|
Name |
Accession |
Description |
Interval |
E-value |
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
28-655 |
4.44e-81 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 270.16 E-value: 4.44e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 28 LDEVEVRGHYDNAVGSSDAASEGKVNASLIKNRPISRVGEIMEFVPGMIVTQHSGSgkANQFYLRGFNlDHGTDFATYVD 107
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGG--AGQISIRGFG-GGGNRVLVLVD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 108 DMPVNMRTHahgqGYTDLNFLIPELVSHIHYKKGPYSAEEGDFSSAGAARLHLLNQL--PQGIASLTVGSYDYQRMLLan 185
Cdd:COG1629 78 GVPLNDPSG----GDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKdgKGGEVSASYGSYGTYRASL-- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 186 SVAVADGHLLYALDVNHYDGP-WQVAEGVKKYN--GVLRYSEGDAHdSMTLTAMAYHNRWSSTDQIPLRAVRSGQI---G 259
Cdd:COG1629 152 SLSGGNGKLAYRLSASYRDSDgYRDNSDSDRYNlrAKLGYQLGDDT-RLTLSASYSDSDQDSPGYLTLAALRPRGAmddG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 260 RFDAIDPTDGGDSSRYSLSFNKQHRDQHGGWQMSAYAVRSELDLYSNFTYLKDDPINGDQFNQseKRTMLGVNLSKSWLG 339
Cdd:COG1629 231 TNPYSNDTDDNTRDRYSLSLEYEHLGDGLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQTDF--DNRTYGLELRLTYDL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 340 ELaGLPMENKLGVQTRYDKL---SPVALYNTAQKQRLSLIRSDMVEESSAGLYAENTVWWHEKLRTVAGLRYDRYQFDVK 416
Cdd:COG1629 309 GF-GGKHTLLVGLDYQRQDLdgsGYPLDLGSGSLPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDVD 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 417 SSING---NSGNKGDGITSPKLSVIFGPWANTEFFYNIGKGFHSND-----ARGTTQTLLPNGNpASPVTplvgTRGSEV 488
Cdd:COG1629 388 DTVTGtdsASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTfgelyANGTDPYSVGNPD-LKPET----STNYEL 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 489 GMRTEWIPG-LQSSLAIWQLDIDSELVFVGDAGE------TEPSRASRRYGVEWNNHYVVNDWLLLDMDLALSKARFT-- 559
Cdd:COG1629 463 GLRYRLLDGrLSLSLALFYSDVDNEILSVPLPNDsgfstyYTNAGKARSYGVELELSYQLTPGLSLNASYSYTDAKFDdd 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 560 ---HTDPAGQYIPGAINKVASLGATVTNWGNWFGSVQLRYFGPRPLVEDNSVRSNSTFLTY-ARVGYRYNPRTTFTLDVF 635
Cdd:COG1629 543 tdgSADLDGNRLPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANTQGAPGGYTLVdLGAGYRFGDNLTLSLGVD 622
|
650 660
....*....|....*....|
gi 902768162 636 NLFDRKASDIDYYYESQLAG 655
Cdd:COG1629 623 NLFDKKYATSLSVRASNVRG 642
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
52-681 |
2.40e-42 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 162.62 E-value: 2.40e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 52 VNASLIKNRPISRVGEIMEFVPGMIVTQHSGSGkANQFYLRGFNLDhgtDFATYVDDMPVNMRThahGQGYTDLNFLIPE 131
Cdd:cd01347 5 ITAEDIEKQPATSLADLLRRIPGVSVTRGGGGG-GSTISIRGFGPD---RTLVLVDGLPLASSN---YGRGVDLNTIPPE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 132 LVSHIHYKKGPYSAEEGDFSSAGAARLHLLNQLPQGIASLTVGSYDYQRMLLAN-----SVAVA-DGHLLYALDVNHYDG 205
Cdd:cd01347 78 LIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSGGggfdvSGALAdDGAFGARLYGAYRDG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 206 PWQVA-------EGVKKYN--GVLRYSEGDAHdSMTLTAMAYHNR-----WSSTDQIPLRAVRSGQIGRFDAIDPTDGGD 271
Cdd:cd01347 158 DGTIDgdgqaddSDEERYNvaGKLDWRPDDDT-RLTLDAGYQDQDadgpgGTLPANGTGSSLGGGPSSNTNGDRDWDYRD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 272 SSRYSLSFNKQHRDQHGGWQMSAYAV--RSELDLYSNFTYLKDDPINGDQFN--QSEKRTMLGVNLSKSWLGELAGLPME 347
Cdd:cd01347 237 RYRKRASLGLEHDLNDTGWTLRANLSysYTDNDGDPLILNGGNNAAGGDLGRsgYSSERDTTQLGFDAGLNAPFGTGPVA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 348 NKL--GVQTRYDKLspvalyntaqkqrlslirsdmvEESSAGLYAENTVWWHEKLRTVAGLRYDRYQFDVKSSINGNSGN 425
Cdd:cd01347 317 HTLtlGVEYRREEL----------------------DEKQTALYAQDTIELTDDLTLTLGLRYDHYDQDSKDTIAGGTTA 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 426 KGDGIT-SPKLSVIFGPWANTEFFYNIGKGFHSNDARGTTQTLLPNGNPASPVTPLVGTRGS--EVGMRTEWIPGLQSSL 502
Cdd:cd01347 375 KKSYSHwSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAAVGNPNLKPEKSKqyELGLKYDPGDGLTLSA 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 503 AIWQLDIDSELVFVGDAGETEPSRAS------RRYGVEWNNHYVVNDWLLLDMDLALSKARFTHTDPA--GQYIPGAINK 574
Cdd:cd01347 455 ALFRIDIKNEIVSTPTNTGLGLVTVYvnggkaRIRGVELEASYDLTDGLGLTGSYTYTDTEVKRTDGAttGNRLPGIPKH 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 575 VASLGATVT-NWGNWFGSVQLRYFGPRPLVE---DNSVRSNSTFLTYARVGYRYNPRTTFTLDVFNLFDRKASDIDYYYE 650
Cdd:cd01347 535 TANLGLDYElPDEGLTAGGGVRYRGKQYADTangNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSVRG 614
|
650 660 670
....*....|....*....|....*....|.
