|
Name |
Accession |
Description |
Interval |
E-value |
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
11-844 |
2.98e-58 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 210.87 E-value: 2.98e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 11 AVLVALVAGVASTATAQAQEATNLDRISVTGSRIKSTDIETSQPVLSLTRADIEKQGVTSVADILQRVAAngaaLNRTFN 90
Cdd:COG4771 4 ASLLLLLALAAQAADALAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPG----VSVTRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 91 NGGDGSAGVSLRNLGAERTLVLVNGRRWTTG-LDGSVDLNTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITKQNFDG 169
Cdd:COG4771 80 GGRGGSSGISIRGLGGDRVLVLIDGVPVNNPaLGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 170 AEVNAYkGQYSAGDGQREAYDFTLGTVTDRASITVGASYvneksvmagdrkisaggppffsgqsatgipgsyvrngnqyv 249
Cdd:COG4771 160 LEGSVS-LGYGSNGNGTYSGSLSLGGPGDKLSFLLSGSY----------------------------------------- 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 250 iingvetpFDANVHGYNTAPDNYLLTPNERTSLFVLGSYNVTDNITFRTEAMYNERKSEqllasmpvtgqrlsagsmynp 329
Cdd:COG4771 198 --------RDRDGYLDYRNGGFVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRD--------------------- 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 330 YGVDLTGVNRRFNeSGGRSFNQNVKNWHFYGGFEGFFefadrNFDWDVGYRYDKTDQNDLTYGLFNRQRlaeaygpsalr 409
Cdd:COG4771 249 GGPPTLGDTEISS-DNAGDRDTTTDRGNYSLRYNGDL-----GDNLDLSLYYSRTDRDSTNGSLGGSTG----------- 311
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 410 dgkpvclnsagaviagcvpinplgglgsiSQEALDYTSFTAhdsaslvskgyyaniSGEIVQLPAGALGFAAGYEYRKET 489
Cdd:COG4771 312 -----------------------------SFSDSDDTTYGL---------------ELDLTYPLGGNHTLTLGAEYRYDD 347
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 490 gqfdpdafiasgLSTGNGAAPTKGGYDLNEFFVELSIPVLADlpgaklLDFSVASRYSDYSNFGNTTNN----KFGFRWK 565
Cdd:COG4771 348 ------------LDSSSFLGGADASRDTYGLFAQDEWKLTDK------LTLTAGLRYDYYSTFGASNYTafspRLGLRYD 409
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 566 PIDDLMIRGNYSEGFRAPSINNLYRGDTDSFETYIdpcssnaglrtgavaaqcaaqgvpanfvqpgagagrkqtvvpftw 645
Cdd:COG4771 410 LSDNLTLRASYGRGFRAPSLAELYGSGTGTPGRYV--------------------------------------------- 444
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 646 QANPNLKPETSTSKTLGLVWSPSFvTGLNVTLDWWQIKVEDAITrpaiqdimsycyggtpqqqaaycgLITRDPNYGTVN 725
Cdd:COG4771 445 LGNPDLKPETSDNYELGLEYRLGN-GGLSLSLTGFYTDIKDLIV------------------------LVPVGPGPGDVL 499
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 726 QrytitnvnmpLQNLASYKVEGWDLGLAYRLPETSFGQFTISWdstylskwdTKSTQDspvEGRQGRYRDQDPYWRIrsN 805
Cdd:COG4771 500 Q----------YENVGKARTYGLELELKYRLGKGLTLTASYTY---------LDSKID---DGDTGEPLPNVPPHKA--N 555
|
810 820 830
....*....|....*....|....*....|....*....
gi 896543840 806 LYVDWSYGDFGVNWGLRYKSGMREECPFDPAQDPETFPF 844
Cdd:COG4771 556 LGLDYRLPKWWLLLLLTRYYGGRYVTPPSGRLEGYTPGY 594
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
54-917 |
3.05e-58 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 211.54 E-value: 3.05e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 54 PVLSLTRADIEKQGVTSVADILQRVAanGAALNRtfnNGGDGSAGVSLRNLGAERTLVLVNGRRWTTGLDG-SVDLNTIP 132
Cdd:cd01347 1 SVSVITAEDIEKQPATSLADLLRRIP--GVSVTR---GGGGGGSTISIRGFGPDRTLVLVDGLPLASSNYGrGVDLNTIP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 133 TAMIERIDILKDGASTIYGSDAIAGVVNIITK--QNFDGAEVNAYKGQYSAGDGQREAYDFTLGTVTDRAsitvgasyvn 210
Cdd:cd01347 76 PELIERVEVLKGPSSALYGSGAIGGVVNIITKrpTDEFGGSVTAGYGSDNSGSSGGGGFDVSGALADDGA---------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 211 eksvmagdrkisaggppfFSGQSAtgipGSYVRNGNQYVIINGVETpfdanvhgyntapdnyllTPNERTSLFVLGSYNV 290
Cdd:cd01347 146 ------------------FGARLY----GAYRDGDGTIDGDGQADD------------------SDEERYNVAGKLDWRP 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 291 TDNITFRTEAMYNERKSEQLLASMPVTGQRLSAGSMY--NPYGVDLTGVNRRFNESGGRSFNQNVKNWHFyggfegffef 368
Cdd:cd01347 186 DDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPssNTNGDRDWDYRDRYRKRASLGLEHDLNDTGW---------- 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 369 adrNFDWDVGYRYDKTDQNDLTYGLFNRqrlaeaygpsalrdgkpvclnsagaviagcVPINPLGGLGSISQEALDYTSF 448
Cdd:cd01347 256 ---TLRANLSYSYTDNDGDPLILNGGNN------------------------------AAGGDLGRSGYSSERDTTQLGF 302
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 449 TAHDSASLvskgyyanisgeivQLPAGALGFAAGYEYRKEtgqfdpdafiasglstgngaaptKGGYDLNEFFVELSIPV 528
Cdd:cd01347 303 DAGLNAPF--------------GTGPVAHTLTLGVEYRRE-----------------------ELDEKQTALYAQDTIEL 345
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 529 LADlpgaklLDFSVASRYSDYSN--------------FGNTTNNKFGFRWKPIDDLMIRGNYSEGFRAPSINNLYRGdtd 594
Cdd:cd01347 346 TDD------LTLTLGLRYDHYDQdskdtiaggttakkSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGG--- 416
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 595 sfetyidpcssnaglrtgavaaqcaaqgvpanfvqpgagagrkQTVVPFTWQANPNLKPETSTSKTLGLVWSPsfVTGLN 674
Cdd:cd01347 417 -------------------------------------------GSHGGTAAVGNPNLKPEKSKQYELGLKYDP--GDGLT 451
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 675 VTLDWWQIKVEDAITRPaiqdimsycyggtpqqqaaycglitrdpnyGTVNQRYTITNVNmplqNLASYKVEGWDLGLAY 754
Cdd:cd01347 452 LSAALFRIDIKNEIVST------------------------------PTNTGLGLVTVYV----NGGKARIRGVELEASY 497
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 755 RLPETSFGQFTISWDSTYLSKWDTKSTqdspvegrqGRYRDQDPYWRIRSNLYVDWSYGDFGVNWGLRYKSGMREecpfD 834
Cdd:cd01347 498 DLTDGLGLTGSYTYTDTEVKRTDGATT---------GNRLPGIPKHTANLGLDYELPDEGLTAGGGVRYRGKQYA----D 564
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 835 PAQDPETFpfcsdgakgenHIASTTYHDIQVRYNTPWKGTIMLGLNNAFDKDPPVSYSVRANMFDPqYDLPGRYMYMQYK 914
Cdd:cd01347 565 TANGNNTV-----------KVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSVRGSGLYG-YYGPGRTYYLSVS 632
|
...
