 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 146 DPILLAGRLDRTGDLERIGGPLYLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDTEPEQLVDEA 225
Cdd:PRK05636 126 DPVIVAGRLDRTNDLERVGGAPYLHTLIQSVPTAANARYYAEIVSEKAVLRRLVDAGTRVVQLGYEGDEGAEIDSVIDRA 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 226 QQLIFSVGRENTKNDYVPIADVLDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDF 305
Cdd:PRK05636 206 QQEVFAVSQKNQSEDYAVLADILDPTMDELEMLSSQGGIATGIPTGFKDLDDLTNGLRGGQMIIVAARPGVGKSTLALDF 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 306 MRSASIRNGMTSAIFSLEMSRNEIMMRIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRA 385
Cdd:PRK05636 286 MRSASIKHNKASVIFSLEMSKSEIVMRLLSAEAEVRLSDMRGGKMDEDAWEKLVQRLGKIAQAPIFIDDSANLTMMEIRS 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 386 KARQLKQKHDLKMIVVDYLQLMSSGKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESG 465
Cdd:PRK05636 366 KARRLKQKHDLKLIVVDYLQLMSSGKRVESRQQEVSEFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESG 445
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 896153470 466 SLEQDADIVMLIYRPDSQEADHERAGEADIIVAKHRGGPTGSIAVAHQLHYSRFANLA 523
Cdd:PRK05636 446 SLEQDADMVMLLYRPDSQDKDDERAGEADIILAKHRGGPIDTVQVAHQLHYSRFVDMA 503
|
|
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
90-523 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 674.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 90 PPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLYL 169
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 170 HTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDtePEQLVDEAQQLIFSVGRENTKNDYVPIADVLD 249
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTGD--VEELLDEAEQKIFEIAESRTSKGFKSIKEILK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 250 DTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSLEMSRNEI 329
Cdd:TIGR00665 159 EAVEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGKPVAFFSLEMSAEQL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 330 MMRIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQLKQKHDLKMIVVDYLQLMSS 409
Cdd:TIGR00665 239 VMRMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEAPLYIDDTPGLTITELRAKARRLKREHGLGLIVIDYLQLMSG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 410 GKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPDSQEADHER 489
Cdd:TIGR00665 319 SGRSENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYYNPDSED 398
|
410 420 430
....*....|....*....|....*....|....
gi 896153470 490 AGEADIIVAKHRGGPTGSIAVAHQLHYSRFANLA 523
Cdd:TIGR00665 399 KGIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
93-523 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 647.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 93 NIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLYLHTL 172
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 173 ASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAgaEDTEPEQLVDEAQQLIFSVGRENTKNDYVPIADVLDDTL 252
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAYD--EDEDVDELLDEAEQKIFEIAEKRSSKGFVSISDILKEAL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 253 EELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSLEMSRNEIMMR 332
Cdd:COG0305 159 ERIEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGKPVAIFSLEMSAEQLVMR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 333 IMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQLKQKHDLKMIVVDYLQLMSSGKK 412
Cdd:COG0305 239 LLSSEARIDSSKLRTGKLSDEDWERLSSAAGELSEAPIYIDDTPGLTIAEIRAKARRLKREHGLGLIVIDYLQLMSGSGR 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 413 VESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPDSQEADHERAGE 492
Cdd:COG0305 319 SENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNPDSEDKGI 398
|
410 420 430
....*....|....*....|....*....|.
gi 896153470 493 ADIIVAKHRGGPTGSIAVAHQLHYSRFANLA 523
Cdd:COG0305 399 AEIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
71-475 |
0e+00 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 560.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 71 DRGRGARASAvAGATFERTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILL 150
Cdd:PRK07773 6 DLAPGMDSSP-PSEDYGRQPPQDLAAEQSVLGGMLLSKEAIARVLERLRPGAFYRPAHQNIYDAILDLYGRGEPADLVTV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 151 AGRLDRTGDLERIGGPLYLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAgaEDTEPEQLVDEAQQLIF 230
Cdd:PRK07773 85 AAELDRRGLLERIGGAPYLHTLISTVPTAANADYYARIVAEKALLRRLIEAGTRIVQYGYA--EGADVAEVVDRAQAEIY 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 231 SVGRENTKNDYVPIADVLDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSAS 310
Cdd:PRK07773 163 DVTDRRLSEDFVALEDLLQPTFDEIDAIASSGGLARGVPTGFTELDAMTNGLHPGQLIIVAARPSMGKTTFGLDFARNCA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 311 IRNGMTSAIFSLEMSRNEIMMRIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQL 390
Cdd:PRK07773 243 IRHRLAVAIFSLEMSKEQLVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARAMGEISEAPIFIDDTPNLTVMEIRAKARRL 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 391 KQKHDLKMIVVDYLQLMSSGKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQD 470
Cdd:PRK07773 323 RQEANLGLIVVDYLQLMTSGKKYENRQQEVSEISRHLKLLAKELEVPVVALSQLSRGVEQRTDKRPMLSDLRESGCLTGD 402
|
....*
gi 896153470 471 ADIVM 475
Cdd:PRK07773 403 TLILR 407
|
|
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
