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Conserved domains on  [gi|936194510|ref|WP_054528661|]
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MULTISPECIES: protein lysine acetyltransferase [Citrobacter]

Protein Classification

bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase( domain architecture ID 11437151)

bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase containing an N-terminal domain similar to ADP-forming acetate--CoA ligase that catalyzes the formation of acetate and ATP from acetyl-CoA by using ADP and phosphate, and a C-terminal domain that may catalyze the transfer of an acetyl group from acetyl-CoA to a substrate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-700 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


:

Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 885.24  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510   1 MSQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVLAWPNINSLPFSPDLAVLCTNAS 80
Cdd:COG1042    1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  81 RNLALLEALGEKGCKTCIILSAP--------SAQHAELLACASRYNIRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAF 152
Cdd:COG1042   81 TVPDVVEECGEKGVKAAVVISAGfaetgeegAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 153 ISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEHLSDARRFVSAARSASRNKPILV 232
Cdd:COG1042  161 VSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVVV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 233 IKSGRSPAAQR--LLHTS--AGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMIISNGAAPAALALDEL 308
Cdd:COG1042  241 LKSGRSEAGARaaASHTGalAGSDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADAL 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 309 WSKNGKLATLSEDTCQKLRDALPEHVDIANPLDLRDDASSEHYVKTLDILLASQDFDALMVIHSPSAAAPGTESAQALIE 388
Cdd:COG1042  321 EDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALIE 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 389 AVKHHprGKFVslLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPAlPDNLTTNTAEAHN 468
Cdd:COG1042  401 AAKGS--GKPV--LASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA-SEDFDPDRERARA 475

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 469 LLQQAIAEGATSLDTHEVQPILQAYGLHTLPTWIASDSAEAVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTATEV 548
Cdd:COG1042  476 IIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAEAV 555

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 549 QQAANAIFDRVKMAWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMNLARY 628
Cdd:COG1042  556 RAAFEEILARVRAARPDARIDGVLVQPMVP--GGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALARE 633

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 936194510 629 LVIQGIKNKKIRARSALRPLDIAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASAEEFTALDVTLDIAPFAGD 700
Cdd:COG1042  634 MIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPP 705
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 722-874 1.52e-17

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 81.20  E-value: 1.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 722 NGERCLFRPILPEDEPHLQQFISQvtKEDLYYRYFSEIN-EFTHEDLANMTQIDYDREMAFVAVRCKDNhEEILGVTRAI 800
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLND--PEVARYLPGPPYSlEEARAWLERLLADWADGGALPFAIEDKED-GELIGVVGLY 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 936194510 801 S-DPDNVDAEFAVLVRSDLKGLGLGRRLMEKLIAYTRDH-GLIRLNGITMPNNRGMVALARKLGFVVDVQLEEGIV 874
Cdd:COG1670   81 DiDRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALV 156
 
Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-700 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 885.24  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510   1 MSQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVLAWPNINSLPFSPDLAVLCTNAS 80
Cdd:COG1042    1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  81 RNLALLEALGEKGCKTCIILSAP--------SAQHAELLACASRYNIRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAF 152
Cdd:COG1042   81 TVPDVVEECGEKGVKAAVVISAGfaetgeegAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 153 ISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEHLSDARRFVSAARSASRNKPILV 232
Cdd:COG1042  161 VSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVVV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 233 IKSGRSPAAQR--LLHTS--AGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMIISNGAAPAALALDEL 308
Cdd:COG1042  241 LKSGRSEAGARaaASHTGalAGSDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADAL 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 309 WSKNGKLATLSEDTCQKLRDALPEHVDIANPLDLRDDASSEHYVKTLDILLASQDFDALMVIHSPSAAAPGTESAQALIE 388
Cdd:COG1042  321 EDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALIE 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 389 AVKHHprGKFVslLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPAlPDNLTTNTAEAHN 468
Cdd:COG1042  401 AAKGS--GKPV--LASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA-SEDFDPDRERARA 475