gi 896543840 915 QKF 917
Cdd:cd01347 633 YKF 635
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
49-158 |
2.13e-29 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 112.75 E-value: 2.13e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 49 IETSQPVLSLTRADIEKQGVTSVADILQRVAanGAalnRTFNNGGDGSAGVSLRNLGAERTLVLVNGRRWTTGLDGSVDL 128
Cdd:pfam07715 3 RDTPGSVSVVTAEDIEDQGATNLADALRGVP--GV---SVSSGGGGGGSSISIRGFGSNRVLVLVDGVPLNSGGGGSVDL 77
|
90 100 110
....*....|....*....|....*....|
gi 896543840 129 NTIPTAMIERIDILKDGASTIYGSDAIAGV 158
Cdd:pfam07715 78 NSIDPEDIERVEVLKGPASALYGSGAIGGV 107
|
|
| TonB-hemin |
TIGR01785 |
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ... |
34-885 |
4.87e-28 |
|
TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273807 [Multi-domain] Cd Length: 665 Bit Score: 120.96 E-value: 4.87e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 34 LDRISVTGSRIKSTDIETSQPVLSLTRADIEKQGVTSVADILQRVAangaalNRTFNNGGDGSA-GVSLRNLGAERTLVL 112
Cdd:TIGR01785 1 LDTVTVTATRTRQVLSEAPASVSVISGEQIESKQANNLADALNTVP------GVDVTGGGRPPGqSINIRGLQDNRVLVV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 113 VNGRRWTTGLDGSVD-LNTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITK---------QNFdGAEVnayKGQYSAG 182
Cdd:TIGR01785 75 VDGARQNYQRGGAHNgSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKdaadllrpgQLF-GGLA---KLSYGSN 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 183 DGQREAYDFTLGTVTDRASITVGASYvneksvmagdrkisaggppffsgqsatgipgsyvRNGNQYVIINGVETPFDANV 262
Cdd:TIGR01785 151 NNSFGGSVAVAGRLDDNLDALVAATY----------------------------------RDGGNYRNGNKEEATNSAYV 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 263 HGYNTAPDNYLLTPNERTSLFVL---GSYNVTDNITFRTEAMYNErkSEQLLASmpvTGQRLSAGSMYNPYGVDLTGVNR 339
Cdd:TIGR01785 197 QKNLLAKLGWQLDDAQRLEFSYFtteGSLDEAQNSGPGTEYVLGS--SSTLLAS---STRDRSATLTYNWTPEDNPWLDA 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 340 RFNESGGRSFNQNVKNWHFYGgfegffefadrnfdwdvgyRYDKTDQNDLTYGLFNRQRLaeaygpsalrdgkpvclnsa 419
Cdd:TIGR01785 272 TASLYYNRTENDNDRSARGVG-------------------REEGYQYTTYGATLQNTSRF-------------------- 312
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 420 gaviagcvpinplgglgsisqealdytsftAHDSASLVSKGyyanisgeiVQlpagalgfaaGYEYRKETGQFDPdafia 499
Cdd:TIGR01785 313 ------------------------------DVASWSTLTYG---------VD----------WMKDKRRTESFDP----- 338
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 500 SGLSTGNGAAPTKGGYdLNEFFVELSIPVLAD----LPGAKLLDFSVASRYSDYSNFGNTTNNKF----GFRWKPIDDLM 571
Cdd:TIGR01785 339 NSVTTIVPNPPSAKEY-FFGLFLQDNIPLLDDrltlSAGLRYDHYKLSPKTTADTEAVDRSYSRWspslGLSYKPVDWLT 417
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 572 IRGNYSEGFRAPSInnlyrgdtdsFETYIDpcssnaglrtgavaaqcaaqgvpanfvqpGAGAGrkqTVVPFTWQANPNL 651
Cdd:TIGR01785 418 LYASYSQGFRAPSI----------DELYGT-----------------------------GDHPG---TPGGYTFAPNPNL 455
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 652 KPETSTSKTLGlvwspSFVTGLNVTLDWWQIKVEDAITRPAIQDIMSYCYGGTPQQQAaycglitrdpnygtvnQRYTIT 731
Cdd:TIGR01785 456 KPETSKTWELG-----ANLSFDNLLLDNDQLQFKVAYFYNDVKDFIDLTIGVTDNVTA----------------GMNNIT 514
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 732 NvnmpLQNLASYKVEGWDLGLAYRlpetsFGQFTISWDSTYLSKWDTKSTQdspvegrqgrYRDQDPYWRIRSNLYVDWS 811
Cdd:TIGR01785 515 Q----YVNIDGARIRGIEASASYD-----AGLWATGLSYGYTIGKDQNTNQ----------WLSNIPPLKLVVTVGYRFP 575
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896543840 812 YGDFGVNWGLRYKSGMREECPFDPAqdPETFPFCSDGAkgenhiastTYHDIQVRYN-TPWKG-TIMLGLNNAFDK 885
Cdd:TIGR01785 576 DRRLDLGAKAAYYERQSESPTTEDV--AANGLLTTPGY---------TVVDLYATYQpNAVKGlTVRFGVNNLTDR 640
|
|
| btuB |
PRK10641 |
TonB-dependent vitamin B12 receptor BtuB; |
14-233 |
6.57e-22 |
|
TonB-dependent vitamin B12 receptor BtuB;
Pssm-ID: 236730 [Multi-domain] Cd Length: 614 Bit Score: 101.22 E-value: 6.57e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 14 VALVAGVASTATAQAQEATNLDRISVTGSRIKstdietsQPVLSL-------TRADIEKQGVTSVADILQRVAanGAALN 86
Cdd:PRK10641 5 ASLLTALSVTAFSGWAQDTSPDTLVVTANRFQ-------QPVSTVlapttvvTRDDIDRWQSKSVNDVLRRLP--GVDIA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 87 RtfnNGGDG-SAGVSLRNLGAERTLVLVNGRRWT-TGLDGSVDLNTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITK 164
Cdd:PRK10641 76 Q---NGGLGqLSSLFIRGTNSSHVLVLIDGVRLNqAGISGSADLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITT 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896543840 165 QNFDGAEVNAYKG-----QYSAGDGQReaydftlgtVTDRASITVGASYVNEKSVmagdrKISAGGPPFFSGQS 233
Cdd:PRK10641 153 RDKPGTTLSAGWGsngyqNYDGSTQQQ---------LGDNTRVTLAGDYTYTKGF-----DVVAYGNTGTQAQP 212
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
11-844 |
2.98e-58 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 210.87 E-value: 2.98e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 11 AVLVALVAGVASTATAQAQEATNLDRISVTGSRIKSTDIETSQPVLSLTRADIEKQGVTSVADILQRVAAngaaLNRTFN 90
Cdd:COG4771 4 ASLLLLLALAAQAADALAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPG----VSVTRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 91 NGGDGSAGVSLRNLGAERTLVLVNGRRWTTG-LDGSVDLNTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITKQNFDG 169
