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Conserved domains on  [gi|896182826|ref|WP_049194113|]
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MULTISPECIES: iron ABC transporter permease [Corynebacterium]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 81-386 3.78e-60

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 196.83  E-value: 3.78e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  81 VGPMSLSVGDVVRGIVSPnDVDETTRTVLWKLRLPASVMAVLIGAALSLAGAQMQTILDNPLAEPFTLGISAAAAFGGAA 160
Cdd:COG0609    4 LGAVPISLSDVLRALLGP-DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 161 SIVLGWVIIPHAQ------FNLAAVAwvssviavAIVAAASVWRGSGKESMILLGIGLVFLFQALLALLQYRATTEALQQ 234
Cdd:COG0609   83 AIVLGGGLSALGLplaaflGALLAAL--------LVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 235 IVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAVGINVDRLRIATLIVASLLAATAVAFAGII 314
Cdd:COG0609  155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 896182826 315 GFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVPIGIITAIVGVPFFVGLVFLRK 386
Cdd:COG0609  235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 81-386 3.78e-60

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 196.83  E-value: 3.78e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  81 VGPMSLSVGDVVRGIVSPnDVDETTRTVLWKLRLPASVMAVLIGAALSLAGAQMQTILDNPLAEPFTLGISAAAAFGGAA 160
Cdd:COG0609    4 LGAVPISLSDVLRALLGP-DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 161 SIVLGWVIIPHAQ------FNLAAVAwvssviavAIVAAASVWRGSGKESMILLGIGLVFLFQALLALLQYRATTEALQQ 234
Cdd:COG0609   83 AIVLGGGLSALGLplaaflGALLAAL--------LVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 235 IVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAVGINVDRLRIATLIVASLLAATAVAFAGII 314
Cdd:COG0609  155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 896182826 315 GFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVPIGIITAIVGVPFFVGLVFLRK 386
Cdd:COG0609  235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 70-386 1.59e-48

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 166.55  E-value: 1.59e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826   70 LAVCAFVVATIVGPMSLSVGDVVRGIVSPNDVDEttRTVLWKLRLPASVMAVLIGAALSLAGAQMQTILDNPLAEPFTLG 149
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGDDSLA--ALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  150 ISAAAAFGGAASIVLGWVIiphAQFNLAAVAWVSSVIAVAIVAAASVWR-GSGKESMILLGIGLVFLFQALLALLQYRAT 228
Cdd:pfam01032  79 ISSGAALGAVLAILLGGSL---SLFALPLAAFIGALLAALLVYFLSRGRgGASPLRLILAGIAVSALLSALTSLLLLLLN 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  229 TEALQQIVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAVGINVDRLRIATLIVASLLAATAV 308
Cdd:pfam01032 156 PEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASV 235

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896182826  309 AFAGIIGFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVPIGIITAIVGVPFFvgLVFLRK 386
Cdd:pfam01032 236 AVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFF--IYLLLR 311
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 50-388 4.57e-34

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 128.92  E-value: 4.57e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  50 ARQYRRRSARKIAVIAVLvglavcaFVVATIVgpmSLSVGDVVrgiVSPND-VDETTRTVLWKLRLPASVMAVLIGAALS 128
Cdd:PRK03784   7 ARQQQRRNRRWLLGLSVL-------LLLALLL---SLCAGEQW---ISPGDwLSPRGELFVWQLRLPRTLAVLLVGAALA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 129 LAGAQMQTILDNPLAEPFTLGISAAAAFGGAASIVLGWVIIPHAQFNLAAVAWVSSVIAVAIVAAASVWRGSGKesMILL 208
Cdd:PRK03784  74 VSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPPWALSLCAIAGALLITLILLRFARRHRLSTSR--LLLA 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 209 GIGLVFLFQALLALLQYRATTEALQQIVFWTMGSLQRANWvangIIAAALLIAIPFTIRYAW---ALTVLRLGDARAKAV 285
Cdd:PRK03784 152 GVALGIICSALMTWAVYFSTSLDLRQLMYWMMGGFGGVDW----RQSWLMLALLPVLIWLCCqgrPLNMLALGEISARQL 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 286 GINVDRLRIATLIVASLLAATAVAFAGIIGFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVP 365
Cdd:PRK03784 228 GLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLLLLADIVARLALASAELP 307

