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Conserved domains on  [gi|896182377|ref|WP_049193704|]
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MULTISPECIES: RNA polymerase sigma factor SigE [Corynebacterium]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK09647 super family cl35882
RNA polymerase sigma factor SigE; Reviewed
18-202 6.93e-115

RNA polymerase sigma factor SigE; Reviewed


The actual alignment was detected with superfamily member PRK09647:

Pssm-ID: 236606 [Multi-domain]  Cd Length: 203  Bit Score: 325.97  E-value: 6.93e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  18 DAASADVTEQLSGTAAFDA--GVGEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGTFEGW 95
Cdd:PRK09647   2 DDDWVEPSDELTGTAVFDAtgDKATMPSWEELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSLQNYQPGTFEGW 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  96 LHRITTNLFLDMVRHRQVIRMEALPENYDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIA 175
Cdd:PRK09647  82 LHRITTNLFLDMVRRRARIRMEALPEDYDRVPGDEPNPEQIYHDARLDPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIA 161
                        170       180
                 ....*....|....*....|....*..
gi 896182377 176 STLGLKMGTVRSRIHRARSSLRATLER 202
Cdd:PRK09647 162 ATLGVKLGTVRSRIHRGRQQLRAALAA 188
 
Name Accession Description Interval E-value
PRK09647 PRK09647
RNA polymerase sigma factor SigE; Reviewed
18-202 6.93e-115

RNA polymerase sigma factor SigE; Reviewed


Pssm-ID: 236606 [Multi-domain]  Cd Length: 203  Bit Score: 325.97  E-value: 6.93e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  18 DAASADVTEQLSGTAAFDA--GVGEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGTFEGW 95
Cdd:PRK09647   2 DDDWVEPSDELTGTAVFDAtgDKATMPSWEELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSLQNYQPGTFEGW 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  96 LHRITTNLFLDMVRHRQVIRMEALPENYDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIA 175
Cdd:PRK09647  82 LHRITTNLFLDMVRRRARIRMEALPEDYDRVPGDEPNPEQIYHDARLDPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIA 161
                        170       180
                 ....*....|....*....|....*..
gi 896182377 176 STLGLKMGTVRSRIHRARSSLRATLER 202
Cdd:PRK09647 162 ATLGVKLGTVRSRIHRGRQQLRAALAA 188
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
39-206 1.29e-50

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 162.09  E-value: 1.29e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  39 GEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRP-GTFEGWLHRITTNLFLDMVRHRQViRME 117
Cdd:COG1595   14 GDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGrGSFRAWLYRIARNLAIDHLRKRRR-RRE 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 118 ALPENYDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLR 197
Cdd:COG1595   93 LLDELAEELPDEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVKSRLSRARKKLR 172

                 ....*....
gi 896182377 198 ATLERLEKE 206
Cdd:COG1595  173 EALEEEGAL 181
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
43-200 4.42e-38

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 129.39  E-value: 4.42e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377   43 SWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRP-GTFEGWLHRITTNLFLDMVRHRQVIRMEAlpE 121
Cdd:TIGR02937   2 AFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPeGSFKAWLFRIARNLILDYLRRKRRLRREL--D 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896182377  122 NYDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATL 200
Cdd:TIGR02937  80 LLEELLDSDPSPEEELEQEEEREALREALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKRARKKLRELL 158
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
47-112 7.33e-20

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 79.94  E-value: 7.33e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896182377   47 LVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPG---TFEGWLHRITTNLFLDMVRHRQ 112
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPErgvSFSTWLYTIIRNAIIDYLRKQR 69
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
145-197 8.21e-11

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 55.57  E-value: 8.21e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 896182377 145 DLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLR 197
Cdd:cd06171    3 RLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
 
Name Accession Description Interval E-value
PRK09647 PRK09647
RNA polymerase sigma factor SigE; Reviewed
18-202 6.93e-115

RNA polymerase sigma factor SigE; Reviewed


Pssm-ID: 236606 [Multi-domain]  Cd Length: 203  Bit Score: 325.97  E-value: 6.93e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  18 DAASADVTEQLSGTAAFDA--GVGEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGTFEGW 95
Cdd:PRK09647   2 DDDWVEPSDELTGTAVFDAtgDKATMPSWEELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSLQNYQPGTFEGW 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  96 LHRITTNLFLDMVRHRQVIRMEALPENYDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIA 175
Cdd:PRK09647  82 LHRITTNLFLDMVRRRARIRMEALPEDYDRVPGDEPNPEQIYHDARLDPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIA 161
                        170       180
                 ....*....|....*....|....*..
gi 896182377 176 STLGLKMGTVRSRIHRARSSLRATLER 202
Cdd:PRK09647 162 ATLGVKLGTVRSRIHRGRQQLRAALAA 188
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
39-206 1.29e-50

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 162.09  E-value: 1.29e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  39 GEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRP-GTFEGWLHRITTNLFLDMVRHRQViRME 117
Cdd:COG1595   14 GDEAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGrGSFRAWLYRIARNLAIDHLRKRRR-RRE 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 118 ALPENYDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLR 197
Cdd:COG1595   93 LLDELAEELPDEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVKSRLSRARKKLR 172

                 ....*....
gi 896182377 198 ATLERLEKE 206
Cdd:COG1595  173 EALEEEGAL 181
PRK09652 PRK09652
RNA polymerase sigma factor RpoE; Provisional
46-206 2.08e-46

RNA polymerase sigma factor RpoE; Provisional


Pssm-ID: 236608 [Multi-domain]  Cd Length: 182  Bit Score: 151.50  E-value: 2.08e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  46 ELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGT-FEGWLHRITTNLFLDMVR--HRQVIRMEALPEN 122
Cdd:PRK09652  14 LLVRRYQPRVKRLLSRLTRDPADAEDLVQETFIKAYRALHSFRGGAaFYTWLYRIARNTAINYLRkqGRRPPASDVDAEE 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 123 YD-----RVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLR 197
Cdd:PRK09652  94 AEdfdlaDALRDISTPENELLSAELEQRVRAAIESLPEELRTAITLREIEGLSYEEIAEIMGCPIGTVRSRIFRAREALR 173

                 ....*....
gi 896182377 198 ATLERLEKE 206
Cdd:PRK09652 174 AKLQPLLDE 182
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
43-200 4.42e-38

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 129.39  E-value: 4.42e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377   43 SWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRP-GTFEGWLHRITTNLFLDMVRHRQVIRMEAlpE 121
Cdd:TIGR02937   2 AFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPeGSFKAWLFRIARNLILDYLRRKRRLRREL--D 79
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896182377  122 NYDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATL 200
Cdd:TIGR02937  80 LLEELLDSDPSPEEELEQEEEREALREALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKRARKKLRELL 158
PRK09641 PRK09641
RNA polymerase sigma factor SigW; Provisional
39-203 4.44e-34

RNA polymerase sigma factor SigW; Provisional


Pssm-ID: 182012 [Multi-domain]  Cd Length: 187  Bit Score: 120.19  E-value: 4.44e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  39 GEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPG-TFEGWLHRITTNLFLDMVRHR------ 111
Cdd:PRK09641  15 GDQNAFAELVDLYKDKIYQLCYRMLGNRHEAEDAAQEAFIRAYVNIDSYDINrKFSTWLYRIATNLTIDRLRKRkpdyyl 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 112 --QVIRMEALpENYDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRI 189
Cdd:PRK09641  95 daEVAGTEGL-TMYSQLAADDALPEEQVVSLELQETIQEAILQLPEKYRTVIVLKYIEDLSLKEISEILDLPVGTVKTRI 173
                        170
                 ....*....|....
gi 896182377 190 HRARSSLRATLERL 203
Cdd:PRK09641 174 HRGREALRKQLRHL 187
PRK11924 PRK11924
RNA polymerase sigma factor; Provisional
45-202 5.12e-31

RNA polymerase sigma factor; Provisional


Pssm-ID: 183384 [Multi-domain]  Cd Length: 179  Bit Score: 111.99  E-value: 5.12e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  45 SELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRP-GTFEGWLHRITTNLFLDMVRHRQVIRMEALPENY 123
Cdd:PRK11924  16 SELFRPHAPDLLRYARRQLGDRALAEDAVQEAFLRAWRKADLFNGkGSARTWLLTIARNVCYDLLRRRRREKAVLSDDAL 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 124 DRV-PGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLER 202
Cdd:PRK11924  96 EPEfAETAETPEAALLAKDDLARIDRCLDALPVKQREVFLLRYVEGLSYREIAEILGVPVGTVKSRLRRARQLLRECLEA 175
SigM_subfam TIGR02950
RNA polymerase sigma factor, SigM family; This family of RNA polymerase sigma factors is a ...
49-201 4.65e-28

