|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-1038 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1301.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 1 MPKFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSS 80
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 81 SSASNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVVAKANAGFLMVVALQSDTPTINRDALNDIVGS 160
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 161 RVLDQVSRIPGVGSTQQFGSEYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALGSDPSPEGQHFTATVSAEGRF 240
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 241 SSPQEFENIILRANADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPAG 320
Cdd:TIGR00915 241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 321 VTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVL 400
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 401 AIGIVVDDAIVVIENVERIMTEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMAF 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 481 SAFLALGFTPALCATFLKP----THNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHAPRWMILFVVLTALCGFLFTRMP 556
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPiekgEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 557 GSFLPEEDQGYALAIVQLPPGSTKGQTNEVFAQMRGILEKQDG--YEGMLQVAGFSFVGSGENVGMGFIRLKPWEERKF- 633
Cdd:TIGR00915 561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKanVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGk 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 634 --TAPEFIQNMNGAFYGIKEAQIFVVNLPTVQGLGQFGGFDMWLQDRSGAGYEQLTQARNILLGQAAQKPDhLVGVRPNG 711
Cdd:TIGR00915 641 enSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPA-LTRVRPNG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 712 LENAPQLQLHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYSPssltqNAD 791
Cdd:TIGR00915 720 LEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVR-----NAS 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 792 GTnaMIPLNTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIVnDDLPAGFGYDWSGMSYQEILAGNA 871
Cdd:TIGR00915 795 GE--MVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIA-QKLPPGFGFSWTGMSYEERLSGSQ 871
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 872 ATLLLVLSIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVEQ 951
Cdd:TIGR00915 872 APALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKEL 951
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 952 RAAGKNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVRRML 1031
Cdd:TIGR00915 952 MAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLF 1031
|
....*..
gi 924469094 1032 GDKLDEP 1038
Cdd:TIGR00915 1032 KRKAHEK 1038
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1030 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1165.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 1 MPKFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSS 80
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 81 SSaSNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVVAKANAGFLMVVALQSDTptINRDALNDIVGS 160
Cdd:COG0841 83 TS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 161 RVLDQVSRIPGVGSTQQFGS-EYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALGsdpspeGQHFTATVSAEGR 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGrEREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIG------GGDREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 240 FSSPQEFENIILRANaDGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPA 319
Cdd:COG0841 234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 320 GVTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMV 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 400 LAIGIVVDDAIVVIENVERIMtEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMA 479
Cdd:COG0841 393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 480 FSAFLALGFTPALCATFLKPTHNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHAPRWMILFVVLTALCGFLFTRMPGSF 559
Cdd:COG0841 472 ISLFVALTLTPALCARLLKPHPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEF 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 560 LPEEDQGYALAIVQLPPGSTKGQTNEVFAQMRGILEKQDGYEGMLQVAGFSFVGSGENVGMGFIRLKPWEERKFTAPEFI 639
Cdd:COG0841 552 FPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDRSADEII 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 640 QNMNGAFYGIKEAQIFVVNLPTvQGLGQFGGFDMWLQdrsGAGYEQLTQARNILLGQAAQKPdHLVGVRPNGLENAPQLQ 719
Cdd:COG0841 632 ARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIP-GLVDVRSDLQLGKPELQ 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 720 LHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYspsslTQNADGtnAMIPL 799
Cdd:COG0841 707 LDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLY-----VRTPDG--EMVPL 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 800 NTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIVND-DLPAGFGYDWSGMSYQEILAGNAATLLLVL 878
Cdd:COG0841 780 SSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElKLPPGVSIEFTGQAEEEQESFSSLGLAFLL 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 879 SIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVEQRAAGKNL 958
Cdd:COG0841 860 ALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSL 939
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 924469094 959 RDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVRRM 1030
Cdd:COG0841 940 REAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRL 1011
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-1037 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 1137.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 1 MPKFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSS 80
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 81 SSASNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVVAKANAGFLMVVALQSDTPTINRDALNDIVGS 160
Cdd:PRK15127 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 161 RVLDQVSRIPGVGSTQQFGSEYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALGSDPSPEGQHFTATVSAEGRF 240
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 241 SSPQEFENIILRANADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPAG 320
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 321 VTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVL 400
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 401 AIGIVVDDAIVVIENVERIMTEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMAF 480
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 481 SAFLALGFTPALCATFLKPT----HNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHAPRWMILFVVLTALCGFLFTRMP 556
Cdd:PRK15127 481 SVLVALILTPALCATMLKPIakgdHGEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 557 GSFLPEEDQGYALAIVQLPPGSTKGQTNEVFAQMRG--ILEKQDGYEGMLQVAGFSFVGSGENVGMGFIRLKPWEERKFT 634
Cdd:PRK15127 561 SSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDyyLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 635 A---PEFIQNMNGAFYGIKEAQIFVVNLPTVQGLGQFGGFDMWLQDRSGAGYEQLTQARNILLGQAAQKPDHLVGVRPNG 711
Cdd:PRK15127 641 EnkvEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDMLVGVRPNG 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 712 LENAPQLQLHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYspsslTQNAD 791
Cdd:PRK15127 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWY-----VRAAD 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 792 GTnaMIPLNTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIVNdDLPAGFGYDWSGMSYQEILAGNA 871
Cdd:PRK15127 796 GQ--MVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELAS-KLPTGVGYDWTGMSYQERLSGNQ 872
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 872 ATLLLVLSIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVE- 950
Cdd:PRK15127 873 APALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDl 952
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 951 QRAAGKNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVRRM 1030
Cdd:PRK15127 953 MDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRR 1032
|
....*..