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 469 LLQQAIAEGATSLDTHEVQPILQAYGLHTLPTWIASDSAEAVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTATEV 548
Cdd:COG1042  476 IIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAEAV 555

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 549 QQAANAIFDRVKMAWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMNLARY 628
Cdd:COG1042  556 RAAFEEILARVRAARPDARIDGVLVQPMVP--GGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALARE 633

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 936194510 629 LVIQGIKNKKIRARSALRPLDIAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASAEEFTALDVTLDIAPFAGD 700
Cdd:COG1042  634 MIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPP 705
AcCoA-syn-alpha TIGR02717
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it ...
 6-443 2.41e-137

acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.


Pssm-ID: 131764 [Multi-domain]  Cd Length: 447  Bit Score: 416.71  E-value: 2.41e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510    6 LEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVLAWPNINSLPFSPDLAVLCTNASRNLAL 85
Cdd:TIGR02717   1 LEHLFNPKSVAVIGASRDPGKVGYAIMKNLIEGGYKGKIYPVNPKAGEILGVKAYPSVLEIPDPVDLAVIVVPAKYVPQV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510   86 LEALGEKGCKTCIILSAPSAQ--------HAELLACASRYNIRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSA 157
Cdd:TIGR02717  81 VEECGEKGVKGAVVITAGFKEvgeegaelEQELVEIARKYGMRLLGPNCLGIINTHIKLNATFAPTMPKKGGIAFISQSG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  158 AVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEHLSDARRFVSAARSASRNKPILVIKSGR 237
Cdd:TIGR02717 161 ALLTALLDWAEKNGVGFSYFVSLGNKADIDESDLLEYLADDPDTKVILLYLEGIKDGRKFLKTAREISKKKPIVVLKSGT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  238 SPAAQRLL--HTS--AGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMIISNGAAPAALALDELWSKNG 313
Cdd:TIGR02717 241 SEAGAKAAssHTGalAGSDEAYDAAFKQAGVIRADSIEELFDLARLLSNQPLPKGNRVAIITNAGGPGVIATDACEENGL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  314 KLATLSEDTCQKLRDALPEHVDIANPLDLRDDASSEHYVKTLDILLASQDFDALMVIHSPSAAAPGTESAQALIEAVKHH 393
Cdd:TIGR02717 321 ELAELSEATKNKLRNILPPEASIKNPVDVLGDATPERYAKALKTVAEDENVDGVVVVLTPTAMTDPEEVAKGIIEGAKKS 400

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 936194510  394 PRgkfVSLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYR 443
Cdd:TIGR02717 401 NE---KPVVAGFMGGKSVDPAKRILEENGIPNYTFPERAVKALSALYRYA 447
ATP-grasp_5 pfam13549
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent ...
 472-690 3.84e-89

ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent carboxylate-amine ligase activity.


Pssm-ID: 463918 [Multi-domain]  Cd Length: 221  Bit Score: 282.06  E-value: 3.84e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  472 QAIAEGATSLDTHEVQPILQAYGLHTLPTWIASDSAEAVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTATEVQQA 551
Cdd:pfam13549   1 KALAEGRTVLTEPEAKALLAAYGIPVVPTRLARSPEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRSAEAVRAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  552 ANAIFDRVKMAWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMNLARYLvI 631
Cdd:pfam13549  81 YEEILERVRRYRPDARIEGVLVQPMAP--GGRELIVGVTRDPQFGPVIMFGLGGIAVEVLKDVAFRLPPLNMTLAREM-I 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  632 QGIKNKKIRARSALR-PLDIAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASAEEFTALDV 690
Cdd:pfam13549 158 RRTRAYKLLKGYRGEpPADLDALEDVLVRVSQLVIDFPEIRELDINPLLADEDGVVALDA 217
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 722-874 1.52e-17

