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Conserved domains on  [gi|923065875|ref|WP_053449524|]
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MULTISPECIES: outer membrane protein assembly factor BamB [Stenotrophomonas]

Protein Classification

PQQ-binding-like beta-propeller repeat protein( domain architecture ID 11445572)

PQQ (pyrrolo-quinoline quinone)-like beta-propeller repeat protein contains several instances of a beta-propeller repeat; similar to Bacillus subtilis protein YxaL

Gene Ontology:  GO:0070968
PubMed:  16232604|11831471|2549854

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 42-400 1.27e-153

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 438.48  E-value: 1.27e-153
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  42 EPAELVKFEPSVKVNKAWSVNLGKGERRIGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVWTwepqkekKKPKLRLSG 121
Cdd:COG1520   19 PPAPLPEFEPSVKVKQLWSASVGDGVGKGYSRLAPAVAGDRVYAADADGRVAALDAATGKELWR-------VDLGEPLSG 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 122 GPGVGENLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAPAVAQGLVFVRSNDGRVTAFDAGNGTQKWFNPSELPALT 201
Cdd:COG1520   92 GVGADGGLVVVGTEDGEVIALDADDGEELWRARLSSEVLAAPAVAGGRVVVRTGDGRVYALDAATGERLWSYQRPVPALT 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 202 VRGNAPVVTGPGVLFIGKDEGAVAALAQQDGRTLWEQNIGNGEGRTELERMADVDGAPVLEGNTLYVSSFKNQTMAIEGP 281
Cdd:COG1520  172 LRGTSSPVIVGGAVLVGFANGKLVALDLANGQPLWEQRVAQPRGRTELERLVDVDGTPVVDGGVVYAVAYQGRLAALDLR 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 282 TGRPLWARDHGGAGGVAVSSGNVFVTDNKGGVFGLDKATGAAMWSQTELARRSLTGPVLQGDYVVVGDYKGYVHWLKTSD 361
Cdd:COG1520  252 SGRVLWSRDLSSYTGLAVDGNNLYVTDDDGRVWALDRRNGAELWKQDALLYRGLTAPVVLGDYVVVGDFEGYLHWLSRDD 331

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 923065875 362 GAMAARAKSGGDALLAQPVVADGVLLVQNVDGKLTAFRL 400
Cdd:COG1520  332 GSLVARLRVDGSGIRAAPVVVGDTLYVQTRDGTLAALRL 370
 
Name Accession Description Interval E-value
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 42-400 1.27e-153

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 438.48  E-value: 1.27e-153
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  42 EPAELVKFEPSVKVNKAWSVNLGKGERRIGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVWTwepqkekKKPKLRLSG 121
Cdd:COG1520   19 PPAPLPEFEPSVKVKQLWSASVGDGVGKGYSRLAPAVAGDRVYAADADGRVAALDAATGKELWR-------VDLGEPLSG 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 122 GPGVGENLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAPAVAQGLVFVRSNDGRVTAFDAGNGTQKWFNPSELPALT 201
Cdd:COG1520   92 GVGADGGLVVVGTEDGEVIALDADDGEELWRARLSSEVLAAPAVAGGRVVVRTGDGRVYALDAATGERLWSYQRPVPALT 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 202 VRGNAPVVTGPGVLFIGKDEGAVAALAQQDGRTLWEQNIGNGEGRTELERMADVDGAPVLEGNTLYVSSFKNQTMAIEGP 281
Cdd:COG1520  172 LRGTSSPVIVGGAVLVGFANGKLVALDLANGQPLWEQRVAQPRGRTELERLVDVDGTPVVDGGVVYAVAYQGRLAALDLR 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 282 TGRPLWARDHGGAGGVAVSSGNVFVTDNKGGVFGLDKATGAAMWSQTELARRSLTGPVLQGDYVVVGDYKGYVHWLKTSD 361
Cdd:COG1520  252 SGRVLWSRDLSSYTGLAVDGNNLYVTDDDGRVWALDRRNGAELWKQDALLYRGLTAPVVLGDYVVVGDFEGYLHWLSRDD 331

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 923065875 362 GAMAARAKSGGDALLAQPVVADGVLLVQNVDGKLTAFRL 400
Cdd:COG1520  332 GSLVARLRVDGSGIRAAPVVVGDTLYVQTRDGTLAALRL 370
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 9-399 2.86e-143

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 412.40  E-value: 2.86e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875    9 RVATVLLMGMALTGCStvkgWFAGKDAAAkkaqEPAELVKFEPSVKVNKAWSVNLGKGERRIGVRQGPAVANGHVFAAAI 88
Cdd:TIGR03300   2 RLALVLACAALLSGCS----WFSSEDDEP----QPAELPEFQPTVKVDQVWSASVGDGVGHYYLRLQPAVAGGKVYAADA 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875   89 TGGVHAIDLQTGKKVWTwepqkekKKPKLRLSGGPGVGENLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAPAVAQG 168
Cdd:TIGR03300  74 DGTVAALDAETGKRLWR-------VDLDERLSGGVGADGGLVFVGTEKGEVIALDAEDGKELWRAKLSSEVLSPPLVANG 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  169 LVFVRSNDGRVTAFDAGNGTQKWFNPSELPALTVRGNAPVVTGPGVLFIGKDEGAVAALAQQDGRTLWEQNIGNGEGRTE 248
Cdd:TIGR03300 147 LVVVRTNDGRLTALDAATGERLWTYSRVTPPLTLRGSASPVIADGGVLVGFAGGKLVALDLQTGQPLWEQRVALPKGRTE 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  249 LERMADVDGAPVLEGNTLYVSSFKNQTMAIEGPTGRPLWARDHGGAGGVAVSSGNVFVTDNKGGVFGLDKATGAAMWSQT 328
Cdd:TIGR03300 227 LERLVDVDGDPVVDGGQVYAVSYQGRVAALDLRSGRVLWKRDASSYQGPAVDDNRLYVTDADGVVVALDRRSGSELWKND 306

