|
Name |
Accession |
Description |
Interval |
E-value |
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
117-422 |
3.04e-38 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 140.81 E-value: 3.04e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 117 RVALVLDISDFHDLEQFATRWVMLAGVIMIFVTVLMASFGMERMVRPLSLLAQHIAALRPGVQGQRIEVDPRGSSELHTI 196
Cdd:COG0642 13 LLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 197 ANALNDYLDRNEQFVERERVFISTASHELRTPIAVMTGAAELALEQPglPERARQQMQRVLRTAQSVEQLIELLLVLAR- 275
Cdd:COG0642 93 LLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEEL--DEEQREYLETILRSADRLLRLINDLLDLSRl 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 276 DPARLAARAERIALDQLLPEIVDDHRHLLGDKDLSIGIQAAP--VDIVAPLAVVQAAIGNLLRNAIENSGRG-HIELRLS 352
Cdd:COG0642 171 EAGKLELEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDdlPTVRGDPDRLRQVLLNLLSNAIKYTPEGgTVTVSVR 250
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896564911 353 SS---AVLTLQDPGHGMSPEEIAAIHARMARGERADRGG--GIGLDLIARLCEHLGWTLQLQPCEPRGTRVTLDF 422
Cdd:COG0642 251 REgdrVRISVEDTGPGIPPEDLERIFEPFFRTDPSRRGGgtGLGLAIVKRIVELHGGTIEVESEPGKGTTFTVTL 325
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
199-422 |
7.13e-36 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 131.95 E-value: 7.13e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 199 ALNDYLDRNEQFVERERVFISTASHELRTPIAVMTGAAELALEQPGL-PERARQQMQRVLRTAQSVEQLIELLLVLAR-D 276
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDLsPEERRELLEIIRESAERLLRLIEDLLDLSRlE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 277 PARLAARAERIALDQLLPEIVDDHRHLLGDKDLSIGIQAAPVD--IVAPLAVVQAAIGNLLRNAIENSGRG-HIELRLSS 353
Cdd:COG2205 81 SGKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELplVYADPELLEQVLANLLDNAIKYSPPGgTITISARR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896564911 354 ---SAVLTLQDPGHGMSPEEIAAIHARMARGERADRGGGIGLDL-IAR-LCEHLGWTLQLQPCEPRGTRVTLDF 422
Cdd:COG2205 161 egdGVRISVSDNGPGIPEEELERIFERFYRGDNSRGEGGTGLGLaIVKrIVEAHGGTIWVESEPGGGTTFTVTL 234
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
103-427 |
3.19e-28 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 114.65 E-value: 3.19e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 103 RETAVMVRETQSMGRVALVLDISDFHDLEQFATRWVMLAGVIMIFVTVLMASFGMERMVRPLSLLAQHIAALRPGVQGQR 182
Cdd:COG5002 50 LLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLL 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 183 IEVDPRGSSELHTIANALNDYLDRN----EQFVERERVFISTASHELRTPIAVMTGAAELALEQP-GLPERARQQMQRVL 257
Cdd:COG5002 130 LLGRLSLRLSALLLGLLLLAAVERDitelERLEQMRREFVANVSHELRTPLTSIRGYLELLLDGAaDDPEERREYLEIIL 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 258 RTAQSVEQLIELLLVLAR-DPARLAARAERIALDQLLPEIVDDHRHLLGDKD--LSIGIQAAPVDIVA-PLAVVQaAIGN 333
Cdd:COG5002 210 EEAERLSRLVNDLLDLSRlESGELKLEKEPVDLAELLEEVVEELRPLAEEKGieLELDLPEDPLLVLGdPDRLEQ-VLTN 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 334 LLRNAIENSGRG-HIELRLSSS---AVLTLQDPGHGMSPEEIAAIHARMARGE--RADRGGGIGLDL-IAR-LCEHLGWT 405
Cdd:COG5002 289 LLDNAIKYTPEGgTITVSLREEddqVRISVRDTGIGIPEEDLPRIFERFYRVDksRSRETGGTGLGLaIVKhIVEAHGGR 368
|
330 340
....*....|....*....|..
gi 896564911 406 LQLQPCEPRGTRVTLDFGASRP 427
Cdd:COG5002 369 IWVESEPGKGTTFTITLPLARE 390
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
134-422 |
1.71e-23 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 102.23 E-value: 1.71e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 134 ATRWVMLAGVIMIFVTVLMASFGMERMVRPLSLLAQHIAALRpgvQGQRIEVDPRGSSELHTIANALNDYLDRNE--QFV 211
Cdd:PRK11100 180 SERRILWAGALLLGIALLIGAGVVWWLNRSIRRLTRYADAVT---EGKPVPLPKLGSSELRELAQALESMRVKLEgkAYV 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 212 ERervFISTASHELRTPIAVMTGAAELALEQPGlPERARQQMQRVLRTAQSVEQLIELLLVLARDPARLA-ARAERIALD 290
Cdd:PRK11100 257 EQ---YVQTLTHELKSPLAAIRGAAELLQEDPP-PEDRARFTGNILTQSARLQQLIDRLLELARLEQRQElEVLEPVALA 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 291 QLLPEIVDDHRHLLGDKDLSIGIQAAPVDIVAPLAVVQAAIGNLLRNAIE--NSGrGHIELRLS---SSAVLTLQDPGHG 365
Cdd:PRK11100 333 ALLEELVEAREAQAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDfsPEG-GTITLSAEvdgEQVALSVEDQGPG 411
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 896564911 366 MSPEEIAAIHAR---MARGERADRGGGIGLDL---IARLceHLGwTLQLQPCEPRGTRVTLDF 422
Cdd:PRK11100 412 IPDYALPRIFERfysLPRPANGRKSTGLGLAFvreVARL--HGG-EVTLRNRPEGGVLATLTL 471
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
106-422 |
9.08e-20 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 90.91 E-value: 9.08e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 106 AVMVRETQSMGRVALVLDISDFHDLEQFATRWVMLAGVIMIFVTVLMASFGMERMVRPLSLLAQHIAALRPGVQGQRIEV 185
Cdd:TIGR01386 134 ALPGGKGRKPVQITVALDINAHTHLLDALRKWLILIAVLLVLLTALLGWWITRLGLEPLRRLSAVAARISPESLDQRLDP 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 186 DPRgSSELHTIANALNDYLDRNEQFVERERVFISTASHELRTPIAVMTGAAELALEQPGLPERARQQMQRVLRTAQSVEQ 265
Cdd:TIGR01386 214 SRA-PAELRELAQSFNAMLGRLEDAFQRLSQFSADLAHELRTPLTNLLGQTQVALSQPRTGEEYREVLESNLEELERLSR 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 266 LIELLLVLAR-DPARLAARAERIALDQLLPEIVDDHRHLLGDKDLSIGIQAAPVdIVAPLAVVQAAIGNLLRNAIENSGR 344
Cdd:TIGR01386 293 MVSDMLFLARaDNGQLALERVRLDLAAELAKVAEYFEPLAEERGVRIRVEGEGL-VRGDPQMFRRAISNLLSNALRHTPD 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 345 GH-IELRL---SSSAVLTLQDPGHGMSPEEIAAIHARMARGERADR----GGGIGLDLIARLCEHLGWTLQLQPcEPRGT 416
Cdd:TIGR01386 372 GGtITVRIerrSDEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPARSnsgeGTGLGLAIVRSIMEAHGGRASAES-PDGKT 450
|
....*.
gi 896564911 417 RVTLDF 422
Cdd:TIGR01386 451 RFILRF 456
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
137-398 |
1.50e-19 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 90.48 E-value: 1.50e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 137 WVMLAGVIMIFVTVLMAsfgmeRMVRPLSLLAQHIAALRPG----VQGQRIevdprgSSELHTIANALNDYLDRNEQFVE 212
Cdd:PRK10337 167 WLVALPIMLIILMVLLG-----RELAPLKKLALALRMRDPDsetpLNATGV------PSEVRPLVEALNQLFARTHAMMV 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 213 RERVFISTASHELRTPIA---VMTGAAELALEQPGLPERARQQM-QRVLRTAQSVEQlielLLVLAR-DPARLAARAERI 287
Cdd:PRK10337 236 RERRFTSDAAHELRSPLAalkVQTEVAQLSDDDPQARKKALLQLhAGIDRATRLVDQ----LLTLSRlDSLDNLQDVAEI 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 288 ALDQLLPEIVDDHRHLL--GDKDLSIGIQAAPVDIVAPLAVVQAAIGNLLRNAIENSGRGH-IELRLSSSAvLTLQDPGH 364
Cdd:PRK10337 312 PLEDLLQSAVMDIYHTAqqAGIDVRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSvVDVTLNARN-FTVRDNGP 390
|
250 260 270
....*....|....*....|....*....|....*....
