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Conserved domains on  [gi|896410632|ref|WP_049347243|]
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sigma-70 family RNA polymerase sigma factor [Rothia mucilaginosa]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SigH_actino super family cl31274
RNA polymerase sigma-70 factor, TIGR02947 family; This group of sigma factors are members of ...
6-196 7.19e-105

RNA polymerase sigma-70 factor, TIGR02947 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and (with the exception of a paralog in Thermobifida fusca YX) one-to-a-genome distribution, to represent a conserved family. This family is restricted to the Actinobacteria and each gene examined is followed by an anti-sigma factor in an apparent operon.


The actual alignment was detected with superfamily member TIGR02947:

Pssm-ID: 131992 [Multi-domain]  Cd Length: 193  Bit Score: 301.51  E-value: 7.19e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632    6 TAADTRELRERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKR 85
Cdd:TIGR02947   2 AEETKTQRAQRFERDALEYLDQLYGAALRMTRNPADAEDLVQEAYAKAFSSFHQFKPGTNLKAWLYRILTNTYINSYRKA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   86 QREPQQSQGETVEDWQLAQAGEHDAVGLRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPL 165
Cdd:TIGR02947  82 QRRPQQSDDDDIEDWQLAKAASHTSNGLRSAELEALDGLPDQDIKDALQGLPEEFRQAVYLADVEGFAYKEIAEIMGTPI 161
                         170       180       190
                  ....*....|....*....|....*....|.
gi 896410632  166 GTVMSRLHRGRRILREKLLDYARENGLRPST 196
Cdd:TIGR02947 162 GTVMSRLHRGRKQLRKQLVDVAGERGFGPRA 192
 
Name Accession Description Interval E-value
SigH_actino TIGR02947
RNA polymerase sigma-70 factor, TIGR02947 family; This group of sigma factors are members of ...
6-196 7.19e-105

RNA polymerase sigma-70 factor, TIGR02947 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and (with the exception of a paralog in Thermobifida fusca YX) one-to-a-genome distribution, to represent a conserved family. This family is restricted to the Actinobacteria and each gene examined is followed by an anti-sigma factor in an apparent operon.


Pssm-ID: 131992 [Multi-domain]  Cd Length: 193  Bit Score: 301.51  E-value: 7.19e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632    6 TAADTRELRERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKR 85
Cdd:TIGR02947   2 AEETKTQRAQRFERDALEYLDQLYGAALRMTRNPADAEDLVQEAYAKAFSSFHQFKPGTNLKAWLYRILTNTYINSYRKA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   86 QREPQQSQGETVEDWQLAQAGEHDAVGLRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPL 165
Cdd:TIGR02947  82 QRRPQQSDDDDIEDWQLAKAASHTSNGLRSAELEALDGLPDQDIKDALQGLPEEFRQAVYLADVEGFAYKEIAEIMGTPI 161
                         170       180       190
                  ....*....|....*....|....*....|.
gi 896410632  166 GTVMSRLHRGRRILREKLLDYARENGLRPST 196
Cdd:TIGR02947 162 GTVMSRLHRGRKQLRKQLVDVAGERGFGPRA 192
PRK09652 PRK09652
RNA polymerase sigma factor RpoE; Provisional
14-189 3.07e-72

RNA polymerase sigma factor RpoE; Provisional


Pssm-ID: 236608 [Multi-domain]  Cd Length: 182  Bit Score: 218.52  E-value: 3.07e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  14 RERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQ 93
Cdd:PRK09652   9 RAAFALLVRRYQPRVKRLLSRLTRDPADAEDLVQETFIKAYRALHSFRGGAAFYTWLYRIARNTAINYLRKQGRRPPASD 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  94 GET--VEDWQLAQAGEHDAvglrSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSR 171
Cdd:PRK09652  89 VDAeeAEDFDLADALRDIS----TPENELLSAELEQRVRAAIESLPEELRTAITLREIEGLSYEEIAEIMGCPIGTVRSR 164
                        170
                 ....*....|....*...
gi 896410632 172 LHRGRRILREKLLDYARE 189
Cdd:PRK09652 165 IFRAREALRAKLQPLLDE 182
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
14-189 4.47e-47

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 154.38  E-value: 4.47e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  14 RERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQqsq 93
Cdd:COG1595   16 EAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRGSFRAWLYRIARNLAIDHLRKRRRRRE--- 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  94 getvedwQLAQAGEHDAVGLRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLH 173
Cdd:COG1595   93 -------LLDELAEELPDEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVKSRLS 165
                        170
                 ....*....|....*.
gi 896410632 174 RGRRILREKLLDYARE 189
Cdd:COG1595  166 RARKKLREALEEEGAL 181
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
22-88 2.35e-15

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 68.38  E-value: 2.35e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896410632   22 MQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQF--TEGTNLKAWLYRILTNTYINLYRKRQRE 88
Cdd:pfam04542   3 ERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFdpERGVSFSTWLYTIIRNAIIDYLRKQRRT 71
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
126-180 3.08e-13

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 62.51  E-value: 3.08e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 896410632 126 NTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILR 180
Cdd:cd06171    1 RERLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
 
Name Accession Description Interval E-value
SigH_actino TIGR02947
RNA polymerase sigma-70 factor, TIGR02947 family; This group of sigma factors are members of ...
6-196 7.19e-105

RNA polymerase sigma-70 factor, TIGR02947 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and (with the exception of a paralog in Thermobifida fusca YX) one-to-a-genome distribution, to represent a conserved family. This family is restricted to the Actinobacteria and each gene examined is followed by an anti-sigma factor in an apparent operon.


Pssm-ID: 131992 [Multi-domain]  Cd Length: 193  Bit Score: 301.51  E-value: 7.19e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632    6 TAADTRELRERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKR 85
Cdd:TIGR02947   2 AEETKTQRAQRFERDALEYLDQLYGAALRMTRNPADAEDLVQEAYAKAFSSFHQFKPGTNLKAWLYRILTNTYINSYRKA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   86 QREPQQSQGETVEDWQLAQAGEHDAVGLRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPL 165
Cdd:TIGR02947  82 QRRPQQSDDDDIEDWQLAKAASHTSNGLRSAELEALDGLPDQDIKDALQGLPEEFRQAVYLADVEGFAYKEIAEIMGTPI 161
                         170       180       190
                  ....*....|....*....|....*....|.
gi 896410632  166 GTVMSRLHRGRRILREKLLDYARENGLRPST 196
Cdd:TIGR02947 162 GTVMSRLHRGRKQLRKQLVDVAGERGFGPRA 192
PRK09652 PRK09652
RNA polymerase sigma factor RpoE; Provisional
14-189 3.07e-72

RNA polymerase sigma factor RpoE; Provisional


Pssm-ID: 236608 [Multi-domain]  Cd Length: 182  Bit Score: 218.52  E-value: 3.07e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  14 RERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQ 93
Cdd:PRK09652   9 RAAFALLVRRYQPRVKRLLSRLTRDPADAEDLVQETFIKAYRALHSFRGGAAFYTWLYRIARNTAINYLRKQGRRPPASD 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  94 GET--VEDWQLAQAGEHDAvglrSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSR 171
Cdd:PRK09652  89 VDAeeAEDFDLADALRDIS----TPENELLSAELEQRVRAAIESLPEELRTAITLREIEGLSYEEIAEIMGCPIGTVRSR 164
                        170
                 ....*....|....*...
gi 896410632 172 LHRGRRILREKLLDYARE 189
Cdd:PRK09652 165 IFRAREALRAKLQPLLDE 182
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
14-189 4.47e-47

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 154.38  E-value: 4.47e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  14 RERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQqsq 93
Cdd:COG1595   16 EAAFEELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLWRKLDSFRGRGSFRAWLYRIARNLAIDHLRKRRRRRE--- 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  94 getvedwQLAQAGEHDAVGLRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLH 173
Cdd:COG1595   93 -------LLDELAEELPDEAADPEEALEAEELLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVKSRLS 165
                        170
                 ....*....|....*.
gi 896410632 174 RGRRILREKLLDYARE 189
Cdd:COG1595  166 RARKKLREALEEEGAL 181
PRK11924 PRK11924
RNA polymerase sigma factor; Provisional
6-185 6.91e-39

RNA polymerase sigma factor; Provisional


Pssm-ID: 183384 [Multi-domain]  Cd Length: 179  Bit Score: 133.17  E-value: 6.91e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   6 TAADTRELRERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKR 85
Cdd:PRK11924   4 MPVDATGDKEAFSELFRPHAPDLLRYARRQLGDRALAEDAVQEAFLRAWRKADLFNGKGSARTWLLTIARNVCYDLLRRR 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  86 QREPqqsQGETVEDWQLAQAGEHDAVglrsaEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPL 165
Cdd:PRK11924  84 RREK---AVLSDDALEPEFAETAETP-----EAALLAKDDLARIDRCLDALPVKQREVFLLRYVEGLSYREIAEILGVPV 155
                        170       180
                 ....*....|....*....|
gi 896410632 166 GTVMSRLHRGRRILREKLLD 185
Cdd:PRK11924 156 GTVKSRLRRARQLLRECLEA 175
PRK09647 PRK09647
RNA polymerase sigma factor SigE; Reviewed
23-195 3.59e-33

