|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
5-393 |
0e+00 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 780.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 5 DDLEYQLDTLAIRTGHTRSFEGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAV 84
Cdd:PRK08133 1 DDDSLGFDTLAVRAGQLRSPFGEHSEALFLTSSFVFESAAEAAARFAGEEPGNIYSRFTNPTVTMFQERLAALEGAEACV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 85 ATSSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLA 164
Cdd:PRK08133 81 ATASGMAAILAVVMALLQAGDHVVSSRSLFGSTVSLFEKIFARFGIETTFVDLTDLDAWRAAVRPNTKLFFLETPSNPLT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 165 EIADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFGVVRTLGPS 244
Cdd:PRK08133 161 ELADIAALAEIAHAAGALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELMEEVFGFLRTAGPT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 245 MSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAW 324
Cdd:PRK08133 241 LSPFNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLPSHPQHELAKRQQKGGGAIVSFEVKGGREAAW 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 908704900 325 KVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:PRK08133 321 RVIDATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVGLEDVADIKADLARGLA 389
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
9-395 |
0e+00 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 603.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 9 YQLDTLAIRTGH-TRSFEGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATS 87
Cdd:COG0626 1 MGPATRAVHAGRdPDPQTGAVSPPIYLTSTFVFPSAEALAARFAGEEGGYIYSRYGNPTRRALEEALAALEGGEAALAFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 88 SGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIA 167
Cdd:COG0626 81 SGMAAISAVLLALLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 168 DIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLL-EEVFGVVRTLGPSMS 246
Cdd:COG0626 161 DIAAIAAIAHAAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELaERLRFLQNALGAVLS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 247 PFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWKV 326
Cdd:COG0626 241 PFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKGGREAARRF 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 908704900 327 IDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLDLI 395
Cdd:COG0626 321 LDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLEDVDDLIADLEQALAAL 389
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
12-392 |
0e+00 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 559.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 12 DTLAIRTGHTRSFEGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 91
Cdd:TIGR01325 1 ATLAVRGGMLRSGFEETAEALYLTSGYVYDSAAVAAKRFAGELPGFVYSRYGNPTVSVFEERLALLEGAEAAVATASGMA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 92 AILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQA 171
Cdd:TIGR01325 81 AIFAALMALLGAGDHVVASRSLFGSCFVVCSEILPRFGVQTVFVDGTDLSAWEAALKPNTKAVFVETPSNPLQELVDIAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 172 LADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEE-VFGVVRTLGPSMSPFNA 250
Cdd:TIGR01325 161 VAELAHAAGAKVVVDNVFATPLLQQPLKLGADVVVYSATKHIDGQGRVLGGAILGSEEYMDEpVQKLLRHTGPAMSPFNA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 251 WVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGeREGAWKVIDNT 330
Cdd:TIGR01325 241 WVLLKGLETLAIRVQHQNASALAIAEWLNGHPSVQWVYYPGLPSHPQHELAKRQMSGGGTVVTFDLDC-RQAAFKVLDAM 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 908704900 331 KFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:TIGR01325 320 RLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGDGLVRLSVGLEDVDDLIADIDRAL 381
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
12-393 |
2.61e-177 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 498.30 E-value: 2.61e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 12 DTLAIRTGHTRSF-EGEHGEPIFLTSSFVYenaeeaaaKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGM 90
Cdd:pfam01053 1 DTLAVHAGQRPDPqTGAVSVPIYLTSTYVF--------DFAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGM 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 91 GAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQ 170
Cdd:pfam01053 73 AAITAAILALLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 171 ALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQ-LLEEVFGVVRTLGPSMSPFN 249
Cdd:pfam01053 153 AIAKLAKKHGILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEeLGKELYFLQNATGAVLSPFD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 250 AWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWKVIDN 329
Cdd:pfam01053 233 AWLLLRGLKTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFELKGGLEAAKKFLDN 312
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 908704900 330 TKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:pfam01053 313 LKLFSLAVSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQALE 376
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
8-393 |
3.24e-172 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 487.23 E-value: 3.24e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 8 EYQLDTLAIRTGHTRsfeGEHGE----PIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERA 83
Cdd:COG2873 5 KYGFETLALHAGQEP---DPTTGaravPIYQTTSYVFDDAEHAADLFALKEPGNIYTRIMNPTTDVLEKRIAALEGGVAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 84 VATSSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPL 163
Cdd:COG2873 82 LATASGQAAITLAILNLAEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNPA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 164 AEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVV--GN---------HQLLE 232
Cdd:COG2873 162 LDVLDIEAIAEIAHEHGVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIVdgGNfdwaangkfPELTE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 233 -----------EVFG-----------VVRTLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYA 290
Cdd:COG2873 242 pdpsyhglvytEAFGnaafitkarvqLLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWVNYP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 291 GLPAHEGHELAAKQ-QTGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQE 369
Cdd:COG2873 322 GLPSHPYHELAQKYlPKGAGGVLTFGLKGGREAGKKFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAAGVTP 401
|
410 420
....*....|....*....|....
gi 908704900 370 GLIRVSVGLEDINDIIRDISRGLD 393
Cdd:COG2873 402 DLIRLSVGIEDIDDIIADLDQALA 425
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
31-393 |
9.62e-170 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 479.01 E-value: 9.62e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 31 PIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSVTMAYLKAGDHVICS 110
Cdd:cd00614 6 PIYQTSTFVFPSPAEAADLFALREGGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTVLLALLKAGDHVVAS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 111 RAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 190
Cdd:cd00614 86 DDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEHGALLVVDNTFA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 191 TPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGN-HQLLEEVFGVVRTLGPSMSPFNAWVFLKGLETLRLRMKAHCE 269
Cdd:cd00614 166 TPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSgEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRMERHSE 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 270 SAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHP 349
Cdd:cd00614 246 NALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELKGGLEAAKKFLNALKLFSLAVSLGGVESLVEHP 325
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 908704900 350 ATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:cd00614 326 ASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQALK 369
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
9-393 |
4.35e-155 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 443.04 E-value: 4.35e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 9 YQLDTLAIRTGHTRSFEGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSS 88
Cdd:PRK07504 9 WRPATRLVHSGTLRSQFGETSEALFLTQGFVYDTAEAAEARFKGEDPGFIYSRYSNPTVDMFEKRMCALEGAEDARATAS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 89 GMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIAD 168
Cdd:PRK07504 89 GMAAVTAAILCQVKAGDHVVAARALFGSCRYVVETLLPRYGIESTLVDGLDLDNWEKAVRPNTKVFFLESPTNPTLEVID 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 169 IQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEE-VFGVVRTLGPSMSP 247
Cdd:PRK07504 169 IAAVAKIANQAGAKLVVDNVFATPLFQKPLELGAHIVVYSATKHIDGQGRCLGGVVLSDKAWIEEhLQDYFRHTGPSLSP 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 248 FNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWKVI 327
Cdd:PRK07504 249 FNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVIYPGRADHPQADIIAKQMTGGSTLVAFELKGGKEAAFRFL 328
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 908704900 328 DNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:PRK07504 329 NALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELGISEGFLRLSAGLEDTDDLIEDLAAALK 394
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
12-392 |
8.86e-152 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 434.55 E-value: 8.86e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 12 DTLAIRTGHTRSFEGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 91
Cdd:PRK07810 17 ATIGVRGGLLRSGFEETAEALYLTSGYVYESAAAAEAAFTGELDRFVYSRYGNPTVSMFEERLRLIEGAEACFATASGMS 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 92 AILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQA 171
Cdd:PRK07810 97 AVFTALGALLGAGDRLVAARSLFGSCFVVCNEILPRWGVETVFVDGEDLSQWEEALSVPTQAVFFETPSNPMQSLVDIAA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 172 LADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEevfGVVRTL----GPSMSP 247
Cdd:PRK07810 177 VSELAHAAGAKVVLDNVFATPLLQRGLPLGADVVVYSGTKHIDGQGRVLGGAILGDREYID---GPVQKLmrhtGPALSA 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 248 FNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGE----REGA 323
Cdd:PRK07810 254 FNAWVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRYPFLPSHPQYDLAKRQMSGGGTVVTFELDAPedaaKKRA 333
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 908704900 324 WKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK07810 334 FEVLDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGLGDGVVRLSVGLEDTDDLIADLDRAL 402
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
11-392 |
1.44e-143 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 414.45 E-value: 1.44e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 11 LDTLAIRTGHT-RSFEGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSG 89
Cdd:TIGR01326 2 FETLQLHAGQEpDPTTGSRAVPIYQTTSYVFDSTEHAAALFGLQEPGNIYSRLMNPTTDVLEQRIAALEGGVAALAVASG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 90 MGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADI 169
Cdd:TIGR01326 82 QAAITYAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINVLDI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 170 QALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVV--GN------------------HQ 229
Cdd:TIGR01326 162 EAIAEVAHRHGIPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVdgGKfdwnngrfplfttpdpsyHG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 230 L-LEEVFG-----------VVRTLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEG 297
Cdd:TIGR01326 242 LvFTETLGnpafilkarvqLLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGLASHPH 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 298 HELAAKQQT-GFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSV 376
Cdd:TIGR01326 322 HALAKKYLPkGFGAVLSFEIKGGREAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGLIRLSV 401
|
410
....*....|....*.
