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Conserved domains on  [gi|896554602|ref|WP_049454814|]
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MULTISPECIES: glycosyltransferase family 2 protein [Stenotrophomonas]

Protein Classification

glycosyltransferase family 2 protein( domain architecture ID 10135931)

glycosyltransferase family 2 protein catalyzes the transfer of saccharide moieties from a donor to an acceptor to form glycosidic bonds

CATH:  3.90.550.10
CAZY:  GT2
EC:  2.4.-.-
Gene Ontology:  GO:0016757|GO:0006486
PubMed:  10508766|12200473|9445404|12691742|10521532
SCOP:  3000077

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GT_2_like_d cd04196
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 9-231 1.17e-73

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


:

Pssm-ID: 133039 [Multi-domain]  Cd Length: 214  Bit Score: 226.36  E-value: 1.17e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   9 SVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQEVATLHARgieVVLRRQQQNVGYVRNFESALLQ 88
Cdd:cd04196    1 AVLMATYNGEKYLREQLDSILAQTYKNDELIISDDGSTDGTVEIIKEYIDKDPFI---IILIRNGKNLGVARNFESLLQA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  89 CSGDIVFLCDQDDLWREDKIETFLRIFDARPGLRLLHSNAQLVDAEGVPLRATLFQALAIDrqdikrehRGEGFEVLLGR 168
Cdd:cd04196   78 ADGDYVFFCDQDDIWLPDKLERLLKAFLKDDKPLLVYSDLELVDENGNPIGESFFEYQKIK--------PGTSFNNLLFQ 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896554602 169 NIVTGAVTALRRDLIAEALPVADG--WIHDEWLAMVAAASGGLDCIETITTDYRQHDRNQVGAHR 231
Cdd:cd04196  150 NVVTGCTMAFNRELLELALPFPDAdvIMHDWWLALLASAFGKVVFLDEPLILYRQHGNNVVGANK 214
 
Name Accession Description Interval E-value
GT_2_like_d cd04196
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 9-231 1.17e-73

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133039 [Multi-domain]  Cd Length: 214  Bit Score: 226.36  E-value: 1.17e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   9 SVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQEVATLHARgieVVLRRQQQNVGYVRNFESALLQ 88
Cdd:cd04196    1 AVLMATYNGEKYLREQLDSILAQTYKNDELIISDDGSTDGTVEIIKEYIDKDPFI---IILIRNGKNLGVARNFESLLQA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  89 CSGDIVFLCDQDDLWREDKIETFLRIFDARPGLRLLHSNAQLVDAEGVPLRATLFQALAIDrqdikrehRGEGFEVLLGR 168
Cdd:cd04196   78 ADGDYVFFCDQDDIWLPDKLERLLKAFLKDDKPLLVYSDLELVDENGNPIGESFFEYQKIK--------PGTSFNNLLFQ 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896554602 169 NIVTGAVTALRRDLIAEALPVADG--WIHDEWLAMVAAASGGLDCIETITTDYRQHDRNQVGAHR 231
Cdd:cd04196  150 NVVTGCTMAFNRELLELALPFPDAdvIMHDWWLALLASAFGKVVFLDEPLILYRQHGNNVVGANK 214
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 5-223 1.07e-24

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 99.01  E-value: 1.07e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   5 TTTVSVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQevatLHARGIEVVLRRQQQNVGYVRNFES 84
Cdd:COG0463    1 MPLVSVVIPTYNEEEYLEEALESLLAQTYPDFEIIVVDDGSTDGTAEILRE----LAAKDPRIRVIRLERNRGKGAARNA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  85 ALLQCSGDIVFLCDQDDLWREDKIETFLRIFDARPGLRLLHSnaQLVDAEGVPLRATLFQALAIDRqdikrehrgegfeV 164
Cdd:COG0463   77 GLAAARGDYIAFLDADDQLDPEKLEELVAALEEGPADLVYGS--RLIREGESDLRRLGSRLFNLVR-------------L 141