gi 896564911 365 GMSPEEIAAIHARMAR--GERADrGGGIGLDL---IARL 398
Cdd:PRK10337 391 GVTPEALARIGERFYRppGQEAT-GSGLGLSIvrrIAKL 428
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
215-422 |
4.39e-18 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 84.57 E-value: 4.39e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 215 RVFISTASHELRTPIAVMTGAAELALEQPGL-PERARQQMQRVLRTAQSVEQLIELLLVLAR-DPARLAARAERIALDQL 292
Cdd:TIGR02966 115 RDFVANVSHELRTPLTVLRGYLETLADGPDEdPEEWNRALEIMLEQSQRMQSLVEDLLTLSRlESAASPLEDEPVDMPAL 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 293 LPEIVDDHRHLLGDKDLSIGIQA-APVDIVAPLAVVQAAIGNLLRNAIENSGRG-HIELRLS---SSAVLTLQDPGHGMS 367
Cdd:TIGR02966 195 LDHLRDEAEALSQGKNHQITFEIdGGVDVLGDEDELRSAFSNLVSNAIKYTPEGgTITVRWRrdgGGAEFSVTDTGIGIA 274
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 896564911 368 PEEIAAIHARMARGERA---DRGG-GIGLDLIARLCEHLGWTLQLQPCEPRGTRVTLDF 422
Cdd:TIGR02966 275 PEHLPRLTERFYRVDKSrsrDTGGtGLGLAIVKHVLSRHHARLEIESELGKGSTFSFIF 333
|
|
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
132-404 |
4.61e-17 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 83.15 E-value: 4.61e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 132 QFATRWVMLAGVIMIFVTVLMASFGMERMVRPLSLLAQHIAALRPGVQGQRIEVdpRGSSELHTIANALNDY-------L 204
Cdd:NF040691 184 ALVRGTLLLGGLALVVLLGLIAWLVTRQVVAPVRSAARTAERFAAGDLSERMPV--KGEDDLARLARSFNQMadslqrqI 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 205 DRNEQFVERERVFISTASHELRTPIAVMTGAAEL-ALEQPGLPERARQQMQRVLRTAQSVEQLIELLLVLARDPARLAA- 282
Cdd:NF040691 262 RQLEELSRLQQRFVSDVSHELRTPLTTIRMAADViHDSRDDFDPATARSAELLHTELDRFESLLSDLLEISRFDAGAAEl 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 283 RAERIALDQLLPEIVDDHRHLLGDKDLSIGIQAAPVDIVAPLAV--VQAAIGNLLRNAIENSGRGHIELRLSS--SAV-L 357
Cdd:NF040691 342 DVEPVDLRPLVRRVVDALRQLAERAGVELRVDAPGTPVVAEVDPrrVERVLRNLVVNAIEHGEGKPVVVTVAQddTAVaV 421
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 896564911 358 TLQDPGHGMSPEEIAAIHARMARGE--RADRGGGIGLDLI-----ARLceHLGW 404
Cdd:NF040691 422 TVRDHGVGLKPGEVALVFDRFWRADpaRARTTGGTGLGLAialedARL--HGGW 473
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
163-422 |
1.72e-16 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 80.78 E-value: 1.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 163 PLSLLAQHIAALRPGVQGQRIEVDPRGSSELHTIANALND-----YLDRNEQFVERERV-----FISTASHELRTPIAVM 232
Cdd:COG5000 140 PELDLAELLREALERGWQEEIELTRDGRRTLLVRASPLRDdgyviVFDDITELLRAERLaawgeLARRIAHEIKNPLTPI 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 233 TGAAE-----LALEQPGLPERARQQMQRVLRTAQSVEQLIELLLVLARDPArlaARAERIALDQLLPEIVDDHRHLLGDK 307
Cdd:COG5000 220 QLSAErlrrkLADKLEEDREDLERALDTIIRQVDRLKRIVDEFLDFARLPE---PQLEPVDLNELLREVLALYEPALKEK 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 308 DLSIGIQAAPVDIVAPLAVVQ--AAIGNLLRNAIE-NSGRGHIELRLS---SSAVLTLQDPGHGMSPEEIaaiharmarg 381
Cdd:COG5000 297 DIRLELDLDPDLPEVLADRDQleQVLINLLKNAIEaIEEGGEIEVSTRredGRVRIEVSDNGPGIPEEVL---------- 366
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 896564911 382 ERA--------DRGGGIGLDLIARLCEHLGWTLQLQPCEPRGTRVTLDF 422
Cdd:COG5000 367 ERIfepffttkPKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRL 415
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
37-422 |
1.57e-15 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 78.33 E-value: 1.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 37 EHAEHAAWRALLNSE---LDSIVEHVEHE-----------PHYRWqdSDTLSLY----RFdAVNLPDslRTLHPGLHDGV 98
Cdd:NF012163 58 QYAQHGNWRFLRNNGdrwVRQLLRTLEHDndsdkpgpglpDHLGW--RSRLWLVdanhRF-VVGPPD--PVSDDGTRRPI 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 99 MVKGRETAVMVreTQSMGRVALVLDISdfHDLEQFATRWVMlagVIMIFVTVLMASFGMERMVR-PLSLLAQHIAALRPG 177
Cdd:NF012163 133 LVNGQEVGALG--ASPVERLTRNTDIN--FDSQQKRASWLI---VALALLLAALAAFLLARGLLaPVKRLVEATHRLAAG 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 178 VQGQRIEvdPRGSSELHTIANALN---DYLDRNEQfveRERVFISTASHELRTPIAVMTGaaELALEQPGLPERARQQMQ 254
Cdd:NF012163 206 DYTTRVT--PTSNDELGKLAQDFNqlaSTLEKNEQ---MRRDFMADISHELRTPLAVLRA--ELEAIQDGIRKFTPESLD 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 255 RVLRTAQSVEQLIELLLVLAR-DPARLAARAERIALDQLLPEIVDDHRHLLGDKDLSIGIQ-AAPVDIVAPLAVVQAAIG 332
Cdd:NF012163 279 SLQAEVGTLTKLVDDLHDLSMsDEGALAYQKASVDLVPLLEVEGGAFRERFASAGLELEVSlPDSSLVFGDRDRLMQLFN 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 333 NLLRNAI---ENSGRGHIEL-RLSSSAVLTLQDPGHGMSPEEIAAIHARMARGE----RADRGGGIGLDLIARLCEHLGW 404
Cdd:NF012163 359 NLLENSLrytDSGGSLHISAsQRPKEVTLTVADSAPGVSDEQLARLFERFYRVEvsrnRASGGSGLGLAISLNIVQAHGG 438
|
410
....*....|....*...