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 81.20  E-value: 1.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 722 NGERCLFRPILPEDEPHLQQFISQvtKEDLYYRYFSEIN-EFTHEDLANMTQIDYDREMAFVAVRCKDNhEEILGVTRAI 800
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLND--PEVARYLPGPPYSlEEARAWLERLLADWADGGALPFAIEDKED-GELIGVVGLY 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 936194510 801 S-DPDNVDAEFAVLVRSDLKGLGLGRRLMEKLIAYTRDH-GLIRLNGITMPNNRGMVALARKLGFVVDVQLEEGIV 874
Cdd:COG1670   81 DiDRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALV 156
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 9-102 4.05e-14

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 68.69  E-value: 4.05e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510     9 LLRP-KSIAVIGASMKPNRAGYLMMRNLLAGG--FNGPVLP--VTPawkAVLGVLAWPNINSLP--FSPDLAVLCTNASR 81
Cdd:smart00881   1 LLNPnTSVAVVGASGNLGSFGLAVMRNLLEYGtkFVGGVYPgkVGP---KVDGVPVYDSVAEAPeeTGVDVAVIFVPAEA 77

                           90       100
                   ....*....|....*....|.
gi 936194510    82 NLALLEALGEKGCKTCIILSA 102
Cdd:smart00881  78 APDAIDEAIEAGIKGIVVITE 98
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 750-863 7.94e-11

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 60.22  E-value: 7.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  750 DLYYRYFSEinEFTHEDLANMTQIDYDREMAFVAVRckdNHEEILGVTRA--ISDPDNVDAEFAVLVRSDLKGLGLGRRL 827
Cdd:pfam00583   6 ELLSEEFPE--PWPDEPLDLLEDWDEDASEGFFVAE---EDGELVGFASLsiIDDEPPVGEIEGLAVAPEYRGKGIGTAL 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 936194510  828 MEKLIAYTRDHGLIRLNGITMPNNRGMVALARKLGF 863
Cdd:pfam00583  81 LQALLEWARERGCERIFLEVAADNLAAIALYEKLGF 116
 
Name Accession Description Interval E-value
PatZN COG1042
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
1-700 0e+00

Acyl-CoA synthetase (NDP forming) [Energy production and conversion];


Pssm-ID: 440664 [Multi-domain]  Cd Length: 708  Bit Score: 885.24  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510   1 MSQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVLAWPNINSLPFSPDLAVLCTNAS 80
Cdd:COG1042    1 MSTRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  81 RNLALLEALGEKGCKTCIILSAP--------SAQHAELLACASRYNIRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAF 152
Cdd:COG1042   81 TVPDVVEECGEKGVKAAVVISAGfaetgeegAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPVPPLPGNIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 153 ISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEHLSDARRFVSAARSASRNKPILV 232
Cdd:COG1042  161 VSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAARGKPVVV 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 233 IKSGRSPAAQR--LLHTS--AGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMIISNGAAPAALALDEL 308
Cdd:COG1042  241 LKSGRSEAGARaaASHTGalAGSDAVYDAAFRRAGVIRVDDLEELFDAAEALARQPPPRGRRLAIVTNSGGPGVLAADAL 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 309 WSKNGKLATLSEDTCQKLRDALPEHVDIANPLDLRDDASSEHYVKTLDILLASQDFDALMVIHSPSAAAPGTESAQALIE 388
Cdd:COG1042  321 EDLGLELAELSEETQAALRAVLPPFASVGNPVDITGDADPERYAAALEALLADPNVDAVLVILTPTAMTDPEEVAEALIE 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 389 AVKHHprGKFVslLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPAlPDNLTTNTAEAHN 468
Cdd:COG1042  401 AAKGS--GKPV--LASWMGGDSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPA-SEDFDPDRERARA 475

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 469 LLQQAIAEGATSLDTHEVQPILQAYGLHTLPTWIASDSAEAVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTATEV 548
Cdd:COG1042  476 IIEAALAEGRGVLTEAEAKALLAAYGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRDAEAV 555

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 549 QQAANAIFDRVKMAWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMNLARY 628
Cdd:COG1042  556 RAAFEEILARVRAARPDARIDGVLVQPMVP--GGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNEALARE 633

                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 936194510 629 LVIQGIKNKKIRARSALRPLDIAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASAEEFTALDVTLDIAPFAGD 700
Cdd:COG1042  634 MIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLPEILELDINPLLVVPEGVVAVDARIRLAPPAPP 705
AcCoA-syn-alpha TIGR02717
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it ...
 6-443 2.41e-137

acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.