gi 902768162 651 SQLAGeatpvndkhfHPVEPRSARLTVTYNF 681
Cdd:cd01347 615 SGLYG----------YYGPGRTYYLSVSYKF 635
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
216-680 |
8.24e-21 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 95.99 E-value: 8.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 216 YNGVLRYSEGDAHDSMTLTAMAYHNRWSSTDQIPLRAVRSGQIGRFDAI--DPTDGGDSSRYSLSFNKQHRDQHG-GWQM 292
Cdd:pfam00593 2 WQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYygRDYSDTDRKRLSLGYDYDLGDGLSwLSTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 293 SAYAVRSELDLYSNFTYLKDDPiNGDQFNQSEKRTMLGVNLSKSWLGELAGLPM--ENKLGVQTRYDKLSPVALYNTAQK 370
Cdd:pfam00593 82 RLGLRYSSLDGDYTSNSSGLSG-AGDYLSDDRLYGLYGLDGDLELSLDLSHDLLlgVELRTAGLDYRRLDDDAYDPYDPA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 371 QRLSLIRSDmVEESSAGLYAENTVWWHEKLRTVAGLRYDRYQFDVKSS-INGNSGNKGDGITSPKLSVIFGPWANTEFFY 449
Cdd:pfam00593 161 NPSSSSYSD-TTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGnGGGDNFSRSYSAFSPRLGLVYKPTDNLSLYA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 450 NIGKGFH-------SNDARGTTQTLLPNGNPA-SPVTplvgTRGSEVGMRTEWiPGLQSSLAIWQLDIDSELVFVGDAGE 521
Cdd:pfam00593 240 SYSRGFRapslgelYGSGSGGGGGAVAGGNPDlKPET----SDNYELGLKYDD-GRLSLSLALFYIDIKNLITSDPDGPG 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 522 TEPSR-------ASRRYGVEWNNHYvvNDWllldmDLALSKARFTHTD--------PAGQYIPGAINKVASLGAT-VTNW 585
Cdd:pfam00593 315 LGGTVytytnvgKARIRGVELELSG--RLW-----GLGLSGGGYTYTDadddadadDTGNPLPNVPRHTANLGLTyDFPL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 586 GNWFGSVQLRYFGPRPLV---EDNSVRSNSTFLTYARVGYRYNPRTTFTLDVFNLFDRKASDIDYYYESQLAGeatpvnd 662
Cdd:pfam00593 388 GGWGARLGARYVGSGERRygdAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGGGNLGG------- 460
|
490
....*....|....*...
gi 902768162 663 khfHPVEPRSARLTVTYN 680
Cdd:pfam00593 461 ---YPGPGRTFYLGLSYK 475
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
57-681 |
2.73e-19 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 92.09 E-value: 2.73e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 57 IKNRPISRVGEIMEFVPGMIVTQHSGSGKANQFYLRGFNLdhgtdfATYVDDMPVN-MRTHAHGQgytdlNFLI-PELVS 134
Cdd:TIGR01783 14 LEDQQAGSLSEALQRVPGVVVGGSGGTTQFGNITIRGFGL------EVDIDNVYLDgVPLLSRGN-----LAIVdPAMVE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 135 HIHYKKGPYSAEEGDFSSAGAarlhlLN-------QLPQGIASLTVGSYDYQRMLLANSVAV-ADGHLLYALDVNHYDGP 206
Cdd:TIGR01783 83 RVEVLRGPASLLYGGSAPGGV-----INivtkrpqDEPKGSVTFGAGTRSGYRTAFDLGGPLgADGTFRGRLNGARQDGD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 207 WQVAEGVKKYNGVLRYSEGDAHDSMTLTAMAYHNRWSSTDQ---IPLRAVRSGQIGRFDAI------DPTDGGDSSRYSL 277
Cdd:TIGR01783 158 SFYDGAGEETRLGATATDWQLDDRTLLRLGAYYQKERDRGGyggLPASGGTSGRDLSSDRYlgtssnRNYDDREYLSYGL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 278 SFNKQHRDqhgGWQMSAYAVRSELDLYSNFTYL-------KDDPINGDQFNQSEKRTMLGVNLSkswlGELAGLPMENKL 350
Cdd:TIGR01783 238 SLEYQFND---VWTGKQNLRYSYFDTDSNQVQAsgyssdgGLFGRSLTVVNVKQDRVQIDAGLD----GEFETGPIEHDL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 351 GVQTRYDKLSPVALYNTAQ-------KQRLSLIRSDMVEESSA----------GLYAENTVWWHEKLRTVAGLRYDRYQF 413
Cdd:TIGR01783 311 LLGVSYGQRTTNRFNNTGYpsdniysLTATSSARTDIGDSPKDralssttkalNGVALQRILLADKWTLTLGGRYDSVDV 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 414 DVKSSINGNSGNKGDGITSPKLSVIFGPWANTEFFYNIGKGFHSNDARGTTQTLlpNGNPASPVTplvgTRGSEVGMRTE 493
Cdd:TIGR01783 391 KSNNGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGN--SGDILEPEK----GKNYELGVRYD 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 494 WIPGLQSSLAIWQLDIDSELVfVGDAGETEPSRASRR--YGVEWNNHYVVNDWLLLDMDLALSKARFTHT---DPAGQYI 568
Cdd:TIGR01783 465 LGDSLLATAALFRITKDNQLV-QDPVNGTFSVNAGKTrnRGVELEARGYLTPGLSLSAGYTYTDAEFTEDtngDTQGNTV 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 569 PGAINKVASLGAT---VTNWGNWFGSVQLRYFGPRPLVEDNSVRSNSTFLTYARVGYRYNPRTTFTLDVF--NLFDRkas 643
Cdd:TIGR01783 544 PFVPKHTASLWASyapPVGDNGLTLGGGVQYTGKAYVDGGNTGKVPSYTVVDLSVRYDLTKKKNLTLALNvnNLFDR--- 620
|
650 660 670
....*....|....*....|....*....|....*...