RNA polymerase sigma factor, SigM family; This family of RNA polymerase sigma factors is a member of the Sigma-70 subfamily (TIGR02937) and is restricted to certain lineages of the order Bacillales. This family encompasses at least two distinct sigma factors as two proteins are found in each of B. anthracis, B. subtilis subsp. subtilis str. 168, and B. lichiniformis (although these are not apparently the same two in each). One of these is designated as SigM in B. subtilis (Swiss_Prot:


Pssm-ID: 274361 [Multi-domain]  Cd Length: 154  Bit Score: 103.69  E-value: 4.65e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377   49 QAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGTFEGWLHRITTNLFLDMVR---HRQVIRMEALPENYDR 125
Cdd:TIGR02950   2 REYMHDVFRYLYRLTKDKHLAEDLLQETFLKAYIHLHSFKDSSIKPWLFRIARNAFIDWYRkdkKIQTIDDDAIGDLEQH 81
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896182377  126 vpgTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLE 201
Cdd:TIGR02950  82 ---PVESPEHHLLIKIEQEEITHHLSRLPENYRTVLILREFKEFSYKEIAELLNLSLAKVKSNLFRARKELKKLLE 154
PRK05602 PRK05602
RNA polymerase sigma factor; Reviewed
37-204 6.83e-28

RNA polymerase sigma factor; Reviewed


Pssm-ID: 235530 [Multi-domain]  Cd Length: 186  Bit Score: 103.96  E-value: 6.83e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  37 GVGEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGT--FEGWLHRITTNLFLDMVRHRQVI 114
Cdd:PRK05602  15 AAGDPAAFRVLVARKLPRLLALATRMLGDPAEAEDVAQETFLRIWKQAPSWRPGEarFDTWLHRVVLNLCYDRLRRRREV 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 115 RMEALPENYDRVPGtlktPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARS 194
Cdd:PRK05602  95 PVEDAPDVPDPAPG----PDAGLEARQRARRVEQALAALPERQREAIVLQYYQGLSNIEAAAVMDISVDALESLLARGRR 170
                        170
                 ....*....|
gi 896182377 195 SLRATLERLE 204
Cdd:PRK05602 171 ALRAQLADLP 180
PRK09638 PRK09638
RNA polymerase sigma factor SigY; Reviewed
39-202 6.83e-28

RNA polymerase sigma factor SigY; Reviewed


Pssm-ID: 182010 [Multi-domain]  Cd Length: 176  Bit Score: 103.95  E-value: 6.83e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  39 GEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRP-GTFEGWLHRITTNLFLDMVRHRQviRME 117
Cdd:PRK09638  15 GDDAALTTLFQQHYSFLYKYLLKLTLDPDLAEDLVQETMLKAIENLSSFQGrSKFSTWLISIASRLYKDHLRKQK--REK 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 118 ALPENYDRVPGTLKTPEQAVDDA----MLDpdleiALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRAR 193
Cdd:PRK09638  93 LRLQRAKEETLRKEKWEAAIKGAewseMLD-----ALSKLDPEFRAPVILKHYYGYTYEEIAKMLNIPEGTVKSRVHHGI 167

                 ....*....
gi 896182377 194 SSLRATLER 202
Cdd:PRK09638 168 KQLRKEWGQ 176
SigE-fam_strep TIGR02983
RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors ...
46-201 1.42e-24

RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.


Pssm-ID: 132028 [Multi-domain]  Cd Length: 162  Bit Score: 94.76  E-value: 1.42e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377   46 ELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYR-PGTFEGWLHRITTNLFLDMVRHRqvIRMEALPENYd 124
Cdd:TIGR02983  10 AFVAARYPRLLRTAYLLTGDPHEAEDLVQEALVRTYVRWDRIRdPDAPDAYVRRVLVNLARSRWRRR--RLLELPTREL- 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  125 rvpgtlktPEQAVDDAMLDPDLEI----ALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATL 200
Cdd:TIGR02983  87 --------PDAAAPDPAPDVALRAalarALRRLPARQRAVVVLRYYEDLSEAQVAEALGISVGTVKSRLSRALARLRELL 158

                  .
gi 896182377  201 E 201
Cdd:TIGR02983 159 E 159
PRK09643 PRK09643
RNA polymerase sigma factor SigM; Reviewed
39-203 3.75e-23

RNA polymerase sigma factor SigM; Reviewed


Pssm-ID: 236604 [Multi-domain]  Cd Length: 192  Bit Score: 92.08  E-value: 3.75e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  39 GEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYR-PGTFEGWLHRITTNLFLDMVRHRQVIRME 117
Cdd:PRK09643  24 GDRYAFGELFRRHHRRLWAVARRTSGTREDAADALQDAMLSAHRAAGSFRgDAAVSSWLHRIVVNACLDRLRRAKARPTV 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 118 ALPENYDrVPGTLKTPEQAVDDAMldpDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLR 197
Cdd:PRK09643 104 PLDDVYP-VAQLERDPTARVETAL---AVQRALMRLPVEQRAALVAVDMQGYSVADAARMLGVAEGTVKSRCARGRARLA 179

                 ....*.
gi 896182377 198 ATLERL 203
Cdd:PRK09643 180 ELLGYL 185
PRK11922 PRK11922
RNA polymerase sigma factor; Provisional
19-202 1.11e-22

RNA polymerase sigma factor; Provisional


Pssm-ID: 237024 [Multi-domain]  Cd Length: 231  Bit Score: 91.56  E-value: 1.11e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  19 AASADVTEQLSGTAAFDAGV------GEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYR-PGT 91
Cdd:PRK11922   1 MTTAPASRPPPLSAASDRELvarvlaGDEAAFEALMRRHNRRLYRTARAILRNDAEAEDVVQEAYLRAFRALGTFRgDAS 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  92 FEGWLHRITTNLFLDMVRHRQVIRMEALPENYDRVPGTLKTPEQAVDDamlDPD-----------LEIALAELQPDYRAV 160
Cdd:PRK11922  81 LSTWLSRIVLNEALGRLRRRRRLVNLAEMVMASTIAGGERTPLADPAE---DPEraaarreiralLERAIDALPDAFRAV 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 896182377 161 VVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLER 202
Cdd:PRK11922 158 FVLRVVEELSVEETAQALGLPEETVKTRLHRARRLLRESLAR 199
PRK09644 PRK09644
RNA polymerase sigma factor SigM; Provisional
46-209 2.00e-22

RNA polymerase sigma factor SigM; Provisional


Pssm-ID: 170033 [Multi-domain]  Cd Length: 165  Bit Score: 89.17  E-value: 2.00e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  46 ELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGTFEGWLHRITTNLFLDMVR-HRQVIRMEAlpenyD 124
Cdd:PRK09644   5 EIYKMYINDVYRYLFSLTKSHHAAEDLLQETFYRAYIYLEDYDNQKVKPWLFKVAYHTFIDFVRkEKKVSFVGT-----D 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 125 RVPGTLKT-PEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLERL 203
Cdd:PRK09644  80 EIEAIQAEsTEEYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEAASVLDLKLNTYKSHLFRGRKRLKALLKEE 159

                 ....*.
gi 896182377 204 EKERQE 209
Cdd:PRK09644 160 KSQNDK 165
PRK12518 PRK12518
RNA polymerase sigma factor; Provisional
39-201 3.91e-22

RNA polymerase sigma factor; Provisional


Pssm-ID: 237124 [Multi-domain]  Cd Length: 175  Bit Score: 88.62  E-value: 3.91e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  39 GEMPSWSELVQAHADSVYGLAYRLTGNQQdAEDLTQETFMRVFRSLKSYR-PGTFEGWLHRITTNLFLDMvRHRQVIRME 117
Cdd:PRK12518   8 GDRQSFRQLYRRYQQKVRSTLYQLCGREL-LDDLVQEVFLRVWKGLPKLRnPAYFSTWLYRITWNVATDA-RRQFAQRPS 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 118 ALPEnyDRVPGTLKTPEQAVDDAMLD-PDL-EIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSS 195
Cdd:PRK12518  86 RIQD--DSLNDQPSRPSDTPDLMQLHyQDLvQQGLQTLSLEHRAVLVLHDLEDLPQKEIAEILNIPVGTVKSRLFYARRQ 163