86-523 |
5.95e-178 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 508.34 E-value: 5.95e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 86 FERTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGG 165
Cdd:PRK05748 6 ALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDLEEVGG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 166 PLYLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDtePEQLVDEAQQLIFSVGRENTKNDYVPIA 245
Cdd:PRK05748 86 LSYLAELANSVPTAANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPEDD--ADEILDEAEKKIFEVSERRNKSGFKNIK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 246 DVLDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSLEMS 325
Cdd:PRK05748 164 DVLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDKNVAIFSLEMG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 326 RNEIMMRIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQLKQKH-DLKMIVVDYL 404
Cdd:PRK05748 244 AESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMGSLSDAPIYIDDTPGIKVTEIRARCRRLAQEHgGLGLILIDYL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 405 QLMS-SGKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPDSQ 483
Cdd:PRK05748 324 QLIQgSGRSGENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVAFLYRDDYY 403
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 896153470 484 EADHERAGEADIIVAKHRGGPTGSIAVAHQLHYSRFANLA 523
Cdd:PRK05748 404 DEETENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLA 443
|
|
| PRK05595 |
PRK05595 |
replicative DNA helicase; Provisional |
88-522 |
2.81e-152 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235525 [Multi-domain] Cd Length: 444 Bit Score: 442.73 E-value: 2.81e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 88 RTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPL 167
Cdd:PRK05595 6 RSLPQSIEAEQSVLGAMIIDKTSIAEAAEVLKSEDFYRDSHKVIFSAIIELYQKDIAVDMLTLTENLKSTDKLEAAGGVT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 168 YLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDTEpeQLVDEAQQLIFSVGRENTKNDYVPIADV 247
Cdd:PRK05595 86 YITELSNSIVSTANIQSYIKIVKDKSTLRRLIKSSTEIIENSYNNQDDVE--KVIDSAEKKIFDISEKRTTSDFEPLSNV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 248 LDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSLEMSRN 327
Cdd:PRK05595 164 LERGFEQIENLFNNKGETTGVASGFRELDAKTSGFQKGDMILIAARPSMGKTTFALNIAEYAALREGKSVAIFSLEMSKE 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 328 EIMMRIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQLKQKHDLKMIVVDYLQLM 407
Cdd:PRK05595 244 QLAYKLLCSEANVDMLRLRTGNLEDKDWENIARASGPLAAAKIFIDDTAGVSVMEMRSKCRRLKIEHGIDMILIDYLQLM 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 408 SSGKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPDSQEADH 487
Cdd:PRK05595 324 SGGKGSESRQQEVSEISRSIKALAKEMECPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKET 403
|
410 420 430
....*....|....*....|....*....|....*
gi 896153470 488 ERAGEADIIVAKHRGGPTGSIAVAHQLHYSRFANL 522
Cdd:PRK05595 404 EDKNVAECIIAKQRNGPTGTVKLAWLGQYSKFGNL 438
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
267-521 |
5.42e-150 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 429.53 E-value: 5.42e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 267 GVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSLEMSRNEIMMRIMSAEAKINMASLR 346
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKKPVAIFSLEMSAEQLVMRLLASEAGVDSQKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 347 SGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQLKQKHDLKMIVVDYLQLMSSGKKVESRQQEVSEFSRQ 426
Cdd:pfam03796 81 TGQLTDEDWEKLAKAAGRLSEAPLYIDDTPGLSIAEIRAKARRLKREHGLGLIVIDYLQLMSGGSRGENRQQEISEISRS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 427 LKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPDSQEADhERAGEADIIVAKHRGGPTG 506
Cdd:pfam03796 161 LKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYYNPK-EPEGKAEIIIAKQRNGPTG 239
|
250
....*....|....*
gi 896153470 507 SIAVAHQLHYSRFAN 521
Cdd:pfam03796 240 TVKLAFLGEYTRFEN 254
|
|
| PRK09165 |
PRK09165 |
replicative DNA helicase; Provisional |
88-525 |
2.65e-138 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181676 [Multi-domain] Cd Length: 497 Bit Score: 408.89 E-value: 2.65e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 88 RTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPL 167
Cdd:PRK09165 19 RELPHNIEAEQALLGAILINNRALDRVSDFLKPEHFFEPLHQRIYEAIAKIIRKGKLATPVTLKTFLENDEALGELGGVQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 168 YLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDTEPEQLVDEAQQLIFSVGrENTKND--YVPIA 245
Cdd:PRK09165 99 YLAKLATEAVTIINARDYGRIIYDLALRRELINIGEDVVNNAYDAPVDVAPQEQIEDAEQKLYELA-ETGRYEggFQSFG 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 246 DVLDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMD--------FMRSASI------ 311
Cdd:PRK09165 178 TAITEAVDMANAAFKRDGHLSGISTGLRDLDSKLGGLHPSDLIILAGRPSMGKTALATNiafnaakaYRREAQPdgskka 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 312 RNGMTSAIFSLEMSRNEIMMRIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQLK 391
Cdd:PRK09165 258 VNGGVVGFFSLEMSAEQLATRILSEQSEISSSKIRRGKISEEDFEKLVDASQELQKLPLYIDDTPALSISQLRARARRLK 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 392 QKHDLKMIVVDYLQLM--SSGKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQ 469
