|
Name |
Accession |
Description |
Interval |
E-value |
| NlpA |
COG1464 |
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion ... |
4-266 |
3.33e-88 |
|
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism];
Pssm-ID: 441073 [Multi-domain] Cd Length: 270 Bit Score: 263.89 E-value: 3.33e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 4 KRFSAGVLTVAfAATGLTACGSSDDA--------IRIGTTDA-GKKAWTVFEQKASEQGIDLDVQPFSDYQTPNRALDEG 74
Cdd:COG1464 2 KKLLALLLALA-LALALAACGSSSAAaaaadkktIKVGATPGpHAEILEVVKPELAKKGIDLEIVEFTDYVQPNEALADG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 75 QLDVNLFQHIKFLAEYNVGAKSDLTPIGSSEIVPLALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQ 154
Cdd:COG1464 81 EIDANYFQHIPYLDNFNKENGYDLVPVGKTHIEPMGLYSKKYKSLDELPDGATIAIPNDPTNQGRALLLLQKAGLIKLKD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 155 DDLLTPSPADIDKEASKITVLPVDAAQTPAAYGEGKPAIINNSFLDRAGIDPNT-AIFQDDPNSteaePYINVFVTKAEN 233
Cdd:COG1464 161 GVGLLATVKDITENPKNLKFVELDAAQLPRSLDDVDAAVINGNYALEAGLDPTKdALFLEDKDS----PYANIIVVREDD 236
|
250 260 270
....*....|....*....|....*....|...
gi 896177604 234 ADNPKYAELSKIWHSKEVQDAVAEDSKGTSVPV 266
Cdd:COG1464 237 KDDPAIKKLVEAYQSDEVKKFIEEKYKGAVVPA 269
|
|
| PBP2_lipoprotein_GmpC |
cd13596 |
The periplasmic substrate-binding domain of the membrane-associated lipoprotein-9 GmpC; ... |
30-257 |
1.05e-70 |
|
The periplasmic substrate-binding domain of the membrane-associated lipoprotein-9 GmpC; contains the type 2 periplasmic-binding protein fold; This group includes the membrane-associated lipoprotein-9 from Staphylococcus aureus that binds the dipeptide glycylmethionine (GlyMet). The lipoprotein-9 has both structural and sequential homology to the MetQ family of substrate-binding protein. The GlyMet binding protein belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270314 Cd Length: 230 Bit Score: 218.00 E-value: 1.05e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 30 IRIGTTDAGKKAWTVFEQKASEQGIDLDVQPFSDYQTPNRALDEGQLDVNLFQHIKFLAEYNVGAKSDLTPIGSSEIVPL 109
Cdd:cd13596 2 VKIGVTGEDTDIWDKIVEEAEEAGIKLELVNFSDYSQPNKALNDGDIDLNAFQHYAYLVQYNSKNNADLTAIGDTVIAPM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 110 ALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQDDLLTPSPADIDKEASKITVLPVDAAQTPAAYGEG 189
Cdd:cd13596 82 GIYSKKITSVDELPDGAKIAIPNDPSNLSRALFILQAAGLIKLKKDAGDFPTVNDITENPKNLEIVPVDADQVYRALNDV 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896177604 190 KPAIINNSFLDRAGIDP-NTAIFQDDPNSTEAEPYINVFVTKAENADNPKYAELSKIWHSKEVQDAVAE 257
Cdd:cd13596 162 DAAVINNTFALDAGLDPkKDAIFLEDPSSYGSKPYINLIAVREEDKDNPLYKKLVETYHDERVQKAVEE 230
|
|
| Lipoprotein_9 |
pfam03180 |
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. ... |
30-266 |
4.70e-60 |
|
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. It contains several antigenic members, that may be involved in bacterial virulence. This entry includes the D-methionine binding lipoprotein MetQ, which is the substrate-binding component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system. Other members of this family, such as NlpA, have been identified as putative substrate-binding components of ABC transporters. NlpA, is an inner-membrane-anchored lipoprotein that has been shown to have a minor role in methionine import.