gi 924469094 1031 LGDKLDE 1037
Cdd:PRK15127 1033 FSRKNED 1039
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1028 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1074.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 1 MPKFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSS 80
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 81 SSaSNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVVAKANAGFLMVVALQSDTPTINRDALNDIVGS 160
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 161 RVLDQVSRIPGVGSTQQFG-SEYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALgsdpspEGQHFTATVSAEGR 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGgSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 240 FSSPQEFENIILRaNADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPA 319
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 320 GVTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMV 399
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 400 LAIGIVVDDAIVVIENVERIMTEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMA 479
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 480 FSAFLALGFTPALCATFLKPTHNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHAPRWMILFVVLTALCGFLFTRMPGSF 559
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKHGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEF 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 560 LPEEDQGYALAIVQLPPGSTKGQTNEVFAQMRGILEKQDGYEGMLQVAGFSFVG--SGENVGMGFIRLKPWEERKF---T 634
Cdd:pfam00873 553 LPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKERPGpekS 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 635 APEFIQNMNGAFYGIKEAQIFVVNLPTVQGLGQFGGFDMWLQD-RSGAGYEQLTQARNILLGQAAQKPDhLVGVRPNGLE 713
Cdd:pfam00873 633 VQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG-LSDVRSDGQE 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 714 NAPQLQLHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYSPssltqNADGT 793
Cdd:pfam00873 712 DQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVR-----NPYGK 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 794 naMIPLNTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIV-NDDLPAGFGYDWSGMSYQEILAGNAA 872
Cdd:pfam00873 787 --MIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAkQVKLPPGYGYTWTGQFEQEQLAGNSL 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 873 TLLLVLSIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVEQR 952
Cdd:pfam00873 865 PILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELR 944
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 924469094 953 AA-GKNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVR 1028
Cdd:pfam00873 945 EQeGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-1029 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 728.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 5 FIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSSSSaS 84
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS-S 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 85 NGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQgVVVAKANAG--FLMVVALQSDTptINRDALNDIVGSRV 162
Cdd:NF033617 83 LGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDP-PVYRKANSAdtPIMYIGLTSEE--MPRGQLTDYAERVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 163 LDQVSRIPGVGSTQQFGSEY-AMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALgsdpspEGQHFTATVSAEGRFS 241
Cdd:NF033617 160 APKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAV------RGDSVVSTVRANDQLK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 242 SPQEFENIILRANADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPAGV 321
Cdd:NF033617 234 TAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNI 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 322 TWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVLA 401
Cdd:NF033617 314 KVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 402 IGIVVDDAIVVIENVERIMtEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMAFS 481
Cdd:NF033617 394 IGLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIIS 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 482 AFLALGFTPALCATFLKptHNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHaPRWMILFVVLT-ALCGFLFTRMPGSFL 560
Cdd:NF033617 473 GIVALTLTPMMCSRLLK--ANEKPGRFARAVDRFFDGLTARYGRGLKWVLKH-RPLTLVVALATlALLPLLYVFIPKELA 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 561 PEEDQGYALAIVQLPPGSTKGQTNEVFAQMRGILEKQDGYEgmlQVAGFSFVGS--GENVGMGFIRLKPWEERKFTAPEF 638
Cdd:NF033617 550 PSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQ---SLTSFNGVGGnpGDNTGFGIINLKPWDERDVSAQEI 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 639 IQNMNGAFYGIKEAQIFVVNLPTVQGLGQfGGFDMWLQDRSGAGYEQLTQARNILLGQAAQKPdHLVGVRPNGLENAPQL 718
Cdd:NF033617 627 IDRLRPKLAKVPGMDLFLFPLQDLPGGAG-SSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSP-QFADVDSDLQDKGPEL 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 719 QLHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYSPSSltqnaDGTnaMIP 798
Cdd:NF033617 705 NVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSN-----DGK--LVP 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 799 LNTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIVNDDLPAGFGYDWSGMSYQEILAGNAATLLLVL 878
Cdd:NF033617 778 LSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGSSLLFLFLL 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 879 SIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVE-QRAAGKN 957
Cdd:NF033617 858 ALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANElQRHQGLS 937
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 924469094 958 LRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVRR 1029
Cdd:NF033617 938 RREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
331-486 |
1.51e-03 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 42.84 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 331 TFVKISIQEV--VKTLfeavfLVFLVMLIFLQNFRATLIPTLVIPVALLGTFlgMWMIGFTINQLTLF------------ 396
Cdd:NF037998 426 TFKVNGISEFnpVVTL-----LMLIASIIFLLILAIAIMIYLLFAYRLLGLF--AIIIALTSISLTLYsptwfglaigpe 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 397 ---AMVLAIGIVVDDAIVVIENVERIMTEEGLAPKPATQKAMTQITGAVVAITVVLaavFIPS-ALQGGAAGEIyKQFAL 472
Cdd:NF037998 499 sitAIFIAIGLVLESCSLLFEAFKKHLYKNKRSIEESFKIANKETIGIIVDALVVL---LIPNlSLFWIGSNSI-KSFAT 574
|
170
....*....|....
gi 924469094 473 TIAISMAFSAFLAL 486
Cdd:NF037998 575 ILLVGVIISLVLVI 588
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-1038 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1301.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 1 MPKFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSS 80
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 81 SSASNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVVAKANAGFLMVVALQSDTPTINRDALNDIVGS 160
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 161 RVLDQVSRIPGVGSTQQFGSEYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALGSDPSPEGQHFTATVSAEGRF 240
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 241 SSPQEFENIILRANADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPAG 320
Cdd:TIGR00915 241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 321 VTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVL 400
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 401 AIGIVVDDAIVVIENVERIMTEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMAF 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 481 SAFLALGFTPALCATFLKP----THNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHAPRWMILFVVLTALCGFLFTRMP 556
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPiekgEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 557 GSFLPEEDQGYALAIVQLPPGSTKGQTNEVFAQMRGILEKQDG--YEGMLQVAGFSFVGSGENVGMGFIRLKPWEERKF- 633
Cdd:TIGR00915 561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKanVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGk 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 634 --TAPEFIQNMNGAFYGIKEAQIFVVNLPTVQGLGQFGGFDMWLQDRSGAGYEQLTQARNILLGQAAQKPDhLVGVRPNG 711
Cdd:TIGR00915 641 enSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPA-LTRVRPNG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 712 LENAPQLQLHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYSPssltqNAD 791
Cdd:TIGR00915 720 LEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVR-----NAS 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 792 GTnaMIPLNTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIVnDDLPAGFGYDWSGMSYQEILAGNA 871
Cdd:TIGR00915 795 GE--MVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIA-QKLPPGFGFSWTGMSYEERLSGSQ 871
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 872 ATLLLVLSIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVEQ 951
Cdd:TIGR00915 872 APALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKEL 951
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 952 RAAGKNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVRRML 1031
Cdd:TIGR00915 952 MAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLF 1031
|
....*..
gi 924469094 1032 GDKLDEP 1038
Cdd:TIGR00915 1032 KRKAHEK 1038
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1030 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1165.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 1 MPKFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSS 80
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 81 SSaSNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVVAKANAGFLMVVALQSDTptINRDALNDIVGS 160
Cdd:COG0841 83 TS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 161 RVLDQVSRIPGVGSTQQFGS-EYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALGsdpspeGQHFTATVSAEGR 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGrEREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIG------GGDREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 240 FSSPQEFENIILRANaDGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPA 319
Cdd:COG0841 234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 320 GVTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMV 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 400 LAIGIVVDDAIVVIENVERIMtEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMA 479
Cdd:COG0841 393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 480 FSAFLALGFTPALCATFLKPTHNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHAPRWMILFVVLTALCGFLFTRMPGSF 559
Cdd:COG0841 472 ISLFVALTLTPALCARLLKPHPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEF 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 560 LPEEDQGYALAIVQLPPGSTKGQTNEVFAQMRGILEKQDGYEGMLQVAGFSFVGSGENVGMGFIRLKPWEERKFTAPEFI 639
Cdd:COG0841 552 FPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDRSADEII 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 640 QNMNGAFYGIKEAQIFVVNLPTvQGLGQFGGFDMWLQdrsGAGYEQLTQARNILLGQAAQKPdHLVGVRPNGLENAPQLQ 719
Cdd:COG0841 632 ARLREKLAKIPGARVFVFQPPA-GGLGSGAPIEVQLQ---GDDLEELAAAAEKLLAALRQIP-GLVDVRSDLQLGKPELQ 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 720 LHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYspsslTQNADGtnAMIPL 799
Cdd:COG0841 707 LDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLY-----VRTPDG--EMVPL 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 800 NTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIVND-DLPAGFGYDWSGMSYQEILAGNAATLLLVL 878
Cdd:COG0841 780 SSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElKLPPGVSIEFTGQAEEEQESFSSLGLAFLL 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 879 SIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVEQRAAGKNL 958
Cdd:COG0841 860 ALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGMSL 939
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 924469094 959 RDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVRRM 1030
Cdd:COG0841 940 REAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRL 1011
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-1037 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 1137.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 1 MPKFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSS 80
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 81 SSASNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVVAKANAGFLMVVALQSDTPTINRDALNDIVGS 160
Cdd:PRK15127 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 161 RVLDQVSRIPGVGSTQQFGSEYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALGSDPSPEGQHFTATVSAEGRF 240
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 241 SSPQEFENIILRANADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPAG 320
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 321 VTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVL 400
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 401 AIGIVVDDAIVVIENVERIMTEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMAF 480
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 481 SAFLALGFTPALCATFLKPT----HNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHAPRWMILFVVLTALCGFLFTRMP 556
Cdd:PRK15127 481 SVLVALILTPALCATMLKPIakgdHGEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 557 GSFLPEEDQGYALAIVQLPPGSTKGQTNEVFAQMRG--ILEKQDGYEGMLQVAGFSFVGSGENVGMGFIRLKPWEERKFT 634
Cdd:PRK15127 561 SSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDyyLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 635 A---PEFIQNMNGAFYGIKEAQIFVVNLPTVQGLGQFGGFDMWLQDRSGAGYEQLTQARNILLGQAAQKPDHLVGVRPNG 711
Cdd:PRK15127 641 EnkvEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDMLVGVRPNG 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 712 LENAPQLQLHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYspsslTQNAD 791
Cdd:PRK15127 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWY-----VRAAD 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 792 GTnaMIPLNTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIVNdDLPAGFGYDWSGMSYQEILAGNA 871
Cdd:PRK15127 796 GQ--MVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELAS-KLPTGVGYDWTGMSYQERLSGNQ 872
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 872 ATLLLVLSIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVE- 950
Cdd:PRK15127 873 APALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDl 952
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 951 QRAAGKNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVRRM 1030
Cdd:PRK15127 953 MDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRR 1032
|
....*..