gi 908704900 377 GLEDINDIIRDISRGL 392
Cdd:TIGR01326 402 GIENIDDIIADLEQAL 417
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
13-395 |
3.19e-138 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 399.97 E-value: 3.19e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 13 TLAIRTGHTRSFE-GEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 91
Cdd:PRK06234 11 TKAIHGGHIGDKQfGSLATPIYQTSTFIFDSAEQGGRRFAGEESGYIYSRLGNPTSTEVENKLALLEGGEAAVVAASGMG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 92 AILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQA 171
Cdd:PRK06234 91 AISSSLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLKVTDIKA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 172 LADIAHAN--GALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEV--FGVVRTLGPSMSP 247
Cdd:PRK06234 171 ISNIAHENnkECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGKEEFINQVklFGIKDMTGSVIGP 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 248 FNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWKVI 327
Cdd:PRK06234 251 FEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELKGGVEEGKVVM 330
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 908704900 328 DNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLDLI 395
Cdd:PRK06234 331 NNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQALDLI 398
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
13-393 |
1.21e-133 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 388.09 E-value: 1.21e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 13 TLAIRTGHTRSFE-GEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 91
Cdd:TIGR01328 6 TRAIHAGYPPKDQfGALTPPIYQTSTFVFDSCEQGGNRFAGQESGYIYSRLGNPTVSNLEGRIAFLEGTEAAVATSSGMG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 92 AILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQA 171
Cdd:TIGR01328 86 AIAATLLTILKAGDHLISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKLIDMER 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 172 LADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEV--FGVVRTLGPSMSPFN 249
Cdd:TIGR01328 166 VCRDAHSQGVKVIVDNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQIrmVGIKDMTGSVISPFD 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 250 AWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWKVIDN 329
Cdd:TIGR01328 246 AWLILRGLKTLNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGHDIAAKQMRMGGGMITFELKGGFAGAKKLLNN 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 908704900 330 TKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:TIGR01328 326 LKLIRLAVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDLIADLKQALD 389
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
13-393 |
5.08e-126 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 369.13 E-value: 5.08e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 13 TLAIRTGHT-RSFEGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 91
Cdd:PRK07503 12 TRAIHHGYDpLDHGGALVPPVYLTATFAFPTAEYGAECFAGEEEGHFYSRISNPTLALLEQRMASLEGGEAAVALASGMG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 92 AILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQA 171
Cdd:PRK07503 92 AITATLWTLLRPGDEVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRLVDIAA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 172 LADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEV--FGVVRTLGPSMSPFN 249
Cdd:PRK07503 172 VAEIAHGAGAKVVVDNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRIrlEGLKDMTGAVMSPFD 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 250 AWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWKVIDN 329
Cdd:PRK07503 252 AFLLMRGLKTLALRMDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELKGGIAAGRRFMNA 331
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 908704900 330 TKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:PRK07503 332 LQLFARAVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALD 395
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
8-395 |
1.94e-125 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 367.24 E-value: 1.94e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 8 EYQLDTLAIRTGHTrsfEGEH----GEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERA 83
Cdd:PRK06767 3 KKHMETALIHHGYT---SEEHkgslTPPLFQTSTFTFETAQQGEASFAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 84 VATSSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPL 163
Cdd:PRK06767 80 LAFGSGMAAISATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 164 AEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFGVVRT-LG 242
Cdd:PRK06767 160 MKLIDLKQVIRVAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKdIG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 243 PSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYaglPAhegHELAAKQQTGFGGIVSFVVKGEREG 322
Cdd:PRK06767 240 GIMAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWY---PE---GELASRQMKRGGGVISFSIKGGKEE 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 908704900 323 AWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLDLI 395
Cdd:PRK06767 314 TQAFINDLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALKKI 386
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
1-393 |
4.01e-122 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 358.57 E-value: 4.01e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 1 MNQSDDLEYQ-LDTLAIRTGHT-RSFEGEHGEPIFLTSSFvyenAEEAAAKFSGqvqGNIYSRFTNPTVSMFEKRLAALD 78
Cdd:PRK07811 2 EDMSDHHANQgFATRAIHAGYEpDPATGAVNPPIYASSTF----AQDGVGGLRG---GYEYARTGNPTRTALEEQLAALE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 79 GAERAVATSSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVES 158
Cdd:PRK07811 75 GGAYGRAFSSGMAATDCLLRAVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVET 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 159 PSNPLAEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFGVV 238
Cdd:PRK07811 155 PTNPLLSITDIAALAELAHDAGAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 239 R-TLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVK 317
Cdd:PRK07811 235 QnGAGAVPGPFDAYLTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRLA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 318 GEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGklsadakAAAGIQ----EGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:PRK07811 315 GGEEAARDFCARTKVFTLAESLGGVESLIEHPSAMTHA-------STAGSQlevpDDLVRLSVGIEDVADLLADLEQALG 387
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
31-395 |
4.94e-122 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 358.67 E-value: 4.94e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 31 PIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSVTMAYLKAGDHVICS 110
Cdd:PRK08249 30 PVVLSVAYGYDDIDEWYDVALGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFSTGMAAISNTLYTFLKPGDRVVSI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 111 RAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 190
Cdd:PRK08249 110 KDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIVDIERLAAAAKKVGALVVVDNTFA 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 191 TPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFGVVRTLGPSMSPFNAWVFLKGLETLRLRMKAHCES 270
Cdd:PRK08249 190 TPINQNPLALGADLVIHSATKFLSGHADALGGVVCGSKELMEQVYHYREINGATMDPMSAYLILRGMKTLKLRVRQQQES 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 271 AQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPA 350
Cdd:PRK08249 270 AMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVLKGGMDTVKRLLPKLRYAHRAANLGAVETIYGPAR 349
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 908704900 351 TTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLDLI 395
Cdd:PRK08249 350 TTSHVENTLEERAALGIPEGLVRISVGIEDTEDLIADLEQAFAHL 394
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
12-392 |
6.33e-118 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 349.81 E-value: 6.33e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 12 DTLAIRTG-HTRSFEGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGM 90
Cdd:PRK08134 10 DTLALHAGaAPDPATGARAVPIHLTTSFVFRDSDHAAALFNLERAGHVYSRISNPTVAVLEERVAALEGGVGAIATASGQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 91 GAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQ 170
Cdd:PRK08134 90 AALHLAIATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVLDIP 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 171 ALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVV---------------------GNHQ 229
Cdd:PRK08134 170 TVAAIAHEAGVPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLVdggrfdweasgkfpeltepyaGFHG 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 230 L-LEEVFGV-----------VRTLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEG 297
Cdd:PRK08134 250 MvFAEESTVaafllrarregLRDFGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPELESHPD 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 298 HELAAK-QQTGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSV 376
Cdd:PRK08134 330 HALAKRlLPRGAGSVFSFDLKGGRAAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIGEGTIRLSI 409
|
410
....*....|....*.
gi 908704900 377 GLEDINDIIRDISRGL 392
Cdd:PRK08134 410 GLEDADDLIDDLKRAL 425
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
31-392 |
5.79e-117 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 347.12 E-value: 5.79e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 31 PIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAIlsvTMAYL---KAGDHV 107
Cdd:PRK07812 35 PIYQTTSYTFDDTDHAAALFGLAEPGNIYTRIMNPTQDVVEQRIAALEGGVAALLLASGQAAE---TFAILnlaGAGDHI 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 108 ICSRAVFGSVVALFEKYIAKFGVDITFV-DLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVD 186
Cdd:PRK07812 112 VSSPRLYGGTYNLFHYTLPKLGIEVSFVeDPDDLDAWRAAVRPNTKAFFAETISNPQIDVLDIPGVAEVAHEAGVPLIVD 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 187 NSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVV---------GNHQLLEE----VFGVV--------------- 238
Cdd:PRK07812 192 NTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIVdggtfdwtqGRFPGFTTpdpsYHGVVfaelgppayalkarv 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 239 ---RTLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAK-QQTGFGGIVSF 314
Cdd:PRK07812 272 qllRDLGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGLPSSPWYERAKRlAPKGTGAVLSF 351
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 908704900 315 VVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK07812 352 ELAGGVEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLVRLAVGIEGIDDILADLEAGF 429
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
4-392 |
7.05e-114 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 339.13 E-value: 7.05e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 4 SDDLEYQLDTLAIRTGHT-RSFEGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAER 82
Cdd:PRK08248 2 SEERTFRLETLAIHAGQEiDPTTGSRAVPIYQTTSYGFRDSEHAANLFSLKEFGNIYTRIMNPTTDVFEKRIAALEGGIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 83 AVATSSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNP 162
Cdd:PRK08248 82 ALAVSSGQAAITYSILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGNP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 163 LAEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVV----------GNHQLLE 232
Cdd:PRK08248 162 KGDVLDIEAVAAIAHEHGIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVdsgkfdwkgsGKFPGLT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 233 E----VFGVV-------------------RTLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYY 289
Cdd:PRK08248 242 EpdpsYHGLVytdavgeaayitkarvqllRDLGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSY 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 290 AGLPAHEGHELAAKQ-QTGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQ 368
Cdd:PRK08248 322 PGLPSHPSYELAKKYlPKGQGAILTFGIKGGVEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVT 401
|
410 420
....*....|....*....|....
