NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|896405248|ref|WP_049342649|]
View 

DNA polymerase III subunit gamma/tau [Metamycoplasma hominis]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
3-667 0e+00

DNA polymerase III subunits gamma and tau; Validated


:

Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 755.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   3 LTNKYLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHnQSDILKPCEEC 82
Cdd:PRK07133   1 MRMKYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSH-KTDLLEPCQEC 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  83 IKNVDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK07133  80 IENVNNSLDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVH 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKvIKKEVVEQ 242
Cdd:PRK07133 160 KIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNK-ITLKNVEE 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 243 LFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSLVS-TDFKILLQIKIDD 321
Cdd:PRK07133 239 LFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLVKEFIIFNKTKDNSLLEyYSEEDLEKLKIDD 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 322 AKAHYYIETLIDQLHSIAVSDSPEDYFEILLLKLCNYLSPKEEYKNSAVMPKISNEEFNNFNSQEKQVINKNNIYKSLDL 401
Cdd:PRK07133 319 DFAYKFIEILFDLLKDLKISDNPNDTLEILIIKLLALSELEEEDENEIKFKKIEENSIDNLDIKEKKIENENDIEGKSDT 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 402 SSIANGFNANNSTIQNSSDNNSTEDLANNSKKIDDLLEKTAEIYSLDQTSEFEVADISNQIISNNQISIDSNVDNQETAD 481
Cdd:PRK07133 399 KNLEEGFETKDNKNKNSSFINKTENILTNSPLKDELLEKTTEIINIENPQEFEFGQIGNDIISTEIAQLDENQNLIDTGE 478
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 482 L----------------QISENWKDLVNEDLISKENSENK-----------------HVPLETIIDCLLIKQYLKNNMLN 528
Cdd:PRK07133 479 FdlennfsnsfnpengnKIDENINETFDTSTISANLSENKtnfaqsfnnkdtnlinsEIPIDLIKDTITINNSQKNVKKN 558
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 529 DGRSNFTDIDAIKYGMLSQKITDKNEIN--------------------------ILSDFKIIFSTNDFILLTC---DIDE 579
Cdd:PRK07133 559 GNKDYLSVEEVINLIMLAIKFHSQNQVEykklvqnwnknlplfeydvefmeiahFLKDLKILASSDNFILFSSkrdEIDE 638
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 580 KVYDLNINSHNENIMSALNKVFDRYLYAYAITKGEILEAKKYWKENINEIRAKKVKPLEDLNlKYNKTVQKDVAWAQEIF 659
Cdd:PRK07133 639 LIIKLNKNNYKVNFQNFLEKIFGGPKHIFAISKKLINEAKIYWKAINNTKKSVVIKPLEKPK-KYEKTSVSKENLEKEIF 717

                 ....*...
gi 896405248 660 GDKFKLNK 667
Cdd:PRK07133 718 GDKFTKKK 725
 
Name Accession Description Interval E-value
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
3-667 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 755.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   3 LTNKYLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHnQSDILKPCEEC 82
Cdd:PRK07133   1 MRMKYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSH-KTDLLEPCQEC 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  83 IKNVDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK07133  80 IENVNNSLDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVH 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKvIKKEVVEQ 242
Cdd:PRK07133 160 KIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNK-ITLKNVEE 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 243 LFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSLVS-TDFKILLQIKIDD 321
Cdd:PRK07133 239 LFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLVKEFIIFNKTKDNSLLEyYSEEDLEKLKIDD 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 322 AKAHYYIETLIDQLHSIAVSDSPEDYFEILLLKLCNYLSPKEEYKNSAVMPKISNEEFNNFNSQEKQVINKNNIYKSLDL 401
Cdd:PRK07133 319 DFAYKFIEILFDLLKDLKISDNPNDTLEILIIKLLALSELEEEDENEIKFKKIEENSIDNLDIKEKKIENENDIEGKSDT 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 402 SSIANGFNANNSTIQNSSDNNSTEDLANNSKKIDDLLEKTAEIYSLDQTSEFEVADISNQIISNNQISIDSNVDNQETAD 481
Cdd:PRK07133 399 KNLEEGFETKDNKNKNSSFINKTENILTNSPLKDELLEKTTEIINIENPQEFEFGQIGNDIISTEIAQLDENQNLIDTGE 478
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 482 L----------------QISENWKDLVNEDLISKENSENK-----------------HVPLETIIDCLLIKQYLKNNMLN 528
Cdd:PRK07133 479 FdlennfsnsfnpengnKIDENINETFDTSTISANLSENKtnfaqsfnnkdtnlinsEIPIDLIKDTITINNSQKNVKKN 558
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 529 DGRSNFTDIDAIKYGMLSQKITDKNEIN--------------------------ILSDFKIIFSTNDFILLTC---DIDE 579
Cdd:PRK07133 559 GNKDYLSVEEVINLIMLAIKFHSQNQVEykklvqnwnknlplfeydvefmeiahFLKDLKILASSDNFILFSSkrdEIDE 638
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 580 KVYDLNINSHNENIMSALNKVFDRYLYAYAITKGEILEAKKYWKENINEIRAKKVKPLEDLNlKYNKTVQKDVAWAQEIF 659
Cdd:PRK07133 639 LIIKLNKNNYKVNFQNFLEKIFGGPKHIFAISKKLINEAKIYWKAINNTKKSVVIKPLEKPK-KYEKTSVSKENLEKEIF 717

                 ....*...
gi 896405248 660 GDKFKLNK 667
Cdd:PRK07133 718 GDKFTKKK 725
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
7-356 1.53e-147

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 432.38  E-value: 1.53e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248    7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC---- 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDG--EPCNECesck 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   83 -IKNvDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDP 161
Cdd:TIGR02397  79 eINS-GSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEP 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  162 QKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCaNKVIKKEVVE 241
Cdd:TIGR02397 158 HKIPATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFG-NGKITYEDVN 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  242 QLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKT----RDQSLVSTDFKILLQI 317
Cdd:TIGR02397 237 ELLGLVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTpsnlLAVLESEQEFLKELAL 316
                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 896405248  318 KIDDAKAHYYIETLIDQLHSIAVSDSPEDYFEILLLKLC 356
Cdd:TIGR02397 317 KLSLEFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
16-356 7.57e-125

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 373.37  E-value: 7.57e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  16 PKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC-----IKNvDRNL 90
Cdd:COG2812    6 PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTG--EPCGECescraIAA-GSHP 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  91 DIIEIDA-ASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETIL 169
Cdd:COG2812   83 DVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTIL 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 170 SRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHvaiycankvikkevvEQLFGIVNI 249
Cdd:COG2812  163 SRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQ---------------AIAFGLLDR 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 250 DNK-IELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQ-SLVSTDFKILLQ---IKIDDAKA 324
Cdd:COG2812  228 RELlLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAeLLVNEDERERLQelaRRLSPERL 307
                        330       340       350
                 ....*....|....*....|....*....|..
gi 896405248 325 HYYIETLIDQLHSIAVSDSPEDYFEILLLKLC 356
Cdd:COG2812  308 LRAIQILLEARRELERNVNPRLALEMLLLRLA 339
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
24-178 4.86e-41

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 146.97  E-value: 4.86e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   24 GQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC--IKNVDRNL--DIIEIDAAS 99
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDD--LPCGQCrsCRRIESGNhpDLVIIEPEG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  100 NT-GIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFK 178
Cdd:pfam13177  79 QSiKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFK 158
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
180-245 1.03e-14

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 69.07  E-value: 1.03e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896405248 180 MTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKvIKKEVVEQLFG 245
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGR-VTLDDVREMLG 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
45-180 8.00e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 48.91  E-value: 8.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248    45 YLFCGPHGNGKTSTAKVFANTINCLHNQSdILKPCEE--CIKNVDRNLDIIEIDAASNTGIDDIRELKEKIKhlptQSKY 122
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGV-IYIDGEDilEEVLDQLLLIIVGGKKASGSGELRLRLALALAR----KLKP 79
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896405248   123 KIYIIDEVHMLSKAAFNALL--------KTIEDPPSHIIFILATTDPQKIPETILSRvqRFNFKLM 180
Cdd:smart00382  80 DVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRR--RFDRRIV 143
 
Name Accession Description Interval E-value
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
3-667 0e+00