Cdd:PRK09165 338 RQHGLDLLVVDYLQLIrgSSKRSSDNRVQEISEITQGLKALAKELNIPVIALSQLSRQVEQRDDKRPQLSDLRESGSIEQ 417
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 896153470 470 DADIVMLIYR---------PDSQEADHER--------AGEADIIVAKHRGGPTGSIAVAHQLHYSRFANLAEE 525
Cdd:PRK09165 418 DADVVMFVYReeyylkrkePREGTPKHEEwqekmekvHNKAEVIIAKQRHGPTGTVKLAFESEFTRFGDLADR 490
|
|
| PRK08760 |
PRK08760 |
replicative DNA helicase; Provisional |
66-530 |
2.04e-136 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181547 [Multi-domain] Cd Length: 476 Bit Score: 403.53 E-value: 2.04e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 66 RDWERDRGRGARASAVAGATFERTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEI 145
Cdd:PRK08760 9 SNRNRDRDDDDYDRPEPRLDQLRVPPHSVEAEQAVLGGLMLAPDALDRVNDQLTENDFYRRDHRLIYRAIRELSEKDRPF 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 146 DPILLAGRLDRTGDLERIGGPLYLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAgAEDTEPEQLVDEA 225
Cdd:PRK08760 89 DAVTLGEWFESQGKLEQVGDGAYLIELASTTPSAANIAAYAEIVRDKAVLRQLIEVGTTIVNDGFQ-PEGRESIELLASA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 226 QQLIFSVGRENTK--NDYVPIADVLDDTLEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAM 303
Cdd:PRK08760 168 EKAVFKIAEAGARgrTDFVAMPGALKDAFEELRNRFENGGNITGLPTGYNDFDAMTAGLQPTDLIILAARPAMGKTTFAL 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 304 DFMRSASIRNGMTSAIFSLEMSRNEIMMRIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEI 383
Cdd:PRK08760 248 NIAEYAAIKSKKGVAVFSMEMSASQLAMRLISSNGRINAQRLRTGALEDEDWARVTGAIKMLKETKIFIDDTPGVSPEVL 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 384 RAKARQLKQKHDLKMIVVDYLQLMSSGKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRE 463
Cdd:PRK08760 328 RSKCRRLKREHDLGLIVIDYLQLMSVPGNSENRATEISEISRSLKGLAKELNVPVIALSQLNRSLETRTDKRPVMADLRE 407
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896153470 464 SGSLEQDADIVMLIYRPDSQEADHE-RAGEADIIVAKHRGGPTGSIAVAHQLHYSRFANLAEEPSGSL 530
Cdd:PRK08760 408 SGAIEQDADMIVFIYRDDYYNKENSpDKGLAEIIIGKHRGGPTGSCKLKFFGEYTRFDNLAHDSVGSF 475
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
267-521 |
3.56e-132 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 384.17 E-value: 3.56e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 267 GVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSLEMSRNEIMMRIMSAEAKINMASLR 346
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGLPVLFFSLEMSAEQLAERLLSSESGVSLSKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 347 SGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQLKQKH-DLKMIVVDYLQLMSSGKKVESRQQEVSEFSR 425
Cdd:cd00984 81 TGRLDDEDWERLTAAMGELSELPLYIDDTPGLTVDEIRAKARRLKREHgGLGLIVIDYLQLIRGSKRAENRQQEVAEISR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 426 QLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPDSQEADHERAGEADIIVAKHRGGPT 505
Cdd:cd00984 161 SLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDKDSEDKGIAEIIIAKNRNGPT 240
|
250
....*....|....*.
gi 896153470 506 GSIAVAHQLHYSRFAN 521
Cdd:cd00984 241 GTVYLAFNPEYTRFTD 256
|
|
| phage_DnaB |
TIGR03600 |
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or ... |
93-512 |
2.81e-127 |
|
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions]
Pssm-ID: 274672 [Multi-domain] Cd Length: 420 Bit Score: 378.28 E-value: 2.81e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 93 NIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLYLHTL 172
Cdd:TIGR03600 1 SIEAEQAVLGGLLLDNDFIERVMAILKPEHFYSQDHRIIFEAMLDMFAENRPVDPLTLADKLEAEGEAEKVGGLAYLAEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 173 ASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAgAEDTEPEQLVDEAQQLIFSVGR-ENTKNDYVPIADVLDDT 251
Cdd:TIGR03600 81 SNNTPSAANISSYARIVREKAKERKLIAACQRIITLACS-PDGGTAEQKVEEAQAALLALTMsDGQEDGFVTFGEVLEDV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 252 LEELDLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSLEMSRNEIMM 331
Cdd:TIGR03600 160 VRDLDKRFNPKGELTGLSTGLPKLDRLTNGLVKGDLIVIGARPSMGKTTLALNIAENVALREGKPVLFFSLEMSAEQLGE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 332 RIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQLKQKHD-LKMIVVDYLQLMSSG 410
Cdd:TIGR03600 240 RLLASKSGINTGNIRTGRFNDSEFNRLLNAVDRLSEKDLYIDDTGGLTVAQIRSIARRIKRKKGgLDLIVVDYIQLMAPA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 411 KKvESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPDSQEADHERA 490
Cdd:TIGR03600 320 RG-RDRNEELGGISRGLKALAKELDVPVVLLAQLNRGSEKRTDKRPIMSDLRDSGAIEQDADVIGLIHREGYYDAREPPA 398
|
410 420
....*....|....*....|..
gi 896153470 491 GEADIIVAKHRGGPTGSIAVAH 512
Cdd:TIGR03600 399 GIAELILAKNRHGPTGTVELLF 420
|
|
| PRK06904 |
PRK06904 |
replicative DNA helicase; Validated |
90-526 |
3.80e-121 |
|
replicative DNA helicase; Validated
Pssm-ID: 136106 [Multi-domain] Cd Length: 472 Bit Score: 364.32 E-value: 3.80e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 90 PPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLYL 169
Cdd:PRK06904 23 PPHSIEAEQAVLGGIMLDNRHWDSVAERVIADDFYTFEHRIIFQEMELLFRQNTPIDLLTLDQALKTKGKSDEVGGFAYL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 170 HTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAgAEDTEPEQLVDEAQQLIFSVGRENTKNDYVP--IADV 247
Cdd:PRK06904 103 AELSNNTPSAANILAYADIVREKAILRELISVGNNIAKNAYS-PKGQDIKDILDEAERDVFSIAEKRTTANEGPqnVINL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 248 LDDTLEELDLITQ---NGGLAqGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSLEM 324