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 896554602 165 LLGRNIVTGAVTALRRDLIaEALPVADGWIHDewLAMVAAASGGLDCIEtITTDYRQHD 223
Cdd:COG0463  142 LTNLPDSTSGFRLFRREVL-EELGFDEGFLED--TELLRALRHGFRIAE-VPVRYRAGE 196
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 9-117 6.25e-16

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 74.35  E-value: 6.25e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602    9 SVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQevatLHARGIEVVLRRQQQNVGYVRNFESALLQ 88
Cdd:pfam00535   1 SVIIPTYNEEKYLLETLESLLNQTYPNFEIIVVDDGSTDGTVEIAEE----YAKKDPRVRVIRLPENRGKAGARNAGLRA 76

                          90       100
                  ....*....|....*....|....*....
gi 896554602   89 CSGDIVFLCDQDDLWREDKIETFLRIFDA 117
Cdd:pfam00535  77 ATGDYIAFLDADDEVPPDWLEKLVEALEE 105
PRK10073 PRK10073
putative glycosyl transferase; Provisional
 1-114 9.75e-05

putative glycosyl transferase; Provisional


Pssm-ID: 182223 [Multi-domain]  Cd Length: 328  Bit Score: 43.50  E-value: 9.75e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   1 MSSVTTTVSVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQEVATL-HARgievVLRRQQQNVGYV 79
Cdd:PRK10073   1 MMNSTPKLSIIIPLYNAGKDFRAFMESLIAQTWTALEIIIVNDGSTDNSVEIAKHYAENYpHVR----LLHQANAGVSVA 76

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 896554602  80 RNfeSALLQCSGDIVFLCDQDDLWREDKIETFLRI 114
Cdd:PRK10073  77 RN--TGLAVATGKYVAFPDADDVVYPTMYETLMTM 109
 
Name Accession Description Interval E-value
GT_2_like_d cd04196
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 9-231 1.17e-73

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133039 [Multi-domain]  Cd Length: 214  Bit Score: 226.36  E-value: 1.17e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   9 SVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQEVATLHARgieVVLRRQQQNVGYVRNFESALLQ 88
Cdd:cd04196    1 AVLMATYNGEKYLREQLDSILAQTYKNDELIISDDGSTDGTVEIIKEYIDKDPFI---IILIRNGKNLGVARNFESLLQA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  89 CSGDIVFLCDQDDLWREDKIETFLRIFDARPGLRLLHSNAQLVDAEGVPLRATLFQALAIDrqdikrehRGEGFEVLLGR 168
Cdd:cd04196   78 ADGDYVFFCDQDDIWLPDKLERLLKAFLKDDKPLLVYSDLELVDENGNPIGESFFEYQKIK--------PGTSFNNLLFQ 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896554602 169 NIVTGAVTALRRDLIAEALPVADG--WIHDEWLAMVAAASGGLDCIETITTDYRQHDRNQVGAHR 231
Cdd:cd04196  150 NVVTGCTMAFNRELLELALPFPDAdvIMHDWWLALLASAFGKVVFLDEPLILYRQHGNNVVGANK 214
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 5-223 1.07e-24

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 99.01  E-value: 1.07e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   5 TTTVSVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQevatLHARGIEVVLRRQQQNVGYVRNFES 84
Cdd:COG0463    1 MPLVSVVIPTYNEEEYLEEALESLLAQTYPDFEIIVVDDGSTDGTAEILRE----LAAKDPRIRVIRLERNRGKGAARNA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  85 ALLQCSGDIVFLCDQDDLWREDKIETFLRIFDARPGLRLLHSnaQLVDAEGVPLRATLFQALAIDRqdikrehrgegfeV 164
Cdd:COG0463   77 GLAAARGDYIAFLDADDQLDPEKLEELVAALEEGPADLVYGS--RLIREGESDLRRLGSRLFNLVR-------------L 141

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 896554602 165 LLGRNIVTGAVTALRRDLIaEALPVADGWIHDewLAMVAAASGGLDCIEtITTDYRQHD 223
Cdd:COG0463  142 LTNLPDSTSGFRLFRREVL-EELGFDEGFLED--TELLRALRHGFRIAE-VPVRYRAGE 196
Glyco_tranf_GTA_type cd00761
Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a ...
 10-165 4.12e-17

Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.