gi 908704900 369 EGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK08248 402 PGLVRLSVGTEAIDDILDDLRQAI 425
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
11-395 |
1.84e-111 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 332.83 E-value: 1.84e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 11 LDTLAIRTG-HTRSFEGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSG 89
Cdd:PRK05994 8 FATLAVHAGaQPDPTTGARATPIYQTTSFVFNDADHAASLFGLQAFGNIYTRITNPTNAVLEERVAALEGGTAALAVASG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 90 MGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADI 169
Cdd:PRK05994 88 HAAQFLVFHTLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTVTDI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 170 QALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVV----------GNHQLL-------- 231
Cdd:PRK05994 168 AAIAEVAHRAGLPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIIVdggtfdwsksGKYPMLseprpeyh 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 232 ----EEVFGV-----------VRTLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHE 296
Cdd:PRK05994 248 glvlHETFGNfafaiaarvlgLRDLGPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGLPDDP 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 297 GHELAAK-QQTGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVS 375
Cdd:PRK05994 328 YHALAQKySPKGAGAVFTFGLKGGYEAGVKLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVVRLS 407
|
410 420
....*....|....*....|
gi 908704900 376 VGLEDINDIIRDISRGLDLI 395
Cdd:PRK05994 408 IGIEDVDDIIADLEQALAKA 427
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
31-393 |
3.31e-110 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 327.84 E-value: 3.31e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 31 PIFLTSSFVYENAeeaaakfsGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSVTMaYLKAGDHVICS 110
Cdd:PRK07671 24 PIYQVSTYKQEAV--------GKHQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITAVMM-LFSSGDHVILT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 111 RAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 190
Cdd:PRK07671 95 DDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTIAKEKGLLTIVDNTFM 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 191 TPVLQQPLKFGADLVIYSATKYLDGQGRALGG-AVVGNHQLLEEVFGVVRTLGPSMSPFNAWVFLKGLETLRLRMKAHCE 269
Cdd:PRK07671 175 TPYWQSPISLGADIVLHSATKYLGGHSDVVAGlVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLRGLKTLGIRMEEHET 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 270 SAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVkGEREGAWKVIDNTKFISITGNLGDVKSTITHP 349
Cdd:PRK07671 255 NSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDV-GSEETANKVLERLQYFTLAESLGAVESLISIP 333
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 908704900 350 ATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:PRK07671 334 SQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQALA 377
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
2-395 |
7.64e-106 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 318.74 E-value: 7.64e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 2 NQSDDLEYQLDTLAIRTGHTRSFE-GEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGA 80
Cdd:PRK05613 5 DNSNADQWGFETRSIHAGQSVDSDtSARNLPIYQTTSYVFDSAEHAKQRFALEDLGPIYSRLTNPTVEALENRIASLEGG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 81 ERAVATSSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDlcDLDD---WKNAVRPETKLLFVE 157
Cdd:PRK05613 85 VHAVAFASGQAAETAAILNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVE--NPDDpesWQAAVQPNTKAFFGE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 158 SPSNPLAEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVV--GNHQLLEE-- 233
Cdd:PRK05613 163 TFANPQADVLDIPAVAEVAHRNQVPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIdgGKFDWTVErd 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 234 ---VF-----------------------------GVVRTLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTH 281
Cdd:PRK05613 243 gkpVFpyfvtpdpayhglkyadlgapafglkaraGLLRDTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNH 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 282 EKVEKVYYAGLPAHEGHelAAKQQTGF---GGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLS 358
Cdd:PRK05613 323 EKVAKVNFAGLKDSPWY--ATKEKLGLkytGSVLSFDIKGGKDEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSD 400
|
410 420 430
....*....|....*....|....*....|....*..
gi 908704900 359 ADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLDLI 395
Cdd:PRK05613 401 EAGLARAGITQATVRLSVGIEDIDDIIADLEGGFAAI 437
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
13-392 |
8.47e-101 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 304.29 E-value: 8.47e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 13 TLAIRtGHTRSFE-GEHGEPIFLTSSFvyenAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 91
Cdd:PRK08574 5 TDAVR-GYRGSDPyGSLQPPIYLTALF----RQEGEAYPSDRGFDLKYSREENPTLRPLEEALAKLEGGVDALAFNSGMA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 92 AILSVTMAYLKAGDHVICSRAVFGSVVALFEKyIAKFGVDITFVdLCDLDDWKNAVR-PETKLLFVESPSNPLAEIADIQ 170
Cdd:PRK08574 80 AISTLFFSLLKAGDRVVLPMEAYGTTLRLLKS-LEKFGVKVVLA-YPSTEDIIEAIKeGRTKLVFIETMTNPTLKVIDVP 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 171 ALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGG-AVVGNHQLLEEVFGVVRTLGPSMSPFN 249
Cdd:PRK08574 158 EVAKAAKELGAILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGvAVAWSGEFLEELWEWRRRLGTIMQPFE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 250 AWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAK--QQTGFGGIVSFVVKGEREGAWKVI 327
Cdd:PRK08574 238 AYLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKRlfGKDLYGGVVSFRVKGGRDAVLKFL 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 908704900 328 DNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK08574 318 RSLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDLDQAL 382
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
10-393 |
1.18e-97 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 297.58 E-value: 1.18e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 10 QLDTLAIRTGHTRSFEGEH-GEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSS 88
Cdd:PRK06084 2 KLETLAIHAGYSPDPTTKAvAVPIYQTTSYAFDDTQHGADLFDLKVPGNIYTRIMNPTNDVLEQRVAALEGGVGALAVAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 89 GMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIAD 168
Cdd:PRK06084 82 GMAAITYAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNIID 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 169 IQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVV-------GNHQ----LLE----- 232
Cdd:PRK06084 162 IQALADAAHRHGVPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVVdsgkfpwAEHKerfaLLNtpdps 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 233 -------EVFGV-----------VRTLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPA 294
Cdd:PRK06084 242 yhgvtytEAFGPaafigrcrvvpLRNMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGLPD 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 295 HEGHELAAKQQTGF-GGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIR 373
Cdd:PRK06084 322 HPEHELARRYMGGKpASILSFGIKGGQAAGARFIDALKLVVRLVNIGDAKSLACHPASTTHRQLNDEELEKAGVSRDMVR 401
|
410 420
....*....|....*....|
gi 908704900 374 VSVGLEDINDIIRDISRGLD 393
Cdd:PRK06084 402 LSIGIEHIDDIIADLAQALD 421
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
31-392 |
1.47e-97 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 295.59 E-value: 1.47e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 31 PIFLTSSFVYENAEeaaaKFSgqvqgniYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSVTMAYLKAGDHVICS 110
Cdd:PRK06460 22 PIYQTTAYHYPEGE----KYR-------YSREANPTVLELTKKIVELENAEMGVAFSSGMGAISTTALALLKPGNSVLVH 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 111 RAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 190
Cdd:PRK06460 91 RDMFGRSYRFFTDYLKNWGVNVDASNPGSDNIIEKAKSKRYDVVFVENITNPLLRVVDITELSKVCKENGSILIVDATFS 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 191 TPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFGVVRTLGPSMSPFNAWVFLKGLETLRLRMKAHCES 270
Cdd:PRK06460 171 TPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYGKLLNVIDQMRRTLGTSLDPHAAYLTLRGIKTLKIRMDVINRN 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 271 AQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPA 350
Cdd:PRK06460 251 AEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVNGGQESALKVMKSLKLIIPAQTLGGVNSVISHPA 330
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 908704900 351 TTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK06460 331 TMSHRTLSLEERKIVGITDSLLRLSVGIEDVNDLIEDLDRAL 372
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
8-392 |
1.47e-97 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 295.07 E-value: 1.47e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 8 EYQLDTLAIRTGHtRSFE--GEHGEPIFLTSSFVYENAeeaaakfsGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVA 85
Cdd:PRK08247 2 MSTIETKLAQIGN-RSDErtGTVNPPVYFSTAYRHEGI--------GESTGFDYSRTGNPTRGVLEQAIADLEGGDQGFA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 86 TSSGMGAILSVtMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAE 165
Cdd:PRK08247 73 CSSGMAAIQLV-MSLFRSGDELIVSSDLYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQ 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 166 IADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQ-LLEEVFGVVRTLGPS 244
Cdd:PRK08247 152 ETDIAAIAKIAKKHGLLLIVDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQeLCERLAYYQNAAGAV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 245 MSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLpaheghelaakqqtgfGGIVSFVVKGEregAW 324
Cdd:PRK08247 232 LSPFDSWLLIRGMKTLALRMRQHEENAKAIAAFLNEQPGVTDVLYPGR----------------GGMLSFRLQDE---EW 292
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 325 --KVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK08247 293 vnPFLKSLKLITFAESLGGVESFITYPATQTHADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQAF 362
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
13-392 |
1.75e-96 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 293.82 E-value: 1.75e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 13 TLAIRTGHTRsfEGEHGE---PIFLTSSFVYEnaeeaaaKFSGQVQGNiYSRFTNPTVSMFEKRLAALDGAERAVATSSG 89
Cdd:PRK08776 15 TAAVRAGIDR--DTAYGAvtpPIVLSSNFSFD-------GFGNKRQYD-YTRSGNPTRDLLGEALAELEGGAGGVITATG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 90 MGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADI 169
Cdd:PRK08776 85 MGAINLVLNALLQPGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNPLLRITDL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 170 QALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVG-NHQLLEEVFGVVRTLGPSMSPF 248
Cdd:PRK08776 165 RFVIEAAHKVGALTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVArDAELHQQLVWWANALGLTGSPF 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 249 NAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWKVID 328
Cdd:PRK08776 245 DAFLTLRGLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFELEGGEAAVRAFVD 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 908704900 329 NTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK08776 325 GLRYFTLAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRAGL 388
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
59-395 |
2.59e-96 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 292.83 E-value: 2.59e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 59 YSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAIlSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLC 138
Cdd:PRK08064 48 YSRSGNPTREALEDIIAELEGGTKGFAFASGMAAI-STAFLLLSKGDHVLISEDVYGGTYRMITEVLSRFGIEHTFVDMT 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 139 DLDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGR 218
Cdd:PRK08064 127 NLEEVAQNIKPNTKLFYVETPSNPLLKVTDIRGVVKLAKAIGCLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAGHSD 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 219 ALGG-AVVGNHQLLEEVFGVVRTLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEG 297
Cdd:PRK08064 207 VLAGlAVVKDEELAQKLYFLQNSFGAVLGVQDCWLVLRGLKTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQTHLG 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 298 HELAAKQQTGFGGIVSFVVKGErEGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVG 377
Cdd:PRK08064 287 FDIQQSQATSAGAVLSFTLQSE-EAVRQFVSHVKLPVFAVSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVG 365
|
330
....*....|....*...