Pssm-ID: 427184 Cd Length: 236 Bit Score: 190.94 E-value: 4.70e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 30 IRIGTTDAGKKAWTVFEQK-ASEQGIDLDVQPFSDYQTPNRALDEGQLDVNLFQHIKFLAEYNVGAKSDLTPIGSSEIVP 108
Cdd:pfam03180 1 LKVGATPGPHAEILEVAKPlLKKKGLDLEIVEFTDYVQPNTALADGEIDANYFQHLPYLDQFNKEKGLDLVAVGNVHIEP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 109 LALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQDDLLTPSPADIDKEASKITVLPVDAAQTPAAYGE 188
Cdd:pfam03180 81 MGLYSKKYKSLSELPDGATIAVPNDPSNEGRALLLLQKAGLIKLKDGKGLLATVKDITENPKNLKIKELEAAQLPRALDD 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896177604 189 GKPAIINNSFLDRAGIDPNTAIFQDDPNSteaEPYINVFVTKAENADNPKYAELSKIWHSKEVQDAVAEDSKGTSVPV 266
Cdd:pfam03180 161 VDAAVINTNYALEAGLNPKKDALFEEDKD---SPYVNIIVVREDDKDDEAVKKLVEAYQSEEVKKFIEKKYGGAVIPA 235
|
|
| PRK09861 |
PRK09861 |
lipoprotein NlpA; |
5-265 |
2.32e-40 |
|
lipoprotein NlpA;
Pssm-ID: 182119 Cd Length: 272 Bit Score: 141.31 E-value: 2.32e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 5 RFSAGVLTVAFAATGLTACGSSDDAIRIGTTDAGKKAWTVFEQKASEQ--GIDLDVQPFSDYQTPNRALDEGQLDVNLFQ 82
Cdd:PRK09861 9 RAGAALLLAGILLAGCDQSSSDAKHIKVGVINGAEQDVAEVAKKVAKEkyGLDVELVGFSGSLLPNDATNHGELDANVFQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 83 HIKFLAEYNVGAKSDLTPIGSSEIVPLALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQDDLLTPSP 162
Cdd:PRK09861 89 HRPFLEQDNQAHGYKLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITLKEGKGLLPTA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 163 ADIDKEASKITVLPVDAAQTPAAYGEGK--PAIINNSFLDRAGIDP-NTAIFQDDPNSteaePYINVFVTKAENADNPKY 239
Cdd:PRK09861 169 LDITDNPRHLQIMELEGAQLPRVLDDPKvdVAIISTTYIQQTGLSPvHDSVFIEDKNS----PYVNILVAREDNKNAENV 244
|
250 260
....*....|....*....|....*.
gi 896177604 240 AELSKIWHSKEVQDAVAEDSKGTSVP 265
Cdd:PRK09861 245 KEFLQSYQSPEVAKAAETIFNGGAVP 270
|
|
| TIGR00363 |
TIGR00363 |
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for ... |
16-265 |
6.54e-36 |
|
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for lipoprotein signal sequence cleavage. Included in this family is the E. coli hypothetical protein yaeC. About half of the proteins between the noise and trusted cutoffs contain the consensus lipoprotein signature and may belong to this family. [Cell envelope, Other]
Pssm-ID: 129460 Cd Length: 258 Bit Score: 129.25 E-value: 6.54e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 16 AATGLTACG-SSDDA--IRIGTTDAGKKAWTVFEQKASEQGIDLDVQ--PFSDYQTPNRALDEGQLDVNLFQHIKFLAEY 90
Cdd:TIGR00363 3 SALVLTGCKqDKKDPlhIKVGVISGAEQQVAEVAAKVAKEKYGLDVElvEFNDYALPNEAVSKGDLDANAFQHKPYLDQD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 91 NVGAKSDLTPIGSSEIVPLALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQDDLLTPSPADIDKEAS 170
Cdd:TIGR00363 83 AKAKGYKLVAVGNTFVYPLAGYSKKIKNVNELQDGAKVAVPNDPTNLGRALLLLQKQGLIKLKDGNGLLPTVLDIVENPK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 171 KITVLPVDAAQTPAAYGEGKP--AIINNSFLDRAGIDP-NTAIFQDDPNSteaePYINVFVTKAENADNPKYAELSKIWH 247
Cdd:TIGR00363 163 KLNITELETSQLPRALDDPKVdlAVINTTYAGQVGLNPqDDGVFVEDKDS----PYVNIIVSREDNKDAENVKDFIQSYQ 238
|
250
....*....|....*...
