|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
14-451 |
5.67e-174 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 492.38 E-value: 5.67e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 14 IVDLTHEGHGVIKIDRYPIFVPNALIGEVIKYKIIKVKKNFAIGKLLQVIKPSEQRVEPPCKYYWKCGGCQLQHMTYDAQ 93
Cdd:COG2265 7 IEDLAHGGDGVARHDGKVVFVPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFGRCGGCQLQHLSYEAQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 94 LAMKQSQVTNLFHRKAQFSNTIINKTIGMNHPWHYRNKSQLPIGKDrDGKAIIGYYRQRSHDIIDMDSCLIQDDIHQDIM 173
Cdd:COG2265 87 LELKQRVVREALERIGGLPEVEVEPIIGSPEPWGYRNRARLSVRRT-DGRLRLGFYARGSHELVDIDECPLLDPALNALL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 174 NHVKQWIIDYDisvynecTKKGLLRHLVIRTGyysddkmvvfvtngknfqqasilveklketfpniasikqninnshsnv 253
Cdd:COG2265 166 PALRELLAELG-------ARRGELRHLVVRAG------------------------------------------------ 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 254 imgqqsvtlygKDKIADQLSDTTFKISDQSFYQINSSQTEKLYQKAIEYAQLTGEETVLDTYCGIGTIGLYMASVAKHVY 333
Cdd:COG2265 191 -----------RDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPLARRAKKVI 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 334 GVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKWKqQGIKPDVVMVDPPRKGCDETFLQTLLKLNPKRIVYISCNP 413
Cdd:COG2265 260 GVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELL-WGGRPDVVVLDPPRAGAGPEVLEALAALGPRRIVYVSCNP 338
|
410 420 430
....*....|....*....|....*....|....*....
gi 920617300 414 STQQRDAQILDSQ-YELQEITPVDMFPQTTHVETVALFE 451
Cdd:COG2265 339 ATLARDLALLVEGgYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
17-445 |
6.06e-159 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 456.21 E-value: 6.06e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 17 LTHEGHGVIKIDRYPIFVPNALIGEVIKYKIIKVKKNFAIGKLLQVIKPSEQRVEPPCKYYWKCGGCQLQHMTYDAQLAM 96
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVFVPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQHLSYELQLRS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 97 KQSQVTNLFHR--KAQFSNTIINKTIGMNhPWHYRNKSQLPIGKDRDGKAIIGYYRQRSHDIIDMDSCLIQDDIHQDIMN 174
Cdd:TIGR00479 81 KQQQVIALLERigKFVSEPIEDVPTIGDD-PWGYRNKARLSLGRSPSGQLQAGFYQKGSHDIVDVKQCPVQAPALNALLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 175 HVKQWIIDYDISVYNECTKKGLLRHLVIRTGYYSDDKMVVFVTNGKNFQQASILVEKLKETFPNIASIKQNINNSHSNVI 254
Cdd:TIGR00479 160 KVRAILENFGASRYLEHKELGQARHGVLRIGRHTGELSSVDRTALERFPHKEELDLYLQPDSPDVKSICQNINPEKTNVI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 255 MGQQSVTLYGKDKIADQLSDTTFKISDQSFYQINSSQTEKLYQKAIEYAQLTGEETVLDTYCGIGTIGLYMASVAKHVYG 334
Cdd:TIGR00479 240 FGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 335 VEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKWKQQGIKPDVVMVDPPRKGCDETFLQTLLKLNPKRIVYISCNPS 414
Cdd:TIGR00479 320 VEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPERIVYVSCNPA 399
|
410 420 430
....*....|....*....|....*....|..