gi 908704900 378 LEDINDIIRDISRGLDLI 395
Cdd:PRK08064 366 LENVDDLIADFEQALSYV 383
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
31-392 |
1.58e-95 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 290.65 E-value: 1.58e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 31 PIFLTSSFvYENAeeaaakfSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSVtMAYLKAGDHVICS 110
Cdd:PRK06176 24 PIYQTSTY-RQDA-------IGRPKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHAV-FSLFQSGDHVLLG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 111 RAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 190
Cdd:PRK06176 95 DDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKDHGLLTIVDNTFA 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 191 TPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNH-QLLEEVFGVVRTLGPSMSPFNAWVFLKGLETLRLRMKAHCE 269
Cdd:PRK06176 175 TPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNeALAQEIAFFQNAIGGVLGPQDSWLLQRGIKTLGLRMEAHQK 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 270 SAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREgAWKVIDNTKFISITGNLGDVKSTITHP 349
Cdd:PRK06176 255 NALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSE-AVAFVESLKLFILGESLGGVESLVGIP 333
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 908704900 350 ATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK06176 334 AFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAF 376
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
31-392 |
2.99e-95 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 292.70 E-value: 2.99e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 31 PIFLTSSFVYENAEEaaakfSGQVQgniYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSVTMaYLKAGDHVICS 110
Cdd:PLN02509 107 PLYQTATFKQPSAIE-----NGPYD---YTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTH-LIKNGEEIVAG 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 111 RAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 190
Cdd:PLN02509 178 DDVYGGSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIAEMAHAQGALVLVDNSIM 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 191 TPVLQQPLKFGADLVIYSATKYLDGQGRALGGAV-VGNHQLLEEVFGVVRTLGPSMSPFNAWVFLKGLETLRLRMKAHCE 269
Cdd:PLN02509 258 SPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLaVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQE 337
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 270 SAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVkGEREGAWKVIDNTKFISITGNLGDVKSTITHP 349
Cdd:PLN02509 338 NARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFIT-GSVALSKHLVETTKYFSIAVSFGSVKSLISMP 416
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 908704900 350 ATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PLN02509 417 CFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
11-392 |
1.25e-93 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 285.57 E-value: 1.25e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 11 LDTLAIRTGHTRSFEGEHGEPIFLTSSFVYENAEEaaakfSGQVQgniYSRFTNPTVSMFEKRLAALDGAERAVATSSGM 90
Cdd:TIGR01329 1 LSTLLVNTDNKNDPYDASSMPIYQTATFKQPLAIE-----NGPYD---YTRSGNPTRTALESLLAKLDKADRAFAFSSGM 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 91 GAiLSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQ 170
Cdd:TIGR01329 73 AA-LDVITRLLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 171 ALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAV-VGNHQLLEEVFGVVRTLGPSMSPFN 249
Cdd:TIGR01329 152 KISEMAHAQNALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLaVKGEEIAKKVYFLQNSTGSGLAPFD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 250 AWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVkGEREGAWKVIDN 329
Cdd:TIGR01329 232 CWLLLRGIKTLAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKGAGSVLSFET-GSVALSKRLVEA 310
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 908704900 330 TKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:TIGR01329 311 TKLFSITVSFGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAF 373
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
27-395 |
6.12e-93 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 284.27 E-value: 6.12e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 27 EHG---EPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSVTMAYLKA 103
Cdd:PRK05939 6 EHGavhKPIHTSVTYGYEDARDLIDVFQGKKPGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVFLTLLRA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 104 GDHVICSRAVFGSVVALFEKyIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALL 183
Cdd:PRK05939 86 GDHLVSSQFLFGNTNSLFGT-LRGLGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERGLLY 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 184 AVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVV--------GNHQLLEEV-------FGV-------VRTL 241
Cdd:PRK05939 165 VVDNTMTSPWLFRPKDVGASLVINSLSKYIAGHGNALGGAVTdtglfdwsAYPNIFPAYrkgdpqqWGLtqirkkgLRDM 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 242 GPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKgERE 321
Cdd:PRK05939 245 GATLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLSFELA-DGI 323
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 908704900 322 GAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLDLI 395
Cdd:PRK05939 324 DCFDFLNRLKLVIKATHLGDTRTLVIPVAPTIYYEMGAERRASMGIADSLIRVSVGIEDEADLIADFEQALDAT 397
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
25-393 |
7.20e-92 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 282.72 E-value: 7.20e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 25 EGEHGEPIFLTSSFVYENAEEAAAKF----------SGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAIL 94
Cdd:PRK07049 33 EGAVKPPVFLTSTFVFRSAEDGRDFFdyvsgrkeppAGEGAGLVYSRFNHPNSEIVEDRLAVYEGAESAALFSSGMSAIA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 95 SVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVD-ITFVDLCDLDDWKNAV-----RPETKLLFVESPSNPLAEIAD 168
Cdd:PRK07049 113 TTLLAFVRPGDVILHSQPLYGGTETLLAKTFRNFGVGaVGFADGLSEAAIGAAAeaaaaKGRVSLILIETPANPTNSLVD 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 169 IQALADIAHANGA------LLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFGVVRTLG 242
Cdd:PRK07049 193 VAAVRRVADAIEArqghrpIIACDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAGAVLGRKALIRQVRALRSAIG 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 243 PSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYagLPAHEGHELAAK----QQTGFGGIVSFVVKG 318
Cdd:PRK07049 273 TQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHY--LPFLDPDSAYGAvykrQCTGAGSTFSFDIKG 350
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 908704900 319 EREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:PRK07049 351 GQAAAFRFLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHPDDLIADLAQALD 425
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
13-392 |
9.30e-90 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 276.01 E-value: 9.30e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 13 TLAIRTGHTRsfEGEHG---EPIFLTSSFvyenaeeaaaKFSG--QVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATS 87
Cdd:PRK08045 7 TIAVRSGLND--DEQYGcvvPPIHLSSTY----------NFTGfnEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTN 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 88 SGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIA 167
Cdd:PRK08045 75 TGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 168 DIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVG-NHQLLEEVFGVVRTLGPSMS 246
Cdd:PRK08045 155 DIAKICHLAREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAkDPDVVTELAWWANNIGVTGG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 247 PFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWKV 326
Cdd:PRK08045 235 AFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRF 314
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 908704900 327 IDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK08045 315 LGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGF 380
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
1-392 |
1.01e-87 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 270.80 E-value: 1.01e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 1 MNQSDDLeyqLDTLAIRTGHTRSFEGEHG-EPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDG 79
Cdd:PRK05968 1 MNDGLDP---FDLAALITAHDEGNAFDAVvPPIFQTSLFTFDSYDEMEDVYAGEKVRPIYSRGDNPTVRAFEEMLAKLEG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 80 AERAVATSSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVrPETKLLFVESP 159
Cdd:PRK05968 78 AEDARGFASGMAAISSTVLSFVEPGDRIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEAVAKAL-PGAKLLYLESP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 160 SNPLAEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFGVVR 239
Cdd:PRK05968 157 TSWVFELQDVAALAALAKRHGVVTMIDNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVVAGSKEHIARINAEAY 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 240 T-LGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELaakqqTGFGGIVSFVVKG 318
Cdd:PRK05968 237 PyLGAKLSPFEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHPPAGL-----SGTSGLFSFIFRE 311
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 908704900 319 EREGAwKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK05968 312 GIDVR-AFADALKLFRLGVSWGGHESLVVPAEVVLQQKAQPNSAARFGVSPRSVRLHVGLEGTEALWADLEQAL 384
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
8-390 |
1.47e-85 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 265.22 E-value: 1.47e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 8 EYQLDTLAIRTG-HTRSFEGEHGEPIFLTSSFVYenaeeaaAKFsGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVAT 86
Cdd:PRK08861 3 TRKPATIAVRTGiESDSQYHAVVPPIYLSTNYGF-------PAF-GEVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 87 SSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEI 166
Cdd:PRK08861 75 NCGTSALNLWVSALLGPDDLIVAPHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 167 ADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNH-QLLEEVFGVVRTLGPSM 245
Cdd:PRK08861 155 VDIAELCQKAKAVGALVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTkEHAEELAWWGNCIGATG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 246 SPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREGAWK 325
Cdd:PRK08861 235 TPFDSYMTLRGIRTLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFAGSFEQLKV 314
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 908704900 326 VIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISR 390
Cdd:PRK08861 315 FVKALALFSLAESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLIADLDQ 379
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
11-393 |
1.36e-83 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 260.22 E-value: 1.36e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 11 LDTLAIRTGHTRSFE-GEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSG 89
Cdd:PRK06434 9 FNTRAVQSGELRDPRfGNVTTPIFETSTFVYPNSEKEAYMDSTRGMPYIYTRWGNPTVQAFEEKYAVLENAEHALSFSSG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 90 MGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLD--DWKNAvrpETKLLFVESPSNPLAEIA 167
Cdd:PRK06434 89 MGAITSAILSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDTDRLNslDFDPS---NYDLIYAESITNPTLKVP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 168 DIQALADIAHANgaLLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAV-VGNHQLLEEVFGVVRTLGPSMS 246
Cdd:PRK06434 166 DIKNVSSFCHEN--DVIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAgTNNKSIFNNLVERRKTLGSNPD 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 247 PFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLpaheghELAAKQQTGFGGIVSFVVKGEREgAWKV 326
Cdd:PRK06434 244 PIQAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPDT------EIGKKVLRGFGGMLSFELRSMED-VHKF 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 908704900 327 IDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:PRK06434 317 IRNLEIPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENALS 383
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
13-392 |
6.65e-79 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 249.59 E-value: 6.65e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 13 TLAIRTGHTRSFEGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGA 92
Cdd:PRK06702 9 TICVQGGYTPKNGEPRVLPLYQSTTYKYDTSDDLAALFNLEAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASGQAA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 93 ILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDL-CDLDDWKNAVRPETKLLFVESPSNPLAEIADIQA 171
Cdd:PRK06702 89 IMLAVLNICSSGDHLLCSSTVYGGTFNLFGVSLRKLGIDVTFFNPnLTADEIVALANDKTKLVYAESLGNPAMNVLNFKE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 172 LADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVV--GNH--------QLLE--------- 232
Cdd:PRK06702 169 FSDAAKELEVPFIVDNTLATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdgGNFdwtngkypELVEpdpsyhgvs 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 233 --EVFG-----------VVRTLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHE 299
Cdd:PRK06702 249 yvQNFGaaayivkarvqLLRDYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDSNENYS 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 300 LAAKQ-QTGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGL 378
Cdd:PRK06702 329 LAQKYlKKGASGVLTFGIKGGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIRLSVGI 408
|
410
....*....|....