Pssm-ID: 131764 [Multi-domain]  Cd Length: 447  Bit Score: 416.71  E-value: 2.41e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510    6 LEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVLAWPNINSLPFSPDLAVLCTNASRNLAL 85
Cdd:TIGR02717   1 LEHLFNPKSVAVIGASRDPGKVGYAIMKNLIEGGYKGKIYPVNPKAGEILGVKAYPSVLEIPDPVDLAVIVVPAKYVPQV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510   86 LEALGEKGCKTCIILSAPSAQ--------HAELLACASRYNIRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSA 157
Cdd:TIGR02717  81 VEECGEKGVKGAVVITAGFKEvgeegaelEQELVEIARKYGMRLLGPNCLGIINTHIKLNATFAPTMPKKGGIAFISQSG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  158 AVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEHLSDARRFVSAARSASRNKPILVIKSGR 237
Cdd:TIGR02717 161 ALLTALLDWAEKNGVGFSYFVSLGNKADIDESDLLEYLADDPDTKVILLYLEGIKDGRKFLKTAREISKKKPIVVLKSGT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  238 SPAAQRLL--HTS--AGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMIISNGAAPAALALDELWSKNG 313
Cdd:TIGR02717 241 SEAGAKAAssHTGalAGSDEAYDAAFKQAGVIRADSIEELFDLARLLSNQPLPKGNRVAIITNAGGPGVIATDACEENGL 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  314 KLATLSEDTCQKLRDALPEHVDIANPLDLRDDASSEHYVKTLDILLASQDFDALMVIHSPSAAAPGTESAQALIEAVKHH 393
Cdd:TIGR02717 321 ELAELSEATKNKLRNILPPEASIKNPVDVLGDATPERYAKALKTVAEDENVDGVVVVLTPTAMTDPEEVAKGIIEGAKKS 400

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 936194510  394 PRgkfVSLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYR 443
Cdd:TIGR02717 401 NE---KPVVAGFMGGKSVDPAKRILEENGIPNYTFPERAVKALSALYRYA 447
ATP-grasp_5 pfam13549
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent ...
 472-690 3.84e-89

ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent carboxylate-amine ligase activity.


Pssm-ID: 463918 [Multi-domain]  Cd Length: 221  Bit Score: 282.06  E-value: 3.84e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  472 QAIAEGATSLDTHEVQPILQAYGLHTLPTWIASDSAEAVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTATEVQQA 551
Cdd:pfam13549   1 KALAEGRTVLTEPEAKALLAAYGIPVVPTRLARSPEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRSAEAVRAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  552 ANAIFDRVKMAWPQARIHGLLVQSMANraGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMNLARYLvI 631
Cdd:pfam13549  81 YEEILERVRRYRPDARIEGVLVQPMAP--GGRELIVGVTRDPQFGPVIMFGLGGIAVEVLKDVAFRLPPLNMTLAREM-I 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  632 QGIKNKKIRARSALR-PLDIAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASAEEFTALDV 690
Cdd:pfam13549 158 RRTRAYKLLKGYRGEpPADLDALEDVLVRVSQLVIDFPEIRELDINPLLADEDGVVALDA 217
Succ_CoA_lig pfam13607
Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from ...
 147-280 2.44e-55

Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from Succinyl-CoA ligase alpha subunit and other related enzymes. A conserved histidine is involved in phosphoryl transfer.