RNA polymerase sigma factor SigE; Reviewed


Pssm-ID: 236606 [Multi-domain]  Cd Length: 203  Bit Score: 119.12  E-value: 3.59e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  23 QYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTnLKAWLYRILTNTYINLYRKRQREPQQSQGEtvedwql 102
Cdd:PRK09647  36 QHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSLQNYQPGT-FEGWLHRITTNLFLDMVRRRARIRMEALPE------- 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 103 aqagEHDAVGLRSAEVEALSALPN--TEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILR 180
Cdd:PRK09647 108 ----DYDRVPGDEPNPEQIYHDARldPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIAATLGVKLGTVRSRIHRGRQQLR 183
                        170
                 ....*....|....*
gi 896410632 181 EKLLDYARENGLRPS 195
Cdd:PRK09647 184 AALAAHAPHAECAAL 198
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
15-183 4.19e-33

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 117.45  E-value: 4.19e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   15 ERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPqqsqg 94
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPEGSFKAWLFRIARNLILDYLRRKRRLR----- 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   95 etVEDWQLAQAGEHDAvglrSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHR 174
Cdd:TIGR02937  76 --RELDLLEELLDSDP----SPEEELEQEEEREALREALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKR 149

                  ....*....
gi 896410632  175 GRRILREKL 183
Cdd:TIGR02937 150 ARKKLRELL 158
PRK12546 PRK12546
RNA polymerase sigma factor; Provisional
28-183 6.35e-31

RNA polymerase sigma factor; Provisional


Pssm-ID: 139055 [Multi-domain]  Cd Length: 188  Bit Score: 113.01  E-value: 6.35e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  28 LYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVEdwQLAQAGE 107
Cdd:PRK12546  20 LRAFAISLTRNVAVADDLVQDTIVKAWTNFDKFQEGTNLRAWLFTILRNTFYSDRRKHKREVPDPEGVHAA--SLAVKPA 97
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896410632 108 HDAvglrsaevealsALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:PRK12546  98 HDG------------RLAMSDFRAAFAQLPDEQREALILVGASGFSYEEAAEMCGVAVGTVKSRANRARARLAELL 161
PRK09641 PRK09641
RNA polymerase sigma factor SigW; Provisional
24-183 1.79e-29

RNA polymerase sigma factor SigW; Provisional


Pssm-ID: 182012 [Multi-domain]  Cd Length: 187  Bit Score: 109.02  E-value: 1.79e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  24 YVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKR------QREPQQSQGETV 97
Cdd:PRK09641  27 YKDKIYQLCYRMLGNRHEAEDAAQEAFIRAYVNIDSYDINRKFSTWLYRIATNLTIDRLRKRkpdyylDAEVAGTEGLTM 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  98 EDwQLAQAGehdavglRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRR 177
Cdd:PRK09641 107 YS-QLAADD-------ALPEEQVVSLELQETIQEAILQLPEKYRTVIVLKYIEDLSLKEISEILDLPVGTVKTRIHRGRE 178

                 ....*.
gi 896410632 178 ILREKL 183
Cdd:PRK09641 179 ALRKQL 184
PRK12522 PRK12522
RNA polymerase sigma factor; Provisional
24-183 1.26e-28

RNA polymerase sigma factor; Provisional


Pssm-ID: 183571 [Multi-domain]  Cd Length: 173  Bit Score: 106.49  E-value: 1.26e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  24 YVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREP-------QQSQGET 96
Cdd:PRK12522  12 YKQQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWITTICVRTFYDFYRKKKRWKdrildlfHKEDGGE 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  97 VEdwqlaqagEHDAVGLRSAEVEALSAlpnTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGR 176
Cdd:PRK12522  92 IE--------FADDVNISEEFIQKVEA---EMIREVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAK 160

                 ....*..
gi 896410632 177 RILREKL 183
Cdd:PRK12522 161 KQMREHL 167
PRK09638 PRK09638
RNA polymerase sigma factor SigY; Reviewed
23-183 9.80e-28

RNA polymerase sigma factor SigY; Reviewed


Pssm-ID: 182010 [Multi-domain]  Cd Length: 176  Bit Score: 104.33  E-value: 9.80e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  23 QYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGET-----V 97
Cdd:PRK09638  26 QHYSFLYKYLLKLTLDPDLAEDLVQETMLKAIENLSSFQGRSKFSTWLISIASRLYKDHLRKQKREKLRLQRAKeetlrK 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  98 EDWQLAQAGEHdavglrsaevealsalpNTEVREALNELSEDFRMVV----YYsdveGFAYKDIAEILDIPLGTVMSRLH 173
Cdd:PRK09638 106 EKWEAAIKGAE-----------------WSEMLDALSKLDPEFRAPVilkhYY----GYTYEEIAKMLNIPEGTVKSRVH 164
                        170
                 ....*....|
gi 896410632 174 RGRRILREKL 183
Cdd:PRK09638 165 HGIKQLRKEW 174
PRK12547 PRK12547
RNA polymerase sigma factor; Provisional
17-183 1.61e-27

RNA polymerase sigma factor; Provisional


Pssm-ID: 139056 [Multi-domain]  Cd Length: 164  Bit Score: 103.42  E-value: 1.61e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  17 FTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGET 96
Cdd:PRK12547   8 FKQELLLALPALRAFAVSLSSKHDKAEDLVQDTLMKAWAKQDSFEMGTNLKAWLFTILRNEFYSQMRKRGREVQDSDGVF 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  97 VEDWQLAQAgEHDAVGLRsaevealsalpntEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGR 176
Cdd:PRK12547  88 TARVAVHPA-QYGSLDLQ-------------DFKKALNLLSADQREAIILIGASGFSYEDAAAICGCAVGTIKSRVSRAR 153

                 ....*..
gi 896410632 177 RILREKL 183
Cdd:PRK12547 154 NRLQELL 160
PRK12511 PRK12511
RNA polymerase sigma factor; Provisional
29-194 8.09e-26

RNA polymerase sigma factor; Provisional


Pssm-ID: 237123 [Multi-domain]  Cd Length: 182  Bit Score: 99.47  E-value: 8.09e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  29 YAAALrmSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVEDWQLAQAGEH 108
Cdd:PRK12511  20 YARSL--TRDSAEAEDLVHDALVRALERRASFRSGGNLRTWLMSILHNAFIDELRRRRVEARRADELAVLADASLPAAQE 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 109 DAVGLrsaevealsalpnTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILReklldyAR 188
Cdd:PRK12511  98 HAVRL-------------AQIRDAFFDLPEEQRAALHLVAIEGLSYQEAAAVLGIPIGTLMSRIGRARAALR------AF 158

                 ....*.
gi 896410632 189 ENGLRP 194
Cdd:PRK12511 159 EEGTGP 164
PRK09637 PRK09637
RNA polymerase sigma factor SigZ; Provisional
27-185 1.41e-25

RNA polymerase sigma factor SigZ; Provisional


Pssm-ID: 236601 [Multi-domain]  Cd Length: 181  Bit Score: 98.90  E-value: 1.41e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  27 QLYAAALR---MSR--NSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREpqqsqgETVEDWQ 101
Cdd:PRK09637   8 SEYKAQLKaflHSRvsNEADVDDLLQEVLIKTHSNLHSLKDGSSIKSWLYQIANNTIIDFYRKKNRS------EELPDDL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 102 LAQAGEHDavglRSAEVEALSALPNTevreaLNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILRE 181
Cdd:PRK09637  82 LFEDEERE----ENAKKELAPCLRPF-----IDALPEKYAEALRLTELEGLSQKEIAEKLGLSLSGAKSRVQRGRVKLKE 152

                 ....
gi 896410632 182 KLLD 185
Cdd:PRK09637 153 LLEG 156
PRK12533 PRK12533
RNA polymerase sigma factor; Provisional
14-179 2.98e-25

RNA polymerase sigma factor; Provisional


Pssm-ID: 237129 [Multi-domain]  Cd Length: 216  Bit Score: 99.03  E-value: 2.98e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  14 RERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFtEGTNLKAWLYRILTNTYINLYRKRQREPQQS- 92
Cdd:PRK12533  17 GERFRQLVLPHLDAAYNLARWLCGNASDADDVVQEACMRALRFFDSF-RGDNARPWLLAIVRHTWYSEWRRRANAHEVAa 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  93 -----QGETVEDWQLAqAGEHDAVGLRSAEVEAlsalpnteVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGT 167
Cdd:PRK12533  96 pdtldDADSLDDWQPA-GEDPLALLLRAEDVRL--------VNAALAKLPVEYREVLVLRELEDMSYREIAAIADVPVGT 166
                        170
                 ....*....|..
gi 896410632 168 VMSRLHRGRRIL 179
Cdd:PRK12533 167 VMSRLARARRRL 178
SigM_subfam TIGR02950
RNA polymerase sigma factor, SigM family; This family of RNA polymerase sigma factors is a ...
23-183 6.79e-25