gi 896564911 405 TLQLQPCEPRGTRVTLDF 422
Cdd:NF012163 439 TLHAAHSPLGGLRIVVTL 456
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
330-420 |
3.96e-15 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 70.86 E-value: 3.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 330 AIGNLLRNAIE---NSGRGHIELRLSSSAVLTLQDPGHGMSPEEIAAIHARMARGERADRGG-GIGLDLIARLCEHLGWT 405
Cdd:pfam02518 9 VLSNLLDNALKhaaKAGEITVTLSEGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRGGGGtGLGLSIVRKLVELLGGT 88
|
90
....*....|....*
gi 896564911 406 LQLQPCEPRGTRVTL 420
Cdd:pfam02518 89 ITVESEPGGGTTVTL 103
|
|
| TMAO_torS |
TIGR02956 |
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the ... |
139-427 |
6.66e-14 |
|
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems]
Pssm-ID: 274362 [Multi-domain] Cd Length: 968 Bit Score: 74.04 E-value: 6.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 139 MLAGVIMIFVtvlMASFGMERMVRPLsllAQHIAALRPGVQGQ-RIEVDPRGSSELHTIANAL---------NDYLDRNE 208
Cdd:TIGR02956 338 MLGLVILVFI---MWRVVYRSVILRL---NQHTQALLRLALGDlDISLDARGDDELAHMGRAIeafrdtaahNLKLQADE 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 209 QFVERE-----------------------------------------------RVFISTASHELRTPIAVMTGAAELaLE 241
Cdd:TIGR02956 412 RQVAQElqehkesleqlvaqrtqelaetnerlnaevknhakaraeaeeanrakSAFLATMSHEIRTPLNGILGTLEL-LG 490
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 242 QPGLPERARQQMQRVLRTAQSVEQLIELLLVLARDPA-RLAARAERIALDQLLPEIVddhrHLLGDKDLSIGIQAA---P 317
Cdd:TIGR02956 491 DTGLTSQQQQYLQVINRSGESLLDILNDILDYSKIEAgHLSISPRPFDLNALLDDVH----HLMVSRAQLKGIQLRlniP 566
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 318 VDI----VAPLAVVQAAIGNLLRNAIENSGRGHIELRLS----SSAVLTLQDPGHGMSPEEIAAIHA--RMARGERADRG 387
Cdd:TIGR02956 567 EQLpnwwQGDGPRIRQVLINLVGNAIKFTDRGSVVLRVSlnddSSLLFEVEDTGCGIAEEEQATLFDafTQADGRRRSGG 646
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 896564911 388 GGIGLDLIARLCEHLGWTLQLQPCEPRGT--RVTLDFGASRP 427
Cdd:TIGR02956 647 TGLGLAISQRLVEAMDGELGVESELGVGScfWFTLPLTRGKP 688
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
330-422 |
1.74e-13 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 66.52 E-value: 1.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 330 AIGNLLRNAIENSG-RGHIELRLSSS---AVLTLQDPGHGMSPEEIAAIHARMARGERADR---GGGIGLDLIARLCEHL 402
Cdd:smart00387 9 VLSNLLDNAIKYTPeGGRITVTLERDgdhVEITVEDNGPGIPPEDLEKIFEPFFRTDKRSRkigGTGLGLSIVKKLVELH 88
|
90 100
....*....|....*....|
gi 896564911 403 GWTLQLQPCEPRGTRVTLDF 422
Cdd:smart00387 89 GGEISVESEPGGGTTFTITL 108
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
142-422 |
2.08e-13 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 71.15 E-value: 2.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 142 GVIMIFVTVLMASFGMERMVRPLSLLAQHIAA-----LRPgvqgqrieVDPRGSS-ELHTIANALNDYLDRNEQFVERER 215
Cdd:PRK10755 67 SLVMVSLTLLICFQAVRWITRPLAELQKELEArtadnLTP--------IAIHSSTlEIEAVTSALNQLVSRLTSTLDQER 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 216 VFISTASHELRTPIAVMTGAAELaLEQPGLPErARQQMQRVLRTAQSVEQlielLLVLARDPARLAA---RAERIALDQL 292
Cdd:PRK10755 139 LFTADVAHELRTPLAGIRLHLEL-LEKQHHID-VAPLIARLDQMMHTVEQ----LLQLARAGQSFSSghyQTVKLLEDVI 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 293 LPeIVDDHRHLLGDKDLSIGIQAAPVDIVAPlavvqaaiGN------LLRNAIENSGR-----GHIELRLSS---SAVLT 358
Cdd:PRK10755 213 LP-SQDELSEMLEQRQQTLLLPESAADITVQ--------GDatllrlLLRNLVENAHRyspegSTITIKLSQedgGAVLA 283
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896564911 359 LQDPGHGMSPEEIAAIHARMARGERadRGGGIGLDL--IARLCE-HLG-WTLQLQPcEPRGTRVTLDF 422
Cdd:PRK10755 284 VEDEGPGIDESKCGELSKAFVRMDS--RYGGIGLGLsiVSRITQlHHGqFFLQNRQ-ERSGTRAWVWL 348
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
11-419 |
3.36e-13 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 71.35 E-value: 3.36e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 11 RRVVWWLLGYLALLSIAVFSVGNYVHEHAEHAAWRALLNSELDSIVEHVEHEPHYRWQDSDTLSLYRFDAVNLPDSLRTL 90
Cdd:COG4251 76 AALALLLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLL 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 91 HPGLHDGVMVKGRETAVMVRETQSMGRVALVLDISDFHDLEQFATRWVMLAGVIMIFVTVLMASFGMERMVRPLSLLAQH 170
Cdd:COG4251 156 LLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLL 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 171 IAALRPGVQGQRIEVDPRGSSELHTIANALNDYLDRNEQFV----ERERvFISTASHELRTPIAVMTGAAELALEQPG-- 244
Cdd:COG4251 236 VLLLLLILLLLLLILVLELLELRLELEELEEELEERTAELErsneELEQ-FAYVASHDLREPLRKISGFSQLLEEDYGdk 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 245 LPERARQQMQRVLRTAQSVEQLIELLLVLARDpARLAARAERIALDQLLPEIVDDHRHLLGDKDLSIGIQAAPVDIVAPL 324
Cdd:COG4251 315 LDEEGREYLERIRDAAERMQALIDDLLAYSRV-GRQELEFEPVDLNELLEEVLEDLEPRIEERGAEIEVGPLPTVRGDPT 393
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 325 AVVQAaIGNLLRNAIENSGRG---HIEL---RLSSSAVLTLQDPGHGMSPEEIAAIHARMARGERADR--GGGIGLDLIA 396
Cdd:COG4251 394 LLRQV-FQNLISNAIKYSRPGeppRIEIgaeREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRLHSRDEyeGTGIGLAIVK 472
|
410 420
....*....|....*....|...
gi 896564911 397 RLCEHLGWTLQLQPCEPRGTRVT 419
Cdd:COG4251 473 KIVERHGGRIWVESEPGEGATFY 495
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
223-422 |
5.57e-13 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 69.83 E-value: 5.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 223 HELRTPIAVMTGAAELA---LEQPGLPERARQQMQRVLRTAQSVEQLIELLLVLARdpaRLAARAERIALDQLLPEIVDD 299
Cdd:COG4191 151 HEINNPLAAILGNAELLrrrLEDEPDPEELREALERILEGAERAAEIVRSLRAFSR---RDEEEREPVDLNELIDEALEL 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 300 HRHLLGDK--DLSIGIQAAPVDIVAPLAVVQAAIGNLLRNAI---ENSGRGHIELRLSSS---AVLTLQDPGHGMSPEEI 371
Cdd:COG4191 228 LRPRLKARgiEVELDLPPDLPPVLGDPGQLEQVLLNLLINAIdamEEGEGGRITISTRREgdyVVISVRDNGPGIPPEVL 307
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 896564911 372 AAIharmarGE------RADRGGGIGLDLIARLCEHLGWTLQLQPCEPRGTRVTLDF 422
Cdd:COG4191 308 ERI------FEpffttkPVGKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITL 358
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
123-422 |
6.39e-13 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 70.05 E-value: 6.39e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 123 DISdfHDLEQFATRW--VMLAGVIMIFVTVLMASfGMERMVRPLSLLAQHIAAlrpGVQGQRieVDPRGSSELHTIA--- 197
Cdd:PRK10549 155 DIN--FDKQQRRTSWliVALSTLLAALATFLLAR-GLLAPVKRLVEGTHKLAA---GDFTTR--VTPTSRDELGRLAqdf 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 198 NALNDYLDRNEQFverERVFISTASHELRTPIAVMTGaaELALEQPGLperaRQQMQRVLRTAQS-VEQLIELL-----L 271