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 755.89  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   3 LTNKYLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHnQSDILKPCEEC 82
Cdd:PRK07133   1 MRMKYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCSH-KTDLLEPCQEC 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  83 IKNVDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK07133  80 IENVNNSLDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVH 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKvIKKEVVEQ 242
Cdd:PRK07133 160 KIPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNK-ITLKNVEE 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 243 LFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSLVS-TDFKILLQIKIDD 321
Cdd:PRK07133 239 LFGLVSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLVKEFIIFNKTKDNSLLEyYSEEDLEKLKIDD 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 322 AKAHYYIETLIDQLHSIAVSDSPEDYFEILLLKLCNYLSPKEEYKNSAVMPKISNEEFNNFNSQEKQVINKNNIYKSLDL 401
Cdd:PRK07133 319 DFAYKFIEILFDLLKDLKISDNPNDTLEILIIKLLALSELEEEDENEIKFKKIEENSIDNLDIKEKKIENENDIEGKSDT 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 402 SSIANGFNANNSTIQNSSDNNSTEDLANNSKKIDDLLEKTAEIYSLDQTSEFEVADISNQIISNNQISIDSNVDNQETAD 481
Cdd:PRK07133 399 KNLEEGFETKDNKNKNSSFINKTENILTNSPLKDELLEKTTEIINIENPQEFEFGQIGNDIISTEIAQLDENQNLIDTGE 478
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 482 L----------------QISENWKDLVNEDLISKENSENK-----------------HVPLETIIDCLLIKQYLKNNMLN 528
Cdd:PRK07133 479 FdlennfsnsfnpengnKIDENINETFDTSTISANLSENKtnfaqsfnnkdtnlinsEIPIDLIKDTITINNSQKNVKKN 558
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 529 DGRSNFTDIDAIKYGMLSQKITDKNEIN--------------------------ILSDFKIIFSTNDFILLTC---DIDE 579
Cdd:PRK07133 559 GNKDYLSVEEVINLIMLAIKFHSQNQVEykklvqnwnknlplfeydvefmeiahFLKDLKILASSDNFILFSSkrdEIDE 638
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 580 KVYDLNINSHNENIMSALNKVFDRYLYAYAITKGEILEAKKYWKENINEIRAKKVKPLEDLNlKYNKTVQKDVAWAQEIF 659
Cdd:PRK07133 639 LIIKLNKNNYKVNFQNFLEKIFGGPKHIFAISKKLINEAKIYWKAINNTKKSVVIKPLEKPK-KYEKTSVSKENLEKEIF 717

                 ....*...
gi 896405248 660 GDKFKLNK 667
Cdd:PRK07133 718 GDKFTKKK 725
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
7-356 1.53e-147

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 432.38  E-value: 1.53e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248    7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC---- 82
Cdd:TIGR02397   1 YQVLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDG--EPCNECesck 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   83 -IKNvDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDP 161
Cdd:TIGR02397  79 eINS-GSSLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEP 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  162 QKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCaNKVIKKEVVE 241
Cdd:TIGR02397 158 HKIPATILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFG-NGKITYEDVN 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  242 QLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKT----RDQSLVSTDFKILLQI 317
Cdd:TIGR02397 237 ELLGLVDDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTpsnlLAVLESEQEFLKELAL 316
                         330       340       350
                  ....*....|....*....|....*....|....*....
gi 896405248  318 KIDDAKAHYYIETLIDQLHSIAVSDSPEDYFEILLLKLC 356
Cdd:TIGR02397 317 KLSLEFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
7-463 9.68e-143

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 427.36  E-value: 9.68e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC---- 82
Cdd:PRK05563   3 YQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNCLNPPDG--EPCNECeick 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  83 -IKNvDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDP 161
Cdd:PRK05563  81 aITN-GSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEP 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 162 QKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKViKKEVVE 241
Cdd:PRK05563 160 HKIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKV-TYEDAL 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 242 QLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEwIIFNKTRDQ-------SLVSTDFKIL 314
Cdd:PRK05563 239 EVTGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRD-LLLVKTSPEleildesTENDELFKEL 317
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 315 LQiKIDDAKAHYYIETLIDQLHSIAVSDSPEDYFEILLLKLCNYLSPKEEYKNS--AVMPKISN--EEFNNFNSQEKQVI 390
Cdd:PRK05563 318 SE-KLDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLCEQAAASPEYDTEleVLLQRVEQleQELKQLKAQPVGVA 396
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 896405248 391 NKNNIYKSLDLSSIANGFNANNSTIQNSSDNNSTEDLANNSKKIDDLLE----KTAEIYSLDQTSEfEVADISNQII 463
Cdd:PRK05563 397 PEQKEKKKEKKKNKKKKYKVPRGKIYKVLKEATRQDLELLKNVWGEILEslkaQRKSLRALLVNSE-PVAASEDTVV 472
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
16-356 7.57e-125

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 373.37  E-value: 7.57e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  16 PKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC-----IKNvDRNL 90
Cdd:COG2812    6 PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENGPTG--EPCGECescraIAA-GSHP 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  91 DIIEIDA-ASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETIL 169
Cdd:COG2812   83 DVIEIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTIL 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 170 SRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHvaiycankvikkevvEQLFGIVNI 249
Cdd:COG2812  163 SRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQ---------------AIAFGLLDR 227
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 250 DNK-IELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQ-SLVSTDFKILLQ---IKIDDAKA 324
Cdd:COG2812  228 RELlLDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAeLLVNEDERERLQelaRRLSPERL 307
                        330       340       350
                 ....*....|....*....|....*....|..
gi 896405248 325 HYYIETLIDQLHSIAVSDSPEDYFEILLLKLC 356
Cdd:COG2812  308 LRAIQILLEARRELERNVNPRLALEMLLLRLA 339
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
5-505 8.36e-102

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 323.45  E-value: 8.36e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   5 NKYLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDILKPCEECik 84
Cdd:PRK14948   1 MAYEPLHHKYRPQRFDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNCLNSDKPTPEPCGKC-- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 NVDRN------LDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILAT 158
Cdd:PRK14948  79 ELCRAiaagnaLDVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLAT 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 159 TDPQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYcaNKVIKKE 238
Cdd:PRK14948 159 TDPQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQLSLL--PGPITPE 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 239 VVEQLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIF---NKTRDQSLVSTDF-KIL 314
Cdd:PRK14948 237 AVWDLLGAVPEQDLLNLLKALASNDPESLLDSCRQLLDRGREPLAILQGLAAFYRDLLLAktaPNRPDLVAVSQQTwDEL 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 315 LQIkiddakAHYY-IETLIdQLHS--------IAVSDSPEDYFEILLLKLCnylspkeeykNSAVMPKISNEEFNNFNSQ 385
Cdd:PRK14948 317 CKL------AKQInLERIL-QWQQhlkgseyqLKNSTQPRLWLEVTLLGLL----------PSAFISEIANASAPANPTP 379
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 386 EKQVINKNNIyksldlSSIANGFNANNSTIQNSSDNNSTEDLANNSKKIDDLLEKTAEiySLDQTSEFEVADISNQIISN 465
Cdd:PRK14948 380 APNPSPPPAP------IQPSAPKTKQAATTPSPPPAKASPPIPVPAEPTEPSPTPPAN--AANAPPSLNLEELWQQILAK 451
                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....
gi 896405248 466 NQ--------------ISIDSNVdnqetADLQISENWKDLVNEDLISKENSENK 505
Cdd:PRK14948 452 LElpstrmllsqqaelVSLDSNR-----AVIAVSPNWLGMVQSRKPLLEQAFAK 500
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
7-355 6.05e-97

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 306.75  E-value: 6.05e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC--IK 84
Cdd:PRK14953   3 YIPFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEG--EPCGKCenCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 NVDRNL--DIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK14953  81 EIDKGSfpDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYD 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKViKKEVVEQ 242
Cdd:PRK14953 161 KIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKV-TIKVVEE 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 243 LFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINIL---INDLI-NILKEWIIfnKTRDQSLVSTDFKILLQIK 318
Cdd:PRK14953 240 FLGIVSQESVRKFLNLLLESDVDEAIKFLRTLEEKGYNLNKFwkqLEEEIrNILLNKSL--KNPEEVFQVEDFYRKLEKP 317
                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 896405248 319 IddaKAHYYIETLIDQLHSIAVSDSPEDYFEILLLKL 355
Cdd:PRK14953 318 L---EALLYLEDVINKAFSEARTRDPLRAYELAILKL 351
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
7-248 6.61e-97

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 309.36  E-value: 6.61e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSdiLKPCEECIKNV 86
Cdd:PRK14965   3 YLVLARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCEQGLT--AEPCNVCPPCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  87 D----RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK14965  81 EitegRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKVIKKEVVEq 242
Cdd:PRK14965 161 KVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAE- 239

                 ....*.
gi 896405248 243 LFGIVN 248
Cdd:PRK14965 240 LLGVVD 245
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
9-316 7.96e-96

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 306.74  E-value: 7.96e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   9 ALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDiLKPCEEC-----I 83
Cdd:PRK14950   5 VLYRKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTNDPK-GRPCGTCemcraI 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  84 KNvDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQK 163
Cdd:PRK14950  84 AE-GSAVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHK 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 164 IPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKvIKKEVVEQL 243
Cdd:PRK14950 163 VPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGE-ISLSQVQSL 241
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896405248 244 FGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSL--VSTDFKILLQ 316
Cdd:PRK14950 242 LGISGDEEVKALAEALLAKDLKAALRTLNAVAADGADLRQFTRDLVEYLRQVMLLNSGADRSLldLTADEKAALQ 316
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
6-288 7.92e-91

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 294.76  E-value: 7.92e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   6 KYLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSD--ILKPCEECI 83
Cdd:PRK14971   3 NYIVSARKYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQNLTADgeACNECESCV 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  84 K-NVDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK14971  83 AfNEQRSYNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKH 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKVIKKEVVEQ 242
Cdd:PRK14971 163 KILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVIEN 242
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 896405248 243 LfGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDL 288
Cdd:PRK14971 243 L-NILDYDYYFRLTDALLAGKVSDSLLLFDEILNKGFDGSHFITGL 287
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
7-292 7.72e-90

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 289.34  E-value: 7.72e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINClhNQSDILKPCEECIKNV 86
Cdd:PRK14969   3 YQVLARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNC--ETGVTATPCGVCSACL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  87 D----RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK14969  81 EidsgRFVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKVIKKEVVEQ 242
Cdd:PRK14969 161 KIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAM 240
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 896405248 243 LfGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINIL 292
Cdd:PRK14969 241 L-GAIDQDYLFALLEALLAQDGAALLAIADAMEERSLSFDAALQDLAALL 289
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
7-292 1.83e-89