gi 908704900 379 EDINDIIRDISRGL 392
Cdd:PRK06702 409 EDVSDIIADLEAAL 422
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
17-393 |
3.28e-77 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 242.98 E-value: 3.28e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 17 RTGHTRSFEGEHGEPIFLTSSFvyenaeeaAAKF---SGQVQG-NIYSRFTNPTVSMFEKRLAALDGAErAVATSSGMGA 92
Cdd:PRK07582 7 RSVHAGGPEAVPGEPVLPGPVF--------AAPYhlsPGEPTGpDTYGRASNPTWRALEAALGELEGAE-ALVFPSGMAA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 93 ILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDitfVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQAL 172
Cdd:PRK07582 78 ITAVLRALLRPGDTVVVPADGYYQVRALAREYLAPLGVT---VREAPTAGMAEAALAGADLVLAETPSNPGLDVCDLAAL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 173 ADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNH-QLLEEVFGVVRTLGPSMSPFNAW 251
Cdd:PRK07582 155 AAAAHAAGALLVVDNTTATPLGQRPLELGADLVVASDTKALTGHSDLLLGYVAGRDpELMAAVERWRLLAGAIPGPFEAW 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 252 VFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVkGEREGAWKVIDNTK 331
Cdd:PRK07582 235 LAHRSLGTLGLRFARQCANALAVAELLAGHPAVRGVRYPGLPGDPAHEVAARQMRRFGGLVSFEL-ADAAAAERFVAASR 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 908704900 332 FISITGNLGDVKSTithpattthgklsADAKAAAG--IQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:PRK07582 314 LVVAATSFGGVHTS-------------ADRRARWGdaVPEGFVRLSCGIEDTDDLVADLERALD 364
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
26-377 |
7.34e-77 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 243.90 E-value: 7.34e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 26 GEHG---EPIFLTSSFVYENAEEAAAKFSGQVQGN----IYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSVTM 98
Cdd:PLN02242 30 GEHGgvnMSIEASATFTVMEPDTMRRMFSGELGPDrdfyIYSRHFNPTVLNLGRQMAALEGTEAAYCTASGMSAISSVLL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 99 AYLKAGDHVICSRAVFGSVVALFEKYIA-KFGVDITFVDLCDLDDWKNAVRP-ETKLLFVESPSNPLAEIADIQALADIA 176
Cdd:PLN02242 110 QLCSSGGHVVASNTLYGGTHALLAHFLPrKCNITTTFVDITDLEAVKKAVVPgKTKVLYFESISNPTLTVADIPELARIA 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 177 HANGALLAVDNSFcTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVF----GVVRTLGPSMSPFNAWV 252
Cdd:PLN02242 190 HEKGVTVVVDNTF-APMVLSPARLGADVVVHSISKFISGGADIIAGAVCGPAELVNSMMdlhhGALMLLGPTMNPKVAFE 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 253 FLKGLETLRLRMKAHCESAQILAEWLSthEKVEKVYYAGLPAHEGHELAAKQQT---GFGGIVSFVVKGErEGAWKVIDN 329
Cdd:PLN02242 269 LSERLPHLSLRMKEHCRRAMEYAKRMK--ELGLKVIYPGLEDHPQHALLKSMANkgyGFGGLLCLDMDTE-ERANRLMRY 345
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 908704900 330 ----TKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVG 377
Cdd:PLN02242 346 lqnsTQFGFMAVSLGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVG 397
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
8-393 |
1.59e-69 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 223.16 E-value: 1.59e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 8 EYQLDTLAIRTG-HTRSFEGEHGEPIFLTSSfvYENAEeaaakfSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVAT 86
Cdd:PRK07269 4 DLHINTILAQAGiKSDEATGALVTPLHFSTT--YQHPE------FGQSTGFDYTRTKNPTRAKLEETLAAIESADYALAT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 87 SSGMGAILsVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDlcDLDDWKNAVRPETKLLFVESPSNPLAEI 166
Cdd:PRK07269 76 SSGMSAIV-LAFSVFPVGSKVVAVRDLYGGSFRWFNQQEKEGRFHFTYAN--TEEELIAAIEEDTDIVYIETPTNPLMVE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 167 ADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQ-LLEEVFGVVRTLGPSM 245
Cdd:PRK07269 153 FDIEKVAKLAHAKGAKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLAGVVVTNDLeLYEKLFYNLNTTGAVL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 246 SPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYaglpaheghelaakqqTGFGGIVSFVVKGEREGAwK 325
Cdd:PRK07269 233 SPFDSYLLMRGLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLY----------------TGKGGMISFKVADETRIP-H 295
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 908704900 326 VIDNTKFISITGNLGDVKSTITHPATTTHGKLSADAKAAAGIQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:PRK07269 296 ILNSLKVFTFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLKQALE 363
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
22-392 |
3.46e-61 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 202.35 E-value: 3.46e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 22 RSFEGEHGEPIFLTSSFVYENAEEAAAKfsgqVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSVTMAYL 101
Cdd:PRK05967 25 GDYHGFVNPPVVHASTVLFPDAETMATR----GQKYTYGTRGTPTTDALCKAIDALEGSAGTILVPSGLAAVTVPFLGFL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 102 KAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGA 181
Cdd:PRK05967 101 SPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQDIPAIAEAAHRHGA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 182 LLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFGVVRTLGPSMSPFNAWVFLKGLETLR 261
Cdd:PRK05967 181 IVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLGTVSANEKCWPQLLEAHGTLGLCAGPDDTYQILRGLRTMG 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 262 LRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGEREG----AWKVIDNTKFISITG 337
Cdd:PRK05967 261 IRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSGASGIFSFVLAAGPEKgkakAHAFLDALEIFGLGY 340
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 908704900 338 NLGDVKStithpaTTTHGKLSaDAKAAAGIQEG-LIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK05967 341 SWGGYES------LALHVKLG-DRTVAKAPYAGpVIRLQIGLEDVPDLKADLERGF 389
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
31-392 |
1.37e-51 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 177.22 E-value: 1.37e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 31 PIFLTSSFVYENAEEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSVTMAYLKAGDHVICS 110
Cdd:PRK07050 31 PVARASTVVFPDLATMRALDWRQDVQWRYGLHATPTSLALAQRLAEIEGGRHALLQPSGLAAISLVYFGLVKAGDDVLIP 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 111 RAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 190
Cdd:PRK07050 111 DNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTMEVPDVPAITAAARARGVVTAIDNTYS 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 191 TPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFGVVRT-LGPSMSPFNAWVFLKGLETLRLRMKAHCE 269
Cdd:PRK07050 191 AGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADAELHAKLKLARMrLGIGVSADDCSLVLRGLPSLQVRLAAHDR 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 270 SAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKgEREGAWKV---IDNTKFISITGNLGDVKS-T 345
Cdd:PRK07050 271 SALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLFSVVFD-ERYSPAQVdafVEALELFAIGWSWGGACSlA 349
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 908704900 346 ITHPATTTHGklsadakAAAGIQEGLIRVSVGLEDINDIIRDISRGL 392
Cdd:PRK07050 350 MPYDVASMRT-------AKWPHRGTLVRLYIGLEDEADLIADLEQAL 389
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
10-393 |
1.30e-50 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 174.54 E-value: 1.30e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 10 QLDTLAIRTGHTRSF-EGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNI-YSRFTNPTVSMFEKRLAALDGAERAVATS 87
Cdd:PRK09028 4 KKATKIVSAGRDKKWtKGVINPPVFRASTVVFDTVAEMRHAAKNRANGEMfYGRRGTPTHFAFQAAIVELEGGAGTALYP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 88 SGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAEIA 167