RNA polymerase sigma factor, SigM family; This family of RNA polymerase sigma factors is a member of the Sigma-70 subfamily (TIGR02937) and is restricted to certain lineages of the order Bacillales. This family encompasses at least two distinct sigma factors as two proteins are found in each of B. anthracis, B. subtilis subsp. subtilis str. 168, and B. lichiniformis (although these are not apparently the same two in each). One of these is designated as SigM in B. subtilis (Swiss_Prot:


Pssm-ID: 274361 [Multi-domain]  Cd Length: 154  Bit Score: 96.37  E-value: 6.79e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   23 QYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFtEGTNLKAWLYRILTNTYINLYRKRQREpqqsqgETVEDWQL 102
Cdd:TIGR02950   3 EYMHDVFRYLYRLTKDKHLAEDLLQETFLKAYIHLHSF-KDSSIKPWLFRIARNAFIDWYRKDKKI------QTIDDDAI 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  103 AQAgEHDAVGlrSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREK 182
Cdd:TIGR02950  76 GDL-EQHPVE--SPEHHLLIKIEQEEITHHLSRLPENYRTVLILREFKEFSYKEIAELLNLSLAKVKSNLFRARKELKKL 152

                  .
gi 896410632  183 L 183
Cdd:TIGR02950 153 L 153
PRK12516 PRK12516
RNA polymerase sigma factor; Provisional
6-183 2.64e-24

RNA polymerase sigma factor; Provisional


Pssm-ID: 183568 [Multi-domain]  Cd Length: 187  Bit Score: 95.80  E-value: 2.64e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   6 TAADTRELRERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKR 85
Cdd:PRK12516   1 TTGPSVEGTPPFKRELLAALPSLRAFAVSLIGRHDRADDLVQDTIMKAWAKQDHFEVGTNMKAWLFTILRNEFYSQMRKR 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  86 QREPQQSQGETVEdwQLAqagehdavglrsAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPL 165
Cdd:PRK12516  81 GREVQDTDGMFTE--QLA------------VHPSQYGTLDLQDFRAALDQLPDDQREAIILVGASGFAYEEAAEICGCAV 146
                        170
                 ....*....|....*...
gi 896410632 166 GTVMSRLHRGRRILREKL 183
Cdd:PRK12516 147 GTIKSRVNRARQRLQEIL 164
SigZ TIGR02959
RNA polymerase sigma factor, SigZ family; This family of RNA polymerase sigma factors is a ...
23-185 1.88e-23

RNA polymerase sigma factor, SigZ family; This family of RNA polymerase sigma factors is a member of the Sigma-70 subfamily (TIGR02937). One of these is designated as SigZ in B. subtilis (Swiss_Prot: SIGZ_BACSU). Interestingly, this group has a very sporatic distribution, B. subtilis, for instance, being the only sequenced strain of Bacilli with a member. Dechloromonas aromatica RCB appears to have two of these sigma factors. A member appears on a plasmid found in Photobacterium profundum SS9 and Vibrio fischeri ES114 (where a second one is chromosomally encoded).


Pssm-ID: 132004 [Multi-domain]  Cd Length: 170  Bit Score: 92.81  E-value: 1.88e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   23 QYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREpqqsqgETVEDWQL 102
Cdd:TIGR02959   3 EFRSELKAFIKSRVSDASDVEDLLQEVFIKIHRNLPSLKDGQKIQSWLYQIARNTIIDFYRSKSRS------VELPESLL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  103 AQAGEHDavglRSAEVEALSALPNTevreaLNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREK 182
Cdd:TIGR02959  77 AADSARE----ETFVKELSQCIPPM-----IKELPDEYREAIRLTELEGLSQQEIAEKLGLSLSGAKSRVQRGRKKLKEL 147

                  ...
gi 896410632  183 LLD 185
Cdd:TIGR02959 148 LET 150
PRK12540 PRK12540
RNA polymerase sigma factor; Provisional
10-183 4.44e-23

RNA polymerase sigma factor; Provisional


Pssm-ID: 183579 [Multi-domain]  Cd Length: 182  Bit Score: 92.33  E-value: 4.44e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  10 TRELRErftaDAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREP 89
Cdd:PRK12540   4 TDSLRD----DILAAVPSLRAFAISLSGNGDRADDLVQETLLRALANIDSFQPGSNLPAWLFTILRNLFRSDYRKRRREV 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  90 QQSQGETvedwqlaqagehdAVGLRSAEVEAlSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVM 169
Cdd:PRK12540  80 EDADGSY-------------AKTLKSQPGQN-AHLEFEEFRAALDKLPQDQREALILVGASGFSYEDAAAICGCAVGTIK 145
                        170
                 ....*....|....
gi 896410632 170 SRLHRGRRILREKL 183
Cdd:PRK12540 146 SRVNRARSKLSALL 159
PRK11922 PRK11922
RNA polymerase sigma factor; Provisional
28-183 7.22e-23

RNA polymerase sigma factor; Provisional


Pssm-ID: 237024 [Multi-domain]  Cd Length: 231  Bit Score: 93.11  E-value: 7.22e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  28 LYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNtyINLYRKRQREPQQSQGETVEDwqlAQAGE 107
Cdd:PRK11922  43 LYRTARAILRNDAEAEDVVQEAYLRAFRALGTFRGDASLSTWLSRIVLN--EALGRLRRRRRLVNLAEMVMA---STIAG 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 108 HDAVGLRSAEVEALSALPNTEVRE----ALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:PRK11922 118 GERTPLADPAEDPERAAARREIRAllerAIDALPDAFRAVFVLRVVEELSVEETAQALGLPEETVKTRLHRARRLLRESL 197
PRK12518 PRK12518
RNA polymerase sigma factor; Provisional
43-183 2.16e-21

RNA polymerase sigma factor; Provisional


Pssm-ID: 237124 [Multi-domain]  Cd Length: 175  Bit Score: 87.47  E-value: 2.16e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  43 EDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVEDWQLAQAGEHDavgLRSAEVEALs 122
Cdd:PRK12518  38 DDLVQEVFLRVWKGLPKLRNPAYFSTWLYRITWNVATDARRQFAQRPSRIQDDSLNDQPSRPSDTPD---LMQLHYQDL- 113
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896410632 123 alpnteVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:PRK12518 114 ------VQQGLQTLSLEHRAVLVLHDLEDLPQKEIAEILNIPVGTVKSRLFYARRQLRKFL 168
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
15-183 2.23e-21

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 87.23  E-value: 2.23e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   15 ERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREpQQSQG 94
Cdd:TIGR02985   1 EAFEQLYRRYYPKLCAFARRYVKDEEDAEDIVQDVFLKLWENRETLEISESIKAYLFTIVKNRCLNYLRHKQVE-EKYQE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   95 ETVEdwqLAQAGEHDAVGLRSAEVEALsalpNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHR 174
Cdd:TIGR02985  80 ELAE---IEERELSEADPEEELEAKEL----EEIIEEAIEKLPEQCREIFILSRFEGLSNKEIAEELGISVKTVEYHITK 152

                  ....*....
gi 896410632  175 GRRILREKL 183
Cdd:TIGR02985 153 ALKFLRKEL 161
algU PRK11923
RNA polymerase sigma factor AlgU; Provisional
22-176 8.77e-20

RNA polymerase sigma factor AlgU; Provisional


Pssm-ID: 171347 [Multi-domain]  Cd Length: 193  Bit Score: 83.70  E-value: 8.77e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  22 MQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGEtVEDWQ 101
Cdd:PRK11923  27 LKYQHKILGLIVRFVHDTAEAQDVAQEAFIKAYRALGNFRGDSAFYTWLYRIAINTAKNHLVSRGRRPPDSDVS-SEDAE 105
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896410632 102 LAQaGEHDAVGLRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGR 176
Cdd:PRK11923 106 FYD-GDHALKDIESPERALLRDEIEGTVHRTIQQLPEDLRTALTLREFDGLSYEDIASVMQCPVGTVRSRIFRAR 179
PRK09645 PRK09645
ECF RNA polymerase sigma factor SigL;
3-188 1.63e-19

ECF RNA polymerase sigma factor SigL;


Pssm-ID: 236605 [Multi-domain]  Cd Length: 173  Bit Score: 82.43  E-value: 1.63e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   3 GTNTAADTRELRERFTADAmqyvDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFT-EGTNLKAWLYRILTNTYINL 81
Cdd:PRK09645   1 SGMATAEAALMRALYDEHA----APLWRYALRLTGDRARAEDVVQETLLRAWQHPEVLAdTGRSARAWLFTVARNLVIDE 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  82 YRKRQREPQQSQGETvedwqlaqagehDAVGLRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEIL 161
Cdd:PRK09645  77 RRSARARPVEGGDDV------------LGVPEQSAPDEVDRALDRLLVADALAQLSPEHRAVLVRSYYRGWSTAQIAADL 144
                        170       180
                 ....*....|....*....|....*..
gi 896410632 162 DIPLGTVMSRLHRGRRILREKLLDYAR 188
Cdd:PRK09645 145 GIPEGTVKSRLHYALRALRLALQERGV 171
PRK09639 PRK09639
RNA polymerase sigma factor SigX; Provisional
23-181 5.84e-19

