|
Name |
Accession |
Description |
Interval |
E-value |
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
3-722 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 734.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 3 IAGLLLVIIIGAGSLFGI--SLFKGLPSLEELENPKPNLASLVYSEDGVLLHKFFLENRTFVPLKSISKWVPKALIATED 80
Cdd:COG5009 8 LILLLLLLLLGALAVAGLylYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLINAFLAAED 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 81 VAFYQHWGVDLRRLTLAMGENIIKGRTRwHGASTITQQLAKNLFLTQERTLSRKAKELITAIELEKTYTKDEILALYLNT 160
Cdd:COG5009 88 KRFYEHPGVDPIGIARAAVVNLRTGRRV-QGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEILELYLNK 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 161 VYFGSGAYGIEAAANTYFGKKASELTIPESASLIATLKNPTAYNPAKNPSTALGRRNLIIGLMEKEGFITHAQAVKAKAT 240
Cdd:COG5009 167 IYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEYEAAKAE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 241 PVTLHYTPSTHHGLAPYFTEYIRQNIktSSQLDGVNVYSDGLTIQTTLDSRMQRYaqeaIAQQAAALQAEFDKR------ 314
Cdd:COG5009 247 PLTARYHGASAEVDAPYFAEMVRREL--VERYGEDALYTGGLKVYTTLDPRLQEA----AEKALRDGLLAYDRRhgyrgp 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 315 ----WTCSDALKKqFIKESPQY------------------------------------RELVNEEGVAPA-TALSKLLA- 352
Cdd:COG5009 321 eahlDLAEEDWDE-ALAEVPDVgdlrpavvlevddksarvglrdgetgtlpleglkwaRPYINDNRRGPApKSASDVLKp 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 353 -DKVFVKNLLHDKSR------VQMALISLDPTNGHVKAWVGGTNFspddYRYQFDHVWQAKRQPGSTFKPFVYSAAIDQG 425
Cdd:COG5009 400 gDVIRVRPVADGGWRlrqipeVQGALVALDPHTGAVLALVGGFDF----EQSKFNRATQAKRQPGSSFKPFVYAAALDNG 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 426 IPANYRILDQPLALR-GGDGSVWMARNSEGQSGGMTTLRDALRRSLNQVTIRLAyQFLTPSEIISYARRMGITTPMQPNL 504
Cdd:COG5009 476 YTPATIINDAPIVFDdGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLL-QDVGIDYVIDYAERFGIYSKLPPNL 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 505 SIALGTSEVSPLVLAQAFTTFANNGTWSEPLPVTKVLDKRGGLITEHKPVSHFG---------------------LDPAS 563
Cdd:COG5009 555 SLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARACEdcdaaewdgaeprlpdpaeqvIDPRT 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 564 NFVMVTMLKDVIDRGTGIAVRArygFDAEAGGKTGTTQSMRDAWFAGFTPQLVTVVWAGFDDERvhftSM-SYGQGARAA 642
Cdd:COG5009 635 AYQMTSMLRGVVQRGTGRRARA---LGRDIAGKTGTTNDSKDAWFVGFTPDLVAGVWVGFDDPR----SLgRGETGGRAA 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 643 LPAWASFMKKCYDDpelhLENRYFTMPDNVIAVPISAGSGDQGDLFNRDVYVEYFTPkGFARYRSGELNNTPPPAQQESD 722
Cdd:COG5009 708 LPIWIDFMKAALKD----KPEKPFPVPEGIVTVRIDPKTGLLASPGDPDAIFEAFKP-GTEPTESASEDLGPDASEGTGE 782
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
58-651 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 566.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 58 NRTFVPLKSISKWVPKALIATEDVAFYQHWGVDLRRLTLAMGENIIKGRTRwHGASTITQQLAKNLFLTQERTLSRKAKE 137
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVL-EGGSTITQQLAKNLYLTNERTITRKIQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 138 LITAIELEKTYTKDEILALYLNTVYFGSGAYGIEAAANTYFGKKASELTIPESASLIATLKNPTAYNPAKNPSTALGRRN 217
Cdd:TIGR02074 80 ALLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 218 LIIGLMEKEGFITHAQAVKAKATPVTLH-YTPSTHHGLAPYFTEYIRQNIKTssqLDGVNVYSDGLTIQTTLDSRMQRYA 296
Cdd:TIGR02074 160 LVLSNMVENGYITAEEAEEAINEPIQLYlQTKKSEQYKAPYFVDYVIQELEE---EYGEELYTGGLKIYTTLDLDAQKAA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 297 QeaiaqqaaalqaefdkrwtcsdalkkqfikespqyrELVNEEGVAPATAlsklladkvfvknllhDKSRVQMALISLDP 376
Cdd:TIGR02074 237 E------------------------------------KVLNTGLRVAGRR----------------DGDDLQAALVAIDP 264
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 377 TNGHVKAWVGGTNFSPDdyryQFDHVWQAKRQPGSTFKPFVYSAAIDQGIPANYRILDQPLALRGGDGsvWMARNSEGQS 456
Cdd:TIGR02074 265 DTGAVRALVGGRDYGKS----QFNRATQAKRQPGSTFKPFVYAAALEKGLTPATIVNDEPITYNGNGP--WSPKNYGGGY 338
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 457 GGMTTLRDALRRSLNQVTIRLAyQFLTPSEIISYARRMGITTPMQPNLSIALGTSEVSPLVLAQAFTTFANNGTWSEPLP 536
Cdd:TIGR02074 339 RGNVTLRQALAQSRNIPAVRLL-QEVGLDKVVALAKRFGITSPLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHG 417
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 537 VTKVLDKRGGLITEHKPVSHFGLDPASNFVMVTMLKDVIDRGTGiavRARYGFDAEAGGKTGTTQSMRDAWFAGFTPQLV 616
Cdd:TIGR02074 418 IRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTG---RSARLPGRPVAGKTGTTQNWRDAWFVGYTPYYV 494
|
570 580 590
....*....|....*....|....*....|....*
gi 908399932 617 TVVWAGFDDERvhfTSMSYGQGARAALPAWASFMK 651
Cdd:TIGR02074 495 TAVWVGYDDKK---TLGKSGTGGGLAAPIWRDFMA 526
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-682 |