gi 902768162 644 diDYYYESQLAGeatpvNDKHFHPVEPRSARLTVTYNF 681
Cdd:TIGR01783 621 --DYYTSGYRWG-----PSAYIYPGAPRTVGLSVSYDF 651
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
28-655 |
4.44e-81 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 270.16 E-value: 4.44e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 28 LDEVEVRGHYDNAVGSSDAASEGKVNASLIKNRPISRVGEIMEFVPGMIVTQHSGSgkANQFYLRGFNlDHGTDFATYVD 107
Cdd:COG1629 1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGG--AGQISIRGFG-GGGNRVLVLVD 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 108 DMPVNMRTHahgqGYTDLNFLIPELVSHIHYKKGPYSAEEGDFSSAGAARLHLLNQL--PQGIASLTVGSYDYQRMLLan 185
Cdd:COG1629 78 GVPLNDPSG----GDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKdgKGGEVSASYGSYGTYRASL-- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 186 SVAVADGHLLYALDVNHYDGP-WQVAEGVKKYN--GVLRYSEGDAHdSMTLTAMAYHNRWSSTDQIPLRAVRSGQI---G 259
Cdd:COG1629 152 SLSGGNGKLAYRLSASYRDSDgYRDNSDSDRYNlrAKLGYQLGDDT-RLTLSASYSDSDQDSPGYLTLAALRPRGAmddG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 260 RFDAIDPTDGGDSSRYSLSFNKQHRDQHGGWQMSAYAVRSELDLYSNFTYLKDDPINGDQFNQseKRTMLGVNLSKSWLG 339
Cdd:COG1629 231 TNPYSNDTDDNTRDRYSLSLEYEHLGDGLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQTDF--DNRTYGLELRLTYDL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 340 ELaGLPMENKLGVQTRYDKL---SPVALYNTAQKQRLSLIRSDMVEESSAGLYAENTVWWHEKLRTVAGLRYDRYQFDVK 416
Cdd:COG1629 309 GF-GGKHTLLVGLDYQRQDLdgsGYPLDLGSGSLPTLTSGADDDGTTTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDVD 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 417 SSING---NSGNKGDGITSPKLSVIFGPWANTEFFYNIGKGFHSND-----ARGTTQTLLPNGNpASPVTplvgTRGSEV 488
Cdd:COG1629 388 DTVTGtdsASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTfgelyANGTDPYSVGNPD-LKPET----STNYEL 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 489 GMRTEWIPG-LQSSLAIWQLDIDSELVFVGDAGE------TEPSRASRRYGVEWNNHYVVNDWLLLDMDLALSKARFT-- 559
Cdd:COG1629 463 GLRYRLLDGrLSLSLALFYSDVDNEILSVPLPNDsgfstyYTNAGKARSYGVELELSYQLTPGLSLNASYSYTDAKFDdd 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 560 ---HTDPAGQYIPGAINKVASLGATVTNWGNWFGSVQLRYFGPRPLVEDNSVRSNSTFLTY-ARVGYRYNPRTTFTLDVF 635
Cdd:COG1629 543 tdgSADLDGNRLPGVPPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANTQGAPGGYTLVdLGAGYRFGDNLTLSLGVD 622
|
650 660
....*....|....*....|
gi 902768162 636 NLFDRKASDIDYYYESQLAG 655
Cdd:COG1629 623 NLFDKKYATSLSVRASNVRG 642
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
7-681 |
3.81e-45 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 171.65 E-value: 3.81e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 7 MSLALVGLFASMPSYATE-TVDLDEVEVRGHYDNAVGSSD-AASEGKVNASLIKNRPISRVGEIMEFVPGMIVTQHSGSG 84
Cdd:COG4772 1 MRRALAAALLLAAAAAAEaATTLETVVVTGSRAAEARLKDvPGSVSVVDREELENQAATSLREVLRRVPGVNVQEEDGFG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 85 KANQFYLRGFNLDHGTDFATYVDDMPVNMRTHAHGQGYTdlnFLIPELVSHIHYKKGPYSAEEGDFSSAGAarlhlLN-- 162
Cdd:COG4772 81 LRPNIGIRGLGPRRSRGITLLEDGIPIAPAPYGDPAAYY---FPDLERMERIEVLRGAAALRYGPQTVGGA-----INfv 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 163 -----QLPQGIASLTVGSYDYQRmlLANSVAVADGHLLYALDVNHY--DGpWQVAEGVKKYNGVLR-------------- 221
Cdd:COG4772 153 trtipTAFGGELRVTGGSFGYRR--THASVGGTVGNFGYLVEYSRKrgDG-FRDNSGFDINDFNAKlgyrlsdrqeltlk 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 222 --YSEGDAHDSMTLT-AMAYHNRWSSTdqiplravrsgqiGRFDAIDptdgGDSSRYSLSFNKQHRDQHggwQMSAYAVR 298