Cdd:PRK10549 227 NQLASTLEKNEQM---RRDFMADISHELRTPLAVLRG--ELEAIQDGV----RKFTPESVASLQAeVGTLTKLVddlhqL 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 272 VLArDPARLAARAERIALDQLLPEIVDDHRHLLGDKDLSIGIQAAPVDIV--APLAVVQaaignLLRNAIENS------- 342
Cdd:PRK10549 298 SLS-DEGALAYRKTPVDLVPLLEVAGGAFRERFASRGLTLQLSLPDSATVfgDPDRLMQ-----LFNNLLENSlrytdsg 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 343 GRGHIELRLSSSA-VLTLQDPGHGMSPEEIAAIHARMARGE----RADRGGGIGLDLIARLCEHLGWTLQLQPCEPRGTR 417
Cdd:PRK10549 372 GSLHISAEQRDKTlRLTFADSAPGVSDEQLQKLFERFYRTEgsrnRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVS 451
|
....*
gi 896564911 418 VTLDF 422
Cdd:PRK10549 452 ITVEL 456
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
212-275 |
1.71e-11 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 59.15 E-value: 1.71e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 896564911 212 ERERVFISTASHELRTPIAVMTGAAELALEQPGLPERARQQMQRVLRTAQSVEQLIELLLVLAR 275
Cdd:cd00082 2 QAKGEFLANVSHELRTPLTAIRGALELLEEELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
128-420 |
8.11e-11 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 63.64 E-value: 8.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 128 HDLEQFATRWVMLAGVI--MIFVTVLMASFGMERMVRPLSLLAQHIAA--LRPGVQGQRIEVdprgssELHTIANALNDY 203
Cdd:PRK09835 178 HYINDLKNKLIMTASVIslLIVFIVLLAVHKGHAPIRSVSRQIQNITSkdLDVRLDPQTVPI------ELEQLVLSFNHM 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 204 LDRNEQFVERERVFISTASHELRTPIAVMTGAAELALEQpglpERARQQMQRVLRTA----QSVEQLIELLLVLAR-DPA 278
Cdd:PRK09835 252 IERIEDVFTRQSNFSADIAHEIRTPITNLITQTEIALSQ----SRSQKELEDVLYSNleelTRMAKMVSDMLFLAQaDNN 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 279 RLaaRAERIALD--QLLPEIVDDHRHLLGDKDLSIGIQAAPVDIVAPLAVVQAAIGNLLRNAIENSGRGH-IELRLSSSA 355
Cdd:PRK09835 328 QL--IPEKKMLDlaDEVGKVFDFFEAWAEERGVELRFVGDPCQVAGDPLMLRRAISNLLSNALRYTPAGEaITVRCQEVD 405
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 896564911 356 ---VLTLQDPGHGMSPEEIAAIHARMAR----GERADRGGGIGLDLIARLCEHLGWTLQLQPcEPRGTRVTL 420
Cdd:PRK09835 406 hqvQLVVENPGTPIAPEHLPRLFDRFYRvdpsRQRKGEGSGIGLAIVKSIVVAHKGTVAVTS-DARGTRFVI 476
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
217-275 |
3.05e-10 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 55.68 E-value: 3.05e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 896564911 217 FISTASHELRTPIAVMTGAAELaLEQPGLPERARQQMQRVLRTAQSVEQLIELLLVLAR 275
Cdd:pfam00512 5 FLANLSHELRTPLTAIRGYLEL-LRDEKLDEEQREYLETILRSAERLLRLINDLLDLSR 62
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
182-420 |
1.12e-09 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 60.00 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 182 RIEVDPrgSSELHTIANALNDYLDRNEQFVERERVFISTASHELRTPIAVMTGAAELaLEQPGLPERarqqmQRVLRTAQ 261
Cdd:PRK10604 182 RIHFDE--GSSLERLGVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEM-SDNLSAAES-----QALNRDIG 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 262 SVEQLIELLLVLAR-DPARLAARAERIALDQLLPEIVDDHRHLLGDKDLSIGIQAAPVDIVAPLAVVQAAIGNLLRNAIE 340
Cdd:PRK10604 254 QLEALIEELLTYARlDRPQNELHLSEPDLPAWLSTHLADIQAVTPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNALR 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 341 NSGrGHIELRLS---SSAVLTLQDPGHGMSPEEIAAIHARMAR----GERADRGGGIGLDLIARLCEHLGWTLQLQPCEP 413
Cdd:PRK10604 334 YAH-SRVRVSLLldgNQACLIVEDDGPGIPPEERERVFEPFVRldpsRDRATGGCGLGLAIVHSIALAMGGSVNCDESEL 412
|
....*..
gi 896564911 414 RGTRVTL 420
Cdd:PRK10604 413 GGARFSF 419
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
194-420 |
1.16e-09 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 59.86 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 194 HTIANALNDYLDRNEQFVERERVFistaSHELRTPIAVMTGAAELaleqpGLPERARQQMQRVLRTAQsveQLIELLLVL 273
Cdd:COG3290 173 RTELERLEEELEGVKELAEALRAQ----RHDFRNHLHTISGLLQL-----GEYDEALEYIDEISEELQ---ELIDSLLSR 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 274 ARDPArLA---------ARAERIALDqllpeiVDDHRHLlgdKDLSIgiqaAPVDIVAplavvqaAIGNLLRNAIE---- 340
Cdd:COG3290 241 IGNPV-LAalllgkaarARERGIDLT------IDIDSDL---PDLPL----SDTDLVT-------ILGNLLDNAIEavek 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 341 -NSGRGHIELRLSSSA---VLTLQDPGHGMSPEEIAAIharMARGE--RADRGGGIGLDLIARLCEHLGWTLQLQPCEPR 414
Cdd:COG3290 300 lPEEERRVELSIRDDGdelVIEVEDSGPGIPEELLEKI---FERGFstKLGEGRGLGLALVKQIVEKYGGTIEVESEEGE 376
|
....*.
gi 896564911 415 GTRVTL 420
Cdd:COG3290 377 GTVFTV 382
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
162-417 |
1.21e-09 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 59.64 E-value: 1.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 162 RPLSLL--AQHIAALR--PGVQGQRIEVdPRGSSELHTIANAlndyldrneqfverERVFISTASHELRTPIAVMTGAAE 237
Cdd:PRK11006 163 RPLTLVlnNGRHLEIRvmPYTEGQLLMV-ARDVTQMHQLEGA--------------RRNFFANVSHELRTPLTVLQGYLE 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 238 LALEQP---GLPERARQQMQRVLRtaqSVEQLIELLLVLARDPArlaarAERIALDqllpEIVDDHRHL-LGDKD---LS 310
Cdd:PRK11006 228 MMQDQPlegALREKALHTMREQTQ---RMEGLVKQLLTLSKIEA-----APTIDLN----EKVDVPMMLrVLEREaqtLS 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 311 IGIQAAPVDIVAPLAV------VQAAIGNLLRNAIENSGRG-HIE---LRLSSSAVLTLQDPGHGMSPEEIAAIHARMAR 380
Cdd:PRK11006 296 QGKHTITFEVDNSLKVfgnedqLRSAISNLVYNAVNHTPEGtHITvrwQRVPQGAEFSVEDNGPGIAPEHIPRLTERFYR 375
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 896564911 381 GERA---DRGG-GIGLDLIARLCEHLGWTLQLQPCEPRGTR 417
Cdd:PRK11006 376 VDKArsrQTGGsGLGLAIVKHALSHHDSRLEIESEVGKGTR 416
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
133-394 |
1.37e-09 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 59.56 E-value: 1.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 133 FATRWVMLAgVIMIFVTVLM--ASFGMERMVRPLSLLAQHIAalrpgvQGQrIEVDP---RGSSELHTIANALNDYLDRN 207
Cdd:PRK09470 165 FDRPLLLLL-VTMLVSTPLLlwLAWSLAKPARKLKNAADEVA------QGN-LRQHPeleTGPQEFRQAGASFNQMVTAL 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 208 EQFVERERVFISTASHELRTPIAVMTGAAELALEQPG-LPERARQQMQrvlrtAQSVEQLIELLLVLARDPARLAARAER 286
Cdd:PRK09470 237 ERMMTSQQRLLSDISHELRTPLTRLQLATALLRRRQGeSKELERIETE-----AQRLDSMINDLLVLSRNQQKNHLERET 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 287 IALDQLLPEIVDD------HRHllgdKDLSIGIQAAPVDIVAPLAVVQAAIGNLLRNAIEnSGRGHIELRLSSSA---VL 357
Cdd:PRK09470 312 FKANSLWSEVLEDakfeaeQMG----KSLTVSAPPGPWPINGNPNALASALENIVRNALR-YSHTKIEVAFSVDKdglTI 386
|
250 260 270
....*....|....*....|....*....|....*....