gi 924469094 1031 LGDKLDE 1037
Cdd:PRK15127 1033 FSRKNED 1039
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
1-1029 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 1092.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 1 MPKFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSS 80
Cdd:PRK10555 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 81 SSASNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVVAKANAGFLMVVALQSDTPTINRDALNDIVGS 160
Cdd:PRK10555 81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 161 RVLDQVSRIPGVGSTQQFGSEYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALGSDPSPEGQHFTATVSAEGRF 240
Cdd:PRK10555 161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 241 SSPQEFENIILRANADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPAG 320
Cdd:PRK10555 241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 321 VTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVL 400
Cdd:PRK10555 321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 401 AIGIVVDDAIVVIENVERIMTEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMAF 480
Cdd:PRK10555 401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 481 SAFLALGFTPALCATFLKP---THNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHAPRWMILFVVLTALCGFLFTRMPG 557
Cdd:PRK10555 481 SVLVAMILTPALCATLLKPlkkGEHHGQKGFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPT 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 558 SFLPEEDQGYALAIVQLPPGSTKGQTNEVFAQMRG--ILEKQDGYEGMLQVAGFSFVGSGENVGMGFIRLKPWEERKF-- 633
Cdd:PRK10555 561 SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKyyFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSkt 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 634 -TAPEFIQNMNGAFYGIKEAQIFVVNLPTVQGLGQFGGFDMWLQDRSGAGYEQLTQARNILLGQAAQKPDhLVGVRPNGL 712
Cdd:PRK10555 641 gTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNPE-LTRVRHNGL 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 713 ENAPQLQLHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYspsslTQNADG 792
Cdd:PRK10555 720 DDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWY-----VRNKDG 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 793 TnaMIPLNTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIVNdDLPAGFGYDWSGMSYQEILAGNAA 872
Cdd:PRK10555 795 G--MVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVK-QLPNGFGLEWTAMSYQERLSGAQA 871
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 873 TLLLVLSIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVEQR 952
Cdd:PRK10555 872 PALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMN 951
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 924469094 953 AAGKNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVRR 1029
Cdd:PRK10555 952 QKGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVLVRR 1028
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1028 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1074.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 1 MPKFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSS 80
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 81 SSaSNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVVAKANAGFLMVVALQSDTPTINRDALNDIVGS 160
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 161 RVLDQVSRIPGVGSTQQFG-SEYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALgsdpspEGQHFTATVSAEGR 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGgSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 240 FSSPQEFENIILRaNADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPA 319
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 320 GVTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMV 399
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 400 LAIGIVVDDAIVVIENVERIMTEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMA 479
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 480 FSAFLALGFTPALCATFLKPTHNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHAPRWMILFVVLTALCGFLFTRMPGSF 559
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKHGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEF 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 560 LPEEDQGYALAIVQLPPGSTKGQTNEVFAQMRGILEKQDGYEGMLQVAGFSFVG--SGENVGMGFIRLKPWEERKF---T 634
Cdd:pfam00873 553 LPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKERPGpekS 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 635 APEFIQNMNGAFYGIKEAQIFVVNLPTVQGLGQFGGFDMWLQD-RSGAGYEQLTQARNILLGQAAQKPDhLVGVRPNGLE 713
Cdd:pfam00873 633 VQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG-LSDVRSDGQE 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 714 NAPQLQLHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYSPssltqNADGT 793
Cdd:pfam00873 712 DQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVR-----NPYGK 786
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 794 naMIPLNTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIV-NDDLPAGFGYDWSGMSYQEILAGNAA 872
Cdd:pfam00873 787 --MIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAkQVKLPPGYGYTWTGQFEQEQLAGNSL 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 873 TLLLVLSIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVEQR 952
Cdd:pfam00873 865 PILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELR 944
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 924469094 953 AA-GKNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVR 1028
Cdd:pfam00873 945 EQeGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
1-1032 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 1022.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 1 MPKFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSS 80
Cdd:PRK09577 1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 81 SSaSNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVVAKANAGFLMVVALQSDTPTINRDALNDIVGS 160
Cdd:PRK09577 81 TS-SAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 161 RVLDQVSRIPGVGSTQQFGSEYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALGSDPSPEGQHFTATVSAEGRF 240
Cdd:PRK09577 160 NVLQALRRVEGVGKVQFWGAEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 241 SSPQEFENIILRANADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPAG 320
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 321 VTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVL 400
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 401 AIGIVVDDAIVVIENVERIMTEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMAF 480
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 481 SAFLALGFTPALCATFLKPTHNDNPNI--VYRTFNKYYDKISHTYVGHITSAVRHAPRWMILFVVLTALCGFLFTRMPGS 558
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPVDGDHHEKrgFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLPTA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 559 FLPEEDQGYALAIVQLPPGSTKGQTNEVFAQMRGILEKQDGYEGMLQVAGFSFVGSGENVGMGFIRLKPWEERKFTAPE- 637
Cdd:PRK09577 560 FLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGEGPNGGMIFVTLKDWKERKAARDHv 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 638 --FIQNMNGAFYGIKEAQIFVVNLPTVQGLGQFGGFDMWLQDRSGAGYEQLTQARNILLGQAAQKPdHLVGVRPNGLENA 715
Cdd:PRK09577 640 qaIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDP-ALTDLMFAGTQDA 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 716 PQLQLHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYspsslTQNADGTna 795
Cdd:PRK09577 719 PQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLR-----VRNAQGE-- 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 796 MIPLNTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIVNdDLPAGFGYDWSGMSYQEILAGNAATLL 875
Cdd:PRK09577 792 MVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAA-TLPAGIGYAWSGQSFEERLSGAQAPML 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 876 LVLSIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVEQRAAG 955
Cdd:PRK09577 871 FALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVAQR 950
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 924469094 956 KNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVRRMLG 1032
Cdd:PRK09577 951 MSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVGRLFD 1027
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-1029 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 728.35 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 5 FIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSSSSaS 84
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS-S 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 85 NGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQgVVVAKANAG--FLMVVALQSDTptINRDALNDIVGSRV 162
Cdd:NF033617 83 LGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDP-PVYRKANSAdtPIMYIGLTSEE--MPRGQLTDYAERVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 163 LDQVSRIPGVGSTQQFGSEY-AMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALgsdpspEGQHFTATVSAEGRFS 241