RNA polymerase sigma factor SigX; Provisional


Pssm-ID: 236602 [Multi-domain]  Cd Length: 166  Bit Score: 80.76  E-value: 5.84e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  23 QYVDQLYAAALRMSRNSADAEDLVQETYMKAFASyhQFTEGTNLKAWLYRILTNTYINLYRKRQRepQQSQGETVEDW-Q 101
Cdd:PRK09639  11 QYYPDVVQQIFYIVKDRTQAEDLAQEVFLRLYRS--DFKGIENEKGWLIKSARNVAYNYLRSEKR--RRARILGEFQWqE 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 102 LAQAGEHDAVGLRSAEVealsalpnTEVREALNELSEDFRMVVY--YSdveGFAYKDIAEILDIPLGTVMSRLHRGRRIL 179
Cdd:PRK09639  87 VDNEPSPEEIWIRKEEI--------TKVQEVLAKMTERDRTVLLlrFS---GYSYKEIAEALGIKESSVGTTLARAKKKF 155

                 ..
gi 896410632 180 RE 181
Cdd:PRK09639 156 RK 157
PRK09643 PRK09643
RNA polymerase sigma factor SigM; Reviewed
26-191 2.02e-18

RNA polymerase sigma factor SigM; Reviewed


Pssm-ID: 236604 [Multi-domain]  Cd Length: 192  Bit Score: 80.14  E-value: 2.02e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  26 DQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVEDWQLAQA 105
Cdd:PRK09643  38 RRLWAVARRTSGTREDAADALQDAMLSAHRAAGSFRGDAAVSSWLHRIVVNACLDRLRRAKARPTVPLDDVYPVAQLERD 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 106 gehdavglRSAEVEALsalpnTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREkLLD 185
Cdd:PRK09643 118 --------PTARVETA-----LAVQRALMRLPVEQRAALVAVDMQGYSVADAARMLGVAEGTVKSRCARGRARLAE-LLG 183

                 ....*.
gi 896410632 186 YARENG 191
Cdd:PRK09643 184 YLRAGG 189
PRK12538 PRK12538
RNA polymerase sigma factor; Provisional
4-189 3.04e-17

RNA polymerase sigma factor; Provisional


Pssm-ID: 139048 [Multi-domain]  Cd Length: 233  Bit Score: 77.97  E-value: 3.04e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   4 TNTAADTRELRERftadamqYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEG-TNLKAWLYRILTNTYINLY 82
Cdd:PRK12538  59 TDDEAAFRLLVER-------HIDRAYAIALRIVGNRADAEDVVQDTMLKVWTHRGRWQHGrAKFSTWLYRVVSNRCIDLR 131
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  83 RKrqrePQQSQGETVEDwqlAQAGEHDAVglRSAEVEALSALpnteVREALNELSEDFRMVVYYSDVEGFAYKDIAEILD 162
Cdd:PRK12538 132 RK----PRTENVDAVPE---VADGKPDAV--SVIERNELSDL----LEAAMQRLPEQQRIAVILSYHENMSNGEIAEVMD 198
                        170       180
                 ....*....|....*....|....*..
gi 896410632 163 IPLGTVMSRLHRGRRILREKLLDYARE 189
Cdd:PRK12538 199 TTVAAVESLLKRGRQQLRDLLRRHERD 225
SigE-fam_strep TIGR02983
RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors ...
14-183 4.44e-17

RNA polymerase sigma-70 factor, sigma-E family; This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.


Pssm-ID: 132028 [Multi-domain]  Cd Length: 162  Bit Score: 75.89  E-value: 4.44e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   14 RERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREpqqsq 93
Cdd:TIGR02983   5 EEEFTAFVAARYPRLLRTAYLLTGDPHEAEDLVQEALVRTYVRWDRIRDPDAPDAYVRRVLVNLARSRWRRRRLL----- 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   94 getvedwQLAQAGEHDAVGLRSAEVEALSAlpntEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLH 173
Cdd:TIGR02983  80 -------ELPTRELPDAAAPDPAPDVALRA----ALARALRRLPARQRAVVVLRYYEDLSEAQVAEALGISVGTVKSRLS 148
                         170
                  ....*....|
gi 896410632  174 RGRRILREKL 183
Cdd:TIGR02983 149 RALARLRELL 158
PRK08241 PRK08241
RNA polymerase subunit sigma-70;
1-181 4.57e-17

RNA polymerase subunit sigma-70;


Pssm-ID: 236196 [Multi-domain]  Cd Length: 339  Bit Score: 78.83  E-value: 4.57e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   1 MAGTNTAADTRELRERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYIN 80
Cdd:PRK08241   5 AAAALLARAAAGDRDAFAALVEPHRRELLAHCYRMLGSVHDAEDAVQETLLRAWRGYDRFEGRSSLRTWLYRIATNVCLD 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  81 LYRKRQREPQQSqGETVEDWQLAQAGE--HDAVGLR---SAEVEALSALPN--TEVRE--------ALNELSEDFRMVVY 145
Cdd:PRK08241  85 ALEGRARRPLPT-DLGAPAADPVDELVerPEVPWLEpypDALLDPAAADPAarVVAREsvrlafvaALQHLPPRQRAVLI 163
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 896410632 146 YSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILRE 181
Cdd:PRK08241 164 LRDVLGWSAAEVAELLDTSVAAVNSALQRARATLAE 199
PRK12519 PRK12519
RNA polymerase sigma factor; Provisional
29-186 6.43e-17

RNA polymerase sigma factor; Provisional


Pssm-ID: 237125 [Multi-domain]  Cd Length: 194  Bit Score: 76.25  E-value: 6.43e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  29 YAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYrILTNTYInLYRKRQRepqQSQGETVEDWQLAQAGEH 108
Cdd:PRK12519  43 YGLALKILGNSQEAEDLTQEIFLSLWRKSSYDPKRGSLSSYLL-TLTRSRA-IDRLRSR---RSRQRLLERWQQELLGEA 117
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896410632 109 DAVG-LRSAEVEALSAlpntEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKLLDY 186
Cdd:PRK12519 118 SEDTpLEQASLAERSQ----RVQTALAQLPESQRQVLELAYYEGLSQSEIAKRLGIPLGTVKARARQGLLKLRELLQDL 192
PRK12541 PRK12541
RNA polymerase sigma factor; Provisional
23-180 8.26e-17

RNA polymerase sigma factor; Provisional


Pssm-ID: 183580 [Multi-domain]  Cd Length: 161  Bit Score: 74.97  E-value: 8.26e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  23 QYVDQLYAAALRMSRNSADAEDLVQETYMKAFAsYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQsqgeTVEDWQL 102
Cdd:PRK12541  13 EHMQDLFRYLLSLTGDSHFAEDLMQETFYRMLV-HIDYYKGEEIRPWLFTIAYNAFIDWYRKEKKYKTT----TIEEFHL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 103 AQAGEHDAVGLRSAEV----EALSALPNTEvrealnelsedfRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRI 178
Cdd:PRK12541  88 PNVPSTEHEYFIKHEIaswlDSLSSLPLER------------RNVLLLRDYYGFSYKEIAEMTGLSLAKVKIELHRGRKE 155

                 ..
gi 896410632 179 LR 180
Cdd:PRK12541 156 TK 157
PRK12543 PRK12543
RNA polymerase sigma factor; Provisional
28-182 9.03e-16

RNA polymerase sigma factor; Provisional


Pssm-ID: 183582 [Multi-domain]  Cd Length: 179  Bit Score: 72.84  E-value: 9.03e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  28 LYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQR-----EPQQSQGETVEDWQl 102
Cdd:PRK12543  20 VYKTVHFLVEDKQDVDDVVNEIYIQLWESLRKYDSNRPFRFWLIGLVIKQIHSWRRKRWRrfrifEKAEEQRKPVSIDF- 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 103 aqagehdavglrsaEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREK 182
Cdd:PRK12543  99 --------------SEDVLSKESNQELIELIHKLPYKLRQVIILRYLHDYSQEEIAQLLQIPIGTVKSRIHAALKKLRQK 164
PRK09644 PRK09644
RNA polymerase sigma factor SigM; Provisional
24-181 9.59e-16

RNA polymerase sigma factor SigM; Provisional


Pssm-ID: 170033 [Multi-domain]  Cd Length: 165  Bit Score: 72.22  E-value: 9.59e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  24 YVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFtEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETveDWQLA 103
Cdd:PRK09644  10 YINDVYRYLFSLTKSHHAAEDLLQETFYRAYIYLEDY-DNQKVKPWLFKVAYHTFIDFVRKEKKVSFVGTDEI--EAIQA 86
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896410632 104 QAGEHDAVGLRSAEVealsalpnteVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILRE 181
Cdd:PRK09644  87 ESTEEYVVAKNSYEK----------LIQIIHTLPVIEAQAILLCDVHELTYEEAASVLDLKLNTYKSHLFRGRKRLKA 154
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
22-88 2.35e-15

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 68.38  E-value: 2.35e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896410632   22 MQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQF--TEGTNLKAWLYRILTNTYINLYRKRQRE 88
Cdd:pfam04542   3 ERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFdpERGVSFSTWLYTIIRNAIIDYLRKQRRT 71
PRK09415 PRK09415
RNA polymerase factor sigma C; Reviewed
37-183 4.34e-15

RNA polymerase factor sigma C; Reviewed


Pssm-ID: 181835 [Multi-domain]  Cd Length: 179  Bit Score: 70.93  E-value: 4.34e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  37 RNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNT---------YINLYRKRQREPQ-QSQGETVEDWQLAQAG 106
Cdd:PRK09415  38 KNKEVAEDLTQEIFVKCYKSLHTYKGKSSLKTWLYRIAINHckdylkswhNKKVIVTEDIFTYmESQKESVEEEVIQNAE 117
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 896410632 107 EHdavglrsaevealsalpntEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:PRK09415 118 DE-------------------RLASAVMSLPIKYREVIYLFYYEELSIKEIAEVTGVNENTVKTRLKKAKELLKKGL 175
SigX5 TIGR02960
RNA polymerase sigma-70 factor, TIGR02960 family; This group of sigma factors are members of ...
17-183 6.14e-15

RNA polymerase sigma-70 factor, TIGR02960 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and one-to-a-genome distribution, to represent a conserved family.