gi 896564911 358 TLQDPGHGMSPEEIAAIHARMAR-GERADR-GGGIGLDL 394
Cdd:PRK09470 387 TVDDDGPGVPEEEREQIFRPFYRvDEARDReSGGTGLGL 425
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
217-275 |
1.83e-09 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 53.72 E-value: 1.83e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 896564911 217 FISTASHELRTPIAVMTGAAELaLEQPGLPERARQQMQRVLRTAQSVEQLIELLLVLAR 275
Cdd:smart00388 5 FLANLSHELRTPLTAIRGYLEL-LLDTELSEEQREYLETILREAERLLRLINDLLDLSR 62
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
327-422 |
1.96e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 52.02 E-value: 1.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 327 VQAAIGNLLRNAIENSGRG-HIELRLSS--SAVLTLQDPGHGMSPEEIAAIHARMARGE-RADRGGGIGLDLIARLCEHL 402
Cdd:cd16940 14 LFLLLRNLVDNAVRYSPQGsRVEIKLSAddGAVIRVEDNGPGIDEEELEALFERFYRSDgQNYGGSGLGLSIVKRIVELH 93
|
90 100
....*....|....*....|
gi 896564911 403 GWTLQLQPCEPRGTRVTLDF 422
Cdd:cd16940 94 GGQIFLGNAQGGGLEAWVRL 113
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
135-420 |
4.96e-08 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 55.02 E-value: 4.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 135 TRWVMLAGVIMIFVTVLMASFGMERMVRPLSLLAQHIAALRpgvQGQRIEVDPRGSSELHTIANALNDYLDRNEQFVERE 214
Cdd:COG2972 156 RRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVE---KGDLVRLEVSGNDEIGILARSFNEMVERIKELIEEV 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 215 RVfistASHELRTpiavmtgaAELALEQpglperarQQMQR--------------VLRTAQSVEQLIELLLVLARdpARL 280
Cdd:COG2972 233 YE----LELEKKE--------AELKALQ--------AQINPhflfntlnsirwlaELEDPEEAEEMLEALSKLLR--YSL 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 281 AARAERIALDQllpEIvdDH-RHLL-------GDK-DLSIGIQAAPVDIVAPLAVVQaaigNLLRNAIE-----NSGRGH 346
Cdd:COG2972 291 SKGDELVTLEE---EL--ELiKSYLeiqklrfGDRlEVEIEIDEELLDLLIPKLILQ----PLVENAIEhgiepKEGGGT 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 347 IELRLS---SSAVLTLQDPGHGMSPEEIAAIHARMargERADRGGGIGLDLIARLCEHL---GWTLQLQPCEPRGTRVTL 420
Cdd:COG2972 362 IRISIRkegDRLVITVEDNGVGMPEEKLEKLLEEL---SSKGEGRGIGLRNVRERLKLYygeEYGLEIESEPGEGTTVTI 438
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
217-420 |
7.05e-08 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 54.74 E-value: 7.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 217 FISTASHELRTPIAVMTGAAELaLEQPGLPERAR-QQMQRVLRTAQSVEQLI-ELLLVLARDPARLAARAERIALDQLLP 294
Cdd:PRK09959 715 FLATMSHEIRTPISSIMGFLEL-LSGSGLSKEQRvEAISLAYATGQSLLGLIgEILDVDKIESGNYQLQPQWVDIPTLVQ 793
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 295 EIVDDHRHLLGDKDLSIGIQAAPVD----IVAPLAVVQaAIGNLLRNAIENSGRGHIELRLS------SSAV--LTLQDP 362
Cdd:PRK09959 794 NTCHSFGAIAASKSIALSCSSTFPDhylvKIDPQAFKQ-VLSNLLSNALKFTTEGAVKITTSlghiddNHAVikMTIMDS 872
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 363 GHGMSPEEIAAIHARMARGE--RADRGGGIGLDLIARLCEHLGWTLQLQPCEPRGTRVTL 420
Cdd:PRK09959 873 GSGLSQEEQQQLFKRYSQTSagRQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTI 932
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
151-428 |
9.22e-08 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 54.53 E-value: 9.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 151 LMASFgmERMVRPLSLLAQHIAALrpgVQGQrievdprgSSELHTIANALNDYLDRNEQFVERERVFISTASHELRTPIA 230
Cdd:PRK11466 394 LMDAF--RSNVHALNRHREQLAAQ---VKAR--------TAELQELVIEHRQARAEAEKASQAKSAFLAAMSHEIRTPLY 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 231 VMTGAAELALEQPGLPeRARQQMQRVLRTAQSVEQLIELLLvlarDPARLAARAERIALDQ--LLP-EIVDDHRHLLGDK 307
Cdd:PRK11466 461 GILGTAQLLADNPALN-AQRDDLRAITDSGESLLTILNDIL----DYSAIEAGGKNVSVSDepFEPrPLLESTLQLMSGR 535
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 308 dlsigIQAAPVDIVAPLA------------VVQAAIGNLLRNAIENSGRGHIELRL---SSSAVLTLQDPGHGMSPEEIA 372
Cdd:PRK11466 536 -----VKGRPIRLATDIAddlptalmgdprRIRQVITNLLSNALRFTDEGSIVLRSrtdGEQWLVEVEDSGCGIDPAKLA 610
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 896564911 373 AIHARMARGErADRGG-GIGLDLIARLCEHLGWTLQLQPCEPRGTRVTLDFGASRPR 428
Cdd:PRK11466 611 EIFQPFVQVS-GKRGGtGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRVAT 666
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
207-403 |
2.84e-07 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 52.26 E-value: 2.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 207 NEQFVER----ERVfISTASHELRTPIAvmtgAAELALE-------------QPGLPERARQQMQRVLRTaqsVEQLIEL 269
Cdd:PRK09303 141 NETLLEQlkfkDRV-LAMLAHDLRTPLT----AASLALEtlelgqidedtelKPALIEQLQDQARRQLEE---IERLITD 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 270 LLVLARDP-ARLAARAERIALDQLLPEIVDDHRHLLGDKdlSIGIQAapvDIVAPLAVVQA-------AIGNLLRNAIEN 341
Cdd:PRK09303 213 LLEVGRTRwEALRFNPQKLDLGSLCQEVILELEKRWLAK--SLEIQT---DIPSDLPSVYAdqerirqVLLNLLDNAIKY 287
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 896564911 342 SGR-GHIEL----RLSSSAVLTLQDPGHGMSPEEIAAI---HARMARGERADrGGGIGLDLIARLCE-HLG 403
Cdd:PRK09303 288 TPEgGTITLsmlhRTTQKVQVSICDTGPGIPEEEQERIfedRVRLPRDEGTE-GYGIGLSVCRRIVRvHYG 357
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
196-394 |
7.65e-07 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 51.58 E-value: 7.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 196 IANALND-YLDRNEQF----VERERV---FISTASHELRTPIAVMTGAAE-----LALEQPGLPERARQQMQRVLRTAQS 262
Cdd:PRK10490 638 IANALERlTLTASEEQarlaSEREQLrnaLLAALSHDLRTPLTVLFGQAEiltldLASEGSPHARQASEIRQQVLNTTRL 717
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 263 VEQLIelllvlarDPARLAARAERIALD-QLLPEIVDDHRHLLgdkDLSIGIQAAPVDIVAPLAVV-------QAAIGNL 334
Cdd:PRK10490 718 VNNLL--------DMARIQSGGFNLRKEwLTLEEVVGSALQML---EPGLSGHPINLSLPEPLTLIhvdgplfERVLINL 786
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 896564911 335 LRNAIENSGRgHIELRLSSSAV-----LTLQDPGHGMSPEEIAAIHARMARGERADRGGGIGLDL 394
Cdd:PRK10490 787 LENAVKYAGA-QAEIGIDAHVEgerlqLDVWDNGPGIPPGQEQLIFDKFARGNKESAIPGVGLGL 850
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
192-421 |
9.07e-07 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 51.18 E-value: 9.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 192 ELHTIANALNDYLD-------------------------RNEQFVERERVFISTASHELRTPIAVMTGAAEL------AL 240
Cdd:PRK15347 351 ELGSIAKAYNQLLDtlneqydtlenkvaertqalaeakqRAEQANKRKSEHLTTISHEIRTPLNGVLGALELlqntplTA 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 241 EQPGLPERARQqmqrvlrTAQSVEQLIELLLVLARDPA-RLAARAERIALDQLLpeivDDHRHLLGDKDLSIGIQ----- 314
Cdd:PRK15347 431 EQMDLADTARQ-------CTLSLLAIINNLLDFSRIESgQMTLSLEETALLPLL----DQAMLTIQGPAQSKSLTlrtfv 499
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 315 AAPVDIVA---PLAVVQAAIgNLLRNAIENSGRGHIELRLSSSA---VLTLQDPGHGMSPEEIAAIHARMARGERADRGG 388
Cdd:PRK15347 500 GAHVPLYLhldSLRLRQILV-NLLGNAVKFTETGGIRLRVKRHEqqlCFTVEDTGCGIDIQQQQQIFTPFYQADTHSQGT 578
|
250 260 270
....*....|....*....|....*....|...