Cdd:COG4772 230 fqYYDEDANTPGGLTdAQFDADPRQSY-------------RPADQFD----TRRTQLSLRYEHQLSDNT---TLTTTAYY 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 299 SELDLYSNFTYLKDDPINGDQFNQSEKRT--MLGVNLSKSWLGELAGlpMENKLGVQTRY-----DKLSPVALYNTAQKQ 371
Cdd:COG4772 290 NDFSRNWYIRQNTADPNTPGLGLRGNPRGyrSYGIEPRLTHRFELGG--VPHTLEVGLRYhreeeDRKQYVNTYGQGRSG 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 372 RLSliRSDMVEESSA-GLYAENTVWWHEKLRTVAGLRYDRYQFDVKSSINGNSGNKGDG-----ITSPKLSVIFGPWANT 445
Cdd:COG4772 368 AGL--RRDRRFSADAlAAYAQNRFELTGRLTLTPGLRYEHIRRDRTDRYSTRTGGDDSGsnsysEFLPGLGLLYQLTDNL 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 446 EFFYNIGKGFHSNdargTTQTLLPNGNPASPVTPLVGTrGSEVGMRTEWIPGLQSSLAIWQLDIDSELVFVGDAGETEPS 525
Cdd:COG4772 446 QLYANVSRGFEPP----TFGDLAYGNGGNPDLKPEKSW-NYELGTRGRIGNGLSAEVALFYIDYDNELGSCSAAGGDRST 520
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 526 R----ASRRYGVE----WNNHYVVNDWLLLDMDLALSKARFTHT---DPAGQYIPGAINKVASLGATVTnWGNWFGSVQL 594
Cdd:COG4772 521 FtnagETRHQGLElaldYDLLKGGGLGLPLFAAYTYTDAEFTSDfgpVFAGNRLPYVPRHQLTAGLGYE-HGGWTANLNG 599
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 595 RYFGPRPLVEDNSVRSNSTFLT--Y----ARVGYRYNPRTTFTLDVFNLFDRKasdidyYYESqlageATPVNDKHFHPV 668
Cdd:COG4772 600 RYVSEQFTDAANTVADGSFGKIpsYtvldLSASYDFGKNLSLFAGVNNLFDKR------YIAS-----RAPNYAAGIRPG 668
|
730
....*....|...
gi 902768162 669 EPRSARLTVTYNF 681
Cdd:COG4772 669 PPRTVYAGLRLKF 681
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
52-681 |
2.40e-42 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 162.62 E-value: 2.40e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 52 VNASLIKNRPISRVGEIMEFVPGMIVTQHSGSGkANQFYLRGFNLDhgtDFATYVDDMPVNMRThahGQGYTDLNFLIPE 131
Cdd:cd01347 5 ITAEDIEKQPATSLADLLRRIPGVSVTRGGGGG-GSTISIRGFGPD---RTLVLVDGLPLASSN---YGRGVDLNTIPPE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 132 LVSHIHYKKGPYSAEEGDFSSAGAARLHLLNQLPQGIASLTVGSYDYQRMLLAN-----SVAVA-DGHLLYALDVNHYDG 205
Cdd:cd01347 78 LIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSGGggfdvSGALAdDGAFGARLYGAYRDG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 206 PWQVA-------EGVKKYN--GVLRYSEGDAHdSMTLTAMAYHNR-----WSSTDQIPLRAVRSGQIGRFDAIDPTDGGD 271
Cdd:cd01347 158 DGTIDgdgqaddSDEERYNvaGKLDWRPDDDT-RLTLDAGYQDQDadgpgGTLPANGTGSSLGGGPSSNTNGDRDWDYRD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 272 SSRYSLSFNKQHRDQHGGWQMSAYAV--RSELDLYSNFTYLKDDPINGDQFN--QSEKRTMLGVNLSKSWLGELAGLPME 347
Cdd:cd01347 237 RYRKRASLGLEHDLNDTGWTLRANLSysYTDNDGDPLILNGGNNAAGGDLGRsgYSSERDTTQLGFDAGLNAPFGTGPVA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 348 NKL--GVQTRYDKLspvalyntaqkqrlslirsdmvEESSAGLYAENTVWWHEKLRTVAGLRYDRYQFDVKSSINGNSGN 425
Cdd:cd01347 317 HTLtlGVEYRREEL----------------------DEKQTALYAQDTIELTDDLTLTLGLRYDHYDQDSKDTIAGGTTA 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 426 KGDGIT-SPKLSVIFGPWANTEFFYNIGKGFHSNDARGTTQTLLPNGNPASPVTPLVGTRGS--EVGMRTEWIPGLQSSL 502
Cdd:cd01347 375 KKSYSHwSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGTAAVGNPNLKPEKSKqyELGLKYDPGDGLTLSA 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 503 AIWQLDIDSELVFVGDAGETEPSRAS------RRYGVEWNNHYVVNDWLLLDMDLALSKARFTHTDPA--GQYIPGAINK 574
Cdd:cd01347 455 ALFRIDIKNEIVSTPTNTGLGLVTVYvnggkaRIRGVELEASYDLTDGLGLTGSYTYTDTEVKRTDGAttGNRLPGIPKH 534
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 575 VASLGATVT-NWGNWFGSVQLRYFGPRPLVE---DNSVRSNSTFLTYARVGYRYNPRTTFTLDVFNLFDRKASDIDYYYE 650
Cdd:cd01347 535 TANLGLDYElPDEGLTAGGGVRYRGKQYADTangNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSVRG 614
|
650 660 670
....*....|....*....|....*....|.