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 923065875  329 ELARRSLTGPVLQGDYVVVGDYKGYVHWLKTSDGAMAARAKSGGDALLAQPVVADGVLLVQNVDGKLTAFR 399
Cdd:TIGR03300 307 ELKYRQLTAPAVLGGYLVVGDFEGYLHWLDRDDGSFVARLKTDGSGIASPPVVVGDGLLVQTRDGDLYAFR 377
BamB_YfgL cd10276
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ...
 42-400 4.06e-106

Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.


Pssm-ID: 199834 [Multi-domain]  Cd Length: 358  Bit Score: 316.97  E-value: 4.06e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  42 EPAELVKFEPSVKVNKAWSVNLGKGERRiGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVWtwepqKEKKKPKLRLSG 121
Cdd:cd10276    1 PPTDLPEPTPEFDPEVLWSKSVGNGGMA-GIDLTPVVAGDMVYAADANGQVSAFNATTGKIIW-----ETSLSGKGFLGG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 122 GPGVGENLVVIGTLDGQVIALDINDGSEKWRARVP-GEVIAAPAVAQGLVFVRSNDGRVTAFDAGNGTQKWFNPSELPAL 200
Cdd:cd10276   75 TPAVGNGKIFVGTESGYLYALDAKDGSELWRTEVSdSQLLSPPTYADGKIYVGTGDGRLYYCNAETGKVVWNRTSTAPEL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 201 TVRGNAPVVTGPGVLFIGKDEGAVAALAQQDGRTLWEQNIGNGEGRTELERMADVDGAPVLEGNTLYVSSFKNQTMAIEG 280
Cdd:cd10276  155 SLRGGAAPVGAYDVVFVGDGNGTVVALNTGTGVDIWEFSVSEPRGRTELPRMIDSSVTYVVVGGYLYSTSYQGYLVALDF 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 281 PTGRPLWARDH-GGAGGVAVSSGNVFVTDNKGGVFGLDKATGAAMWSQTELARRSLTGPVL-QGDYVVVGDY-KGYVHWL 357
Cdd:cd10276  235 ESGQFLWSRKAsGGTSTSTDANGRVYVGDGEGSLYCLDASTGDELWSQTVLLGRVLSSPAIyVGVYIYVTDNaEGYLYCL 314

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 923065875 358 KTSDGAMAARAK-SGGDALLAQPVVADGVLLVQNVDGKLTAFRL 400
Cdd:cd10276  315 KDNDGLTVARVEvDYSQYILQGPAVSDGWLYYGTDDGYLYALTR 358
PRK11138 PRK11138
outer membrane biogenesis protein BamB; Provisional
 44-400 2.63e-102

outer membrane biogenesis protein BamB; Provisional


Pssm-ID: 236857 [Multi-domain]  Cd Length: 394  Bit Score: 308.40  E-value: 2.63e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  44 AELVKFEPSVKVNKAWSVNLGKGERRIGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVWTW----EPQKEKKKPKLRL 119
Cdd:PRK11138  33 SPLPQVENQFTPTTVWSTSVGDGVGDYYSRLHPAVAYNKVYAADRAGLVKALDADTGKEIWSVdlseKDGWFSKNKSALL 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 120 SGGPGVGENLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAPAVAQGLVFVRSNDGRVTAFDAGNGTQKWFNPSELPA 199
Cdd:PRK11138 113 SGGVTVAGGKVYIGSEKGQVYALNAEDGEVAWQTKVAGEALSRPVVSDGLVLVHTSNGMLQALNESDGAVKWTVNLDVPS 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 200 LTVRG-NAPVVTGPGVlFIGKDEGAVAALAQQDGRTLWEQNIGNGEGRTELERMADVDGAPVLEGNTLYVSSFKNQTMAI 278
Cdd:PRK11138 193 LTLRGeSAPATAFGGA-IVGGDNGRVSAVLMEQGQLIWQQRISQPTGATEIDRLVDVDTTPVVVGGVVYALAYNGNLVAL 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 279 EGPTGRPLWARDHGGAGGVAVSSGNVFVTDNKGGVFGLDKATGAAMWSQTELARRSLTGPVLQGDYVVVGDYKGYVHWLK 358
Cdd:PRK11138 272 DLRSGQIVWKREYGSVNDFAVDGGRIYLVDQNDRVYALDTRGGVELWSQSDLLHRLLTAPVLYNGYLVVGDSEGYLHWIN 351