Pssm-ID: 132997 [Multi-domain]  Cd Length: 156  Bit Score: 77.16  E-value: 4.12e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  10 VALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQevatLHARGIEVVLRRQQQNVGYVRNFESALLQC 89
Cdd:cd00761    1 VIIPAYNEEPYLERCLESLLAQTYPNFEVIVVDDGSTDGTLEILEE----YAKKDPRVIRVINEENQGLAAARNAGLKAA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  90 SGDIVFLCDQDDLWREDKIETFLRIFDARPGLRLLHSNAQLV----DAEGVPLRATLFQALAIDRQDIKREHRGEGFEVL 165
Cdd:cd00761   77 RGEYILFLDADDLLLPDWLERLVAELLADPEADAVGGPGNLLfrreLLEEIGGFDEALLSGEEDDDFLLRLLRGGKVAFR 156
WcaE COG1216
Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];
7-113 2.06e-16

Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism];


Pssm-ID: 440829 [Multi-domain]  Cd Length: 202  Bit Score: 76.57  E-value: 2.06e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   7 TVSVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTwgvlEQEVATLHARGIEVVlrRQQQNVGYVRNFESAL 86
Cdd:COG1216    4 KVSVVIPTYNRPELLRRCLESLLAQTYPPFEVIVVDNGSTDGT----AELLAALAFPRVRVI--RNPENLGFAAARNLGL 77

                         90       100
                 ....*....|....*....|....*..
gi 896554602  87 LQCSGDIVFLCDQDDLWREDKIETFLR 113
Cdd:COG1216   78 RAAGGDYLLFLDDDTVVEPDWLERLLA 104
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 9-117 6.25e-16

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 74.35  E-value: 6.25e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602    9 SVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQevatLHARGIEVVLRRQQQNVGYVRNFESALLQ 88
Cdd:pfam00535   1 SVIIPTYNEEKYLLETLESLLNQTYPNFEIIVVDDGSTDGTVEIAEE----YAKKDPRVRVIRLPENRGKAGARNAGLRA 76

                          90       100
                  ....*....|....*....|....*....
gi 896554602   89 CSGDIVFLCDQDDLWREDKIETFLRIFDA 117
Cdd:pfam00535  77 ATGDYIAFLDADDEVPPDWLEKLVEALEE 105
CESA_like_1 cd06439
CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of ...
 5-207 8.10e-10

CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of cellulose synthase (CESA) superfamily. CESA superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members of the superfamily include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins.


Pssm-ID: 133061 [Multi-domain]  Cd Length: 251  Bit Score: 58.36  E-value: 8.10e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   5 TTTVSVALCTWQGERYIAAQLRTVGAQTvLPT---QVVIVDDASTDGTwgvleQEVATLHARGIeVVLRRQQQNVGYVRN 81
Cdd:cd06439   28 LPTVTIIIPAYNEEAVIEAKLENLLALD-YPRdrlEIIVVSDGSTDGT-----AEIAREYADKG-VKLLRFPERRGKAAA 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  82 FESALLQCSGDIVFLCDQDDLWREDKIETFLRIFdARPGLRLLHSNAQLVDAEGVPlratlfqalaidrqdikrehRGEG 161
Cdd:cd06439  101 LNRALALATGEIVVFTDANALLDPDALRLLVRHF-ADPSVGAVSGELVIVDGGGSG--------------------SGEG 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 896554602 162 F-----------EVLLGRNI-VTGAVTALRRDLIAEalPVADGWIHDEWLAMVAAASG 207
Cdd:cd06439  160 LywkyenwlkraESRLGSTVgANGAIYAIRRELFRP--LPADTINDDFVLPLRIARQG 215
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 7-128 3.41e-09

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 57.06  E-value: 3.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   7 TVSVALCTWQGERYIAAQLRTVGAQTVLPT--QVVIVDDASTDGTWGVLEQevatLHARGIEVVLRRQQQNVGYVRNFES 84
Cdd:COG1215   30 RVSVIIPAYNEEAVIEETLRSLLAQDYPKEklEVIVVDDGSTDETAEIARE----LAAEYPRVRVIERPENGGKAAALNA 105