gi 902768162 651 SQLAGeatpvndkhfHPVEPRSARLTVTYNF 681
Cdd:cd01347 615 SGLYG----------YYGPGRTYYLSVSYKF 635
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
5-681 |
1.60e-38 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 151.97 E-value: 1.60e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 5 SGMSLALVG---LFASMPSYATETVDLDEVEVRGHYDNAVG--SSDAASEGKVNASL--------------IKNRPISRV 65
Cdd:COG4773 6 AGSGLAAAAagaLAQAAAAAAAEATTLPEVTVTGTAEGTGGytAKSSSTATKLDTPLretpqsvsvvtrqlIEDQGATTL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 66 GEIMEFVPGMIVTQHSGSGkANQFYLRGFNLDhgtdfATYVDDMPVNmrthAHGQGYTDLNFL--IpELVshihykKGPY 143
Cdd:COG4773 86 DDALRNVPGVTVSSYDGGG-RDSFSIRGFSID-----NYLRDGLPLG----GFGGGQPDTANLerV-EVL------KGPA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 144 SAEEGdFSSAGAarlhLLN-------QLPQGIASLTVGSYDYQRMLL-ANSVAVADGHLLYALDVNHYDG-PWQVAEGVK 214
Cdd:COG4773 149 GLLYG-AGSPGG----LVNlvtkrptAEPQGEVSLSAGSWDTYRATAdVGGPLNEDGTLRYRLNAAYEDGdSFRDGVDNR 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 215 KY--NGVLRYsegDAHDSMTLTAMAYHNRWSSTDQIPLRAVRSGQIG----RFDAiDPTDGGDSSRYSLSFNKQHR-DQH 287
Cdd:COG4773 224 RTliAPSLDW---DLTDDTTLTLGAEYQDDDSTGDRGFLPLDGTLLDlprsTNLG-EPWDYYDTETTTLFAELEHRfNDD 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 288 GGWQMSAYAVRSELDLYSNFTYLKDDPINGD----QFNQSEKRTMLGVNLSKSwlGELAGLPMENKL--GV---QTRYDK 358
Cdd:COG4773 300 WSLRANARYSDSDRDGRSAYAYGAPDAATGTltryASARDGDSRSDSLDANLN--GKFETGGLEHTLlvGAdysRYDSDS 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 359 LSPVAL--------YNTAQKQRLSLIRSDMVEESSaGLYAENTVWWHEKLRTVAGLRYDRYQFDVKSSINGNSGNKGDGI 430
Cdd:COG4773 378 DSATAGtiniynpvYGNLPEPDFDASDTDTTTRQT-GLYAQDQISLTDRLSLLLGGRYDWYETDSTNRLGGSTTSYDDSA 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 431 TSPKLSVIFGPWANTEFFYNIGKGFHSNDARGTtqtllpNGNPASPVTplvgTRGSEVGMRTEWIPG-LQSSLAIWQLDI 509
Cdd:COG4773 457 FTPRAGLVYDLTPGLSLYASYSESFEPQSGADN------NGNPLDPET----GKQYEAGVKGELFDGrLNATLAVFDITQ 526
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 510 DSelVFVGDAGETEPSRAS---RRYGVEWNNHYVVNDWLLLDMDLALSKARFTHTDPA--GQYIPGAINKVASLGATVT- 583
Cdd:COG4773 527 KN--VATTDPDNPNFYVQVgevRSRGVELELSGELTPGLNLIAGYTYTDAKITKDADAleGKRLTNVPRHTASLWTTYRf 604
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 584 ---NWGNWFGSVQLRYFGPRPLVEDNSVRSNSTFLTYARVGYRYNPRTTFTLDVFNLFDRKasdidyYYESQLAGEATPV 660
Cdd:COG4773 605 psgALKGLGLGGGVRYVGERYGDAANTFTLPSYTLVDAGARYDLGKNWTLQLNVNNLFDKK------YYASSGSRGYVYY 678
|
730 740
....*....|....*....|.
gi 902768162 661 NdkhfhpvEPRSARLTVTYNF 681
Cdd:COG4773 679 G-------APRNVRLSLSYKF 692
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
52-681 |
2.41e-38 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 151.18 E-value: 2.41e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 52 VNASLIKNRPISRVGEIMEFVPGmIVTQHSGSGKANQFYLRGFNldhgTDFATYVDDMPVNmrthahGQGYTDLNFL--I 129
Cdd:COG4774 16 VTRELIEDQGATSLADALRNVPG-VTFGAGEGGNGDSFSIRGFS----ASGDIYVDGLRDP------GQYRRDTFNLerV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 130 pELVshihykKGPYSAEEGDFSSAGAarlhlLNQL-------PQGIASLTVGSYDYQRMLLANSVAVADGhLLYALDVNH 202
Cdd:COG4774 85 -EVL------KGPASVLYGRGSPGGV-----INLVtkrptdePFTEVTLTYGSDGQRRATLDVNGPLGDD-LAYRLNGMY 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 203 YDGPWQVAEGVKKYNGV---LRYSEGDAHdsmTLTAMAYHNRwssTDQIPLRAVRSGQIGRFDAIDPtdggdSSRYSLSF 279
Cdd:COG4774 152 RDSDSYRDGVDNDRWGIapsLTWRLGDRT---RLTLDYEYQD---DDRTPDYGVPAVANGRPVDVDR-----STFYGQPD 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 280 NKQHRDQHGG-----------WQMSAYAVRSELDLYSNFTYLKDDPINGD----QFNQSEKRTMLGVNLSksWLGELAGL 344
Cdd:COG4774 221 DYSDSETDSAtlrlehdfndnWTLRNALRYSDYDRDYRNTYPTGGNATGTvtrsAYRRDQDNDTLSNQTD--LTGKFDTG 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 345 PMENKL--GVQTRYDK-----------LSPVALYN---TAQKQRLSLIRSDMVEES-SAGLYAENTVWWHEKLRTVAGLR 407
Cdd:COG4774 299 GVKHTLlaGVEYSREDsdnarysgggtAPTVNLYNpvyGAPVTGPTLGGADNDSRTdTTGLYLQDTISLTDRWSLLAGLR 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 408 YDRYQFDVKSSINGN-SGNKGDGITSPKLSVIFGPWANTEFFYNIGKGFhsnDARGTTQTLLPNGNPASPVTplvgTRGS 486
Cdd:COG4774 379 YDRFDTDYTDRTTGAtTSSYDDSAFSPRAGLVYKPTPNLSLYASYSTSF---NPGGGAPSLSNAGQALDPEK----SRQY 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 487 EVGMRTEWIPG-LQSSLAIWQLDIDSELVF-VGDAGETEPSRASRRYGVEWNNHYVVNDWLLLDMDLALSKARFTHT--- 561
Cdd:COG4774 452 EVGVKWDLLDGrLSLTAALFRIEKTNVRTTdPANPGVYVQTGEQRSRGVELEATGELTPGWSVLAGYTYLDAEITKSana 531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 562 DPAGQYIPGAINKVASLGATVT-NWGNWFGSVQLRYFGPRPLVEDNSVRSNSTFLTYARVGYRYNPRTTFTLDVFNLFDR 640
Cdd:COG4774 532 ANVGNRLPNVPRHSASLWTTYDlPLPGLTLGGGVRYVGSRYADAANTVKLPSYTRFDAGASYRLNKNLTLRLNVNNLTDK 611
|
650 660 670 680
....*....|....*....|....*....|....*....|.