Pssm-ID: 433345 [Multi-domain]  Cd Length: 138  Bit Score: 187.29  E-value: 2.44e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  147 RGKLAFISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEHLSDARRFVSAARSASR 226
Cdd:pfam13607   1 PGNIALVSQSGALGAALLDWARSRGIGFSKFVSLGNEADVDFADLLEYLADDPETRVILLYLEGIRDGRRFLRAARRAAR 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 936194510  227 NKPILVIKSGRSPAAQR--LLHT--SAGMDPAWDAAIQRAGLLRVQDTHELFSAVETL 280
Cdd:pfam13607  81 RKPVVVLKAGRSEAGARaaASHTgaLAGSDAVYDAAFRQAGVIRVDDLEELFDAAEAL 138
CoA_binding_2 pfam13380
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 13-132 9.73e-30

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 433162 [Multi-domain]  Cd Length: 116  Bit Score: 114.17  E-value: 9.73e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510   13 KSIAVIGASMKPNRAGYLMMRNLLAGGFngPVLPVTPAWKAVLGVLAWPNINSLPFSPDLAVLCTNASRNLALLEALGEK 92
Cdd:pfam13380   1 KTIAVVGASPNPGRPGYKVARYLLEHGY--PVIPVNPKAKEILGEPVYPSLADPPEPVDLVDVFRPPEAVPEIVEEALAL 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 936194510   93 GCKTCIILsaPSAQHAELLACASRYNIRLLGPNSLGLLAP 132
Cdd:pfam13380  79 GAKAVWLQ--PGIENEEAAAIARAAGIRVVGDRCLGVEHP 116
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 722-874 1.52e-17

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 81.20  E-value: 1.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 722 NGERCLFRPILPEDEPHLQQFISQvtKEDLYYRYFSEIN-EFTHEDLANMTQIDYDREMAFVAVRCKDNhEEILGVTRAI 800
Cdd:COG1670    4 ETERLRLRPLRPEDAEALAELLND--PEVARYLPGPPYSlEEARAWLERLLADWADGGALPFAIEDKED-GELIGVVGLY 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 936194510 801 S-DPDNVDAEFAVLVRSDLKGLGLGRRLMEKLIAYTRDH-GLIRLNGITMPNNRGMVALARKLGFVVDVQLEEGIV 874
Cdd:COG1670   81 DiDRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEElGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALV 156
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
728-871 4.81e-15

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 73.49  E-value: 4.81e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 728 FRPILPEDEPHLQQFISQVTKEDLYyRYFSEinEFTHEDLAN-MTQIDYDREMAFVAVRckdnHEEILGVTRAIS----D 802
Cdd:COG1247    4 IRPATPEDAPAIAAIYNEAIAEGTA-TFETE--PPSEEEREAwFAAILAPGRPVLVAEE----DGEVVGFASLGPfrprP 76

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 936194510 803 PDNVDAEFAVLVRSDLKGLGLGRRLMEKLIAYTRDHGLIRLNGITMPNNRGMVALARKLGFVVDVQLEE 871
Cdd:COG1247   77 AYRGTAEESIYVDPDARGRGIGRALLEALIERARARGYRRLVAVVLADNEASIALYEKLGFEEVGTLPE 145
CoA_binding smart00881
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ...
 9-102 4.05e-14

CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.


Pssm-ID: 214881 [Multi-domain]  Cd Length: 100  Bit Score: 68.69  E-value: 4.05e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510     9 LLRP-KSIAVIGASMKPNRAGYLMMRNLLAGG--FNGPVLP--VTPawkAVLGVLAWPNINSLP--FSPDLAVLCTNASR 81
Cdd:smart00881   1 LLNPnTSVAVVGASGNLGSFGLAVMRNLLEYGtkFVGGVYPgkVGP---KVDGVPVYDSVAEAPeeTGVDVAVIFVPAEA 77

                           90       100
                   ....*....|....*....|.
gi 936194510    82 NLALLEALGEKGCKTCIILSA 102
Cdd:smart00881  78 APDAIDEAIEAGIKGIVVITE 98
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 750-863 7.94e-11