gi 896564911 389 GIGLDLIARLCEHLGWTLQLQPCEPRGTRVTLD 421
Cdd:PRK15347 579 GLGLTIASSLAKMMGGELTLFSTPGVGSCFSLV 611
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
331-420 |
1.50e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 46.51 E-value: 1.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 331 IGNLLRNAIENSGR-----GHIELRLS---SSAVLTLQDPGHGMSPEEIAAIharMARG--ERADRGGGIGLDLIARLCE 400
Cdd:cd16915 5 VGNLIDNALDALAAtgapnKQVEVFLRdegDDLVIEVRDTGPGIAPELRDKV---FERGvsTKGQGERGIGLALVRQSVE 81
|
90 100
....*....|....*....|
gi 896564911 401 HLGWTLQLQPCEPRGTRVTL 420
Cdd:cd16915 82 RLGGSITVESEPGGGTTFSI 101
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
168-400 |
4.88e-06 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 48.91 E-value: 4.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 168 AQHIAALRPGVQGQRIEVDPRGSSELHTIANALNDYLDRNEQFVERERV---------------FISTASHELRTPIAVM 232
Cdd:PRK13837 389 DRIVALLGLGRQRYGLRPPAGELQLLELALDCLAHAIERRRLETERDALerrleharrleavgtLASGIAHNFNNILGAI 468
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 233 TGAAELALEQPGLPERARQQMQRVLRTAQSVEQLIELLLVLARdpaRLAARAERIALDQLLPEIVDDHRHLLGDK-DLSI 311
Cdd:PRK13837 469 LGYAEMALNKLARHSRAARYIDEIISAGARARLIIDQILAFGR---KGERNTKPFDLSELVTEIAPLLRVSLPPGvELDF 545
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 312 GIQAAPVDIVAPLAVVQAAIGNLLRNAIENS-GRGHIELRLSSSAVLTLQDPGHG-MSPEEIAAIHArmargerADRGGG 389
Cdd:PRK13837 546 DQDQEPAVVEGNPAELQQVLMNLCSNAAQAMdGAGRVDISLSRAKLRAPKVLSHGvLPPGRYVLLRV-------SDTGAG 618
|
250
....*....|.
gi 896564911 390 IGLDLIARLCE 400
Cdd:PRK13837 619 IDEAVLPHIFE 629
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
328-422 |
7.68e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 44.76 E-value: 7.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 328 QAAIGNLLRNAI---ENSGRGHIELRLSSSAV-LTLQDPGHGMSPEEIAAIHARMARGE----RADRGGGIGLDLIARLC 399
Cdd:cd16946 6 QQLFVNLLENSLrytDTGGKLRIRAAQTPQEVrLDVEDSAPGVSDDQLARLFERFYRVEssrnRASGGSGLGLAICHNIA 85
|
90 100
....*....|....*....|...
gi 896564911 400 EHLGWTLQLQPCEPRGTRVTLDF 422
Cdd:cd16946 86 LAHGGTISAEHSPLGGLRLVLTL 108
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
331-421 |
9.57e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 44.41 E-value: 9.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 331 IGNLLRNAIENSGRGHIELRLS------SSAVL--TLQDPGHGMSPEEIAAIHARMARGE----RADRGGGIGLDLIARL 398
Cdd:cd16922 5 LLNLLGNAIKFTEEGEVTLRVSleeeeeDGVQLrfSVEDTGIGIPEEQQARLFEPFSQADssttRKYGGTGLGLAISKKL 84
|
90 100
....*....|....*....|...
gi 896564911 399 CEHLGWTLQLQPCEPRGTRVTLD 421
Cdd:cd16922 85 VELMGGDISVESEPGQGSTFTFT 107
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
327-421 |
1.65e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 43.60 E-value: 1.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 327 VQAAIGNLLRNAIENSG-----RGHIELR-LSSSAVLTLQDPGHGMSPEEIAAIHARMARGERADRGGGIGLDLIARLCE 400
Cdd:cd16976 1 IQQVLMNLLQNALDAMGkvenpRIRIAARrLGGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPVGKGTGLGLSISYGIVE 80
|
90 100
....*....|....*....|.
gi 896564911 401 HLGWTLQLQPCEPRGTRVTLD 421
Cdd:cd16976 81 EHGGRLSVANEEGAGARFTFD 101
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
188-420 |
2.06e-05 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 46.75 E-value: 2.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 188 RGSSELHTianaLNDYLDRNEQFVERERvfisTASHELRTPIAVMTGAAEL-----ALEQPGLPERARQQMQRVLRTAQS 262
Cdd:PRK15053 320 RSKDEIST----LNAQLTQIKQYVESLR----TLRHEHLNWMSTLNGLLQMkeydrVLEMVQGESQAQQQLIDSLREAFA 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 263 VEQLIELLLVLARDPARLAARAERIALDQL--LPEIVDDHRhllgdkdlsigiqaapvdivaplavVQAAIGNLLRNAIE 340
Cdd:PRK15053 392 DRQVAGLLFGKVQRARELGLKMVIVPGSQLsqLPPGLDSTE-------------------------FAAIVGNLLDNAFE 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 341 NS-----GRGHIELRLSSSA---VLTLQDPGHGMSPEEIAAIHARmARGERADRGG--GIGLDLIARLCEHLGWTLQLQP 410
Cdd:PRK15053 447 ASlrsdeGNKIVELFLSDEGddvVIEVADQGCGVPESLRDKIFEQ-GVSTRADEPGehGIGLYLIASYVTRCGGVITLED 525
|
250
....*....|
gi 896564911 411 CEPRGTRVTL 420
Cdd:PRK15053 526 NDPCGTLFSI 535
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
327-426 |
4.46e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 42.57 E-value: 4.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 327 VQAAIGNLLRNAIENS-GRGHIELRLS---SSAVLTLQDPGHGMSPEEIAAIHARMAR----GERADRGGGIGLDLIARL 398
Cdd:cd16952 1 LRSAFSNLVSNAVKYTpPSDTITVRWSqeeSGARLSVEDTGPGIPPEHIPRLTERFYRvdieRCRNTGGTGLGLAIVKHV 80
|
90 100
....*....|....*....|....*...
gi 896564911 399 CEHLGWTLQLQPCEPRGTRVTLDFGASR 426
Cdd:cd16952 81 MSRHDARLLIASELGKGSRFTCLFPSSR 108
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
330-421 |
5.43e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 42.05 E-value: 5.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 330 AIGNLLRNAIeNSGRGHIELR---LSSSAVLTLQDPGHGMSPEEIAAIHARMARGE--RADRGGGIGLDLIARLCEHLGW 404
Cdd:cd16950 4 VLSNLVDNAL-RYGGGWVEVSsdgEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDnaRGTSGTGLGLAIVQRISDAHGG 82
|
90
....*....|....*....
gi 896564911 405 TLQLQPCEPRG--TRVTLD 421
Cdd:cd16950 83 SLTLANRAGGGlcARIELP 101
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
333-420 |
5.81e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 42.02 E-value: 5.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 333 NLLRNAIEN-SGRGHIELRL---SSSAVLTLQDPGHGMSPEEIAAIHARMARGERADRGGGIGLDLIARLCEHLGWTLQL 408
Cdd:cd16943 10 NLLVNAAQAmEGRGRITIRTwahVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPVGEGTGLGLSLSYRIIQKHGGTIRV 89
|
90
....*....|..
gi 896564911 409 QPCEPRGTRVTL 420
Cdd:cd16943 90 ASVPGGGTRFTI 101
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
334-422 |
5.81e-05 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 42.59 E-value: 5.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 334 LLRNAIE----NSGRGHIELRLSSSA---VLTLQDPGHGMSPEEIAaiharmaRGERADRGGGIGLDLIARLCEHLGWTl 406
Cdd:COG2172 42 AVTNAVRhaygGDPDGPVEVELELDPdglEIEVRDEGPGFDPEDLP-------DPYSTLAEGGRGLFLIRRLMDEVEYE- 113
|
90
....*....|....*.