                 ....*.
gi 896182377 196 LRATLE 201
Cdd:PRK12518 164 LRKFLQ 169
PRK09415 PRK09415
RNA polymerase factor sigma C; Reviewed
45-201 9.22e-22

RNA polymerase factor sigma C; Reviewed


Pssm-ID: 181835 [Multi-domain]  Cd Length: 179  Bit Score: 87.88  E-value: 9.22e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  45 SELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYR-PGTFEGWLHRITTNLFLDMVR---HRQVIRMEalp 120
Cdd:PRK09415  19 DEIMNEYGQEVLQLVYSYVKNKEVAEDLTQEIFVKCYKSLHTYKgKSSLKTWLYRIAINHCKDYLKswhNKKVIVTE--- 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 121 ENYDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATL 200
Cdd:PRK09415  96 DIFTYMESQKESVEEEVIQNAEDERLASAVMSLPIKYREVIYLFYYEELSIKEIAEVTGVNENTVKTRLKKAKELLKKGL 175

                 .
gi 896182377 201 E 201
Cdd:PRK09415 176 E 176
PRK09645 PRK09645
ECF RNA polymerase sigma factor SigL;
51-201 1.25e-21

ECF RNA polymerase sigma factor SigL;


Pssm-ID: 236605 [Multi-domain]  Cd Length: 173  Bit Score: 87.44  E-value: 1.25e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  51 HADSVYGLAYRLTGNQQDAEDLTQETFMRVFR-------SLKSYRPgtfegWLHRITTNLFLDMVRHRQVIRMEALPEny 123
Cdd:PRK09645  18 HAAPLWRYALRLTGDRARAEDVVQETLLRAWQhpevladTGRSARA-----WLFTVARNLVIDERRSARARPVEGGDD-- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 124 drvpgTLKTPEQAVDD----AMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRAT 199
Cdd:PRK09645  91 -----VLGVPEQSAPDevdrALDRLLVADALAQLSPEHRAVLVRSYYRGWSTAQIAADLGIPEGTVKSRLHYALRALRLA 165

                 ..
gi 896182377 200 LE 201
Cdd:PRK09645 166 LQ 167
PRK12540 PRK12540
RNA polymerase sigma factor; Provisional
42-200 7.48e-21

RNA polymerase sigma factor; Provisional


Pssm-ID: 183579 [Multi-domain]  Cd Length: 182  Bit Score: 85.79  E-value: 7.48e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  42 PSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGT-FEGWLHRITTNLFLDMVRHRQvirmEALP 120
Cdd:PRK12540   5 DSLRDDILAAVPSLRAFAISLSGNGDRADDLVQETLLRALANIDSFQPGSnLPAWLFTILRNLFRSDYRKRR----REVE 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 121 ENYDRVPGTLKTpeQAVDDAMLD-PDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRAT 199
Cdd:PRK12540  81 DADGSYAKTLKS--QPGQNAHLEfEEFRAALDKLPQDQREALILVGASGFSYEDAAAICGCAVGTIKSRVNRARSKLSAL 158

                 .
gi 896182377 200 L 200
Cdd:PRK12540 159 L 159
PRK12513 PRK12513
RNA polymerase sigma factor; Provisional
39-200 6.02e-20

RNA polymerase sigma factor; Provisional


Pssm-ID: 183566 [Multi-domain]  Cd Length: 194  Bit Score: 83.59  E-value: 6.02e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  39 GEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRP-GTFEGWLHRITTNLFLDmvRHRQVIRME 117
Cdd:PRK12513  23 GDAAAFEALYARHRTGLYRFLLRLARDRALAEDIFQETWLRVIRARAQYQPrARFRTWLYQIARNLLID--HWRRHGARQ 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 118 ALPENYDR----VPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRAR 193
Cdd:PRK12513 101 APSLDADEqlhaLADDGAAPEQQLSLFRDRRRLQAALETLPDEQREVFLLREHGDLELEEIAELTGVPEETVKSRLRYAL 180

                 ....*..
gi 896182377 194 SSLRATL 200
Cdd:PRK12513 181 QKLRELL 187
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
47-112 7.33e-20

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 79.94  E-value: 7.33e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896182377   47 LVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPG---TFEGWLHRITTNLFLDMVRHRQ 112
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPErgvSFSTWLYTIIRNAIIDYLRKQR 69
PRK12533 PRK12533
RNA polymerase sigma factor; Provisional
46-200 2.55e-19

RNA polymerase sigma factor; Provisional


Pssm-ID: 237129 [Multi-domain]  Cd Length: 216  Bit Score: 82.47  E-value: 2.55e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  46 ELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGTFEGWLHRITTNLFLDMVRHRQVIRMEALPENYD- 124
Cdd:PRK12533  22 QLVLPHLDAAYNLARWLCGNASDADDVVQEACMRALRFFDSFRGDNARPWLLAIVRHTWYSEWRRRANAHEVAAPDTLDd 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 125 --RVPGTLKTPEQAVDDAMLDPDLEI---ALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRAT 199
Cdd:PRK12533 102 adSLDDWQPAGEDPLALLLRAEDVRLvnaALAKLPVEYREVLVLRELEDMSYREIAAIADVPVGTVMSRLARARRRLAAL 181

                 .
gi 896182377 200 L 200
Cdd:PRK12533 182 L 182
PRK08241 PRK08241
RNA polymerase subunit sigma-70;
39-198 4.36e-19

RNA polymerase subunit sigma-70;


Pssm-ID: 236196 [Multi-domain]  Cd Length: 339  Bit Score: 83.83  E-value: 4.36e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  39 GEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRP-GTFEGWLHRITTNLFLDMVRHRQ--VIR 115
Cdd:PRK08241  16 GDRDAFAALVEPHRRELLAHCYRMLGSVHDAEDAVQETLLRAWRGYDRFEGrSSLRTWLYRIATNVCLDALEGRArrPLP 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 116 MEALPENYDRVPGTLKTPEQA---------VDDAMLDPD--------LEIA-LAELQ---PDYRAVVVLCDVVGLTYEEI 174
Cdd:PRK08241  96 TDLGAPAADPVDELVERPEVPwlepypdalLDPAAADPAarvvaresVRLAfVAALQhlpPRQRAVLILRDVLGWSAAEV 175
                        170       180
                 ....*....|....*....|....
gi 896182377 175 ASTLGLKMGTVRSRIHRARSSLRA 198
Cdd:PRK08241 176 AELLDTSVAAVNSALQRARATLAE 199
PRK12517 PRK12517
RNA polymerase sigma factor; Provisional
47-208 2.21e-18

RNA polymerase sigma factor; Provisional


Pssm-ID: 183569 [Multi-domain]  Cd Length: 188  Bit Score: 79.35  E-value: 2.21e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  47 LVQA-HADsVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYR-PGTFEGWLhrITtnlfldMVRHRQVIRMEALPENYD 124
Cdd:PRK12517  28 LVKAlHAD-IYRYAYWLCKDKHIAEDLVQETFLRAWRSLDSLKdEKAAKAWL--IT------ILRRENARRFERKQFDLV 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 125 RVpgtlkTPEQAVDDAMLDPDLEIA-------LAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLR 197
Cdd:PRK12517  99 DI-----EDDSIEDDASHSSEEEMEqewlrrqIAKLDPEYREPLLLQVIGGFSGEEIAEILDLNKNTVMTRLFRARNQLK 173
                        170
                 ....*....|.
gi 896182377 198 ATLERLEKERQ 208
Cdd:PRK12517 174 EALEKPDVQRG 184
PRK09637 PRK09637
RNA polymerase sigma factor SigZ; Provisional
65-208 3.52e-18

RNA polymerase sigma factor SigZ; Provisional


Pssm-ID: 236601 [Multi-domain]  Cd Length: 181  Bit Score: 78.49  E-value: 3.52e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  65 NQQDAEDLTQETFMRVFRSLKSYRPGT-FEGWLHRITTNLFLDMVRHRQviRMEALPEN---YDRVPGtlktpEQAVDDa 140
Cdd:PRK09637  24 NEADVDDLLQEVLIKTHSNLHSLKDGSsIKSWLYQIANNTIIDFYRKKN--RSEELPDDllfEDEERE-----ENAKKE- 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896182377 141 mLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLE---RLEKERQ 208
Cdd:PRK09637  96 -LAPCLRPFIDALPEKYAEALRLTELEGLSQKEIAEKLGLSLSGAKSRVQRGRVKLKELLEgccDFEIDRQ 165
SigX4 TIGR02957
RNA polymerase sigma-70 factor, TIGR02957 family; This group of sigma factors are members of ...
46-212 5.91e-18

RNA polymerase sigma-70 factor, TIGR02957 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building and bidirectional best hits, to represent a conserved family. This family is found in a limited number of bacterial lineages. This family includes apparent paralogous expansion in Streptomyces coelicolor A3(2), and multiple copies in Mycobacterium smegmatis MC2, Streptomyces avermitilis MA-4680 and Nocardia farcinica IFM10152.