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 291.77  E-value: 1.83e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC--IK 84
Cdd:PRK07994   3 YQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLNCETGITA--TPCGECdnCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 NVD--RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK07994  81 EIEqgRFVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHvAIYCANKVIKKEVVEQ 242
Cdd:PRK07994 161 KLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQ-AIASGNGQVTTDDVSA 239
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 896405248 243 LFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINIL 292
Cdd:PRK07994 240 MLGTLDDDQALSLLEALVEGDGERVMALINQLAERGPDWEGLLVELLELL 289
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
9-318 1.06e-87

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 284.23  E-value: 1.06e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   9 ALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEECIK---- 84
Cdd:PRK08451   3 ALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCEQGPSS--TPCDTCIQcqsa 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 NVDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKI 164
Cdd:PRK08451  81 LENRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 165 PETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKVIKKEVVEQLf 244
Cdd:PRK08451 161 PATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADML- 239
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 896405248 245 GIVNiDNKIE-LLNYMSMHDINKTLNLARELfsQGIDINILINDLINILKEwIIFNKTRDQSLVSTD--FKILLQIK 318
Cdd:PRK08451 240 GLLD-PSKLEdFFQAILNQDKEKLFELLKEL--EDYEAEMVLDEMMLFLKE-KFLSKDSEFSILLYErfFRILSSAK 312
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
13-517 1.57e-87

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 284.36  E-value: 1.57e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  13 KYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINClhNQSDILKPCEEC-----IKNvD 87
Cdd:PRK06647   9 KRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNC--VNGPTPMPCGECsscksIDN-D 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  88 RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPET 167
Cdd:PRK06647  86 NSLDVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPAT 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 168 ILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCaNKVIKKEVVEQLFGIV 247
Cdd:PRK06647 166 IKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFS-DSDITLEQIRSKMGLT 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 248 NIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEwIIFNK--TRDQSLVSTDFKILLQiKIDDAKAH 325
Cdd:PRK06647 245 GDEFLEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLLDCIEFFRE-LLFLKhgIKNEAFIGIKAERLPE-KLREFDLS 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 326 YY---IETLIDQLHSIAVSDSPEDYFEIL---LLKLCNYLSPKEeyknsaVMPKISNEEfnnfnsqekqvinknniyksl 399
Cdd:PRK06647 323 QIeraISVLLETYRDLQFSVNPRYELEINfskILRLKDYVPNHE------LIKQIQDLE--------------------- 375
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 400 dlSSIANGFNANNSTIQNSSDNNSTEDLANNSKKIdDLLEKTAEIYSLDqtsefevadisnqiiSNNQISIDSNVDNQET 479
Cdd:PRK06647 376 --SKLLEHAAPDSCNFDVGSDNESTDDLSPIPIDP-PLKAELPEIRSLE---------------PDESTKEDEPLKTKID 437
                        490       500       510
                 ....*....|....*....|....*....|....*...
gi 896405248 480 ADLQISENWKDLVNEDLISKENSENKHVPLETIIDCLL 517
Cdd:PRK06647 438 SDMLSTESWDDEIDEIFIEVRDNFDRSNDNEEIKESFI 475
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
9-323 4.12e-85

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 275.49  E-value: 4.12e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   9 ALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSdiLKPCEEC--IKNV 86
Cdd:PRK14962   3 ALYRKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKG--VEPCNECraCRSI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  87 DRN--LDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKI 164
Cdd:PRK14962  81 DEGtfMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 165 PETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYcANKVIKKEVVEQLF 244
Cdd:PRK14962 161 PPTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKF-SEGKITLETVHEAL 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 245 GIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSLVSTDF-KILLQIKIDDAK 323
Cdd:PRK14962 240 GLIPIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEVLIQQAIEDLVEDLERERANDIIQVSRQLlNILREIKFAEEK 319
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
7-289 3.01e-83

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 269.72  E-value: 3.01e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDiLKPCEECI--K 84
Cdd:PRK06305   4 YQVSSRKYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCQNPTED-QEPCNQCAscK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 NVD--RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK06305  83 EISsgTSLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIH 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVaIYCANKVIKKEVVEQ 242
Cdd:PRK06305 163 KIPGTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYV-VGLFPKSLDPDSVAK 241
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 896405248 243 LFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLI 289
Cdd:PRK06305 242 ALGLLSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHFLHDLT 288
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
5-443 1.13e-82

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 272.87  E-value: 1.13e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   5 NKYLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLH-NQSDILKPCEEC- 82
Cdd:PRK05896   1 MSEITFYRKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNpKDGDCCNSCSVCe 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  83 IKNVDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK05896  81 SINTNQSVDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYcANKVIKKEVVEQ 242
Cdd:PRK05896 161 KIPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTF-KNSEIDIEDINK 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 243 LFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSLVS------TDFKILLQ 316
Cdd:PRK05896 240 TFGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLLIDLLVYQKTKNINLLKklskeqLKTLNLEK 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 317 IKID--DAKAHYYIETLIDQLHSIAVSDSPEDYFEILLLKLCNY-----------LSPKEEYKNSAVMPKISNEEFNNFN 383
Cdd:PRK05896 320 QKLLsiEFNTNFLLNNFVSLINRLKASVNQVFEFEIYLYKIINAnpdklenkkieISIKPEKKTINNSQIITTKKINIVE 399
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896405248 384 SQEKQVINKNNIYKSLDLSSIANGFNANNSTIQNSSDNNSTE-----DLANNSKKIDDLLEKTAE 443
Cdd:PRK05896 400 ESNKNSVHFDTLYKTKIFYHKKKINQNNKEQDIKKEELLEKEfvkksEKIPKNDELLDNLELAKQ 464
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
7-350 5.49e-81

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 271.20  E-value: 5.49e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC--IK 84
Cdd:PRK08691   3 YQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHG--EPCGVCqsCT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 NVD--RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK08691  81 QIDagRYVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKViKKEVVEQ 242
Cdd:PRK08691 161 KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKV-AENDVRQ 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 243 LFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILkewiifnktrdQSLVstdfkiLLQiKIDDA 322
Cdd:PRK08691 240 MIGAVDKQYLYELLTGIINQDGAALLAKAQEMAACAVGFDNALGELAILL-----------QQLA------LIQ-AVPSA 301
                        330       340       350
                 ....*....|....*....|....*....|.
gi 896405248 323 KAHYYIETliDQLHSIAVSDSPED---YFEI 350
Cdd:PRK08691 302 LAHDDPDS--DILHRLAQTISGEQiqlYYQI 330
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
8-429 2.99e-78

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 257.79  E-value: 2.99e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   8 LALyrKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINC-LHNQSDILKPCEEC--IK 84
Cdd:PRK14964   3 LAL--KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCsNGPTSDPCGTCHNCisIK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 NVDrNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKI 164
Cdd:PRK14964  81 NSN-HPDVIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKI 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 165 PETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYcANKVIKKEVVEQLF 244
Cdd:PRK14964 160 PVTIISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIY-SNNKISEKSVRDLL 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 245 GIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILiNDLINILKEWIIFNKTRDQSLVSTDfKILLQIKIDDAKA 324
Cdd:PRK14964 239 GCVDKHILEDLVEAILLGDAQSALNVFRELCNTSNPVIIL-EGMLQIIYEICYFSITKEIDFLLGE-DLITRIKSLKIGS 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 325 HYYI----ETLIDQLHSIAVSDSPEDYFEILLLKLCnYL----SPKE-------EYKNSAVMPKISNEEFNNFNS----Q 385
Cdd:PRK14964 317 TIFLsrlwQMLLKGIQEVKSSTCVKQAAEMMIIRLC-YLsdlpSPQQiikkilsKSVEQAPRQIKVNNKQQNYDFdkllQ 395
                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 896405248 386 EKQVINKNNIYKSL--DLSSIANGFNANNSTIQNSS-DNNSTEDLAN 429
Cdd:PRK14964 396 LLKSNNMIDLYNQLcsSLQEIDCKSDYTLNIKANSQlDSNFCNDLKN 442
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
7-307 8.81e-78

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 260.26  E-value: 8.81e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSD------ILKPCE 80
Cdd:PRK14954   3 YQVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDpvylqeVTEPCG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  81 ECIKNVD----RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFIL 156
Cdd:PRK14954  83 ECESCRDfdagTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIF 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 157 ATTDPQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYC----AN 232
Cdd:PRK14954 163 ATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAFSvgseAE 242
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896405248 233 KVIKKEVVEQLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSLV 307
Cdd:PRK14954 243 KVIAYQGVAELLNYIDDEQFFDVTDAIAENDAVKMLEVARFVIDNGYDEQDFLEKLIEHFRNFLVLYNLRSTRLI 317
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
9-294 9.43e-78

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 257.08  E-value: 9.43e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   9 ALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINClhnQSDILKPCEEC-----I 83
Cdd:PRK14963   3 ALYQRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNC---SGEDPKPCGECesclaV 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  84 KNvDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQK 163
Cdd:PRK14963  80 RR-GAHPDVLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEK 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 164 IPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHvaIYCANKVIKKEVVEQL 243
Cdd:PRK14963 159 MPPTILSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLER--LLALGTPVTRKQVEEA 236
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 896405248 244 FGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKE 294
Cdd:PRK14963 237 LGLPPQERLRGIAAALAQGDAAEALSGAAQLYRDGFAARTLVEGLLEAFRA 287
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
7-288 1.27e-77