Cdd:NF033617 160 APKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAV------RGDSVVSTVRANDQLK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 242 SPQEFENIILRANADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPAGV 321
Cdd:NF033617 234 TAEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNI 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 322 TWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVLA 401
Cdd:NF033617 314 KVNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 402 IGIVVDDAIVVIENVERIMtEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMAFS 481
Cdd:NF033617 394 IGLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIIS 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 482 AFLALGFTPALCATFLKptHNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHaPRWMILFVVLT-ALCGFLFTRMPGSFL 560
Cdd:NF033617 473 GIVALTLTPMMCSRLLK--ANEKPGRFARAVDRFFDGLTARYGRGLKWVLKH-RPLTLVVALATlALLPLLYVFIPKELA 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 561 PEEDQGYALAIVQLPPGSTKGQTNEVFAQMRGILEKQDGYEgmlQVAGFSFVGS--GENVGMGFIRLKPWEERKFTAPEF 638
Cdd:NF033617 550 PSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQ---SLTSFNGVGGnpGDNTGFGIINLKPWDERDVSAQEI 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 639 IQNMNGAFYGIKEAQIFVVNLPTVQGLGQfGGFDMWLQDRSGAGYEQLTQARNILLGQAAQKPdHLVGVRPNGLENAPQL 718
Cdd:NF033617 627 IDRLRPKLAKVPGMDLFLFPLQDLPGGAG-SSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSP-QFADVDSDLQDKGPEL 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 719 QLHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYSPSSltqnaDGTnaMIP 798
Cdd:NF033617 705 NVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSN-----DGK--LVP 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 799 LNTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIVNDDLPAGFGYDWSGMSYQEILAGNAATLLLVL 878
Cdd:NF033617 778 LSTLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKELLPSGISGSFQGAARAFQEEGSSLLFLFLL 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 879 SIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKNAILIVEFAVE-QRAAGKN 957
Cdd:NF033617 858 ALAAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANElQRHQGLS 937
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 924469094 958 LRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVRR 1029
Cdd:NF033617 938 RREAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
5-1029 |
3.31e-167 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 518.62 E-value: 3.31e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 5 FIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSSSSAS 84
Cdd:PRK09579 7 FIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 85 NgRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVVAKANAGFLMVVALQSDTptINRDALNDIVGSRVLD 164
Cdd:PRK09579 87 N-FSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISFYSEE--MSNPQITDYLSRVIQP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 165 QVSRIPGVGSTQQFGSE-YAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALgsdpspEGQHFTATVSAEGRFSSP 243
Cdd:PRK09579 164 KLATLPGMAEAEILGNQvFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEV------KGEYVVTSINASTELKSA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 244 QEFENIILRANADgSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPAGVTW 323
Cdd:PRK09579 238 EAFAAIPVKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 324 FSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVLAIG 403
Cdd:PRK09579 317 SIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 404 IVVDDAIVVIENVERIMtEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMAFSAF 483
Cdd:PRK09579 397 LVVDDAIVVVENIHRHI-EEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGI 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 484 LALGFTPALCATFLKptHNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHAPRWMILFVVLTALCGFLFTRMPGSFLPEE 563
Cdd:PRK09579 476 VALTLSPMMCALLLR--HEENPSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSELAPEE 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 564 DQGYALAIVQLPPGSTKGQTNEVFAQMRGILEKQDGYEGMLQVAGFSFVGSGenVGmGFIrLKPWEERKFTAPEFIQNMN 643
Cdd:PRK09579 554 DQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQSG--IG-GFL-LKPWNERERTQMELLPLVQ 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 644 GAFYGIKEAQIFVVNLPTVQGLGQFGGFDMWLQdrSGAGYEQLTQARNiLLGQAAQKPDHLVGVRPNGLENAPQLQLHVD 723
Cdd:PRK09579 630 AKLEEIPGLQIFGFNLPSLPGTGEGLPFQFVIN--TANDYESLLQVAQ-RVKQRAQESGKFAFLDIDLAFDKPEVVVDID 706
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 724 RVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQADGPYRTGQESLKSFYspsslTQNADGtnAMIPLNTVV 803
Cdd:PRK09579 707 RAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYY-----VKNEQG--QLLPLSTLI 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 804 KSEWVSAPPSLSRYNGYSAINIVGsqAPGTSSGEAMQTMEGIVNDDLPAGFGYDWSGMSYQEILAGNAATLLLVLSIVVV 883
Cdd:PRK09579 780 TLSDRARPRQLNQFQQLNSAIISG--FPIVSMGEAIETVQQIAREEAPEGFAFDYAGASRQYVQEGSALWVTFGLALAII 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 884 FLCLAALYESWSIPVAVLLVVPLGVLGALgLSMLRGLPN-DLFFKIGLITVIGLAAKNAILIVEFAVEQR-AAGKNLRDA 961
Cdd:PRK09579 858 FLVLAAQFESFRDPLVILVTVPLSICGAL-IPLFLGVSSmNIYTQVGLVTLIGLISKHGILIVEFANQLRhEQGLSRREA 936
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 924469094 962 TIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVRR 1029
Cdd:PRK09579 937 IEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLAK 1004
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
3-1029 |
1.67e-139 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 446.01 E-value: 1.67e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 3 KFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSSSS 82
Cdd:COG3696 7 RFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 83 AsNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQ------GVvvakanaGFLMVVALQSDTPTINRDALND 156
Cdd:COG3696 87 R-FGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPElgpistGL-------GEIYQYTLESDPGKYSLMELRT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 157 IVGSRVLDQVSRIPGV-------GSTQQFgseyamNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALgsdPSPEGQH 229
Cdd:COG3696 159 LQDWVIRPQLRSVPGVaevnsfgGFVKQY------QVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYI---ERGGQEY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 230 FtatVSAEGRFSSPQEFENIILrANADGSRVLLKDIARVAFG-ANNYGfDTQYNGKPTGAFAI-QLLPGANALNVAEAVR 307
Cdd:COG3696 230 L---VRGIGLIRSLEDIENIVV-KTRNGTPVLLRDVAEVRIGpAPRRG-AATLNGEGEVVGGIvLMLKGENALEVIEAVK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 308 AKMDELQPSFPAGVTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIG 387
Cdd:COG3696 305 AKLAELKPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFG 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 388 FTINQLTLFAMVLAIGIVVDDAIVVIENVERIMTEEGLAPKPAT-----QKAMTQITGAVVAITVVLAAVFIPS-ALQgG 461
Cdd:COG3696 385 ISANLMSLGGLAIDFGIIVDGAVVMVENILRRLEENRAAGTPRErlevvLEAAREVRRPIFFATLIIILVFLPIfTLE-G 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 462 AAGEIYKQFALTIAISMAFSAFLALGFTPALCATFLKPTHNDNPNIVYRTFNKYYDKIshtyvghITSAVRHAPRWMILF 541
Cdd:COG3696 464 VEGKLFRPMALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKENPLVRWLKRLYRPL-------LRWALRHPKLVLAVA 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 542 VVLTALCGFLFTRMPGSFLPEEDQGyALAI-VQLPPGSTKGQTNEVFAQMRGILEKQDGYEgmlQVagFSFVGSGE---- 616
Cdd:COG3696 537 LVLLVLALALFPRLGSEFLPELDEG-DLLVmATLPPGISLEESVELGQQVERILKSFPEVE---SV--VSRTGRAEdatd 610
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 617 ----NVGMGFIRLKPWEE--RKFTAPEFIQNMNGAFYGIkeaqifvvnlPTVQ-GLGQFggfdmwLQDRSGagyEQLTQA 689
Cdd:COG3696 611 pmgvNMSETFVILKPRSEwrSGRTKEELIAEMREALEQI----------PGVNfNFSQP------IQMRVD---ELLSGV 671
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 690 R------------NILLGQAAQKPDHLVGVRpnGLENA--------PQLQLHVDRVQAQSMGMSVSDVYSTIQLMLAPVY 749
Cdd:COG3696 672 RadvavkifgddlDVLRRLAEQIEAVLKTVP--GAADVqvervtglPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKA 749
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 750 VNDfFYEGRiKR--VTMQADGPYRTGQESLKSFYSPSSltqnadgTNAMIPLNTVVKSEWVSAPPSLSRYNG--YSAI-- 823
Cdd:COG3696 750 VGQ-VYEGE-RRfdIVVRLPEELRDDPEAIRNLPIPTP-------SGAQVPLSQVADIEVVEGPNQISRENGrrRIVVqa 820
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 824 NIVGSqAPGTSSGEAMQTMEGIVndDLPAGFGYDWSGMS-YQE----------------ILA------GNAAtlllvlsi 880
Cdd:COG3696 821 NVRGR-DLGSFVAEAQAKVAEQV--KLPPGYYIEWGGQFeNLQratarlaivvplalllIFLllylafGSVR-------- 889
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 881 vvvflcLAALyeswsipvavllvvplgVLGALGLSM--------LRGLPndlfFKI----GLITVIGLAAKNAILIVEFA 948
Cdd:COG3696 890 ------DALL-----------------ILLNVPFALiggvlalwLRGMP----LSVsagvGFIALFGVAVLNGVVLVSYI 942
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 949 VEQRAAGKNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLMIPVFFVVVR 1028
Cdd:COG3696 943 NQLRAEGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFG 1022
|
.