Pssm-ID: 132002 [Multi-domain]  Cd Length: 281  Bit Score: 80.09  E-value: 5.91e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377   46 ELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSyRPGTFEGWLHRITTNLFLDMVR----HRQVIRMEALPE 121
Cdd:TIGR02957   1 EEFEALRPLLFSLAYRMLGSVADAEDIVQETFLRWQEADRA-QIENPKAYLTKVVTRRCIDVLRsaraRREVYVGPWLPE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  122 NydrVPGTLKTPEQAVDDAmldPDLEIA----LAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLR 197
Cdd:TIGR02957  80 P---LLTTSADPAESVELA---ESLSMAylllLERLSPLERAVFVLREVFDYPYEEIASIVGKSEANCRQLVSRARRHLD 153
                         170
                  ....*....|....*...
gi 896182377  198 ATLERLE---KERQELPE 212
Cdd:TIGR02957 154 ARRPRFEvsrEESRQLLE 171
algU PRK11923
RNA polymerase sigma factor AlgU; Provisional
47-206 2.15e-17

RNA polymerase sigma factor AlgU; Provisional


Pssm-ID: 171347 [Multi-domain]  Cd Length: 193  Bit Score: 76.76  E-value: 2.15e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  47 LVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYR-PGTFEGWLHRITTNLFLD--MVRHRQVIRMEALPENY 123
Cdd:PRK11923  25 LVLKYQHKILGLIVRFVHDTAEAQDVAQEAFIKAYRALGNFRgDSAFYTWLYRIAINTAKNhlVSRGRRPPDSDVSSEDA 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 124 DRVPGT-----LKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRA 198
Cdd:PRK11923 105 EFYDGDhalkdIESPERALLRDEIEGTVHRTIQQLPEDLRTALTLREFDGLSYEDIASVMQCPVGTVRSRIFRAREAIDK 184

                 ....*...
gi 896182377 199 TLERLEKE 206
Cdd:PRK11923 185 ALQPLLQE 192
PRK12519 PRK12519
RNA polymerase sigma factor; Provisional
51-203 2.57e-17

RNA polymerase sigma factor; Provisional


Pssm-ID: 237125 [Multi-domain]  Cd Length: 194  Bit Score: 76.64  E-value: 2.57e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  51 HADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSlKSYRP--GTFEGWLHRITTNLFLDMVRHRQviRMEALPENYDRVPG 128
Cdd:PRK12519  38 HAGLVYGLALKILGNSQEAEDLTQEIFLSLWRK-SSYDPkrGSLSSYLLTLTRSRAIDRLRSRR--SRQRLLERWQQELL 114
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896182377 129 TLKTPEQAVDDAMLDP---DLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLERL 203
Cdd:PRK12519 115 GEASEDTPLEQASLAErsqRVQTALAQLPESQRQVLELAYYEGLSQSEIAKRLGIPLGTVKARARQGLLKLRELLQDL 192
PRK12541 PRK12541
RNA polymerase sigma factor; Provisional
43-201 9.61e-17

RNA polymerase sigma factor; Provisional


Pssm-ID: 183580 [Multi-domain]  Cd Length: 161  Bit Score: 74.20  E-value: 9.61e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  43 SWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGTFEGWLHRITTNLFLDMVRHRQVIRMEALPEN 122
Cdd:PRK12541   6 SLEEIYSEHMQDLFRYLLSLTGDSHFAEDLMQETFYRMLVHIDYYKGEEIRPWLFTIAYNAFIDWYRKEKKYKTTTIEEF 85
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896182377 123 YdrVPGTLKTPEQAVDDAMLDPDLEiALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLE 201
Cdd:PRK12541  86 H--LPNVPSTEHEYFIKHEIASWLD-SLSSLPLERRNVLLLRDYYGFSYKEIAEMTGLSLAKVKIELHRGRKETKSIKE 161
PRK12534 PRK12534
RNA polymerase sigma factor; Provisional
28-202 5.99e-16

RNA polymerase sigma factor; Provisional


Pssm-ID: 183576 [Multi-domain]  Cd Length: 187  Bit Score: 72.78  E-value: 5.99e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  28 LSGTAAfdagvGEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGTFEG--WLHRITTNLFL 105
Cdd:PRK12534  16 LTATAG-----GDRHAFEALYRQTSPKLFGVCLRMIPQRAEAEEVLQDVFTLIWHKAGQFDPSRARGltWLAMIARNKAI 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 106 DMVRHRQVIRMEALPENYDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTV 185
Cdd:PRK12534  91 DHLRANAPQRRNVALDDAGELRAADASPLERTERASTRRRIDHCLAELEPPRSELIRTAFFEGITYEELAARTDTPIGTV 170
                        170
                 ....*....|....*..
gi 896182377 186 RSRIHRARSSLRATLER 202
Cdd:PRK12534 171 KSWIRRGLAKLKACLER 187
PRK09639 PRK09639
RNA polymerase sigma factor SigX; Provisional
42-206 6.36e-16

RNA polymerase sigma factor SigX; Provisional


Pssm-ID: 236602 [Multi-domain]  Cd Length: 166  Bit Score: 72.29  E-value: 6.36e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  42 PSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRpGTFEGWLHRITTNLFLDMVRHRQVIRMEALpe 121
Cdd:PRK09639   3 ETFEDLFEQYYPDVVQQIFYIVKDRTQAEDLAQEVFLRLYRSDFKGI-ENEKGWLIKSARNVAYNYLRSEKRRRARIL-- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 122 nydrvpgtlKTPEQAVDDAMLDPDlEIA------------LAELQPDYRAVVVLcDVVGLTYEEIASTLGLKMGTVRSRI 189
Cdd:PRK09639  80 ---------GEFQWQEVDNEPSPE-EIWirkeeitkvqevLAKMTERDRTVLLL-RFSGYSYKEIAEALGIKESSVGTTL 148
                        170
                 ....*....|....*..
gi 896182377 190 HRARSSLRATLERLEKE 206
Cdd:PRK09639 149 ARAKKKFRKIYEQMEEE 165
PRK12538 PRK12538
RNA polymerase sigma factor; Provisional
1-206 1.01e-15

RNA polymerase sigma factor; Provisional


Pssm-ID: 139048 [Multi-domain]  Cd Length: 233  Bit Score: 72.97  E-value: 1.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377   1 MPERVKSERVSAGASREDAASADVTEQLSGTAAFDAGVGEMpswseLVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRV 80
Cdd:PRK12538  27 APDAASVSIVPDPPPVADAVFDEDEELLDRLATDDEAAFRL-----LVERHIDRAYAIALRIVGNRADAEDVVQDTMLKV 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  81 FRSLKSYRPG--TFEGWLHRITTNLFLDMVRHRQVIRMEALPENYDRVPGTLKTPEQAVDDAMldpdLEIALAELQPDYR 158
Cdd:PRK12538 102 WTHRGRWQHGraKFSTWLYRVVSNRCIDLRRKPRTENVDAVPEVADGKPDAVSVIERNELSDL----LEAAMQRLPEQQR 177
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 896182377 159 AVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLERLEKE 206
Cdd:PRK12538 178 IAVILSYHENMSNGEIAEVMDTTVAAVESLLKRGRQQLRDLLRRHERD 225
PRK12516 PRK12516
RNA polymerase sigma factor; Provisional
38-201 1.03e-15

RNA polymerase sigma factor; Provisional


Pssm-ID: 183568 [Multi-domain]  Cd Length: 187  Bit Score: 72.31  E-value: 1.03e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  38 VGEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGT-FEGWLHRITTNLFLDMVRH--RQVI 114
Cdd:PRK12516   6 VEGTPPFKRELLAALPSLRAFAVSLIGRHDRADDLVQDTIMKAWAKQDHFEVGTnMKAWLFTILRNEFYSQMRKrgREVQ 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 115 RMEAL--------PENYdrvpGTLKTPeqavddamldpDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVR 186
Cdd:PRK12516  86 DTDGMfteqlavhPSQY----GTLDLQ-----------DFRAALDQLPDDQREAIILVGASGFAYEEAAEICGCAVGTIK 150
                        170
                 ....*....|....*
gi 896182377 187 SRIHRARSSLRATLE 201
Cdd:PRK12516 151 SRVNRARQRLQEILQ 165
PRK12511 PRK12511
RNA polymerase sigma factor; Provisional
59-198 1.04e-15