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 896554602  85 ALLQCSGDIVFLCDQDDLWREDKIETFLRIFdARPGLRLLHSNA 128
Cdd:COG1215  106 GLKAARGDIVVFLDADTVLDPDWLRRLVAAF-ADPGVGASGANL 148
GT2_AmsE_like cd04195
GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis; AmsE is a ...
 9-138 5.56e-08

GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis; AmsE is a glycosyltransferase involved in exopolysaccharide amylovora biosynthesis in Erwinia amylovora. Amylovara is one of the three exopolysaccharide produced by E. amylovora. Amylovara-deficient mutants are non-pathogenic. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133038 [Multi-domain]  Cd Length: 201  Bit Score: 52.32  E-value: 5.56e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   9 SVALCTWQGER--YIAAQLRTVGAQTVLPTQVVIVDDastdgtwGVLEQ---EVATLHARGIEVVLRRQQQNVGYVRNFE 83
Cdd:cd04195    1 SVLMSVYIKEKpeFLREALESILKQTLPPDEVVLVKD-------GPVTQslnEVLEEFKRKLPLKVVPLEKNRGLGKALN 73

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 896554602  84 SALLQCSGDIVFLCDQDDLWREDKIETFLRIFDARPGLRLLHSNAQLVDAEGVPL 138
Cdd:cd04195   74 EGLKHCTYDWVARMDTDDISLPDRFEKQLDFIEKNPEIDIVGGGVLEFDSDGNDI 128
DPM_DPG-synthase_like cd04179
DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the ...
 38-101 2.08e-07

DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133022 [Multi-domain]  Cd Length: 185  Bit Score: 50.26  E-value: 2.08e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 896554602  38 VVIVDDASTDGTWGVLEQevatLHARGIEVVLRRQQQNVGYVRNFESALLQCSGDIVFLCD---QDD 101
Cdd:cd04179   31 IIVVDDGSTDGTAEIARE----LAARVPRVRVIRLSRNFGKGAAVRAGFKAARGDIVVTMDadlQHP 93
CESA_like cd06423
CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily ...
 21-196 5.63e-07

CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.


Pssm-ID: 133045 [Multi-domain]  Cd Length: 180  Bit Score: 49.15  E-value: 5.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  21 IAAQLRTVGAQTVLPTQVVIVDDASTDGTwgvLEQEVATLHARGIEVVLRRQQQNVGYVRNFESALLQCSGDIVFLCDQD 100
Cdd:cd06423   12 IERTIESLLALDYPKLEVIVVDDGSTDDT---LEILEELAALYIRRVLVVRDKENGGKAGALNAGLRHAKGDIVVVLDAD 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602 101 DLWREDKIETFLRIFDARPGLRLLHSNAQLVDAEGVPLraTLFQALAIDR-QDIkrEHRGEGfevLLGR-NIVTGAVTAL 178
Cdd:cd06423   89 TILEPDALKRLVVPFFADPKVGAVQGRVRVRNGSENLL--TRLQAIEYLSiFRL--GRRAQS---ALGGvLVLSGAFGAF 161

                        170
                 ....*....|....*...
gi 896554602 179 RRDLIAEalpvADGWIHD 196
Cdd:cd06423  162 RREALRE----VGGWDED 175
GT_2_like_c cd04186
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 10-119 3.96e-06

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133029 [Multi-domain]  Cd Length: 166  Bit Score: 46.40  E-value: 3.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  10 VALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQEVAtlhargiEVVLRRQQQNVGYVRNFESALLQC 89
Cdd:cd04186    1 IIIVNYNSLEYLKACLDSLLAQTYPDFEVIVVDNASTDGSVELLRELFP-------EVRLIRNGENLGFGAGNNQGIREA 73