1.09e-102 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 334.79 E-value: 1.09e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 1 MKIAGLLLV-----IIIGAGSLFGisLFK----GLPSLEELENPKPNLASLVYSEDGVLLHKFFLENRTFVPLKSISKWV 71
Cdd:PRK11636 1 MKFVKYLLIlavccILLGAGSIYG--LYRyiepQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 72 PKALIATEDVAFYQHWGVD----LRRLTLAMgeniIKGRTRwHGASTITQQLAKNLFLTQERTLSRKAKELITAIELEKT 147
Cdd:PRK11636 79 VKAFIATEDSRFYEHHGVDpvgiFRAASVAL----FSGHAS-QGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 148 YTKDEILALYLNTVYFGSGAYGIEAAANTYFGKKASELTIPESAsLIATL-KNPTAYNPAKNPSTALGRRNLIIGLMEKE 226
Cdd:PRK11636 154 LTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMA-VIAGLpKAPSTFNPLYSMDRAVARRNVVLSRMLDE 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 227 GFITHAQAVKAKATPVTLHYTPSTHHGLAPYFTEYIRQNIktsSQLDGVNVYSDGLTIQTTLDSRMQryaqEAIAQQAAA 306
Cdd:PRK11636 233 GYITQAQYDQARSEPIVANYHAPEIAFSAPYLSEMVRQEM---YNRYGENAYEDGYRVYTTITRKVQ----QAAQQAVRN 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 307 LQAEFDKR-----------------WTCSDALKKqfIKESPQYREL----VNEEGVAPATAlskLLAD------------ 353
Cdd:PRK11636 306 NVLDYDMRhgyrgpanvlwkvgesaWDNKKITDT--LKALPTYGPLlpavVTSANPQEATA---MLADgssvalpmegvr 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 354 --------------------------KVFVKNL-----LHDKSRVQMALISLDPTNGHVKAWVGGTNFSpddyRYQFDHV 402
Cdd:PRK11636 381 warpyrsdtqqgptprkvtdvvqtgqQIWVRQVddawwLAQVPDVNSALVSINPQNGAVMALVGGFDFN----QSKFNRA 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 403 WQAKRQPGSTFKPFVYSAAIDQGIPANYRILDQPLA-LRGGDGSVWMARNSEGQSGGMTTLRDALRRSLNQVTIRlAYQF 481
Cdd:PRK11636 457 TQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISrWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVR-AMRA 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 482 LTPSEIISYARRMGIttPMQpNL----SIALGTSEVSPLVLAQAFTTFANNGTWSEPLPVTKVLDKRGGLITEHKP---- 553
Cdd:PRK11636 536 MGVDYAAEYLQRFGF--PAQ-NIvhteSLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPkvac 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 554 ---------------------------VSHFG---------LDPAS-----------------NFVMVTMLKDVIDR--- 577
Cdd:PRK11636 613 pecdipviygdtqksnvlenddvenvaTSQEQqnssvpmpqLEQANqalvaqngaqeyaphviNTPLAFLIKSALNTnif 692
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 578 ------GTGiavrARYGFD---AEAGGKTGTTQSMRDAWFAGFTPQLVTVVWAGFDDERVHF--TSMS---------YGQ 637
Cdd:PRK11636 693 gepgwmGTG----WRAGRDlkrRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRDLgrTTASgaikdqisgYEG 768
|
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 908399932 638 GARAALPAWASFMKKCYDD-PELHLenryfTMPDNVIAVPISAGSG 682
Cdd:PRK11636 769 GAKSAQPAWDDYMKAALEGvPEQPL-----TPPPGIVTVNIDRSTG 809
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
47-224 |
7.40e-85 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 265.92 E-value: 7.40e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 47 DGVLLHKFFLENRTFVPLKSISKWVPKALIATEDVAFYQHWGVDLRRLTLAMGENIIKGRTRwHGASTITQQLAKNLFLT 126
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIV-QGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 127 QERTLSRKAKELITAIELEKTYTKDEILALYLNTVYFGSGAYGIEAAANTYFGKKASELTIPESASLIATLKNPTAYNPA 206
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 908399932 207 KNPSTALGRRNLIIGLME 224
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
3-722 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 734.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 3 IAGLLLVIIIGAGSLFGI--SLFKGLPSLEELENPKPNLASLVYSEDGVLLHKFFLENRTFVPLKSISKWVPKALIATED 80
Cdd:COG5009 8 LILLLLLLLLGALAVAGLylYLSPDLPDVETLKDYQPPTPSRVYSADGKLIAEFGEERRIPVPIEEIPPLLINAFLAAED 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 81 VAFYQHWGVDLRRLTLAMGENIIKGRTRwHGASTITQQLAKNLFLTQERTLSRKAKELITAIELEKTYTKDEILALYLNT 160
Cdd:COG5009 88 KRFYEHPGVDPIGIARAAVVNLRTGRRV-QGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEILELYLNK 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 161 VYFGSGAYGIEAAANTYFGKKASELTIPESASLIATLKNPTAYNPAKNPSTALGRRNLIIGLMEKEGFITHAQAVKAKAT 240
Cdd:COG5009 167 IYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEYEAAKAE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 241 PVTLHYTPSTHHGLAPYFTEYIRQNIktSSQLDGVNVYSDGLTIQTTLDSRMQRYaqeaIAQQAAALQAEFDKR------ 314
Cdd:COG5009 247 PLTARYHGASAEVDAPYFAEMVRREL--VERYGEDALYTGGLKVYTTLDPRLQEA----AEKALRDGLLAYDRRhgyrgp 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 315 ----WTCSDALKKqFIKESPQY------------------------------------RELVNEEGVAPA-TALSKLLA- 352