gi 924469094 1029 R 1029
Cdd:COG3696 1023 R 1023
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
5-1030 |
7.15e-114 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 377.14 E-value: 7.15e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 5 FIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQL---TGIDHLlyfsSS 81
Cdd:PRK10614 7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLgriAGVNEM----TS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 82 SASNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVvAKANA--GFLMVVALQSDTptINRDALNDIVG 159
Cdd:PRK10614 83 SSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTY-RKANPsdAPIMILTLTSDT--YSQGQLYDFAS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 160 SRVLDQVSRIPGVGSTQQFGSEY-AMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALGSDPspegQHFTATVSAEg 238
Cdd:PRK10614 160 TQLAQTISQIDGVGDVDVGGSSLpAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGT----HRWQIQTNDE- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 239 rFSSPQEFENIILRANaDGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFP 318
Cdd:PRK10614 235 -LKTAAEYQPLIIHYN-NGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 319 AGVTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAM 398
Cdd:PRK10614 313 AAIDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMAL 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 399 VLAIGIVVDDAIVVIENVERIMtEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISM 478
Cdd:PRK10614 393 TIATGFVVDDAIVVLENISRHL-EAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAI 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 479 AFSAFLALGFTPALCATFLKPTHNDNPNIVyRTFNKYYDKISHTYVGHITSAVRHApRW-MILFVVLTALCGFLFTRMPG 557
Cdd:PRK10614 472 GISLLVSLTLTPMMCAWLLKSSKPREQKRL-RGFGRMLVALQQGYGRSLKWVLNHT-RWvGVVLLGTIALNVWLYISIPK 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 558 SFLPEEDQGYALAIVQlppgstkGQTNEVFAQMRGILE------KQDgyEGMLQVAGFSfVGSGENVGMGFIRLKPWEER 631
Cdd:PRK10614 550 TFFPEQDTGRLMGFIQ-------ADQSISFQAMRGKLQdfmkiiRDD--PAVDNVTGFT-GGSRVNSGMMFITLKPLSER 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 632 KFTAPEFIQNMNGAFYGIKEAQIFvvnLPTVQGLgQFGGfdmwLQDRSGAGYEQLTQARNIL------LGQAAQKPDHLV 705
Cdd:PRK10614 620 SETAQQVIDRLRVKLAKEPGANLF---LMAVQDI-RVGG----RQSNASYQYTLLSDDLAALrewepkIRKALAALPELA 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 706 GVRPNGLENAPQLQLHVDRVQAQSMGMSVSDVYSTIqlmlapvyvNDFFYEGRIK---------RVTMQADGPYRTGQES 776
Cdd:PRK10614 692 DVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLL---------NNAFGQRQIStiyqplnqyKVVMEVDPRYTQDISA 762
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 777 LKSFYspsslTQNADGTNamIPLNTVVKSEWVSAPPSLSrYNGYSAINIVGSQAP-GTSSGEAMQTMEGIVND-DLPAGF 854
Cdd:PRK10614 763 LEKMF-----VINNEGKA--IPLSYFAKWQPANAPLSVN-HQGLSAASTISFNLPtGKSLSDASAAIERAMTQlGVPSTV 834
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 855 GYDWSGMS--YQEILagNAATLLLVLSIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLIT 932
Cdd:PRK10614 835 RGSFAGTAqvFQETM--NSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIML 912
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 933 VIGLAAKNAILIVEFAVE-QRAAGKNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLF 1011
Cdd:PRK10614 913 LIGIVKKNAIMMVDFALEaQRNGNLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVM 992
|
1050
....*....|....*....
gi 924469094 1012 ATLLGLLMIPVFFVVVRRM 1030
Cdd:PRK10614 993 SQLLTLYTTPVVYLFFDRL 1011
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
3-1030 |
3.75e-108 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 361.74 E-value: 3.75e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 3 KFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSSSS 82
Cdd:PRK10503 14 RLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 83 aSNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEVTQQGVVvAKANAGFLMVVALQSDTPTINRDALNDIVGSRV 162
Cdd:PRK10503 94 -SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVY-SKVNPADPPIMTLAVTSTAMPMTQVEDMVETRV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 163 LDQVSRIPGVG-STQQFGSEYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALgsdpspEGQHFTATVSAEGRFS 241
Cdd:PRK10503 172 AQKISQVSGVGlVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSL------DGPTRAVTLSANDQMQ 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 242 SPQEFENIILrANADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQPSFPAGV 321
Cdd:PRK10503 246 SAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSV 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 322 TWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVLA 401
Cdd:PRK10503 325 KVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIA 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 402 IGIVVDDAIVVIENVERIMtEEGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMAFS 481
Cdd:PRK10503 405 TGFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILIS 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 482 AFLALGFTPALCATFLKPTHNDNPNIVYRTFNKYYDKISHTYVGHITSAVRHAprWMILFVVLT--ALCGFLFTRMPGSF 559
Cdd:PRK10503 484 AVVSLTLTPMMCARMLSQESLRKQNRFSRASERMFDRVIAAYGRGLAKVLNHP--WLTLSVALStlLLTVLLWIFIPKGF 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 560 LPEEDQGYALAIVQLPPGSTKGQTNEVFAQMRGILEKQDGYEGMLQVAGFSFVGSGENVGMGFIRLKPWEERKFTAPEFI 639
Cdd:PRK10503 562 FPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVI 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 640 QNMNGAFYGIKEAQIFvvnLPTVQglgqfggfDMWLQDRSGAGYEQLTQARNIL---------LGQAAQKPDHLVGVRPN 710
Cdd:PRK10503 642 ARLQTAVAKVPGVDLY---LQPTQ--------DLTIDTQVSRTQYQFTLQATSLdalstwvpkLMEKLQQLPQLSDVSSD 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 711 GLENAPQLQLHVDRVQAQSMGMSVSDVYSTI-----QLMLAPVYVNDFFYegrikRVTMQADGPYRTGQESLKSFYSPSS 785
Cdd:PRK10503 711 WQDKGLVAYVNVDRDSASRLGISMADVDNALynafgQRLISTIYTQANQY-----RVVLEHNTENTPGLAALDTIRLTSS 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 786 ltqnaDGtnAMIPLNTVVKSEWVSAPPSLSRYNGYSAINIVGSQAPGTSSGEAMQTMEGIVND-DLPAGFGYDWSGMSyq 864
Cdd:PRK10503 786 -----DG--GVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTlNLPADITTQFQGST-- 856
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 865 eiLAGNAATLLL----VLSIVVVFLCLAALYESWSIPVAVLLVVPLGVLGALGLSMLRGLPNDLFFKIGLITVIGLAAKN 940
Cdd:PRK10503 857 --LAFQSALGSTvwliVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKN 934
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 941 AILIVEFAV-EQRAAGKNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHAIGTGVIGGMLFATLLGLLM 1019
Cdd:PRK10503 935 AIMMIDFALaAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFT 1014
|
1050
....*....|.