gi 902768162 641 KasdidyYYESqlageATPVNdkHFHPVEPRSARLTVTYNF 681
Cdd:COG4774 612 R------YYAS-----AYGSG--YVTPGAPRTVLLSASYRF 639
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
7-631 |
1.34e-35 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 142.69 E-value: 1.34e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 7 MSLALVGLFASMPSYATETVDLDEVEVRGHYDNAVGSSDAASEGKVNASLIKNRPISRVGEIMEFVPGMIVTQHSGSGKA 86
Cdd:COG4771 6 LLLLLALAAQAADALAEDATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRSGGRGGS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 87 NQFYLRGFNldhGTDFATYVDDMPVNMRTHAhgqGYTDLNFLIPELVSHIHYKKGPYSAEEGDFSSAGAARLHLL--NQL 164
Cdd:COG4771 86 SGISIRGLG---GDRVLVLIDGVPVNNPALG---GGGDLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKkpTDE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 165 PQGIASLTVGSYDYQRMLLANSVAVADGHLLYALDVNHYD---------GPWQVAEGVKKYNGVLRYS-EGDAHDSMTLT 234
Cdd:COG4771 160 LEGSVSLGYGSNGNGTYSGSLSLGGPGDKLSFLLSGSYRDrdgyldyrnGGFVGNSGYERYNLNAKLGyRLSDNHRLSLS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 235 AMAYHNRWSSTDQIPlravrsGQIGRFDAIDPTDGGDSSRYSLSFNKQHRDqhgGWQMSAYAVRSELDLYSNFTYLKDDP 314
Cdd:COG4771 240 GGYSRQDRDGGPPTL------GDTEISSDNAGDRDTTTDRGNYSLRYNGDL---GDNLDLSLYYSRTDRDSTNGSLGGST 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 315 INGDQFNQSEkrtmLGVNLSKSWLgelagLPMENKL--GVQTRYDKLSPVALYNTAQkqrlslirsdmVEESSAGLYAEN 392
Cdd:COG4771 311 GSFSDSDDTT----YGLELDLTYP-----LGGNHTLtlGAEYRYDDLDSSSFLGGAD-----------ASRDTYGLFAQD 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 393 TVWWHEKLRTVAGLRYDRYQfdvkssingNSGNKGDGITSPKLSVIFGPWANTEFFYNIGKGF-------HSNDARGTTQ 465
Cdd:COG4771 371 EWKLTDKLTLTAGLRYDYYS---------TFGASNYTAFSPRLGLRYDLSDNLTLRASYGRGFrapslaeLYGSGTGTPG 441
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 466 TLLPNGNPASPVTplvgTRGSEVGMRTEWIP-GLQSSLAIWQLDIDSELVFVGDAGETEPSRA------SRRYGVEWNNH 538
Cdd:COG4771 442 RYVLGNPDLKPET----SDNYELGLEYRLGNgGLSLSLTGFYTDIKDLIVLVPVGPGPGDVLQyenvgkARTYGLELELK 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 539 YVVNDWLLLDMDLALSKARFThTDPAGQYIPGAINKVASLGATVTNWGNWFGSVQLRYFGPR---PLVEDNSVRSNSTFL 615
Cdd:COG4771 518 YRLGKGLTLTASYTYLDSKID-DGDTGEPLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRyvtPPSGRLEGYTPGYTL 596
|
650
....*....|....*.