Pssm-ID: 132005 [Multi-domain]  Cd Length: 324  Bit Score: 72.97  E-value: 6.14e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   17 FTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSqgET 96
Cdd:TIGR02960   7 FTALAEPHRRELLAHCYRMLGSLHEAEDLVQETLLRAWRARDRFEGRSSVRTWLYRIATNACLDALEARQRRPRPV--GL 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   97 VEDWQLAQAgehdAVGLRsAEVEALSALPNTEV----------------RE--------ALNELSEDFRMVVYYSDVEGF 152
Cdd:TIGR02960  85 GAPSADGTA----AASEA-AEVTWLEPLPDLTLdlddpaaadpsvaagsREsvrlafvaAIQYLPPRQRAVLLLRDVLGW 159
                         170       180       190
                  ....*....|....*....|....*....|.
gi 896410632  153 AYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:TIGR02960 160 RAAETAELLGTSTASVNSALQRARATLDEVG 190
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
126-180 3.08e-13

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 62.51  E-value: 3.08e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 896410632 126 NTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILR 180
Cdd:cd06171    1 RERLEEALDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
Sigma70_r4_2 pfam08281
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
128-179 1.54e-12

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.


Pssm-ID: 400535 [Multi-domain]  Cd Length: 54  Bit Score: 60.55  E-value: 1.54e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 896410632  128 EVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRIL 179
Cdd:pfam08281   3 ALLRALEELPPRQREVFLLRYLEGLSYAEIAELLGISEGTVKSRLSRARKKL 54
PRK05602 PRK05602
RNA polymerase sigma factor; Reviewed
3-185 2.00e-12

RNA polymerase sigma factor; Reviewed


Pssm-ID: 235530 [Multi-domain]  Cd Length: 186  Bit Score: 63.90  E-value: 2.00e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   3 GTNTAADTRELRERftadamqYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEG-TNLKAWLYRILTNTYINL 81
Cdd:PRK05602  15 AAGDPAAFRVLVAR-------KLPRLLALATRMLGDPAEAEDVAQETFLRIWKQAPSWRPGeARFDTWLHRVVLNLCYDR 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  82 YRKRQREPQQSQGETVEDWQLAQAGEHDAVglRSAEVE-ALSALPNTEvREALnelsedfrMVVYYsdvEGFAYKDIAEI 160
Cdd:PRK05602  88 LRRRREVPVEDAPDVPDPAPGPDAGLEARQ--RARRVEqALAALPERQ-REAI--------VLQYY---QGLSNIEAAAV 153
                        170       180
                 ....*....|....*....|....*
gi 896410632 161 LDIPLGTVMSRLHRGRRILREKLLD 185
Cdd:PRK05602 154 MDISVDALESLLARGRRALRAQLAD 178
PRK12513 PRK12513
RNA polymerase sigma factor; Provisional
28-183 2.44e-12

RNA polymerase sigma factor; Provisional


Pssm-ID: 183566 [Multi-domain]  Cd Length: 194  Bit Score: 63.55  E-value: 2.44e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  28 LYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRK--RQREPQQSQGETVEdwqlAQA 105
Cdd:PRK12513  39 LYRFLLRLARDRALAEDIFQETWLRVIRARAQYQPRARFRTWLYQIARNLLIDHWRRhgARQAPSLDADEQLH----ALA 114
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896410632 106 GEHDAVglrsaEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:PRK12513 115 DDGAAP-----EQQLSLFRDRRRLQAALETLPDEQREVFLLREHGDLELEEIAELTGVPEETVKSRLRYALQKLRELL 187
PRK09640 PRK09640
RNA polymerase sigma factor SigX; Reviewed
2-187 3.13e-12

RNA polymerase sigma factor SigX; Reviewed


Pssm-ID: 236603 [Multi-domain]  Cd Length: 188  Bit Score: 63.42  E-value: 3.13e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   2 AGTNTAADTRELRERFTadamQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINL 81
Cdd:PRK09640  17 VHVELFHVTRAYEELMR----RYQRTLFNVCARYLGNDRDADDVCQEVMLKVLYGLKNFEGKSKFKTWLYSITYNECITQ 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  82 YRKRQREPQQSQGETVEDwqlAQAGEHDavglRSAEVEALSALPNTEVReaLNELSEDFRMVVYYSDVEgfaYKDIAEIL 161
Cdd:PRK09640  93 YRKERRKRRLMDALSLDP---LEEASEE----KAPKPEERGGLDRWLVH--VNPIDREILVLRFVAELE---FQEIADIM 160
                        170       180
                 ....*....|....*....|....*.
gi 896410632 162 DIPLGTVMSRLHRGRRILREKLLDYA 187
Cdd:PRK09640 161 HMGLSATKMRYKRALDKLREKFAGLA 186
PRK12514 PRK12514
RNA polymerase sigma factor; Provisional
27-183 4.63e-12

RNA polymerase sigma factor; Provisional


Pssm-ID: 105710 [Multi-domain]  Cd Length: 179  Bit Score: 62.53  E-value: 4.63e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  27 QLYAAALRMSRNSADAEDLVQETYMKAFASYHQF-TEGTNLKAWLYRILTNTYINLYRKRQRepqqsqgeTVEDWQLAqa 105
Cdd:PRK12514  31 KLFGICLRVLKDRSEAEEALQDVYVKIWTKADRFaVSGLSPMTWLITIARNHAIDRLRARKA--------VAVDIDEA-- 100
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896410632 106 geHDAV-GLRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:PRK12514 101 --HDLAdPSPGPEAEVIAGDEGQRIDACLEELEKDRAAAVRRAYLEGLSYKELAERHDVPLNTMRTWLRRSLLKLRECL 177
PRK13919 PRK13919
putative RNA polymerase sigma E protein; Provisional
23-185 9.87e-11

putative RNA polymerase sigma E protein; Provisional


Pssm-ID: 184395 [Multi-domain]  Cd Length: 186  Bit Score: 59.16  E-value: 9.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  23 QYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFT-EGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVEDwq 101
Cdd:PRK13919  31 RYAGAFLALARRMGLDGAAAEDVVQEVFIRVWKKAKEFDpRRGSARAWLLALAHHAAVDHVRRRAARPQPLEPDEREP-- 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 102 laqagehDAVGLRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILRE 181
Cdd:PRK13919 109 -------EAFDLPGPGLDEEGHLDRTRLGRALKALSPEERRVIEVLYYQGYTHREAAQLLGLPLGTLKTRARRALSRLKE 181

                 ....
gi 896410632 182 KLLD 185
Cdd:PRK13919 182 VLRE 185
Sig-70_gvs1 TIGR02989
RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma ...
15-181 5.05e-10

RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are abundantly found in the species Rhodopirellula baltica (11), and Verrucomicrobium spinosum (16) and to a lesser extent in Gemmata obscuriglobus (2).


Pssm-ID: 274379 [Multi-domain]  Cd Length: 159  Bit Score: 56.56  E-value: 5.05e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   15 ERFTADAMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQG 94
Cdd:TIGR02989   1 KAFVRLLTRHERALRAFVRSLVADRDDVDDVLQETFVVAWRKFDQFDPGTNFVAWARGIARNKVLNYRRKLGRDRLVFDD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   95 ETVEdwQLAQAGEHDAVGLRSAEVEALsalpntevREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHR 174
Cdd:TIGR02989  81 DLLE--ALAAEAEPTEAERLSDDRQAL--------EGCLEKLPERQRELLDLRYQRGQKATALAEQTGRTVNAVYKALQR 150

                  ....*..
gi 896410632  175 GRRILRE 181
Cdd:TIGR02989 151 IRVSLRE 157
Sig70_famx1 TIGR02943
RNA polymerase sigma-70 factor, TIGR02943 family; This group of sigma factors are members of ...
23-183 5.08e-10

RNA polymerase sigma-70 factor, TIGR02943 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building, bidirectional best hits and one-to-a-genome distribution, to represent a conserved family.