Cdd:PRK06904 182 LENTIDKIENLAAtptNNGVT-GVTTGFTDLDKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMASEKPVLVFSLEM 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 325 SRNEIMMRIMSAEAKINMASLRSG-DLDERDWTKLVEVGDKIRDAP-LFIDDSPNLTMMEIRAKARQL-KQKHDLKMIVV 401
Cdd:PRK06904 261 PAEQIMMRMLASLSRVDQTKIRTGqNLDQQDWAKISSTVGMFKQKPnLYIDDSSGLTPTELRSRARRVyRENGGLSLIMV 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 402 DYLQLMSSGKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPD 481
Cdd:PRK06904 341 DYLQLMRAPGFEDNRTLEIAEISRSLKALAKELKVPVVALSQLNRTLENRGDKRPVNSDLRESGSIEQDADLIMFIYRDE 420
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 896153470 482 S-QEADHERAGEADIIVAKHRGGPTGSIAVAHQLHYSRFANLAEEP 526
Cdd:PRK06904 421 VyNETTEDNKGVAEIIIGKQRNGPIGRVRLAFQGQYSRFDNLANIP 466
|
|
| PRK08840 |
PRK08840 |
replicative DNA helicase; Provisional |
88-523 |
2.58e-120 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181562 [Multi-domain] Cd Length: 464 Bit Score: 362.00 E-value: 2.58e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 88 RTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPL 167
Cdd:PRK08840 18 KVPPHSLEAEQSVIGGLLLDNERWDTVAEKVVASDFYSRPHRLIFEGVKSILEAGKPLDLITLSEHLERREQLEDVGGFA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 168 YLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYaGAEDTEPEQLVDEAQQLIFSVGRENTKNDYVP--IA 245
Cdd:PRK08840 98 YLADLAKNTPSAANINAYADIVAERALVRNLIGVANEIADAGY-DPQGRTSEDLLDMAESKVFAIAEARTSENEGPqnVD 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 246 DVLDDTLEELDLI---TQNGglAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSL 322
Cdd:PRK08840 177 SILEKTLERIELLyktPQDG--VTGVDTGFTDLNKKTAGLQGSDLIIVAARPSMGKTTFAMNLCENAAMDQDKPVLIFSL 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 323 EMSRNEIMMRIMSAEAKINMASLRSGDLDERDWTKLVE-VGDKIRDAPLFIDDSPNLTMMEIRAKARQLKQKHD-LKMIV 400
Cdd:PRK08840 255 EMPAEQLMMRMLASLSRVDQTKIRTGQLDDEDWARISStMGILMEKKNMYIDDSSGLTPTEVRSRARRIAREHGgLSMIM 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 401 VDYLQLMSSGKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRP 480
Cdd:PRK08840 335 VDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRD 414
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 896153470 481 DSQEADHERAGEADIIVAKHRGGPTGSIAVAHQLHYSRFANLA 523
Cdd:PRK08840 415 EVYNPDSPLKGTAEIIIGKQRNGPIGSVRLTFQGQYSRFDNYA 457
|
|
| PRK07004 |
PRK07004 |
replicative DNA helicase; Provisional |
88-527 |
6.07e-119 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235907 [Multi-domain] Cd Length: 460 Bit Score: 358.07 E-value: 6.07e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 88 RTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPL 167
Cdd:PRK07004 13 KVPPHSIEAEQSVLGGLLLDNAAWDRIADFLSQSDFYRYDHRIIFEHIGRLIAATRPADVITVYEALTTSGKAEEVGGLA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 168 YLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAgAEDTEPEQLVDEAQQLIFSVGRENTKND--YVPIA 245
Cdd:PRK07004 93 YLNALAQNTPSAANIRRYAEIVRDRAVLRRLVSVADEISADAFN-PQGKEVRQLLDEAESKVFSIAEEGARGTqgFLEIG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 246 DVLDDTLEELDLI--TQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSLE 323
Cdd:PRK07004 172 PLLTQVVERIDTLyhTANPSDVTGTPTGFVDLDRMTSGMHGGELIIVAGRPSMGKTAFSMNIGEYVAVEYGLPVAVFSME 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 324 MSRNEIMMRIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQL-KQKHDLKMIVVD 402
Cdd:PRK07004 252 MPGTQLAMRMLGSVGRLDQHRMRTGRLTDEDWPKLTHAVQKMSEAQLFIDETGGLNPMELRSRARRLaRQCGKLGLIIID 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 403 YLQLMSSGKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPDS 482
Cdd:PRK07004 332 YLQLMSGSSQGENRATEISEISRSLKSLAKELDVPVIALSQLNRGLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEV 411
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 896153470 483 QEADHERAGEADIIVAKHRGGPTGSIAVAHQLHYSRFANLAEEPS 527
Cdd:PRK07004 412 YNPDSPDKGTAEIIIGKQRNGPIGPVRLTFLGQYTKFDNFAGAQN 456
|
|
| PRK08506 |
PRK08506 |
replicative DNA helicase; Provisional |
92-526 |
1.25e-118 |
|
replicative DNA helicase; Provisional
Pssm-ID: 236278 [Multi-domain] Cd Length: 472 Bit Score: 357.78 E-value: 1.25e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 92 HNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTgdlERIGGPLYLHT 171
Cdd:PRK08506 5 YDLDIERAVLSSILFSPDKFEEIASVLEPKDFYLPAHQDIFEAMLKLHNEDEPIDEEFIRKKLPKD---KKIDEEILLEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 172 LASlvPTAANAQFYARIVAEKATIRRLVEAGTKIAQIgyAGAEDTEPEQLVDEAQQLIFSVGRENTKNDYVPIADVLDDT 251
Cdd:PRK08506 82 LAT--NPIDNIEAYVEEIKEKSIKRELLSLANTIPEQ--AVEEDQKSSDILDEVERELYSITNGSNSEDFKDSKEVIEST 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 252 LEEL-DLITQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSAsIRNGMTSAIFSLEMSRNEIM 330
Cdd:PRK08506 158 MEHIkKQKRLGNKDIIGLDTGFVELNKMTKGFNKGDLIIIAARPSMGKTTLCLNMALKA-LNQDKGVAFFSLEMPAEQLM 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 331 MRIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQLKQKH-DLKMIVVDYLQLMSS 409
Cdd:PRK08506 237 LRMLSAKTSIPLQNLRTGDLDDDEWERLSDACDELSKKKLFVYDSGYVNIHQVRAQLRKLKSQHpEIGLAVIDYLQLMSG 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 410 GKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPD--SQEADH 487