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 259.06  E-value: 1.27e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCL----HNQ--SDILKPCE 80
Cdd:PRK09111  11 YRVLARKYRPQTFDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEgpdgDGGptIDLCGVGE 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  81 EC--IKNvDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILAT 158
Cdd:PRK09111  91 HCqaIME-GRHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFAT 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 159 TDPQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHvAIYCANKVIKKE 238
Cdd:PRK09111 170 TEIRKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQ-AIAHGAGEVTAE 248
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 896405248 239 VVEQLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDL 288
Cdd:PRK09111 249 AVRDMLGLADRARVIDLFEALMRGDVAAALAEFRAQYDAGADPVVVLTDL 298
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
7-292 5.14e-77

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 258.11  E-value: 5.14e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINC--LHNQSDIL-KPCEECI 83
Cdd:PRK14951   3 YLVLARKYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCqgPDGQGGITaTPCGVCQ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  84 KNVD----RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATT 159
Cdd:PRK14951  83 ACRDidsgRFVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATT 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 160 DPQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHvAIYCANKVIKKEV 239
Cdd:PRK14951 163 DPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQ-AIAFGSGQLQEAA 241
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 896405248 240 VEQLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINIL 292
Cdd:PRK14951 242 VRQMLGSVDRSHVFRLIDALAQGDGRTVVETADELRLNGLSAASTLEEMAAVL 294
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
7-292 6.54e-77

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 259.81  E-value: 6.54e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCL--HNQSDIL-KPCEEC- 82
Cdd:PRK12323   3 YQVLARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCTgaDGEGGITaQPCGQCr 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  83 -IKNVD--RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATT 159
Cdd:PRK12323  83 aCTEIDagRFVDYIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATT 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 160 DPQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKVIkKEV 239
Cdd:PRK12323 163 DPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVS-EEA 241
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 896405248 240 VEQLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINIL 292
Cdd:PRK12323 242 VRGMLGAIDQSYLVRLLDALAAEDGAALLAIADEMAGRSLSFAGALQDLASLL 294
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
12-297 1.03e-76

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 249.79  E-value: 1.03e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  12 RKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilkpceecikNVDRNLD 91
Cdd:PRK14970   9 RKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQPGYDDP----------NEDFSFN 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  92 IIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSR 171
Cdd:PRK14970  79 IFELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSR 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 172 VQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKVIKKEVVEQLfGIVNIDN 251
Cdd:PRK14970 159 CQIFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENL-NILDYDT 237
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 896405248 252 KIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWII 297
Cdd:PRK14970 238 YINVTDLILENKIPELLLAFNEILRKGFDGHHFIAGLASHFRDLMV 283
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
7-389 6.18e-76

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 257.28  E-value: 6.18e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEECIK-- 84
Cdd:PRK14960   2 YQVLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTS--TPCEVCATck 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 --NVDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK14960  80 avNEGRFIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQ 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKVIKKEVVEQ 242
Cdd:PRK14960 160 KLPITVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEM 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 243 LfGIvnIDNKI--ELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSLVSTD---FKILLQI 317
Cdd:PRK14960 240 L-GL--IDRTIiyDLILAVHQNQREKVSQLLLQFRYQALDVSLVLDQLISTLHELALLQYLPELGLKYSEeinAKILQLS 316
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896405248 318 KIDDAK-AHYYIETLIDQLHSIAVSDSPEDYFEILLLKLCNY--LSPKEEYKNSAVMPkiSNEEFNNFNSQEKQV 389
Cdd:PRK14960 317 KLISAQdLQLYYQIACKGRSDLQLAVTQEQGFEMCVLRLLAFrpLAPNEILVSEPVQQ--NGQAEVGLNSQAQTA 389
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
7-307 1.04e-75

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 248.27  E-value: 1.04e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSD------ILKPCE 80
Cdd:PRK14955   3 YQVIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRMIDDadylqeVTEPCG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  81 ECIKNVD----RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFIL 156
Cdd:PRK14955  83 ECESCRDfdagTSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIF 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 157 ATTDPQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCAN---- 232
Cdd:PRK14955 163 ATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAFSVEsege 242
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896405248 233 KVIKKEVVEQLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSLV 307
Cdd:PRK14955 243 GSIRYDKVAELLNYIDDEHFFAVTDAVADGDAVAMLDVAQFVIRNGYDEQDFLEKLIEHLRNFLVVHNLRSTRLV 317
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
7-264 2.65e-71

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 248.87  E-value: 2.65e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINClhNQSDILKPCEECIKNV 86
Cdd:PRK14949   3 YQVLARKWRPATFEQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNC--EQGVTATPCGVCSSCV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  87 D----RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK14949  81 EiaqgRFVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHvAIYCANKVIKKEVVEQ 242
Cdd:PRK14949 161 KLPVTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQ-AIAFGGGQVMLTQVQT 239
                        250       260
                 ....*....|....*....|....
gi 896405248 243 LFGivNIDNK--IELLNYMSMHDI 264
Cdd:PRK14949 240 MLG--SIDEQhvIALLKALTDADI 261
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
8-224 3.13e-71

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 246.82  E-value: 3.13e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   8 LALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDIlkPCEECIKNVD 87
Cdd:PRK07764   3 LALYRRYRPATFAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCVEGPTST--PCGECDSCVA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  88 ------RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDP 161
Cdd:PRK07764  81 lapggpGSLDVTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEP 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 896405248 162 QKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIAD 224
Cdd:PRK07764 161 DKVIGTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLD 223
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
8-224 6.44e-70

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 238.24  E-value: 6.44e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   8 LALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLhnQSDILKPC---EECI- 83
Cdd:PRK14952   1 MALYRKYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCA--QGPTATPCgvcESCVa 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  84 --KNVDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDP 161
Cdd:PRK14952  79 laPNGPGSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEP 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 896405248 162 QKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIAD 224
Cdd:PRK14952 159 EKVLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLD 221
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
4-292 1.00e-69

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 235.52  E-value: 1.00e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   4 TNKYLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLH--NQSDILKPCEE 81
Cdd:PRK06645   5 SNQYIPFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSAliTENTTIKTCEQ 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  82 CIKNVDRN----LDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILA 157
Cdd:PRK06645  85 CTNCISFNnhnhPDIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFA 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 158 TTDPQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCAN--KVI 235
Cdd:PRK06645 165 TTEVQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSAKsdNII 244
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 896405248 236 KKEVVEQLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINIL 292
Cdd:PRK06645 245 SPQVINQMLGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFIESVSDFI 301
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
3-292 2.03e-69

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 234.07  E-value: 2.03e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   3 LTNKYLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINClhNQSDILKPCEEC 82
Cdd:PRK14956   1 MSGTHEVLSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNC--ENPIGNEPCNEC 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  83 IKNVD----RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILAT 158
Cdd:PRK14956  79 TSCLEitkgISSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILAT 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 159 TDPQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKVIKKE 238
Cdd:PRK14956 159 TEFHKIPETILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVK 238
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 896405248 239 vVEQLFGIVNIDNKIELLNYMSMHDIN-KTLNLARELFSQGIDINILINDLINIL 292
Cdd:PRK14956 239 -IRKMIGYHGIEFLTSFIKSLIDPDNHsKSLEILESLYQEGQDIYKFLWDSIEFT 292
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
7-292 1.07e-68

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 240.14  E-value: 1.07e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC--IK 84
Cdd:PRK07003   3 YQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTS--QPCGVCraCR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 NVD--RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK07003  81 EIDegRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKViKKEVVEQ 242
Cdd:PRK07003 161 KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEV-TETAVSG 239
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 896405248 243 LFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINIL 292
Cdd:PRK07003 240 MLGALDQTYMVRLLDALAAGDGPEILAVADEMALRSLSFSTALQDLASLL 289
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
10-378 2.75e-66

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 226.54  E-value: 2.75e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  10 LYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSdiLKPCEEC--IKNVD 87
Cdd:PRK14958   6 LARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKGVS--ANPCNDCenCREID 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  88 --RNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIP 165
Cdd:PRK14958  84 egRFPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLP 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 166 ETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKVIKKEvVEQLFG 245
Cdd:PRK14958 164 VTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIAD-VKTMLG 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 246 IVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFnKTRDQSLVSTDFKILLQIKI----DD 321
Cdd:PRK14958 243 TIEPLLLFDILEALAAKAGDRLLGCVTRLVEQGVDFSNALADLLSLLHQIAII-QTVPEALIENDSEQLRQLAKlldrED 321
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 896405248 322 AKAHYYIeTLIDQlHSIAVSDSPEDYFEILLLKLCNYLS------PKEEYKNSAVMPKISNEE 378
Cdd:PRK14958 322 VQLFYQI-GLIGQ-RDLAYSPTPQTGFEMTLLRMLAFYPsaanaiPETESKEAVVTPTPKSSE 382
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
7-353 3.25e-66

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 221.99  E-value: 3.25e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEECI--K 84
Cdd:PRK14961   3 YQILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITS--NPCRKCIicK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 NVDRN--LDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQ 162
Cdd:PRK14961  81 EIEKGlcLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 163 KIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHvAIYCANKVIKKEVVEQ 242
Cdd:PRK14961 161 KIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEH-AINLGKGNINIKNVTD 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 243 LFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILkewiifnktrdqslvstdFKILLQIKIDDA 322
Cdd:PRK14961 240 MLGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSIGIEWENILIEMLRFL------------------HHISMSQSFPKI 301
                        330       340       350
                 ....*....|....*....|....*....|....
gi 896405248 323 KAHYYIETLIDQLHSIAVSDSPED---YFEILLL 353
Cdd:PRK14961 302 WNTIFIKNYKNQIQKIAQNNKKTNiqlCYQILLN 335
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
9-355 1.23e-65