Pssm-ID: 274359 [Multi-domain]  Cd Length: 188  Bit Score: 57.08  E-value: 5.08e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   23 QYVDQLYAAALRMS----RNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQ-GETV 97
Cdd:TIGR02943   6 QELEQLRRDLLRFArlqlRDRDLAEDAVQETLLAALSHRDSFAGRSALKTWLFAILKNKIIDALRAKGREVKVSDlDDEL 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   98 EDWQL----AQAGEHDAVGLRSAEVEALSALPNTE---VREA-LNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVM 169
Cdd:TIGR02943  86 DDEAFnalfTQNGHWAQHGQPQHWNTPEKQLENKEfweVFEAcLYHLPEQTARVFMMREVLGFESDEICQELEISTSNCH 165
                         170
                  ....*....|....
gi 896410632  170 SRLHRGRRILREKL 183
Cdd:TIGR02943 166 VLLYRARLSLRACL 179
PRK12517 PRK12517
RNA polymerase sigma factor; Provisional
28-183 6.16e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 183569 [Multi-domain]  Cd Length: 188  Bit Score: 57.00  E-value: 6.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  28 LYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVEDwQLAQAGE 107
Cdd:PRK12517  36 IYRYAYWLCKDKHIAEDLVQETFLRAWRSLDSLKDEKAAKAWLITILRRENARRFERKQFDLVDIEDDSIED-DASHSSE 114
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896410632 108 HDavglrsaevealsaLPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:PRK12517 115 EE--------------MEQEWLRRQIAKLDPEYREPLLLQVIGGFSGEEIAEILDLNKNTVMTRLFRARNQLKEAL 176
PRK12532 PRK12532
RNA polymerase sigma factor; Provisional
26-183 1.08e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 171564 [Multi-domain]  Cd Length: 195  Bit Score: 56.48  E-value: 1.08e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  26 DQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVE------D 99
Cdd:PRK12532  17 LLLHFARLQLPDHPDLAEDLVQETLLSAYSAGDSFQGRALVNSWLFAILKNKIIDALRQIGRQRKVFTLLDDElldeafE 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 100 WQLAQAGEHDAVGLRSAEVEALSALPNTEVRE----ALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRG 175
Cdd:PRK12532  97 SHFSQNGHWTPEGQPQHWNTPEKSLNNNEFQKilqsCLYNLPENTARVFTLKEILGFSSDEIQQMCGISTSNYHTIMHRA 176

                 ....*...
gi 896410632 176 RRILREKL 183
Cdd:PRK12532 177 RESLRQCL 184
PRK09642 PRK09642
RNA polymerase sigma factor;
24-181 1.78e-09

RNA polymerase sigma factor;


Pssm-ID: 170031 [Multi-domain]  Cd Length: 160  Bit Score: 55.11  E-value: 1.78e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  24 YVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQFtEGTNLKAWLYRILTNTYINLYRKRQREPqqsqgetvEDWQLA 103
Cdd:PRK09642   4 YRHYIFQVIFSILRHEEDAKDVTQEVFVKIHASLPNY-QFRGLKTWMARIATNHAIDYKRKKAREN--------EELSLC 74
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896410632 104 QAGEHDAVGLRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILRE 181
Cdd:PRK09642  75 KETEENIKSSHNIEDLLLTKEQKLLIAQKLRELPENYRDVVLAHYLEEKSYQEIALQEKIEVKTVEMKLYRARKWIKK 152
PRK09649 PRK09649
RNA polymerase sigma factor SigC; Reviewed
38-179 4.02e-09

RNA polymerase sigma factor SigC; Reviewed


Pssm-ID: 137458 [Multi-domain]  Cd Length: 185  Bit Score: 54.66  E-value: 4.02e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  38 NSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVEdwQLAQAGEHdAVGLRS-A 116
Cdd:PRK09649  46 DVGSADDLTQETFLRAIGAIPRFSARSSARTWLLAIARHVVADHIRHVRSRPRTTRGARPE--HLIDGDRH-ARGFEDlV 122
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 896410632 117 EVEALSALPNTEVREALnelsedfrmvvYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRIL 179
Cdd:PRK09649 123 EVTTMIADLTTDQREAL-----------LLTQLLGLSYADAAAVCGCPVGTIRSRVARARDAL 174
PRK12537 PRK12537
RNA polymerase sigma factor; Provisional
27-181 4.20e-09

RNA polymerase sigma factor; Provisional


Pssm-ID: 171568 [Multi-domain]  Cd Length: 182  Bit Score: 54.40  E-value: 4.20e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  27 QLYAAALRMSRNSADAEDLVQETYMKAFASYHQF--TEGTNlKAWLYRILTNTYINLYRKRQREPQQSQG--ETVEDWQL 102
Cdd:PRK12537  35 RLLGVARRIVRDRALAEDIVHDAFIKIWTGAASFdpARGSA-RGWIYSVTRHLALNVLRDTRREVVLDDDaeETAQTLHE 113
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896410632 103 AQAgehdavglrsaEVEALSALpnTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILRE 181
Cdd:PRK12537 114 IID-----------DFDLWANS--GKIHRCLEQLEPARRNCILHAYVDGCSHAEIAQRLGAPLGTVKAWIKRSLKALRE 179
SigX4 TIGR02957
RNA polymerase sigma-70 factor, TIGR02957 family; This group of sigma factors are members of ...
23-182 9.67e-09

RNA polymerase sigma-70 factor, TIGR02957 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building and bidirectional best hits, to represent a conserved family. This family is found in a limited number of bacterial lineages. This family includes apparent paralogous expansion in Streptomyces coelicolor A3(2), and multiple copies in Mycobacterium smegmatis MC2, Streptomyces avermitilis MA-4680 and Nocardia farcinica IFM10152.


Pssm-ID: 132002 [Multi-domain]  Cd Length: 281  Bit Score: 54.67  E-value: 9.67e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   23 QYVDQLYAAALRMSRNSADAEDLVQETymkaFASYHQFTEG--TNLKAWLYRILTNTYINLYR--KRQREpqqsqgETVE 98
Cdd:TIGR02957   5 ALRPLLFSLAYRMLGSVADAEDIVQET----FLRWQEADRAqiENPKAYLTKVVTRRCIDVLRsaRARRE------VYVG 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   99 DW-QLAQAGEHDAVGLRSAEVEALSalpnTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRR 177
Cdd:TIGR02957  75 PWlPEPLLTTSADPAESVELAESLS----MAYLLLLERLSPLERAVFVLREVFDYPYEEIASIVGKSEANCRQLVSRARR 150

                  ....*
gi 896410632  178 ILREK 182
Cdd:TIGR02957 151 HLDAR 155
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
132-181 1.22e-08

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 49.73  E-value: 1.22e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 896410632  132 ALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILRE 181
Cdd:pfam04545   1 ALASLPPRERQVLVLRYGEGLTLEEIGERLGISRERVRQIEKRALRKLRK 50
PRK12515 PRK12515
RNA polymerase sigma factor; Provisional
29-191 1.47e-08

RNA polymerase sigma factor; Provisional


Pssm-ID: 183567 [Multi-domain]  Cd Length: 189  Bit Score: 53.20  E-value: 1.47e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  29 YAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREP-QQSQGETVEDwqlaQAGE 107
Cdd:PRK12515  36 YRFGLRLVRDEQTAEDLVSEVFLDVWRQAGQFEGRSQVSTWLLSIARFKALSALRRRKHEEiDDEAAAAIED----GADT 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 108 HDAVGLRSAEVEALsalpntevREALNELSEDFRMV---VYYsdvEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKLL 184
Cdd:PRK12515 112 PEVALQKSDTSAAL--------RACLAKLSPAHREIidlVYY---HEKSVEEVGEIVGIPESTVKTRMFYARKKLAELLK 180

                 ....*..
gi 896410632 185 DYARENG 191
Cdd:PRK12515 181 AAGVERG 187
PRK12531 PRK12531
RNA polymerase sigma factor; Provisional
20-183 1.59e-08

RNA polymerase sigma factor; Provisional


Pssm-ID: 105726 [Multi-domain]  Cd Length: 194  Bit Score: 53.01  E-value: 1.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  20 DAMQYVDQLYAAALRM-----SRNSADAEDLVQETYMKAFASYHQFT-EGTNLKAWLYRILTNTYINLYRKRQREPQQSQ 93
Cdd:PRK12531  27 QAFALVFSYYAPKLKQfamkhVGNEQVAMEMVQETMSTVWQKAHLFDgQKSALSTWIYTIIRNLCFDLLRKQKGKDLHIH 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  94 GETV--EDWQlaqagEHDAVGLRSAEVEALSAlpntEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSR 171
Cdd:PRK12531 107 ADDIwpSDYY-----PPDLVDHYSPEQDMLKE----QVMKFLDRLPKAQRDVLQAVYLEELPHQQVAEMFDIPLGTVKSR 177
                        170
                 ....*....|..
gi 896410632 172 LhrgrRILREKL 183
Cdd:PRK12531 178 L----RLAVEKL 185
PRK12524 PRK12524
RNA polymerase sigma factor; Provisional
29-183 1.21e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 183573 [Multi-domain]  Cd Length: 196  Bit Score: 50.66  E-value: 1.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  29 YAAALRMSRNSADAEDLVQETYMKAFASYHQFTEG-TNLKAWLYRILTNTYINlyRKRQREPQQSQGETVEDWQLAQAGE 107
Cdd:PRK12524  40 LAVATRVLGDRAEAEDVTQEAMLRLWRIAPDWRQGeARVSTWLYRVVCNLCTD--RLRRRRRASVDLDDAPEPADAAPGA 117
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896410632 108 HDAVgLRSAEVEALSAlpntevreALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:PRK12524 118 EEAL-IEGDRMRALDA--------ALAALPERQRQAVVLRHIEGLSNPEIAEVMEIGVEAVESLTARGKRALAALL 184
PRK12539 PRK12539
RNA polymerase sigma factor SigF;
7-179 1.54e-07