gi 920617300 415 TQQRDAQIL-DSQYELQEITPVDMFPQTTHVE 445
Cdd:TIGR00479 400 TLARDLEALcKAGYTIARVQPVDMFPHTGHVE 431
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
13-453 |
1.22e-80 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 256.24 E-value: 1.22e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 13 NIVDLTHEGHGVIKIDRYPIFVPNALIGEVIKYKIIKVKKNFAIGKLLQVIKPSEQRVEPPCKYYWKCGGCQLQHMTYDA 92
Cdd:PRK13168 19 TIESLDHDGRGVARHNGKTVFIEGALPGERVEVQVTEDKKQYARAKVVRILKPSPERVTPRCPHFGVCGGCQLQHLSIDA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 93 QLAMKQSQVTNLFHRKAQFSNTIINKTIgMNHPWHYRNKSQLPIGKD-RDGKAIIGYYRQRSHDIIDMDSCLIQDDIHQD 171
Cdd:PRK13168 99 QIASKQRALEDLLKHLAGVEPEEVLPPI-AGPPWGYRRRARLSVRYVpKKGQLLVGFREKNSSDIVDIDQCPVLVPPLSA 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 172 IMNHVKQWIidydisvyNECTKKGLLRH--LVIrtgyySDDKMVVFVTNGKNFQQASIlvEKLKEtFpniasikqninnS 249
Cdd:PRK13168 178 LLPPLRALL--------SSLSAKRRLGHveLAQ-----GDNGTALVLRHLEPLSEADR--AKLRA-F------------A 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 250 HSNVIM------GQQSVTLYGKDkiADQLSDT--------TFKISDqsFYQINSSQTEKLYQKAIEYAQLTGEETVLDTY 315
Cdd:PRK13168 230 EQHGLQlylqpkGPDLVHLLGPA--DAQLSYYlpefglrlAFSPRD--FIQVNAQVNQKMVARALEWLDPQPGDRVLDLF 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 316 CGIGTIGLYMASVAKHVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIK--WKQQGIkpDVVMVDPPRKGCDET 393
Cdd:PRK13168 306 CGLGNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVTFYHANLEEDFTDqpWALGGF--DKVLLDPPRAGAAEV 383
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 920617300 394 fLQTLLKLNPKRIVYISCNPSTQQRDAQILDSQ-YELQEITPVDMFPQTTHVETVALFERK 453
Cdd:PRK13168 384 -MQALAKLGPKRIVYVSCNPATLARDAGVLVEAgYRLKRAGMLDMFPHTGHVESMALFERG 443
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
89-453 |
5.02e-18 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 85.18 E-value: 5.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 89 TYDAQLAMKQSQVTNLFhrkAQFSNTIINktIGMNHPWHYRNKSQLPIGKDRDGKAIIgYYRQRSHDIIDMDSCLIQDDI 168
Cdd:pfam05958 1 QYDAQLAEKKSRLKALF---APFYAPDPE--VFASPDKHYRMRAEFRIWHEGDDLYYA-MFDQQTKSRIRVDQFPAASEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 169 HQDIMNHVKQWIIDydisvynectkKGLLRHLVIRTGYYS--DDKMVVFVTNGKNF-----QQASILVEKLKETFPNIAS 241
Cdd:pfam05958 75 INELMPALIAALRQ-----------DPALRHKLFQVDFLTtlSGEALVSLLYHKQLddewrQAAEALRDALRAQGLDVNL 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 242 I----KQNINNSHSNVimgQQSVTLYGKDKIADQLSDttfkisdqSFYQINSSQTEKLYQKAIEYAQlTGEETVLDTYCG 317
Cdd:pfam05958 144 IgrarKQKIVLDQDYV---DETLPVAGREFIYRQVEN--------SFTQPNAAVNIKMLEWACDVTQ-GSKGDLLELYCG 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 318 IGTIGLYMASVAKHVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKWKQ-------QGIKPD-----VVMVDP 385
Cdd:pfam05958 212 NGNFSLALARNFRKVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMNGvrefnrlKGIDLKsyncsTIFVDP 291
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 920617300 386 PRKGCDETFLQtLLKLNPkRIVYISCNPSTQQRDAQILDSQYELQEITPVDMFPQTTHVETVALFERK 453
Cdd:pfam05958 292 PRAGLDPETLK-LVQAYP-RILYISCNPETLCANLEQLSKTHRVERFALFDQFPYTHHMECGVLLEKK 357
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
310-411 |
4.80e-11 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 59.37 E-value: 4.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 310 TVLDTYCGIGTIGLYMAS-VAKHVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKwkqQGIKPDVVMVDPPRK 388
Cdd:cd02440 1 RVLDLGCGTGALALALASgPGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPE---ADESFDVIISDPPLH 77
|
90 100
....*....|....*....|....*..
gi 920617300 389 GCDETFLQTLLK----LNPKRIVYISC 411
Cdd:cd02440 78 HLVEDLARFLEEarrlLKPGGVLVLTL 104
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
14-451 |
5.67e-174 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 492.38 E-value: 5.67e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 14 IVDLTHEGHGVIKIDRYPIFVPNALIGEVIKYKIIKVKKNFAIGKLLQVIKPSEQRVEPPCKYYWKCGGCQLQHMTYDAQ 93
Cdd:COG2265 7 IEDLAHGGDGVARHDGKVVFVPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFGRCGGCQLQHLSYEAQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 94 LAMKQSQVTNLFHRKAQFSNTIINKTIGMNHPWHYRNKSQLPIGKDrDGKAIIGYYRQRSHDIIDMDSCLIQDDIHQDIM 173
Cdd:COG2265 87 LELKQRVVREALERIGGLPEVEVEPIIGSPEPWGYRNRARLSVRRT-DGRLRLGFYARGSHELVDIDECPLLDPALNALL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 174 NHVKQWIIDYDisvynecTKKGLLRHLVIRTGyysddkmvvfvtngknfqqasilveklketfpniasikqninnshsnv 253
Cdd:COG2265 166 PALRELLAELG-------ARRGELRHLVVRAG------------------------------------------------ 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 254 imgqqsvtlygKDKIADQLSDTTFKISDQSFYQINSSQTEKLYQKAIEYAQLTGEETVLDTYCGIGTIGLYMASVAKHVY 333
Cdd:COG2265 191 -----------RDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPLARRAKKVI 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 334 GVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKWKqQGIKPDVVMVDPPRKGCDETFLQTLLKLNPKRIVYISCNP 413
Cdd:COG2265 260 GVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELL-WGGRPDVVVLDPPRAGAGPEVLEALAALGPRRIVYVSCNP 338
|
410 420 430
....*....|....*....|....*....|....*....