gi 896564911 407 qlqpCEPRGTRVTLDF 422
Cdd:COG2172 114 ----SDPGGTTVRLVK 125
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
223-422 |
7.37e-05 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 44.72 E-value: 7.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 223 HELRTPIAVMTGAaeLALEQPGlPERARQQMQRVLRTAQSVEQLIELLLVLARDparLAARAERIALDQLLPEIVDdhrh 302
Cdd:COG5805 296 HEIRNPLTSIKGF--LQLLQPG-IEDKEEYFDIMLSELDRIESIISEFLALAKP---QAVNKEKENINELIQDVVT---- 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 303 LLGDKDLSIGIQAApVDIVAPLAVVQA-------AIGNLLRNAIE---NSGRGHIELRLS-SSAVLTLQDPGHGMSPEEI 371
Cdd:COG5805 366 LLETEAILHNIQIR-LELLDEDPFIYCdenqikqVFINLIKNAIEampNGGTITIHTEEEdNSVIIRVIDEGIGIPEERL 444
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 896564911 372 AAIharmarGE----RADRGGGIGLDLIARLCE-HLGwTLQLQPCEPRGTRVTLDF 422
Cdd:COG5805 445 KKL------GEpfftTKEKGTGLGLMVSYKIIEnHNG-TIDIDSKVGKGTTFTITL 493
|
|
| PRK15041 |
PRK15041 |
methyl-accepting chemotaxis protein; |
137-266 |
9.15e-05 |
|
methyl-accepting chemotaxis protein;
Pssm-ID: 185001 [Multi-domain] Cd Length: 554 Bit Score: 44.56 E-value: 9.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 137 WVMLAGVIMIFVTVLMASFGMER-MVRPLSLLAQHIAALRPGVQGQRIEVDprGSSELHTIANALndyldRNEQfvereR 215
Cdd:PRK15041 194 WILVGVMIVVLAVIFAVWFGIKAsLVAPMNRLIDSIRHIAGGDLVKPIEVD--GSNEMGQLAESL-----RHMQ-----G 261
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 896564911 216 VFISTASHELRTPIAVMTGAAELALEQPGLPERARQQMQRVLRTAQSVEQL 266
Cdd:PRK15041 262 ELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQL 312
|
|
| marine_sort_HK |
TIGR03785 |
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is ... |
187-398 |
2.83e-04 |
|
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is paired with an adjacent response regulator (TIGR03787) gene. It co-occurs with a variant sortase enzyme (TIGR03784), usually in the same gene neighborhood, in proteobacterial species most of which are marine, and with an LPXTG motif-containing sortase target conserved protein (TIGR03788). Sortases and LPXTG proteins are far more common in Gram-positive bacteria, where sortase systems mediate attachment to the cell wall or cross-linking of pilin structures. We give this predicted sensor histidine kinase the gene symbol psdS, for Proteobacterial Dedicated Sortase system Sensor histidine kinase.
Pssm-ID: 163497 [Multi-domain] Cd Length: 703 Bit Score: 43.19 E-value: 2.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 187 PRGSSELHTIANALNDYLDRNEQFVERERVFISTASHELRTPIAVMTGAAELaLEQPGLPERARQQMQRvlrtAQSVEQL 266
Cdd:TIGR03785 458 SRSRDEIGDLSRSFAQMVARLRQYTHYLENMSSRLSHELRTPVAVVRSSLEN-LELQALEQEKQKYLER----AREGTER 532
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 267 IELLLVLARDPARL-----AARAERIALDQLLPEIVDDHRHLLGDKDLSIGIQAAPV--DIVAPLaVVQaAIGNLLRNAI 339
Cdd:TIGR03785 533 LSMILNNMSEATRLeqaiqSAEVEDFDLSEVLSGCMQGYQMTYPPQRFELNIPETPLvmRGSPEL-IAQ-MLDKLVDNAR 610
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 896564911 340 ENS-GRGHIELRLS---SSAVLTLQDPGHGMsPEEIAA-IHARMA--RGERADRGGGIGLDL-IARL 398
Cdd:TIGR03785 611 EFSpEDGLIEVGLSqnkSHALLTVSNEGPPL-PEDMGEqLFDSMVsvRDQGAQDQPHLGLGLyIVRL 676
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
311-409 |
3.36e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 40.19 E-value: 3.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 311 IGIQAAPVDIVAPLAVVQAAIGNLLRNAIENSGRGH---IELRLSSSAV-LTLQDPGHGMSPEEIAAIHARMARGE---- 382
Cdd:cd16947 5 INIPDRPIYANANTEALQRILKNLISNAIKYGSDGKflgMTLREDEKHVyIDIWDKGKGISETEKDHVFERLYTLEdsrn 84
|
90 100
....*....|....*....|....*..
gi 896564911 383 RADRGGGIGLDLIARLCEHLGWTLQLQ 409
Cdd:cd16947 85 SAKQGNGLGLTITKRLAESMGGSIYVN 111
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
223-369 |
4.37e-04 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 42.14 E-value: 4.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 223 HELRTPIAVMTGAAELALEQPGlPERARQQMQRVLRTAQSVEQLIELLLVLARDparlaARAERIALDqlLPEIVDDHRH 302
Cdd:COG3852 144 HEIRNPLTGIRGAAQLLERELP-DDELREYTQLIIEEADRLNNLVDRLLSFSRP-----RPPEREPVN--LHEVLERVLE 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 303 LLG-DKDLSIGIQaapVDIVAPLAVVQA-------AIGNLLRNAIE-NSGRGHIELRLSSS-------------AVLTLQ 360
Cdd:COG3852 216 LLRaEAPKNIRIV---RDYDPSLPEVLGdpdqliqVLLNLVRNAAEaMPEGGTITIRTRVErqvtlgglrprlyVRIEVI 292
|
....*....
gi 896564911 361 DPGHGMSPE 369
Cdd:COG3852 293 DNGPGIPEE 301
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
138-288 |
4.62e-04 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 42.31 E-value: 4.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 138 VMLAGVIMIFVTVLMASFGMERMVRPLSLLAQHIAALRPGVQGQRIEVDprGSSELHTIANALNDYLDRNEQFVERERVF 217
Cdd:COG0840 184 LAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVD--SKDEIGQLADAFNRMIENLRELVGQVRES 261
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 896564911 218 ---ISTASHELRTpiavmtGAAELAleqpglpERARQQMQRVLRTAQSVEQL---IELLLVLARDPARLAARAERIA 288
Cdd:COG0840 262 aeqVASASEELAA------SAEELA-------AGAEEQAASLEETAAAMEELsatVQEVAENAQQAAELAEEASELA 325
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
230-420 |
9.07e-04 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 40.76 E-value: 9.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 230 AVMTGAAELALEQPGLPERARQQMQRVLRTAQSVEQLIELLLVLARDPArlaarAERIALDQLLPEIVDDHRHLLGDK-D 308
Cdd:COG4585 71 AIKLQLEAARRLLDADPEAAREELEEIRELAREALAELRRLVRGLRPPA-----LDDLGLAAALEELAERLLRAAGIRvE 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 309 LSIGIQAAPVDIVAPLAVVqAAIGNLLRNAIENSGRGHIELRLSSSA---VLTLQDPGHGMSPEEIAaiharmargerad 385
Cdd:COG4585 146 LDVDGDPDRLPPEVELALY-RIVQEALTNALKHAGATRVTVTLEVDDgelTLTVRDDGVGFDPEAAP------------- 211
|
170 180 190
....*....|....*....|....*....|....*
gi 896564911 386 rGGGIGLDLIARLCEHLGWTLQLQPCEPRGTRVTL 420
Cdd:COG4585 212 -GGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRA 245
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
330-422 |
9.64e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 38.42 E-value: 9.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 330 AIGNLLRNAIENSGR-GHIELRL---SSSAVLTLQDPGHGMSPEEIAAIHARMARGE---RADRGGGIGLDLIARLCEHL 402
Cdd:cd16948 9 IIGQIVSNALKYSKQgGKIEIYSetnEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGEngrNFQESTGMGLYLVKKLCDKL 88
|
90 100
....*....|....*....|
gi 896564911 403 GWTLQLQPCEPRGTRVTLDF 422
Cdd:cd16948 89 GHKIDVESEVGEGTTFTITF 108
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
222-421 |
1.55e-03 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 40.54 E-value: 1.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 222 SHELRTPIAVMTGAAELALEQPGLPERARQQMQRVLRTAQSVEQLIELLLVLARdPARLAARAERIAldqllpEIVDDHR 301
Cdd:PRK10364 245 AHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVK-PTHLALQAVDLN------DLINHSL 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 302 HLLGDKDLSIGIQ----------AAPVDivaPLAVVQAAIgNLLRNAIENSGRG---HIELRLSSSAV-LTLQDPGHGMS 367
Cdd:PRK10364 318 QLVSQDANSREIQlrftandtlpEIQAD---PDRLTQVLL-NLYLNAIQAIGQHgviSVTASESGAGVkISVTDSGKGIA 393
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 896564911 368 PEEIAAIHAR--MARGEradrGGGIGLDLIARLCEHLGWTLQLQPCEPRGTRVTLD 421
Cdd:PRK10364 394 ADQLEAIFTPyfTTKAE----GTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLW 445
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
163-321 |
2.39e-03 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 40.34 E-value: 2.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 163 PLSLLAQHIAALRPGVQGQRIEVDPRGSSelhtianaLNDYLDR------------NEQFVERERVFIStaSHELRTPIA 230
Cdd:PRK10841 666 PLYGAQYPQKKGVEGLQGKRCWLAVRNAS--------LEQFLETllqrsgiqvqryEGQEPTPEDVLIT--DDPVQKKWQ 735
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 231 VmTGAAELALEQPGLPERarqqmQRVLRTAQSVEQLIELLLVLAR-----------DPARLAARAERIALDQLLPEIVDD 299
Cdd:PRK10841 736 G-RAVITFCRRHIGIPLE-----IAPGEWVHSTATPHELPALLARiyrielesddsANALPSTDKAVSDNDDMMILVVDD 809
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 896564911 300 H---RHLLGDKDLSIGIQAA---------------PVDIV 321
Cdd:PRK10841 810 HpinRRLLADQLGSLGYQCKtandgvdalnvlsknHIDIV 849
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
162-265 |
2.47e-03 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 40.00 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 162 RPLSLLAQHIAALRpgvQGQRIEVDPRGSSELHTIANALNDYLDRNEQFVERERVFISTASHELRTPIAVMtgaaelale 241
Cdd:PRK10815 217 RPIEALAKQVRELE---EGEREQLDPNPPRELTSLVRNLNRLLKNERERYTKYRTTLTDLTHSLKTPLAVL--------- 284
|
90 100
....*....|....*....|....*.
