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Conserved domains on  [gi|917536364|ref|WP_052142781|]
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MULTISPECIES: kinase [Burkholderia]

Protein Classification

PduX family protein( domain architecture ID 11468259)

PduX family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PduX COG4542
PduX protein involved in propanediol utilization and related proteins [Secondary metabolites ...
 9-290 4.24e-90

PduX protein involved in propanediol utilization and related proteins [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 443608 [Multi-domain]  Cd Length: 286  Bit Score: 269.42  E-value: 4.24e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917536364   9 RAAAGISYCSFGELLQGVLleDESDFLVTLPIRKYSVSTFVPDHGSSeivtqPSGKTKAAALARVILARHGRT-VGGTFH 87
Cdd:COG4542    2 TMGTARCPGSCGELLQGWI--GGREFLVTCPIDLYSTVTVEPGPGGI-----PAERPKARRAAELTLEHLGLPpLGGRIE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917536364  88 IDCDIPVGKGLSSSSADLLATARAIEVYLGRELPLEQLCRDMSGIEPTDGVMFAESVVYLQRKGMLRARLGRLPNLQIVS 167
Cdd:COG4542   75 LRSDIPVGKGMASSTADIAATARAVARALGKELSPEELARLAVAIEPTDSTMFPGLVLFDHREGRVLEPLGPLPPLDILG 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917536364 168 LDEGGTLDTLEYHRGGeANRHNREHRAEFNELLERIVAAFAARDLAEIGRVSTRSAQINQKVNPKRHLAAVQDVSAATGG 247
Cdd:COG4542  155 LDSGGTVDTLAFNRRD-LAELNRAEEPEIERALALLREALRTGDLALLGEAATLSARANQRILPKPELEELLALAEELGA 233

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 917536364 248 LGLVTAHSGTCIGILYEAGRADHAANLARAVDALSAHGSVRVY 290
Cdd:COG4542  234 LGVNVAHSGTVLGLLFDPGDHDVEKLAEALRRRLLRLGYPRIG 276
 
Name Accession Description Interval E-value
PduX COG4542
PduX protein involved in propanediol utilization and related proteins [Secondary metabolites ...
 9-290 4.24e-90

PduX protein involved in propanediol utilization and related proteins [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443608 [Multi-domain]  Cd Length: 286  Bit Score: 269.42  E-value: 4.24e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917536364   9 RAAAGISYCSFGELLQGVLleDESDFLVTLPIRKYSVSTFVPDHGSSeivtqPSGKTKAAALARVILARHGRT-VGGTFH 87
Cdd:COG4542    2 TMGTARCPGSCGELLQGWI--GGREFLVTCPIDLYSTVTVEPGPGGI-----PAERPKARRAAELTLEHLGLPpLGGRIE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917536364  88 IDCDIPVGKGLSSSSADLLATARAIEVYLGRELPLEQLCRDMSGIEPTDGVMFAESVVYLQRKGMLRARLGRLPNLQIVS 167
Cdd:COG4542   75 LRSDIPVGKGMASSTADIAATARAVARALGKELSPEELARLAVAIEPTDSTMFPGLVLFDHREGRVLEPLGPLPPLDILG 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917536364 168 LDEGGTLDTLEYHRGGeANRHNREHRAEFNELLERIVAAFAARDLAEIGRVSTRSAQINQKVNPKRHLAAVQDVSAATGG 247
Cdd:COG4542  155 LDSGGTVDTLAFNRRD-LAELNRAEEPEIERALALLREALRTGDLALLGEAATLSARANQRILPKPELEELLALAEELGA 233

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 917536364 248 LGLVTAHSGTCIGILYEAGRADHAANLARAVDALSAHGSVRVY 290
Cdd:COG4542  234 LGVNVAHSGTVLGLLFDPGDHDVEKLAEALRRRLLRLGYPRIG 276
GHMP_kinases_N pfam00288
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and ...
 85-128 9.12e-07

GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and mevalonate kinases.