gi 896177604 248 SKEVQDAVAEDSKGTSVP 265
Cdd:TIGR00363 239 SEEVYQAAQKHFNGGAVK 256
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| NlpA |
COG1464 |
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion ... |
4-266 |
3.33e-88 |
|
ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism];
Pssm-ID: 441073 [Multi-domain] Cd Length: 270 Bit Score: 263.89 E-value: 3.33e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 4 KRFSAGVLTVAfAATGLTACGSSDDA--------IRIGTTDA-GKKAWTVFEQKASEQGIDLDVQPFSDYQTPNRALDEG 74
Cdd:COG1464 2 KKLLALLLALA-LALALAACGSSSAAaaaadkktIKVGATPGpHAEILEVVKPELAKKGIDLEIVEFTDYVQPNEALADG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 75 QLDVNLFQHIKFLAEYNVGAKSDLTPIGSSEIVPLALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQ 154
Cdd:COG1464 81 EIDANYFQHIPYLDNFNKENGYDLVPVGKTHIEPMGLYSKKYKSLDELPDGATIAIPNDPTNQGRALLLLQKAGLIKLKD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 155 DDLLTPSPADIDKEASKITVLPVDAAQTPAAYGEGKPAIINNSFLDRAGIDPNT-AIFQDDPNSteaePYINVFVTKAEN 233
Cdd:COG1464 161 GVGLLATVKDITENPKNLKFVELDAAQLPRSLDDVDAAVINGNYALEAGLDPTKdALFLEDKDS----PYANIIVVREDD 236
|
250 260 270
....*....|....*....|....*....|...
gi 896177604 234 ADNPKYAELSKIWHSKEVQDAVAEDSKGTSVPV 266
Cdd:COG1464 237 KDDPAIKKLVEAYQSDEVKKFIEEKYKGAVVPA 269
|
|
| PBP2_lipoprotein_GmpC |
cd13596 |
The periplasmic substrate-binding domain of the membrane-associated lipoprotein-9 GmpC; ... |
30-257 |
1.05e-70 |
|
The periplasmic substrate-binding domain of the membrane-associated lipoprotein-9 GmpC; contains the type 2 periplasmic-binding protein fold; This group includes the membrane-associated lipoprotein-9 from Staphylococcus aureus that binds the dipeptide glycylmethionine (GlyMet). The lipoprotein-9 has both structural and sequential homology to the MetQ family of substrate-binding protein. The GlyMet binding protein belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270314 Cd Length: 230 Bit Score: 218.00 E-value: 1.05e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 30 IRIGTTDAGKKAWTVFEQKASEQGIDLDVQPFSDYQTPNRALDEGQLDVNLFQHIKFLAEYNVGAKSDLTPIGSSEIVPL 109
Cdd:cd13596 2 VKIGVTGEDTDIWDKIVEEAEEAGIKLELVNFSDYSQPNKALNDGDIDLNAFQHYAYLVQYNSKNNADLTAIGDTVIAPM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 110 ALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQDDLLTPSPADIDKEASKITVLPVDAAQTPAAYGEG 189
Cdd:cd13596 82 GIYSKKITSVDELPDGAKIAIPNDPSNLSRALFILQAAGLIKLKKDAGDFPTVNDITENPKNLEIVPVDADQVYRALNDV 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896177604 190 KPAIINNSFLDRAGIDP-NTAIFQDDPNSTEAEPYINVFVTKAENADNPKYAELSKIWHSKEVQDAVAE 257
Cdd:cd13596 162 DAAVINNTFALDAGLDPkKDAIFLEDPSSYGSKPYINLIAVREEDKDNPLYKKLVETYHDERVQKAVEE 230
|
|
| Lipoprotein_9 |
pfam03180 |
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. ... |
30-266 |
4.70e-60 |
|
NlpA lipoprotein; This entry represents bacterial lipoproteins that belong to the NlpA family. It contains several antigenic members, that may be involved in bacterial virulence. This entry includes the D-methionine binding lipoprotein MetQ, which is the substrate-binding component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system. Other members of this family, such as NlpA, have been identified as putative substrate-binding components of ABC transporters. NlpA, is an inner-membrane-anchored lipoprotein that has been shown to have a minor role in methionine import.