gi 896564911 242 qpglperarQQMQRVLRTAQ--SVEQ 265
Cdd:PRK10815 285 ---------QSTLRSLRSGKqmSVEQ 301
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
330-420 |
3.21e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 36.92 E-value: 3.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 330 AIGNLLRNAIENSgRGHIELRLSSSA---VLTLQDPGHGMSPEEIAAIHARMAR-GERADR---GGGIGLDLIARLCEHL 402
Cdd:cd16949 4 ALENVLRNALRYS-PSKILLDISQDGdqwTITITDDGPGVPEDQLEQIFLPFYRvDSARDResgGTGLGLAIAERAIEQH 82
|
90
....*....|....*...
gi 896564911 403 GWTLQLQPCEPRGTRVTL 420
Cdd:cd16949 83 GGKIKASNRKPGGLRVRI 100
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
204-420 |
3.54e-03 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 39.92 E-value: 3.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 204 LDRNEQfveRERVFISTASHELRTPIAVMTGAAElALEQPGLPERARQQMQRVLRTAQSVEQLIELLLVLAR-------- 275
Cdd:PRK10618 443 YEKNQQ---ARKAFLQNIGDELKQPLQSLAQLAA-QLRQTSDEEQQQPELDQLAEQSDVLVRLVDNIQLLNMletqdwkp 518
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 276 --DPARLAARAERIALDqLLPEIVDD-----HRHLLGDKDLSIGIQAAPVDIVAplavvqaaigNLLRNAIENSGRGHIE 348
Cdd:PRK10618 519 eqELFSLQDLIDEVLPE-VLPAIKRKglqllIHNHLKAEQLRIGDRDALRKILL----------LLLNYAITTTAYGKIT 587
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 349 LRLSSSA------VLTLQDPGHGMSPEEIAAIH---ARMARGERADRGGGIGLDLIARLCEHLGWTLQLQPCEPRGTRVT 419
Cdd:PRK10618 588 LEVDQDEsspdrlTIRILDTGAGVSIKELDNLHfpfLNQTQGDRYGKASGLTFFLCNQLCRKLGGHLTIKSREGLGTRYS 667
|
.
gi 896564911 420 L 420
Cdd:PRK10618 668 I 668
|
|
| AdeS_HK |
NF012226 |
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component ... |
123-234 |
3.67e-03 |
|
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component regulatory system for the AdeABC efflux pump can confer adaptive resistance to certain antibiotics, including tigecycline.
Pssm-ID: 411090 [Multi-domain] Cd Length: 353 Bit Score: 39.21 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 123 DISDFHDLEqfatrWVMLAGVIMiFVTVLMASFGM---ERMVRPLSLLAQHIAALRPGVQGQRIEVDPRGSSELHTIANA 199
Cdd:NF012226 50 DWTEFHFVD-----WIWLFTVIL-CGSVISLIIGMklaQRFIVPINFLADAAKKISQGDLSARAEDSQIHSAEISELMHN 123
|
90 100 110
....*....|....*....|....*....|....*
gi 896564911 200 LNDYLDRNEQFVERERVFISTASHELRTPIAVMTG 234
Cdd:NF012226 124 FNDMAQKLESSVKNAQVWNAAIAHELRTPITILQG 158
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
286-422 |
3.99e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 37.40 E-value: 3.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 286 RIALDQLLPEIVDDHrhllGDKDLSIGIQA----APVDIVAPLAVVqaaIGNLLRNAIEN--SGR--GHIELRLSSSAV- 356
Cdd:cd16951 2 GEYINRIASAINAIH----AVGDIRINITGdtgpVSSEVATAIGLV---VNELLQNALKHafSDRegGTITIRSVVDGDy 74
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 896564911 357 --LTLQDPGHGMsPEeiaaiharmarGERADRGGGIGLDLIARLCEHLGWTLQLQPCEPRGTRVTLDF 422
Cdd:cd16951 75 lrITVIDDGVGL-PQ-----------DEDWPNKGSLGLQIVRSLVEGELKAFLEVQSAENGTRVNIDI 130
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
222-392 |
4.30e-03 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 39.19 E-value: 4.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 222 SHELRTPIAVMTGAAELAleQPGLPERARQQMQRVLRTAQSVEQLIELLLVLARdpaRLAARAERIALDQLLPEIVDdhr 301
Cdd:COG5809 278 AHEIRNPLTSLKGFIQLL--KDTIDEEQKTYLDIMLSELDRIESIISEFLVLAK---PQAIKYEPKDLNTLIEEVIP--- 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 302 hLLGDKDLS--IGIQAAPVDIVAPLAVV-----QAAIgNLLRNAIENSGRG---HIELRL--SSSAVLTLQDPGHGMSPE 369
Cdd:COG5809 350 -LLQPQALLknVQIELELEDDIPDILGDenqlkQVFI-NLLKNAIEAMPEGgniTIETKAedDDKVVISVTDEGCGIPEE 427
|
170 180
....*....|....*....|....*..
gi 896564911 370 EIAAIharmarGE----RADRGGGIGL 392
Cdd:COG5809 428 RLKKL------GEpfytTKEKGTGLGL 448
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
63-398 |
7.68e-03 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 38.70 E-value: 7.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 63 PHYRWQDSDTLSLYRFDAVNLPDSLRTLHPGLHDGVMVKGRETAVMVRETQSMGRVALVLDISDFHDLEQFATRWVMLAG 142
Cdd:COG3321 864 PTYPFQREDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALL 943
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 143 VimifVTVLMASFGMERMVRPLSLLAQHIAALRPGVQGQRIEVDPRGSSELHTIANALNDYLDRNEQFVERERVFISTAS 222
Cdd:COG3321 944 A----LAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAA 1019
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 223 HELRTPIAVMTGAAELALEQPGLPERARQQMQRVLRTAQSVEQLIELLLVLARDPARLAARAERIALD-QLLPEIVDDHR 301
Cdd:COG3321 1020 ALLALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAaALAAAALALAL 1099
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 302 HLLGDKDLSIGIQAAPVDIVAPLAVVQAAIGNLLRNAIENSGRGHIELRLSSSAVLTLQDPGHGMSPEEIAAIHARMARG 381
Cdd:COG3321 1100 AALAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALAL 1179
|
330
....*....|....*..
gi 896564911 382 ERADRGGGIGLDLIARL 398
Cdd:COG3321 1180 ALAAALAAALAGLAALL 1196
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
330-420 |
7.70e-03 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 35.71 E-value: 7.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 896564911 330 AIGNLLRNAIENSGR----GHIELRLSSSA---VLTLQDPGHGMSPEEIAaiharmaRGERADRGGGIGLDLIARLCEHL 402
Cdd:cd16936 4 AVSEAVTNAVRHAYRhdgpGPVRLELDLDPdrlRVEVTDSGPGFDPLRPA-------DPDAGLREGGRGLALIRALMDEV 76
|
90
....*....|....*...
gi 896564911 403 GWTlqlqpCEPRGTRVTL 420
Cdd:cd16936 77 GYR-----RTPGGKTVWL 89
|
|
| |