                        330       340
                 ....*....|....*....|...
gi 896182826 366 IGIITAIVGVPFFVGLVFLRKRT 388
Cdd:PRK03784 308 IGVVTATLGAPVFIWLLLRSHRA 330
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 118-379 1.80e-28

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 111.88  E-value: 1.80e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 118 VMAVLIGAALSLAGAQMQTILDNPLAEPFTLGISAAAAFGGAASIVLGwviIPHAQFNLAAVAWVSSVIAVAIVAAASVW 197
Cdd:cd06550    2 LAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLG---IGLSNYALGAFAFAGALAIALLVLLLASR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 198 RGSGKESMILLGIGLVFLFQALLALLQYRATTeALQQIVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRL 277
Cdd:cd06550   79 GGLSPSKLILIGIVLSAFFSAGVILISLLSDD-SLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTF 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 278 GDARAKAVGINVDRLRIATLIVASLLAATAVAFAGIIGFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSIT 357
Cdd:cd06550  158 DEDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRT 237

                        250       260
                 ....*....|....*....|..
gi 896182826 358 VVPGVaVPIGIITAIVGVPFFV 379
Cdd:cd06550  238 LLPSE-LPVGPVTALLGAPYFL 258
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 81-386 3.78e-60

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 196.83  E-value: 3.78e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  81 VGPMSLSVGDVVRGIVSPnDVDETTRTVLWKLRLPASVMAVLIGAALSLAGAQMQTILDNPLAEPFTLGISAAAAFGGAA 160
Cdd:COG0609    4 LGAVPISLSDVLRALLGP-DGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 161 SIVLGWVIIPHAQ------FNLAAVAwvssviavAIVAAASVWRGSGKESMILLGIGLVFLFQALLALLQYRATTEALQQ 234
Cdd:COG0609   83 AIVLGGGLSALGLplaaflGALLAAL--------LVYLLARRGGGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 235 IVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAVGINVDRLRIATLIVASLLAATAVAFAGII 314
Cdd:COG0609  155 IVFWLMGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPI 234

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 896182826 315 GFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVPIGIITAIVGVPFFVGLVFLRK 386
Cdd:COG0609  235 GFVGLVVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 70-386 1.59e-48

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 166.55  E-value: 1.59e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826   70 LAVCAFVVATIVGPMSLSVGDVVRGIVSPNDVDEttRTVLWKLRLPASVMAVLIGAALSLAGAQMQTILDNPLAEPFTLG 149
Cdd:pfam01032   1 LLLLLILLSLFIGAVKISPSDVFSALLGGDDSLA--ALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  150 ISAAAAFGGAASIVLGWVIiphAQFNLAAVAWVSSVIAVAIVAAASVWR-GSGKESMILLGIGLVFLFQALLALLQYRAT 228
Cdd:pfam01032  79 ISSGAALGAVLAILLGGSL---SLFALPLAAFIGALLAALLVYFLSRGRgGASPLRLILAGIAVSALLSALTSLLLLLLN 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  229 TEALQQIVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAVGINVDRLRIATLIVASLLAATAV 308
Cdd:pfam01032 156 PEALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASV 235

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896182826  309 AFAGIIGFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVPIGIITAIVGVPFFvgLVFLRK 386
Cdd:pfam01032 236 AVVGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFF--IYLLLR 311
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 50-387 1.03e-37

