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Conserved domains on  [gi|937116917|ref|WP_054554356|]
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MULTISPECIES: SPOR domain-containing protein [Pseudoalteromonas]

Protein Classification

SPOR domain-containing protein( domain architecture ID 10523510)

SPOR domain-containing protein similar to Pseudomonas aeruginosa Endolytic peptidoglycan transglycosylase RlpA and Bacillus subtilis sporulation-specific N-acetylmuramoyl-L-alanine amidase

CATH:  3.30.70.1070
Gene Ontology:  GO:0042834|GO:0016020
PubMed:  26305949
SCOP:  4002705

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SPOR pfam05036
SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell ...
 79-159 6.62e-07

SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell division site by binding to denuded glycan strands that lack stem peptides. This 70 residue domain is composed of two 35 residue repeats found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This domain is involved in binding peptidoglycan. Two tandem repeats fold into a pseudo-2-fold symmetric single-domain structure containing numerous contacts between the repeats. FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localizes to the septum ring complex.


:

Pssm-ID: 461531 [Multi-domain]  Cd Length: 76  Bit Score: 44.66  E-value: 6.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937116917   79 PNYTFALQLASVSSETAIEvtfhKMAKQApsifQGKPILNVEVADVHDRTFYRLKFGGYKYLKNAKADCAAIKR-QGIDC 157
Cdd:pfam05036   1 ASGGYYVQLGAFSNEANAE----ALAAKL----RAKGFAAYVAVTSKGGGLYRVRVGPFASREEARAALKKLKAlAGLSP 72


                  ..
gi 937116917  158 WV 159
Cdd:pfam05036  73 FV 74
 
Name Accession Description Interval E-value
SPOR pfam05036
SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell ...
 79-159 6.62e-07

SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell division site by binding to denuded glycan strands that lack stem peptides. This 70 residue domain is composed of two 35 residue repeats found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This domain is involved in binding peptidoglycan. Two tandem repeats fold into a pseudo-2-fold symmetric single-domain structure containing numerous contacts between the repeats. FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localizes to the septum ring complex.


Pssm-ID: 461531 [Multi-domain]  Cd Length: 76  Bit Score: 44.66  E-value: 6.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937116917   79 PNYTFALQLASVSSETAIEvtfhKMAKQApsifQGKPILNVEVADVHDRTFYRLKFGGYKYLKNAKADCAAIKR-QGIDC 157
Cdd:pfam05036   1 ASGGYYVQLGAFSNEANAE----ALAAKL----RAKGFAAYVAVTSKGGGLYRVRVGPFASREEARAALKKLKAlAGLSP 72


                  ..
gi 937116917  158 WV 159
Cdd:pfam05036  73 FV 74
FtsN COG3087
Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];
59-159 5.78e-06

Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442321 [Multi-domain]  Cd Length: 198  Bit Score: 44.62  E-value: 5.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937116917  59 QSTATQKNTLATAAILAPTKPnytFALQLASVSSETAIEvtfhKMAKQApsIFQGKPIlNVEVADVHDRTFYRLKFGGYK 138
Cdd:COG3087  104 AAAPAGMAKKEAAAAPAAKKP---YYVQVGAFRSRANAE----RLRARL--ALLGLEA-RVVEVEVGGGTWYRVRVGPFS 173

                         90       100
                 ....*....|....*....|.
gi 937116917 139 YLKNAKADCAAIKRQGIDCWV 159
Cdd:COG3087  174 SRAEAEKAREKLKAAGIDALV 194
 
Name Accession Description Interval E-value
SPOR pfam05036
SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell ...
 79-159 6.62e-07

SPOR domain; Bacterial SPOR domains bind peptidoglycan (PG) and target proteins to the cell division site by binding to denuded glycan strands that lack stem peptides. This 70 residue domain is composed of two 35 residue repeats found in proteins involved in sporulation and cell division such as FtsN, DedD, and CwlM. This domain is involved in binding peptidoglycan. Two tandem repeats fold into a pseudo-2-fold symmetric single-domain structure containing numerous contacts between the repeats. FtsN is an essential cell division protein with a simple bitopic topology, a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain. These repeats lay at the periplasmic C-terminus. FtsN localizes to the septum ring complex.


Pssm-ID: 461531 [Multi-domain]  Cd Length: 76  Bit Score: 44.66  E-value: 6.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937116917   79 PNYTFALQLASVSSETAIEvtfhKMAKQApsifQGKPILNVEVADVHDRTFYRLKFGGYKYLKNAKADCAAIKR-QGIDC 157
Cdd:pfam05036   1 ASGGYYVQLGAFSNEANAE----ALAAKL----RAKGFAAYVAVTSKGGGLYRVRVGPFASREEARAALKKLKAlAGLSP 72


                  ..
gi 937116917  158 WV 159
Cdd:pfam05036  73 FV 74
FtsN COG3087
Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];
59-159 5.78e-06

Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442321 [Multi-domain]  Cd Length: 198  Bit Score: 44.62  E-value: 5.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937116917  59 QSTATQKNTLATAAILAPTKPnytFALQLASVSSETAIEvtfhKMAKQApsIFQGKPIlNVEVADVHDRTFYRLKFGGYK 138
Cdd:COG3087  104 AAAPAGMAKKEAAAAPAAKKP---YYVQVGAFRSRANAE----RLRARL--ALLGLEA-RVVEVEVGGGTWYRVRVGPFS 173

                         90       100
                 ....*....|....*....|.
gi 937116917 139 YLKNAKADCAAIKRQGIDCWV 159
Cdd:COG3087  174 SRAEAEKAREKLKAAGIDALV 194
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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