gi 902768162 616 TYARVGYRYNPRTTFT 631
Cdd:COG4771 597 LDLRASYKLTKNLTLS 612
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
216-680 |
8.24e-21 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 95.99 E-value: 8.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 216 YNGVLRYSEGDAHDSMTLTAMAYHNRWSSTDQIPLRAVRSGQIGRFDAI--DPTDGGDSSRYSLSFNKQHRDQHG-GWQM 292
Cdd:pfam00593 2 WQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYygRDYSDTDRKRLSLGYDYDLGDGLSwLSTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 293 SAYAVRSELDLYSNFTYLKDDPiNGDQFNQSEKRTMLGVNLSKSWLGELAGLPM--ENKLGVQTRYDKLSPVALYNTAQK 370
Cdd:pfam00593 82 RLGLRYSSLDGDYTSNSSGLSG-AGDYLSDDRLYGLYGLDGDLELSLDLSHDLLlgVELRTAGLDYRRLDDDAYDPYDPA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 371 QRLSLIRSDmVEESSAGLYAENTVWWHEKLRTVAGLRYDRYQFDVKSS-INGNSGNKGDGITSPKLSVIFGPWANTEFFY 449
Cdd:pfam00593 161 NPSSSSYSD-TTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGnGGGDNFSRSYSAFSPRLGLVYKPTDNLSLYA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 450 NIGKGFH-------SNDARGTTQTLLPNGNPA-SPVTplvgTRGSEVGMRTEWiPGLQSSLAIWQLDIDSELVFVGDAGE 521
Cdd:pfam00593 240 SYSRGFRapslgelYGSGSGGGGGAVAGGNPDlKPET----SDNYELGLKYDD-GRLSLSLALFYIDIKNLITSDPDGPG 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 522 TEPSR-------ASRRYGVEWNNHYvvNDWllldmDLALSKARFTHTD--------PAGQYIPGAINKVASLGAT-VTNW 585
Cdd:pfam00593 315 LGGTVytytnvgKARIRGVELELSG--RLW-----GLGLSGGGYTYTDadddadadDTGNPLPNVPRHTANLGLTyDFPL 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 586 GNWFGSVQLRYFGPRPLV---EDNSVRSNSTFLTYARVGYRYNPRTTFTLDVFNLFDRKASDIDYYYESQLAGeatpvnd 662
Cdd:pfam00593 388 GGWGARLGARYVGSGERRygdAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGGGNLGG------- 460
|
490
....*....|....*...
gi 902768162 663 khfHPVEPRSARLTVTYN 680
Cdd:pfam00593 461 ---YPGPGRTFYLGLSYK 475
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
57-681 |
2.73e-19 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 92.09 E-value: 2.73e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 57 IKNRPISRVGEIMEFVPGMIVTQHSGSGKANQFYLRGFNLdhgtdfATYVDDMPVN-MRTHAHGQgytdlNFLI-PELVS 134
Cdd:TIGR01783 14 LEDQQAGSLSEALQRVPGVVVGGSGGTTQFGNITIRGFGL------EVDIDNVYLDgVPLLSRGN-----LAIVdPAMVE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 135 HIHYKKGPYSAEEGDFSSAGAarlhlLN-------QLPQGIASLTVGSYDYQRMLLANSVAV-ADGHLLYALDVNHYDGP 206
Cdd:TIGR01783 83 RVEVLRGPASLLYGGSAPGGV-----INivtkrpqDEPKGSVTFGAGTRSGYRTAFDLGGPLgADGTFRGRLNGARQDGD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 207 WQVAEGVKKYNGVLRYSEGDAHDSMTLTAMAYHNRWSSTDQ---IPLRAVRSGQIGRFDAI------DPTDGGDSSRYSL 277
Cdd:TIGR01783 158 SFYDGAGEETRLGATATDWQLDDRTLLRLGAYYQKERDRGGyggLPASGGTSGRDLSSDRYlgtssnRNYDDREYLSYGL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 278 SFNKQHRDqhgGWQMSAYAVRSELDLYSNFTYL-------KDDPINGDQFNQSEKRTMLGVNLSkswlGELAGLPMENKL 350
Cdd:TIGR01783 238 SLEYQFND---VWTGKQNLRYSYFDTDSNQVQAsgyssdgGLFGRSLTVVNVKQDRVQIDAGLD----GEFETGPIEHDL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 351 GVQTRYDKLSPVALYNTAQ-------KQRLSLIRSDMVEESSA----------GLYAENTVWWHEKLRTVAGLRYDRYQF 413
Cdd:TIGR01783 311 LLGVSYGQRTTNRFNNTGYpsdniysLTATSSARTDIGDSPKDralssttkalNGVALQRILLADKWTLTLGGRYDSVDV 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 414 DVKSSINGNSGNKGDGITSPKLSVIFGPWANTEFFYNIGKGFHSNDARGTTQTLlpNGNPASPVTplvgTRGSEVGMRTE 493
Cdd:TIGR01783 391 KSNNGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGGYYPKGAGN--SGDILEPEK----GKNYELGVRYD 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 494 WIPGLQSSLAIWQLDIDSELVfVGDAGETEPSRASRR--YGVEWNNHYVVNDWLLLDMDLALSKARFTHT---DPAGQYI 568
Cdd:TIGR01783 465 LGDSLLATAALFRITKDNQLV-QDPVNGTFSVNAGKTrnRGVELEARGYLTPGLSLSAGYTYTDAEFTEDtngDTQGNTV 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 569 PGAINKVASLGAT---VTNWGNWFGSVQLRYFGPRPLVEDNSVRSNSTFLTYARVGYRYNPRTTFTLDVF--NLFDRkas 643
Cdd:TIGR01783 544 PFVPKHTASLWASyapPVGDNGLTLGGGVQYTGKAYVDGGNTGKVPSYTVVDLSVRYDLTKKKNLTLALNvnNLFDR--- 620
|
650 660 670
....*....|....*....|....*....|....*...