Cdd:PRK09028 84 SGAAAISNALLSFLKAGDHLLMVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITMEVQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 168 DIQALADIAHANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGNH----QLLEEVFgvvrTLGP 243
Cdd:PRK09028 164 DVPTLSRIAHEHDIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVMLGTATANEkhwdQLREHSY----LMGQ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 244 SMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVK-GEREG 322
Cdd:PRK09028 240 CTSPDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKqGDPKA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 908704900 323 AWKVIDNTKFISITGNLGDVKSTIThpATTTHGKLSADAKAAAgiQEGLIRVSVGLEDINDIIRDISRGLD 393
Cdd:PRK09028 320 VTALVEGMQHFKMGFSWGGFESLIL--GVFGINKLRTATNWDF--SKPLIRLHIGLEDVDDLIADLEAGFE 386
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
8-395 |
1.62e-43 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 156.02 E-value: 1.62e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 8 EYQLDTLAIRTGHTRSF-EGEHGEPIFLTSSFVYENAEEAAAKFSGQVQGNI-YSRFTNPTVSMFEKRLAALDGAERAVA 85
Cdd:PRK08114 3 DKKLDTQLVNAGRSKKYtQGSVNSVIQRASSLVFDSVEAKKHATRNRANGELfYGRRGTLTHFSLQEAMCELEGGAGCAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 86 TSSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLDDWKNAVRPETKLLFVESPSNPLAE 165
Cdd:PRK08114 83 YPCGAAAVANAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGSITME 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 166 IADIQALADIAH--ANGALLAVDNSFCTPVLQQPLKFGADLVIYSATKYLDGQGRALGGAVVGN----HQLLEEVFgvvr 239
Cdd:PRK08114 163 VHDVPAIVAAVRsvNPDAVIMIDNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIGTAVANarcwEQLRENSY---- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 240 TLGPSMSPFNAWVFLKGLETLRLRMKAHCESAQILAEWLSTHEKVEKVYYAGLPAHEGHELAAKQQTGFGGIVSFVVKGE 319
Cdd:PRK08114 239 LMGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKKK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 320 --REGAWKVIDNTKFISITGNLGDVKSTITHpattTHGKLSADAKAAAGIQ-EG-LIRVSVGLEDINDIIRDISRGLDLI 395
Cdd:PRK08114 319 ltDEQLANYLDNFSLFSMAYSWGGFESLILA----NQPEEIAAIRPAGEVDfTGtLIRLHIGLEDVDDLIADLAAGFARI 394
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
70-312 |
4.66e-14 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 72.76 E-value: 4.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 70 FEKRLAALDGAERAVATSSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFEKY---IAKFGVDITFVDLCDLDDWKNA 146
Cdd:cd00609 49 LGRRGGVDVPPEEIVVTNGAQEALSLLLRALLNPGDEVLVPDPTYPGYEAAARLAgaeVVPVPLDEEGGFLLDLELLEAA 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 147 VRPETKLLFVESPSNP---LAEIADIQALADIAHANGALLAVD--------NSFCTPVLQQPLKFGADLVIYSATKYLDG 215
Cdd:cd00609 129 KTPKTKLLYLNNPNNPtgaVLSEEELEELAELAKKHGILIISDeayaelvyDGEPPPALALLDAYERVIVLRSFSKTFGL 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 216 QG-RaLGGAVVGNHQLLEEVFGVVRTLGPSMSPFNAWVFLKGLET----LRLRMKAHCESAQILAEWLSTHEKVEKVY-- 288
Cdd:cd00609 209 PGlR-IGYLIAPPEELLERLKKLLPYTTSGPSTLSQAAAAAALDDgeehLEELRERYRRRRDALLEALKELGPLVVVKps 287
|
250 260
....*....|....*....|....*....
gi 908704900 289 -----YAGLPAHEGHELAAKQQTGFGGIV 312
Cdd:cd00609 288 ggfflWLDLPEGDDEEFLERLLLEAGVVV 316
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
70-227 |
1.63e-12 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 65.10 E-value: 1.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 70 FEKRLAAL--DGAERAVATSSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALFekyIAKFGVDITFV----------DL 137
Cdd:cd01494 5 LEEKLARLlqPGNDKAVFVPSGTGANEAALLALLGPGDEVIVDANGHGSRYWVA---AELAGAKPVPVpvddagygglDV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 138 CDLDDWKNAvrPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC---TPVLQQPLKFG-ADLVIYSATKYL 213
Cdd:cd01494 82 AILEELKAK--PNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAggaSPAPGVLIPEGgADVVTFSLHKNL 159
|
170
....*....|....
gi 908704900 214 DGQGralGGAVVGN 227
Cdd:cd01494 160 GGEG---GGVVIVK 170
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
29-186 |
4.68e-10 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 60.40 E-value: 4.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 29 GEPIFLTSsfvyENAEEAAAKFSGQVQGNIYSRFTNPTVsmFEKRLAAL--------DGAERAVATSSGMGAILSV-TMA 99
Cdd:pfam00155 9 NEYLGDTL----PAVAKAEKDALAGGTRNLYGPTDGHPE--LREALAKFlgrspvlkLDREAAVVFGSGAGANIEAlIFL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 100 YLKAGDHVICSRAVFGSVVALFEKYiakfGVDITFVDL-------CDLDDWKNAVRPETKLLFVESPSNP---LAEIADI 169
Cdd:pfam00155 83 LANPGDAILVPAPTYASYIRIARLA----GGEVVRYPLydsndfhLDFDALEAALKEKPKVVLHTSPHNPtgtVATLEEL 158
|
170
....*....|....*..
gi 908704900 170 QALADIAHANGALLAVD 186
Cdd:pfam00155 159 EKLLDLAKEHNILLLVD 175
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
80-187 |
2.21e-09 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 58.60 E-value: 2.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 80 AERAVATSSGMGAILSVTMAYLKAGDHVICSR---AVFGSVVALFekyiakfGVDITFVDLC-------DLDDWKNAVRP 149
Cdd:COG0436 90 PDEILVTNGAKEALALALLALLNPGDEVLVPDpgyPSYRAAVRLA-------GGKPVPVPLDeengflpDPEALEAAITP 162
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 908704900 150 ETKLLFVESPSNP---LAEIADIQALADIAHANGALLAVDN 187
Cdd:COG0436 163 RTKAIVLNSPNNPtgaVYSREELEALAELAREHDLLVISDE 203
|
|
| PLN02855 |
PLN02855 |
Bifunctional selenocysteine lyase/cysteine desulfurase |
72-248 |
2.94e-09 |
|
Bifunctional selenocysteine lyase/cysteine desulfurase
Pssm-ID: 215460 [Multi-domain] Cd Length: 424 Bit Score: 58.22 E-value: 2.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 72 KRLAALDGAERA---VATSSGMGAILSVT----MAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLC-----D 139
Cdd:PLN02855 83 KKVAAFINASTSreiVFTRNATEAINLVAytwgLANLKPGDEVILSVAEHHSNIVPWQLVAQKTGAVLKFVGLTpdevlD 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 140 LDDWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNsfCTPVLQQPL---KFGADLVIYSATKYLDGQ 216
Cdd:PLN02855 163 VEQLKELLSEKTKLVATHHVSNVLGSILPVEDIVHWAHAVGAKVLVDA--CQSVPHMPVdvqTLGADFLVASSHKMCGPT 240
|
170 180 190
....*....|....*....|....*....|..
gi 908704900 217 GRalgGAVVGNHQLLEevfgvvrtlgpSMSPF 248
Cdd:PLN02855 241 GI---GFLWGKSDLLE-----------SMPPF 258
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
15-318 |
3.15e-08 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 54.95 E-value: 3.15e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 15 AIRTGHTRSFEgehgepifltSSFVYENAEEAAAKFsgqvqgniysrftnptvsmfekrLAAlDGAERAVATSSGMGAIL 94
Cdd:pfam00266 30 VHRGVHTLGKE----------ATQAYEEAREKVAEF-----------------------INA-PSNDEIIFTSGTTEAIN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 95 SVTMAY---LKAGDHVICSRAVFGSVVALFEKyIAKF-GVDITFVDL-----CDLDDWKNAVRPETKLLFVESPSNPLAE 165
Cdd:pfam00266 76 LVALSLgrsLKPGDEIVITEMEHHANLVPWQE-LAKRtGARVRVLPLdedglLDLDELEKLITPKTKLVAITHVSNVTGT 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 166 IADIQALADIAHANGALLAVDnsFCTPVLQQPL---KFGADLVIYSATKYLdgqGRALGGAVVGNHQLLEEV----FG-- 236
Cdd:pfam00266 155 IQPVPEIGKLAHQYGALVLVD--AAQAIGHRPIdvqKLGVDFLAFSGHKLY---GPTGIGVLYGRRDLLEKMppllGGgg 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 237 ---VV----RTLGPSMSPFNA-------WVFL-KGLETL-RLRMKAHCESAQILAEWLsthekvekvyYAGLPAHEGHEL 300
Cdd:pfam00266 230 mieTVslqeSTFADAPWKFEAgtpniagIIGLgAALEYLsEIGLEAIEKHEHELAQYL----------YERLLSLPGIRL 299
|
330
....*....|....*...