Cdd:COG5009 321 eahlDLAEEDWDE-ALAEVPDVgdlrpavvlevddksarvglrdgetgtlpleglkwaRPYINDNRRGPApKSASDVLKp 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 353 -DKVFVKNLLHDKSR------VQMALISLDPTNGHVKAWVGGTNFspddYRYQFDHVWQAKRQPGSTFKPFVYSAAIDQG 425
Cdd:COG5009 400 gDVIRVRPVADGGWRlrqipeVQGALVALDPHTGAVLALVGGFDF----EQSKFNRATQAKRQPGSSFKPFVYAAALDNG 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 426 IPANYRILDQPLALR-GGDGSVWMARNSEGQSGGMTTLRDALRRSLNQVTIRLAyQFLTPSEIISYARRMGITTPMQPNL 504
Cdd:COG5009 476 YTPATIINDAPIVFDdGGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVRLL-QDVGIDYVIDYAERFGIYSKLPPNL 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 505 SIALGTSEVSPLVLAQAFTTFANNGTWSEPLPVTKVLDKRGGLITEHKPVSHFG---------------------LDPAS 563
Cdd:COG5009 555 SLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARACEdcdaaewdgaeprlpdpaeqvIDPRT 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 564 NFVMVTMLKDVIDRGTGIAVRArygFDAEAGGKTGTTQSMRDAWFAGFTPQLVTVVWAGFDDERvhftSM-SYGQGARAA 642
Cdd:COG5009 635 AYQMTSMLRGVVQRGTGRRARA---LGRDIAGKTGTTNDSKDAWFVGFTPDLVAGVWVGFDDPR----SLgRGETGGRAA 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 643 LPAWASFMKKCYDDpelhLENRYFTMPDNVIAVPISAGSGDQGDLFNRDVYVEYFTPkGFARYRSGELNNTPPPAQQESD 722
Cdd:COG5009 708 LPIWIDFMKAALKD----KPEKPFPVPEGIVTVRIDPKTGLLASPGDPDAIFEAFKP-GTEPTESASEDLGPDASEGTGE 782
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
3-675 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 684.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 3 IAGLLLVIIIGAGSLFGISLFKGLPSLEELENPKPNLASLVYSEDGVLLHKFFLENRTFVPLKSISKWVPKALIATEDVA 82
Cdd:COG0744 18 LLLLLAVLVLAALAGLVALYVADLPDPEELEDLALPQTSTIYDRDGTLIATLGDENREWVPLDQIPPHLKDAVVAIEDRR 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 83 FYQHWGVDLRRLTLAMGENIIKGRTRwHGASTITQQLAKNLFLTQERTLSRKAKELITAIELEKTYTKDEILALYLNTVY 162
Cdd:COG0744 98 FYEHGGVDPKGIARALVANLTAGGVV-QGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVY 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 163 FGSGAYGIEAAANTYFGKKASELTIPESASLIATLKNPTAYNPAKNPSTALGRRNLIIGLMEKEGFITHAQAVKAKATPV 242
Cdd:COG0744 177 FGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPL 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 243 TLHYTP-STHHGLAPYFTEYIRQNIKtsSQLDGVNVYSDGLTIQTTLDSRMQRYaqeaiaqqaaalqaefdkrwtcsdal 321
Cdd:COG0744 257 TLVPPPnGAAAGKYPYFVDYVRRELE--ELLGEDDLYRGGLKIYTTLDPKLQKA-------------------------- 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 322 kkqfikespqyrelvneegvapatalskllADKVFVKNLLHDKSR-VQMALISLDPTNGHVKAWVGGTNFSpddyRYQFD 400
Cdd:COG0744 309 ------------------------------AEKAVKNVLPEGKPGgLQAALVVVDPKTGEVLAMVGGRDYG----KSQFN 354
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 401 HVWQAKRQPGSTFKPFVYSAAIDQGIPANYRILDQPLALRGGDgsvWMARNSEGQSGGMTTLRDALRRSLNQVTIRLAyQ 480
Cdd:COG0744 355 RATQAKRQPGSTFKPFVYAAALEQGYTPATTVDDEPVTFPGGG---WSPKNYDGRYRGPVTLREALANSLNTPAVRLA-Q 430
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 481 FLTPSEIISYARRMGITTPMQPNLSIALGTSEVSPLVLAQAFTTFANNGTWSEPLPVTKVLDKRGGLITEHKPVSHFGLD 560
Cdd:COG0744 431 EVGLDKVVDTARRLGITSPLDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVIS 510
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 561 PASNFVMVTMLKDVIDRGTGiavRARYGFDAEAGGKTGTTQSMRDAWFAGFTPQLVTVVWAGFDDErvhfTSMSYGQGAR 640
Cdd:COG0744 511 PEVAYLMTDMLQDVVTSGTG---RAARLPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDN----SPMGYVTGGS 583
|
650 660 670
....*....|....*....|....*....|....*
gi 908399932 641 AALPAWASFMKKCYDDpelhLENRYFTMPDNVIAV 675
Cdd:COG0744 584 LPAPIWRDFMEAALEG----LPVEDFPKPSGVVRI 614
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
58-651 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 566.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 58 NRTFVPLKSISKWVPKALIATEDVAFYQHWGVDLRRLTLAMGENIIKGRTRwHGASTITQQLAKNLFLTQERTLSRKAKE 137
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVL-EGGSTITQQLAKNLYLTNERTITRKIQE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 138 LITAIELEKTYTKDEILALYLNTVYFGSGAYGIEAAANTYFGKKASELTIPESASLIATLKNPTAYNPAKNPSTALGRRN 217
Cdd:TIGR02074 80 ALLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 218 LIIGLMEKEGFITHAQAVKAKATPVTLH-YTPSTHHGLAPYFTEYIRQNIKTssqLDGVNVYSDGLTIQTTLDSRMQRYA 296
Cdd:TIGR02074 160 LVLSNMVENGYITAEEAEEAINEPIQLYlQTKKSEQYKAPYFVDYVIQELEE---EYGEELYTGGLKIYTTLDLDAQKAA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 297 QeaiaqqaaalqaefdkrwtcsdalkkqfikespqyrELVNEEGVAPATAlsklladkvfvknllhDKSRVQMALISLDP 376
Cdd:TIGR02074 237 E------------------------------------KVLNTGLRVAGRR----------------DGDDLQAALVAIDP 264
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 377 TNGHVKAWVGGTNFSPDdyryQFDHVWQAKRQPGSTFKPFVYSAAIDQGIPANYRILDQPLALRGGDGsvWMARNSEGQS 456