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 138.45  E-value: 1.03e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  50 ARQYRRRSARKIAVIAVLVGLAVCafvvativgpMSLSVGDVVrgiVSPNDVD-ETTRTVLWKLRLPASVMAVLIGAALS 128
Cdd:COG4139    4 PQRQRRRDRRWLLLLLLLLLLLFV----------LSLCAGEVW---IPPTQWLsEAWQLFVWQLRLPRTLAAVLVGASLA 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 129 LAGAQMQTILDNPLAEPFTLGISAAAAFGGAASIVLGWVIIPHAQFNLAAVAWVSSVIAVAIVAAAsvwRGSGKESMILL 208
Cdd:COG4139   71 VSGAVMQALFENPLAEPGLLGISNGAGVGLVLVVLLGGGLLPPWLLSLAAIAGALLVTLLLLAFAR---RRLSNARLLLI 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 209 GIGLVFLFQALLALLQYRATTEALQQIVFWTMGSLQRANWvANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAVGIN 288
Cdd:COG4139  148 GVALGIICSAIMTWAVYFSSSLDLRQLMYWMMGSFGGVDW-RQLWLLLALLPVLLWLCLQGKPLNLLLLGENQARQLGLS 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 289 VDRLRIATLIVASLLAATAVAFAGIIGFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVPIGI 368
Cdd:COG4139  227 VHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAALLLLADIIARLALSSAELPIGV 306

                        330
                 ....*....|....*....
gi 896182826 369 ITAIVGVPFFVGLVfLRKR 387
Cdd:COG4139  307 VTATLGAPVFIWLL-LRRR 324
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 50-388 9.94e-36

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 133.71  E-value: 9.94e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  50 ARQYRRRSARKIAVIAVLVGLAVCAFVVATIVGPMSLSVGDVVRGIVSPNDvdETTRTVLWKLRLPASVMAVLIGAALSL 129
Cdd:COG4779   12 GRVSLRLRRRALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALLGEGD--PGASFVVLELRLPRALAALLVGAALGL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 130 AGAQMQTILDNPLAEP----FTlgisaaaaFGGAASIVLGWVIIPHAQFNLAAVAWVSSVIAVAIVAAASVWRGSGKESM 205
Cdd:COG4779   90 SGAIFQSLTRNPLASPdiigIT--------AGASAGAVAAIVVLGGSGLAVALGALAGGLATALLVYLLAWRGGVSGYRL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 206 ILLGIGLVFLFQALLALLQYRATTEALQQIVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAV 285
Cdd:COG4779  162 ILVGIGVSAMLTAVNSYLLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAAL 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 286 GINVDRLRIATLIVASLLAATAVAFAGIIGFIGLVGPHIARMLVGeEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVP 365
Cdd:COG4779  242 GVRVERTRLLLLLVAVALAAVATAAAGPIAFVALAAPQIARRLTR-SPGPPLLPSALVGALLLLAADLVAQHLLAPVQLP 320

                        330       340
                 ....*....|....*....|...
gi 896182826 366 IGIITAIVGVPFFVGLVFLRKRT 388
Cdd:COG4779  321 VGVVTGALGGPYLLWLLIRENRR 343
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 50-388 4.57e-34

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 128.92  E-value: 4.57e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  50 ARQYRRRSARKIAVIAVLvglavcaFVVATIVgpmSLSVGDVVrgiVSPND-VDETTRTVLWKLRLPASVMAVLIGAALS 128
Cdd:PRK03784   7 ARQQQRRNRRWLLGLSVL-------LLLALLL---SLCAGEQW---ISPGDwLSPRGELFVWQLRLPRTLAVLLVGAALA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 129 LAGAQMQTILDNPLAEPFTLGISAAAAFGGAASIVLGWVIIPHAQFNLAAVAWVSSVIAVAIVAAASVWRGSGKesMILL 208
Cdd:PRK03784  74 VSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPPWALSLCAIAGALLITLILLRFARRHRLSTSR--LLLA 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 209 GIGLVFLFQALLALLQYRATTEALQQIVFWTMGSLQRANWvangIIAAALLIAIPFTIRYAW---ALTVLRLGDARAKAV 285
Cdd:PRK03784 152 GVALGIICSALMTWAVYFSTSLDLRQLMYWMMGGFGGVDW----RQSWLMLALLPVLIWLCCqgrPLNMLALGEISARQL 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 286 GINVDRLRIATLIVASLLAATAVAFAGIIGFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVP 365
Cdd:PRK03784 228 GLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLLLLADIVARLALASAELP 307

                        330       340
                 ....*....|....*....|...
gi 896182826 366 IGIITAIVGVPFFVGLVFLRKRT 388
Cdd:PRK03784 308 IGVVTATLGAPVFIWLLLRSHRA 330
btuC PRK09535
cobalamin ABC transporter permease BtuC;
64-389 1.86e-32

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 125.25  E-value: 1.86e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  64 IAVLVGLAVCAFVVATIVGPMSLSVGDVVRGIVSPNDVDETTRTVLWKLRLPASVMAVLIGAALSLAGAQMQTILDNPLA 143
Cdd:PRK09535  46 VAVPVGVAVTTHGVPVLSVGLSLPAPDLEYASPFSFAVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMA 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 144 EPFTLGISAAAAFGGAASIVLGwVIIPhaqFNLAAVAWVSSVIAVAIVAAASVWRGSGKESMILLGIGLVFLFQALLALL 223
Cdd:PRK09535 126 DPSIIGVSSGAAVGAVAAIVLP-LAVP---FGLQAAAFAGALVAAFGVYAIATENGRTPVATLLLAGVAVQTFLGAVISY 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 224 QYRATTEALQQIVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAVGINVDRLRIATLIVASLL 303
Cdd:PRK09535 202 LLLHSGESLRRAVYWLMGHLHGSTWSDVEVALPVVVVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVV 281

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 304 AATAVAFAGIIGFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITvvPGVAVPIGIITAIVGVPFFvgLVF 383
Cdd:PRK09535 282 TAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLPTSALAGASFLVATDTVARS--GPAEVPVGIVTAALGAPFF--LYL 357


                 ....*.
gi 896182826 384 LRKRTV 389
Cdd:PRK09535 358 LRTREV 363
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 118-379 1.80e-28

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 111.88  E-value: 1.80e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 118 VMAVLIGAALSLAGAQMQTILDNPLAEPFTLGISAAAAFGGAASIVLGwviIPHAQFNLAAVAWVSSVIAVAIVAAASVW 197
Cdd:cd06550    2 LAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLG---IGLSNYALGAFAFAGALAIALLVLLLASR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 198 RGSGKESMILLGIGLVFLFQALLALLQYRATTeALQQIVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRL 277
Cdd:cd06550   79 GGLSPSKLILIGIVLSAFFSAGVILISLLSDD-SLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTF 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 278 GDARAKAVGINVDRLRIATLIVASLLAATAVAFAGIIGFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSIT 357
Cdd:cd06550  158 DEDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRT 237

                        250       260
                 ....*....|....*....|..
gi 896182826 358 VVPGVaVPIGIITAIVGVPFFV 379
Cdd:cd06550  238 LLPSE-LPVGPVTALLGAPYFL 258
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
55-383 4.39e-26