Pssm-ID: 427184 Cd Length: 236 Bit Score: 190.94 E-value: 4.70e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 30 IRIGTTDAGKKAWTVFEQK-ASEQGIDLDVQPFSDYQTPNRALDEGQLDVNLFQHIKFLAEYNVGAKSDLTPIGSSEIVP 108
Cdd:pfam03180 1 LKVGATPGPHAEILEVAKPlLKKKGLDLEIVEFTDYVQPNTALADGEIDANYFQHLPYLDQFNKEKGLDLVAVGNVHIEP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 109 LALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQDDLLTPSPADIDKEASKITVLPVDAAQTPAAYGE 188
Cdd:pfam03180 81 MGLYSKKYKSLSELPDGATIAVPNDPSNEGRALLLLQKAGLIKLKDGKGLLATVKDITENPKNLKIKELEAAQLPRALDD 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896177604 189 GKPAIINNSFLDRAGIDPNTAIFQDDPNSteaEPYINVFVTKAENADNPKYAELSKIWHSKEVQDAVAEDSKGTSVPV 266
Cdd:pfam03180 161 VDAAVINTNYALEAGLNPKKDALFEEDKD---SPYVNIIVVREDDKDDEAVKKLVEAYQSEEVKKFIEKKYGGAVIPA 235
|
|
| PBP2_lipoprotein_MetQ_like |
cd13526 |
The periplasmic-binding component of ABC-type methionine uptake transporter system and its ... |
30-257 |
1.70e-55 |
|
The periplasmic-binding component of ABC-type methionine uptake transporter system and its related lipoproteins; the type 2 periplasmic-binding protein fold; This family represents the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ) and its related homologs. Members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270244 Cd Length: 228 Bit Score: 179.05 E-value: 1.70e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 30 IRIGTT-DAGKKAWTVFEQKASEQGIDLDVQPFSDYQTPNRALDEGQLDVNLFQHIKFLAEYNVGAKSDLTPIGSSEIVP 108
Cdd:cd13526 2 LKIGVTaGPSADVVEAAKKEAKKKGYELELVVFTDYVAPNEALNDGSIDANFFQHVPFLDQFNKERNGDLVKVGKTVIAP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 109 LALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQDDLLTPSPADIDKEASKITVLPVDAAQTPAAYGE 188
Cdd:cd13526 82 IGLYSKKYKSLDELPDGARIAIPNDPSNGARALLLLEDAGLIKLKDGVGLFATVLDITENPKNLEIVEVDAAQLPRSLDD 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 189 GKPAIINNSFLDRAGIDP-NTAIFQDDpnsTEAEPYINVFVTKAENADNPKYAELSKIWHSKEVQDAVAE 257
Cdd:cd13526 162 VDAAVINGNYAISAGLDPrKDAIFLED---SDASPYVNVLAVREDNKDDPWVKALVEAYQSEEVRKFLKE 228
|
|
| PBP2_lipoprotein_IlpA_like |
cd13598 |
Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus and similar ... |
30-254 |
4.37e-50 |
|
Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus and similar lipoproteins; the type 2 periplasmic binding protein fold; This group includes the IlpA protein which has both structural and sequential homology to the MetQ family of substrate-binding protein, and thus belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270316 Cd Length: 227 Bit Score: 164.83 E-value: 4.37e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 30 IRIGT-TDAGKKAWTVFEQKASEQGIDLDVQPFSDYQTPNRALDEGQLDVNLFQHIKFLAEYNVGAKSDLTPIGSSEIVP 108