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 923065875 359 TSDGAMAARAKSGGDALLAQPVVADGVLLVQNVDGKLTAFRL 400
Cdd:PRK11138 352 REDGRFVAQQKVDSSGFLSEPVVADDKLLIQARDGTVYAITR 393
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 90-327 1.57e-54

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 180.29  E-value: 1.57e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875   90 GGVHAIDLQTGKKVWTwepqkekKKPKLRLSGGPGVGENLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAPAVAQGL 169
Cdd:pfam13360   3 GVVTALDAATGAELWR-------VDLETGLGGGVAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLGAPLVAGGR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  170 VFVRSNDGRVTAFDAGNGTQKWFNPSELPALTVRGNAPVVTGPGVLFIGKDEGAVAALAQQDGRTLWEQNIGNGEGRTEL 249
Cdd:pfam13360  76 VFVVAGDGSLIALDAADGRRLWSYQRSGEPLALRSSGSPAVVGDTVVAGFSSGKLVALDPATGKVRWEAPLAAPRGTNEL 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 923065875  250 ERMADVDGAPVLEGNTLYVSSFKNQTMAIEGPTGRPLWARDHGGAGGVAVSSGNVFVTDNKGGVFGLDKATGAAMWSQ 327
Cdd:pfam13360 156 ERLVDITGTPVVAGGRVFASAYQGRLVAFDAATGRRLWTREISGPNGPILDGDLLYVVSDDGELYALDRATGAVVWKT 233
PQQ smart00564
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline ...
 123-152 1.72e-03

beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.


Pssm-ID: 128836 [Multi-domain]  Cd Length: 33  Bit Score: 35.59  E-value: 1.72e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 923065875   123 PGVGENLVVIGTLDGQVIALDINDGSEKWR 152
Cdd:smart00564   2 VVLSDGTVYVGSTDGTLYALDAKTGEILWT 31
 
Name Accession Description Interval E-value
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 42-400 1.27e-153

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 438.48  E-value: 1.27e-153
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  42 EPAELVKFEPSVKVNKAWSVNLGKGERRIGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVWTwepqkekKKPKLRLSG 121
Cdd:COG1520   19 PPAPLPEFEPSVKVKQLWSASVGDGVGKGYSRLAPAVAGDRVYAADADGRVAALDAATGKELWR-------VDLGEPLSG 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 122 GPGVGENLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAPAVAQGLVFVRSNDGRVTAFDAGNGTQKWFNPSELPALT 201
Cdd:COG1520   92 GVGADGGLVVVGTEDGEVIALDADDGEELWRARLSSEVLAAPAVAGGRVVVRTGDGRVYALDAATGERLWSYQRPVPALT 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 202 VRGNAPVVTGPGVLFIGKDEGAVAALAQQDGRTLWEQNIGNGEGRTELERMADVDGAPVLEGNTLYVSSFKNQTMAIEGP 281
Cdd:COG1520  172 LRGTSSPVIVGGAVLVGFANGKLVALDLANGQPLWEQRVAQPRGRTELERLVDVDGTPVVDGGVVYAVAYQGRLAALDLR 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 282 TGRPLWARDHGGAGGVAVSSGNVFVTDNKGGVFGLDKATGAAMWSQTELARRSLTGPVLQGDYVVVGDYKGYVHWLKTSD 361
Cdd:COG1520  252 SGRVLWSRDLSSYTGLAVDGNNLYVTDDDGRVWALDRRNGAELWKQDALLYRGLTAPVVLGDYVVVGDFEGYLHWLSRDD 331

                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 923065875 362 GAMAARAKSGGDALLAQPVVADGVLLVQNVDGKLTAFRL 400
Cdd:COG1520  332 GSLVARLRVDGSGIRAAPVVVGDTLYVQTRDGTLAALRL 370
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 9-399 2.86e-143

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 412.40  E-value: 2.86e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875    9 RVATVLLMGMALTGCStvkgWFAGKDAAAkkaqEPAELVKFEPSVKVNKAWSVNLGKGERRIGVRQGPAVANGHVFAAAI 88
Cdd:TIGR03300   2 RLALVLACAALLSGCS----WFSSEDDEP----QPAELPEFQPTVKVDQVWSASVGDGVGHYYLRLQPAVAGGKVYAADA 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875   89 TGGVHAIDLQTGKKVWTwepqkekKKPKLRLSGGPGVGENLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAPAVAQG 168
Cdd:TIGR03300  74 DGTVAALDAETGKRLWR-------VDLDERLSGGVGADGGLVFVGTEKGEVIALDAEDGKELWRAKLSSEVLSPPLVANG 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  169 LVFVRSNDGRVTAFDAGNGTQKWFNPSELPALTVRGNAPVVTGPGVLFIGKDEGAVAALAQQDGRTLWEQNIGNGEGRTE 248
Cdd:TIGR03300 147 LVVVRTNDGRLTALDAATGERLWTYSRVTPPLTLRGSASPVIADGGVLVGFAGGKLVALDLQTGQPLWEQRVALPKGRTE 226

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  249 LERMADVDGAPVLEGNTLYVSSFKNQTMAIEGPTGRPLWARDHGGAGGVAVSSGNVFVTDNKGGVFGLDKATGAAMWSQT 328
Cdd:TIGR03300 227 LERLVDVDGDPVVDGGQVYAVSYQGRVAALDLRSGRVLWKRDASSYQGPAVDDNRLYVTDADGVVVALDRRSGSELWKND 306

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 923065875  329 ELARRSLTGPVLQGDYVVVGDYKGYVHWLKTSDGAMAARAKSGGDALLAQPVVADGVLLVQNVDGKLTAFR 399
Cdd:TIGR03300 307 ELKYRQLTAPAVLGGYLVVGDFEGYLHWLDRDDGSFVARLKTDGSGIASPPVVVGDGLLVQTRDGDLYAFR 377
BamB_YfgL cd10276
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ...
 42-400 4.06e-106

Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.