                         90       100       110
                 ....*....|....*....|....*....|
gi 896554602  90 SGDIVFLCDQDDLWREDKIETFLRIFDARP 119
Cdd:cd04186   74 KGDYVLLLNPDTVVEPGALLELLDAAEQDP 103
Glyco_tranf_2_3 pfam13641
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 7-194 5.32e-06

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433372 [Multi-domain]  Cd Length: 230  Bit Score: 46.98  E-value: 5.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602    7 TVSVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQEVATLHARGIEVVlrRQQQNVGY---VRNFE 83
Cdd:pfam13641   3 DVSVVVPAFNEDSVLGRVLEAILAQPYPPVEVVVVVNPSDAETLDVAEEIAARFPDVRLRVI--RNARLLGPtgkSRGLN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   84 SALLQCSGDIVFLCDQDDLWREDKIETFLRIFDARPglrllhsnaqlVDAEGVPLRATLFQALAIDRQDIKREHRgeGFE 163
Cdd:pfam13641  81 HGFRAVKSDLVVLHDDDSVLHPGTLKKYVQYFDSPK-----------VGAVGTPVFSLNRSTMLSALGALEFALR--HLR 147

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 896554602  164 VLLGRN-----IVTGAVTALRRDLIAE------ALPVADGWI 194
Cdd:pfam13641 148 MMSLRLalgvlPLSGAGSAIRREVLKElglfdpFFLLGDDKS 189
DPM1_like_bac cd04187
Bacterial DPM1_like enzymes are related to eukaryotic DPM1; A family of bacterial enzymes ...
 23-118 6.08e-06

Bacterial DPM1_like enzymes are related to eukaryotic DPM1; A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133030 [Multi-domain]  Cd Length: 181  Bit Score: 45.93  E-value: 6.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  23 AQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQEVATL-HARGIevVLRRqqqNVGYVRNFESALLQCSGDIVFLCD--- 98
Cdd:cd04187   17 ERLKAVLESLGYDYEIIFVDDGSTDRTLEILRELAARDpRVKVI--RLSR---NFGQQAALLAGLDHARGDAVITMDadl 91

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 896554602  99 QDDL-------------------WREDKIETFLRIFDAR 118
Cdd:cd04187   92 QDPPelipemlakweegydvvygVRKNRKESWLKRLTSK 130
GT_2_like_b cd04185
Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse ...
 28-113 1.84e-05

Subfamily of Glycosyltransferase Family GT2 of unknown function; GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.


Pssm-ID: 133028 [Multi-domain]  Cd Length: 202  Bit Score: 44.93  E-value: 1.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  28 VGAQTVLPTQVVIVDDASTDGTWGVLEQevatLHARgIEVVLRRQQQNVGYVRNFESAL---LQCSGDIVFLCDQDDLWR 104
Cdd:cd04185   19 LLAQTRPPDHIIVIDNASTDGTAEWLTS----LGDL-DNIVYLRLPENLGGAGGFYEGVrraYELGYDWIWLMDDDAIPD 93


                 ....*....
gi 896554602 105 EDKIETFLR 113
Cdd:cd04185   94 PDALEKLLA 102
beta3GnTL1_like cd06913
Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of ...
 17-109 2.57e-05

Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine ; This family includes human Beta3GnTL1 and related eukaryotic proteins. Human Beta3GnTL1 is a putative beta-1,3-N-acetylglucosaminyltransferase. Beta3GnTL1 is expressed at various levels in most of tissues examined. Beta 1, 3-N-acetylglucosaminyltransferase has been found to be essential for the formation of poly-N-acetyllactosamine. Poly-N-acetyllactosamine is a unique carbohydrate composed of N-acetyllactosamine repeats. It is often an important part of cell-type-specific oligosaccharide structures and some functional oligosaccharides. It has been shown that the structure and biosynthesis of poly-N-acetyllactosamine display a dramatic change during development and oncogenesis. Several members of beta-1, 3-N-acetylglucosaminyltransferase have been identified.