Cdd:COG4771 80 GGRGGSSGISIRGLGGDRVLVLIDGVPVNNPaLGGGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 170 AEVNAYkGQYSAGDGQREAYDFTLGTVTDRASITVGASYvneksvmagdrkisaggppffsgqsatgipgsyvrngnqyv 249
Cdd:COG4771 160 LEGSVS-LGYGSNGNGTYSGSLSLGGPGDKLSFLLSGSY----------------------------------------- 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 250 iingvetpFDANVHGYNTAPDNYLLTPNERTSLFVLGSYNVTDNITFRTEAMYNERKSEqllasmpvtgqrlsagsmynp 329
Cdd:COG4771 198 --------RDRDGYLDYRNGGFVGNSGYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRD--------------------- 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 330 YGVDLTGVNRRFNeSGGRSFNQNVKNWHFYGGFEGFFefadrNFDWDVGYRYDKTDQNDLTYGLFNRQRlaeaygpsalr 409
Cdd:COG4771 249 GGPPTLGDTEISS-DNAGDRDTTTDRGNYSLRYNGDL-----GDNLDLSLYYSRTDRDSTNGSLGGSTG----------- 311
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 410 dgkpvclnsagaviagcvpinplgglgsiSQEALDYTSFTAhdsaslvskgyyaniSGEIVQLPAGALGFAAGYEYRKET 489
Cdd:COG4771 312 -----------------------------SFSDSDDTTYGL---------------ELDLTYPLGGNHTLTLGAEYRYDD 347
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 490 gqfdpdafiasgLSTGNGAAPTKGGYDLNEFFVELSIPVLADlpgaklLDFSVASRYSDYSNFGNTTNN----KFGFRWK 565
Cdd:COG4771 348 ------------LDSSSFLGGADASRDTYGLFAQDEWKLTDK------LTLTAGLRYDYYSTFGASNYTafspRLGLRYD 409
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 566 PIDDLMIRGNYSEGFRAPSINNLYRGDTDSFETYIdpcssnaglrtgavaaqcaaqgvpanfvqpgagagrkqtvvpftw 645
Cdd:COG4771 410 LSDNLTLRASYGRGFRAPSLAELYGSGTGTPGRYV--------------------------------------------- 444
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 646 QANPNLKPETSTSKTLGLVWSPSFvTGLNVTLDWWQIKVEDAITrpaiqdimsycyggtpqqqaaycgLITRDPNYGTVN 725
Cdd:COG4771 445 LGNPDLKPETSDNYELGLEYRLGN-GGLSLSLTGFYTDIKDLIV------------------------LVPVGPGPGDVL 499
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 726 QrytitnvnmpLQNLASYKVEGWDLGLAYRLPETSFGQFTISWdstylskwdTKSTQDspvEGRQGRYRDQDPYWRIrsN 805
Cdd:COG4771 500 Q----------YENVGKARTYGLELELKYRLGKGLTLTASYTY---------LDSKID---DGDTGEPLPNVPPHKA--N 555
|
810 820 830
....*....|....*....|....*....|....*....
gi 896543840 806 LYVDWSYGDFGVNWGLRYKSGMREECPFDPAQDPETFPF 844
Cdd:COG4771 556 LGLDYRLPKWWLLLLLTRYYGGRYVTPPSGRLEGYTPGY 594
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
54-917 |
3.05e-58 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 211.54 E-value: 3.05e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 54 PVLSLTRADIEKQGVTSVADILQRVAanGAALNRtfnNGGDGSAGVSLRNLGAERTLVLVNGRRWTTGLDG-SVDLNTIP 132
Cdd:cd01347 1 SVSVITAEDIEKQPATSLADLLRRIP--GVSVTR---GGGGGGSTISIRGFGPDRTLVLVDGLPLASSNYGrGVDLNTIP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 133 TAMIERIDILKDGASTIYGSDAIAGVVNIITK--QNFDGAEVNAYKGQYSAGDGQREAYDFTLGTVTDRAsitvgasyvn 210
Cdd:cd01347 76 PELIERVEVLKGPSSALYGSGAIGGVVNIITKrpTDEFGGSVTAGYGSDNSGSSGGGGFDVSGALADDGA---------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 211 eksvmagdrkisaggppfFSGQSAtgipGSYVRNGNQYVIINGVETpfdanvhgyntapdnyllTPNERTSLFVLGSYNV 290
Cdd:cd01347 146 ------------------FGARLY----GAYRDGDGTIDGDGQADD------------------SDEERYNVAGKLDWRP 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 291 TDNITFRTEAMYNERKSEQLLASMPVTGQRLSAGSMY--NPYGVDLTGVNRRFNESGGRSFNQNVKNWHFyggfegffef 368
Cdd:cd01347 186 DDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPssNTNGDRDWDYRDRYRKRASLGLEHDLNDTGW---------- 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 369 adrNFDWDVGYRYDKTDQNDLTYGLFNRqrlaeaygpsalrdgkpvclnsagaviagcVPINPLGGLGSISQEALDYTSF 448
Cdd:cd01347 256 ---TLRANLSYSYTDNDGDPLILNGGNN------------------------------AAGGDLGRSGYSSERDTTQLGF 302
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 449 TAHDSASLvskgyyanisgeivQLPAGALGFAAGYEYRKEtgqfdpdafiasglstgngaaptKGGYDLNEFFVELSIPV 528
Cdd:cd01347 303 DAGLNAPF--------------GTGPVAHTLTLGVEYRRE-----------------------ELDEKQTALYAQDTIEL 345
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 529 LADlpgaklLDFSVASRYSDYSN--------------FGNTTNNKFGFRWKPIDDLMIRGNYSEGFRAPSINNLYRGdtd 594
Cdd:cd01347 346 TDD------LTLTLGLRYDHYDQdskdtiaggttakkSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGG--- 416
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 595 sfetyidpcssnaglrtgavaaqcaaqgvpanfvqpgagagrkQTVVPFTWQANPNLKPETSTSKTLGLVWSPsfVTGLN 674
Cdd:cd01347 417 -------------------------------------------GSHGGTAAVGNPNLKPEKSKQYELGLKYDP--GDGLT 451
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 675 VTLDWWQIKVEDAITRPaiqdimsycyggtpqqqaaycglitrdpnyGTVNQRYTITNVNmplqNLASYKVEGWDLGLAY 754
Cdd:cd01347 452 LSAALFRIDIKNEIVST------------------------------PTNTGLGLVTVYV----NGGKARIRGVELEASY 497
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 755 RLPETSFGQFTISWDSTYLSKWDTKSTqdspvegrqGRYRDQDPYWRIRSNLYVDWSYGDFGVNWGLRYKSGMREecpfD 834
Cdd:cd01347 498 DLTDGLGLTGSYTYTDTEVKRTDGATT---------GNRLPGIPKHTANLGLDYELPDEGLTAGGGVRYRGKQYA----D 564
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 835 PAQDPETFpfcsdgakgenHIASTTYHDIQVRYNTPWKGTIMLGLNNAFDKDPPVSYSVRANMFDPqYDLPGRYMYMQYK 914
Cdd:cd01347 565 TANGNNTV-----------KVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSVRGSGLYG-YYGPGRTYYLSVS 632
|
...