gi 908704900 301 AAKQQTgfGGIVSFVVKG 318
Cdd:pfam00266 300 YGPERR--ASIISFNFKG 315
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
102-233 |
6.54e-08 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 54.01 E-value: 6.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 102 KAGDHVICSRAVFGSVV----ALFEKYiakfGVDITFVDL-----CDLDDWKNAVRPETKLLFVESPSNPLAEIADIQAL 172
Cdd:cd06453 86 KPGDEIVTSVMEHHSNIvpwqQLAERT----GAKLKVVPVdddgqLDLEALEKLLTERTKLVAVTHVSNVLGTINPVKEI 161
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 908704900 173 ADIAHANGALLAVDNSFCTPVLqqPL---KFGADLVIYSATKYLDGQGralGGAVVGNHQLLEE 233
Cdd:cd06453 162 GEIAHEAGVPVLVDGAQSAGHM--PVdvqDLGCDFLAFSGHKMLGPTG---IGVLYGKEELLEE 220
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
63-233 |
1.04e-07 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 53.44 E-value: 1.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 63 TNPTVSMFEKRLAALDGAERAVATSSGMGAILSVTMAY-LKAGDHVICSRAVFGSVV--ALFEKYIAKFgVDITFVDLC- 138
Cdd:pfam01041 22 TGPYVREFERAFAAYLGVKHAIAVSSGTAALHLALRALgVGPGDEVITPSFTFVATAnaALRLGAKPVF-VDIDPDTYNi 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 139 DLDDWKNAVRPETKLLFvesPSNPLAEIADIQALADIAHANGALLAVD--NSFCTPVLQQPLKFGADLVIYS--ATKYLD 214
Cdd:pfam01041 101 DPEAIEAAITPRTKAII---PVHLYGQPADMDAIRAIAARHGLPVIEDaaHALGATYQGKKVGTLGDAATFSfhPTKNLT 177
|
170 180
....*....|....*....|
gi 908704900 215 -GQgralGGAVVGNHQLLEE 233
Cdd:pfam01041 178 tGE----GGAVVTNDPELAE 193
|
|
| PRK00451 |
PRK00451 |
aminomethyl-transferring glycine dehydrogenase subunit GcvPA; |
96-221 |
1.22e-07 |
|
aminomethyl-transferring glycine dehydrogenase subunit GcvPA;
Pssm-ID: 234769 [Multi-domain] Cd Length: 447 Bit Score: 53.22 E-value: 1.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 96 VTMAY-LKAGDHVICSRAV---FGSVValfEKYIAKFGVDITFVDL----CDLDDWKNAVRPETKLLFVESPsNPLAEIA 167
Cdd:PRK00451 145 ALMAVrITKRKKVLVSGAVhpeYREVL---KTYLKGQGIEVVEVPYedgvTDLEALEAAVDDDTAAVVVQYP-NFFGVIE 220
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 908704900 168 DIQALADIAHANGALLAVdnsFCTPV----LQQPLKFGADLVIysatkyldGQGRALG 221
Cdd:PRK00451 221 DLEEIAEIAHAGGALFIV---GVDPVslglLKPPGEYGADIVV--------GEGQPLG 267
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
72-186 |
1.47e-07 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 52.83 E-value: 1.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 72 KRLAALDGAERA---VATSSGMGAILSV--TMAYLKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLC-----DLD 141
Cdd:COG0520 66 EKVARFIGAASPdeiIFTRGTTEAINLVayGLGRLKPGDEILITEMEHHSNIVPWQELAERTGAEVRVIPLDedgelDLE 145
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 908704900 142 DWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVD 186
Cdd:COG0520 146 ALEALLTPRTKLVAVTHVSNVTGTVNPVKEIAALAHAHGALVLVD 190
|
|
| GcvP1 |
COG0403 |
Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport ... |
77-206 |
1.64e-07 |
|
Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain is part of the Pathway/BioSystem: Glycine cleavage
Pssm-ID: 440172 [Multi-domain] Cd Length: 442 Bit Score: 53.11 E-value: 1.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 77 LDGAErAVATSsgmgailsVTMAY--LKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVD----LCDLDDWKNAVRPE 150
Cdd:COG0403 135 YDGAT-AAAEA--------MLMARrvTKRSNKVLVSEDVHPQTRAVLKTYAEPLGIEVVEVPdedgVTDLEALKALLDDD 205
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 151 TKLLFVESPsNPLAEIADIQALADIAHANGALLAVdnsFCTP----VLQQPLKFGADLVI 206
Cdd:COG0403 206 VAGVLVQYP-NFFGVIEDLRAIAEAAHAAGALVIV---AADPlslgLLKPPGELGADIVV 261
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
77-245 |
6.26e-07 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 50.91 E-value: 6.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 77 LDGAErAVATSSGMGAILSVTMAYLKAGDHVICSRAVFgSVVALFEKyiaKFGVDITFVDL----CDL----DDWKNAVR 148
Cdd:PRK06225 81 LDDDE-ALITAGATESLYLVMRAFLSPGDNAVTPDPGY-LIIDNFAS---RFGAEVIEVPIyseeCNYkltpELVKENMD 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 149 PETKLLFVESPSNPLA---EIADIQALADIAHANGALLAVDNSFCTPVLQQPLKFGAD----LVIYSATKYLDGQGRALg 221
Cdd:PRK06225 156 ENTRLIYLIDPLNPLGssyTEEEIKEFAEIARDNDAFLLHDCTYRDFAREHTLAAEYApehtVTSYSFSKIFGMAGLRI- 234
|
170 180
....*....|....*....|....*
gi 908704900 222 GAVVGNHQLLEEVFG-VVRTLGPSM 245
Cdd:PRK06225 235 GAVVATPDLIEVVKSiVINDLGTNV 259
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
71-180 |
6.95e-07 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 50.71 E-value: 6.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 71 EKRLAALDGAERAVATSSGMGAI-LSVTMAyLKAGDHVICSRAVFGSVVALFEKYIAKF-GVDITFVD---LCDLDDWKN 145
Cdd:PRK06108 75 SRLHGVATPPERIAVTSSGVQALmLAAQAL-VGPGDEVVAVTPLWPNLVAAPKILGARVvCVPLDFGGggwTLDLDRLLA 153
|
90 100 110
....*....|....*....|....*....|....*...
gi 908704900 146 AVRPETKLLFVESPSNPL---AEIADIQALADIAHANG 180
Cdd:PRK06108 154 AITPRTRALFINSPNNPTgwtASRDDLRAILAHCRRHG 191
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
63-188 |
7.25e-06 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 47.54 E-value: 7.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 63 TNPTVSMFEKRLAALDGAERAVATSSGMGAI-LSVTMAYLKAGDHVICSR----AVFGSVVALfekyiakfGVDITFVDl 137
Cdd:cd00616 16 LGPKVREFEKAFAEYLGVKYAVAVSSGTAALhLALRALGIGPGDEVIVPSftfvATANAILLL--------GATPVFVD- 86
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 908704900 138 CDLDDW-------KNAVRPETKLLFvesPSNPLAEIADIQALADIAHANGALLAVDNS 188
Cdd:cd00616 87 IDPDTYnidpeliEAAITPRTKAII---PVHLYGNPADMDAIMAIAKRHGLPVIEDAA 141
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
61-183 |
9.92e-06 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 46.99 E-value: 9.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 61 RFTN-PTVSMFEKRLAALDGAERAVATSSGMGAILSVTMAY-LKAGDHVICS----RAVFGSVVAL-----Fekyiakfg 129
Cdd:COG0399 25 WLTLgPEVKEFEEEFAAYLGVKHAVAVSSGTAALHLALRALgIGPGDEVITPaftfVATANAILYVgatpvF-------- 96
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 908704900 130 VDITFVDLC-DLDDWKNAVRPETKLLFvesPSNPLAEIADIQALADIAHANGALL 183
Cdd:COG0399 97 VDIDPDTYNiDPEALEAAITPRTKAII---PVHLYGQPADMDAIMAIAKKHGLKV 148
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
80-186 |
2.37e-05 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 46.08 E-value: 2.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 80 AERAVATSSGMGAILSVTMAYLKAGDHVIcsrAVFGSVVALFEkyIAK-FGVDITFVD-------LCDLDDWKNAVRPET 151
Cdd:PRK07324 80 PENILQTNGATGANFLVLYALVEPGDHVI---SVYPTYQQLYD--IPEsLGAEVDYWQlkeengwLPDLDELRRLVRPNT 154
|
90 100 110
....*....|....*....|....*....|....*...
gi 908704900 152 KLLFVESPSNPLAEIAD---IQALADIAHANGALLAVD 186
Cdd:PRK07324 155 KLICINNANNPTGALMDrayLEEIVEIARSVDAYVLSD 192
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
80-186 |
2.98e-05 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 45.89 E-value: 2.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 80 AERAVATSSGMGAILSVTMAYLKAGDHVICSRAVFGS---VVALFEkyiakfGVDItFVDLC-------DLDDWKNAVRP 149
Cdd:PRK05764 91 PSQVIVTTGAKQALYNAFMALLDPGDEVIIPAPYWVSypeMVKLAG------GVPV-FVPTGeengfklTVEQLEAAITP 163
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 908704900 150 ETKLLFVESPSNPLAEI---ADIQALADIAHANGALLAVD 186
Cdd:PRK05764 164 KTKALILNSPSNPTGAVyspEELEAIADVAVEHDIWVLSD 203
|
|
| GDC-P |
cd00613 |
Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine ... |
96-211 |
6.35e-05 |
|
Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1.2.10 (GDC) also annotated as glycine cleavage system or glycine synthase. GDC consists of four proteins P, H, L and T. The reaction catalysed by this protein is: Glycine + lipoylprotein <=> S-aminomethyldihydrolipoylprotein + CO2. Alpha-beta-type dimers associate to form an alpha(2)beta(2) tetramer, where the alpha- and beta-subunits are structurally similar and appear to have arisen by gene duplication and subsequent divergence with a loss of one active site. The members of this CD are widely dispersed among all three forms of cellular life.