Pssm-ID: 199834 [Multi-domain]  Cd Length: 358  Bit Score: 316.97  E-value: 4.06e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  42 EPAELVKFEPSVKVNKAWSVNLGKGERRiGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVWtwepqKEKKKPKLRLSG 121
Cdd:cd10276    1 PPTDLPEPTPEFDPEVLWSKSVGNGGMA-GIDLTPVVAGDMVYAADANGQVSAFNATTGKIIW-----ETSLSGKGFLGG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 122 GPGVGENLVVIGTLDGQVIALDINDGSEKWRARVP-GEVIAAPAVAQGLVFVRSNDGRVTAFDAGNGTQKWFNPSELPAL 200
Cdd:cd10276   75 TPAVGNGKIFVGTESGYLYALDAKDGSELWRTEVSdSQLLSPPTYADGKIYVGTGDGRLYYCNAETGKVVWNRTSTAPEL 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 201 TVRGNAPVVTGPGVLFIGKDEGAVAALAQQDGRTLWEQNIGNGEGRTELERMADVDGAPVLEGNTLYVSSFKNQTMAIEG 280
Cdd:cd10276  155 SLRGGAAPVGAYDVVFVGDGNGTVVALNTGTGVDIWEFSVSEPRGRTELPRMIDSSVTYVVVGGYLYSTSYQGYLVALDF 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 281 PTGRPLWARDH-GGAGGVAVSSGNVFVTDNKGGVFGLDKATGAAMWSQTELARRSLTGPVL-QGDYVVVGDY-KGYVHWL 357
Cdd:cd10276  235 ESGQFLWSRKAsGGTSTSTDANGRVYVGDGEGSLYCLDASTGDELWSQTVLLGRVLSSPAIyVGVYIYVTDNaEGYLYCL 314

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 923065875 358 KTSDGAMAARAK-SGGDALLAQPVVADGVLLVQNVDGKLTAFRL 400
Cdd:cd10276  315 KDNDGLTVARVEvDYSQYILQGPAVSDGWLYYGTDDGYLYALTR 358
PRK11138 PRK11138
outer membrane biogenesis protein BamB; Provisional
 44-400 2.63e-102

outer membrane biogenesis protein BamB; Provisional


Pssm-ID: 236857 [Multi-domain]  Cd Length: 394  Bit Score: 308.40  E-value: 2.63e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  44 AELVKFEPSVKVNKAWSVNLGKGERRIGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVWTW----EPQKEKKKPKLRL 119
Cdd:PRK11138  33 SPLPQVENQFTPTTVWSTSVGDGVGDYYSRLHPAVAYNKVYAADRAGLVKALDADTGKEIWSVdlseKDGWFSKNKSALL 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 120 SGGPGVGENLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAPAVAQGLVFVRSNDGRVTAFDAGNGTQKWFNPSELPA 199
Cdd:PRK11138 113 SGGVTVAGGKVYIGSEKGQVYALNAEDGEVAWQTKVAGEALSRPVVSDGLVLVHTSNGMLQALNESDGAVKWTVNLDVPS 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 200 LTVRG-NAPVVTGPGVlFIGKDEGAVAALAQQDGRTLWEQNIGNGEGRTELERMADVDGAPVLEGNTLYVSSFKNQTMAI 278
Cdd:PRK11138 193 LTLRGeSAPATAFGGA-IVGGDNGRVSAVLMEQGQLIWQQRISQPTGATEIDRLVDVDTTPVVVGGVVYALAYNGNLVAL 271

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 279 EGPTGRPLWARDHGGAGGVAVSSGNVFVTDNKGGVFGLDKATGAAMWSQTELARRSLTGPVLQGDYVVVGDYKGYVHWLK 358
Cdd:PRK11138 272 DLRSGQIVWKREYGSVNDFAVDGGRIYLVDQNDRVYALDTRGGVELWSQSDLLHRLLTAPVLYNGYLVVGDSEGYLHWIN 351

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 923065875 359 TSDGAMAARAKSGGDALLAQPVVADGVLLVQNVDGKLTAFRL 400
Cdd:PRK11138 352 REDGRFVAQQKVDSSGFLSEPVVADDKLLIQARDGTVYAITR 393
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 90-327 1.57e-54