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 227.64  E-value: 1.23e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   9 ALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQS-DILKPCEECIKNVD 87
Cdd:PRK14959   5 SLTARYRPQTFAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTgEPCNTCEQCRKVTQ 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  88 RN-LDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPE 166
Cdd:PRK14959  85 GMhVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKFPV 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 167 TILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKvIKKEVVEQLFGI 246
Cdd:PRK14959 165 TIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESR-LTIDGARGVLGL 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 247 VNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSLVSTDFK-------ILLQIKI 319
Cdd:PRK14959 244 AGQELFLRLMEALAAQDCLGVANVVRELLDRGVDMGFFLRELVATWRNLFMLRQAGEAALASLDLPedearqwLGWAKRF 323
                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 896405248 320 DDAKAHYYIETLIDQLHSIAVSDSPEDYFEILLLKL 355
Cdd:PRK14959 324 EPAHIHACWQMTLEGQRRVLTSLEPAMALELLLLNL 359
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
7-476 6.41e-64

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 221.11  E-value: 6.41e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   7 YLALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHN-QSDILKPCEECIK- 84
Cdd:PRK14957   3 YQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGvTAEPCNKCENCVAi 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 NVDRNLDIIEIDAASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKI 164
Cdd:PRK14957  83 NNNSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKI 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 165 PETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKvIKKEVVEQLF 244
Cdd:PRK14957 163 PVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGE-LKQAQIKQML 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 245 GIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILINDLINILKEWIIFNKTRDQSLVS-TDFKILLQI--KIDD 321
Cdd:PRK14957 242 GIIDSEEVYSIINAIIDNDPKAILPAIKNLALTESSADAVLDRIAEIWFACCIYSFTQSLDAVNdIDVDIINNIlaKISI 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 322 AKAHYYIETLIDQLHSIAVSDSPEDYFEILLLKLCNY----LSPKEEYKNSAVMPKISNEEF----NNFNSQEKQVINKN 393
Cdd:PRK14957 322 EQAHFLYQLTITAKKDIALAPNFETGVTMAILRLIAFqkknLIDKTQTSKSNISPIVSKNDInllkNTFKSEQPKQTVKA 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 394 NIYKSldlssiaNGFNANNSTIQNSSD------------NNSTEDLANNSKKIDDLLEkTAEIYsLDQTSEfEVADISNQ 461
Cdd:PRK14957 402 VVAQN-------NDSTASENTQEQSLDkkwfnllnriklKGFTKTLAFNSHLISDNSE-TFVIH-LNEDAK-KILELDPQ 471
                        490
                 ....*....|....*
gi 896405248 462 IISNNQISIDSNVDN 476
Cdd:PRK14957 472 SIAKLQASISEYLNN 486
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
25-315 4.55e-49

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 173.24  E-value: 4.55e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  25 QDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEECIK---NVDRNLDIIEI--DAAS 99
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGG--KACGQCHSrlmAAGNHPDLLELnpEEKS 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 100 NT-GIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFK 178
Cdd:COG0470   79 DQiGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFR 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 179 LMTIETLVSQLKDifnkENIeyEDDAINVIAKLGNGSLRDSLSIADHVAIYcankvikKEVVEQLFGIVNIDNKIELLNY 258
Cdd:COG0470  159 PPSEEEALAWLRE----EGV--DEDALEAILRLAGGDPRAAINLLQALAGR-------KELLEDLAALLSRDRALELLDA 225
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 896405248 259 MSMHDINKTLNLARELFSQGIDINILINDLINILKEWiifNKTRDQSLVSTDFKILL 315
Cdd:COG0470  226 LLKAEALELLDWLLKWLLDNLPLEYAGEDLARAYEAL---SEADRRLGRYANDRLLL 279
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
24-178 4.86e-41

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 146.97  E-value: 4.86e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   24 GQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC--IKNVDRNL--DIIEIDAAS 99
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDD--LPCGQCrsCRRIESGNhpDLVIIEPEG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  100 NT-GIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFK 178
Cdd:pfam13177  79 QSiKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFK 158
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
30-217 3.58e-39

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 142.77  E-value: 3.58e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   30 TTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC--IKNVDRNL--DIIEIDAASNT-GID 104
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGG--EPCGEChsCRLIEAGNhpDLHRLEPEGQSiKVD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  105 DIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFKLMTIET 184
Cdd:TIGR00678  80 QVRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEA 159
                         170       180       190
                  ....*....|....*....|....*....|...
gi 896405248  185 LVsqlkDIFNKENIEYEDDAInvIAKLGNGSLR 217
Cdd:TIGR00678 160 LL----QWLIRQGISEEAAEL--LLALAGGSPG 186
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
25-191 8.91e-27

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 111.56  E-value: 8.91e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  25 QDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEECiKNVDR-------NLDIIEIDA 97
Cdd:PRK08058  11 QPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGV--EPCGTC-TNCKRidsgnhpDVHLVAPDG 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  98 ASnTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNF 177
Cdd:PRK08058  88 QS-IKKDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVVEF 166
                        170
                 ....*....|....
gi 896405248 178 KLMTIETLVSQLKD 191
Cdd:PRK08058 167 RPLPPESLIQRLQE 180
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
13-264 1.88e-25

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 107.77  E-value: 1.88e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  13 KYRPKIFDDIKGQDHIVTTLKNIILNNKLSHaYLFCGPHGNGKTSTAKVFANTincLH-----------NQSDILKPCEE 81
Cdd:PRK12402   8 KYRPALLEDILGQDEVVERLSRAVDSPNLPH-LLVQGPPGSGKTAAVRALARE---LYgdpwennftefNVADFFDQGKK 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  82 CIKNVDRNLDIIEIDAASNTG-IDDIRE-LKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATT 159
Cdd:PRK12402  84 YLVEDPRFAHFLGTDKRIRSSkIDNFKHvLKEYASYRPLSADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIATR 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 160 DPQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIycANKVIKKEV 239
Cdd:PRK12402 164 QPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAAL--AAGEITMEA 241
                        250       260
                 ....*....|....*....|....*.
gi 896405248 240 VEQLFGIVNIDNKIE-LLNYMSMHDI 264
Cdd:PRK12402 242 AYEALGDVGTDEVIEsLLDAAEAGDF 267
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
19-215 1.91e-25

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 107.29  E-value: 1.91e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  19 FDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINClhnqSDILKPCEECiKNVDRN-LDIIEI-- 95
Cdd:PRK07399   3 FANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALCFIEGLLS----QGSPSKNIRR-RLEEGNhPDLLWVep 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  96 -----------DAASNTG----------IDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDpPSHIIF 154
Cdd:PRK07399  78 tyqhqgklitaSEAEEAGlkrkappqirLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEE-PGNGTL 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896405248 155 ILATTDPQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAInvIAkLGNGS 215
Cdd:PRK07399 157 ILIAPSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPEL--LA-LAQGS 214
rfc PRK00440
replication factor C small subunit; Reviewed
13-281 2.57e-25

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 107.27  E-value: 2.57e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  13 KYRPKIFDDIKGQDHIVTTLKNIILNNKLSHaYLFCGPHGNGKTSTAKVFAntinclhnqsdilkpceeciknvdRNL-- 90
Cdd:PRK00440  10 KYRPRTLDEIVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTTAALALA------------------------RELyg 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  91 -----DIIEIDAASNTGIDDIRElkeKIKHL-----PTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTD 160
Cdd:PRK00440  65 edwreNFLELNASDERGIDVIRN---KIKEFartapVGGAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNY 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 161 PQKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYcaNKVIKKEVV 240
Cdd:PRK00440 142 SSKIIDPIQSRCAVFRFSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAAT--GKEVTEEAV 219
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 896405248 241 EQLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQ----GIDI 281
Cdd:PRK00440 220 YKITGTARPEEIREMIELALNGDFTEAREKLRDLMIDyglsGEDI 264
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
13-245 3.96e-25

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 108.25  E-value: 3.96e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  13 KYRPKIFDDIKGQDHIV---TTLKNIILNNKLSHAyLFCGPHGNGKTSTAKVFANTINclhnqsdilkpceeciknvdrn 89
Cdd:PRK13342   5 RMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSM-ILWGPPGTGKTTLARIIAGATD---------------------- 61
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  90 LDIIEIDAAsNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDppSHIIFILATT-DPQ-KIPET 167
Cdd:PRK13342  62 APFEALSAV-TSGVKDLREVIEEARQRRSAGRRTILFIDEIHRFNKAQQDALLPHVED--GTITLIGATTeNPSfEVNPA 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 168 ILSRVQRFNFKLMT---IETLVSQ-LKDIfNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIycANKVIKKEVVEQL 243
Cdd:PRK13342 139 LLSRAQVFELKPLSeedIEQLLKRaLEDK-ERGLVELDDEALDALARLANGDARRALNLLELAAL--GVDSITLELLEEA 215

                 ..
gi 896405248 244 FG 245
Cdd:PRK13342 216 LQ 217
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
18-173 8.40e-21