Cdd:TIGR02074 265 DTGAVRALVGGRDYGKS----QFNRATQAKRQPGSTFKPFVYAAALEKGLTPATIVNDEPITYNGNGP--WSPKNYGGGY 338
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 457 GGMTTLRDALRRSLNQVTIRLAyQFLTPSEIISYARRMGITTPMQPNLSIALGTSEVSPLVLAQAFTTFANNGTWSEPLP 536
Cdd:TIGR02074 339 RGNVTLRQALAQSRNIPAVRLL-QEVGLDKVVALAKRFGITSPLDPVLSLALGTVEVSPLEMASAYAVFANGGKYVEPHG 417
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 537 VTKVLDKRGGLITEHKPVSHFGLDPASNFVMVTMLKDVIDRGTGiavRARYGFDAEAGGKTGTTQSMRDAWFAGFTPQLV 616
Cdd:TIGR02074 418 IRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTG---RSARLPGRPVAGKTGTTQNWRDAWFVGYTPYYV 494
|
570 580 590
....*....|....*....|....*....|....*
gi 908399932 617 TVVWAGFDDERvhfTSMSYGQGARAALPAWASFMK 651
Cdd:TIGR02074 495 TAVWVGYDDKK---TLGKSGTGGGLAAPIWRDFMA 526
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
25-672 |
7.03e-105 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 337.46 E-value: 7.03e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 25 GLPSLEELENPK--------PNLASLVYSEDGvllhkfflENRTFVPLKSISKWVPKALIATEDVAFYQHWGVDLRRLTL 96
Cdd:TIGR02071 113 QLSKIENLDNNKefgffrldPKLIAMLYSPNG--------EQRLFVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGR 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 97 AMGENIIKGRTRwHGASTITQQLAKNLFLTQERTLSRKAKELITAIELEKTYTKDEILALYLNTVYFG-SGA---YGIEA 172
Cdd:TIGR02071 185 AVWVNLTAGRTV-QGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILDARYSKDRILELYLNEVYLGqSGDdaiHGFPL 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 173 AANTYFGKKASELTIPESASLIATLKNPTAYNPAKNPSTALGRRNLIIGLMEKEGFITHAQAVKAKATPVTLHYTPS--T 250
Cdd:TIGR02071 264 ASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQKIIDDEEYDMLSARPLGVQKKGGiiS 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 251 HHglaPYFTEYIRQNIKtssQLDGVNVYSD-GLTIQTTLDSRMQRYAqeaiaqqaaalqaefdkrwtcsdalkkqfikes 329
Cdd:TIGR02071 344 RQ---PAFLQLVRRELR---QKLGDKVKDLsGLRIFTTLDPVSQSAA--------------------------------- 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 330 pqyrELVNEEGVaPATALSKLLADkvfvknllhdksrVQMALISLDPTNGHVKAWVGGTnfspdDYRYQ-FDHVWQAKRQ 408
Cdd:TIGR02071 385 ----EQAVQETI-PALKKKKKLPD-------------LEAAMVVTDRFTGEVRAMVGGS-----DPQFAgFNRALQARRQ 441
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 409 PGSTFKPFVYSAAIDQgiPANYR----ILDQPLALRGGDGSVWMARNSEGQSGGMTTLRDALRRSLNQVTIRLAYQfLTP 484
Cdd:TIGR02071 442 IGSLVKPAVYLTALSQ--PDKYRlntwIEDQPLSIKLSNGQVWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMK-VGL 518
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 485 SEIISYARRMGIT-TPMQPNLSIALGTSEVSPLVLAQAFTTFANNGTWSEPLPVTKVLDKRGGLITEHKP-VSHFGLDPA 562
Cdd:TIGR02071 519 PKVSQTWNKLGINkDEIPPVPSMLLGAINLTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDGKVLYQSDPqAEQAVPSQA 598
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 563 SNFVMVTMlKDVIDRGTGIAVRARYGfDAEAGGKTGTTQSMRDAWFAGFTPQLVTVVWAGFDDErvHFTSMSygqGARAA 642
Cdd:TIGR02071 599 AYLTLYAM-QQVVQRGTARSLGADFP-SLSLAGKTGTTNDNRDSWFAGIDGKEVTIIWLGRDDN--GPTKLT---GASGA 671
|
650 660 670
....*....|....*....|....*....|
gi 908399932 643 LPAWASFMKKcyddpeLHLENRYFTMPDNV 672
Cdd:TIGR02071 672 LQVYARYLSY------QTPEPLLLVPPEGI 695
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
2-701 |
7.20e-103 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 332.95 E-value: 7.20e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 2 KIAGLLLVIIIGAGSLFGISLFKGLPSLEELEnpkpnLASLVYSEDGVLLHKFFLEN---RTFVPLKSISKWVPKALIAT 78
Cdd:COG4953 10 RLLALLLALLLLALALWALDRLFPLPLLFAVP-----YSTVVLDRDGTLLRAFLAADgqwRLPVPLDEVSPRYLQALLAY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 79 EDVAFYQHWGVDLRRLTLAMGENIIKGRtRWHGASTITQQLAKnLFLTQERTLSRKAKELITAIELEKTYTKDEILALYL 158
Cdd:COG4953 85 EDRRFYYHPGVNPLALLRAAWQNLRSGR-IVSGGSTLTMQVAR-LLEPRPRTLSGKLRQILRALQLERRYSKDEILELYL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 159 NTVYFGSGAYGIEAAANTYFGKKASELTIPESASLIATLKNPTAYNPAKNPSTALGRRNLIIGLMEKEGFITHAQAVKAK 238
Cdd:COG4953 163 NLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGVIDAEEAALAL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 239 ATPVTLHYTPSTHhgLAPYFTEYIRQNiktssqldgvnvYSDGLTIQTTLDSRMQRyaqeaiaqqaaalqaefdkrwtcs 318
Cdd:COG4953 243 LEPVPARRRPLPQ--LAPHLARRLLRQ------------LPGGTRIRTTLDAGLQR------------------------ 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 319 dalkkqfikespqyrelvneegvapatALSKLLADKVfvkNLLHDKSRVQMALISLDPTNGHVKAWVGGTNFSpDDYRY- 397
Cdd:COG4953 285 ---------------------------RLERLVRRYV---RRLKQNGIHNAAVLVVDNRTGEVLAYVGSADFF-DASRQg 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 398 QFDHVwQAKRQPGSTFKPFVYSAAIDQG-IPANYRILDQPLALRGgdgsvWMARNSEGQSGGMTTLRDALRRSLNQVTIR 476