Pssm-ID: 395225 [Multi-domain]  Cd Length: 64  Bit Score: 45.23  E-value: 9.12e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 917536364   85 TFHIDCDIPVGKGLSSSSADLLATARAIEVYLGreLPLEQLCRD 128
Cdd:pfam00288   1 DIEIESNIPLGAGLGSSAALAVALLLALNELFG--LPLAKLALE 42
PRK01212 PRK01212
homoserine kinase; Provisional
 71-133 6.34e-03

homoserine kinase; Provisional


Pssm-ID: 234920 [Multi-domain]  Cd Length: 301  Bit Score: 37.44  E-value: 6.34e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917536364  71 ARVILARHGRTVGGTFHIDCDIPVGKGLSSSSADLLATARAIEVYLGRELPLEQLCRDMSGIE 133
Cdd:PRK01212  69 ALKFLEKLGKPPGLRIELEKNIPLGRGLGSSAASIVAGLVAANELAGLPLSKEELLQLATEGE 131
 
Name Accession Description Interval E-value
PduX COG4542
PduX protein involved in propanediol utilization and related proteins [Secondary metabolites ...
 9-290 4.24e-90

PduX protein involved in propanediol utilization and related proteins [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443608 [Multi-domain]  Cd Length: 286  Bit Score: 269.42  E-value: 4.24e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917536364   9 RAAAGISYCSFGELLQGVLleDESDFLVTLPIRKYSVSTFVPDHGSSeivtqPSGKTKAAALARVILARHGRT-VGGTFH 87
Cdd:COG4542    2 TMGTARCPGSCGELLQGWI--GGREFLVTCPIDLYSTVTVEPGPGGI-----PAERPKARRAAELTLEHLGLPpLGGRIE 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917536364  88 IDCDIPVGKGLSSSSADLLATARAIEVYLGRELPLEQLCRDMSGIEPTDGVMFAESVVYLQRKGMLRARLGRLPNLQIVS 167
Cdd:COG4542   75 LRSDIPVGKGMASSTADIAATARAVARALGKELSPEELARLAVAIEPTDSTMFPGLVLFDHREGRVLEPLGPLPPLDILG 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917536364 168 LDEGGTLDTLEYHRGGeANRHNREHRAEFNELLERIVAAFAARDLAEIGRVSTRSAQINQKVNPKRHLAAVQDVSAATGG 247
Cdd:COG4542  155 LDSGGTVDTLAFNRRD-LAELNRAEEPEIERALALLREALRTGDLALLGEAATLSARANQRILPKPELEELLALAEELGA 233

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 917536364 248 LGLVTAHSGTCIGILYEAGRADHAANLARAVDALSAHGSVRVY 290
Cdd:COG4542  234 LGVNVAHSGTVLGLLFDPGDHDVEKLAEALRRRLLRLGYPRIG 276
ERG12 COG1577
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ...
 67-217 2.92e-07

Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441185 [Multi-domain]  Cd Length: 277  Bit Score: 50.61  E-value: 2.92e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917536364  67 AAALARVILARHGRTVGGTFHIDCDIPVGKGLSSSSADLLATARAIEVYLGRELPLEQLCR---DM--------SGIEPT 135
Cdd:COG1577   65 KAAIEAALEYLGLPLKGFDIEIDSEIPRKRGLGSSAAVAVAVIRALAAFYGVELSKEELFKlalEAekivhgnpSGLDTA 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917536364 136 dgVMFAESVVYLQRKGMLRaRLGRLPNLQIVSLDEGGTLDTLEY----HRGGEANRHNREHR-AEFNELLERIVAAFAAR 210
Cdd:COG1577  145 --ASTYGGPIYYQRGDRAE-PLELPKNLPLVVGDTGVPASTKELvakvRKLKERNPELYEAFlEEIGDLVEEAIEALEEG 221


                 ....*..
gi 917536364 211 DLAEIGR 217
Cdd:COG1577  222 DLEALGE 228
GHMP_kinases_N pfam00288
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and ...
 85-128 9.12e-07

GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and mevalonate kinases.