Pssm-ID: 133063 [Multi-domain]  Cd Length: 219  Bit Score: 44.76  E-value: 2.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  17 GERYIAAQLRTVGAQTVL-PTQVVIVDDASTDGTWGVLEQEVATLHARGIEVVLRR----QQQNVGYVRNfeSALLQCSG 91
Cdd:cd06913    8 GEQWLDECLESVLQQDFEgTLELSVFNDASTDKSAEIIEKWRKKLEDSGVIVLVGShnspSPKGVGYAKN--QAIAQSSG 85

                         90       100
                 ....*....|....*....|
gi 896554602  92 DivFLC--DQDDLWREDKIE 109
Cdd:cd06913   86 R--YLCflDSDDVMMPQRIR 103
GT2_RfbC_Mx_like cd04184
Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene ...
 18-136 3.87e-05

Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis; The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.


Pssm-ID: 133027 [Multi-domain]  Cd Length: 202  Bit Score: 43.73  E-value: 3.87e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  18 ERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQEVATLHARgIEVVLRRQqqNVGYVRNFESALLQCSGDIVFLC 97
Cdd:cd04184   14 EKYLREAIESVRAQTYPNWELCIADDASTDPEVKRVLKKYAAQDPR-IKVVFREE--NGGISAATNSALELATGEFVALL 90

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 896554602  98 DQDDLWREDKIETFLRIFDARPGLRLLHSNAQLVDAEGV 136
Cdd:cd04184   91 DHDDELAPHALYEVVKALNEHPDADLIYSDEDKIDEGGK 129
PRK10073 PRK10073
putative glycosyl transferase; Provisional
 1-114 9.75e-05

putative glycosyl transferase; Provisional


Pssm-ID: 182223 [Multi-domain]  Cd Length: 328  Bit Score: 43.50  E-value: 9.75e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   1 MSSVTTTVSVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTDGTWGVLEQEVATL-HARgievVLRRQQQNVGYV 79
Cdd:PRK10073   1 MMNSTPKLSIIIPLYNAGKDFRAFMESLIAQTWTALEIIIVNDGSTDNSVEIAKHYAENYpHVR----LLHQANAGVSVA 76

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 896554602  80 RNfeSALLQCSGDIVFLCDQDDLWREDKIETFLRI 114
Cdd:PRK10073  77 RN--TGLAVATGKYVAFPDADDVVYPTMYETLMTM 109
PRK10018 PRK10018
colanic acid biosynthesis glycosyltransferase WcaA;
8-112 1.13e-04

colanic acid biosynthesis glycosyltransferase WcaA;


Pssm-ID: 182197 [Multi-domain]  Cd Length: 279  Bit Score: 43.06  E-value: 1.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   8 VSVALCTWQGERYIAAQLRTVGAQTVLPTQVVIVDDASTdgTWGVLEQEVATLHARGIEVVLRRQQQNVGYVRNfeSALL 87
Cdd:PRK10018   7 ISIYMPTWNRQQLAIRAIKSVLRQDYSNWEMIIVDDCST--SWEQLQQYVTALNDPRITYIHNDINSGACAVRN--QAIM 82

                         90       100
                 ....*....|....*....|....*
gi 896554602  88 QCSGDIVFLCDQDDLWREDKIETFL 112
Cdd:PRK10018  83 LAQGEYITGIDDDDEWTPNRLSVFL 107
Glyco_tranf_2_2 pfam10111
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 9-114 7.11e-04

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 313356 [Multi-domain]  Cd Length: 276  Bit Score: 40.72  E-value: 7.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602    9 SVALCTWQGER--YIAAQLRTVGAQTVLPTQVVIVDDASTDGTwgvlEQEVATLHARGIEVVLRRQQQNV---GYVRNFE 83
Cdd:pfam10111   1 SVVIPVYNGEKthWIQERILNQTFQYDPEFELIIINDGSTDKT----LEEVSSIKDHNLQVYYPNAPDTTyslAASRNRG 76

                          90       100       110
                  ....*....|....*....|....*....|.
gi 896554602   84 SAllQCSGDIVFLCDQDDLWREDKIETFLRI 114
Cdd:pfam10111  77 TS--HAIGEYISFIDGDCLWSPDKFEKQLKI 105
Beta4Glucosyltransferase cd02511
UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of ...
 37-105 1.55e-03

UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.