Pssm-ID: 99737 [Multi-domain] Cd Length: 398 Bit Score: 44.91 E-value: 6.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 96 VTMAYLKAGDH---VICSRAVFGSVVALFEKYIAKFGVDITFVDLC-----DLDDWKNAVRPETKLLFVESPsNPLAEIA 167
Cdd:cd00613 97 AGLAAIRAYHKrnkVLVPDSAHPTNPAVARTRGEPLGIEVVEVPSDeggtvDLEALKEEVSEEVAALMVQYP-NTLGVFE 175
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 908704900 168 D-IQALADIAHANGALL--AVDNSFCTpVLQQPLKFGADLVIYSATK 211
Cdd:cd00613 176 DlIKEIADIAHSAGALVyvDGDNLNLT-GLKPPGEYGADIVVGNLQK 221
|
|
| PLN02651 |
PLN02651 |
cysteine desulfurase |
72-176 |
9.51e-05 |
|
cysteine desulfurase
Pssm-ID: 178257 [Multi-domain] Cd Length: 364 Bit Score: 44.26 E-value: 9.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 72 KRLAALDGAERA------VATSSGMGAILSVTMAYLKAGDHVICS----RAVFGSVVALFEKyiakfGVDITFV-----D 136
Cdd:PLN02651 50 AQVAALIGADPKeiiftsGATESNNLAIKGVMHFYKDKKKHVITTqtehKCVLDSCRHLQQE-----GFEVTYLpvksdG 124
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 908704900 137 LCDLDDWKNAVRPETKLLFVESPSNplaEIADIQALADIA 176
Cdd:PLN02651 125 LVDLDELAAAIRPDTALVSVMAVNN---EIGVIQPVEEIG 161
|
|
| Beta_elim_lyase |
pfam01212 |
Beta-eliminating lyase; |
64-281 |
1.38e-04 |
|
Beta-eliminating lyase;
Pssm-ID: 426128 [Multi-domain] Cd Length: 288 Bit Score: 43.36 E-value: 1.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 64 NPTVSMFEKRLAALDGAERAVATSSGMGAILSVTMAYLKAGDHVICSR------------AVFGSVVALFEKyIAKFGvD 131
Cdd:pfam01212 31 DPTVNRLEDRVAELFGKEAALFVPSGTAANQLALMAHCQRGDEVICGEpahihfdetgghAELGGVQPRPLD-GDEAG-N 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 132 ITFVDLCD-LDDWKNAVRPETKLLFVESPSN-------PLAEIADIQAladIAHANGALLAVD------NSFCTPVLQQP 197
Cdd:pfam01212 109 MDLEDLEAaIREVGADIFPPTGLISLENTHNsaggqvvSLENLREIAA---LAREHGIPVHLDgarfanAAVALGVIVKE 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 198 LKFGADLVIYSATKyldGQGRALGGAVVGNHQLLEEVFGVVRTLGPSMS----PFNAWVFLKGLETLRLRmKAHcESAQI 273
Cdd:pfam01212 186 ITSYADSVTMCLSK---GLGAPVGSVLAGSDDFIAKAIRQRKYLGGGLRqagvLAAAGLRALEEGVARLA-RDH-ATARR 260
|
....*...
gi 908704900 274 LAEWLSTH 281
Cdd:pfam01212 261 LAEGLELL 268
|
|
| PRK05166 |
PRK05166 |
histidinol-phosphate transaminase; |
99-189 |
1.91e-04 |
|
histidinol-phosphate transaminase;
Pssm-ID: 179950 Cd Length: 371 Bit Score: 43.20 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 99 AYLKAGDHVICSRAVFGsvvaLFEKYIAKFGVDITFVDLC-----DLDDWKNAVRPETKLLFVESPSNPLAEIADIQALA 173
Cdd:PRK05166 107 AVLRPGDRVVTLYPSFP----LHEDYPTMMGARVERVTVTpdlgfDLDALCAAVARAPRMLMFSNPSNPVGSWLTADQLA 182
|
90
....*....|....*...
gi 908704900 174 DIAHANGA--LLAVDNSF 189
Cdd:PRK05166 183 RVLDATPPetLIVVDEAY 200
|
|
| GDC-P |
pfam02347 |
Glycine cleavage system P-protein; This family consists of Glycine cleavage system P-proteins ... |
84-212 |
4.16e-04 |
|
Glycine cleavage system P-protein; This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1.2.10 (GDC) also annotated as glycine cleavage system or glycine synthase. GDC consists of four proteins P, H, L and T. The reaction catalyzed by this protein is:- Glycine + lipoylprotein <=> S-aminomethyldihydrolipoylprotein + CO2
Pssm-ID: 396772 [Multi-domain] Cd Length: 428 Bit Score: 42.36 E-value: 4.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 84 VATSS----GMGAILSVTMAY---LKAGDHVICSRAVFGSVVALFEKYIAKFGVDITFVDLCDLddwKNAVRPETKLLFV 156
Cdd:pfam02347 127 IANASlldeGTAAAEAMALAArasKKKGKKFVVDKDVHPQTLEVLKTRAKPFGIEIVEVDYTEE---GVTDLKDVFGVLV 203
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 157 ESPsNPLAEIADIQALADIAHANGALLAVdnsFCTP----VLQQPLKFGADLVIYSATKY 212
Cdd:pfam02347 204 QYP-NTDGRIEDYKELIELAHQRKSLVVV---AADLlaltLLKPPGEFGADIAVGSAQRF 259
|
|
| Orn_deC_like |
cd00615 |
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
71-266 |
9.45e-04 |
|
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.
Pssm-ID: 99739 [Multi-domain] Cd Length: 294 Bit Score: 40.69 E-value: 9.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 71 EKRLAALDGAERA-VATSSGMGAILSVTMAYLKAGDHVICSRAVFGSVVALF------EKYI-----AKFGVdITFVDLC 138
Cdd:cd00615 65 QELAARAFGAKHTfFLVNGTSSSNKAVILAVCGPGDKILIDRNCHKSVINGLvlsgavPVYLkpernPYYGI-AGGIPPE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 139 DLDDwKNAVRPETKLLFVESPsNPLAEIADIQALADIAHANGALLAVDNS----FC-TPVLQ-QPLKFGADLVIYSATKY 212
Cdd:cd00615 144 TFKK-ALIEHPDAKAAVITNP-TYYGICYNLRKIVEEAHHRGLPVLVDEAhgahFRfHPILPsSAAMAGADIVVQSTHKT 221
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 908704900 213 LDG--QGRAL---GGAVvgNHQLLEEVFGVVRTLGPS---MSPFNAWVFLKGLETLRLRMKA 266
Cdd:cd00615 222 LPAltQGSMIhvkGDLV--NPDRVNEALNLHQSTSPSyliLASLDVARAMMALEGKELVEEL 281
|
|
| SelA |
pfam03841 |
L-seryl-tRNA selenium transferase; |
68-234 |
9.93e-03 |
|
L-seryl-tRNA selenium transferase;
Pssm-ID: 309101 Cd Length: 367 Bit Score: 37.70 E-value: 9.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 68 SMFEKRLAALDGAERAVATSSGMGAILSVtMAYLKAGDHVICSRavfGSVVALFEKY-----IAKFGVDITFVDLCD--- 139
Cdd:pfam03841 50 AHIEELLCELTGAEDALVVNNNAAAVLLV-LNTLAAGKEVIISR---GELVEIGGSFripdvMKQAGVKLVEVGTTNrth 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 908704900 140 LDDWKNAVRPETKLLFVESPSN----------PLAEiadiqaLADIAHANGALLAVD--NSFCT----------PVLQQP 197
Cdd:pfam03841 126 LKDYEQAINENTALLMKVHTSNyriqgftkevELAE------LVELGHEKGLPVYEDlgSGSLVdlsqyglpkePTVQEL 199
|
170 180 190
....*....|....*....|....*....|....*...
gi 908704900 198 LKFGADLVIYSATKYLDG-QgralGGAVVGNHQLLEEV 234
Cdd:pfam03841 200 IAQGVDLVSFSGDKLLGGpQ----AGIIVGKKELIERI 233
|
|
| |
