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Conserved domains on  [gi|913695168|ref|WP_050450882|]
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multiubiquitin domain-containing protein [Burkholderia pseudomallei]

Protein Classification

Multi_ubiq domain-containing protein( domain architecture ID 10627973)

Multi_ubiq domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Multi_ubiq pfam14452
Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies ...
 16-73 1.71e-09

Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies in the same polypeptide. Members of this family are associated in gene neighborhoods, or on occasions fused to, bacterial homologs of components of ubiquitin-dependent modification system such as the E1, E2 and JAB metallopeptidase enzymes and a distinct metal-binding domain. The E2/UBC fold domain appears to be inactive. The JAB domain in these operons is usually fused to the E1 domain.


:

Pssm-ID: 433963  Cd Length: 69  Bit Score: 49.90  E-value: 1.71e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 913695168   16 TLNFRALEVPHDHPTGAQILEAAH-RAGPDALLLQRLPSGDLETIRLHEIPDLTA-SVEF 73
Cdd:pfam14452   4 IVNGRPFEVGDPTVTGAQIVALAGpDPPDDPVVLQTLGYGPDGEIRDGETVDLKApGVEF 63
Multi_ubiq super family cl16892
Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies ...
 82-111 4.76e-04

Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies in the same polypeptide. Members of this family are associated in gene neighborhoods, or on occasions fused to, bacterial homologs of components of ubiquitin-dependent modification system such as the E1, E2 and JAB metallopeptidase enzymes and a distinct metal-binding domain. The E2/UBC fold domain appears to be inactive. The JAB domain in these operons is usually fused to the E1 domain.


The actual alignment was detected with superfamily member pfam14452:

Pssm-ID: 433963  Cd Length: 69  Bit Score: 36.03  E-value: 4.76e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 913695168   82 YSLTVNDAQMEWAIRHISGATIRKLANLPE 111
Cdd:pfam14452   1 FTIIVNGRPFEVGDPTVTGAQIVALAGPDP 30
 
Name Accession Description Interval E-value
Multi_ubiq pfam14452
Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies ...
 16-73 1.71e-09

Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies in the same polypeptide. Members of this family are associated in gene neighborhoods, or on occasions fused to, bacterial homologs of components of ubiquitin-dependent modification system such as the E1, E2 and JAB metallopeptidase enzymes and a distinct metal-binding domain. The E2/UBC fold domain appears to be inactive. The JAB domain in these operons is usually fused to the E1 domain.


Pssm-ID: 433963  Cd Length: 69  Bit Score: 49.90  E-value: 1.71e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 913695168   16 TLNFRALEVPHDHPTGAQILEAAH-RAGPDALLLQRLPSGDLETIRLHEIPDLTA-SVEF 73
Cdd:pfam14452   4 IVNGRPFEVGDPTVTGAQIVALAGpDPPDDPVVLQTLGYGPDGEIRDGETVDLKApGVEF 63
Multi_ubiq pfam14452
Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies ...
 82-111 4.76e-04

Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies in the same polypeptide. Members of this family are associated in gene neighborhoods, or on occasions fused to, bacterial homologs of components of ubiquitin-dependent modification system such as the E1, E2 and JAB metallopeptidase enzymes and a distinct metal-binding domain. The E2/UBC fold domain appears to be inactive. The JAB domain in these operons is usually fused to the E1 domain.


Pssm-ID: 433963  Cd Length: 69  Bit Score: 36.03  E-value: 4.76e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 913695168   82 YSLTVNDAQMEWAIRHISGATIRKLANLPE 111
Cdd:pfam14452   1 FTIIVNGRPFEVGDPTVTGAQIVALAGPDP 30
 
Name Accession Description Interval E-value
Multi_ubiq pfam14452
Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies ...
 16-73 1.71e-09

Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies in the same polypeptide. Members of this family are associated in gene neighborhoods, or on occasions fused to, bacterial homologs of components of ubiquitin-dependent modification system such as the E1, E2 and JAB metallopeptidase enzymes and a distinct metal-binding domain. The E2/UBC fold domain appears to be inactive. The JAB domain in these operons is usually fused to the E1 domain.


Pssm-ID: 433963  Cd Length: 69  Bit Score: 49.90  E-value: 1.71e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 913695168   16 TLNFRALEVPHDHPTGAQILEAAH-RAGPDALLLQRLPSGDLETIRLHEIPDLTA-SVEF 73
Cdd:pfam14452   4 IVNGRPFEVGDPTVTGAQIVALAGpDPPDDPVVLQTLGYGPDGEIRDGETVDLKApGVEF 63
Multi_ubiq pfam14452
Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies ...
 82-111 4.76e-04

Multiubiquitin; A ubiquitin superfamily domain that is often present in multiple tandem copies in the same polypeptide. Members of this family are associated in gene neighborhoods, or on occasions fused to, bacterial homologs of components of ubiquitin-dependent modification system such as the E1, E2 and JAB metallopeptidase enzymes and a distinct metal-binding domain. The E2/UBC fold domain appears to be inactive. The JAB domain in these operons is usually fused to the E1 domain.


Pssm-ID: 433963  Cd Length: 69  Bit Score: 36.03  E-value: 4.76e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 913695168   82 YSLTVNDAQMEWAIRHISGATIRKLANLPE 111
Cdd:pfam14452   1 FTIIVNGRPFEVGDPTVTGAQIVALAGPDP 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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