Cdd:COG4953 334 QVDMV-RALRSPGSTLKPFLYGLALDQGlIHPETLLADVPTSFGG-----YRPENFDGTFQGPVSAREALARSLNIPAVR 407
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 477 LAYQfLTPSEIISYARRMGITTPMQ----PNLSIALGTSEVSPLVLAQAFTTFANNGTWSEPlpvtkVLDKRGGLITEhK 552
Cdd:COG4953 408 LLEA-LGPARFYARLRRAGLRLLLPpaehYGLSLILGGAEVTLEELVGLYAALARGGEARPL-----RLLAGEPASPG-R 480
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 553 PVshfgLDPASNFVMVTMLKDVIDRGTGIAVRARYGfdaeAGG---KTGTTQSMRDAWFAGFTPQLVTVVWAG-FDDE-R 627
Cdd:COG4953 481 RL----LSPGAAWLVRDILSDVPRPDGAFGWRALDS----PPPiawKTGTSYGFRDAWAVGFTGRYTVGVWVGnPDGTpV 552
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 908399932 628 VHFTsmsygqGARAALPAWASFMKkcyddpelHLENRY----FTMPDNVIAVPISAGSGDQGDLFNRDVYVEYFTPKG 701
Cdd:COG4953 553 PGLT------GAEAAAPLLFDIFD--------LLPASRwplpFPPPAGLLRVEVCAPSGLLAGPNCPQRVTEWFIPGT 616
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
1-682 |
1.09e-102 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 334.79 E-value: 1.09e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 1 MKIAGLLLV-----IIIGAGSLFGisLFK----GLPSLEELENPKPNLASLVYSEDGVLLHKFFLENRTFVPLKSISKWV 71
Cdd:PRK11636 1 MKFVKYLLIlavccILLGAGSIYG--LYRyiepQLPDVATLKDVRLQTPMQVYSADGELIAQYGEKRRIPLTLDQIPPEM 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 72 PKALIATEDVAFYQHWGVD----LRRLTLAMgeniIKGRTRwHGASTITQQLAKNLFLTQERTLSRKAKELITAIELEKT 147
Cdd:PRK11636 79 VKAFIATEDSRFYEHHGVDpvgiFRAASVAL----FSGHAS-QGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 148 YTKDEILALYLNTVYFGSGAYGIEAAANTYFGKKASELTIPESAsLIATL-KNPTAYNPAKNPSTALGRRNLIIGLMEKE 226
Cdd:PRK11636 154 LTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMA-VIAGLpKAPSTFNPLYSMDRAVARRNVVLSRMLDE 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 227 GFITHAQAVKAKATPVTLHYTPSTHHGLAPYFTEYIRQNIktsSQLDGVNVYSDGLTIQTTLDSRMQryaqEAIAQQAAA 306
Cdd:PRK11636 233 GYITQAQYDQARSEPIVANYHAPEIAFSAPYLSEMVRQEM---YNRYGENAYEDGYRVYTTITRKVQ----QAAQQAVRN 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 307 LQAEFDKR-----------------WTCSDALKKqfIKESPQYREL----VNEEGVAPATAlskLLAD------------ 353
Cdd:PRK11636 306 NVLDYDMRhgyrgpanvlwkvgesaWDNKKITDT--LKALPTYGPLlpavVTSANPQEATA---MLADgssvalpmegvr 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 354 --------------------------KVFVKNL-----LHDKSRVQMALISLDPTNGHVKAWVGGTNFSpddyRYQFDHV 402
Cdd:PRK11636 381 warpyrsdtqqgptprkvtdvvqtgqQIWVRQVddawwLAQVPDVNSALVSINPQNGAVMALVGGFDFN----QSKFNRA 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 403 WQAKRQPGSTFKPFVYSAAIDQGIPANYRILDQPLA-LRGGDGSVWMARNSEGQSGGMTTLRDALRRSLNQVTIRlAYQF 481
Cdd:PRK11636 457 TQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISrWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVR-AMRA 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 482 LTPSEIISYARRMGIttPMQpNL----SIALGTSEVSPLVLAQAFTTFANNGTWSEPLPVTKVLDKRGGLITEHKP---- 553
Cdd:PRK11636 536 MGVDYAAEYLQRFGF--PAQ-NIvhteSLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIFEAKPkvac 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 554 ---------------------------VSHFG---------LDPAS-----------------NFVMVTMLKDVIDR--- 577
Cdd:PRK11636 613 pecdipviygdtqksnvlenddvenvaTSQEQqnssvpmpqLEQANqalvaqngaqeyaphviNTPLAFLIKSALNTnif 692
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 578 ------GTGiavrARYGFD---AEAGGKTGTTQSMRDAWFAGFTPQLVTVVWAGFDDERVHF--TSMS---------YGQ 637
Cdd:PRK11636 693 gepgwmGTG----WRAGRDlkrRDIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRDLgrTTASgaikdqisgYEG 768
|
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 908399932 638 GARAALPAWASFMKKCYDD-PELHLenryfTMPDNVIAVPISAGSG 682
Cdd:PRK11636 769 GAKSAQPAWDDYMKAALEGvPEQPL-----TPPPGIVTVNIDRSTG 809
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
38-744 |
3.08e-93 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 306.27 E-value: 3.08e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 38 NLASLVYSEDGVLLHKFFLEN---RTFVPLKSISKWVPKALIATEDVAFYQHWGVDLRRLTLAMGENIIKGRTRwHGAST 114
Cdd:TIGR02073 9 PSSTVVLDRHGTLLRALLANDgqwRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRRV-SGGST 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 115 ITQQLAKNLFLTQERTLSRKAKELITAIELEKTYTKDEILALYLNTVYFGSGAYGIEAAANTYFGKKASELTIPESASLI 194
Cdd:TIGR02073 88 LTMQLARLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLAEAALLA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 195 ATLKNPTAYNPAKNPSTALGRRNLIIGLMEKEGFITHAQAVKAKATPVTLhyTPSTHHGLAPYFT-EYIRQNIKTSSqld 273
Cdd:TIGR02073 168 ALPQAPSARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPLPA--LPEPLPQLAPHFAlKLLRARPEIAS--- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 274 gvnvysdglTIQTTLDSRMQRyaqeaiaqqaaaLQAEFDKRWtcSDALKKQFIKEspqyrelvneegvapatalskllad 353