Cdd:cd13598 2 IKVGViRGPDAQIWEVVQKVAKEKGLDVELVTFNDYAQPNEALAAGDLDANAFQHKPYLDAQIKARGYKLVIVGNTFVYP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 109 LALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQDDLLTPSPADIDKEASKITVLPVDAAQTPAAYGE 188
Cdd:cd13598 82 IGLYSKKIKSLAELPNGATVAIPNDPSNEGRALLLLQKEGLIKLKDGVGLLATVRDIAENPKKLKIVELDAGQLPRALDD 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 896177604 189 GKPAIINNSFLDRAGIDP-NTAIFQDDPNSteaePYINVFVTKAENADNPKYAELSKIWHSKEVQDA 254
Cdd:cd13598 162 VDLAAINTDYASKAGLTPaRDAIAQEDKRS----PYANVIAVREDDKDAPWVKTLVQAYQSEEVKAF 224
|
|
| PRK09861 |
PRK09861 |
lipoprotein NlpA; |
5-265 |
2.32e-40 |
|
lipoprotein NlpA;
Pssm-ID: 182119 Cd Length: 272 Bit Score: 141.31 E-value: 2.32e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 5 RFSAGVLTVAFAATGLTACGSSDDAIRIGTTDAGKKAWTVFEQKASEQ--GIDLDVQPFSDYQTPNRALDEGQLDVNLFQ 82
Cdd:PRK09861 9 RAGAALLLAGILLAGCDQSSSDAKHIKVGVINGAEQDVAEVAKKVAKEkyGLDVELVGFSGSLLPNDATNHGELDANVFQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 83 HIKFLAEYNVGAKSDLTPIGSSEIVPLALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQDDLLTPSP 162
Cdd:PRK09861 89 HRPFLEQDNQAHGYKLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITLKEGKGLLPTA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 163 ADIDKEASKITVLPVDAAQTPAAYGEGK--PAIINNSFLDRAGIDP-NTAIFQDDPNSteaePYINVFVTKAENADNPKY 239
Cdd:PRK09861 169 LDITDNPRHLQIMELEGAQLPRVLDDPKvdVAIISTTYIQQTGLSPvHDSVFIEDKNS----PYVNILVAREDNKNAENV 244
|
250 260
....*....|....*....|....*.
gi 896177604 240 AELSKIWHSKEVQDAVAEDSKGTSVP 265
Cdd:PRK09861 245 KEFLQSYQSPEVAKAAETIFNGGAVP 270
|
|
| TIGR00363 |
TIGR00363 |
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for ... |
16-265 |
6.54e-36 |
|
lipoprotein, YaeC family; This family of putative lipoproteins contains a consensus site for lipoprotein signal sequence cleavage. Included in this family is the E. coli hypothetical protein yaeC. About half of the proteins between the noise and trusted cutoffs contain the consensus lipoprotein signature and may belong to this family. [Cell envelope, Other]
Pssm-ID: 129460 Cd Length: 258 Bit Score: 129.25 E-value: 6.54e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 16 AATGLTACG-SSDDA--IRIGTTDAGKKAWTVFEQKASEQGIDLDVQ--PFSDYQTPNRALDEGQLDVNLFQHIKFLAEY 90
Cdd:TIGR00363 3 SALVLTGCKqDKKDPlhIKVGVISGAEQQVAEVAAKVAKEKYGLDVElvEFNDYALPNEAVSKGDLDANAFQHKPYLDQD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 91 NVGAKSDLTPIGSSEIVPLALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQDDLLTPSPADIDKEAS 170
Cdd:TIGR00363 83 AKAKGYKLVAVGNTFVYPLAGYSKKIKNVNELQDGAKVAVPNDPTNLGRALLLLQKQGLIKLKDGNGLLPTVLDIVENPK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 171 KITVLPVDAAQTPAAYGEGKP--AIINNSFLDRAGIDP-NTAIFQDDPNSteaePYINVFVTKAENADNPKYAELSKIWH 247
Cdd:TIGR00363 163 KLNITELETSQLPRALDDPKVdlAVINTTYAGQVGLNPqDDGVFVEDKDS----PYVNIIVSREDNKDAENVKDFIQSYQ 238
|
250
....*....|....*...