Pssm-ID: 395225 [Multi-domain]  Cd Length: 64  Bit Score: 45.23  E-value: 9.12e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 917536364   85 TFHIDCDIPVGKGLSSSSADLLATARAIEVYLGreLPLEQLCRD 128
Cdd:pfam00288   1 DIEIESNIPLGAGLGSSAALAVALLLALNELFG--LPLAKLALE 42
COG2605 COG2605
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction ...
 69-133 6.86e-05

Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only];


Pssm-ID: 442017 [Multi-domain]  Cd Length: 328  Bit Score: 43.63  E-value: 6.86e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 917536364  69 ALARVILARHGRTVGGTFHIDCDIPVGKGLSSSSADLLATARAIEVYLGRELPLEQLCRDMSGIE 133
Cdd:COG2605   72 PVIREALKLFGIGDGLEITTDSDAPAGSGLGSSSALTVALLNALHALLGLPLSPYDLARLAYEIE 136
AroK2 COG1685
Archaeal shikimate kinase [Amino acid transport and metabolism]; Archaeal shikimate kinase is ...
 71-127 4.32e-04

Archaeal shikimate kinase [Amino acid transport and metabolism]; Archaeal shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 441291  Cd Length: 282  Bit Score: 40.97  E-value: 4.32e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 917536364  71 ARVILARHGRTVGGTFHIDCDIPVGKGLSSSSA----DLLATARAievyLGRELPLEQLCR 127
Cdd:COG1685   62 VELVLERFGDGNGGTVRTESEIPTASGLKSSSAaanaTVLATLDA----LGEDMDDLDALR 118
GalK COG0153
Galactokinase [Carbohydrate transport and metabolism];
75-125 6.04e-04

Galactokinase [Carbohydrate transport and metabolism];


Pssm-ID: 439923 [Multi-domain]  Cd Length: 380  Bit Score: 40.91  E-value: 6.04e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 917536364  75 LARHGRTVGG-TFHIDCDIPVGKGLSSSSADLLATARAIEVYLGRELPLEQL 125
Cdd:COG0153   99 LQERGYKLGGfDLVIDGDVPLGAGLSSSAALEVAVALALNDLFGLGLDPVEL 150
ThrB COG0083
Homoserine kinase [Amino acid transport and metabolism]; Homoserine kinase is part of the ...
 71-133 5.45e-03

Homoserine kinase [Amino acid transport and metabolism]; Homoserine kinase is part of the Pathway/BioSystem: Threonine biosynthesis


Pssm-ID: 439853 [Multi-domain]  Cd Length: 302  Bit Score: 37.77  E-value: 5.45e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 917536364  71 ARVILARHGRTVGG-TFHIDCDIPVGKGLSSSSADLLATARAIEVYLGRELPLEQLCRDMSGIE 133
Cdd:COG0083   65 ALALLEKLGKEPPGlRIEIEKGIPLGRGLGSSAAAIVAGLVAANALLGLPLSKEELLELATEGE 128
PRK01212 PRK01212
homoserine kinase; Provisional
 71-133 6.34e-03

homoserine kinase; Provisional


Pssm-ID: 234920 [Multi-domain]  Cd Length: 301  Bit Score: 37.44  E-value: 6.34e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 917536364  71 ARVILARHGRTVGGTFHIDCDIPVGKGLSSSSADLLATARAIEVYLGRELPLEQLCRDMSGIE 133
Cdd:PRK01212  69 ALKFLEKLGKPPGLRIELEKNIPLGRGLGSSAASIVAGLVAANELAGLPLSKEELLQLATEGE 131
PRK03188 PRK03188
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional
 61-126 8.75e-03

4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional


Pssm-ID: 235110 [Multi-domain]  Cd Length: 300  Bit Score: 37.18  E-value: 8.75e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 917536364  61 PSGKTKAAALARVILARH-GRTVGGTFHIDCDIPVGKGLSSSSADLLATARAIEVYLGRELPLEQLC 126
Cdd:PRK03188  60 PTDESNLAWRAAELLAEHvGRAPDVHLHIDKGIPVAGGMAGGSADAAAALVACDALWGLGLSRDELL 126
PRK03817 PRK03817
galactokinase; Provisional
 74-127 9.00e-03

galactokinase; Provisional


Pssm-ID: 235163 [Multi-domain]  Cd Length: 351  Bit Score: 37.28  E-value: 9.00e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 917536364  74 ILARHGRTVGG-TFHIDCDIPVGKGLSSSSADLLATARAIEVYLGRELPLEQLCR 127
Cdd:PRK03817  76 VLEKRGYEVGGvKGKVSSNLPIGAGLSSSASLEVAVAYALNEAYNLNLSKLELAL 130
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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