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 180.29  E-value: 1.57e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875   90 GGVHAIDLQTGKKVWTwepqkekKKPKLRLSGGPGVGENLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAPAVAQGL 169
Cdd:pfam13360   3 GVVTALDAATGAELWR-------VDLETGLGGGVAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLGAPLVAGGR 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  170 VFVRSNDGRVTAFDAGNGTQKWFNPSELPALTVRGNAPVVTGPGVLFIGKDEGAVAALAQQDGRTLWEQNIGNGEGRTEL 249
Cdd:pfam13360  76 VFVVAGDGSLIALDAADGRRLWSYQRSGEPLALRSSGSPAVVGDTVVAGFSSGKLVALDPATGKVRWEAPLAAPRGTNEL 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 923065875  250 ERMADVDGAPVLEGNTLYVSSFKNQTMAIEGPTGRPLWARDHGGAGGVAVSSGNVFVTDNKGGVFGLDKATGAAMWSQ 327
Cdd:pfam13360 156 ERLVDITGTPVVAGGRVFASAYQGRLVAFDAATGRRLWTREISGPNGPILDGDLLYVVSDDGELYALDRATGAVVWKT 233
PQQ_DH_like cd00216
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases ...
 58-383 9.55e-19

PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases with pyrroloquinoline quinone (PQQ) as a cofactor, such as ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller, and the family also includes distantly related proteins which are not enzymatically active and do not bind PQQ.


Pssm-ID: 199833 [Multi-domain]  Cd Length: 434  Bit Score: 87.66  E-value: 9.55e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  58 AWSVNLGKGERRiGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVWTWEPQKEKKKPKLR---LSGGPGVGENLVVIGT 134
Cdd:cd00216   10 AWSFSTGDGGNR-GSELTPIVVDGVMYATTSFSRVFALDADDGKEIWSYDPALKDGWFEACcdlVNRGVAVWGGKVYIGV 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 135 LDGQVIALDINDGSEKWRARV-----PGEVIAAPAVAQGLVFVRSND------GRVTAFDAGNGTQKW-FNPSE-----L 197
Cdd:cd00216   89 LDGRVYALNAETGKVAWKVKNadvlgGYTATSAPVVVDGLVIIGSSGdefgvrGYLTAYDVATGEEKWrFYLVMpdpnlL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 198 PA--------------------LTVRGNAPVVTGP--GVLFIGKDEGA------------------VAALAQQDGRTLWE 237
Cdd:cd00216  169 PGkdstvtdrntptgdehtwtsGGGTGWSSAAYDAelNLIYVGGGNPTpwnwggnrtpgdnlytssIVAVNADTGEMKWQ 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 238 QNIGNGEGRTelermADVDGAPVLEGNT--------LYVSSFKNQTMAIEGPTGRPLWARdhgGAGGVAVSSGN-VFVTD 308
Cdd:cd00216  249 YQTTPHDAWD-----YDGDNTPVLADIKvkgkkvkvLFAPAKNGNFYVLDRRNGELVSAR---PLVPDSYDPDReLFYVP 320

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 923065875 309 NKGGVFGLDKATGAAMWSQTELARrSLTGPVL-QGDYVVVGDYKGYVHWLKTSDGAMAARAKSGGDAlLAQPVVAD 383
Cdd:cd00216  321 ANGRIMALDPVTGVVVWEKSELHP-LLGGPLStAGNLVFVGTSDGYLKAYNADTGEKLWQQKVPSGF-QAEPVTYE 394
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 220-402 1.46e-15

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 75.52  E-value: 1.46e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  220 DEGAVAALAQQDGRTLWEQNIGNGEGrtelermadvdGAPVLEGNTLYVSSFKNQTMAIEGPTGRPLWARDHGGAGGVA- 298
Cdd:pfam13360   1 ADGVVTALDAATGAELWRVDLETGLG-----------GGVAVDGGRLFVATGGGQLVALDAATGKLLWRQTLSGEVLGAp 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  299 -VSSGNVFVTDNKGGVFGLDKATGAAMWSQTE----LARRSLTGPVLQGDYVVVGDYKGYVHWLKTSDG----------A 363
Cdd:pfam13360  70 lVAGGRVFVVAGDGSLIALDAADGRRLWSYQRsgepLALRSSGSPAVVGDTVVAGFSSGKLVALDPATGkvrweaplaaP 149

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 923065875  364 MAARAKSGGDALLAQPVVADGVLLVQNVDGKLTAFRLAN 402
Cdd:pfam13360 150 RGTNELERLVDITGTPVVAGGRVFASAYQGRLVAFDAAT 188
Gcd COG4993
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
58-191 1.64e-14

Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];


Pssm-ID: 444017 [Multi-domain]  Cd Length: 515  Bit Score: 74.81  E-value: 1.64e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  58 AWSVNLGkGERRIGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVWTWEPQKEKKKPKLRLSG-GPGVGENLVVIGTLD 136
Cdd:COG4993   34 AWTFSTG-DLPERGHEATPLVVDGVLYVCTPHNRVFALDAATGKELWRYDPKLPDDAACCDVVNrGVAYYDGRIFLGTLD 112

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 923065875 137 GQVIALDINDGSEKWRARV----PGEVI-AAPAVAQGLVFV--RSND----GRVTAFDAGNGTQKW 191
Cdd:COG4993  113 GRLVALDAKTGKVCWDVKVgdpkKGYTItSAPLVVKDKVIVggSGGEfgprGVVRAYDARTGKLVW 178
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
 284-402 2.04e-14