Cdd:TIGR02073 243 ---------VIVSTLDADLQR------------RLEELARRY--LSALRPRGISN------------------------- 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 354 kvfvknllhdksrvqMALISLDPTNGHVKAWVGGTNFSPDDYRYQFDHVwQAKRQPGSTFKPFVYSAAIDQGIPANYRIL 433
Cdd:TIGR02073 275 ---------------LAILVVDNRSGAVLAYVGSADFFDDSNSGQVDGV-RAPRSPGSTLKPFLYALALDDGLLHPDSLL 338
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 434 -DQPLALRGgdgsvWMARNSEGQSGGMTTLRDALRRSLNQVTIRLAyQFLTPSEIISYARRMGITTPMQ----PNLSIAL 508
Cdd:TIGR02073 339 kDVPLRFGD-----YAPENFDKTFHGPVPAREALARSLNIPAVRLL-ERVGPPRFADFLRQAGLNLLKPksdyYGLSLAL 412
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 509 GTSEVSPLVLAQAFTTFANNGTWSePLPVTKVLDKRggliTEHKPVshfgLDPASNFVMVTMLKDVIDRGTGIAVRARYG 588
Cdd:TIGR02073 413 GGAEITLQDLANLYAMLANQGLSG-PLRFLQTDAKR----PERERL----LSPGAAWIVLDILKDRPRPDDTLPLSALPT 483
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 589 FDAEAgGKTGTTQSMRDAWFAGFTPQLVTVVWAG-FDDE-RVHFTsmsygqGARAALPAWasfmkkcYDDPELHLENRYF 666
Cdd:TIGR02073 484 RLPLA-WKTGTSYGFRDAWAAGVSGRYTIGVWVGnFDGKpNPGFF------GAAAAAPLL-------FDILDALQASEAS 549
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 667 TMPDNVIAVPISAGSGDQGDLFNRDVYVEYFTPKGFAR-----YRSGELNNTPPPAQQESDNPQDSTKTQ---------T 732
Cdd:TIGR02073 550 TLPRPLKEVPGCLVLGNLPILPCPEQISTWFLPGGSPPtlsepHKPVVILINEGIAACLPDKPEARQKLAlfdvaayfaQ 629
|
730
....*....|..
gi 908399932 733 APTPIQMPVLTP 744
Cdd:TIGR02073 630 AGLPKRKPLLER 641
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
47-224 |
7.40e-85 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 265.92 E-value: 7.40e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 47 DGVLLHKFFLENRTFVPLKSISKWVPKALIATEDVAFYQHWGVDLRRLTLAMGENIIKGRTRwHGASTITQQLAKNLFLT 126
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIV-QGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 127 QERTLSRKAKELITAIELEKTYTKDEILALYLNTVYFGSGAYGIEAAANTYFGKKASELTIPESASLIATLKNPTAYNPA 206
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 908399932 207 KNPSTALGRRNLIIGLME 224
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
24-625 |
2.63e-79 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 271.26 E-value: 2.63e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 24 KGLPSLEELENPK--------PNLASLVYSEDGvllhkfflENRTFVPLKSISKWVPKALIATEDVAFYQHWGVDLRRLT 95
Cdd:PRK09506 176 DRLATIVNLDNNRqfgffrldPRLITMLQSPNG--------EQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIG 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 96 LAMGENIIKGRTRwHGASTITQQLAKNLFLTQERTLSRKAKELITAIELEKTYTKDEILALYLNTVYFG-SGA---YGIE 171
Cdd:PRK09506 248 RAVLANLTAGRTV-QGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDRILELYLNEVYLGqSGDdqiRGFP 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 172 AAANTYFGKKASELTIPESASLIATLKNPTAYNPAKNPSTALGRRNLIIGLMEKEGFITHAQAVKAKATPVTLH-----Y 246
Cdd:PRK09506 327 LASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLSARPLGVQpkggvI 406
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 247 TPSthhglaPYFTEYIRQNIKTSSQlDGVNVYSdGLTIQTTLDSRMQryaqeaiaqqaaalqaefdkrwtcsDALKKQFi 326
Cdd:PRK09506 407 SPQ------PAFMQMVRQELQAKLG-DKVKDLS-GVKIFTTLDPVSQ-------------------------DAAEKAV- 452
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 327 kespqyrelvnEEGVaPATALSKLLADkvfvknllhdksrVQMALISLDPTNGHVKAWVGGTN--FSpddyryQFDHVWQ 404
Cdd:PRK09506 453 -----------EEGI-PALKKQRKLSD-------------LETAMVVVDRFSGEVRAMVGGSEpqFA------GYNRAMQ 501
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 405 AKRQPGSTFKPFVYSAAIDQgiPANYR----ILDQPLALRGGDGSVWMARNSEGQSGGMTTLRDALRRSLNQVTIRLAYQ 480
Cdd:PRK09506 502 ARRSIGSLAKPATYLTALSQ--PDKYRlntwIADAPISLRQPNGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMA 579
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 481 FLTPsEIISYARRMGI-TTPMQPNLSIALGTSEVSPLVLAQAFTTFANNGTWSEPLPVTKVLDKRGGLITEHKPVSHFGL 559
Cdd:PRK09506 580 LGLP-AVTDTWIKLGVpKDQLNPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAV 658
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 908399932 560 DPASNFVMVTMLKDVIDRGTGIAVRARYGfDAEAGGKTGTTQSMRDAWFAGFTPQLVTVVWAGFDD 625
Cdd:PRK09506 659 PAQAAYLTLYTMQQVVQRGTGRQLGAKYP-NLHLAGKTGTTNDLVDSWFAGIDGKEVTITWVGRDN 723
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
37-697 |
5.41e-68 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 238.98 E-value: 5.41e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 37 PNLASLVYSEDGvllhkfflENRTFVPLKSISKWVPKALIATEDVAFYQHWGVDLRRLTLAMGENIIKGRTrWHGASTIT 116