gi 920617300 414 STQQRDAQILDSQ-YELQEITPVDMFPQTTHVETVALFE 451
Cdd:COG2265 339 ATLARDLALLVEGgYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
17-445 |
6.06e-159 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 456.21 E-value: 6.06e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 17 LTHEGHGVIKIDRYPIFVPNALIGEVIKYKIIKVKKNFAIGKLLQVIKPSEQRVEPPCKYYWKCGGCQLQHMTYDAQLAM 96
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVFVPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQHLSYELQLRS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 97 KQSQVTNLFHR--KAQFSNTIINKTIGMNhPWHYRNKSQLPIGKDRDGKAIIGYYRQRSHDIIDMDSCLIQDDIHQDIMN 174
Cdd:TIGR00479 81 KQQQVIALLERigKFVSEPIEDVPTIGDD-PWGYRNKARLSLGRSPSGQLQAGFYQKGSHDIVDVKQCPVQAPALNALLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 175 HVKQWIIDYDISVYNECTKKGLLRHLVIRTGYYSDDKMVVFVTNGKNFQQASILVEKLKETFPNIASIKQNINNSHSNVI 254
Cdd:TIGR00479 160 KVRAILENFGASRYLEHKELGQARHGVLRIGRHTGELSSVDRTALERFPHKEELDLYLQPDSPDVKSICQNINPEKTNVI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 255 MGQQSVTLYGKDKIADQLSDTTFKISDQSFYQINSSQTEKLYQKAIEYAQLTGEETVLDTYCGIGTIGLYMASVAKHVYG 334
Cdd:TIGR00479 240 FGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 335 VEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKWKQQGIKPDVVMVDPPRKGCDETFLQTLLKLNPKRIVYISCNPS 414
Cdd:TIGR00479 320 VEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPERIVYVSCNPA 399
|
410 420 430
....*....|....*....|....*....|..
gi 920617300 415 TQQRDAQIL-DSQYELQEITPVDMFPQTTHVE 445
Cdd:TIGR00479 400 TLARDLEALcKAGYTIARVQPVDMFPHTGHVE 431
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
13-453 |
1.22e-80 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 256.24 E-value: 1.22e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 13 NIVDLTHEGHGVIKIDRYPIFVPNALIGEVIKYKIIKVKKNFAIGKLLQVIKPSEQRVEPPCKYYWKCGGCQLQHMTYDA 92
Cdd:PRK13168 19 TIESLDHDGRGVARHNGKTVFIEGALPGERVEVQVTEDKKQYARAKVVRILKPSPERVTPRCPHFGVCGGCQLQHLSIDA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 93 QLAMKQSQVTNLFHRKAQFSNTIINKTIgMNHPWHYRNKSQLPIGKD-RDGKAIIGYYRQRSHDIIDMDSCLIQDDIHQD 171
Cdd:PRK13168 99 QIASKQRALEDLLKHLAGVEPEEVLPPI-AGPPWGYRRRARLSVRYVpKKGQLLVGFREKNSSDIVDIDQCPVLVPPLSA 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 172 IMNHVKQWIidydisvyNECTKKGLLRH--LVIrtgyySDDKMVVFVTNGKNFQQASIlvEKLKEtFpniasikqninnS 249
Cdd:PRK13168 178 LLPPLRALL--------SSLSAKRRLGHveLAQ-----GDNGTALVLRHLEPLSEADR--AKLRA-F------------A 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 250 HSNVIM------GQQSVTLYGKDkiADQLSDT--------TFKISDqsFYQINSSQTEKLYQKAIEYAQLTGEETVLDTY 315
Cdd:PRK13168 230 EQHGLQlylqpkGPDLVHLLGPA--DAQLSYYlpefglrlAFSPRD--FIQVNAQVNQKMVARALEWLDPQPGDRVLDLF 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 316 CGIGTIGLYMASVAKHVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIK--WKQQGIkpDVVMVDPPRKGCDET 393
Cdd:PRK13168 306 CGLGNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVTFYHANLEEDFTDqpWALGGF--DKVLLDPPRAGAAEV 383
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 920617300 394 fLQTLLKLNPKRIVYISCNPSTQQRDAQILDSQ-YELQEITPVDMFPQTTHVETVALFERK 453