gi 896543840 915 QKF 917
Cdd:cd01347 633 YKF 635
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
37-210 |
5.78e-39 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 146.17 E-value: 5.78e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 37 ISVTGSRIKSTDIETSQPVLSLTRADIEKQGVTSVADILQRVAanGAALNRtfNNGGDGSAGVSLRNLGAERTLVLVNGR 116
Cdd:COG4206 1 VVVTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALRRVP--GVQVSS--SGGPGSAASISIRGLGSNQTLVLIDGV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 117 RWTTGLDGSVDLNTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITKQNFDGAEVNAykgQYSAGDGQREAYDFTLGTV 196
Cdd:COG4206 77 PLNDPSLGGVDLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSV---SASYGSFGTRRLSASLSGG 153
|
170
....*....|....
gi 896543840 197 TDRASITVGASYVN 210
Cdd:COG4206 154 AGKFSYSLSASYRR 167
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
34-896 |
2.74e-38 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 152.67 E-value: 2.74e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 34 LDRISVTGSRIKSTDIETSQPVLSLTRADIEKQGVTSVADILQRVAangaalNRTFNNGGDGSAGVSLR--NLGAERTLV 111
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVP------GVSVTSAGGGAGQISIRgfGGGGNRVLV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 112 LVNGRRWTTGLDGSVDLNTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITKQNFDGAEVNAykgQYSAGDGQREAYDF 191
Cdd:COG1629 75 LVDGVPLNDPSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEV---SASYGSYGTYRASL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 192 TLGTVTDRASITVGASYVNEksvmagdrkisaggppffsgqsatgipGSYVRNGNQyviingvetpfdanvhgyntapdn 271
Cdd:COG1629 152 SLSGGNGKLAYRLSASYRDS---------------------------DGYRDNSDS------------------------ 180
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 272 ylltpnERTSLFVLGSYNVTDNITFRTEAMYNERKSEQ-LLASMPVTGQRLSAGSMYNPYGVDlTGVNRRFNESGGRSFN 350
Cdd:COG1629 181 ------DRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSpGYLTLAALRPRGAMDDGTNPYSND-TDDNTRDRYSLSLEYE 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 351 QNVKNWhfyggfegffefadrNFDWDVGYRYDKTDQNDLTYGLFNrqrlaeaygpsalrdgkpvclnsagaviagcvpin 430
Cdd:COG1629 254 HLGDGL---------------KLSASAYYRYDDTDLDSDFTPTPA----------------------------------- 283
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 431 plgGLGSISQEALDYTSFTahdsaslvskgyyANISGEIVQLPAGALGFAAGYEYRKETG-QFDPDAFIASG-LSTGNGA 508
Cdd:COG1629 284 ---DGGTLEQTDFDNRTYG-------------LELRLTYDLGFGGKHTLLVGLDYQRQDLdGSGYPLDLGSGsLPTLTSG 347
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 509 APTKGGYDLNEFFVELSIPVLADL---PGAKLLDFSVASRYSDYSNFGNTTNN-------KFGFRWKPIDDLMIRGNYSE 578
Cdd:COG1629 348 ADDDGTTTSLALYAQDTYKLTDKLtltAGLRYDYVSYDVDDTVTGTDSASGSRsysafspSLGLTYQLSPNLSLYASYSR 427
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 579 GFRAPSINNLYRGDTDSFetyidpcssnaglrtgavaaqcaaqgvpanfvqpgagagrkqtvvpftWQANPNLKPETSTS 658
Cdd:COG1629 428 GFRAPTFGELYANGTDPY------------------------------------------------SVGNPDLKPETSTN 459
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 659 KTLGLVWSPsFVTGLNVTLDWWQIKVEDaitrpaiqdimsycyggtpqqqaaycgLITRDPNYGTVNQRYTITNVnmplq 738
Cdd:COG1629 460 YELGLRYRL-LDGRLSLSLALFYSDVDN---------------------------EILSVPLPNDSGFSTYYTNA----- 506
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 739 nlASYKVEGWDLGLAYRLPETSFGQFTISW-DSTYLSKWDTKSTQDspvegrqGRYRDQDPYWRIRSNLYVDWSYGdFGV 817
Cdd:COG1629 507 --GKARSYGVELELSYQLTPGLSLNASYSYtDAKFDDDTDGSADLD-------GNRLPGVPPLTANLGLTYEFPGG-WSL 576
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 896543840 818 NWGLRYKSGMreecPFDPAQDPETFPfcsdgakgenhiaSTTYHDIQVRYNTPWKGTIMLGLNNAFDKDPPVSYSVRAN 896
Cdd:COG1629 577 GLGVRYVGDR----YLDDANTQGAPG-------------GYTLVDLGAGYRFGDNLTLSLGVDNLFDKKYATSLSVRAS 638
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
49-158 |
2.13e-29 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 112.75 E-value: 2.13e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 49 IETSQPVLSLTRADIEKQGVTSVADILQRVAanGAalnRTFNNGGDGSAGVSLRNLGAERTLVLVNGRRWTTGLDGSVDL 128
Cdd:pfam07715 3 RDTPGSVSVVTAEDIEDQGATNLADALRGVP--GV---SVSSGGGGGGSSISIRGFGSNRVLVLVDGVPLNSGGGGSVDL 77
|
90 100 110
....*....|....*....|....*....|
gi 896543840 129 NTIPTAMIERIDILKDGASTIYGSDAIAGV 158
Cdd:pfam07715 78 NSIDPEDIERVEVLKGPASALYGSGAIGGV 107
|
|
| TonB-hemin |
TIGR01785 |
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ... |
34-885 |
4.87e-28 |
|
TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273807 [Multi-domain] Cd Length: 665 Bit Score: 120.96 E-value: 4.87e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 34 LDRISVTGSRIKSTDIETSQPVLSLTRADIEKQGVTSVADILQRVAangaalNRTFNNGGDGSA-GVSLRNLGAERTLVL 112
Cdd:TIGR01785 1 LDTVTVTATRTRQVLSEAPASVSVISGEQIESKQANNLADALNTVP------GVDVTGGGRPPGqSINIRGLQDNRVLVV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 113 VNGRRWTTGLDGSVD-LNTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITK---------QNFdGAEVnayKGQYSAG 182
Cdd:TIGR01785 75 VDGARQNYQRGGAHNgSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKdaadllrpgQLF-GGLA---KLSYGSN 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 183 DGQREAYDFTLGTVTDRASITVGASYvneksvmagdrkisaggppffsgqsatgipgsyvRNGNQYVIINGVETPFDANV 262