RNA polymerase sigma factor; Provisional


Pssm-ID: 237123 [Multi-domain]  Cd Length: 182  Bit Score: 72.13  E-value: 1.04e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  59 AYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGT-FEGWLHRITTNLFLDMVRHRQVIRMEALPENYDRVPGTLKTPEQAV 137
Cdd:PRK12511  21 ARSLTRDSAEAEDLVHDALVRALERRASFRSGGnLRTWLMSILHNAFIDELRRRRVEARRADELAVLADASLPAAQEHAV 100
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896182377 138 DDAmldpDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRA 198
Cdd:PRK12511 101 RLA----QIRDAFFDLPEEQRAALHLVAIEGLSYQEAAAVLGIPIGTLMSRIGRARAALRA 157
PRK12546 PRK12546
RNA polymerase sigma factor; Provisional
46-217 1.07e-15

RNA polymerase sigma factor; Provisional


Pssm-ID: 139055 [Multi-domain]  Cd Length: 188  Bit Score: 72.18  E-value: 1.07e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  46 ELVQaHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGT-FEGWLHRITTNLFLDMVRH--RQVirmealpEN 122
Cdd:PRK12546  12 ELVE-HLPALRAFAISLTRNVAVADDLVQDTIVKAWTNFDKFQEGTnLRAWLFTILRNTFYSDRRKhkREV-------PD 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 123 YDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLER 202
Cdd:PRK12546  84 PEGVHAASLAVKPAHDGRLAMSDFRAAFAQLPDEQREALILVGASGFSYEEAAEMCGVAVGTVKSRANRARARLAELLQL 163
                        170
                 ....*....|....*
gi 896182377 203 LEKERQELPESVTAG 217
Cdd:PRK12546 164 EEGEELEMTDGATLA 178
sigI PRK09635
RNA polymerase sigma factor SigI; Provisional
45-199 1.92e-15

RNA polymerase sigma factor SigI; Provisional


Pssm-ID: 182008 [Multi-domain]  Cd Length: 290  Bit Score: 73.08  E-value: 1.92e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  45 SELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSyRPGTFEGWLHRITTNLFLDMVRHRQVIRME----ALP 120
Cdd:PRK09635   8 SAAWRAHRAYLVDLAFRMVGDIGVAEDMVQEAFSRLLRAPVG-DIDDERGWLIVVTSRLCLDHIKSASTRRERpqdiAAW 86
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896182377 121 ENYDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRAT 199
Cdd:PRK09635  87 HDGDASVSSVDPADRVTLDDEVRLALLIMLERLGPAERVVFVLHEIFGLPYQQIATTIGSQASTCRQLAHRARRKINES 165
PRK09636 PRK09636
RNA polymerase sigma factor SigJ; Provisional
56-209 2.46e-15

RNA polymerase sigma factor SigJ; Provisional


Pssm-ID: 236600 [Multi-domain]  Cd Length: 293  Bit Score: 73.03  E-value: 2.46e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  56 YGLAYRLTGNQQDAEDLTQETFMRvFRSLKSYRPGTFEGWLHRITTNLFLDMVR----HRQVIRMEALPENydrVPGTLK 131
Cdd:PRK09636  18 LSVAYRMLGSVADAEDIVQEAWLR-WNNADRAQIRDPRAWLTRVVTRLCLDRLRsarhRRETYVGPWLPEP---VVEELD 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 132 TPEQAV---DDAMLDpdLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRAT--LERLEKE 206
Cdd:PRK09636  94 DPLEAVvaaEDLSLA--LMLALERLSPLERAAFLLHDVFGVPFDEIASTLGRSPAACRQLASRARKHVRAArpRFPVSDE 171

                 ...
gi 896182377 207 RQE 209
Cdd:PRK09636 172 EGA 174
PRK12524 PRK12524
RNA polymerase sigma factor; Provisional
46-201 3.52e-15

RNA polymerase sigma factor; Provisional


Pssm-ID: 183573 [Multi-domain]  Cd Length: 196  Bit Score: 71.07  E-value: 3.52e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  46 ELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGT--FEGWLHRITTNLFLDMVRH--RQVIRMEALPE 121
Cdd:PRK12524  30 ALTLRLAPRALAVATRVLGDRAEAEDVTQEAMLRLWRIAPDWRQGEarVSTWLYRVVCNLCTDRLRRrrRASVDLDDAPE 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 122 NYDRVPGTLktpEQAVDDAMLDPdLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLE 201
Cdd:PRK12524 110 PADAAPGAE---EALIEGDRMRA-LDAALAALPERQRQAVVLRHIEGLSNPEIAEVMEIGVEAVESLTARGKRALAALLA 185
PRK12522 PRK12522
RNA polymerase sigma factor; Provisional
46-201 3.98e-15

RNA polymerase sigma factor; Provisional


Pssm-ID: 183571 [Multi-domain]  Cd Length: 173  Bit Score: 70.28  E-value: 3.98e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  46 ELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYR-PGTFEGWLHRITTNLFLDMVRHRQ----VIRMEALP 120
Cdd:PRK12522   7 ELIDIYKQQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSyVENYKKWITTICVRTFYDFYRKKKrwkdRILDLFHK 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 121 ENYDRV--PGTLKTPE---QAVDDAMLdpdlEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSS 195
Cdd:PRK12522  87 EDGGEIefADDVNISEefiQKVEAEMI----REVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAKKQ 162

                 ....*.
gi 896182377 196 LRATLE 201
Cdd:PRK12522 163 MREHLE 168
PRK12543 PRK12543
RNA polymerase sigma factor; Provisional
39-210 4.39e-15

RNA polymerase sigma factor; Provisional


Pssm-ID: 183582 [Multi-domain]  Cd Length: 179  Bit Score: 70.15  E-value: 4.39e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  39 GEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSY---RPgtFEGWLHRITTNLFLDMVRHR---- 111
Cdd:PRK12543   4 GDQEAFSEIYDVTIQEVYKTVHFLVEDKQDVDDVVNEIYIQLWESLRKYdsnRP--FRFWLIGLVIKQIHSWRRKRwrrf 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 112 ---QVIRMEALPENYDrvpgtlkTPEQAVDDAMlDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSR 188
Cdd:PRK12543  82 rifEKAEEQRKPVSID-------FSEDVLSKES-NQELIELIHKLPYKLRQVIILRYLHDYSQEEIAQLLQIPIGTVKSR 153
                        170       180
                 ....*....|....*....|..
gi 896182377 189 IHRARSSLRATLERLEKERQEL 210
Cdd:PRK12543 154 IHAALKKLRQKEQIEEIFLGEV 175
PRK12535 PRK12535
RNA polymerase sigma factor; Provisional
33-196 1.32e-14

RNA polymerase sigma factor; Provisional


Pssm-ID: 237130 [Multi-domain]  Cd Length: 196  Bit Score: 69.54  E-value: 1.32e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  33 AFDAGVGEMPSWSELVQAHADSVYGLAYRLTGNQQdAEDLTQETFMRVFRSLKSYRP-GTFEGWLHRITTNLFLDMVRHr 111
Cdd:PRK12535  16 ALAAGRGDRAALTEFIRETQDDVWRLLAHLGGHDI-ADDLTQETYLRVMSALPRFAArSSARTWLLSLARRVWVDNIRH- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 112 QVIRMEALPENYDRVPGTLKTPEQAVDDAMLdPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHR 191
Cdd:PRK12535  94 DMARPRKSATEYEDAAATTASNETTGSWSEW-IDVRTLIDALPPERREALILTQVLGYTYEEAAKIADVRVGTIRSRVAR 172

                 ....*
gi 896182377 192 ARSSL 196
Cdd:PRK12535 173 ARADL 177
PRK12547 PRK12547
RNA polymerase sigma factor; Provisional
54-200 1.75e-14

RNA polymerase sigma factor; Provisional


Pssm-ID: 139056 [Multi-domain]  Cd Length: 164  Bit Score: 68.36  E-value: 1.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  54 SVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGT-FEGWLHRITTNLFLDMVRH--RQVIRMEALPENYDRVPgtl 130
Cdd:PRK12547  18 ALRAFAVSLSSKHDKAEDLVQDTLMKAWAKQDSFEMGTnLKAWLFTILRNEFYSQMRKrgREVQDSDGVFTARVAVH--- 94
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896182377 131 ktPEQavdDAMLD-PDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATL 200
Cdd:PRK12547  95 --PAQ---YGSLDlQDFKKALNLLSADQREAIILIGASGFSYEDAAAICGCAVGTIKSRVSRARNRLQELL 160
PRK12542 PRK12542
RNA polymerase sigma factor; Provisional
46-214 5.34e-14