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 60.22  E-value: 7.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  750 DLYYRYFSEinEFTHEDLANMTQIDYDREMAFVAVRckdNHEEILGVTRA--ISDPDNVDAEFAVLVRSDLKGLGLGRRL 827
Cdd:pfam00583   6 ELLSEEFPE--PWPDEPLDLLEDWDEDASEGFFVAE---EDGELVGFASLsiIDDEPPVGEIEGLAVAPEYRGKGIGTAL 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 936194510  828 MEKLIAYTRDHGLIRLNGITMPNNRGMVALARKLGF 863
Cdd:pfam00583  81 LQALLEWARERGCERIFLEVAADNLAAIALYEKLGF 116
YccU COG1832
Predicted CoA-binding protein [General function prediction only];
7-96 6.17e-10

Predicted CoA-binding protein [General function prediction only];


Pssm-ID: 441437 [Multi-domain]  Cd Length: 138  Bit Score: 58.22  E-value: 6.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510   7 EALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNgpVLPVTPAWKAVLGVLAWPNINSLPFSPDLAVLCTNASRNLALL 86
Cdd:COG1832   11 EILKSAKTIAVVGLSPNPERPSYYVAKYLQRHGYR--VIPVNPGAKEILGEKVYASLADIPEPVDIVDVFRRSEAVPEIV 88

                         90
                 ....*....|
gi 936194510  87 EALGEKGCKT 96
Cdd:COG1832   89 DEAIAIGAKV 98
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 725-864 3.54e-07

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 50.42  E-value: 3.54e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  725 RCLFRPILPEDEPHLQQFISQvtKEDLYYRYFSEIN-EFTHEDLANMTQIDYDREMAFVAVRCKDnhEEILGVTRAIS-D 802
Cdd:pfam13302   1 RLLLRPLTEEDAEALFELLSD--PEVMRYGVPWPLTlEEAREWLARIWAADEAERGYGWAIELKD--TGFIGSIGLYDiD 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 936194510  803 PDNVDAEFAVLVRSDLKGLGLGRRLMEKLIAYT-RDHGLIRLNGITMPNNRGMVALARKLGFV 864
Cdd:pfam13302  77 GEPERAELGYWLGPDYWGKGYATEAVRALLEYAfEELGLPRLVARIDPENTASRRVLEKLGFK 139
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 814-865 6.18e-07

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 48.11  E-value: 6.18e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 936194510 814 VRSDLKGLGLGRRLMEKLIAYTRDHGLIRLNGITMPNNRGMVALARKLGFVV 865
Cdd:COG0456   21 VDPEYRGRGIGRALLEAALERARERGARRLRLEVREDNEAAIALYEKLGFEE 72
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
728-865 5.06e-06

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 47.00  E-value: 5.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 728 FRPILPEDEPHLqqfisqvtkEDLYYRYFSEINEfthEDLANMTQIDYDREMAFVAVRckdnHEEILGVTRAISDPDNVD 807
Cdd:COG3153    1 IRPATPEDAEAI---------AALLRAAFGPGRE---AELVDRLREDPAAGLSLVAED----DGEIVGHVALSPVDIDGE 64

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 936194510 808 AEFAVL----VRSDLKGLGLGRRLMEKLIAYTRDHG--LIRLNGitmpnNRGMVALARKLGFVV 865
Cdd:COG3153   65 GPALLLgplaVDPEYRGQGIGRALMRAALEAARERGarAVVLLG-----DPSLLPFYERFGFRP 123
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 761-865 1.04e-05

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 45.81  E-value: 1.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 761 EFTHEDLANMTQIDYDREmaFVAVRCKDnheEILGVTRAISDPDNVdAEFAVL-VRSDLKGLGLGRRLMEKLIAYTRDHG 839
Cdd:COG0454   18 EALDAELKAMEGSLAGAE--FIAVDDKG---EPIGFAGLRRLDDKV-LELKRLyVLPEYRGKGIGKALLEALLEWARERG 91