Cdd:PRK08506 317 SGNFKDRHLQISEISRGLKLLARELDIPIIALSQLNRSLESRADKRPMLSDLRESGAIEQDADIILFVYRDDvyKEREEK 396
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 896153470 488 ERAG--------------------EADIIVAKHRGGPTGSIAVAHQLHYSRFANLAEEP 526
Cdd:PRK08506 397 EKEKkakkegkeerrihfqnksieEAEIIIGKNRNGPTGTVKLRFQKEFTRFVDKPIES 455
|
|
| PRK08006 |
PRK08006 |
replicative DNA helicase DnaB; |
88-523 |
2.16e-117 |
|
replicative DNA helicase DnaB;
Pssm-ID: 181193 [Multi-domain] Cd Length: 471 Bit Score: 354.70 E-value: 2.16e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 88 RTPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPL 167
Cdd:PRK08006 25 KVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 168 YLHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYaGAEDTEPEQLVDEAQQLIFSVGRENTKNDYVP--IA 245
Cdd:PRK08006 105 YLAELSKNTPSAANISAYADIVRERAVVREMISVANEIADAGY-DPQGRTSEDLLDLAESRVFQIAESRANKDEGPknIA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 246 DVLDDTLEELDLITQ--NGGLAqGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSLE 323
Cdd:PRK08006 184 DILDATVARIEQLFQqpHDGVT-GVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMLQDKPVLIFSLE 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 324 MSRNEIMMRIMSAEAKINMASLRSGDLDERDWTKLVE-VGDKIRDAPLFIDDSPNLTMMEIRAKARQLKQKHD-LKMIVV 401
Cdd:PRK08006 263 MPGEQIMMRMLASLSRVDQTRIRTGQLDDEDWARISGtMGILLEKRNMYIDDSSGLTPTEVRSRARRIFREHGgLSLIMI 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 402 DYLQLMSSGKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPD 481
Cdd:PRK08006 343 DYLQLMRVPSLSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDE 422
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 896153470 482 SQEADHERAGEADIIVAKHRGGPTGSIAVAHQLHYSRFANLA 523
Cdd:PRK08006 423 VYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYA 464
|
|
| PRK06321 |
PRK06321 |
replicative DNA helicase; Provisional |
89-523 |
2.07e-104 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180528 [Multi-domain] Cd Length: 472 Bit Score: 321.41 E-value: 2.07e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 89 TPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLY 168
Cdd:PRK06321 15 SPPNSKESEMIVLGCMLTSVNYLNLAANQLQEDDFYFLEHKIIFRVLQDAFKSDKPIDVHLAGEELKRRNQLNVIGGPSY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 169 LHTLASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQigYAGAEDTEPEQLVDEAQQLIFSVGRENTKNDYVPIADVL 248
Cdd:PRK06321 95 LITLAEFAGTSAYIEEYAEIIRSKSILRKMIQTAKEIEK--KALEEPKDVATALDEAQNLLFKISQTTNLAQYVLVADKL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 249 DDTLEELDLI-----------------TQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASI 311
Cdd:PRK06321 173 KGLTSSKDKPfllqlqerqeafqqsaqGDSSPMISGIPTHFIDLDKMINGFSPSNLMILAARPAMGKTALALNIAENFCF 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 312 RNGMTSAIFSLEMSRNEIMMRIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQLK 391
Cdd:PRK06321 253 QNRLPVGIFSLEMTVDQLIHRIICSRSEVESKKISVGDLSGRDFQRIVSVVNEMQEHTLLIDDQPGLKITDLRARARRMK 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 392 QKHDLKMIVVDYLQLMSSG---KKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLE 468
Cdd:PRK06321 333 ESYDIQFLIIDYLQLLSGSgnlRNSESRQTEISEISRMLKNLARELNIPILCLSQLSRKVEDRANHRPMMSDLRESGSIE 412
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 896153470 469 QDADIVMLIYRPDSQEADhERAGEADIIVAKHRGGPTGSIAVAHQLHYSRFANLA 523
Cdd:PRK06321 413 QDSDLVMFLLRREYYDPN-DKPGTAELIVAKNRHGSIGSVPLVFEKEFARFRNYA 466
|
|
| PRK06749 |
PRK06749 |
replicative DNA helicase; Provisional |
93-522 |
8.08e-90 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168658 [Multi-domain] Cd Length: 428 Bit Score: 282.22 E-value: 8.08e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 93 NIEAEQSVLGAMLLNSEVVADVyeQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGdLERIGGPLYLHTL 172
Cdd:PRK06749 5 NVEAEKTVLGSLLLDGELIKEC--RLTEQYFSMPVHKSIFQLMRKMEDEGQPIDLVTFTSRVDPNF-LKGIGGMEYFIGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 173 ASLVPTAANAQFYARIVAEKATIRRLVEAGTKIAQIGYAGAEDTEPEQLVDEAQQLifsvgRENTKNDYVPIADVLDDTL 252
Cdd:PRK06749 82 MDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITALCEL-----EEKDCVCEFDLKDALVDLY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 253 EELDlitQNGGLAQGVPTGITNLDKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASiRNGMTSAIFSLEMSRNEIMMR 332
Cdd:PRK06749 157 EELH---QDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAA-KSGAAVGLFSLEMSSKQLLKR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 333 IMSAEAKINMASLRSGD--LDERDWTKLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQLKQKHDLK--MIVVDYLQLMS 408
Cdd:PRK06749 233 MASCVGEVSGGRLKNPKhrFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKkiLIIVDYLQLIT 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 409 SGKKVE-SRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLRESGSLEQDADIVMLIYRPDSQEADH 487
Cdd:PRK06749 313 GDPKHKgNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKET 392
|
410 420 430
....*....|....*....|....*....|....*
gi 896153470 488 ERAGEADIIVAKHRGGPTGSIAVAHQLHYSRFANL 522
Cdd:PRK06749 393 MQKEMTEIHVAKHRNGPVGSFKLRFLKEFGRFVEG 427
|
|
| DnaB |
pfam00772 |
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
89-191 |
1.48e-39 |
|
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.