Cdd:PRK14850 143 PKLIAMLYSPEG--------KKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHT-IQGGSTLT 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 117 QQLAKNLFLTQERTLSRKAKELITAIELEKTYTKDEILALYLNTVYFGSGA----YGIEAAANTYFGKKASELTIPESAS 192
Cdd:PRK14850 214 QQLVKNLFLTNTRSLWRKINEIYMALILDRFYSKDRILELYLNEVYLGQDGneqiRGFPLASIYYFGRPINELNLDQYAL 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 193 LIATLKNPTAYNPAKNPSTALGRRNLIIGLMEKEGFITHAQAVKAKATPVTLHyTPSTHHGLAPYFTEYIRQNIKTSSQL 272
Cdd:PRK14850 294 LVGMVKGASLYNPWTNPNLTLKRRNLVLFLLYKQKVITRKLYKDLCSRPLNVQ-SKGNIISSHPAFIQLVCEEFHKKIHY 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 273 DGVNVysDGLTIQTTLDSRMQRyaqeaiaqqaaalqaefdkrwTCSDALKKQfIKESPQYRELVNEEGvapatalsklla 352
Cdd:PRK14850 373 PFKNF--SGTKIFTTLDYISQN---------------------AAEQAVKIG-IPILKRKKRLKDLEV------------ 416
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 353 dkvfvknllhdksrvqmALISLDPTNGHVKAWVGGTN--FSpddyryQFDHVWQAKRQPGSTFKPFVYSAAIDQgiPANY 430
Cdd:PRK14850 417 -----------------AMVIIDRFSGEVRALIGSSKpeFN------GYNRALKARRSIGSLSKPITYLTALSQ--PEKY 471
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 431 R----ILDQPLALRGGDGSVWMARNSEGQSGGMTTLRDALRRSLNQVTIRLAYQfLTPSEIISYARRMGITTP-MQPNLS 505
Cdd:PRK14850 472 HlntwISDTPISIKLDNGQYWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSIN-LGLKKLVDSWILLGISSNyITPLPS 550
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 506 IALGTSEVSPLVLAQAFTTFANNGTWSEPLPVTKVLDKRGGLITEHKPVSHFGLDPASNFVMVTMLKDVIDRGTGIAVRA 585
Cdd:PRK14850 551 ISLGAINLTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSGTAKSLGT 630
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 586 RYGfDAEAGGKTGTTQSMRDAWFAGFTPQLVTVVWAGFDDERvhfTSMSYgqGARAALPAWASFMKkcYDDPELHLenry 665
Cdd:PRK14850 631 IFK-EFSLAGKTGTTNNLVDSWFVGIDGKQVVITWIGRDNNH---TTKLY--GSSGAMKIYKRYLQ--YQNPVPLV---- 698
|
650 660 670
....*....|....*....|....*....|..
gi 908399932 666 FTMPDNVIAVPISagsgDQGDLFNRDVYVEYF 697
Cdd:PRK14850 699 LKAPNNINMFYIN----NLGELFCKKGNNQYN 726
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
35-625 |
3.80e-39 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 155.24 E-value: 3.80e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 35 PKPNLASLVYSEDGVLLHKFFLEN---RTFVPLKSISKWVPKALIATEDVAFYQHWGVDLRRLTLAMGENIIKGRTRwHG 111
Cdd:PRK11240 35 HEVNPARVVVAEDGTPLWRFADADgiwRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVI-SG 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 112 ASTITQQLAKnLFLTQERTLSRKAKELITAIELEKTYTKDEILALYLNTVYFGSGAYGIEAAANTYFGKKASELTIPESA 191
Cdd:PRK11240 114 GSTLTMQVAR-LLDPHPRTFGGKIRQLWRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAA 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 192 SLIATLKNPTAYNPAKNPSTALGRRNLIIGLMEKEGFITHAQAVKAKATPVTLhyTPSTHHGLAPYFTEyiRQNIKTSSQ 271
Cdd:PRK11240 193 LLAVLPQAPSRLRPDRWPERAEAARNKVLERMAEQGVWSAEQVKESREEPVWL--APRQMPQLAPLFAR--MMLGKSKSD 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 272 LdgvnvysdgltIQTTLDSRMQRyaqeaiaqqaaalqaefdkrwtcsdalkkqfikespQYREL-VNEEGVAPAtalskl 350
Cdd:PRK11240 269 K-----------IVTTLDAGLQR------------------------------------RLEDLaLNWKGRLPP------ 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 351 ladkvfvknllhdksRVQMALISLDPTNGHVKAWVGGTNFSpDDYRyqFDHV--WQAKRQPGSTFKPFVYSAAIDQGI-- 426
Cdd:PRK11240 296 ---------------RSSLAMIVVDHTDMAVRGWVGSVDLN-DDSR--FGHVdmVNAIRSPGSVLKPFVYGLALDDGLih 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 427 PANyriLDQPLALRGGDgsvwmARNSEGQSG--GMTTLRDALRRSLNQVTIRL--AYqflTPSEIISYARRMG--ITTPM 500
Cdd:PRK11240 358 PAS---LLQDVPRRTGD-----YRPGNFDSGfhGPVSMSEALVRSLNLPAVQVleAY---GPKRFAAKLRNVGlpLYLPA 426
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 501 --QPNLSIALGTSEVSPLVLAQAFTTFANNGTwSEPL---PVTKVLDKRgglitehkpvshfGLDPASNFVMVTMLKDvi 575
Cdd:PRK11240 427 gaEPNLSLILGGAGARLEDMVAAYSAFARHGK-AAKLrlqPDDPLLERP-------------LMSPGAAWIIRRIMAD-- 490
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 908399932 576 drgtgiavRARYGFDAE------AGGKTGTTQSMRDAWFAGFTPQLVTVVWAGFDD 625
Cdd:PRK11240 491 --------EAQPLPDAAlprvvpLAWKTGTSYGYRDAWAIGVNARYVIGIWTGRPD 538
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
59-221 |
7.02e-37 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 137.98 E-value: 7.02e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 59 RTFVPLKSISKWVPKALIATEDVAFYQHWGVDLRRLTLAMGENIIKGRTrWHGASTITQQLAKNLFLTQERTLSRKAKEL 138
Cdd:TIGR02070 55 HRWRPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKV-VRGGSTISQQLAKNLFLWSGRSYLRKGLEA 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 139 ITAIELEKTYTKDEILALYLNTVYFGSGAYGIEAAANTYFGKKASELTIPESASLIATLKNPTAYNPAKnPSTALGRRNL 218
Cdd:TIGR02070 134 WATWMLETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENR-PGPYVRRKAT 212
|
...