Cdd:TIGR01785 151 NNSFGGSVAVAGRLDDNLDALVAATY----------------------------------RDGGNYRNGNKEEATNSAYV 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 263 HGYNTAPDNYLLTPNERTSLFVL---GSYNVTDNITFRTEAMYNErkSEQLLASmpvTGQRLSAGSMYNPYGVDLTGVNR 339
Cdd:TIGR01785 197 QKNLLAKLGWQLDDAQRLEFSYFtteGSLDEAQNSGPGTEYVLGS--SSTLLAS---STRDRSATLTYNWTPEDNPWLDA 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 340 RFNESGGRSFNQNVKNWHFYGgfegffefadrnfdwdvgyRYDKTDQNDLTYGLFNRQRLaeaygpsalrdgkpvclnsa 419
Cdd:TIGR01785 272 TASLYYNRTENDNDRSARGVG-------------------REEGYQYTTYGATLQNTSRF-------------------- 312
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 420 gaviagcvpinplgglgsisqealdytsftAHDSASLVSKGyyanisgeiVQlpagalgfaaGYEYRKETGQFDPdafia 499
Cdd:TIGR01785 313 ------------------------------DVASWSTLTYG---------VD----------WMKDKRRTESFDP----- 338
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 500 SGLSTGNGAAPTKGGYdLNEFFVELSIPVLAD----LPGAKLLDFSVASRYSDYSNFGNTTNNKF----GFRWKPIDDLM 571
Cdd:TIGR01785 339 NSVTTIVPNPPSAKEY-FFGLFLQDNIPLLDDrltlSAGLRYDHYKLSPKTTADTEAVDRSYSRWspslGLSYKPVDWLT 417
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 572 IRGNYSEGFRAPSInnlyrgdtdsFETYIDpcssnaglrtgavaaqcaaqgvpanfvqpGAGAGrkqTVVPFTWQANPNL 651
Cdd:TIGR01785 418 LYASYSQGFRAPSI----------DELYGT-----------------------------GDHPG---TPGGYTFAPNPNL 455
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 652 KPETSTSKTLGlvwspSFVTGLNVTLDWWQIKVEDAITRPAIQDIMSYCYGGTPQQQAaycglitrdpnygtvnQRYTIT 731
Cdd:TIGR01785 456 KPETSKTWELG-----ANLSFDNLLLDNDQLQFKVAYFYNDVKDFIDLTIGVTDNVTA----------------GMNNIT 514
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 732 NvnmpLQNLASYKVEGWDLGLAYRlpetsFGQFTISWDSTYLSKWDTKSTQdspvegrqgrYRDQDPYWRIRSNLYVDWS 811
Cdd:TIGR01785 515 Q----YVNIDGARIRGIEASASYD-----AGLWATGLSYGYTIGKDQNTNQ----------WLSNIPPLKLVVTVGYRFP 575
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 896543840 812 YGDFGVNWGLRYKSGMREECPFDPAqdPETFPFCSDGAkgenhiastTYHDIQVRYN-TPWKG-TIMLGLNNAFDK 885
Cdd:TIGR01785 576 DRRLDLGAKAAYYERQSESPTTEDV--AANGLLTTPGY---------TVVDLYATYQpNAVKGlTVRFGVNNLTDR 640
|
|
| TonB-hemlactrns |
TIGR01786 |
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ... |
35-908 |
6.33e-26 |
|
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273808 [Multi-domain] Cd Length: 715 Bit Score: 114.43 E-value: 6.33e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 35 DRISVTGSRIKSTDIETSQP----VLSLTRADIEKQGVTSVADILQRVAangaalNRTFNNGG-DGSAGVSLRNLGAERT 109
Cdd:TIGR01786 1 DTITVTATRTADPQRRDLSVtpasVSVISREQLKSQQVRNLRDLLRYEP------GVSVVEGGrGGSQGINIRGLDKNRV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 110 LVLVNGRRWTTGLDGS----VDLNTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITKQNFD--------GAEVnayKG 177
Cdd:TIGR01786 75 AVLVDGIRQNTSYGGQgstfYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADllkpgkdlGGLS---KL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 178 QYSAGDGQREAyDFTLGTVTDRASITVGASYVNEKSvmagdrkisaggppffsgqsatgipgsyVRNGNQYVIINGVETP 257
Cdd:TIGR01786 152 GYSSANNRFTQ-SVAAAGRNDDVDALVQATYRRGHE----------------------------LKNGNKANIGNESKRS 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 258 fDANVHGYNTAPD----NYLLTPNERTSLFVLGSYNVTDnitfRTEAMYNERKSEQLLASMPVTGQRLSAGSMY-NPYGV 332
Cdd:TIGR01786 203 -KPNPSDYKSQSFlaklGWQLNDAHRLGLSLEYTQTDYD----EPEMTNTSYLTKPLGAPLLSSTVVLGDSKTRdRRTGL 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 333 D--LTGVNRRFNESGGRSFNQNVKNWHFYGGFE-GFFEFADRNFDWDVGYRYD--KTDQNDLTygLFNRQRLAEAYGPSA 407
Cdd:TIGR01786 278 DyeLNPDNSWLDTVKLALDKQYIQLYNYLNATSaSDYPGVDKNGRYKDKYDYYtlGFDTNNKI--EFSVHSLSLTYGLDR 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 408 LRDgkpvcLNSAGAVIAGCV--PINPLGGLGSISQEALDYTSFTAHDSASLvskgyyanisGEIVQLPAGALgfaagYEY 485
Cdd:TIGR01786 356 FKD-----KVSTGDSRRNLPtaAYNLYGYEGENRPVKGSNFGLFLQDNIKL----------GDWLSLSAGLR-----YDH 415
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 486 RKETGQFDPdafiasglSTGNGAAPTkggydlneffvelsipvladlpgaklldfsvasrysDYSNFgnttNNKFGFRWK 565
Cdd:TIGR01786 416 YKTDPKADE--------SKDYGAISK------------------------------------TYSRW----SPSLGLTYK 447
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 566 PIDDLMIRGNYSEGFRAPSINNLYrgdtdsfetyidpcssnaglrtgavaaqcaaqgvpanfvqpgaGAGRKQTVVPFTW 645
Cdd:TIGR01786 448 PTPWLTLYYSYSQGFRAPSFDELY-------------------------------------------GTGAHPGGGPYTF 484
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 646 QANPNLKPETSTSKTLglvwspsfvtGLNVTLDWWQIKVedAITRPAIQDIMSYCYGGTPQQQAaycglitrdpnygtvN 725
Cdd:TIGR01786 485 LPNPNLKPETSKNWEI----------GINLHFDQLDFKV--SYFRNDYKDFIDLGIGVTAKGNM---------------A 537
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 726 QRYTITNVNMplQNLASYKVEGWDLGLAYRLpeTSFGQFTISWdstylsKWDTKstqdspVEGRQGRYRDQDPYWR-IRS 804
Cdd:TIGR01786 538 QVGSNTITNY--VNIDNARIRGIELSGRYDL--GSFFSGPDGW------TTTLK------YGYTKGKDSDTNPWLNaITP 601
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 805 NLYVDW-SY----GDFGVNWGLRYKSGMREEcpfdpaQDPETFPFCSDGAKGENHIA-STTYHDIQVRYNtPWKG-TIML 877
Cdd:TIGR01786 602 LKVVLGlGYdhpdEKWGVGLTLTFSGAKDAV------DAYATYYENGEAAKAGPLRTpSYTVVDLYGYYK-PNKNlTLRF 674
|
890 900 910
....*....|....*....|....*....|..