Pssm-ID: 395624 [Multi-domain] Cd Length: 103 Bit Score: 138.91 E-value: 1.48e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 89 TPPHNIEAEQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIDPILLAGRLDRTGDLERIGGPLY 168
Cdd:pfam00772 1 VPPHNIEAEQAVLGALLLDPEAIDEVADILKPEDFYDPAHRLIFEAILDLYDKGEPIDPVTVAEELEKKGKLEDVGGIAY 80
|
90 100
....*....|....*....|...
gi 896153470 169 LHTLASLVPTAANAQFYARIVAE 191
Cdd:pfam00772 81 LAELAANVPSAANIEYYARIVKE 103
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
466-523 |
1.76e-21 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 98.67 E-value: 1.76e-21
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 896153470 466 SLEQDADIVMLIYRPDSQEADHERAGEADIIVAKHRGGPTGSIAVAHQLHYSRFANLA 523
Cdd:PRK07773 827 SIEQDADVVILLYRPDYYDRDDPRGGEAEFIVAKHRNGPTGTVTLAFQLHLSRFANLA 884
|
|
| RecA-like_Gp4D_helicase |
cd19483 |
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the ... |
288-518 |
1.05e-19 |
|
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the RecA-like domain of the Gp4D fragment of the Gene4 helicase-primase (Gp4) from bacteriophage T7. Gp4D (residues 241-566) is the minimal fragment of the Gp4 that forms hexameric rings, it contains the helicase domain and the linker connecting the helicase and primase domains. Helicases are ring-shaped oligomeric enzymes that unwind DNA at the replication fork; they couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands. This family belongs to the RecA-like NTPase superfamily which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410891 [Multi-domain] Cd Length: 231 Bit Score: 88.01 E-value: 1.05e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 288 VIIAARPGVGKSTLAMDFMRSASIRNGMTSAIFSLEMSRNEIMMRIMSAEAKINMASLRSGDLDERDWTKLVEVGDKIRD 367
Cdd:cd19483 1 VTIGAGSGIGKSTIVRELAYHLITEHGEKVGIISLEESVEETAKGLAGKHLGKPEPLELPRDDITEEEEDDAFDNELGSG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 368 APLFIDDSPNLTMMEIRAKARQLKQKHDLKMIVVDYLQLMSSGKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQLNR- 446
Cdd:cd19483 81 RFFLYDHFGSLDWDNLKEKIRYMVKVLGCKVIVLDHLTILVSGLDSSDERKELDEIMTELAALVKELGVTIILVSHLRRp 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896153470 447 --GPEARTDKKPQVSDLRESGSLEQDADIVMLIYRpDSQEADHERAGEADIIVAKHRGgpTGSIAVAHQLHYSR 518
Cdd:cd19483 161 ggGKGHEEGGEVSESDLRGSSAIAQLSDYVIGLER-NKQADDPVERNTTRVRVLKNRF--TGETGIAGTLYYDE 231
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
268-504 |
3.24e-16 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 77.65 E-value: 3.24e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 268 VPTGITNLDKLTN-GLHPGQMVIIAARPGVGKSTLAMDFMrSASIRNGMTSAIFSLEMSRNEIMMRIMSaeakINMaslr 346
Cdd:COG0467 2 VPTGIPGLDELLGgGLPRGSSTLLSGPPGTGKTTLALQFL-AEGLRRGEKGLYVSFEESPEQLLRRAES----LGL---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 347 sgdlderDWTKLVEVGD-KIRDA-PLFIDDSPNltmmEIRAKARQLKQKHDLKMIVVD----YLQLMSSgkkvesrQQEV 420
Cdd:COG0467 73 -------DLEEYIESGLlRIIDLsPEELGLDLE----ELLARLREAVEEFGAKRVVIDslsgLLLALPD-------PERL 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 421 SEFSRQLKLLAKELEVPLIAISQLNRGPEARTDkkpqvsdlresGSLEQDAD-IVMLIYRPDSQEAdhERAgeadIIVAK 499
Cdd:COG0467 135 REFLHRLLRYLKKRGVTTLLTSETGGLEDEATE-----------GGLSYLADgVILLRYVELGGEL--RRA----LSVLK 197
|
....*
gi 896153470 500 HRGGP 504
Cdd:COG0467 198 MRGSA 202
|
|
| PRK05973 |
PRK05973 |
replicative DNA helicase; Provisional |
253-462 |
1.07e-13 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168322 [Multi-domain] Cd Length: 237 Bit Score: 70.83 E-value: 1.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 253 EELDLITQNGG----------LAQGVPTGitnldKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSAsIRNGMTSAIFSL 322
Cdd:PRK05973 27 EALDRIAAEEGfsswsllaakAAATTPAE-----ELFSQLKPGDLVLLGARPGHGKTLLGLELAVEA-MKSGRTGVFFTL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 323 EMSRNEIMMRimsaeakinmasLRSGDLDERDWtklvevgdkirdAPLFIDDSPNltmmEIRAK--ARQLKQKHDLKMIV 400
Cdd:PRK05973 101 EYTEQDVRDR------------LRALGADRAQF------------ADLFEFDTSD----AICADyiIARLASAPRGTLVV 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 896153470 401 VDYLQLMSSGKKVESRQQEVsefsRQLKLLAKELEVPLIAISQLNRGPEARTDKKPQVSDLR 462
Cdd:PRK05973 153 IDYLQLLDQRREKPDLSVQV----RALKSFARERGLIIVFISQIDRSFDPSAKPLPDIRDVR 210
|
|
| 41 |
PHA02542 |
41 helicase; Provisional |
97-485 |
1.71e-10 |
|
41 helicase; Provisional
Pssm-ID: 222864 [Multi-domain] Cd Length: 473 Bit Score: 63.16 E-value: 1.71e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 97 EQSVLGAMLLNSEVVADVYEQLTPEDFYRPAHQTIYSAILHLYGESSEIdPILLAGRLDrtgdLERIGGPLYLH-----T 171
Cdd:PHA02542 2 EETILSNLIFNEDYFRKVWPYLKAEYFESGPEKVIFKLIKKHVNEYNAI-PTIEALSIA----LENRSLSEVTFdgakdL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 172 LASLVPTAANAQFYA----RIVAEKATIRRLVEAgtkiaqIGYAGAEDTEPEQ-------------LVDEAQQLIF--SV 232
Cdd:PHA02542 77 LSSLSDNPEDLDWLVketeKWCQDRAMYNALSKA------IEIQDNADKPLEKrnkklpdvgaipdIMQEALAISFdsSV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 233 GrentkNDYvpiadvLDDTLEELDLITQNgglAQGVPTGITNLDKLTNG-LHPGQMVIIAARPGVGKStLAMDFMRSASI 311
Cdd:PHA02542 151 G-----HDY------FEDYEERYDSYQSK---ANKIPFKLEILNKITKGgAERKTLNVLLAGVNVGKS-LGLCSLAADYL 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 312 RNGMTSAIFSLEMSRNEIMMRIMSAEAKINMASLRsgDLDERDWTKLVEVGDKIRDAPLFIDDSP----NLTmmEIRAKA 387
Cdd:PHA02542 216 QQGYNVLYISMEMAEEVIAKRIDANLLDVSLDDID--DLSKAEYKAKMEKLRSKTQGKLIIKQYPtggaHAG--HFRALL 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 388 RQLKQKHDLK--MIVVDYLQLMSSgkkveSRQQEVSEFS--------RQLKLLAKELEVPLIAISQLNRGPEARTDkkPQ 457
Cdd:PHA02542 292 NELKLKKNFKpdVIIVDYLGICAS-----SRLRVSSENSytyvkaiaEELRGLAVEHDVVVWTAAQTTRSGWDSSD--VD 364
|
410 420
....*....|....*....|....*...