gi 924469094 1020 IPVFFVVVRRM 1030
Cdd:PRK10503 1015 TPVIYLLFDRL 1025
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
3-1038 |
6.29e-88 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 305.92 E-value: 6.29e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 3 KFFIEHPVFAWVVAILISLSGVIAILNLGVESYPNIAPPQVTVSATYPGASADTTEKSVTQVIEQQLTGIDHLLYFSSSS 82
Cdd:TIGR00914 7 SFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 83 aSNGRAQITLTFETGTDPDIAQVQVQNKVSLATPRLPSEV-TQQGVVVAKANAGFLMVVALQSDTPTINRDA-----LND 156
Cdd:TIGR00914 87 -RYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVsPEMGPISTGLGEIFLYTVEAEEGARKKDGGAytltdLRT 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 157 IVGSRVLDQVSRIPGVGSTQQFGS-EYAMNIWLNPEKMQGYGLSASQVLAAVRAQNVQFAAGALgsdpspEGQHFTATVS 235
Cdd:TIGR00914 166 IQDWIIRPQLRTVPGVAEVNSIGGyVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYI------ERRGEQYLVR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 236 AEGRFSSPQEFENIILrANADGSRVLLKDIARVAFGANNYGFDTQYNGKPTGAFAIQLLPGANALNVAEAVRAKMDELQP 315
Cdd:TIGR00914 240 APGQVQSMDDIRNIVI-ATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 316 SFPAGVTWFSPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTL 395
Cdd:TIGR00914 319 TLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 396 FAmvLAIGIVVDDAIVVIENVERIMTE----EGLAPKPATQ-KAMTQITGAVVAITV----VLAAVFIPSALQGGAAGEI 466
Cdd:TIGR00914 399 GA--LDFGLIVDGAVVIVENAHRRLAEaqhhHGRQLTLKERlHEVFAASREVRRPLIfgqlIITLVFLPIFTLTGVEGKM 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 467 YKQFALTIAISMAFSAFLALGFTPALCATFLKPTHNDNPNIVYRTFNKYYDKishtyvghITSAVRHAPRWMILFVVLT- 545
Cdd:TIGR00914 477 FHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKENRLMRVLKRRYEP--------LLERVLAWPAVVLGAAAVSi 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 546 ALCGFLFTRMPGSFLPEEDQGYALAIVQLPPGSTKGQTnevfAQMRGILEKQdgYEGMLQVAG-FSFVGSGE-------- 616
Cdd:TIGR00914 549 VLVVWIASRVGGEFIPSLNEGDLAYQALRIPGTSLAQS----VAMQQTLEKL--IKSFPEVARvFAKTGTAEiatdpmpp 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 617 NVGMGFIRLKP---WEERKFTAPEFIQNMNGafygiKEAQIFVVNLPTVQGLGQfgGFDMWLQD-RSGAGYEQLTQARNI 692
Cdd:TIGR00914 623 NASDTYIILKPesqWPEGKKTKEDLIEEIQE-----ATVRIPGNNYEFTQPIQM--RFNELISGvRSDVAVKVFGDDLDD 695
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 693 LLGQA------AQKPDHLVGVRPNGLENAPQLQLHVDRVQAQSMGMSVSDVYSTIQLMLAPVYVNDFFYEGRIKRVTMQA 766
Cdd:TIGR00914 696 LDATAekisavLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRL 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 767 DGPYRTGQESLKSFysPSSLTQNADGTNAMIPLNTVVKSEWVSAPPSLSRYNGYSAINI---VGSQAPGTSSGEAMQTME 843
Cdd:TIGR00914 776 PESLRESPQALRQL--PIPLPLSEDARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVsanVRGRDLGSFVDDAKKAIA 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 844 GIVNddLPAGFGYDWSGmsyQEILAGNAATLLLVLSIVVVFLCLAALYESW-SIPVAVLLVVPLGVLGALGLSML--RGL 920
Cdd:TIGR00914 854 EQVK--LPPGYWITWGG---QFEQLQSATKRLQIVVPVTLLLIFVLLYAAFgNVKDALLVFTGIPFALTGGVFALwlRGI 928
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 921 PNDLFFKIGLITVIGLAAKNAILIVEFAVEQRAAGKNLRDATIEAARLRFRPILMTSFAFIMGVIPMAISTGAGANSRHA 1000
Cdd:TIGR00914 929 PLSISAAVGFIALSGVAVLNGLVMISFIRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRP 1008
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|
gi 924469094 1001 IGTGVIGGMLFATLLGLLMIPVFFVVV--RRMLGDKLDEP 1038
Cdd:TIGR00914 1009 LATVVIGGIITATLLTLFVLPALYRLVhrRRHKGRKEHEP 1048
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
302-565 |
2.11e-18 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 90.69 E-value: 2.11e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 302 VAEAVRAKMDELQPsfpAGVTWF---SPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLG 378
Cdd:COG1033 182 VVAEIRAIIAKYED---PGVEVYltgFPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIW 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 379 TFLGMWMIGFTINQLTLFAMVLAIGIVVDDAIVVIenvERIMTE--EGLAPKPATQKAMTQITGAVV--AITVVLA-AVF 453
Cdd:COG1033 259 TLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLL---NRYREErrKGLDKREALREALRKLGPPVLltSLTTAIGfLSL 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 454 IPSALQggaageIYKQFALTIAISMAFSAFLALGFTPALCATFLKPTHNDNPNIVYRTFNKYYDKISHTyvghitsAVRH 533
Cdd:COG1033 336 LFSDIP------PIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPPELGRLLAKLARF-------VLRR 402
|
250 260 270
....*....|....*....|....*....|....*..