gi 896543840 878 GLNNAFDKDPPVSYSVR-ANMFDPQYDLPGRY 908
Cdd:TIGR01786 675 GVYNLLDRKYTTWESARqAGPLATGYTAPGRN 706
|
|
| btuB |
PRK10641 |
TonB-dependent vitamin B12 receptor BtuB; |
14-233 |
6.57e-22 |
|
TonB-dependent vitamin B12 receptor BtuB;
Pssm-ID: 236730 [Multi-domain] Cd Length: 614 Bit Score: 101.22 E-value: 6.57e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 14 VALVAGVASTATAQAQEATNLDRISVTGSRIKstdietsQPVLSL-------TRADIEKQGVTSVADILQRVAanGAALN 86
Cdd:PRK10641 5 ASLLTALSVTAFSGWAQDTSPDTLVVTANRFQ-------QPVSTVlapttvvTRDDIDRWQSKSVNDVLRRLP--GVDIA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 87 RtfnNGGDG-SAGVSLRNLGAERTLVLVNGRRWT-TGLDGSVDLNTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITK 164
Cdd:PRK10641 76 Q---NGGLGqLSSLFIRGTNSSHVLVLIDGVRLNqAGISGSADLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITT 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896543840 165 QNFDGAEVNAYKG-----QYSAGDGQReaydftlgtVTDRASITVGASYVNEKSVmagdrKISAGGPPFFSGQS 233
Cdd:PRK10641 153 RDKPGTTLSAGWGsngyqNYDGSTQQQ---------LGDNTRVTLAGDYTYTKGF-----DVVAYGNTGTQAQP 212
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
471-916 |
8.49e-21 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 96.76 E-value: 8.49e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 471 QLPAGALGFAAGYEYRketgQFDPDAFIASGLSTGNGAAPTKGGYDLNEFFVELSIPVLADLpgakllDFSVASRYSDYS 550
Cdd:pfam00593 132 DLLLGVELRTAGLDYR----RLDDDAYDPYDPANPSSSSYSDTTTDSYGLYLQDNIKLTDRL------TLTLGLRYDHYS 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 551 NFGNTTNN--------------KFGFRWKPIDDLMIRGNYSEGFRAPSINNLYrgdtdsfetyidpcssnaglrtgavaa 616
Cdd:pfam00593 202 TDGDDGNGggdnfsrsysafspRLGLVYKPTDNLSLYASYSRGFRAPSLGELY--------------------------- 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 617 qcaaqgvpanfvqpgagAGRKQTVVPFTWQANPNLKPETSTSKTLGLVWSPSfvtGLNVTLDWWQIKVEDaitrpaiqdi 696
Cdd:pfam00593 255 -----------------GSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDG---RLSLSLALFYIDIKN---------- 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 697 msycyggtpqqqaaycgLITRDPNYGTVNQRYTITnvnmplQNLASYKVEGWDLGLAYRLpetsfgqFTISWDSTYLSKW 776
Cdd:pfam00593 305 -----------------LITSDPDGPGLGGTVYTY------TNVGKARIRGVELELSGRL-------WGLGLSGGGYTYT 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 777 DTKSTQDspvEGRQGRYRDQDPYWRIrsNLYVDWSY--GDFGVNWGLRYkSGMREECPFDPAQDPETfpfcsdgakgenh 854
Cdd:pfam00593 355 DADDDAD---ADDTGNPLPNVPRHTA--NLGLTYDFplGGWGARLGARY-VGSGERRYGDAANTFKT------------- 415
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 896543840 855 iASTTYHDIQVRYNTPWKGTIMLGLNNAFDKDPPVSYSVRANMFDpQYDLPGRYMYMQYKQK 916
Cdd:pfam00593 416 -PGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGGGNLG-GYPGPGRTFYLGLSYK 475
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
11-395 |
1.04e-20 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 97.66 E-value: 1.04e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 11 AVLVALVAGVASTATAQAQEATNLDRISVTGSRIKSTD----------------IETSQPVLSLTRADIEKQGVTSVADI 74
Cdd:COG4773 9 GLAAAAAGALAQAAAAAAAEATTLPEVTVTGTAEGTGGytakssstatkldtplRETPQSVSVVTRQLIEDQGATTLDDA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 75 LQRVAanGAalnRTFNNGGDGSAGVSLRnlGAERTLVLVNGRRwttglDGSVDLNTIPTAMIERIDILKDGASTIYGSDA 154
Cdd:COG4773 89 LRNVP--GV---TVSSYDGGGRDSFSIR--GFSIDNYLRDGLP-----LGGFGGGQPDTANLERVEVLKGPAGLLYGAGS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 155 IAGVVNIITK--QNFDGAEVNAykgQYSAGDGQREAYDFTlGTVTDRASIT---VGA-----SYV----NEKSVMAG--- 217
Cdd:COG4773 157 PGGLVNLVTKrpTAEPQGEVSL---SAGSWDTYRATADVG-GPLNEDGTLRyrlNAAyedgdSFRdgvdNRRTLIAPsld 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 218 ----DR-KISAGGppFFSGQSATGIPGSYVRNGNQYVIingvetPFDANVhgynTAPDNYllTPNERTSLFVLGSYNVTD 292
Cdd:COG4773 233 wdltDDtTLTLGA--EYQDDDSTGDRGFLPLDGTLLDL------PRSTNL----GEPWDY--YDTETTTLFAELEHRFND 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 293 NITFRTEAMYNERKSEQLLAsmpvtgqrlsagSMYNPYGVDLTGVNRRFNESGGRSfnqnvKNWHFYGGFEGFFEFADRN 372
Cdd:COG4773 299 DWSLRANARYSDSDRDGRSA------------YAYGAPDAATGTLTRYASARDGDS-----RSDSLDANLNGKFETGGLE 361
|
410 420
....*....|....*....|....*
gi 896543840 373 FDWDVG--YRYDKTDQNDLTYGLFN 395
Cdd:COG4773 362 HTLLVGadYSRYDSDSDSATAGTIN 386
|
|
| PRK13483 |
PRK13483 |
ligand-gated channel protein; |
11-165 |
2.04e-17 |
|
ligand-gated channel protein;
Pssm-ID: 184080 [Multi-domain] Cd Length: 660 Bit Score: 87.14 E-value: 2.04e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 11 AVLVALVAGVASTATAQAQEATNLDRISVT--GSRIKSTDIETSQPVLslTRADIEKQGVTSVADILQRVAanGAALNrt 88
Cdd:PRK13483 10 SALCLLPAVFVTHALAQAAPDKTMETVVVTasGYEQQIRDAPASISVI--TREDLENRFYRDLTDALLDVP--GVVVT-- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 89 fnnGGDGSAGVSLRNLGAERTLVLVNGRRWTT----------GLDGSVdlnTIPTAMIERIDILKDGASTIYGSDAIAGV 158
Cdd:PRK13483 84 ---GGGDRTDISLRGMGSQYTLILVDGKRQSSretrpnsdgpGVEQAW---TPPLAAIERIEVIRGPMSSLYGSDAIGGV 157
|
....*..
gi 896543840 159 VNIITKQ 165
Cdd:PRK13483 158 INIITRK 164
|
|
| PRK10064 |
PRK10064 |
catecholate siderophore receptor CirA; Provisional |
12-165 |
3.31e-17 |
|
catecholate siderophore receptor CirA; Provisional
Pssm-ID: 236646 [Multi-domain] Cd Length: 663 Bit Score: 86.48 E-value: 3.31e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 12 VLVALVAGVASTATAQAQEATNLDRISVTGSRIKSTDIETSQPVLSLTRADIEKQGVTSVADILQRVAAngaalnRTFNN 91
Cdd:PRK10064 8 VRVGLCASAISCAWPVLAVDDDGETMVVTASAVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPG------VQLTN 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896543840 92 GGDGSAGVSLRNLGAERTLVLVNGRRWTTG----LDGSVDLNTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITKQ 165
Cdd:PRK10064 82 EGDNRKGVSIRGLDSSYTLILIDGKRVNSRnavfRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKK 159
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
49-395 |
2.59e-16 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 83.39 E-value: 2.59e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 49 IETSQPVLSLTRADIEKQGVTSVADILQRVAanGAALNRTFNNGGDGsagVSLRNLGAeRTLVLVNGRRWTTGldgsvdl 128
Cdd:COG4774 7 LDTPQSVTVVTRELIEDQGATSLADALRNVP--GVTFGAGEGGNGDS---FSIRGFSA-SGDIYVDGLRDPGQ------- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 129 NTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITKQNFDGAEVNAYkGQYSAGDGQREAYDFTlGTVTDRASITVGASY 208
Cdd:COG4774 74 YRRDTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRPTDEPFTEVT-LTYGSDGQRRATLDVN-GPLGDDLAYRLNGMY 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 209 VNEKS-VMAGDRKISAGGPPF-FSGQSATGIPGSYVRNGNQYVIINGVetPFDANVHGYNTAPDNYLLTPN-----ERTS 281
Cdd:COG4774 152 RDSDSyRDGVDNDRWGIAPSLtWRLGDRTRLTLDYEYQDDDRTPDYGV--PAVANGRPVDVDRSTFYGQPDdysdsETDS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 282 LFVLGSYNVTDNITFRTEAMYNERKSEQLLAsmpvtgqrlsagsmyNPYGVDLTGVNRRfnesGGRSFNQNVKNWHFYGG 361
Cdd:COG4774 230 ATLRLEHDFNDNWTLRNALRYSDYDRDYRNT---------------YPTGGNATGTVTR----SAYRRDQDNDTLSNQTD 290
|
330 340 350
....*....|....*....|....*....|....