gi 896153470 458 VSDLRESGSLEQDADIVMLIYRPDSQEA 485
Cdd:PHA02542 365 MSDTAESAGLPATADFMLAVIETEELAQ 392
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
268-504 |
1.38e-09 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 58.43 E-value: 1.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 268 VPTGITNLDKLTN-GLHPGQMVIIAARPGVGKSTLAMDFMRSAsIRNGMTSAIFSLEMSRNEImmrimsaeaKINMASLr 346
Cdd:cd01124 1 VKTGIPGLDELLGgGIPKGSVTLLTGGPGTGKTLFGLQFLYAG-AKNGEPGLFFTFEESPERL---------LRNAKSF- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 347 sgdldERDWTKLVEVGDkirdapLFIDDSPNLTMM-----EIRAKARQLKQKHDLKMIVVDYLQLMSSGKKVESRQQevs 421
Cdd:cd01124 70 -----GWDFDEMEDEGK------LIIVDAPPTEAGrfsldELLSRILSIIKSFKAKRVVIDSLSGLRRAKEDQMRAR--- 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 422 EFSRQLKLLAKELEVPLIAISQLnRGPEARTDKKPqvsdlresGSLEQDADIVMLIYRpdsQEADHERagEADIIVAKHR 501
Cdd:cd01124 136 RIVIALLNELRAAGVTTIFTSEM-RSFLSSESAGG--------GDVSFIVDGVILLRY---VEIEGEL--RRTIRVLKMR 201
|
...
gi 896153470 502 GGP 504
Cdd:cd01124 202 GTG 204
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
285-505 |
1.06e-08 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 56.83 E-value: 1.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 285 GQMVIIAARPGVGKSTLAMDFmrSASIRNGM----------TSAIFSLEMSRNEIMMRIMSAEAKINMAslrsgdlderd 354
Cdd:COG3598 13 GGVTLLAGPPGTGKSFLALQL--AAAVAAGGpwlgrrvppgKVLYLAAEDDRGELRRRLKALGADLGLP----------- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 355 wtkLVEVGDKIRDAPLFIDDSPNLTMMEIRAKARQlkqkHDLKMIVVDYLQLMSSGKkvESRQQEVSEFSRQLKLLAKEL 434
Cdd:COG3598 80 ---FADLDGRLRLLSLAGDLDDTDDLEALERAIEE----EGPDLVVIDPLARVFGGD--ENDAEEMRAFLNPLDRLAERT 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896153470 435 EVPLIAISQLNRGpearTDKKPQVSDLRESGSLEQDADIVMLIYRPDSQEADHerageadIIVAKHRGGPT 505
Cdd:COG3598 151 GAAVLLVHHTGKG----GAGKDSGDRARGSSALRGAARSVLVLSREKGEDLRV-------LTRAKSNYGPE 210
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
267-449 |
5.77e-08 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 53.15 E-value: 5.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 267 GVPTGITNLDKLTNGLHP-GQMVIIAARPGVGKSTLAMDFMRSAS-------IRNGMTSA---IFSLEMSRNEIMMRIMS 335
Cdd:pfam13481 14 GLAAPPPPRRWLIKGLLPaGGLGLLAGAPGTGKTTLALDLAAAVAtgkpwlgGPRVPEQGkvlYVSAEGPADELRRRLRA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 336 AEAkinmaslrsgDLDERDWTKLVEVGDKIrdaPLFIDDSPNLTMME-IRAKARQLKQKHDLKMIVVDYLQLMSSGkkVE 414
Cdd:pfam13481 94 AGA----------DLDLPARLLFLSLVESL---PLFFLDRGGPLLDAdVDALEAALEEVEDPDLVVIDPLARALGG--DE 158
|
170 180 190
....*....|....*....|....*....|....*
gi 896153470 415 SRQQEVSEFSRQLKLLAKELEVPLIAISQLNRGPE 449
Cdd:pfam13481 159 NSNSDVGRLVKALDRLARRTGATVLLVHHVGKDGA 193
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
268-332 |
8.69e-05 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 44.44 E-value: 8.69e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896153470 268 VPTGITNLDK-LTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASiRNGMTSAIFSLEMSRNEIMMR 332
Cdd:cd01121 64 ISTGIGELDRvLGGGLVPGSVVLIGGDPGIGKSTLLLQVAARLA-QRGGKVLYVSGEESLSQIKLR 128
|
|
| KaiC-like_C |
cd19487 |
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ... |
268-326 |
2.40e-04 |
|
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410895 [Multi-domain] Cd Length: 219 Bit Score: 42.67 E-value: 2.40e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 268 VPTGITNLDKLTNG-LHPGQMVIIAARPGVGKSTLAMDFMRSASIRnGMTSAIFSLEMSR 326
Cdd:cd19487 1 VSSGVPELDELLGGgLERGTSTLLIGPAGVGKSTLALQFAKAAAAR-GERSVLFSFDESI 59
|
|
| KaiC-like_N |
cd19488 |
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ... |
270-329 |
2.46e-04 |
|
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410896 [Multi-domain] Cd Length: 225 Bit Score: 42.72 E-value: 2.46e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896153470 270 TGITNLDK-LTNGLHPGQMVIIAARPGVGKSTLAMDFMRsASIRNGMTSAIFSLEMSRNEI 329