RNA polymerase sigma factor; Provisional


Pssm-ID: 183581 [Multi-domain]  Cd Length: 185  Bit Score: 67.38  E-value: 5.34e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  46 ELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLK---SYRPGTFEGWLHRITTNLFLDMVRHRQviRMEALPEN 122
Cdd:PRK12542  13 ELYELYEQKVYYVAYSILNNIQQAEDAVQETFITLYKNLEklhSLNTQELKRYILRVAKNKAIDSYRKNK--RHETFLEE 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 123 YDR--VPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATL 200
Cdd:PRK12542  91 YEResIEAVDENIEEWEKRKMSEVQIDTLLKELNESNRQVFKYKVFYNLTYQEISSVMGITEANVRKQFERARKRVQNMI 170
                        170
                 ....*....|....*
gi 896182377 201 ERLEK-ERQELPESV 214
Cdd:PRK12542 171 GGIQHdEFKELQRNI 185
PRK13919 PRK13919
putative RNA polymerase sigma E protein; Provisional
39-200 2.16e-13

putative RNA polymerase sigma E protein; Provisional


Pssm-ID: 184395 [Multi-domain]  Cd Length: 186  Bit Score: 65.71  E-value: 2.16e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  39 GEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRP--GTFEGWLHRITTNLFLDMVRHRQViRM 116
Cdd:PRK13919  20 GEEEALRALFRRYAGAFLALARRMGLDGAAAEDVVQEVFIRVWKKAKEFDPrrGSARAWLLALAHHAAVDHVRRRAA-RP 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 117 EAL------PENYDrVPGTLKTPEQAVDDAMLdpdlEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIH 190
Cdd:PRK13919  99 QPLepderePEAFD-LPGPGLDEEGHLDRTRL----GRALKALSPEERRVIEVLYYQGYTHREAAQLLGLPLGTLKTRAR 173
                        170
                 ....*....|
gi 896182377 191 RARSSLRATL 200
Cdd:PRK13919 174 RALSRLKEVL 183
PRK09640 PRK09640
RNA polymerase sigma factor SigX; Reviewed
44-213 2.58e-13

RNA polymerase sigma factor SigX; Reviewed


Pssm-ID: 236603 [Multi-domain]  Cd Length: 188  Bit Score: 65.73  E-value: 2.58e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  44 WSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYR-PGTFEGWLHRITTNLFLDMVRHRQVIRMEALPEN 122
Cdd:PRK09640  28 YEELMRRYQRTLFNVCARYLGNDRDADDVCQEVMLKVLYGLKNFEgKSKFKTWLYSITYNECITQYRKERRKRRLMDALS 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 123 YDRVpgtlktpEQAVDDAMLDPDLEIAL----AELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRArsslra 198
Cdd:PRK09640 108 LDPL-------EEASEEKAPKPEERGGLdrwlVHVNPIDREILVLRFVAELEFQEIADIMHMGLSATKMRYKRA------ 174
                        170
                 ....*....|....*
gi 896182377 199 tLERLEKERQELPES 213
Cdd:PRK09640 175 -LDKLREKFAGLAET 188
PRK12514 PRK12514
RNA polymerase sigma factor; Provisional
37-202 4.33e-13

RNA polymerase sigma factor; Provisional


Pssm-ID: 105710 [Multi-domain]  Cd Length: 179  Bit Score: 64.84  E-value: 4.33e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  37 GVGEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGTFE--GWLHRITTNLFLDMVRHRQVI 114
Cdd:PRK12514  14 SLGDRDAFSSLYDATSAKLFGICLRVLKDRSEAEEALQDVYVKIWTKADRFAVSGLSpmTWLITIARNHAIDRLRARKAV 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 115 RMEaLPENYDRVPGTlKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARS 194
Cdd:PRK12514  94 AVD-IDEAHDLADPS-PGPEAEVIAGDEGQRIDACLEELEKDRAAAVRRAYLEGLSYKELAERHDVPLNTMRTWLRRSLL 171

                 ....*...
gi 896182377 195 SLRATLER 202
Cdd:PRK12514 172 KLRECLSR 179
PRK12515 PRK12515
RNA polymerase sigma factor; Provisional
51-207 6.72e-13

RNA polymerase sigma factor; Provisional


Pssm-ID: 183567 [Multi-domain]  Cd Length: 189  Bit Score: 64.37  E-value: 6.72e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  51 HADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSlksyrPGTFEG------WLHRITTNLFLDMVRHRQVIRMEalPENYD 124
Cdd:PRK12515  31 HHVRVYRFGLRLVRDEQTAEDLVSEVFLDVWRQ-----AGQFEGrsqvstWLLSIARFKALSALRRRKHEEID--DEAAA 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 125 RVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLERLE 204
Cdd:PRK12515 104 AIEDGADTPEVALQKSDTSAALRACLAKLSPAHREIIDLVYYHEKSVEEVGEIVGIPESTVKTRMFYARKKLAELLKAAG 183

                 ...
gi 896182377 205 KER 207
Cdd:PRK12515 184 VER 186
Sigma70_r4_2 pfam08281
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
149-196 8.33e-13

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.


Pssm-ID: 400535 [Multi-domain]  Cd Length: 54  Bit Score: 60.93  E-value: 8.33e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 896182377  149 ALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSL 196
Cdd:pfam08281   7 ALEELPPRQREVFLLRYLEGLSYAEIAELLGISEGTVKSRLSRARKKL 54
PRK09649 PRK09649
RNA polymerase sigma factor SigC; Reviewed
33-202 6.65e-12

RNA polymerase sigma factor SigC; Reviewed


Pssm-ID: 137458 [Multi-domain]  Cd Length: 185  Bit Score: 61.98  E-value: 6.65e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  33 AFDAGVGEMPSWSELVQAHADSVYGLAYRLTgNQQDAEDLTQETFMRVFRSLKSYRP-GTFEGWLHRITTNLFLDMVRHR 111
Cdd:PRK09649  15 ALSAAKGNGRALEAFIKATQQDVWRFVAYLS-DVGSADDLTQETFLRAIGAIPRFSArSSARTWLLAIARHVVADHIRHV 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 112 QViRMEALPENYDRVPGTLKTPEQAVDDAMldpDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHR 191
Cdd:PRK09649  94 RS-RPRTTRGARPEHLIDGDRHARGFEDLV---EVTTMIADLTTDQREALLLTQLLGLSYADAAAVCGCPVGTIRSRVAR 169
                        170
                 ....*....|.
gi 896182377 192 ARSSLRATLER 202
Cdd:PRK09649 170 ARDALLADAEP 180
PRK12537 PRK12537
RNA polymerase sigma factor; Provisional
39-201 1.54e-11

RNA polymerase sigma factor; Provisional


Pssm-ID: 171568 [Multi-domain]  Cd Length: 182  Bit Score: 60.56  E-value: 1.54e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  39 GEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRP--GTFEGWLHRITTNLFLDMVRHRQvirm 116
Cdd:PRK12537  20 GDRRALQALYQQESARLLGVARRIVRDRALAEDIVHDAFIKIWTGAASFDParGSARGWIYSVTRHLALNVLRDTR---- 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 117 EALPENYDRVPgTLKTPEQAVD--DAMLDP-DLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRAR 193
Cdd:PRK12537  96 REVVLDDDAEE-TAQTLHEIIDdfDLWANSgKIHRCLEQLEPARRNCILHAYVDGCSHAEIAQRLGAPLGTVKAWIKRSL 174

                 ....*...
gi 896182377 194 SSLRATLE 201
Cdd:PRK12537 175 KALRECMG 182
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
145-197 8.21e-11

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 55.57  E-value: 8.21e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 896182377 145 DLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLR 197
Cdd:cd06171    3 RLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
Sig-70_gvs1 TIGR02989
RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma ...
47-198 1.84e-10

RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are abundantly found in the species Rhodopirellula baltica (11), and Verrucomicrobium spinosum (16) and to a lesser extent in Gemmata obscuriglobus (2).