gi 908399932 219 IIG 221
Cdd:TIGR02070 213 WIL 215
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
56-233 |
4.02e-35 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 133.39 E-value: 4.02e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 56 LENR-TFVPLKSISKWVPKALIATEDVAFYQHWGVDLRRLTLAMGENIIKGRTRwhGASTITQQLAKNLFLTQERTLSRK 134
Cdd:PRK13481 41 IENKsSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRDVQ--GGSTITQQVVKNYFYDNERSFTRK 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 135 AKELITAIELEKTYTKDEILALYLNTVYFGSGAYGIEAAANTYFG-------KKASELTIPESASLIATLKNPTAYNPAK 207
Cdd:PRK13481 119 VKELFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGttvnknsTTMSHITVLQSAILASKVNAPSVYNIND 198
|
170 180
....*....|....*....|....*.
gi 908399932 208 NPSTALGRRNLIIGLMEKEGFITHAQ 233
Cdd:PRK13481 199 MSENFTQRVSTNLEKMKQQNYINETQ 224
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
280-619 |
2.24e-27 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 117.62 E-value: 2.24e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 280 DGLTIQTTLDSRMQRYaqeaiaqqaaalqaefdkrwtCSDALKKQFIKESPQyrelvneegvapatalsklladkvfvkn 359
Cdd:COG0768 217 PGKDLVLTIDSDLQKI---------------------AEEALKKAVEEYKAK---------------------------- 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 360 llhdksrvQMALISLDPTNGHVKAWVGGTNFSPDDYRYQFDHVW-----QAKRQPGSTFKPFVYSAAIDQG-IPANYRIL 433
Cdd:COG0768 248 --------SGAVVVMDPKTGEILAMASYPSFDPNLFVGGPDEPLrnravQGTYEPGSTFKPFTAAAALEEGvITPDTTFD 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 434 DqplalrggDGSVWMA----RNSEGQSGGMTTLRDALRRSLNQVTIRLAYQfLTPSEIISYARRMGITTPM--------- 500
Cdd:COG0768 320 C--------PGYYRVGgrtiRDWDRGGHGTLTLTEALAKSSNVGFYKLALR-LGIDKLYDYLKKFGLGQKTgidlpgeas 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 501 -------------QPNLSIALGTSeVSPLVLAQAFTTFANNGTWSEPLPVTKVLDKRGGLITEHKPVSHFGLDPASNFVM 567
Cdd:COG0768 391 gllpspkrwypgeTATMSIGQGLS-VTPLQLAQAYAAIANGGVLVKPHLVKEIVDPDGEVVKEEPEVLRRVISPETAETV 469
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 908399932 568 VTMLKDVIDRGTGIAVRARyGFDAEAGGKTGTTQ-----------SMRDAWFAGFT----PQLVTVV 619
Cdd:COG0768 470 REGMEGVVNEPGGTARRAA-IPGYRVAGKTGTAQvvdignggyykGRHIASFVGFApadnPRYAVAV 535
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
369-614 |
1.33e-23 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 101.72 E-value: 1.33e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 369 MALISLDPTNGHVKAWVGGTNFSPDDYRYQF-DHVWQAKRQPGSTFKPFVYSAAIDQGIPANYRILDQPLALRGGDGSVw 447
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYDPNGFIGPLrNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIFDWPGKQQGGKSI- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 448 maRNSEGQSGGMTTLRDALRRSLNQVTIRLAyQFLTPSEIISYARRMGITTPM------------------QPNLSIALG 509
Cdd:pfam00905 80 --GDWNQDQVGIGTLRQALEYSSNWYMQKLA-QKLGADKLRSYLKKFGYGNKTgiglpgenagyltpywleGATASFGIG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 510 TSeVSPLVLAQAFTTFANNGTWSEPLPVTKVLDKRGGLITEHKPVShfgldpASNFVMVT-MLKDVIDRGTGIAVRARYG 588
Cdd:pfam00905 157 LT-ITPLQQAQAYAAIANGGKLVPPHLVKSIEDKVDPKVLNKLPIS------KSTAEKVKdMLRLVVNDGTGTGTAAVPG 229
|
250 260 270
....*....|....*....|....*....|....*..
gi 908399932 589 FDaeAGGKTGTTQSM-----------RDAWFAGFTPQ 614
Cdd:pfam00905 230 YK--VAGKTGTAQVAgpkgggyydgaQIGWFVGYAPA 264
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
370-619 |
3.63e-21 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 98.36 E-value: 3.63e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 370 ALISLDPTNGHVKAWVGGTNFSP-----------------DDYRYQFDHVWQAKRQPGSTFKPFVYSAAIDQG-IPANYR 431
Cdd:TIGR03423 250 AVVVMDPRTGEILAMVSTPSFDPnlfvdgisskdykallnDPDRPLLNRAIQGVYPPGSTFKPVVALAALEEGvITPETR 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 432 ILDqPLALRGGdGSVWmaRNSEGQSGGMTTLRDALRRSLNQVTIRLAYQfLTPSEIISYARRMGITTPM----------- 500
Cdd:TIGR03423 330 IYC-PGYFQLG-GRRF--RCWKRGGHGRVDLRKAIEESCDVYFYQLALR-LGIDKIAEYAKRFGFGQKTgidlpgeksgl 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 501 ------------QP-------NLSIALGTSEVSPLVLAQAFTTFANNGTWSEPLPVTKVLDKRGGLITEHKP--VSHFGL 559
Cdd:TIGR03423 405 vpsrewkrkrfgQPwypgdtlNVSIGQGYVLVTPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRTEPevLRPLPI 484
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908399932 560 DPASNFVMVTMLKDVIDRGTGIAVRARYGFDAEAGGKTGTTQ-----------------SMRD-AWFAGFTP----QLVT 617
Cdd:TIGR03423 485 SPENLDVVREGMRDVVNGPGGTARRARLGLPYKMAGKTGTAQvvslkqgekydaeqipeRLRDhALFVAFAPydnpKIAV 564
|
..
gi 908399932 618 VV 619
Cdd:TIGR03423 565 AV 566
|
|
| |