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 74.08  E-value: 2.04e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 284 RPLWARDHGGAGG-------VAVSSGNVFVTDNKGGVFGLDKATGAAMWsQTELARRSLTGPVLQGDYVVVGDYKGYVHW 356
Cdd:COG1520   33 KQLWSASVGDGVGkgysrlaPAVAGDRVYAADADGRVAALDAATGKELW-RVDLGEPLSGGVGADGGLVVVGTEDGEVIA 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 923065875 357 LKTSDGAMAARAKSGGDALlAQPVVADGVLLVQNVDGKLTAFRLAN 402
Cdd:COG1520  112 LDADDGEELWRARLSSEVL-AAPAVAGGRVVVRTGDGRVYALDAAT 156
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
 282-402 2.70e-14

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 73.81  E-value: 2.70e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  282 TGRPLWARDHGGAGG-------VAVSSGNVFVTDNKGGVFGLDKATGAAMWsQTELARRSLTGPVLQGDYVVVGDYKGYV 354
Cdd:TIGR03300  39 KVDQVWSASVGDGVGhyylrlqPAVAGGKVYAADADGTVAALDAETGKRLW-RVDLDERLSGGVGADGGLVFVGTEKGEV 117

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 923065875  355 HWLKTSDGAMAARAKSGGDALlAQPVVADGVLLVQNVDGKLTAFRLAN 402
Cdd:TIGR03300 118 IALDAEDGKELWRAKLSSEVL-SPPLVANGLVVVRTNDGRLTALDAAT 164
PQQ_ADH_II cd10279
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of ...
 58-191 8.32e-12

PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of monomeric and soluble type II alcohol dehydrogenases utilizes pyrroloquinoline quinone (PQQ) as a cofactor and is related to ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller.


Pssm-ID: 199837 [Multi-domain]  Cd Length: 549  Bit Score: 66.51  E-value: 8.32e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  58 AWSVNLgkgERRIGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVWTWEPQKEKKKPKL----RLSGGPGVGENLVVIG 133
Cdd:cd10279   32 AWYFDL---DTNRGQEATPLVVDGVMYVSGPWSVVYALDARTGKLLWQYDPEVDRESGRKaccdVVNRGVAVWDGKVFVG 108

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 923065875 134 TLDGQVIALDINDGSEKWRAR-VPGE----VIAAPAVAQGLVFVRSND------GRVTAFDAGNGTQKW 191
Cdd:cd10279  109 TLDGRLIALDAKTGKEVWSVDtIDPRkpytITGAPRVAKGKVVIGNGGaefgvrGYVSAYDAETGKLVW 177
PQQ_ADH_I cd10277
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ...
 58-191 1.06e-11

Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.


Pssm-ID: 199835 [Multi-domain]  Cd Length: 529  Bit Score: 66.17  E-value: 1.06e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  58 AWSVNLGKGERriGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVWTWepqKEKKKPKLRLSGGP---GVG--ENLVVI 132
Cdd:cd10277   40 AWSFSFGGKQR--GQESQPIVNDGVMYVTTSYNRVFAIDAKTGKELWKY---KHRLPEDIRPCCDVvnrGVAlyGDKVYF 114

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 133 GTLDGQVIALDINDGSEKWRARV----PGEVI-AAPAVAQGLVFVRS------NDGRVTAFDAGNGTQKW 191
Cdd:cd10277  115 GTLDAHLVALDAKTGKVVWKKKVadykAGYSMtLAPLVVKGKVIVGVsggefgVRGFIAALDAETGKEVW 184
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 56-191 4.81e-09

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 56.26  E-value: 4.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875   56 NKAWSVNLGKGERRIGVRQGPAVANGHVFAAAITGGVHAIDLQTGKKVW----TWEPQKEKKKPKLRLSGGPGVGENLVV 131
Cdd:pfam13360  94 RRLWSYQRSGEPLALRSSGSPAVVGDTVVAGFSSGKLVALDPATGKVRWeaplAAPRGTNELERLVDITGTPVVAGGRVF 173

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  132 IGTLDGQVIALDINDGSEKWRARVPGevIAAPAVAQGLVFVRSNDGRVTAFDAGNGTQKW 191
Cdd:pfam13360 174 ASAYQGRLVAFDAATGRRLWTREISG--PNGPILDGDLLYVVSDDGELYALDRATGAVVW 231
Gcd COG4993
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
89-165 3.51e-07

Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];


Pssm-ID: 444017 [Multi-domain]  Cd Length: 515  Bit Score: 52.08  E-value: 3.51e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 923065875  89 TGGVHAIDLQTGKKVWTWEPQKEkkkpklrLSGGPGV-GENLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAPAV 165
Cdd:COG4993  408 WGTLTAIDLNTGKIVWQVPLGFP-------NWGGPLAtAGGLVFIGTLDGYLRAFDAKTGKELWKFRLPSGGQATPMT 478
PQQ_MDH cd10278
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ...
 122-191 1.12e-06

Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.