Cdd:cd19488 3 TGIPGLDDiLRGGLPPRRLYLVEGAPGTGKTTLALQFLL-EGAANGETGLYITLSETEQEL 62
|
|
| Sms |
COG1066 |
DNA repair protein RadA/Sms, contains AAA+ ATPase domain [Replication, recombination and ... |
268-301 |
2.82e-04 |
|
DNA repair protein RadA/Sms, contains AAA+ ATPase domain [Replication, recombination and repair];
Pssm-ID: 440685 [Multi-domain] Cd Length: 453 Bit Score: 43.50 E-value: 2.82e-04
10 20 30
....*....|....*....|....*....|....*
gi 896153470 268 VPTGITNLDK-LTNGLHPGQMVIIAARPGVGKSTL 301
Cdd:COG1066 71 ISTGIGELDRvLGGGLVPGSVVLIGGEPGIGKSTL 105
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
284-448 |
9.54e-04 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 39.66 E-value: 9.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 284 PGQMVIIAARPGVGKSTLAMDFMRsasirngmtsaifslEMSRNEIMMRIMSAEAKINMASLRSGDLDERDWTKLVEVGD 363
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALAR---------------ELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGSGEL 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 364 KIRDAplfiddspnltmmeiRAKARqlkqKHDLKMIVVDYLQLMSsgKKVESRQQEVSEFSRQLKLLAKELEVPLIAISQ 443
Cdd:smart00382 66 RLRLA---------------LALAR----KLKPDVLILDEITSLL--DAEQEALLLLLEELRLLLLLKSEKNLTVILTTN 124
|
....*
gi 896153470 444 LNRGP 448
Cdd:smart00382 125 DEKDL 129
|
|
| PRK09302 |
PRK09302 |
circadian clock protein KaiC; Reviewed |
268-330 |
1.68e-03 |
|
circadian clock protein KaiC; Reviewed
Pssm-ID: 236461 [Multi-domain] Cd Length: 509 Bit Score: 41.02 E-value: 1.68e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896153470 268 VPTGITNLDK-LTNGLHPGQMVIIAARPGVGKSTLAMDFMRSAsIRNGMTSAIFSLEMSRNEIM 330
Cdd:PRK09302 255 ISSGVPDLDEmLGGGFFRGSIILVSGATGTGKTLLASKFAEAA-CRRGERCLLFAFEESRAQLI 317
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
276-448 |
1.98e-03 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 40.00 E-value: 1.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 276 DKLTNGLHPGQMVIIAARPGVGKSTLAMDFMRSASIRNGM-----------TSAIFSLEMSRNEIMMRIMSAEAKINMAS 344
Cdd:cd19493 2 TALAGGLPLGAITEITGASGSGKTQFALTLASSAAMPARKggldggvlyidTESKFSAERLAEIAEARFPEAFSGFMEEN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 345 LRSGDLDERdwtklVEVgDKIRDAPLFIDDSPNL--TMMEirakarqlkqkHDLKMIVVDYLQLMS------SGKKVESR 416
Cdd:cd19493 82 ERAEEMLKR-----VAV-VRVTTLAQLLERLPNLeeHILS-----------SGVRLVVIDSIAALVrrefggSDGEVTER 144
|
170 180 190
....*....|....*....|....*....|..
gi 896153470 417 QQEVSEFSRQLKLLAKELEVPLIAISQLNRGP 448
Cdd:cd19493 145 HNALAREASSLKRLAEEFRIAVLVTNQATTHF 176
|
|
| Twinkle_C |
cd01122 |
C-terminal domain of Twinkle; Twinkle ( T7 gp4-like protein with intramitochondrial nucleoid ... |
242-425 |
6.80e-03 |
|
C-terminal domain of Twinkle; Twinkle ( T7 gp4-like protein with intramitochondrial nucleoid localization, also known as C10orf2, PEO1, SCA8, ATXN8, IOSCA, PEOA3 or SANDO) is a homohexameric DNA helicases which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. Mutations in the human gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. This group also contains viral GP4-like and related bacterial helicases.
Pssm-ID: 410867 Cd Length: 266 Bit Score: 38.37 E-value: 6.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 242 VPIADVLDDTLEELdlitQNGGLAQGVP-TGITNLDKLTNGLHPGQMVIIAARPGVGKST----LAMDFmrsasIRNGMT 316
Cdd:cd01122 3 TTFDDLRELVYEEL----LNSEQVAGVQwKRFPSLNKLLKGHRRGELTIFTGPTGSGKTTflseYSLDL-----CMQGVN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896153470 317 SAIFSLEMsRNEIMMRIMsaeakinMASLRSGDLDERDwTKLVEVGDKIRDAPLFI---DDSPNLTmmEIRAKARQLKQK 393
Cdd:cd01122 74 TLWGSFEI-KNVRLAKTM-------LTQFAGKNLEDNL-REFDEWADKFELLPMYFmkfHGSTDID--EVLDAMEHAVYV 142
|
170 180 190
....*....|....*....|....*....|....*..
gi 896153470 394 HDLKMIVVDYLQLM-----SSGKKVESRQQEVSEFSR 425
Cdd:cd01122 143 YDIQHIVIDNLQFMmgtqaSGSDRFELQDLIIGKFRR 179
|
|
| |