RNA polymerase sigma factor SigF;


Pssm-ID: 237132 [Multi-domain]  Cd Length: 184  Bit Score: 50.11  E-value: 1.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   7 AADTRELRERFTADAMQYvdqlYAAAL-RMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKR 85
Cdd:PRK12539  20 AAAHRALLERLSGHLRAY----YKGKLaRIGRGAEEAEDLVQEALMAIHTRRHTYDPEQPLTPWVYAIARYKLIDHLRRT 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  86 QRepqqsqgeTVEDWQLAQAGE---HDAvglrSAEVEalSALpntEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILD 162
Cdd:PRK12539  96 RA--------SLADVPIDDADElvaHDD----HAAVE--STL---DLGRLLARLPEKMRLAIQAVKLEGLSVAEAATRSG 158
                        170
                 ....*....|....*..
gi 896410632 163 IPLGTVMSRLHRGRRIL 179
Cdd:PRK12539 159 MSESAVKVSVHRGLKAL 175
PRK12512 PRK12512
RNA polymerase sigma factor; Provisional
41-183 2.06e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 171551 [Multi-domain]  Cd Length: 184  Bit Score: 49.70  E-value: 2.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  41 DAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVEDWQLAQAGEhdavglrsaevea 120
Cdd:PRK12512  52 QAEDIVQEILLAVHLKRHTWDPGAPFAPWLFAIARNKLIDALRRRGRRVFVDIDDFAETLPAEPATE------------- 118
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 896410632 121 lsALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:PRK12512 119 --TLPAGDVGRHLETLPPRQRDVVQSISVEGASIKETAAKLSMSEGAVRVALHRGLAALAAKF 179
PRK12530 PRK12530
RNA polymerase sigma factor; Provisional
37-87 2.44e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 237128 [Multi-domain]  Cd Length: 189  Bit Score: 49.38  E-value: 2.44e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 896410632  37 RNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQR 87
Cdd:PRK12530  29 KDADLAEDVVQEALVSAYKNADSFKGQSALKTWIFAILKNKIIDLIRYRKR 79
PRK12542 PRK12542
RNA polymerase sigma factor; Provisional
24-177 3.74e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 183581 [Multi-domain]  Cd Length: 185  Bit Score: 48.89  E-value: 3.74e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  24 YVDQLYAAALRMSRNSADAEDLVQETYM---KAFASYHQFTEgTNLKAWLYRILTNTYINLYRKR----------QREPQ 90
Cdd:PRK12542  18 YEQKVYYVAYSILNNIQQAEDAVQETFItlyKNLEKLHSLNT-QELKRYILRVAKNKAIDSYRKNkrhetfleeyERESI 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  91 QSQGETVEDWQLAQAGEhdavglrsAEVEALsalpntevreaLNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMS 170
Cdd:PRK12542  97 EAVDENIEEWEKRKMSE--------VQIDTL-----------LKELNESNRQVFKYKVFYNLTYQEISSVMGITEANVRK 157

                 ....*..
gi 896410632 171 RLHRGRR 177
Cdd:PRK12542 158 QFERARK 164
PRK09646 PRK09646
ECF RNA polymerase sigma factor SigK;
29-183 6.12e-07

ECF RNA polymerase sigma factor SigK;


Pssm-ID: 182015 [Multi-domain]  Cd Length: 194  Bit Score: 48.51  E-value: 6.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  29 YAAALRMSRNSADAEDLVQETYMKAFASYHQF--TEGTNLkAWLyriLTNTYinlyRK---RQREPQQSQGETVEDWQLA 103
Cdd:PRK09646  44 YGLVRRVLRDPGYSEETTQEVYLEVWRTASRFdpARGSAL-AWL---LTLAH----RRavdRVRSEQAASQREVRYGARN 115
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 104 QAGEHDAVglrSAEVEALsaLPNTEVREALNELSEDFRMVV---YYSdveGFAYKDIAEILDIPLGTVMSRLHRGRRILR 180
Cdd:PRK09646 116 VDPAFDQV---AEEVEAR--LERERVRDCLDALTDTQRESVtlaYYG---GLTYREVAERLAVPLGTVKTRMRDGLIRLR 187

                 ...
gi 896410632 181 EKL 183
Cdd:PRK09646 188 DCL 190
PRK12535 PRK12535
RNA polymerase sigma factor; Provisional
42-176 6.17e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 237130 [Multi-domain]  Cd Length: 196  Bit Score: 48.35  E-value: 6.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  42 AEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGEtVEDwqlaQAGEHDAVGLRSAEVEAL 121
Cdd:PRK12535  51 ADDLTQETYLRVMSALPRFAARSSARTWLLSLARRVWVDNIRHDMARPRKSATE-YED----AAATTASNETTGSWSEWI 125
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 896410632 122 salpntEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGR 176
Cdd:PRK12535 126 ------DVRTLIDALPPERREALILTQVLGYTYEEAAKIADVRVGTIRSRVARAR 174
PRK12534 PRK12534
RNA polymerase sigma factor; Provisional
4-175 9.27e-06

RNA polymerase sigma factor; Provisional


Pssm-ID: 183576 [Multi-domain]  Cd Length: 187  Bit Score: 45.05  E-value: 9.27e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632   4 TNTAADTRELRERFTadaMQYVDQLYAAALRMSRNSADAEDLVQETYMKAFASYHQF--TEGTNLkAWLYRILTNTYINL 81
Cdd:PRK12534  17 TATAGGDRHAFEALY---RQTSPKLFGVCLRMIPQRAEAEEVLQDVFTLIWHKAGQFdpSRARGL-TWLAMIARNKAIDH 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  82 YRKRQrePQQsqgetvEDWQLAQAGEHDAVGlRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEIL 161
Cdd:PRK12534  93 LRANA--PQR------RNVALDDAGELRAAD-ASPLERTERASTRRRIDHCLAELEPPRSELIRTAFFEGITYEELAART 163
                        170
                 ....*....|....
gi 896410632 162 DIPLGTVMSRLHRG 175
Cdd:PRK12534 164 DTPIGTVKSWIRRG 177
PRK12544 PRK12544
RNA polymerase factor sigma-70;
37-183 1.83e-05

RNA polymerase factor sigma-70;


Pssm-ID: 183583 [Multi-domain]  Cd Length: 206  Bit Score: 44.41  E-value: 1.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  37 RNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVEDWQLAQAGEHDAVGL-RS 115
Cdd:PRK12544  40 SDLHLAEDAVQEALIGALKNADSFAGRAAFKTWVFAILKNKIIDLLRQKKRHVSASSLLRDEEEEEDFEELFDESGHwQK 119
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 896410632 116 AEVEALSALPNTEVREA---------LNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:PRK12544 120 DERPQAWGNPEESLEQEqfwrifeacLDGLPAKYARVFMMREFIELETNEICHAVDLSVSNLNVLLYRARLRLRECL 196
PRK12545 PRK12545
RNA polymerase factor sigma-70;
24-108 2.21e-05

RNA polymerase factor sigma-70;


Pssm-ID: 183584 [Multi-domain]  Cd Length: 201  Bit Score: 44.18  E-value: 2.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  24 YVDQLYAAALRMSR----NSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQS------Q 93
Cdd:PRK12545  13 YLAQLRHDLLRFARlqlrDADAAEDAVQEALAAAWSQAGRFAGQSAHKTWVFGILRNKLIDTLRARQRTVNLSaldaelD 92
                         90
                 ....*....|....*
gi 896410632  94 GETVEDWQLAQAGEH 108
Cdd:PRK12545  93 GEALLDRELFKDNGH 107
PRK12526 PRK12526
RNA polymerase sigma factor; Provisional
38-185 2.64e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 237127 [Multi-domain]  Cd Length: 206  Bit Score: 43.64  E-value: 2.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  38 NSADAEDLVQETYMKAFASYHQFTEGTNL-KAWLYRILTNTYINLYRKRQREPQQSQGETVedWQLAQAgehdAVGLRSA 116
Cdd:PRK12526  61 NEAQANELVQETMSNVWRKAHLYNGDKGAaTTWVYTVMRNAAFDMLRKIKAKKEQNLGDDI--WPIEQA----LAESQSE 134
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 896410632 117 EVEALSALPNTEVREALNELSEDFRMVV---YYSDVegfAYKDIAEILDIPLGTVMSRLHRGRRILREKLLD 185
Cdd:PRK12526 135 SEEFSDHLMDKQILSYIEKLPEAQQTVVkgvYFQEL---SQEQLAQQLNVPLGTVKSRLRLALAKLKVQMGE 203
PRK09636 PRK09636
RNA polymerase sigma factor SigJ; Provisional
27-163 5.08e-05