Pssm-ID: 199836 [Multi-domain]  Cd Length: 553  Bit Score: 50.40  E-value: 1.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 122 GPGVGENLVVIGTLDGQVIALDINDGSEKWRARVP----GEVI-AAPAVAQGLVFVRSND------GRVTAFDAGNGTQK 190
Cdd:cd10278   97 GLAYADGKIFFNQLDGHLVALDAKTGKEVWKVKNGdpkvGETLtMAPLVVKDKVIVGISGgefgvrGYVTAYDLKTGKLV 176


                 .
gi 923065875 191 W 191
Cdd:cd10278  177 W 177
PQQ_ADH_II cd10279
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of ...
 248-367 1.69e-06

PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of monomeric and soluble type II alcohol dehydrogenases utilizes pyrroloquinoline quinone (PQQ) as a cofactor and is related to ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller.


Pssm-ID: 199837 [Multi-domain]  Cd Length: 549  Bit Score: 49.95  E-value: 1.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 248 ELERMADVDGAPVLEGNTLYVSSFKNQTMAIEGPTGRPLWA------RDHGGAG-------GVAVSSGNVFVTDNKGGVF 314
Cdd:cd10279   36 DLDTNRGQEATPLVVDGVMYVSGPWSVVYALDARTGKLLWQydpevdRESGRKAccdvvnrGVAVWDGKVFVGTLDGRLI 115

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 923065875 315 GLDKATGAAMWS-QTELARRSLT---GPVLQGDYVVVG----DY--KGYVHWLKTSDGAMAAR 367
Cdd:cd10279  116 ALDAKTGKEVWSvDTIDPRKPYTitgAPRVAKGKVVIGnggaEFgvRGYVSAYDAETGKLVWR 178
PQQ pfam01011
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ...
 128-163 6.85e-06

PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.


Pssm-ID: 395799 [Multi-domain]  Cd Length: 36  Bit Score: 42.56  E-value: 6.85e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 923065875  128 NLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAP 163
Cdd:pfam01011   1 GTVYLGSDDGYLYALDAETGKVLWSFKTGGAVLSSP 36
PQQ_ADH_I cd10277
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ...
 256-328 8.99e-06

Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.


Pssm-ID: 199835 [Multi-domain]  Cd Length: 529  Bit Score: 47.68  E-value: 8.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 256 DGAPVLEGNTLYVSSFKNQTMAIEGPTGRPLWARDH---GGAG--------GVAVSSGNVFVTDNKGGVFGLDKATGAAM 324
Cdd:cd10277   53 ESQPIVNDGVMYVTTSYNRVFAIDAKTGKELWKYKHrlpEDIRpccdvvnrGVALYGDKVYFGTLDAHLVALDAKTGKVV 132


                 ....
gi 923065875 325 WSQT 328
Cdd:cd10277  133 WKKK 136
PQQ_ADH_II cd10279
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of ...
 72-152 1.98e-05

PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of monomeric and soluble type II alcohol dehydrogenases utilizes pyrroloquinoline quinone (PQQ) as a cofactor and is related to ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller.


Pssm-ID: 199837 [Multi-domain]  Cd Length: 549  Bit Score: 46.48  E-value: 1.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  72 VRQGPAVANGHVFAAAITGGVHAIDLQTGKKVwtWEPQKEKKKPKLRLSGGPGVGENLVVIGT------LDGQVIALDIN 145
Cdd:cd10279   94 VNRGVAVWDGKVFVGTLDGRLIALDAKTGKEV--WSVDTIDPRKPYTITGAPRVAKGKVVIGNggaefgVRGYVSAYDAE 171


                 ....*..
gi 923065875 146 DGSEKWR 152
Cdd:cd10279  172 TGKLVWR 178
Gcd COG4993
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
137-191 1.99e-05

Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];


Pssm-ID: 444017 [Multi-domain]  Cd Length: 515  Bit Score: 46.69  E-value: 1.99e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 923065875 137 GQVIALDINDGSEKWRARVPGEVIAAPAV-AQGLVFVRSNDGRVTAFDAGNGTQKW 191
Cdd:COG4993  409 GTLTAIDLNTGKIVWQVPLGFPNWGGPLAtAGGLVFIGTLDGYLRAFDAKTGKELW 464
PQQ_ADH_I cd10277
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ...
 89-163 2.31e-05

Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.


Pssm-ID: 199835 [Multi-domain]  Cd Length: 529  Bit Score: 46.52  E-value: 2.31e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 923065875  89 TGGVHAIDLQTGKKVWTWEPQKEKKKPKLRLSGGpgvgenLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAP 163
Cdd:cd10277  415 IGELQAIDPTTGKKVWEHKTPLPLWGGVLTTAGG------LVFTGTPDGYFRAFDAKTGKELWEFQTGSGIIGPP 483
Gcd COG4993
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
177-243 2.50e-05

Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];


Pssm-ID: 444017 [Multi-domain]  Cd Length: 515  Bit Score: 46.30  E-value: 2.50e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 923065875 177 GRVTAFDAGNGTQKWFNPSELPALTvrgnAPVVTGPGVLFIGKDEGAVAALAQQDGRTLWEQNIGNG 243
Cdd:COG4993  409 GTLTAIDLNTGKIVWQVPLGFPNWG----GPLATAGGLVFIGTLDGYLRAFDAKTGKELWKFRLPSG 471
PQQ_3 pfam13570
PQQ-like domain;
147-182 2.69e-05

PQQ-like domain;


Pssm-ID: 463925 [Multi-domain]  Cd Length: 36  Bit Score: 41.03  E-value: 2.69e-05
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 923065875  147 GSEKWRARVPGEVIAAPAVAQGLVFVRSNDGRVTAF 182
Cdd:pfam13570   1 GEVLWRFETGGPIVSSPAVAGGLVYVGTGDGTLYAL 36
PQQ_ADH_I cd10277
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ...
 177-243 9.37e-05

Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.