gi 896543840 362 FEGFFEFADRNFDWDVGYRYDKTDQNDLTYGLFN 395
Cdd:COG4774 291 LTGKFDTGGVKHTLLAGVEYSREDSDNARYSGGG 324
|
|
| PRK13513 |
PRK13513 |
ligand-gated channel protein; |
6-165 |
5.22e-15 |
|
ligand-gated channel protein;
Pssm-ID: 184104 [Multi-domain] Cd Length: 659 Bit Score: 79.43 E-value: 5.22e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 6 NKLRDAVLVALVAGVASTATAQAQEATNLDRISVTGSRIKSTdIETSQPVLS-LTRADIEKQGVTSVADILQRVAanGAA 84
Cdd:PRK13513 7 KTHKAALVIAAAISSQAYAAEKTNTATPTDTMVVTASGFQQR-IQDAPASISvVTREQLENKAYRDVTDALKDVP--GVV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 85 LNrtfnnGGDGSAGVSLRNLGAERTLVLVNGRRWTT-GLDGSVDLNTI------PTAMIERIDILKDGASTIYGSDAIAG 157
Cdd:PRK13513 84 VT-----GGGSTSDISIRGMAAKYTLILVDGKRVDTrSTRPNSDGSGIeqgwlpPLAAIERIEVVRGPMSSLYGSDAMGG 158
|
....*...
gi 896543840 158 VVNIITKQ 165
Cdd:PRK13513 159 VINIITRK 166
|
|
| PRK13484 |
PRK13484 |
IreA family TonB-dependent siderophore receptor; |
13-170 |
2.25e-14 |
|
IreA family TonB-dependent siderophore receptor;
Pssm-ID: 139605 [Multi-domain] Cd Length: 682 Bit Score: 77.35 E-value: 2.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 13 LVALVAGVASTATAQAQEatNLDRISVTGSRIKSTDIETSQPVLSLTRADIEKQGVTSVADILQRVaaNGAALNrtfnnG 92
Cdd:PRK13484 11 IAVMCSAVISSGYASSDK--KEDTLVVTASGFTQQLRNAPASVSVITSEQLQKKPVSDLVDAVKDV--EGISIT-----G 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 93 GDGSAGVSLRNLGAERTLVLVNGRRWTT-----GLDGSVDLNTIPTA-MIERIDILKDGASTIYGSDAIAGVVNIITK-- 164
Cdd:PRK13484 82 GNEKPDISIRGLSGDYTLILVDGRRQSGresrpNGSGGFEAGFIPPVeAIERIEVIRGPMSSLYGSDAIGGVINIITKpv 161
|
....*...
gi 896543840 165 --QNFDGA 170
Cdd:PRK13484 162 nnQTWDGV 169
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
16-391 |
4.25e-14 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 76.51 E-value: 4.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 16 LVAGVASTATAQAQEA-TNLDRISVTGSRIKSTDIETsQP--VLSLTRADIEKQGVTSVADILQRVA------ANGAALn 86
Cdd:COG4772 4 ALAAALLLAAAAAAEAaTTLETVVVTGSRAAEARLKD-VPgsVSVVDREELENQAATSLREVLRRVPgvnvqeEDGFGL- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 87 rtfnnggdgSAGVSLRNLGAERT---LVLVNGRRWTTGL--DGSVDLNTIPTAMiERIDILKDGASTIYGSDAIAGVVNI 161
Cdd:COG4772 82 ---------RPNIGIRGLGPRRSrgiTLLEDGIPIAPAPygDPAAYYFPDLERM-ERIEVLRGAAALRYGPQTVGGAINF 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 162 ITKQ--NFDGAEVNAYKGQYSAGDGQreaydFTLGTVTDRASITVGASYVNeksvMAGDRKISA---------GGPPFFS 230
Cdd:COG4772 152 VTRTipTAFGGELRVTGGSFGYRRTH-----ASVGGTVGNFGYLVEYSRKR----GDGFRDNSGfdindfnakLGYRLSD 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 231 GQSATGIPGSYVRNGNQYviinGVETPFDANVHGY-NTAPDNYLLTpnERTSLFVLGSYNVTDNITFRTEAMYNERKseq 309
Cdd:COG4772 223 RQELTLKFQYYDEDANTP----GGLTDAQFDADPRqSYRPADQFDT--RRTQLSLRYEHQLSDNTTLTTTAYYNDFS--- 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 310 llasmpVTGQRLSAGSMYNPYGVDLTGVNRRFNESGGRSfnqnvkNWHFYggfegfFEFADRNFDWDVGYRYDKTDQNDL 389
Cdd:COG4772 294 ------RNWYIRQNTADPNTPGLGLRGNPRGYRSYGIEP------RLTHR------FELGGVPHTLEVGLRYHREEEDRK 355
|
..
gi 896543840 390 TY 391
Cdd:COG4772 356 QY 357
|
|
| PRK13524 |
PRK13524 |
FepA family TonB-dependent siderophore receptor; |
11-254 |
1.75e-13 |
|
FepA family TonB-dependent siderophore receptor;
Pssm-ID: 237410 [Multi-domain] Cd Length: 744 Bit Score: 74.68 E-value: 1.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 11 AVLVAL------VAGVASTATAQAQEATNLDRISVTGSRikstdiETSQ-PVLS-LTRADIEKQGVTS-VADILQRVAAn 81
Cdd:PRK13524 9 ALLVNLgiygvaQAAEAEDAKTDDTPASHEDTIVVTAAE------QNLQaPGVStITAEDIRKRPPANdVSEIIRTMPG- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 82 gaaLNRTfNNGGDGSAG----VSLRNLGAERTLVLVNGRR----------WTTGLDGSVDLNTIPTAMIERIDILKDGAS 147
Cdd:PRK13524 82 ---VNLT-GNSTSGQRGnnrqIDIRGMGPENTLILIDGKPvssrnsvrygWRGERDTRGDTNWVPPEMIERIEVLRGPAA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 148 TIYGSDAIAGVVNIITKQNFDGAE--VNAYKG--QYSA-GDGQReaYDFTL-GTVTDRASITVgasYVNEKSVMAGDRKI 221
Cdd:PRK13524 158 ARYGNGAAGGVVNIITKKPTGEWHgsWNTYFNapEHKAeGATKR--TNFSLsGPLGDELSFRL---YGNLNKTQADAWDI 232
|
250 260 270
....*....|....*....|....*....|....*
gi 896543840 222 SAGGPPFFSGQSATGIPGSY--VRNGNqyviINGV 254
Cdd:PRK13524 233 NQGHQSARTGSYAGTLPAGRegVINKD----INGL 263
|
|
| PRK13528 |
PRK13528 |
outer membrane receptor FepA; Provisional |
6-165 |
6.24e-13 |
|
outer membrane receptor FepA; Provisional
Pssm-ID: 237413 [Multi-domain] Cd Length: 727 Bit Score: 72.87 E-value: 6.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 6 NKLRDAVLVALVAGVASTATAQAQEATNLDRISVTGS---RIKStdietsQPVLSL-TRADIEKQG-VTSVADILQRVAA 80
Cdd:PRK13528 6 NKILWLLTVLLVGLNSPVSAAESSDDDNGETMVVEATaeqELKQ------QPGVSIiTAEDIKKRPpVNDLSDIIRKMPG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 81 ngaaLNRTfNNGGDGSAG----VSLRNLGAERTLVLVNGR----------RWTTGLDGSVDLNTIPTAMIERIDILKDGA 146
Cdd:PRK13528 80 ----VNLT-GNSASGTRGnnrqIDIRGMGPENTLILIDGVpvtsrnsvrySWRGERDTRGDTNWVPPEMVERIEVIRGPA 154
|
170
....*....|....*....