gi 896177604 248 SKEVQDAVAEDSKGTSVP 265
Cdd:TIGR00363 239 SEEVYQAAQKHFNGGAVK 256
|
|
| PBP2_lipoprotein_Gna1946 |
cd13599 |
The membrane-associated lipoprotein Gna1946 from Neisseria meningitidis; the type 2 ... |
51-257 |
3.37e-35 |
|
The membrane-associated lipoprotein Gna1946 from Neisseria meningitidis; the type 2 periplasmic binding protein fold; Gna1946 shares significant structural and sequence homology with the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ). The members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270317 Cd Length: 228 Bit Score: 126.36 E-value: 3.37e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 51 EQGIDLDVQPFSDYQTPNRALDEGQLDVNLFQHIKFLAEYNVGAKSDLTPIGSSEIVPLALFWKDHKSVDELKKGTEVVI 130
Cdd:cd13599 25 KKGYEVKLKEFTDYVQPNNALANGEIDANVFQHKPYLDAFNKENGLDLVGIVQVPTPPMGLYSNKHKSLEEVKDGATVAI 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 131 PNDPSNQGRAINVLVQAG-LLKLKQDDLLTPSPADIDKEASKITVLPVDAAQTPAAYGEGKPAIINNSFLDRAGIDPNTA 209
Cdd:cd13599 105 PNDPSNLARALVMLQDLGwITLKDNIDPLKASVNDIAENPKNIKIVELEAAQLPRSLDDVDFAAIQGNFAISSGIKLTSA 184
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 896177604 210 IFQDDPNSteaePYINVFVTKAENADNPKYAELSKIWHSKEVQDAVAE 257
Cdd:cd13599 185 LALEEMTD----PYVNVVAVKTADKDKQFAKDVTAAYNSDAFKAYIHA 228
|
|
| metQ |
PRK11063 |
D-methionine ABC transporter substrate-binding protein MetQ; |
1-264 |
2.34e-34 |
|
D-methionine ABC transporter substrate-binding protein MetQ;
Pssm-ID: 182939 [Multi-domain] Cd Length: 271 Bit Score: 125.64 E-value: 2.34e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 1 MNLKRFSAGVLTVAFAATGLTACGSSD---DAIRIGT-TDAGKKAWTVFEQKASEQ-GIDLDVQPFSDYQTPNRALDEGQ 75
Cdd:PRK11063 1 MAFKFKTFAAVGALIGTLALVGCGQDEkdpNHIKVGViVGAEQQVAEVAQKVAKEKyGLDVELVTFNDYVLPNEALSKGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 76 LDVNLFQHIKFLAEYNVGAKSDLTPIGSSEIVPLALFWKDHKSVDELKKGTEVVIPNDPSNQGRAINVLVQAGLLKLKQD 155
Cdd:PRK11063 81 IDANAFQHKPYLDQQIKDRGYKLVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 156 DLLTPSPADIDKEASKITVLPVDAAQTPAAYGEGKP--AIINNSFLDRAGIDP-NTAIFQDDPNSteaePYINVFVTKAE 232
Cdd:PRK11063 161 VGLLPTVLDIVENPKNLKIVELEAPQLPRSLDDAQIalAVINTTYASQIGLTPaKDGIFVEDKDS----PYVNLIVARED 236
|
250 260 270
....*....|....*....|....*....|..