gi 902768162 644 diDYYYESQLAGeatpvNDKHFHPVEPRSARLTVTYNF 681
Cdd:TIGR01783 621 --DYYTSGYRWG-----PSAYIYPGAPRTVGLSVSYDF 651
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
46-313 |
3.64e-17 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 82.23 E-value: 3.64e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 46 AASEGKVNASLIKNRPISRVGEIMEFVPGMIVTQHSGSGKANQFYLRGFNLDHgtdFATYVDDMPVNMRThahgQGYTDL 125
Cdd:COG4206 16 TGSVTVIDAEELERSGATSLADALRRVPGVQVSSSGGPGSAASISIRGLGSNQ---TLVLIDGVPLNDPS----LGGVDL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 126 NFLIPELVSHIHYKKGPYSAEEGDFSSAGAARLHLL--NQLPQGIASLTVGSYDYQRmlLANSVAVADGHLLYALDVNHY 203
Cdd:COG4206 89 SLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKkgKKGFKGSVSASYGSFGTRR--LSASLSGGAGKFSYSLSASYR 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 204 DgpwqvAEGVKKYNGVLRYSegDAHDSMTLTAMAYHnRWSSTDQIPLRAVRSGQIGRFDAIDPTDggDSSRYSLSFNKQH 283
Cdd:COG4206 167 R-----SDGYRYNDPDLRNN--DGYENTSLNARLGY-KLGDNGSLSLSGGYSDSERGYPGAVGSD--RNLRLSLSLEYKL 236
|
250 260 270
....*....|....*....|....*....|
gi 902768162 284 RDQHGGWQMSAYAVRSELDLYSNFTYLKDD 313
Cdd:COG4206 237 SDGWSLLLLAYYYYDRDYEDGGGDSAGTSN 266
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
52-155 |
2.55e-13 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 66.52 E-value: 2.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 52 VNASLIKNRPISRVGEIMEFVPGmIVTQHSGSGKANQFYLRGFNldhGTDFATYVDDMPVNMrthaHGQGYTDLNFLIPE 131
Cdd:pfam07715 12 VTAEDIEDQGATNLADALRGVPG-VSVSSGGGGGGSSISIRGFG---SNRVLVLVDGVPLNS----GGGGSVDLNSIDPE 83
|
90 100
....*....|....*....|....
gi 902768162 132 LVSHIHYKKGPYSAEEGDFSSAGA 155
Cdd:pfam07715 84 DIERVEVLKGPASALYGSGAIGGV 107
|
|
| TonB-hemin |
TIGR01785 |
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ... |
28-681 |
4.95e-12 |
|
TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273807 [Multi-domain] Cd Length: 665 Bit Score: 68.96 E-value: 4.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 28 LDEVEVRGHYDNAVGSSDAASEGKVNASLIKNRPISRVGEIMEFVPGMIVTQhSGSGKANQFYLRGFNldhGTDFATYVD 107
Cdd:TIGR01785 1 LDTVTVTATRTRQVLSEAPASVSVISGEQIESKQANNLADALNTVPGVDVTG-GGRPPGQSINIRGLQ---DNRVLVVVD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 108 DMPVNMRTHAHGQGytdLNFLIPELVSHIHYKKGPYSAEEGDFSSAGAARLHLL--------NQLPQGIASLTVGSYDYQ 179
Cdd:TIGR01785 77 GARQNYQRGGAHNG---SLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKdaadllrpGQLFGGLAKLSYGSNNNS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 180 RMLlanSVAVAdGHLLYALDVNHYDGPWQVAE------------GVKKYNGV--LRYSEGDAHDsmtLTAMAYHNRWSST 245
Cdd:TIGR01785 154 FGG---SVAVA-GRLDDNLDALVAATYRDGGNyrngnkeeatnsAYVQKNLLakLGWQLDDAQR---LEFSYFTTEGSLD 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 246 DQiplRAVRSGQIGRFDAIDPTDGGDSSRYSLSFNKQHRDQHGGWqmsayaVRSELDLYSNFTYLKDDPiNGDQFNQSEK 325
Cdd:TIGR01785 227 EA---QNSGPGTEYVLGSSSTLLASSTRDRSATLTYNWTPEDNPW------LDATASLYYNRTENDNDR-SARGVGREEG 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 326 R--TMLGVNLSKSWLGELAGLPMENkLGVQTRYDKL---------SPVALYNTAQkqrlslirsdmVEESSAGLYAE-NT 393
Cdd:TIGR01785 297 YqyTTYGATLQNTSRFDVASWSTLT-YGVDWMKDKRrtesfdpnsVTTIVPNPPS-----------AKEYFFGLFLQdNI 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 394 VWWHEKLRTVAGLRYDRYQFDVKSSINGNSGNKGDGITSPK--LSVIFGPWANteFFYNIGKGF-----------HSNDA 460
Cdd:TIGR01785 365 PLLDDRLTLSAGLRYDHYKLSPKTTADTEAVDRSYSRWSPSlgLSYKPVDWLT--LYASYSQGFrapsidelygtGDHPG 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 461 RGTTQTLLPNGN--PASPVTPLVGTRGSEVGMRTEWIPgLQSSLAIWQLDIDS--ELVFVGDAGETEPSRA--------- 527
Cdd:TIGR01785 443 TPGGYTFAPNPNlkPETSKTWELGANLSFDNLLLDNDQ-LQFKVAYFYNDVKDfiDLTIGVTDNVTAGMNNitqyvnidg 521
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 528 SRRYGVEWNNHYvvnDWLLLDMDLALSKARFTHTdPAGQYipgaINKVASLGATVT------NWGnWFGSVQLRYFGPR- 600
Cdd:TIGR01785 522 ARIRGIEASASY---DAGLWATGLSYGYTIGKDQ-NTNQW----LSNIPPLKLVVTvgyrfpDRR-LDLGAKAAYYERQs 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 902768162 601 PLVEDNSVRSNSTFLT--YARVGYR--YNPRT----TFTLDVFNLFDRKasdidyYYESQLAGEATPvndkhfhpvePRS 672
Cdd:TIGR01785 593 ESPTTEDVAANGLLTTpgYTVVDLYatYQPNAvkglTVRFGVNNLTDRK------YTPAQSVPGAGP----------GRN 656
|
....*....
gi 902768162 673 ARLTVTYNF 681
Cdd:TIGR01785 657 FKGSVKYQF 665
|
|
| |