                         90       100
                 ....*....|....*....|....*...
gi 936194510 840 L--IRLNgiTMPNNRGMVALARKLGFVV 865
Cdd:COG0454   92 CtaLELD--TLDGNPAAIRFYERLGFKE 117
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
792-864 2.14e-05

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 43.74  E-value: 2.14e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 936194510 792 EILGVTRAISDPDNVDAEFAVLVRSDLKGLGLGRRLMEKLIAYTRDHGLIRLNGITMPNNRGMVALARKLGFV 864
Cdd:COG3393    1 ELVAMAGVRAESPGVAEISGVYTHPEYRGRGLASALVAALAREALARGARTPFLYVDADNPAARRLYERLGFR 73
SucD COG0074
Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA ...
 84-280 6.72e-05

Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA synthetase, alpha subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 439844 [Multi-domain]  Cd Length: 288  Bit Score: 45.82  E-value: 6.72e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  84 ALLEALgEKGCKTCIILSA--PSAQHAELLACASRYNIRLLGPNSLGLLAPWQgLNASFSPVPI-KRGKLAFISQSAAVS 160
Cdd:COG0074   80 AILEAI-DAGIKLIVCITEgiPVLDMVRVKRYAKAKGTRLIGPNCPGIITPGE-CKLGIMPGHIfKPGRVGIVSRSGTLT 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 161 NTILDWAQQREMGFSYFIALG-DSL-DIDVDELLDYLARDSKTSAILLYLEHLSDARrfVSAAR--SASRNKPILVIKSG 236
Cdd:COG0074  158 YEAVWQLTQAGLGQSTCVGIGgDPIiGTSFIDVLELFEEDPETEAIVMIGEIGGSAE--EEAAEyiKENMTKPVVAYIAG 235

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 936194510 237 RS-PAAQRLLHTSA----GMDPAWD--AAIQRAGLLRVQDTHELFSAVETL 280
Cdd:COG0074  236 RTaPPGKRMGHAGAiisgGKGTAESkiEALEAAGVPVAESPSEIGELLKKA 286
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
789-873 8.24e-05

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 43.25  E-value: 8.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 789 NHEEILGVTRaISDPDNVDAEFA-VLVRSDLKGLGLGRRLMEKLIAYTRDHGL--IRLNGITmpnnrGMVALARKLGFVV 865
Cdd:COG2153   41 DDGELVATAR-LLPPGDGEAKIGrVAVLPEYRGQGLGRALMEAAIEEARERGArrIVLSAQA-----HAVGFYEKLGFVP 114

                         90
                 ....*....|
gi 936194510 866 --DVQLEEGI 873
Cdd:COG2153  115 vgEEFLEAGI 124
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 776-865 2.98e-04

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 40.52  E-value: 2.98e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510  776 DREMAFVAvrckDNHEEILGVTRAISDPDNVD-AEFAVLVRSDLKGLGLGRRLMEKLIAYTRDHGLIRlngITMPNNRGM 854
Cdd:pfam13508   1 PGGRFFVA----EDDGKIVGFAALLPLDDEGAlAELRLAVHPEYRGQGIGRALLEAAEAAAKEGGIKL---LELETTNRA 73

                          90
                  ....*....|.
gi 936194510  855 VALARKLGFVV 865
Cdd:pfam13508  74 AAFYEKLGFEE 84
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 728-865 3.66e-04

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 41.52  E-value: 3.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 936194510 728 FRPILPEDEPHLQQFISQvtkedlyYRYFSEINEFthedlanmtqidydremaFVAVRckdnHEEILGVTRAISDPDNVd 807
Cdd:COG1246    3 IRPATPDDVPAILELIRP-------YALEEEIGEF------------------WVAEE----DGEIVGCAALHPLDEDL- 52

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 936194510 808 AEFA-VLVRSDLKGLGLGRRLMEKLIAYTRDHGLIRLNGITmpnNRGMVALARKLGFVV 865
Cdd:COG1246   53 AELRsLAVHPDYRGRGIGRRLLEALLAEARELGLKRLFLLT---TSAAIHFYEKLGFEE 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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