Cdd:PRK13168 384 -MQALAKLGPKRIVYVSCNPATLARDAGVLVEAgYRLKRAGMLDMFPHTGHVESMALFERG 443
|
|
| meth_trns_rumB |
TIGR02085 |
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases ... |
74-452 |
1.31e-47 |
|
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases designated RumB, formerly YbjF. Members act on 23S rRNA U747 and the equivalent position in other proteobacterial species. This family is homologous to the other 23S rRNA methyltransferase RumA and to the tRNA methyltransferase TrmA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 131140 Cd Length: 374 Bit Score: 167.71 E-value: 1.31e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 74 CKYYW--KCGGCQLQHMTYDAQLAMKQSQVTNLF---HRKAQFSNTIINKTIGmnhpwhYRNKSQLPIGKDRDgKAIIGY 148
Cdd:TIGR02085 2 CAFYIqgRCRSCQWLAQPYSEQLTNKQQHLKELLapnATVVQWLAPVTSAEQA------FRNKAKMVVSGSVE-RPILGI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 149 YrQRSHDIIDMDSCLIQDDIHQDIMNHVKQWIIDYDISVYNECTKKGLLRHLVIRTGYYSDDKMVVFVTNGKN-FQQASI 227
Cdd:TIGR02085 75 L-HRDGTPLDLCDCPLYPQSFQPVFAYLKNFIARAGLTPYNVAKKKGELKFILLTESENSGQLMLRFVLRSETkLAQIRR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 228 LVEKLKETFPNIASIKQNINNSHSNVIMGQQSVTLYGKDKIADQLSDTTFKISDQSFYQINSSQTEKLYQKAIEYAQLTG 307
Cdd:TIGR02085 154 ALPWLIEQLPQLEVISVNIQPVHMAILEGEEEIFLTEQQALPERFNDVPLVIRPQSFFQTNPKVAAQLYATARQWVREIP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 308 EETVLDTYCGIGTIGLYMASVAKHVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIikwKQQGIKPDVVMVDPPR 387
Cdd:TIGR02085 234 VTQMWDLFCGVGGFGLHCAGPDTQLTGIEIESEAIACAQQSAQMLGLDNLSFAALDSAKFA---TAQMSAPELVLVNPPR 310
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 920617300 388 KGCDETFLQTLLKLNPKRIVYISCNPSTQQRDAQILDSqYELQEITPVDMFPQTTHVETVALFER 452
Cdd:TIGR02085 311 RGIGKELCDYLSQMAPKFILYSSCNAQTMAKDIAELSG-YQIERVQLFDMFPHTSHYEVLTLLVR 374
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
176-453 |
5.90e-46 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 161.58 E-value: 5.90e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 176 VKQWIIDYDISVYNECTKKGLLRHLVIRTGYYSDDKMVVFVTNGKNfQQASILVE--KLKETFPNIASIKQNINNSHSNV 253
Cdd:PRK03522 41 LKPFIARAGLTPYNVARKRGELKYILLTESQSDGELMLRFVLRSET-KLARLRRAlpWLQAQLPQLKVISVNIQPVHMAI 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 254 IMGQQSVTLYGKDKIADQLSDTTFKISDQSFYQINSSQTEKLYQKAIEYAQLTGEETVLDTYCGIGTIGLYMASVAKHVY 333
Cdd:PRK03522 120 LEGEEEIFLTEQQALPERFNGVPLFIRPQSFFQTNPAVAAQLYATARDWVRELPPRSMWDLFCGVGGFGLHCATPGMQLT 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 334 GVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIikwKQQGIKPDVVMVDPPRKGCDETFLQTLLKLNPKRIVYISCNP 413
Cdd:PRK03522 200 GIEISAEAIACAKQSAAELGLTNVQFQALDSTQFA---TAQGEVPDLVLVNPPRRGIGKELCDYLSQMAPRFILYSSCNA 276
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 920617300 414 STQQRDAQILdSQYELQEITPVDMFPQTTHVETVALFERK 453
Cdd:PRK03522 277 QTMAKDLAHL-PGYRIERVQLFDMFPHTAHYEVLTLLVRQ 315
|
|
| PRK05031 |
PRK05031 |
tRNA (uracil-5-)-methyltransferase; Validated |
80-453 |
5.67e-27 |
|
tRNA (uracil-5-)-methyltransferase; Validated