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 94.98  E-value: 8.40e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  18 IFDDIKGQDHIVTTLKNI---------ILNNKLSHAYLFCGPHGNGKTSTAKVFANTINClhnQSDILKPCEEC--IKNV 86
Cdd:PRK07940   3 VWDDLVGQEAVVAELRAAaraaradvaAAGSGMTHAWLFTGPPGSGRSVAARAFAAALQC---TDPDEPGCGECraCRTV 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  87 --DRNLDIIEIDAASNT-GIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQK 163
Cdd:PRK07940  80 laGTHPDVRVVAPEGLSiGVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPED 159
                        170
                 ....*....|
gi 896405248 164 IPETILSRVQ 173
Cdd:PRK07940 160 VLPTIRSRCR 169
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
15-243 2.09e-18

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 88.19  E-value: 2.09e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  15 RPKIFDDIKGQDHIV---TTLKNIILNNKLsHAYLFCGPHGNGKTSTAKVFANTINclhnqsdilkpceeciknvdrnLD 91
Cdd:COG2256   20 RPRTLDEVVGQEHLLgpgKPLRRAIEAGRL-SSMILWGPPGTGKTTLARLIANATD----------------------AE 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  92 IIEIDAASnTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDppSHIIFILATTdpqkipET---- 167
Cdd:COG2256   77 FVALSAVT-SGVKDIREVIEEARERRAYGRRTILFVDEIHRFNKAQQDALLPHVED--GTITLIGATT------ENpsfe 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 168 ----ILSRVQRFNFKLMT---IETLVSQ-LKDI---FNKENIEYEDDAINVIAKLGNGSLRDSLS---IADHVAIYCANK 233
Cdd:COG2256  148 vnsaLLSRCRVFVLKPLSeedLEQLLERaLADDergLGGYKLELDDEALEALARLADGDARRALNaleLAVLSAPPDGVI 227
                        250
                 ....*....|
gi 896405248 234 VIKKEVVEQL 243
Cdd:COG2256  228 EITLELVEEA 237
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
40-199 1.17e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 81.67  E-value: 1.17e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  40 KLSHAYLFCGPHGNGKTSTAKVFANTINClhNQSDILKPCEEC-------IKNVDRNLDIIEIDAASNTGIDDIRELKEK 112
Cdd:PRK05707  20 RHPHAYLLHGPAGIGKRALAERLAAALLC--EAPQGGGACGSCkgcqllrAGSHPDNFVLEPEEADKTIKVDQVRELVSF 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 113 IKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFKL----MTIETLVSQ 188
Cdd:PRK05707  98 VVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLpsneESLQWLQQA 177
                        170
                 ....*....|.
gi 896405248 189 LKDIFNKENIE 199
Cdd:PRK05707 178 LPESDERERIE 188
PRK04195 PRK04195
replication factor C large subunit; Provisional
13-217 1.66e-16

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 82.66  E-value: 1.66e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  13 KYRPKIFDDIKGQDHIVTTLKNII---LNNKLSHAYLFCGPHGNGKTSTAKVFANTINC----LhNQSDilkpceecikn 85
Cdd:PRK04195   7 KYRPKTLSDVVGNEKAKEQLREWIeswLKGKPKKALLLYGPPGVGKTSLAHALANDYGWevieL-NASD----------- 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  86 vDRNLDIIE--IDAASNTGIddirelkekikhLpTQSKYKIYIIDEVHMLSKAA----FNALLKTIEDPPSHIIfiLATT 159
Cdd:PRK04195  75 -QRTADVIErvAGEAATSGS------------L-FGARRKLILLDEVDGIHGNEdrggARAILELIKKAKQPII--LTAN 138
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 896405248 160 DPQKIP-ETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLR 217
Cdd:PRK04195 139 DPYDPSlRELRNACLMIEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLR 197
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
103-200 1.71e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 80.61  E-value: 1.71e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 103 IDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFKLmti 182
Cdd:PRK05917  77 IETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRSLSIHIPM--- 153
                         90
                 ....*....|....*...
gi 896405248 183 etlvsQLKDIFNKENIEY 200
Cdd:PRK05917 154 -----EEKTLVSKEDIAY 166
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
19-199 2.04e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 77.77  E-value: 2.04e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  19 FDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANtinclhnqsDILKpceecIKNVDRNLDIIE--ID 96
Cdd:PRK05564   3 FHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKEIAL---------KILG-----KSQQREYVDIIEfkPI 68
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  97 AASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFN 176
Cdd:PRK05564  69 NKKSIGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYK 148
                        170       180
                 ....*....|....*....|...
gi 896405248 177 FKLMTIETLVSQLKDIFNKENIE 199
Cdd:PRK05564 149 LNRLSKEEIEKFISYKYNDIKEE 171
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
40-179 5.13e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 76.54  E-value: 5.13e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  40 KLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDILKPCEECIK-NVDRNLDIIEIdAASNTG--------IDDIRELK 110
Cdd:PRK08769  24 RLGHGLLICGPEGLGKRAVALALAEHVLASGPDPAAAQRTRQLIAaGTHPDLQLVSF-IPNRTGdklrteivIEQVREIS 102
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896405248 111 EKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFKL 179
Cdd:PRK08769 103 QKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRLEFKL 171
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
43-176 6.06e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 76.31  E-value: 6.06e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  43 HAYLFCGPHGNGKTSTAKVFANTINCLHNQSDilKPCEEC----------------IKNVDrNLDIieidaasntGIDDI 106
Cdd:PRK06871  25 HALLFKADSGLGTEQLIRALAQWLMCQTPQGD--QPCGQChschlfqagnhpdfhiLEPID-NKDI---------GVDQV 92
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 107 RELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFN 176
Cdd:PRK06871  93 REINEKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQTWL 162
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
180-245 1.03e-14

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 69.07  E-value: 1.03e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896405248 180 MTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKvIKKEVVEQLFG 245
Cdd:cd18137    1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGR-VTLDDVREMLG 65
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
40-225 4.69e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 73.92  E-value: 4.69e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  40 KLSHAYLFCGPHGNGKTSTAKVFANTI--NCLHNQ--SDILKP-------------CEECIKNVDRNLDiiEIDAASNTG 102
Cdd:PRK09112  43 KLHHALLFEGPEGIGKATLAFHLANHIlsHPDPAEapETLADPdpaspvwrqiaqgAHPNLLHITRPFD--EKTGKFKTA 120
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 103 I--DDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFKLM 180
Cdd:PRK09112 121 ItvDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTIRSRCQPISLKPL 200
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 896405248 181 TIETLVSQLKDIFNKENIeyEDDAINVIAKLGNGSLRDSLSIADH 225
Cdd:PRK09112 201 DDDELKKALSHLGSSQGS--DGEITEALLQRSKGSVRKALLLLNY 243
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
23-179 6.69e-14

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 69.48  E-value: 6.69e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  23 KGQDHIVTTLKNIILNNKLSHaYLFCGPHGNGKTSTAKVFANTInclhnqsdilkpceeciknVDRNLDIIEIDAASNTG 102
Cdd:cd00009    1 VGQEEAIEALREALELPPPKN-LLLYGPPGTGKTTLARAIANEL-------------------FRPGAPFLYLNASDLLE 60
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 103 IDDIREL-----KEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIED------PPSHIIFILATTDP--QKIPETIL 169
Cdd:cd00009   61 GLVVAELfghflVRLLFELAEKAKPGVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATNRPllGDLDRALY 140
                        170
                 ....*....|.
gi 896405248 170 SR-VQRFNFKL 179
Cdd:cd00009  141 DRlDIRIVIPL 151
PLN03025 PLN03025
replication factor C subunit; Provisional
13-220 1.28e-13

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 72.45  E-value: 1.28e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  13 KYRPKIFDDIKGQDHIVTTLKNIILNNKLSHaYLFCGPHGNGKTStakvfanTINCLHNQsdILKPceeCIKNVdrnldI 92
Cdd:PLN03025   6 KYRPTKLDDIVGNEDAVSRLQVIARDGNMPN-LILSGPPGTGKTT-------SILALAHE--LLGP---NYKEA-----V 67
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  93 IEIDAASNTGIDDIRelkEKIK-------HLPTqSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIP 165
Cdd:PLN03025  68 LELNASDDRGIDVVR---NKIKmfaqkkvTLPP-GRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKII 143
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 896405248 166 ETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSL 220
Cdd:PLN03025 144 EPIQSRCAIVRFSRLSDQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQAL 198
44 PHA02544
clamp loader, small subunit; Provisional
8-211 7.22e-13

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 70.02  E-value: 7.22e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   8 LALYRKYRPKIFDDIKGQDHIVTTLKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINClhnqsdilkpceeciknvd 87
Cdd:PHA02544   9 FMWEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSPGTGKTTVAKALCNEVGA------------------- 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  88 rnlDIIEIDAASNtGIDDIR-ELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKT-IEDPPSHIIFILATTDPQKIP 165
Cdd:PHA02544  70 ---EVLFVNGSDC-RIDFVRnRLTRFASTVSLTGGGKVIIIDEFDRLGLADAQRHLRSfMEAYSKNCSFIITANNKNGII 145
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 896405248 166 ETILSRVQRFNF-------KLMTIETLVSQLKDIFNKENIEYEDdaiNVIAKL 211
Cdd:PHA02544 146 EPLRSRCRVIDFgvptkeeQIEMMKQMIVRCKGILEAEGVEVDM---KVLAAL 195
PRK13341 PRK13341
AAA family ATPase;
15-223 1.38e-12