gi 924469094 534 APRWMILFVVLTALCGFLFTRM-----PGSFLPEEDQ 565
Cdd:COG1033 403 PKVILVVALVLAVVSLYGISRLkveydFEDYLPEDSP 439
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
294-496 |
1.27e-17 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 88.38 E-value: 1.27e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 294 LPGANALNVAEAVRAKMDELQPSFPAGVTWFSPydSTTFVKIS---IQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTL 370
Cdd:COG1033 560 LDSEEIKALVEEVRAFLAENFPPDGVEVTLTGS--AVLFAAINesvIESQIRSLLLALLLIFLLLLLAFRSLRLGLISLI 637
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 371 VIPVALLGTFLGMWMIGFTINQLTLFAMVLAIGIVVDDAIVVIENVERIMtEEGLAPKPATQKAMTQITGAVVAITVVLA 450
Cdd:COG1033 638 PNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREER-RKGGDLEEAIRRALRTTGKAILFTSLTLA 716
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 924469094 451 AVFIPSALqggAAGEIYKQFALTIAISMAFSAFLALGFTPALCATF 496
Cdd:COG1033 717 AGFGVLLF---SSFPPLADFGLLLALGLLVALLAALLLLPALLLLL 759
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
152-501 |
1.20e-13 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 75.84 E-value: 1.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 152 DALNDIvGSRVLDQVSRIPGVGST---QQFGSEYaMNIWLNPEKMQGYGLSASQVLAAVRAqnvqfaagALGsdpspeGQ 228
Cdd:COG3696 685 DVLRRL-AEQIEAVLKTVPGAADVqveRVTGLPQ-LDIRIDRDAAARYGLNVADVQDVVET--------AIG------GK 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 229 HFTATVSAEGRF-----------SSPQEFENIILRAnADGSRVLLKDIARVAF--GANN-----------YGFDTQynGK 284
Cdd:COG3696 749 AVGQVYEGERRFdivvrlpeelrDDPEAIRNLPIPT-PSGAQVPLSQVADIEVveGPNQisrengrrrivVQANVR--GR 825
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 285 PTGAFaiqllpganalnVAEAvRAKMDElQPSFPAG--VTWfspydSTTFVkiSIQEVVKTLFEAVFLVFLVMLIFL--- 359
Cdd:COG3696 826 DLGSF------------VAEA-QAKVAE-QVKLPPGyyIEW-----GGQFE--NLQRATARLAIVVPLALLLIFLLLyla 884
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 360 -QNFRATLIPTLVIPVALLGTFLGMW----------MIGFtinqLTLFamvlaiGIVVDDAIVVIENVERIMtEEGLAPK 428
Cdd:COG3696 885 fGSVRDALLILLNVPFALIGGVLALWlrgmplsvsaGVGF----IALF------GVAVLNGVVLVSYINQLR-AEGLDLR 953
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 924469094 429 PATqkamtqITGAV-----VAITVVLAAV-FIPSALQGGAAGEIYKQFALTIAISMAFSAFLALGFTPALCATFLKPTH 501
Cdd:COG3696 954 EAI------IEGALerlrpVLMTALVAALgLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRL 1026
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
347-496 |
8.87e-08 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 55.38 E-value: 8.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 347 AVFLVFLVMLIFLQNFRATLIPTLVIPVALlGTFLGMWMI-----GFTINQLTL-FAMVLAIGIVVDDAIVVIEnveRIM 420
Cdd:pfam03176 151 TLVVIFIILLIVYRSVVAALLPLLTVGLSL-GAAQGLVAIlahilGIGLSTFALnLLVVLLIAVGTDYALFLVS---RYR 226
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 924469094 421 TE--EGLAPKPATQKAMTQITGAVVAITVVLAAVFIPSALqggAAGEIYKQFALTIAISMAFSAFLALGFTPALCATF 496
Cdd:pfam03176 227 EElrAGEDREEAVIRAVRGTGKVVTAAGLTVAIAMLALSF---ARLPVFAQVGPTIAIGVLVDVLAALTLLPALLALL 301
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
294-496 |
9.20e-08 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 56.31 E-value: 9.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 294 LPGANALNVAEAVRAKMDELQPSFPAGVTWF---SPYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTL 370
Cdd:COG2409 122 LDGDAGDEAAEAVDALRDAVAAAPAPGLTVYvtgPAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLL 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 371 VIPVALLGTFLGMWMIG--FTINQLTL-FAMVLAIGIVVDDAIVVI----ENVERimteeGLAPKPATQKAMTQITGAVV 443
Cdd:COG2409 202 TAGLAVGVALGLLALLAafTDVSSFAPnLLTMLGLGVGIDYALFLVsryrEELRA-----GEDREEAVARAVATAGRAVL 276
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 924469094 444 --AITVVLAA---VFIPSAlqggaageIYKQFALTIAISMAFSAFLALGFTPALCATF 496
Cdd:COG2409 277 fsGLTVAIALlglLLAGLP--------FLRSMGPAAAIGVAVAVLAALTLLPALLALL 326
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
336-492 |
4.91e-07 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 53.58 E-value: 4.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 336 SIQEVVKTLFEAVFLVFLVMLIFLQNFRatliptLVIPVALLG----TFLGMWMIGFTinqLTL---FAMVLAIGIVVdD 408
Cdd:COG0342 269 SIEKGLIAGLIGLLLVALFMLLYYRLPG------LVANIALALnvvlLLGVLSLLGAT---LTLpgiAGIILTIGMAV-D 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 409 AIVVIenVERIMtEEGLAPKPATQ-------KAMTQITGAvvAITVVLAAV----FIPSALQGgaageiykqFALTIAIS 477
Cdd:COG0342 339 ANVLI--FERIR-EELRAGRSLRAaieagfkRAFSTILDA--NVTTLIAAVvlfvLGTGPVKG---------FAVTLILG 404
|
170
....*....|....*
gi 924469094 478 MAFSAFLALGFTPAL 492
Cdd:COG0342 405 ILISMFTAVPVTRPL 419
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
347-500 |
1.06e-05 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 49.83 E-value: 1.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 347 AVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVLAIGIVVDDAIVVIENVERIMTEEGLA 426
Cdd:PRK09579 853 ALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLS 932
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 924469094 427 PKPATQKAMTQITGAVVAITVVLAAVFIPSALQGGAAGEIYKQFALTIAISMAFSAFLALGFTPALCATFLKPT 500
Cdd:PRK09579 933 RREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLAKPD 1006
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
223-492 |
1.26e-04 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 45.74 E-value: 1.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 223 PSPEGQHFT-ATVSAEGRFSSPQefenIILRANADGSRVLLKdiarvaFGANNYG------FDTQY-------------N 282
Cdd:TIGR01129 133 PVLTGDHITdATSSVDQRSGQPV----VSFSLDSEGARIFGD------FTQANIGkrlaivLDNKVvsaptiqeaitggS 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 283 GKPTGAFAIQllpgaNALNVAEAVRAKmdelqpSFPAGVT-----WFSPydstTFVKISIQEVVKTLFEAVFLVFLVMLI 357
Cdd:TIGR01129 203 GQITGNFTAE-----EANDLALVLRSG------ALPAPLQileerTIGP----SLGADSIEAGIKAGLIGLVLVLVFMIL 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 358 FLQNFraTLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVLAIGIVVdDAIVVIenVERIMTE--EGLAPKPAT---- 431
Cdd:TIGR01129 268 YYRLF--GLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAV-DANVLI--YERIKEElrLGKSVRQAIeagf 342
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 924469094 432 QKAMTQITGAvvAITVVLAAVFIpSALQGGAAgeiyKQFALTIAISMAFSAFLALGFTPAL 492
Cdd:TIGR01129 343 ERAFSTIFDA--NITTLIAALIL-YVFGTGPV----KGFAVTLAIGIIASLFTALVFTRLL 396
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
298-491 |
3.09e-04 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 44.84 E-value: 3.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 298 NALNVAEAVRAKMDELQpsfpaGVTWFS-PYDSTTFVKISIQEVVKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVAL 376
Cdd:COG4258 603 RGVDDAAALRAAAAGLP-----GVRLVDrKAESSSLFGRYRNDALWLLLLALLLILLLLLLRLRSLRRALRVLLPPLLAV 677
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 377 LGTFLGMWMIGFTINQLTLFAMVLAIGIVVDDAIVVienverimtEEGLAPKPATQKAMTQITGAvVAITV----VLAAV 452
Cdd:COG4258 678 LLTLAILGLLGIPLNLFHLIALLLVLGIGIDYALFF---------TEGLLDKGELARTLLSILLA-ALTTLlgfgLLAFS 747
|
170 180 190
....*....|....*....|....*....|....*....