RNA polymerase sigma factor SigJ; Provisional


Pssm-ID: 236600 [Multi-domain]  Cd Length: 293  Bit Score: 43.37  E-value: 5.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  27 QLYAAALRMSRNSADAEDLVQETYMKAFASyhQFTEGTNLKAWLYRILTNTYINLYR--KRQREpqQSQGE-----TVED 99
Cdd:PRK09636  16 HLLSVAYRMLGSVADAEDIVQEAWLRWNNA--DRAQIRDPRAWLTRVVTRLCLDRLRsaRHRRE--TYVGPwlpepVVEE 91
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896410632 100 WQLAQAGEHDAVGLRsaeveaLSALpntevrEALNELSEDFRMVVYYSDVEGFAYKDIAEILDI 163
Cdd:PRK09636  92 LDDPLEAVVAAEDLS------LALM------LALERLSPLERAAFLLHDVFGVPFDEIASTLGR 143
PRK06811 PRK06811
RNA polymerase factor sigma-70; Validated
33-184 7.58e-05

RNA polymerase factor sigma-70; Validated


Pssm-ID: 180707 [Multi-domain]  Cd Length: 189  Bit Score: 42.23  E-value: 7.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  33 LRMSRNSADAEDLVQETYMKAFASYHQFT-EGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVEDwqlaqagehdaV 111
Cdd:PRK06811  39 LGTVNYSQLIEECVNDIFLSIWNNIDKFDeEKGSFKKWIAAISKYKAIDYKRKLTKNNEIDSIDEFIL-----------I 107
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 896410632 112 GLRSAEVEALSALPNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKLL 184
Cdd:PRK06811 108 SEESIENEIILKENKEEILKLINDLEKLDREIFIRRYLLGEKIEEIAKKLGLTRSAIDNRLSRGRKKLQKNKL 180
PRK06704 PRK06704
RNA polymerase subunit sigma-70;
35-180 1.62e-04

RNA polymerase subunit sigma-70;


Pssm-ID: 180663 [Multi-domain]  Cd Length: 228  Bit Score: 41.55  E-value: 1.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  35 MSRNSADAEDLVQETYMKAFASYhqfTEGTNLKAWLYRILTNTYINLYRKRQREPQQSQGETVEDWQLAQAGEHDAVGlr 114
Cdd:PRK06704  37 LTKNKWDGEDLAQETVCKVLQKY---SNKDICMTLVYKIARNRWLDQIKSKSVHEKIRDQITFEEPHEKIADLHEMVG-- 111
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896410632 115 saevealsalpntevrEALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILR 180
Cdd:PRK06704 112 ----------------KVLSSLNVQQSAILLLKDVFQYSIADIAKVCSVSEGAVKASLFRSRNRLK 161
PRK12536 PRK12536
RNA polymerase sigma factor; Provisional
34-183 1.66e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 237131 [Multi-domain]  Cd Length: 181  Bit Score: 41.19  E-value: 1.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  34 RMSRNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQRepQQSQGETVEDwqlaqagEHDAvgL 113
Cdd:PRK12536  41 RLPQLPDEVEDLVQEILLAVHNARHTYRADQPLTAWVHAIARYKLMDFLRSRAR--REALHDPLDD-------ESEL--F 109
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 114 RSAEVEALSAlpNTEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRRILREKL 183
Cdd:PRK12536 110 ATSDDEAAEA--RRDLGKLLEQLPDRQRLPIVHVKLEGLSVAETAQLTGLSESAVKVGIHRGLKALAAKI 177
PRK07037 PRK07037
extracytoplasmic-function sigma-70 factor; Validated
27-163 7.39e-04

extracytoplasmic-function sigma-70 factor; Validated


Pssm-ID: 180803 [Multi-domain]  Cd Length: 163  Bit Score: 38.90  E-value: 7.39e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  27 QLYAAALRMSRNSADAEDLVQETYMKAFASYHQFTEGTNLkAWLYRILTNTYINLYRKRQREpqqsqgetvedwQLAQAG 106
Cdd:PRK07037  10 MLVKIAARIVGCRSRAEDVVQDAFVKLVEAPNQDAVKQPV-AYLFRIVRNLAIDHYRRQALE------------NKYHGD 76
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896410632 107 EHDAVGLRSAEVEALSALPNTE----VREALNELSEDFRMVVYYSDVEGFAYKDIAEILDI 163
Cdd:PRK07037  77 EEDGLDVPSPEASPEAALINRDtlrhVADALSELPARTRYAFEMYRLHGETQKDIARELGV 137
PRK12529 PRK12529
RNA polymerase sigma factor; Provisional
42-175 1.09e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 183574 [Multi-domain]  Cd Length: 178  Bit Score: 38.76  E-value: 1.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  42 AEDLVQETYMKAFASyHQFTEGTNL---KAWLYRILTNTYINlYRKRQrEPQQSQGETVEdwQLAQAgEHDAVGLRSAEV 118
Cdd:PRK12529  42 ADDLAHDIFLRILAS-RDGGQREAIrqpRAYLARIANCVLVS-WRRRQ-SLELAWLEALA--TLPEP-LHPSPEQQSVIL 115
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 896410632 119 EALSalpntEVREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRG 175
Cdd:PRK12529 116 ETLH-----EIDALLDTLRPRVKQAFLMATLDGMKQKDIAQALDIALPTVKKYIHQA 167
PRK12520 PRK12520
RNA polymerase sigma factor; Provisional
37-105 1.98e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 237126 [Multi-domain]  Cd Length: 191  Bit Score: 38.17  E-value: 1.98e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896410632  37 RNSADAEDLVQETYMKAFASYHQFTEGTNLKAWLYRILTNTYINLYRKRQREPQQS--QGETVEDWQLAQA 105
Cdd:PRK12520  24 RDPALAEDAVSETLLAVLEHPERFAGQSSLKTYLVGILKHKIIDAIRSGRREVRLSldDADEQSDDDLFDA 94
sigI PRK09635
RNA polymerase sigma factor SigI; Provisional
32-177 2.73e-03

RNA polymerase sigma factor SigI; Provisional


Pssm-ID: 182008 [Multi-domain]  Cd Length: 290  Bit Score: 38.41  E-value: 2.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  32 ALRMSRNSADAEDLVQETYMKAFASyhQFTEGTNLKAWLYRI---LTNTYINLYRKRQREPQQSQGETVEDWQLAQAGEH 108
Cdd:PRK09635  22 AFRMVGDIGVAEDMVQEAFSRLLRA--PVGDIDDERGWLIVVtsrLCLDHIKSASTRRERPQDIAAWHDGDASVSSVDPA 99
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 896410632 109 DAVGLrsaevealsalpNTEVREALNE----LSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRR 177
Cdd:PRK09635 100 DRVTL------------DDEVRLALLImlerLGPAERVVFVLHEIFGLPYQQIATTIGSQASTCRQLAHRARR 160
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
82-185 3.08e-03

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 37.88  E-value: 3.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  82 YRKRQREPQQSQGETVEDWQLAQAGEHDAVGLRSAEVEALSALPNTEVREALNELSEDFRMVV--YYsdVEGFAYKDIAE 159
Cdd:COG1191  133 VQEALEAANAYQLLSLDEPLEDGDDLLDLLESGDPEEELEHEELREALAEAIEQLPERERLVLslYY--FEELTLKEIAE 210
                         90       100
                 ....*....|....*....|....*..
gi 896410632 160 ILDIPLGTVmSRLH-RGRRILREKLLD 185
Cdd:COG1191  211 VLGVSESRV-SRLHkKALARLREYLKE 236
PRK09047 PRK09047
RNA polymerase factor sigma-70; Validated
37-186 3.85e-03

RNA polymerase factor sigma-70; Validated


Pssm-ID: 236367 [Multi-domain]  Cd Length: 161  Bit Score: 36.87  E-value: 3.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632  37 RNSADAEDLVQETYMKAFASYHQFTEgTNLKAWLYRILTNTYINLYRKRQR-------------EPQQSQGETVEDWQLA 103
Cdd:PRK09047   2 RDDDAALDIVQDAMIKLAEKYGDRPA-AEWPPLFQRILQNRIHDWFRRQKVrntwvslfssfsdDDDDDDFDPLETLDSA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896410632 104 QAGEHDAVG-LRSAEV-----EALSALPNTEvREAlnelsedFRMVVYysdvEGFaykDIAE---ILDIPLGTVMSRLHR 174
Cdd:PRK09047  81 DEGAESPADkLERAQVlqlieEAIQKLPARQ-REA-------FLLRYW----EDM---DVAEtaaAMGCSEGSVKTHCSR 145
                        170
                 ....*....|..
gi 896410632 175 GRRILREKLLDY 186
Cdd:PRK09047 146 ATHALAKALEAK 157
PRK06930 PRK06930
positive control sigma-like factor; Validated
129-177 4.89e-03

positive control sigma-like factor; Validated


Pssm-ID: 180757 [Multi-domain]  Cd Length: 170  Bit Score: 36.63  E-value: 4.89e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 896410632 129 VREALNELSEDFRMVVYYSDVEGFAYKDIAEILDIPLGTVMSRLHRGRR 177
Cdd:PRK06930 108 IEDALSVLTEREKEVYLMHRGYGLSYSEIADYLNIKKSTVQSMIERAEK 156
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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