Pssm-ID: 274379 [Multi-domain]  Cd Length: 159  Bit Score: 57.33  E-value: 1.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377   47 LVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGT-FEGWLHRITTNLFL----DMVRHRQVIRMEAL-- 119
Cdd:TIGR02989   6 LLTRHERALRAFVRSLVADRDDVDDVLQETFVVAWRKFDQFDPGTnFVAWARGIARNKVLnyrrKLGRDRLVFDDDLLea 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  120 --PENYDRVPGTLKTPEQAvddamldpdLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLR 197
Cdd:TIGR02989  86 laAEAEPTEAERLSDDRQA---------LEGCLEKLPERQRELLDLRYQRGQKATALAEQTGRTVNAVYKALQRIRVSLR 156

                  .
gi 896182377  198 A 198
Cdd:TIGR02989 157 E 157
PRK09646 PRK09646
ECF RNA polymerase sigma factor SigK;
11-200 1.85e-09

ECF RNA polymerase sigma factor SigK;


Pssm-ID: 182015 [Multi-domain]  Cd Length: 194  Bit Score: 55.06  E-value: 1.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  11 SAGASREDAASADVTEQLSGTAAfdagvGEMPSWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRP- 89
Cdd:PRK09646   4 AVPMTGPPAESPDLDALLRRVAR-----GDQDAFAELYDRTSSRVYGLVRRVLRDPGYSEETTQEVYLEVWRTASRFDPa 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  90 -GTFEGWLhrittnlfLDMVRHRQVIRM---EALPENYDRVPGTLKTPE--QAVDDAMLDPDLEI---ALAELQPDYRAV 160
Cdd:PRK09646  79 rGSALAWL--------LTLAHRRAVDRVrseQAASQREVRYGARNVDPAfdQVAEEVEARLERERvrdCLDALTDTQRES 150
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 896182377 161 VVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATL 200
Cdd:PRK09646 151 VTLAYYGGLTYREVAERLAVPLGTVKTRMRDGLIRLRDCL 190
PRK09642 PRK09642
RNA polymerase sigma factor;
48-197 4.78e-09

RNA polymerase sigma factor;


Pssm-ID: 170031 [Multi-domain]  Cd Length: 160  Bit Score: 53.57  E-value: 4.78e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  48 VQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGTFEGWLHRITTNLFLDMVRH--RQVIRMEALPENYDR 125
Cdd:PRK09642   1 MQTYRHYIFQVIFSILRHEEDAKDVTQEVFVKIHASLPNYQFRGLKTWMARIATNHAIDYKRKkaRENEELSLCKETEEN 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896182377 126 VPGTlktpeQAVDDAMLDPDLEIALA----ELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLR 197
Cdd:PRK09642  81 IKSS-----HNIEDLLLTKEQKLLIAqklrELPENYRDVVLAHYLEEKSYQEIALQEKIEVKTVEMKLYRARKWIK 151
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
149-198 5.30e-09

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 50.50  E-value: 5.30e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 896182377  149 ALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRA 198
Cdd:pfam04545   1 ALASLPPRERQVLVLRYGEGLTLEEIGERLGISRERVRQIEKRALRKLRK 50
PRK12532 PRK12532
RNA polymerase sigma factor; Provisional
69-202 6.31e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 171564 [Multi-domain]  Cd Length: 195  Bit Score: 53.78  E-value: 6.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  69 AEDLTQETFMRVFRSLKSYR-PGTFEGWLHRITTNLFLDMVRHR-------QVIRMEALPENYDRV------------PG 128
Cdd:PRK12532  33 AEDLVQETLLSAYSAGDSFQgRALVNSWLFAILKNKIIDALRQIgrqrkvfTLLDDELLDEAFESHfsqnghwtpegqPQ 112
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896182377 129 TLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLER 202
Cdd:PRK12532 113 HWNTPEKSLNNNEFQKILQSCLYNLPENTARVFTLKEILGFSSDEIQQMCGISTSNYHTIMHRARESLRQCLQI 186
PRK12527 PRK12527
RNA polymerase sigma factor; Reviewed
58-198 1.18e-08

RNA polymerase sigma factor; Reviewed


Pssm-ID: 171560 [Multi-domain]  Cd Length: 159  Bit Score: 52.47  E-value: 1.18e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  58 LAYRLtGNQQDAEDLTQETFMRVFRSLKSYRPGTFEGWLHRITTNLFLDMVRHRQVIRMEALPENYDRVPGTLKTPEQAV 137
Cdd:PRK12527  12 LSARL-GNRQAAEDVAHDAYLRVLERSSSAQIEHPRAFLYRTALNLVVDRHRRHRVRQAEPLEVLDEEERLHSPSPQTRL 90
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896182377 138 DDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRA----RSSLRA 198
Cdd:PRK12527  91 DLGQRLALLQRALAELPPACRDSFLLRKLEGLSHQQIAEHLGISRSLVEKHIVNAmkhcRVRMRQ 155
PRK09648 PRK09648
RNA polymerase sigma factor ShbA;
61-202 4.39e-08

RNA polymerase sigma factor ShbA;


Pssm-ID: 236607 [Multi-domain]  Cd Length: 189  Bit Score: 51.12  E-value: 4.39e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  61 RLTGNQQDAEDLTQETFMRVFRSLKSY----RPgtFEGWLHRITTNLFLD----MVRHRQViRMEALPENYDRVPGtlkt 132
Cdd:PRK09648  47 GVERPGLSADDVAQEVCLAVITALPRYrdqgRP--FLAFVYGIAAHKVADahraAGRDKAV-PTEEVPERPSDDAG---- 119
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 133 PEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLER 202
Cdd:PRK09648 120 PEERALRSESSNRMRELLDTLPEKQREILILRVVVGLSAEETAEAVGSTPGAVRVAQHRALARLRAEIEA 189
PRK12536 PRK12536
RNA polymerase sigma factor; Provisional
61-200 2.66e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 237131 [Multi-domain]  Cd Length: 181  Bit Score: 48.89  E-value: 2.66e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  61 RLTGNQQDAEDLTQETFMRVFRSLKSYRPGT-FEGWLHRITTNLFLDMVRHRQviRMEALPENYDRVPGTLKTPEQAVDD 139
Cdd:PRK12536  41 RLPQLPDEVEDLVQEILLAVHNARHTYRADQpLTAWVHAIARYKLMDFLRSRA--RREALHDPLDDESELFATSDDEAAE 118
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896182377 140 AMLDpdLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATL 200
Cdd:PRK12536 119 ARRD--LGKLLEQLPDRQRLPIVHVKLEGLSVAETAQLTGLSESAVKVGIHRGLKALAAKI 177
PRK12512 PRK12512
RNA polymerase sigma factor; Provisional
68-200 7.95e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 171551 [Multi-domain]  Cd Length: 184  Bit Score: 47.77  E-value: 7.95e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  68 DAEDLTQETFMRVFRSLKSYRPGT-FEGWLHRITTNLFLDMVRHRQViRMEAlpeNYDRVPGTLKTPEQAvdDAMLDPDL 146
Cdd:PRK12512  52 QAEDIVQEILLAVHLKRHTWDPGApFAPWLFAIARNKLIDALRRRGR-RVFV---DIDDFAETLPAEPAT--ETLPAGDV 125
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 896182377 147 EIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATL 200
Cdd:PRK12512 126 GRHLETLPPRQRDVVQSISVEGASIKETAAKLSMSEGAVRVALHRGLAALAAKF 179
PRK12544 PRK12544
RNA polymerase factor sigma-70;
64-201 1.05e-06

RNA polymerase factor sigma-70;


Pssm-ID: 183583 [Multi-domain]  Cd Length: 206  Bit Score: 47.49  E-value: 1.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  64 GNQQDAEDLTQETFMRVFRSLKSY-RPGTFEGWLHRITTNLFLDMVRHR-------QVIRMEALPENYDRV--------- 126
Cdd:PRK12544  40 SDLHLAEDAVQEALIGALKNADSFaGRAAFKTWVFAILKNKIIDLLRQKkrhvsasSLLRDEEEEEDFEELfdesghwqk 119
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896182377 127 ---PGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLE 201
Cdd:PRK12544 120 derPQAWGNPEESLEQEQFWRIFEACLDGLPAKYARVFMMREFIELETNEICHAVDLSVSNLNVLLYRARLRLRECLE 197
PRK06930 PRK06930
positive control sigma-like factor; Validated
116-193 2.99e-06

positive control sigma-like factor; Validated


Pssm-ID: 180757 [Multi-domain]  Cd Length: 170  Bit Score: 45.88  E-value: 2.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 116 MEALPENYDRVPGTLKTPEQAV---DDAMLdpdlEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRA 192
Cdd:PRK06930  79 IQRYFRSMEDLEWDIEEPESVIsewDKIRI----EDALSVLTEREKEVYLMHRGYGLSYSEIADYLNIKKSTVQSMIERA 154