gi 896177604 233 NADNPKYAELSKIWHSKEVQDAVAEDSKGTSV 264
Cdd:PRK11063 237 NKDAENVKKFVQAYQSDEVYEAANKVFNGGAV 268
|
|
| PBP2_lipoprotein_like_1 |
cd13600 |
Putative periplasmic-binding component of ABC-type methionine uptake transporter system-like; ... |
46-252 |
1.36e-29 |
|
Putative periplasmic-binding component of ABC-type methionine uptake transporter system-like; the type 2 periplasmic binding protein fold; This subgroup shares significant sequence homology with the periplasmic substrate-binding domain of ATP-binding cassette (ABC) transporter involved in uptake of methionine (MetQ). The members of the MetQ-like family include the 32-kilodalton lipoprotein (Tp32) from Treponema pallidum, the membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus, and Toll-like receptor 2-activating lipoprotein IlpA from Vibrio vulnificus. They all function as a receptor for methionine. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.
Pssm-ID: 270318 Cd Length: 228 Bit Score: 111.66 E-value: 1.36e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 46 EQKASEQGIDLDVQPFSDYQTPNRALDEGQLDVNLFQHIKFLAEYNVGAKSDLTPIGSSEIVPLALFWKDHKSVDELKKG 125
Cdd:cd13600 19 AAELAPDGITIEPVQVSDYVQANRAVAAGEIDANFFQHQPFMEQFNEANGFELVAVQPIYHWAFGFYSKKYKSVEDLPDG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 126 TEVVIPNDPSNQGRAINVLVQAGLLK-LKQDDLLTPSPADIDKEASKITVLPVDAAQTPAAYGEGKPAIINNSFLDRAGI 204
Cdd:cd13600 99 AKVAIPNDPANQARALLLLQRAGLITlKPGVDPTTATLADIVTNPKNLKFTEVDLLALPRALDDVDLAFGYPSYFDAAGL 178
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 896177604 205 DPNTAIFQDDPnstEAEPYINVFVTKAENADNPKYAELSKIWHSKEVQ 252
Cdd:cd13600 179 TPKDGILLEEP---DAKRFAIQLVAREDNKDSPKIKKLKEAFTDPRVR 223
|
|
| Periplasmic_Binding_Protein_Type_2 |
cd00648 |
Type 2 periplasmic binding fold superfamily; This evolutionary model and hierarchy represent ... |
32-148 |
3.04e-03 |
|
Type 2 periplasmic binding fold superfamily; This evolutionary model and hierarchy represent the ligand-binding domains found in solute binding proteins that serve as initial receptors in the transport, signal transduction and channel gating. The PBP2 proteins share the same architecture as periplasmic binding proteins type 1 (PBP1), but have a different topology. They are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The origin of PBP module can be traced across the distant phyla, including eukaryotes, archebacteria, and prokaryotes. The majority of PBP2 proteins are involved in the uptake of a variety of soluble substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the family includes ionotropic glutamate receptors and unorthodox sensor proteins involved in signal transduction. The substrate binding domain of the LysR transcriptional regulators and the oligopeptide-like transport systems also contain the type 2 periplasmic binding fold and thus they are significantly homologous to that of the PBP2; however, these two families are grouped into a separate hierarchy of the PBP2 superfamily due to the large number of protein sequences.
Pssm-ID: 270214 [Multi-domain] Cd Length: 196 Bit Score: 37.94 E-value: 3.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896177604 32 IGTTDAGKKAWTVFEQKASEQGIDLDVQPFSDYQTPNRALDEGQLDVNLFQHIKFL-AEYNVGAKSDLTPIGSSEIVPLA 110
Cdd:cd00648 7 IGPPPYAGFAEDAAKQLAKETGIKVELVPGSSIGTLIEALAAGDADVAVGPIAPALeAAADKLAPGGLYIVPELYVGGYV 86
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 896177604 111 LF----WKDHKSVDELK-KGTEVVIPNDPSNQGRAINVLVQAG 148
Cdd:cd00648 87 LVvrkgSSIKGLLAVADlDGKRVGVGDPGSTAVRQARLALGAY 129
|
|
| |
