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Conserved domains on  [gi|917665541|ref|WP_052219378|]
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MULTISPECIES: single-stranded DNA-binding protein [Enterobacterales]

Protein Classification

single-stranded DNA-binding protein( domain architecture ID 11427956)

single-stranded DNA (ssDNA)-binding protein plays a key role in DNA replication, recombination, and repair

CATH:  2.40.50.140
Gene Ontology:  GO:0003697|GO:0006260
PubMed:  12598368|8458342|27838363
SCOP:  4000346

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
7-96 3.81e-07

Single-stranded DNA-binding protein [Replication, recombination and repair];


:

Pssm-ID: 440394  Cd Length: 116  Bit Score: 47.14  E-value: 3.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917665541   7 GKVAIDP--RYTPaknGNDSVIFFRLGCEMKI-----NSQKVIEFFPIKAFGKVADFLHNTIKKDSEISIEAIARTARYV 79
Cdd:COG0629    8 GRLGKDPelRYTP---SGTAVANFRLAVNRRYkdqdgEWKDETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLRTRSWE 84

                         90
                 ....*....|....*...
gi 917665541  80 -KDGSDVQRTEFHAFSVH 96
Cdd:COG0629   85 dKDGQKRYTTEVVADEIQ 102
 
Name Accession Description Interval E-value
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
7-96 3.81e-07

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 47.14  E-value: 3.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917665541   7 GKVAIDP--RYTPaknGNDSVIFFRLGCEMKI-----NSQKVIEFFPIKAFGKVADFLHNTIKKDSEISIEAIARTARYV 79
Cdd:COG0629    8 GRLGKDPelRYTP---SGTAVANFRLAVNRRYkdqdgEWKDETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLRTRSWE 84

                         90
                 ....*....|....*...
gi 917665541  80 -KDGSDVQRTEFHAFSVH 96
Cdd:COG0629   85 dKDGQKRYTTEVVADEIQ 102
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 7-92 7.54e-07

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 46.07  E-value: 7.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917665541    7 GKVAIDP--RYTPakNGNdSVIFFRLGC----EMKINSQKVIEFFPIKAFGKVADFLHNTIKKDSEISIEAIARTARY-V 79
Cdd:pfam00436   8 GRLTRDPelRYTP--NGN-AVANFTLATnrrfKDRGEGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQTRKYeD 84

                          90
                  ....*....|...
gi 917665541   80 KDGSDVQRTEFHA 92
Cdd:pfam00436  85 QEGQKRYVTEIVA 97
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 7-89 1.66e-03

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 37.78  E-value: 1.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917665541    7 GKVAIDP--RYTPAKNgndSVIFFRLGCEMKINSQ-----KVIEFFPIKAFGKVADFLHNTIKKDSEISIEAIARTARYV 79
Cdd:TIGR00621  11 GRLTRDPelRYTPSGN---AVANFTLATNRRWKDQdgewkEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLRTRKWE 87

                          90
                  ....*....|.
gi 917665541   80 -KDGSDVQRTE 89
Cdd:TIGR00621  88 dQNGQKRSKTE 98
 
Name Accession Description Interval E-value
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
7-96 3.81e-07

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 47.14  E-value: 3.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917665541   7 GKVAIDP--RYTPaknGNDSVIFFRLGCEMKI-----NSQKVIEFFPIKAFGKVADFLHNTIKKDSEISIEAIARTARYV 79
Cdd:COG0629    8 GRLGKDPelRYTP---SGTAVANFRLAVNRRYkdqdgEWKDETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLRTRSWE 84

                         90
                 ....*....|....*...
gi 917665541  80 -KDGSDVQRTEFHAFSVH 96
Cdd:COG0629   85 dKDGQKRYTTEVVADEIQ 102
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 7-92 7.54e-07

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 46.07  E-value: 7.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917665541    7 GKVAIDP--RYTPakNGNdSVIFFRLGC----EMKINSQKVIEFFPIKAFGKVADFLHNTIKKDSEISIEAIARTARY-V 79
Cdd:pfam00436   8 GRLTRDPelRYTP--NGN-AVANFTLATnrrfKDRGEGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQTRKYeD 84

                          90
                  ....*....|...
gi 917665541   80 KDGSDVQRTEFHA 92
Cdd:pfam00436  85 QEGQKRYVTEIVA 97
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 7-89 1.66e-03

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 37.78  E-value: 1.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 917665541    7 GKVAIDP--RYTPAKNgndSVIFFRLGCEMKINSQ-----KVIEFFPIKAFGKVADFLHNTIKKDSEISIEAIARTARYV 79
Cdd:TIGR00621  11 GRLTRDPelRYTPSGN---AVANFTLATNRRWKDQdgewkEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLRTRKWE 87

                          90
                  ....*....|.
gi 917665541   80 -KDGSDVQRTE 89
Cdd:TIGR00621  88 dQNGQKRSKTE 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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