Pssm-ID: 235332 Cd Length: 362 Bit Score: 111.07 E-value: 5.67e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 80 CGGCQLQHMTYDAQLAMKQSQVTNLFhrkAQFSNTIInkTIGMNHPWHYRNKSQLPIGKDRDgkaiIGYY---RQRSHDI 156
Cdd:PRK05031 1 MTPECLPPEQYEAQLAEKVARLKELF---APFSAPEP--EVFRSPPSHYRMRAEFRIWHEGD----DLYYamfDQQTKQR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 157 IDMDSCLIQDDIHQDIM---------NHV---KQWIIDYdISvynecTKKG-----LLRHLVIrtgyysDDkmvvfvtng 219
Cdd:PRK05031 72 IRIDQFPIASELINALMpallaalraNPVlrhKLFQVDF-LS-----TLSGeilvsLLYHKKL------DE--------- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 220 kNFQQAsilVEKLKETFPNIASI----KQNINNSHSNVImgqQSVTLYGKDKIadqlsdttFKISDQSFYQINSsqteKL 295
Cdd:PRK05031 131 -EWEQA---AKALRDALFNVHLIgrsrKQKIVLDQDYVD---ERLPVAGREFI--------YRQVENSFTQPNA----AV 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 296 YQKAIEYAQ-LTGEET--VLDTYCGIGTIGLYMASVAKHVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKWK 372
Cdd:PRK05031 192 NEKMLEWALdATKGSKgdLLELYCGNGNFTLALARNFRRVLATEISKPSVAAAQYNIAANGIDNVQIIRMSAEEFTQAMN 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 373 Q-------QGIK-----PDVVMVDPPRKGCDETFLQtLLKlNPKRIVYISCNPSTQQRDAQILDSQYELQEITPVDMFPQ 440
Cdd:PRK05031 272 GvrefnrlKGIDlksynFSTIFVDPPRAGLDDETLK-LVQ-AYERILYISCNPETLCENLETLSQTHKVERFALFDQFPY 349
|
410
....*....|...
gi 920617300 441 TTHVETVALFERK 453
Cdd:PRK05031 350 THHMECGVLLEKK 362
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
89-453 |
5.02e-18 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 85.18 E-value: 5.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 89 TYDAQLAMKQSQVTNLFhrkAQFSNTIINktIGMNHPWHYRNKSQLPIGKDRDGKAIIgYYRQRSHDIIDMDSCLIQDDI 168
Cdd:pfam05958 1 QYDAQLAEKKSRLKALF---APFYAPDPE--VFASPDKHYRMRAEFRIWHEGDDLYYA-MFDQQTKSRIRVDQFPAASEL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 169 HQDIMNHVKQWIIDydisvynectkKGLLRHLVIRTGYYS--DDKMVVFVTNGKNF-----QQASILVEKLKETFPNIAS 241
Cdd:pfam05958 75 INELMPALIAALRQ-----------DPALRHKLFQVDFLTtlSGEALVSLLYHKQLddewrQAAEALRDALRAQGLDVNL 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 242 I----KQNINNSHSNVimgQQSVTLYGKDKIADQLSDttfkisdqSFYQINSSQTEKLYQKAIEYAQlTGEETVLDTYCG 317
Cdd:pfam05958 144 IgrarKQKIVLDQDYV---DETLPVAGREFIYRQVEN--------SFTQPNAAVNIKMLEWACDVTQ-GSKGDLLELYCG 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 318 IGTIGLYMASVAKHVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKWKQ-------QGIKPD-----VVMVDP 385
Cdd:pfam05958 212 NGNFSLALARNFRKVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMNGvrefnrlKGIDLKsyncsTIFVDP 291
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 920617300 386 PRKGCDETFLQtLLKLNPkRIVYISCNPSTQQRDAQILDSQYELQEITPVDMFPQTTHVETVALFERK 453
Cdd:pfam05958 292 PRAGLDPETLK-LVQAYP-RILYISCNPETLCANLEQLSKTHRVERFALFDQFPYTHHMECGVLLEKK 357
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
310-411 |
4.80e-11 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 59.37 E-value: 4.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 310 TVLDTYCGIGTIGLYMAS-VAKHVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKwkqQGIKPDVVMVDPPRK 388
Cdd:cd02440 1 RVLDLGCGTGALALALASgPGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPE---ADESFDVIISDPPLH 77
|
90 100
....*....|....*....|....*..