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 70.85  E-value: 1.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  15 RPKIFDDIKGQDHIVTT---LKNIILNNKLSHAyLFCGPHGNGKTSTAKVFANTINClhnqsdilkpceeciknvdrnlD 91
Cdd:PRK13341  23 RPRTLEEFVGQDHILGEgrlLRRAIKADRVGSL-ILYGPPGVGKTTLARIIANHTRA----------------------H 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  92 IIEIDAASnTGIDDIR-ELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDppSHIIFILATTD-PQ-KIPETI 168
Cdd:PRK13341  80 FSSLNAVL-AGVKDLRaEVDRAKERLERHGKRTILFIDEVHRFNKAQQDALLPWVEN--GTITLIGATTEnPYfEVNKAL 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896405248 169 LSRVQRFNFKLMTIETL---VSQ-LKDI---FNKENIEYEDDAINVIAKLGNG---SLRDSLSIA 223
Cdd:PRK13341 157 VSRSRLFRLKSLSDEDLhqlLKRaLQDKergYGDRKVDLEPEAEKHLVDVANGdarSLLNALELA 221
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
35-178 2.29e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 68.12  E-value: 2.29e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  35 IILNNKLSHAYLFCGPHGNgkTSTAKVFANTINCLhNQSDILkPCEECiknvdRNLDIIEIDAASNTGI----------D 104
Cdd:PRK07276  17 ILEQDRLNHAYLFSGDFAS--FEMALFLAQSLFCE-QKEGVL-PCGHC-----RSCRLIEQGEFSDVTViepqgqviktD 87
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896405248 105 DIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFK 178
Cdd:PRK07276  88 TIRELVKNFSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHFP 161
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
19-218 2.17e-11

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 64.52  E-value: 2.17e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  19 FDDIKGQDHIVTTLKNII-----------LNNKLSHAYLFCGPHGNGKTSTAKVFANTInclhnqsdilkpceeciknvd 87
Cdd:COG1223    1 LDDVVGQEEAKKKLKLIIkelrrrenlrkFGLWPPRKILFYGPPGTGKTMLAEALAGEL--------------------- 59
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  88 rNLDIIEI-----------DAASNtgiddIRELKEKIKHLPTqskykIYIIDEVHML------------SKAAFNALLKT 144
Cdd:COG1223   60 -KLPLLTVrldsligsylgETARN-----LRKLFDFARRAPC-----VIFFDEFDAIakdrgdqndvgeVKRVVNALLQE 128
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896405248 145 IEDPPSHIIFILATTDPQKIPETILSRVQ-RFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRD 218
Cdd:COG1223  129 LDGLPSGSVVIAATNHPELLDSALWRRFDeVIEFPLPDKEERKEILELNLKKFPLPFELDLKKLAKKLEGLSGAD 203
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
45-178 4.02e-11

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 61.07  E-value: 4.02e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   45 YLFCGPHGNGKTSTAKVFANTINclhnqsdilkpceeciknvdrnLDIIEIDAASNTGI------DDIRELKEKIKHLPT 118
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELG----------------------APFIEISGSELVSKyvgeseKRLRELFEAAKKLAP 58
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896405248  119 qskyKIYIIDEVHMLSKA-----------AFNALLKTIEDP---PSHIIFILATTDPQKIPETILSRVQRFNFK 178
Cdd:pfam00004  59 ----CVIFIDEIDALAGSrgsggdsesrrVVNQLLTELDGFtssNSKVIVIAATNRPDKLDPALLGRFDRIIEF 128
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
12-195 7.22e-11

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 64.55  E-value: 7.22e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  12 RKYRPKIFDDIKGQDHIVTTLKNIIL----NNKLSHAY--------LFCGPHGNGKTSTAKVFANTINclhnqsdilkpc 79
Cdd:COG0464  149 LELREAILDDLGGLEEVKEELRELVAlplkRPELREEYglppprglLLYGPPGTGKTLLARALAGELG------------ 216
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  80 eeciknvdrnLDIIEIDAAS-----------NtgiddIRELKEKIKHL-PTqskykIYIIDEVHML-----------SKA 136
Cdd:COG0464  217 ----------LPLIEVDLSDlvskyvgetekN-----LREVFDKARGLaPC-----VLFIDEADALagkrgevgdgvGRR 276
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 137 AFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQR-FNFKLMTIEtlvsQLKDIFNK 195
Cdd:COG0464  277 VVNTLLTEMEELRSDVVVIAATNRPDLLDPALLRRFDEiIFFPLPDAE----ERLEIFRI 332
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
40-175 7.84e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 63.74  E-value: 7.84e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  40 KLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDiLKPCEECI----------------------KNVDRNLDIIEIDA 97
Cdd:PRK08699  19 RRPNAWLFAGKKGIGKTAFARFAAQALLCETPAPG-HKPCGECMschlfgqgshpdfyeitplsdePENGRKLLQIKIDA 97
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896405248  98 asntgiddIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRF 175
Cdd:PRK08699  98 --------VREIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKM 167
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
99-171 1.96e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 62.78  E-value: 1.96e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 896405248  99 SNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSR 171
Cdd:PRK07993  86 SSLGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSR 158
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
32-335 2.43e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 62.05  E-value: 2.43e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  32 LKNIILNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDILKPCEECIKNVDRNLDIIEIDaasntgiDDIRELKE 111
Cdd:PRK07132   8 LDNSATQNKISHSFLLKSNYNEDIDEKILYFLNKFNNLQITNLNEQELPANIILFDIFDKDLSKS-------EFLSAINK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 112 KIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFKLMtietlvSQLKD 191
Cdd:PRK07132  81 LYFSSFVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEP------DQQKI 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 192 IFNKENIEYEDDAINVIAKLGNGslrdslsiadhvaIYCANKVIKKEVVEQLFGIVNIDNKIELLNYMSMHDINKTLNLA 271
Cdd:PRK07132 155 LAKLLSKNKEKEYNWFYAYIFSN-------------FEQAEKYINKESENLLKKFEEALNKSLKEKYELILFLNKKLTKE 221
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896405248 272 RELFsqgidinilINDLINILKEWIIFNKTRDQSLVSTDFKILLQ-IKIDDAKAHYYIETLIDQL 335
Cdd:PRK07132 222 NALF---------LLKLLKFFFKSIFANKKKKNPKNIKVAFSKKKkFKIEFFELITIIDEFLNSL 277
PRK04132 PRK04132
replication factor C small subunit; Provisional
91-240 8.50e-10

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 62.16  E-value: 8.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  91 DIIEIDAASNTGIDDIRE-LKEKIKHLPT-QSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETI 168
Cdd:PRK04132 598 NFLELNASDERGINVIREkVKEFARTKPIgGASFKIIFLDEADALTQDAQQALRRTMEMFSSNVRFILSCNYSSKIIEPI 677
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 896405248 169 LSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAiyCANKVIKKEVV 240
Cdd:PRK04132 678 QSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQAAA--ALDDKITDENV 747
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
40-190 2.22e-09

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 59.43  E-value: 2.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  40 KLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDILKPCEECIKNVDRN---LDII--EIDAASNTgIDDIRELKeKIK 114
Cdd:PRK06090  23 RIPGALLLQSDEGLGVESLVELFSRALLCQNYQSEACGFCHSCELMQSGNhpdLHVIkpEKEGKSIT-VEQIRQCN-RLA 100
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 896405248 115 HLPTQ-SKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFKLMTIETLVSQLK 190
Cdd:PRK06090 101 QESSQlNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPSTAQAMQWLK 177
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
37-175 2.56e-09

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 59.39  E-value: 2.56e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  37 LNNKLSHAYLFCGPHGNGKTSTAKVFANTINCLHNQSDiLKPCEECI--------KNVDRNLDIIEI-DAASNTGIDDIR 107
Cdd:PRK06964  16 LRARLPHALLLHGQAGIGKLDFAQHLAQGLLCETPQPD-GEPCGTCAacnwfaqgNHPDYRIVRPEAlAAEAPGAADEAK 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 108 ELKEKIKHLPTQSKYKIYIIDEVHMLSK------------------------AAFNALLKTIEDPPSHIIFILATTDPQK 163
Cdd:PRK06964  95 EADADEGGKKTKAPSKEIKIEQVRALLDfcgvgthrggarvvvlypaealnvAAANALLKTLEEPPPGTVFLLVSARIDR 174
                        170
                 ....*....|..
gi 896405248 164 IPETILSRVQRF 175
Cdd:PRK06964 175 LLPTILSRCRQF 186
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
83-323 1.61e-08

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 56.41  E-value: 1.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  83 IKNVDRNLDIIEIDAASntgiDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSK--AAFNALLKTIEDPPSHIIFILATTD 160
Cdd:COG1466   28 ALAEDDGFNRTRLDGAE----TDWAELLDEAQTLSLFGERRLVIVRNAEFLKKpgEGLEALEAYLANPPPDTVLVLTAGK 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 161 P---QKIPETILSRVQRFNFKLMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYC-ANKVIK 236
Cdd:COG1466  104 LdkrKKLFKALEKAGVVVECYPLKERELPAWIRQRLKAAGLRIDPDAAQLLAERVGGDLLALAQELEKLALYAgDGGTIT 183
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 237 KEVVEQLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILIndlinilkewiifnktrdqSLVSTDFKILLQ 316
Cdd:COG1466  184 LEDVEALVGDSAEFNVFDLADALLAGDAARALRILRRLLAEGEEPVLIL-------------------AALARQFRLLLQ 244