gi 924469094 453 FIPsALQGgaageiykqFALTIAISMAFSAFLALGFTPA 491
Cdd:COG4258 748 STP-ALRS---------FGLTVLLGILLALLLAPLLAPR 776
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
336-486 |
5.45e-04 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 42.24 E-value: 5.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 336 SIQEVVKTLFEAVFLVFLVMLIFLQNFRA-----TLIPTLVIPVALLGTFlgmwmiGFTINQLTLFAMVLAIGIVVDDAI 410
Cdd:TIGR00916 45 LIKAGIIALLIGLVLVLLYMLLRYEWRGAiaaiaALVHDVILILGVLSLF------GATLTLPGIAGLLTIIGYSVDDTV 118
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 924469094 411 VVIENV-ERIMTEEGLAPKPATQKAMTQITGAVV--AITVVLAAVFIpSALQGGAAgeiyKQFALTIAISMAFSAFLAL 486
Cdd:TIGR00916 119 VIFDRIrEELRKYKGRTFREAINLGINQTLSRIIdtNVTTLLAVLAL-YVFGGGAI----KGFALTLGIGVIAGTYSSI 192
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
350-497 |
8.24e-04 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 43.42 E-value: 8.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 350 LVFLVMLIFLQNFRATLIptLVIPVAL-LGTFLG-MWMIGFTINQLTLFAMVLAIGIVVDDAIVVIEN---VERIMTEEG 424
Cdd:TIGR00833 756 IVFMILALLLRAPVAPIV--LIGSVALsYLWALGlSVLAFQHILGAELHWSVLAGVFVLLVALGVDYNmllVSRIKEESP 833
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 924469094 425 LAPKPATQKAMTQITGAVVAITVVLAAVFIPSAlqgGAAGEIYKQFALTIAISMAFSAFLALGFTPALCATFL 497
Cdd:TIGR00833 834 AGNRTGIIRALGSTGGVITAAGLVFAGTMAALA---SAQLTAIAQFGFTVGVGILLDTFIVRSVTVPALTLLL 903
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
347-492 |
9.52e-04 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 42.90 E-value: 9.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 347 AVFLVFLVMLIF--LQNFRATLipTLVIPVALLgtFLGMWMIGFTinqLTL---FAMVLAIGIVVdDAIVVIenVERIMT 421
Cdd:PRK05812 306 GLALVLLFMILYyrLFGLIANI--ALVANLVLI--LAVLSLLGAT---LTLpgiAGIVLTIGMAV-DANVLI--FERIRE 375
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 924469094 422 E--EGLAPKPATQ----KAMTQITGAvvAITVVLAAVfipsALQGGAAGEIyKQFALTIAISMAFSAFLALGFTPAL 492
Cdd:PRK05812 376 ElrEGRSLRSAIEagfkRAFSTILDS--NITTLIAAI----ILYALGTGPV-KGFAVTLGIGILTSMFTAITVTRAL 445
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
324-496 |
9.54e-04 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 43.11 E-value: 9.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 324 FSPYDSTTFVKIS-----IQEVVKTLFE----AVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLT 394
Cdd:pfam02460 616 YPEFNVTVFDEDApfadqYLTILPSTIQniviTLICMFIVCFLFIPNPPCVFVITLAIASIDIGVFGFLSLWGVDLDPIS 695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 395 LFAMVLAIGIVVDDAIVVIENverIMTEEGLAPKPATQKAMTQI-----TGAVVAITVVLAAVFIPSalqggAAGEIykq 469
Cdd:pfam02460 696 MITIIMSIGFSVDFSAHIAYH---FVRSRGDTPAERVVDALEALgwpvfQGGLSTILGVLVLLFVPS-----YMVVV--- 764
|
170 180
....*....|....*....|....*..
gi 924469094 470 FALTIAISMAFSAFLALGFTPALCATF 496
Cdd:pfam02460 765 FFKTVFLVVAIGLLHGLFILPIILSLF 791
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
331-486 |
1.51e-03 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 42.84 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 331 TFVKISIQEV--VKTLfeavfLVFLVMLIFLQNFRATLIPTLVIPVALLGTFlgMWMIGFTINQLTLF------------ 396
Cdd:NF037998 426 TFKVNGISEFnpVVTL-----LMLIASIIFLLILAIAIMIYLLFAYRLLGLF--AIIIALTSISLTLYsptwfglaigpe 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 397 ---AMVLAIGIVVDDAIVVIENVERIMTEEGLAPKPATQKAMTQITGAVVAITVVLaavFIPS-ALQGGAAGEIyKQFAL 472
Cdd:NF037998 499 sitAIFIAIGLVLESCSLLFEAFKKHLYKNKRSIEESFKIANKETIGIIVDALVVL---LIPNlSLFWIGSNSI-KSFAT 574
|
170
....*....|....
gi 924469094 473 TIAISMAFSAFLAL 486
Cdd:NF037998 575 ILLVGVIISLVLVI 588
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
341-492 |
2.23e-03 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 42.13 E-value: 2.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 341 VKTLFEAVFLVFLVMLIFLQNFRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVLAIGIVVDDAIVVIENVErim 420
Cdd:TIGR00921 196 GTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYE--- 272
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 924469094 421 tEEGLAPKPATQKAMTQI--TGAVVAITVVLAAV-FIPSALQGGAAgeiYKQFALTIAISMAFSAFLALGFTPAL 492
Cdd:TIGR00921 273 -EERDIGRAKGEAIVTAVrrTGRAVLIALLTTSAgFAALALSEFPM---VSEFGLGLVAGLITAYLLTLLVLPAL 343
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
336-552 |
2.64e-03 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 41.76 E-value: 2.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 336 SIQEVVKTLFEAVFLVFLVMLIFLQnfRATLIPTLVIPVALLGTFLGMWMIGFTINQLTLFAMVLAIGIVVdDAIVVIen 415
Cdd:PRK13024 264 AIDAGIIAGIIGFALIFLFMLVYYG--LPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGIGMAV-DANVLI-- 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 924469094 416 VERIMTE--EGLAPKPATQKAMTQITGAVV--AITVVLAAVfipsALQGGAAGEIyKQFALTIAISMAFSAFLALGFTPA 491
Cdd:PRK13024 339 FERIKEElrKGKSLKKAFKKGFKNAFSTILdsNITTLIAAA----ILFFFGTGPV-KGFATTLIIGILASLFTAVFLTRL 413
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 924469094 492 LCATFLKptHNDNPNIVYRTFNKYYDKISHTYVGHIT-SAVRHAPRWMILFVVLTALCGFLF 552
Cdd:PRK13024 414 LLELLVK--RGDKKPFLFGVKKKKIHNINEGVTIFDRiDFVKKRKWFLIFSIVLVIAGIIIF 473
|
|
| |