gi 920617300 389 GCDETFLQTLLK----LNPKRIVYISC 411
Cdd:cd02440 78 HLVEDLARFLEEarrlLKPGGVLVLTL 104
|
|
| RlmK |
COG1092 |
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure ... |
303-386 |
5.80e-10 |
|
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure and biogenesis]; 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI is part of the Pathway/BioSystem: 23S rRNA modification
Pssm-ID: 440709 [Multi-domain] Cd Length: 392 Bit Score: 60.97 E-value: 5.80e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 303 AQLTGEETVLDTYCGIGTIGLYMASV-AKHVYGVEVVPSAIKDAQQNATLNGFENT-TFVCGKAEEVIIKWKQQGIKPDV 380
Cdd:COG1092 212 AELAKGKRVLNLFSYTGGFSVHAAAGgAKSVTSVDLSATALEWAKENAALNGLDDRhEFVQADAFDWLRELAREGERFDL 291
|
....*.
gi 920617300 381 VMVDPP 386
Cdd:COG1092 292 IILDPP 297
|
|
| Cons_hypoth95 |
pfam03602 |
Conserved hypothetical protein 95; |
310-409 |
1.25e-07 |
|
Conserved hypothetical protein 95;
Pssm-ID: 427391 [Multi-domain] Cd Length: 179 Bit Score: 51.47 E-value: 1.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 310 TVLDTYCGIGTIGLYMASV-AKHVYGVEVVPSAIKDAQQNATLNGFENTTFVcGKAEEVIIKWKQQGIKPDVVMVDPP-R 387
Cdd:pfam03602 44 RVLDLFAGSGALGLEALSRgAKRVTLVEKDKRAVQILKENLQLLGLPGAVLV-MDALLALLRLAGKGPVFDIVFLDPPyA 122
|
90 100
....*....|....*....|....*
gi 920617300 388 KGCDETFLQTLLK---LNPKRIVYI 409
Cdd:pfam03602 123 KGLIEEVLDLLAEkgwLKPNALIYV 147
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
309-386 |
1.35e-07 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 51.10 E-value: 1.35e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 920617300 309 ETVLDTYCGIGTIGLYMASVAKHVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKWKqqgiKPDVVMVDPP 386
Cdd:COG1041 28 DTVLDPFCGTGTILIEAGLLGRRVIGSDIDPKMVEGARENLEHYGYEDADVIRGDARDLPLADE----SVDAIVTDPP 101
|
|
| COG4076 |
COG4076 |
Predicted RNA methylase [General function prediction only]; |
296-384 |
2.24e-07 |
|
Predicted RNA methylase [General function prediction only];
Pssm-ID: 443253 [Multi-domain] Cd Length: 230 Bit Score: 51.58 E-value: 2.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 296 YQKAIEYAQLTGEeTVLDTYCGIGTIG-LYMASVAKHVYGVEVVPSAIKDAQQNATLNGF-ENTTFVCGKAEEViikwkQ 373
Cdd:COG4076 25 FKAAIERVVKPGD-VVLDIGTGSGLLSmLAARAGAKKVYAVEVNPDIAAVARRIIAANGLsDRITVINADATDL-----D 98
|
90
....*....|....
gi 920617300 374 QGIKPDVV---MVD 384
Cdd:COG4076 99 LPEKADVIiseMLD 112
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
302-386 |
6.45e-07 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 50.14 E-value: 6.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 302 YAQLTGEETVLDTYCGIGTIGLYMA--SVAKHVYGVEVVPSAIKDAQQNATLNGFEN-TTFVCGKAEEVIIKWKQQGIkp 378
Cdd:COG4123 32 FAPVKKGGRVLDLGTGTGVIALMLAqrSPGARITGVEIQPEAAELARRNVALNGLEDrITVIHGDLKEFAAELPPGSF-- 109
|
....*...
gi 920617300 379 DVVMVDPP 386
Cdd:COG4123 110 DLVVSNPP 117
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
305-381 |
1.44e-06 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 47.80 E-value: 1.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 305 LTGEETVLDTYCGIGTIGLYMASVA---KHVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKWKQQGIkpDVV 381
Cdd:pfam13847 1 IDKGMRVLDLGCGTGHLSFELAEELgpnAEVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEELPELLEDDKF--DVV 78
|
|
| Trm5 |
COG2520 |
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ... |
309-368 |
1.70e-06 |
|
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 442010 [Multi-domain] Cd Length: 333 Bit Score: 49.86 E-value: 1.70e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 920617300 309 ETVLDTYCGIGTIGLYMAS-VAKHVYGVEVVPSAIKDAQQNATLNGFENT-TFVCGKAEEVI 368
Cdd:COG2520 182 ERVLDMFAGVGPFSIPIAKrSGAKVVAIDINPDAVEYLKENIRLNKVEDRvTPILGDAREVA 243
|
|
| RsmD |
COG0742 |
16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
310-409 |
2.44e-06 |
|
16S rRNA G966 N2-methylase RsmD [Translation, ribosomal structure and biogenesis]; 16S rRNA G966 N2-methylase RsmD is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 440505 [Multi-domain] Cd Length: 183 Bit Score: 47.77 E-value: 2.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 310 TVLDTYCGIGTIGLYMASV-AKHVYGVEVVPSAIKDAQQNA-TLNGFENTTFVCGKAEEVIikWKQQGIKPDVVMVDPP- 386
Cdd:COG0742 44 RVLDLFAGSGALGLEALSRgAASVVFVEKDRKAAAVIRKNLeKLGLEDRARVIRGDALRFL--KRLAGEPFDLVFLDPPy 121
|
90 100
....*....|....*....|....*.