Pssm-ID: 199835 [Multi-domain]  Cd Length: 529  Bit Score: 44.60  E-value: 9.37e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 923065875 177 GRVTAFDAGNGTQKWFNPSELPAltvrgNAPVV-TGPGVLFIGKDEGAVAALAQQDGRTLWEQNIGNG 243
Cdd:cd10277  416 GELQAIDPTTGKKVWEHKTPLPL-----WGGVLtTAGGLVFTGTPDGYFRAFDAKTGKELWEFQTGSG 478
PQQ_MDH cd10278
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ...
 72-153 2.66e-04

Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.


Pssm-ID: 199836 [Multi-domain]  Cd Length: 553  Bit Score: 43.08  E-value: 2.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  72 VRQGPAVANGHVFAAAITGGVHAIDLQTGKKVwtWEPQKEKKKPKLRLSGGPGVGENLVVIGT------LDGQVIALDIN 145
Cdd:cd10278   94 VNRGLAYADGKIFFNQLDGHLVALDAKTGKEV--WKVKNGDPKVGETLTMAPLVVKDKVIVGIsggefgVRGYVTAYDLK 171


                 ....*...
gi 923065875 146 DGSEKWRA 153
Cdd:cd10278  172 TGKLVWRA 179
PQQ_MDH cd10278
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ...
 257-372 3.55e-04

Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.


Pssm-ID: 199836 [Multi-domain]  Cd Length: 553  Bit Score: 42.70  E-value: 3.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875 257 GAPVLEGNTLYV-SSFKNQTMAIE-GPTGRPLWA---RDHGGAGGVAV----------SSGNVFVTDNKGGVFGLDKATG 321
Cdd:cd10278   43 GAPLVVGDTMYVvTPFPNNVYALDlNDPGKILWKykpKQDPSAVAVACcdvvnrglayADGKIFFNQLDGHLVALDAKTG 122

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 923065875 322 AAMWSqTELAR----RSLTG-PVLQGDYVVVGD------YKGYVHWLKTSDGAMAARAKSGG 372
Cdd:cd10278  123 KEVWK-VKNGDpkvgETLTMaPLVVKDKVIVGIsggefgVRGYVTAYDLKTGKLVWRAYSTG 183
PQQ_MDH cd10278
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ...
 89-163 7.52e-04

Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.


Pssm-ID: 199836 [Multi-domain]  Cd Length: 553  Bit Score: 41.54  E-value: 7.52e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 923065875  89 TGGVHAIDLQTGKKVWTWEPQKEKKKPKLRLSGGpgvgenLVVIGTLDGQVIALDINDGSEKWRARVPGEVIAAP 163
Cdd:cd10278  425 MGQFKAWDPVTGKTKWEIKERFPVWSGTLATAGG------LVFYGTLDGWFKAVDAKTGKLLWKFKLPSGIIGNP 493
PQQ smart00564
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline ...
 123-152 1.72e-03

beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.


Pssm-ID: 128836 [Multi-domain]  Cd Length: 33  Bit Score: 35.59  E-value: 1.72e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 923065875   123 PGVGENLVVIGTLDGQVIALDINDGSEKWR 152
Cdd:smart00564   2 VVLSDGTVYVGSTDGTLYALDAKTGEILWT 31
PQQ smart00564
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline ...
 76-105 2.42e-03

beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.


Pssm-ID: 128836 [Multi-domain]  Cd Length: 33  Bit Score: 35.20  E-value: 2.42e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 923065875    76 PAVANGHVFAAAITGGVHAIDLQTGKKVWT 105
Cdd:smart00564   2 VVLSDGTVYVGSTDGTLYALDAKTGEILWT 31
PQQ_mGDH cd10280
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes ...
 90-168 2.65e-03

Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes belongs to the dehydrogenase family with pyrroloquinoline quinone (PQQ) as cofactor, and is the only subfamily that is bound to the membrane. Glucose dehydrogenase converts D-glucose to D-glucono-1,5-lactone in a reaction that is coupled with the respiratory chain in the periplasmic oxidation of sugars and alcohols in gram-negative bacteria. Ubiquinone functions as the electron acceptor. The alignment model contains an 8-bladed beta-propeller.


Pssm-ID: 199838 [Multi-domain]  Cd Length: 616  Bit Score: 39.87  E-value: 2.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 923065875  90 GGVHAIDLQTGKKVW-----TWEPQKEKKKPKLRLSGGPGVG------ENLVVIG-TLDGQVIALDINDGSEKWRARVPG 157
Cdd:cd10280  497 GTLTAIDLNTGKILWqvplgTVPDLGPKGIPLPIPTGTPNLGgpvvtaGGLVFIAaTQDNYLRAFDKATGKELWEARLPA 576

                         90
                 ....*....|.
gi 923065875 158 EVIAAPAVAQG 168
Cdd:cd10280  577 GGQATPMTYEV 587
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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