Pssm-ID: 133005 [Multi-domain]  Cd Length: 229  Bit Score: 39.19  E-value: 1.55e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896554602  37 QVVIVDDASTDGTwgvleQEVATlhARGIEVVlRRQQQNVGYVRNFesALLQCSGDIVFLCDQD-----DLWRE 105
Cdd:cd02511   28 EIIVVDSGSTDRT-----VEIAK--EYGAKVY-QRWWDGFGAQRNF--ALELATNDWVLSLDADerltpELADE 91
DPM1_like cd06442
DPM1_like represents putative enzymes similar to eukaryotic DPM1; Proteins similar to ...
 38-100 2.30e-03

DPM1_like represents putative enzymes similar to eukaryotic DPM1; Proteins similar to eukaryotic DPM1, including enzymes from bacteria and archaea; DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. This protein family belongs to Glycosyltransferase 2 superfamily.


Pssm-ID: 133062 [Multi-domain]  Cd Length: 224  Bit Score: 38.67  E-value: 2.30e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 896554602  38 VVIVDDASTDGTWGVLEQevatLHARGIEVVLRRQQQNVG----YVRNFESALlqcsGDIVFLCDQD 100
Cdd:cd06442   30 IIVVDDNSPDGTAEIVRE----LAKEYPRVRLIVRPGKRGlgsaYIEGFKAAR----GDVIVVMDAD 88
Succinoglycan_BP_ExoA cd02525
ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA ...
 7-98 2.72e-03

ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.


Pssm-ID: 133016 [Multi-domain]  Cd Length: 249  Bit Score: 38.75  E-value: 2.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602   7 TVSVALCTWQGERYIAAQLRTVGAQTVLPTQ--VVIVDDASTDGTWGVLeQEVATLHARgiEVVLRRQQQNVGYVRNfeS 84
Cdd:cd02525    1 FVSIIIPVRNEEKYIEELLESLLNQSYPKDLieIIVVDGGSTDGTREIV-QEYAAKDPR--IRLIDNPKRIQSAGLN--I 75

                         90
                 ....*....|....
gi 896554602  85 ALLQCSGDIVFLCD 98
Cdd:cd02525   76 GIRNSRGDIIIRVD 89
GT2_Chondriotin_Pol_N cd06420
N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Chondroitin ...
 25-120 8.73e-03

N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Chondroitin polymerase is a two domain, bi-functional protein. The N-terminal domain functions as a GalNAc transferase. The bacterial chondroitin polymerase catalyzes elongation of the chondroitin chain by alternatively transferring the GlcUA and GalNAc moiety from UDP-GlcUA and UDP-GalNAc to the non-reducing ends of the chondroitin chain. The enzyme consists of N-terminal and C-terminal domains in which the two active sites catalyze the addition of GalNAc and GlcUA, respectively. Chondroitin chains range from 40 to over 100 repeating units of the disaccharide. Sulfated chondroitins are involved in the regulation of various biological functions such as central nervous system development, wound repair, infection, growth factor signaling, and morphogenesis, in addition to its conventional structural roles. In Caenorhabditis elegans, chondroitin is an essential factor for the worm to undergo cytokinesis and cell division. Chondroitin is synthesized as proteoglycans, sulfated and secreted to the cell surface or extracellular matrix.


Pssm-ID: 133042 [Multi-domain]  Cd Length: 182  Bit Score: 36.79  E-value: 8.73e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896554602  25 LRTVGAQTVLPTQVVIVDDASTDGTWGVLEQEVATLHARGIEVvlrrQQQNVGY----VRNfeSALLQCSGD-IVFLcDQ 99
Cdd:cd06420   16 LKSVLNQSILPFEVIIADDGSTEETKELIEEFKSQFPIPIKHV----WQEDEGFrkakIRN--KAIAAAKGDyLIFI-DG 88

                         90       100
                 ....*....|....*....|.
gi 896554602 100 DDLWREDKIETFLRIfdARPG 120
Cdd:cd06420   89 DCIPHPDFIADHIEL--AEPG 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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