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 110.31  E-value: 4.39e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  55 RRSARKIAVIAVLVGLAVCAFVVATIVGPMSLSVGDVVRGIVSPnDVDETTRTVLWKLRLPASVMAVLIGAALSLAGAQM 134
Cdd:PRK10577   5 MSRRRARLPALLLALLLLLALALTLTQLSAALPLSQWLQALWGP-DADDLEQLLLHYSRLPRLAIALLVGAALGLAGALL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 135 QTILDNPLAEPFTLGISAAAAFGGAASIVLGWVIIPHAQFNLA------------AVAWVssviavaivaaasvwRGSGK 202
Cdd:PRK10577  84 QQVLRNPLASPTTLGVAAGAQLALVLATLFAPALLALASQLAAfaggllaaalvfALAGG---------------KRLSP 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 203 ESMILLG--IGLVFLFQALLALLQYRattEALQQIVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDA 280
Cdd:PRK10577 149 LRLVLAGmvVSLYLGALTTLLLLFNE---QYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDD 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 281 RAKAVGINVDRLRIATLIVASLLAATAVAFAGIIGFIGLVGPHIARMLVGEE--QRFFAPASMAAGAALLAAAHAVSITV 358
Cdd:PRK10577 226 VARSLGLAVSLTRLAALALAVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRlrARLPLSPLIGALLLLLTDQLVRLLAG 305

                        330       340
                 ....*....|....*....|....*
gi 896182826 359 VPGVAVPIGIITAIVGVPFFVGLVF 383
Cdd:PRK10577 306 VGGELLPTGAVTALIGAPLLLWLLP 330
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
83-388 3.34e-25

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 104.39  E-value: 3.34e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  83 PMSLSVGDVVRGIVsPNDVDETTRTVLWKLRLPASVMAVLIGAALSLAGAQMQTILDNPLAEPFTLGISAAAAFGGAASI 162
Cdd:PRK11228  22 AIPISAADALNALL-PGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTS 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 163 VLgwVIIPHAQFNLA-------AVAWVSSVIAVAIvaaasvWR-GSGKESMILLGIGLVFLFQALLALLQYRATTEAlQQ 234
Cdd:PRK11228 101 AL--SPTPFAGYSLAfiaacggGLSWLLVMTAGGG------WRhTHDRNRLILAGIALSALCMALTRITLLLAEDHA-YG 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 235 IVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAVGINVDRLRIATLIVASLLAATAVAFAGII 314
Cdd:PRK11228 172 IFYWLAGGVSHARWQEVWQLLPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPV 251

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896182826 315 GFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVPIGIITAIVGVPFFVGLVflRKRT 388
Cdd:PRK11228 252 AFIGLLVPHLARFWIGYDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWLA--RRRG 323
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
59-381 1.31e-24

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 102.82  E-value: 1.31e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  59 RKIAVIAVLVGLAVCAFVVATIVGPMSLSVGDVVRGIvspnDVDETTRTVLWKLRLPASVMAVLIGAALSLAGAQMQTIL 138
Cdd:PRK09777   1 MKIALVIFITLALAGCALLSLRMGVIPLPWRALLTDW----QAGDEHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 139 DNPLAEPFTLGISAAAAFGGAASIVLgwviiphaqFNLAAVAWV-SSVIAVAIVAAASVWRGSGKESMILLGIGLVFLFQ 217
Cdd:PRK09777  77 RNPLASPDILGVNHAASLASVGALLL---------FPSLPVMWLpLLAFIGGMAGLILLKMLAGTHQPMKLALTGVALSA 147

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 218 ALLALLQYRATTEALQ--QIVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAVGINVDRLRIA 295
Cdd:PRK09777 148 LWASLTDYLMLSRPQDinNALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFW 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 296 TLIVASLLAATAVAFAGIIGFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVPIGIITAIVGV 375
Cdd:PRK09777 228 ALLLAVALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGA 307


                 ....*.
gi 896182826 376 PFFVGL 381
Cdd:PRK09777 308 PWFFWL 313
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
48-387 6.73e-24

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 103.77  E-value: 6.73e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  48 DSARQYRRRSARKIAVIAVLVGLAVCAfvvativgpmSLSVGDVVRGIvspNDVDETTRTVLWKLRLPASVMAVLIGAAL 127
Cdd:PRK10577 345 DRVAARRRRVLAWLLALGLLLLLALVV----------ALSFGRDAHGW---NWLSGQLLDALLPLRLPRLLAALLAGAML 411