                 .
gi 896182377 193 R 193
Cdd:PRK06930 155 E 155
PRK12531 PRK12531
RNA polymerase sigma factor; Provisional
58-201 3.63e-06

RNA polymerase sigma factor; Provisional


Pssm-ID: 105726 [Multi-domain]  Cd Length: 194  Bit Score: 45.69  E-value: 3.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  58 LAYRLTGNQQDAEDLTQETFMRVFR--SLKSYRPGTFEGWLHRITTNLFLDMVRHRQ-----VIRMEALPENYdrVPGTL 130
Cdd:PRK12531  43 FAMKHVGNEQVAMEMVQETMSTVWQkaHLFDGQKSALSTWIYTIIRNLCFDLLRKQKgkdlhIHADDIWPSDY--YPPDL 120
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896182377 131 ---KTPEQAVDDAMLDPDLEIaLAELQPDYRAVVVLCDvvgLTYEEIASTLGLKMGTVRSRIHRARSSLRATLE 201
Cdd:PRK12531 121 vdhYSPEQDMLKEQVMKFLDR-LPKAQRDVLQAVYLEE---LPHQQVAEMFDIPLGTVKSRLRLAVEKLRHSMD 190
PRK06704 PRK06704
RNA polymerase subunit sigma-70;
62-201 7.69e-06

RNA polymerase subunit sigma-70;


Pssm-ID: 180663 [Multi-domain]  Cd Length: 228  Bit Score: 45.40  E-value: 7.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  62 LTGNQQDAEDLTQETFMRVfrsLKSYRPGTF-EGWLHRITTNLFLDMVRHRQVirMEALPENYdrvpgTLKTPEQAVDDa 140
Cdd:PRK06704  37 LTKNKWDGEDLAQETVCKV---LQKYSNKDIcMTLVYKIARNRWLDQIKSKSV--HEKIRDQI-----TFEEPHEKIAD- 105
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896182377 141 mLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLE 201
Cdd:PRK06704 106 -LHEMVGKVLSSLNVQQSAILLLKDVFQYSIADIAKVCSVSEGAVKASLFRSRNRLKTVSE 165
PRK12528 PRK12528
RNA polymerase sigma factor; Provisional
47-192 1.68e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 171561 [Multi-domain]  Cd Length: 161  Bit Score: 43.68  E-value: 1.68e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  47 LVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFRSLKSYRPGTFEGWLHRITTNLFLDMVRHRQVIR--MEALPENYD 124
Cdd:PRK12528   9 LYSAHHHWLTGWLRRRLGCPQSAADLAQDTFVKVLVARETAQIIEPRAFLTTIAKRVLCNHYRRQDLERayLEALAQLPE 88
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 125 RVpgtlkTPEQAVDDAMLDPDLEI--ALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRA 192
Cdd:PRK12528  89 RV-----APSEEERAIILETLVELdqLLDGLPPLVKRAFLLAQVDGLGYGEIATELGISLATVKRYLNKA 153
PRK09651 PRK09651
RNA polymerase sigma factor FecI; Provisional
43-206 2.74e-05

RNA polymerase sigma factor FecI; Provisional


Pssm-ID: 182018 [Multi-domain]  Cd Length: 172  Bit Score: 42.87  E-value: 2.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  43 SWSELVQAHADSVYGLAYRLTGNQQDAEDLTQETFMRVFR--SLKSYR-PGTFegwLHRITTNLFLDMVRHRQVIR---- 115
Cdd:PRK09651  11 TFESLYGTHHGWLKSWLTRKLQSAFDADDIAQDTFLRVMVseTLSTIRdPRSF---LCTIAKRVMVDLFRRNALEKayle 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 116 -MEALPENYDRVP----GTLKTPEQAvdDAMLDpdleialaELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIh 190
Cdd:PRK09651  88 mLALMPEGGAPSPeereSQLETLQLL--DSMLD--------GLNGKTREAFLLSQLDGLTYSEIAHKLGVSVSSVKKYV- 156
                        170
                 ....*....|....*.
gi 896182377 191 rARSSLRATLERLEKE 206
Cdd:PRK09651 157 -AKATEHCLLFRLEYG 171
PRK12529 PRK12529
RNA polymerase sigma factor; Provisional
58-192 3.40e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 183574 [Multi-domain]  Cd Length: 178  Bit Score: 43.00  E-value: 3.40e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  58 LAYRL-TGNQQDAEDLTQETFMRVFRSLKSYRPGTFE---GWLHRITTNLFLDMVRhRQVIRMEALpENYDRVPGTLK-T 132
Cdd:PRK12529  30 LAYRLrSWGRGVADDLAHDIFLRILASRDGGQREAIRqprAYLARIANCVLVSWRR-RQSLELAWL-EALATLPEPLHpS 107
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 133 PEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRA 192
Cdd:PRK12529 108 PEQQSVILETLHEIDALLDTLRPRVKQAFLMATLDGMKQKDIAQALDIALPTVKKYIHQA 167
PRK12526 PRK12526
RNA polymerase sigma factor; Provisional
64-197 1.11e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 237127 [Multi-domain]  Cd Length: 206  Bit Score: 41.71  E-value: 1.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  64 GNQQDAEDLTQETFMRVFRSLKSYRP--GTFEGWLHRITTNLFLDMVRHRQVIRMEALPENY----DRVPGTLKTPEQaV 137
Cdd:PRK12526  60 GNEAQANELVQETMSNVWRKAHLYNGdkGAATTWVYTVMRNAAFDMLRKIKAKKEQNLGDDIwpieQALAESQSESEE-F 138
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377 138 DDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLR 197
Cdd:PRK12526 139 SDHLMDKQILSYIEKLPEAQQTVVKGVYFQELSQEQLAQQLNVPLGTVKSRLRLALAKLK 198
PRK09047 PRK09047
RNA polymerase factor sigma-70; Validated
63-201 1.79e-04

RNA polymerase factor sigma-70; Validated


Pssm-ID: 236367 [Multi-domain]  Cd Length: 161  Bit Score: 40.34  E-value: 1.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  63 TGNQQDAEDLTQETFMRVfrsLKSYRPGTFEGW---LHRITTNLFLDMVRhRQVIRM-----------------EALPEN 122
Cdd:PRK09047   1 VRDDDAALDIVQDAMIKL---AEKYGDRPAAEWpplFQRILQNRIHDWFR-RQKVRNtwvslfssfsdddddddFDPLET 76
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896182377 123 YDRVPGTLKTPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLE 201
Cdd:PRK09047  77 LDSADEGAESPADKLERAQVLQLIEEAIQKLPARQREAFLLRYWEDMDVAETAAAMGCSEGSVKTHCSRATHALAKALE 155
PRK12525 PRK12525
RNA polymerase sigma factor; Provisional
61-191 2.18e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 139037 [Multi-domain]  Cd Length: 168  Bit Score: 40.31  E-value: 2.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  61 RLTGNQQDAEDLTQETFMRVFR-----SLKSYRpgtfeGWLHRITTNLFLDMVRHRQVIR--MEALPENYDRVPGTLKTP 133
Cdd:PRK12525  28 RQLGCPHSAEDIASETFLQVLAlpdpaSIREPR-----ALLTTIARRLMYEGWRRQDLERayLQSLAEAPEAVQPSPEEQ 102
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 896182377 134 EQAVDDAMLdpdLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMgtvrSRIHR 191
Cdd:PRK12525 103 WMVIETLLA---IDRLLDGLSGKARAAFLMSQLEGLTYVEIGERLGVSL----SRIHQ 153
PRK12530 PRK12530
RNA polymerase sigma factor; Provisional
69-202 9.07e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 237128 [Multi-domain]  Cd Length: 189  Bit Score: 38.98  E-value: 9.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182377  69 AEDLTQETFMRVFRSLKSYR-PGTFEGWLHRITTNLFLDMV--RHRQVIRMEALPEN-----------YDR---VPGTLK 131
Cdd:PRK12530  34 AEDVVQEALVSAYKNADSFKgQSALKTWIFAILKNKIIDLIryRKRFVNESELIEEDspnsffdekghWKPeyyEPSEWQ 113
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896182377 132 TPEQAVDDAMLDPDLEIALAELQPDYRAVVVLCDVVGLTYEEIASTLGLKMGTVRSRIHRARSSLRATLER 202
Cdd:PRK12530 114 EVENTVYKEEFWLIFEACLNHLPAQQARVFMMREYLELSSEQICQECDISTSNLHVLLYRARLQLQACLSK 184
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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