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Conserved domains on  [gi|916333789|ref|WP_051068835|]
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YqaE/Pmp3 family membrane protein [Cesiribacter andamanensis]

Protein Classification

YqaE/Pmp3 family membrane protein( domain architecture ID 1694)

YqaE/Pmp3 family membrane protein similar to fungal plasma membrane proteolipid 3 and Escherichia coli UPF0057 membrane protein YqaE

Gene Ontology:  GO:0016020

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pmp3 super family cl00431
Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in ...
 1-50 6.32e-07

Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in the plasma membrane which, in S. pombe, is transcriptionally regulated by the Spc1 stress MAPK (mitogen-activated protein kinases) pathway. It functions to modulate the membrane potential, particularly to resist high cellular cation concentration. In eukaryotic organizms, stress-activated mitogen-activated protein kinases play crucial roles in transmitting environmental signals that will regulate gene expression for allowing the cell to adapt to cellular stress. Pmp3-like proteins are highly conserved in bacteria, yeast, nematode and plants.


The actual alignment was detected with superfamily member COG0401:

Pssm-ID: 469769  Cd Length: 53  Bit Score: 40.56  E-value: 6.32e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 916333789  1 MLLVIITILLPPLGVFLHQGeINAKFWISLLLTLLFYVPGLIYSLLVIFD 50
Cdd:COG0401   3 LLRIILAILLPPLGVFLTVG-LGKTFWINILLTLLGWIPGIIHALWVIAK 51
 
Name Accession Description Interval E-value
YqaE COG0401
Membrane potential modulator PMP3/YqaE, plasma membrane proteolipid 3 (PMP3)/Esi3/RCI2/UPF0057 ...
 1-50 6.32e-07

Membrane potential modulator PMP3/YqaE, plasma membrane proteolipid 3 (PMP3)/Esi3/RCI2/UPF0057 family [Energy production and conversion];


Pssm-ID: 440170  Cd Length: 53  Bit Score: 40.56  E-value: 6.32e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 916333789  1 MLLVIITILLPPLGVFLHQGeINAKFWISLLLTLLFYVPGLIYSLLVIFD 50
Cdd:COG0401   3 LLRIILAILLPPLGVFLTVG-LGKTFWINILLTLLGWIPGIIHALWVIAK 51
Pmp3 pfam01679
Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in ...
 2-49 3.45e-05

Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in the plasma membrane which, in S. pombe, is transcriptionally regulated by the Spc1 stress MAPK (mitogen-activated protein kinases) pathway. It functions to modulate the membrane potential, particularly to resist high cellular cation concentration. In eukaryotic organizms, stress-activated mitogen-activated protein kinases play crucial roles in transmitting environmental signals that will regulate gene expression for allowing the cell to adapt to cellular stress. Pmp3-like proteins are highly conserved in bacteria, yeast, nematode and plants.


Pssm-ID: 460290  Cd Length: 49  Bit Score: 36.22  E-value: 3.45e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 916333789   2 LLVIITILLPPLGVFLHQGeINAKFWISLLLTLLFYVPGLIYSLLVIF 49
Cdd:pfam01679  3 LLIILAIFLPPLAVFLKRG-CGKDFLINILLTLLGWIPGIIHALYIIY 49
 
Name Accession Description Interval E-value
YqaE COG0401
Membrane potential modulator PMP3/YqaE, plasma membrane proteolipid 3 (PMP3)/Esi3/RCI2/UPF0057 ...
 1-50 6.32e-07

Membrane potential modulator PMP3/YqaE, plasma membrane proteolipid 3 (PMP3)/Esi3/RCI2/UPF0057 family [Energy production and conversion];


Pssm-ID: 440170  Cd Length: 53  Bit Score: 40.56  E-value: 6.32e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 916333789  1 MLLVIITILLPPLGVFLHQGeINAKFWISLLLTLLFYVPGLIYSLLVIFD 50
Cdd:COG0401   3 LLRIILAILLPPLGVFLTVG-LGKTFWINILLTLLGWIPGIIHALWVIAK 51
Pmp3 pfam01679
Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in ...
 2-49 3.45e-05

Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in the plasma membrane which, in S. pombe, is transcriptionally regulated by the Spc1 stress MAPK (mitogen-activated protein kinases) pathway. It functions to modulate the membrane potential, particularly to resist high cellular cation concentration. In eukaryotic organizms, stress-activated mitogen-activated protein kinases play crucial roles in transmitting environmental signals that will regulate gene expression for allowing the cell to adapt to cellular stress. Pmp3-like proteins are highly conserved in bacteria, yeast, nematode and plants.


Pssm-ID: 460290  Cd Length: 49  Bit Score: 36.22  E-value: 3.45e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 916333789   2 LLVIITILLPPLGVFLHQGeINAKFWISLLLTLLFYVPGLIYSLLVIF 49
Cdd:pfam01679  3 LLIILAIFLPPLAVFLKRG-CGKDFLINILLTLLGWIPGIIHALYIIY 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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