gi 920617300 387 RKGCDETFLQTLLK---LNPKRIVYI 409
Cdd:COG0742 122 AKGLLEKALELLAEnglLAPGGLIVV 147
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
295-366 |
3.25e-06 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 46.53 E-value: 3.25e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 920617300 295 LYQKAIEYAQLTGEETVLDTYCGIGTIGLYMASVAKHVYGVEVVPSAIKDAQQNATLNGFeNTTFVCGKAEE 366
Cdd:COG2226 10 GREALLAALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAED 80
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
300-360 |
6.33e-06 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 46.72 E-value: 6.33e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 920617300 300 IEYAQLTGEETVLDTYCGIGTIGLYMASVA--KHVYGVEVVPSAIKDAQQNATLNGFENTTFV 360
Cdd:COG2813 42 LEHLPEPLGGRVLDLGCGYGVIGLALAKRNpeARVTLVDVNARAVELARANAAANGLENVEVL 104
|
|
| Methyltransf_15 |
pfam09445 |
RNA cap guanine-N2 methyltransferase; RNA cap guanine-N2 methyltransferases such as ... |
309-386 |
9.12e-06 |
|
RNA cap guanine-N2 methyltransferase; RNA cap guanine-N2 methyltransferases such as Schizosaccharomyces pombe Tgs1 and Giardia lamblia Tgs2 catalyze methylation of the exocyclic N2 amine of 7-methylguanosine.
Pssm-ID: 370496 Cd Length: 165 Bit Score: 45.79 E-value: 9.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 309 ETVLDTYCGIG--TIGlyMASVAKHVYGVEVVPSAIKDAQQNATLNGFEN-TTFVCGKAEEVIIKWKQQGIKPDVVMVDP 385
Cdd:pfam09445 2 TRILDVFCGGGgnTIQ--FANVFDSVISIDINLEHLACAQHNAEVYGVSDrIWLIHGDWFELLAKLKFEKIKYDCVFASP 79
|
.
gi 920617300 386 P 386
Cdd:pfam09445 80 P 80
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
293-357 |
1.57e-05 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 45.27 E-value: 1.57e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 920617300 293 EKLYQKA------IEYAQLTGEETVLDTYCGIGTIGLYMASVAKHVYGVEVVPSAIKDAQQNATLNGFENT 357
Cdd:PRK14968 3 DEVYEPAedsfllAENAVDKKGDRVLEVGTGSGIVAIVAAKNGKKVVGVDINPYAVECAKCNAKLNNIRNN 73
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
297-366 |
1.71e-05 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 45.68 E-value: 1.71e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 920617300 297 QKAIEYAQLTGEETVLDTYCGIGTIGLYMAS-VAKHVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEE 366
Cdd:COG0500 16 ALLALLERLPKGGRVLDLGCGTGRNLLALAArFGGRVIGIDLSPEAIALARARAAKAGLGNVEFLVADLAE 86
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
316-366 |
1.46e-04 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 40.62 E-value: 1.46e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 920617300 316 CGIGTIGLYMAS-VAKHVYGVEVVPSAIKDAQQNATLNGFeNTTFVCGKAEE 366
Cdd:pfam13649 6 CGTGRLTLALARrGGARVTGVDLSPEMLERARERAAEAGL-NVEFVQGDAED 56
|
|
| ksgA |
PRK14896 |
16S ribosomal RNA methyltransferase A; |
297-340 |
2.06e-04 |
|
16S ribosomal RNA methyltransferase A;
Pssm-ID: 237852 [Multi-domain] Cd Length: 258 Bit Score: 42.97 E-value: 2.06e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 920617300 297 QKAIEYAQLTGEETVLDTYCGIGTIGLYMASVAKHVYGVEVVPS 340
Cdd:PRK14896 19 DRIVEYAEDTDGDPVLEIGPGKGALTDELAKRAKKVYAIELDPR 62
|
|
| PrmA |
pfam06325 |
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ... |
291-381 |
2.07e-04 |
|
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.
Pssm-ID: 428888 [Multi-domain] Cd Length: 294 Bit Score: 43.02 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 291 QTEKLYQKAIEyAQLTGEETVLDTYCGIGTigLYMASV---AKHVYGVEVVPSAIKDAQQNATLNGFENttfvcgkAEEV 367
Cdd:pfam06325 146 PTTKLCLEALE-RLVKPGESVLDVGCGSGI--LAIAALklgAKKVVGVDIDPVAVRAAKENAELNGVEA-------RLEV 215
|
90
....*....|....
gi 920617300 368 IIKWKQQGIKPDVV 381
Cdd:pfam06325 216 YLPGDLPKEKADVV 229
|
|
| COG3269 |
COG3269 |
Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; |
14-41 |
4.68e-04 |
|
Predicted RNA-binding protein, contains TRAM domain [General function prediction only];
Pssm-ID: 442500 [Multi-domain] Cd Length: 129 Bit Score: 40.04 E-value: 4.68e-04
10 20
....*....|....*....|....*...
gi 920617300 14 IVDLTHEGHGVIKIDRYPIFVPNALIGE 41
Cdd:COG3269 80 IEDIGKKGDGIARVEGFVIFVPGAEVGD 107
|
|
| Met_10 |
pfam02475 |
Met-10+ like-protein; The methionine-10 mutant allele of N. crassa codes for a protein of ... |
309-368 |
9.17e-04 |
|
Met-10+ like-protein; The methionine-10 mutant allele of N. crassa codes for a protein of unknown function, Swiss:O27901. However, homologous proteins have been found in yeast suggesting this protein may be involved in methionine biosynthesis, transport and/or utilization.
Pssm-ID: 396850 [Multi-domain] Cd Length: 198 Bit Score: 40.41 E-value: 9.17e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 920617300 309 ETVLDTYCGIG--TIGLYMASVAKHVYGVEVVPSAIKDAQQNATLNGFENTTF-VCGKAEEVI 368
Cdd:pfam02475 101 EVVVDMFAGIGpfSIPIAKHSKARRVYAIELNPESYKYLKENIKLNKVEDVVKpILGDVREVI 163
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
311-360 |
1.05e-03 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 39.88 E-value: 1.05e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 920617300 311 VLDTYCGIGTIGLYMASVAKH--VYGVEVVPSAIKDAQQNATLNGFENTTFV 360
Cdd:pfam05175 35 VLDLGCGAGVLGAALAKESPDaeLTMVDINARALESARENLAANGLENGEVV 86
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
310-367 |
1.21e-03 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 38.85 E-value: 1.21e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 920617300 310 TVLDTYCGIGTIGLYMASVAKHVYGVEVVPSAIKDAQQNAtlnGFENTTFVCGKAEEV 367
Cdd:COG2227 27 RVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERA---AELNVDFVQGDLEDL 81
|
|
| CobL |
COG2242 |
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part ... |
299-383 |
2.97e-03 |
|
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 441843 [Multi-domain] Cd Length: 403 Bit Score: 39.76 E-value: 2.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 299 AIEYAQLTGEETVLDTYCGIGTIGLYMASVAK--HVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEEVIIKWKqqgi 376
Cdd:COG2242 239 TLAKLALRPGDVLWDIGAGSGSVSIEAARLAPggRVYAIERDPERAALIRANARRFGVPNVEVVEGEAPEALADLP---- 314
|
....*..
gi 920617300 377 KPDVVMV 383
Cdd:COG2242 315 DPDAVFI 321
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
316-367 |
4.38e-03 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 36.49 E-value: 4.38e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 920617300 316 CGIGTIGLYMASVAKHVYGVEVVPSAIKDAQQNATLNGFentTFVCGKAEEV 367
Cdd:pfam08241 5 CGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGL---TFVVGDAEDL 53
|
|
| arsM |
PRK11873 |
arsenite methyltransferase; |
301-369 |
4.81e-03 |
|
arsenite methyltransferase;
Pssm-ID: 237007 [Multi-domain] Cd Length: 272 Bit Score: 38.78 E-value: 4.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 920617300 301 EYAQLTGEETVLDTYCGIGtIGLYMAS--VAK--HVYGVEVVPSAIKDAQQNATLNGFENTTFVCGKAEE---------V 367
Cdd:PRK11873 71 ALAELKPGETVLDLGSGGG-FDCFLAArrVGPtgKVIGVDMTPEMLAKARANARKAGYTNVEFRLGEIEAlpvadnsvdV 149
|
..
gi 920617300 368 II 369
Cdd:PRK11873 150 II 151
|
|
| |