gi 896543840 147 STIYGSDAIAGVVNIITKQ 165
Cdd:PRK13528 155 AARYGSGAAGGVVNIITKR 173
|
|
| PRK13486 |
PRK13486 |
TonB-dependent receptor; |
8-168 |
5.10e-12 |
|
TonB-dependent receptor;
Pssm-ID: 139606 [Multi-domain] Cd Length: 696 Bit Score: 69.67 E-value: 5.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 8 LRDAVLVALVAGVASTATAQAQEATNLDRISVTGSRIKSTDIETSQPVLSltRADIEKQGVTSVADILQRVAAngaaLNR 87
Cdd:PRK13486 1 MRITTLASVVIPCLGFSASSIAAAEDVMIVSASGYEKKLTNAAASVSVIS--QEELQSSQYHDLAEALRSVEG----VDV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 88 TFNNGGDGSAGVSLRNLGAERTLVLVNGRRWTTGLD----GSVDLNT---IPTAMIERIDILKDGASTIYGSDAIAGVVN 160
Cdd:PRK13486 75 ESGTGKTGGLEISIRGMPASYTLILIDGVRQGGSSDvtpnGFSAMNTgfmPPLAAIERIEVIRGPMSTLYGSDAMGGVVN 154
|
....*...
gi 896543840 161 IITKQNFD 168
Cdd:PRK13486 155 IITRKNAD 162
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
50-165 |
8.08e-12 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 68.98 E-value: 8.08e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 50 ETSQPVLSLTRADIEKQGVTSVADILQRVAAngaaLNRTFNNGGDGSAGVSLRNLGAERTL--VLVNGRRwttgLDGSVD 127
Cdd:TIGR01783 1 DIPQSVSVITRQELEDQQAGSLSEALQRVPG----VVVGGSGGTTQFGNITIRGFGLEVDIdnVYLDGVP----LLSRGN 72
|
90 100 110
....*....|....*....|....*....|....*...
gi 896543840 128 LNTIPTAMIERIDILKDGASTIYGSDAIAGVVNIITKQ 165
Cdd:TIGR01783 73 LAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKR 110
|
|
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
36-165 |
1.64e-07 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 55.29 E-value: 1.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 36 RISVTGSrikstdietsqpVLSLTRADIEKQGVTSVADILQ-RVAAngaaLNRTFNNGGDG-SAGVSLR---NLGAERT- 109
Cdd:TIGR04056 91 KKSLTGA------------VSTVKAKELKKVPVSNLSNALQgKVAG----VIITQSSGEPGgDAEIWIRgisSFGGNNSp 154
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 896543840 110 LVLVNGrrwttgLDGSVDLNTIPTAMIERIDILKDGAST-IYGSDAIAGVVNIITKQ 165
Cdd:TIGR04056 155 LYVIDG------VPRDNGLSDLNPEDIESISVLKDASATaIYGSRGANGVILITTKR 205
|
|
| PRK09840 |
PRK09840 |
catecholate siderophore receptor Fiu; Provisional |
11-184 |
2.32e-06 |
|
catecholate siderophore receptor Fiu; Provisional
Pssm-ID: 182105 [Multi-domain] Cd Length: 761 Bit Score: 51.35 E-value: 2.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 11 AVLVALVAGVASTATAQAQE-ATNLDRISVTG----SRIK---STDIETSQPVLSLTR-------ADIEKQGVTSVADIL 75
Cdd:PRK09840 16 AFFAGLCIGITPVAQALAAEgQTNADDTLVVEastpSLYApdqSADPKFSQPLADTTQtitviseQVIKDQGATNLTEAL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 76 QRVAANGaalnrTFNNGGDGSA----GVSLRNLGAERTLVLvngrrwttglDGSVDLNTIPTAM--IERIDILKDGASTI 149
Cdd:PRK09840 96 RNVPGVG-----TFFAGENGNTttgdAIYMRGFDTSNSIYV----------DGIRDIGSISRDTfnTEQVEVIKGPSGTD 160
|
170 180 190
....*....|....*....|....*....|....*
gi 896543840 150 YGSDAIAGVVNIITKQNFDGaevNAYKGQYSAGDG 184
Cdd:PRK09840 161 YGRSAPTGSINMISKQPRND---SGIDASASIGSA 192
|
|
| PRK14050 |
PRK14050 |
TonB-dependent siderophore receptor; |
20-168 |
1.04e-04 |
|
TonB-dependent siderophore receptor;
Pssm-ID: 237595 [Multi-domain] Cd Length: 728 Bit Score: 45.95 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 20 VASTATAQAQEATNLDRISV-----------------------TGSRIKSTDIETSQPVLSLTRADIEKQGVTSVADILQ 76
Cdd:PRK14050 25 LSGLVAAQEGNTTQLETIVVeggnaasatatgpvdgyvakataTGSKTDTPITEIPQSVSVVGRQEMDDRGVTNKVDEAL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896543840 77 RVAAngAALNRTFNNGGDgSAGVSLRNLGAERTLVLVNG-RRWTTGLDGSVdlntIPTAMIERIDILKDGASTIYGSDAI 155
Cdd:PRK14050 105 RYTP--GVLSQPFGTDGD-TDWFYIRGFDATQTGVFLDGlNLFSYGFGGFQ----IDPFMLERVEVLKGPASVLYGGSNP 177
|
170
....*....|...
gi 896543840 156 AGVVNIITKQNFD 168
Cdd:PRK14050 178 GGIVNMVSKRPLD 190
|
|
| SusC_RagA_signa |
TIGR04057 |
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ... |
136-164 |
4.04e-04 |
|
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.
Pssm-ID: 274949 [Multi-domain] Cd Length: 31 Bit Score: 38.33 E-value: 4.04e-04
10 20 30
....*....|....*....|....*....|
gi 896543840 136 IERIDILKDGAST-IYGSDAIAGVVNIITK 164
Cdd:TIGR04057 2 IESISVLKDASAAaIYGSRGANGVILITTK 31
|
|
| |