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 128 SLAGAQMQTILDNPLAEPFTLGISAAAAFGGaasiVLGWVIIPHAQFNLAAVAWVSSVIAVAIVAAASVWRGS-GKESMI 206
Cdd:PRK10577 412 AVAGTLLQRLTRNPLASPEVLGISSGAGLGV----VLALFLVPGAGFGWLLAAALLGALAALALILLLARRGGfAPERLL 487

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 207 LLGIGLVFLFQALLALLQYRATTEAlQQIVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAVG 286
Cdd:PRK10577 488 LTGIALSALFTALIQLLLASGDPRA-AQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARALG 566

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 287 INVDRLRIATLIVASLLAATAVAFAGIIGFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGVAVPI 366
Cdd:PRK10577 567 LPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFPYQIPA 646

                        330       340
                 ....*....|....*....|.
gi 896182826 367 GIITAIVGVPFFVGLvfLRKR 387
Cdd:PRK10577 647 GLLAALIGAPYFLWL--LRRS 665
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
55-387 8.47e-16

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 77.82  E-value: 8.47e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  55 RRSARKIAVIAVLVGLAVcAFVVATIVGPMSLSVGDVVRGIVSpnDVDETTRTVLWKLRLPASVMAVLIGAALSLAGAQM 134
Cdd:PRK10441   5 VAVTRAIAVPGLLLLLII-ATALSLLIGAKSLPASVVLEALSG--TCQSADCTIVLDARLPRTLAGLLAGGALGLAGALM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 135 QTILDNPLAEPFTLGISAAAAFGGAASIVLGWVIIPHAQFNLAAVAwvssVIAVAIVAAASVWRGSGKESMILLGIGLVF 214
Cdd:PRK10441  82 QTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAG----ALVASLIVAFTGSQGGGQLSPVRLTLAGVA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 215 LFQALLALLQYRATT--EALQQIVFWTMGSLQRANWVANGIIAAALLIAIPFTIRYAWALTVLRLGDARAKAVGINVDRL 292
Cdd:PRK10441 158 LAAVLEGLTSGIALLnpDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVART 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 293 RIATLIVASLLAATAVAFAGIIGFIGLVGPHIARMLVGEEQRFFAPASMAAGAALLAAAHAVSITVVPGvAVPIGIITAI 372
Cdd:PRK10441 238 QLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRLLVPG-ELRVSVVSAF 316

                        330
                 ....*....|....*
gi 896182826 373 VGVPFFVGLVFLRKR 387
Cdd:PRK10441 317 IGAPVLIFLVRRKTR 331
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
54-330 1.16e-15

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 77.06  E-value: 1.16e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826  54 RRRSARKIAVIAVLVGLAVCAFVVATIVGPMSLSVGDVVRGIVSpnDVDETTRTVLWKLRLPASVMAVLIGAALSLAGAQ 133
Cdd:PRK10440   2 IYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMG--DAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 134 MQTILDNPLAEPFTLGISAAAAFGGAASIVLgwviIPHAQFNLAAVAWVSSVIAVAIVAAASVWRGSGKESMILLGIGLV 213
Cdd:PRK10440  80 FQSLMRNPLGSPDVMGFNTGAWSGVLVAMVL----FGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVR 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896182826 214 FLFQALLALLQYRATTEALQQIVFWTMGSLqranwvaNGIIAAALLIAIPFTIRY---AWALT----VLRLGDARAKAVG 286
Cdd:PRK10440 156 AMLVAFNTWLLLKASLETALTAGLWNAGSL-------NGLTWAKTSPSAPIIILMliaAALLVrrmrLLEMGDDTACALG 228

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 896182826 287 INVDRLRIATLIVASLLAATAVAFAGIIGFIGLVGPHIARMLVG 330
Cdd:PRK10440 229 VSVERSRLLLMLVAVVLTAAATALAGPISFIALVAPHIARRLSG 272
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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