                 ....*..
gi 896405248 317 IKIDDAK 323
Cdd:COG1466  245 VKALLAQ 251
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
37-179 2.76e-08

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 53.44  E-value: 2.76e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  37 LNNKLSHAYLFCGPHGNGKTSTAKVFANTINC--LHNQSDILkpceeciknvdrnldiieIDAASNTGIDDIRELKEKIK 114
Cdd:cd19481   21 YGLGLPKGILLYGPPGTGKTLLAKALAGELGLplIVVKLSSL------------------LSKYVGESEKNLRKIFERAR 82
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896405248 115 hlptQSKYKIYIIDEVHMLSK------------AAFNALLKTIEDPP--SHIIFILATTDPQKIPETILsRVQRFNFKL 179
Cdd:cd19481   83 ----RLAPCILFIDEIDAIGRkrdssgesgelrRVLNQLLTELDGVNsrSKVLVIAATNRPDLLDPALL-RPGRFDEVI 156
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
103-224 9.45e-08

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 54.65  E-value: 9.45e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 103 IDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFKLMTI 182
Cdd:PRK07471 123 VDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARLLPTIRSRCRKLRLRPLAP 202
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 896405248 183 ETLVSQLKDifnkENIEYEDDAINVIAKLGNGSLRDSLSIAD 224
Cdd:PRK07471 203 EDVIDALAA----AGPDLPDDPRAALAALAEGSVGRALRLAG 240
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
45-180 8.00e-07

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 48.91  E-value: 8.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248    45 YLFCGPHGNGKTSTAKVFANTINCLHNQSdILKPCEE--CIKNVDRNLDIIEIDAASNTGIDDIRELKEKIKhlptQSKY 122
Cdd:smart00382   5 ILIVGPPGSGKTTLARALARELGPPGGGV-IYIDGEDilEEVLDQLLLIIVGGKKASGSGELRLRLALALAR----KLKP 79
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896405248   123 KIYIIDEVHMLSKAAFNALL--------KTIEDPPSHIIFILATTDPQKIPETILSRvqRFNFKLM 180
Cdd:smart00382  80 DVLILDEITSLLDAEQEALLllleelrlLLLLKSEKNLTVILTTNDEKDLGPALLRR--RFDRRIV 143
PRK04132 PRK04132
replication factor C small subunit; Provisional
13-64 2.81e-06

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 50.61  E-value: 2.81e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 896405248  13 KYRPKIFDDIKGQDHIVTTLKNIILNNKLSHaYLFCGPHGNGK--TSTAKVFAN 64
Cdd:PRK04132  12 KYRPQRLDDIVGQEHIVKRLKHYVKTGSMPH-LLFAGPPGVGKclTGDTKVIAN 64
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
183-242 1.77e-05

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 42.84  E-value: 1.77e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 183 ETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRDSLSIADHVAIYCANKVIKKEVVEQ 242
Cdd:cd18133    4 EQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDDGKISLDRVYQ 63
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
15-252 2.31e-04

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 43.97  E-value: 2.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  15 RPKIFDDIKGQDHIVTTLKNII-----LNNKLSHAyLFCGPHGNGKTSTAKVFANTINClhNqsdilkpceecIK----- 84
Cdd:PRK00080  20 RPKSLDEFIGQEKVKENLKIFIeaakkRGEALDHV-LLYGPPGLGKTTLANIIANEMGV--N-----------IRitsgp 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  85 NVDRNLDIIEIdaASNtgiddireLKEKikhlptqskyKIYIIDEVHMLSKAAFNALLKTIED----------PPSHII- 153
Cdd:PRK00080  86 ALEKPGDLAAI--LTN--------LEEG----------DVLFIDEIHRLSPVVEEILYPAMEDfrldimigkgPAARSIr 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 154 -----FIL--ATTDPQKIPETILSR---VQRFNFklMTIETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLRdslsIA 223
Cdd:PRK00080 146 ldlppFTLigATTRAGLLTSPLRDRfgiVQRLEF--YTVEELEKIVKRSARILGVEIDEEGALEIARRSRGTPR----IA 219
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 896405248 224 --------DHvAIYCANKVIKKEVVEQLFGIVNIDNK 252
Cdd:PRK00080 220 nrllrrvrDF-AQVKGDGVITKEIADKALDMLGVDEL 255
holA TIGR01128
DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) ...
133-319 2.46e-04

DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) subunits are distinct proteins encoded by separate genes. The delta prime subunit (holB) exhibits sequence homology to the tau and gamma subunits (dnaX), but the delta subunit (holA) does not demonstrate this same homology with dnaX. The delta, delta prime, gamma, chi and psi subunits form the gamma complex subassembly of DNA polymerase III holoenzyme, which couples ATP to assemble the ring-shaped beta subunit around DNA forming a DNA sliding clamp. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273455 [Multi-domain]  Cd Length: 302  Bit Score: 43.40  E-value: 2.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  133 LSKAAFNALLKTIEDPPSHIIFILATTDP------QKIPETILSRVQrFNFKLMTIETLVSQLKDIFNKENIEYEDDAIN 206
Cdd:TIGR01128  59 PGAKGLKALEEYLANPPPDTLLLIEAPKLdkrkklTKWLKALKNAEI-VECKTPKEQELPRWIQARLKKLGLRIDPDAVQ 137
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  207 VIAKLGNGSLRDSLSIADHVAIYCANKVIKKEVVEQLFGIVNIDNKIELLNYMSMHDINKTLNLARELFSQGIDINILIn 286
Cdd:TIGR01128 138 LLAELVEGNLLAIAQELEKLALYAPDGKITLEDVEEAVSDSARFNVFDLTDALLEGKAARALRILKGLLGEGEEPLILL- 216
                         170       180       190
                  ....*....|....*....|....*....|...
gi 896405248  287 dlinilkewiifnktrdqSLVSTDFKILLQIKI 319
Cdd:TIGR01128 217 ------------------ALLQRQLRLLLQLKR 231
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
125-178 2.68e-04

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 42.71  E-value: 2.68e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 896405248 125 YIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNFK 178
Cdd:PRK08485  58 IIVIAAPSYGIEAQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLIIEKRK 111
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
123-175 2.79e-04

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 43.28  E-value: 2.79e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 896405248 123 KIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRF 175
Cdd:PRK05818  90 KIYIIYGIEKLNKQSANSLLKLIEEPPKNTYGIFTTRNENNILNTILSRCVQY 142
AAA_22 pfam13401
AAA domain;
46-157 9.08e-04

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 39.63  E-value: 9.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248   46 LFCGPHGNGKTSTAKVFANTincLHNQSD----ILKPCEECIKNVDRNLdIIEIDAASNTGiDDIRELKEKI-KHLPTQS 120
Cdd:pfam13401   9 VLTGESGTGKTTLLRRLLEQ---LPEVRDsvvfVDLPSGTSPKDLLRAL-LRALGLPLSGR-LSKEELLAALqQLLLALA 83
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 896405248  121 KYKIYIIDEVHMLSKAAFNaLLKTIEDPPSHII-FILA 157
Cdd:pfam13401  84 VAVVLIIDEAQHLSLEALE-ELRDLLNLSSKLLqLILV 120
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
98-200 9.28e-04

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 41.75  E-value: 9.28e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248  98 ASNTGIDDIRELKEKIKHLPTQSKYKIYIIDEVHMLSKAAFNALLKTIEDPPSHIIFILATTDPQKIPETILSRVQRFNF 177
Cdd:PRK06581  66 AKNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRSRCFKINV 145
                         90       100
                 ....*....|....*....|....*..
gi 896405248 178 K---LMTIETLVSQ-LKDIFNKENIEY 200
Cdd:PRK06581 146 RssiLHAYNELYSQfIQPIADNKTLDF 172
TIP49 COG1224
DNA helicase TIP49, TBP-interacting protein [Transcription];
127-242 3.10e-03

DNA helicase TIP49, TBP-interacting protein [Transcription];


Pssm-ID: 440837 [Multi-domain]  Cd Length: 452  Bit Score: 40.34  E-value: 3.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896405248 127 IDEVHMLSKAAFNALLKTIEDPPSHIIfILAT---------TD---PQKIPETILSRvqrfnfkLMTIET---LVSQLKD 191
Cdd:COG1224  298 IDDAHMLDIEAFSFLTRAMESELAPII-ILATnrgitkirgTDiesPHGIPLDLLDR-------LLIIPTrpyTEDEIRE 369
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 896405248 192 IF----NKENIEYEDDAINVIAKLG-NGSLRDS---LSIADHVAIYCANKVIKKEVVEQ 242
Cdd:COG1224  370 IIkiraEEEDIELSDDALEELTKIGvERSLRYAvqlLEPAYIIAKRRGRSKVTVEDVEE 428
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
15-64 3.86e-03

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 38.64  E-value: 3.86e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 896405248   15 RPKIFDDIKGQDHIVTTLKNIILNNK-----LSHAyLFCGPHGNGKTSTAKVFAN 64
Cdd:pfam05496   2 RPRTLDEYIGQEKVKENLKIFIEAAKqrgeaLDHV-LLYGPPGLGKTTLANIIAN 55
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
183-217 9.59e-03

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 35.20  E-value: 9.59e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 896405248 183 ETLVSQLKDIFNKENIEYEDDAINVIAKLGNGSLR 217
Cdd:cd18140    4 EQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMR 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH