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Conserved domains on  [gi|937127111|ref|WP_054562241|]
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MULTISPECIES: phosphopyruvate hydratase [unclassified Pseudoalteromonas]

Protein Classification

phosphopyruvate hydratase( domain architecture ID 11414960)

phosphopyruvate hydratase (enolase) catalyzes the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways

CATH:  3.20.20.120|3.30.390.10
EC:  4.2.1.11
Gene Ontology:  GO:0004634|GO:0000015|GO:0006096|GO:0000287
PubMed:  8994873|8605183
SCOP:  3001064|3000476

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-431 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


:

Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 853.54  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   1 MSEIVKVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLKAVGYINNEIAEALK 80
Cdd:COG0148    1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  81 GQNAVDQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIADLNGtsgvYSMPLPMMNIINGGEHA 160
Cdd:COG0148   81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNA----KTLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 161 DNSVDIQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAEGHSTSVGDEGGFAPNLESNEAALAAIKVAVANAGYELGKD 240
Cdd:COG0148  157 DNNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 241 ITLALDCAASEFYDKeaNIYDLKGEGKKFTSEEFNHFLKGLTEQYPIVSIEDGLDESDWDGFAHQTQLIGDKVQLVGDDL 320
Cdd:COG0148  237 IALALDVAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDL 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 321 FVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLSR 400
Cdd:COG0148  315 FVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSR 394

                        410       420       430
                 ....*....|....*....|....*....|.
gi 937127111 401 SDRIAKYNQLLRIEEVLGEKAPYNGLKEVKG 431
Cdd:COG0148  395 SERVAKYNQLLRIEEELGDAARYAGRSAFKR 425
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-431 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 853.54  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   1 MSEIVKVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLKAVGYINNEIAEALK 80
Cdd:COG0148    1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  81 GQNAVDQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIADLNGtsgvYSMPLPMMNIINGGEHA 160
Cdd:COG0148   81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNA----KTLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 161 DNSVDIQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAEGHSTSVGDEGGFAPNLESNEAALAAIKVAVANAGYELGKD 240
Cdd:COG0148  157 DNNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 241 ITLALDCAASEFYDKeaNIYDLKGEGKKFTSEEFNHFLKGLTEQYPIVSIEDGLDESDWDGFAHQTQLIGDKVQLVGDDL 320
Cdd:COG0148  237 IALALDVAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDL 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 321 FVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLSR 400
Cdd:COG0148  315 FVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSR 394

                        410       420       430
                 ....*....|....*....|....*....|.
gi 937127111 401 SDRIAKYNQLLRIEEVLGEKAPYNGLKEVKG 431
Cdd:COG0148  395 SERVAKYNQLLRIEEELGDAARYAGRSAFKR 425
eno PRK00077
enolase; Provisional
 1-432 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 817.79  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   1 MSEIVKVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLKAVGYINNEIAEALK 80
Cdd:PRK00077   1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  81 GQNAVDQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIadlnGTSGVYSMPLPMMNIINGGEHA 160
Cdd:PRK00077  81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYL----GGPNAKVLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 161 DNSVDIQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAEGHSTSVGDEGGFAPNLESNEAALAAIKVAVANAGYELGKD 240
Cdd:PRK00077 157 DNNVDIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 241 ITLALDCAASEFYDKEanIYDLKGEGkkFTSEEFNHFLKGLTEQYPIVSIEDGLDESDWDGFAHQTQLIGDKVQLVGDDL 320
Cdd:PRK00077 237 IALALDCAASEFYKDG--KYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDL 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 321 FVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLSR 400
Cdd:PRK00077 313 FVTNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSR 392

                        410       420       430
                 ....*....|....*....|....*....|..
gi 937127111 401 SDRIAKYNQLLRIEEVLGEKAPYNGLKEVKGQ 432
Cdd:PRK00077 393 SERIAKYNQLLRIEEELGDAARYAGKKAFKNL 424
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 4-432 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 720.68  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111    4 IVKVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLKAVGYINNEIAEALKGQN 83
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   84 AVDQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIADLNGtsgvYSMPLPMMNIINGGEHADNS 163
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNA----YVLPVPMMNIINGGAHADNN 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  164 VDIQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAEGHSTSVGDEGGFAPNLESNEAALAAIKVAVANAGYELGKDITL 243
Cdd:TIGR01060 157 LDFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVAL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  244 ALDCAASEFYDKEANIYDLKGEGKKFTSEEFNHFLKGLTEQYPIVSIEDGLDESDWDGFAHQTQLIGDKVQLVGDDLFVT 323
Cdd:TIGR01060 237 ALDCAASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVT 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  324 NTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLSRSDR 403
Cdd:TIGR01060 317 NTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSER 396

                         410       420
                  ....*....|....*....|....*....
gi 937127111  404 IAKYNQLLRIEEVLGEKAPYNGLKEVKGQ 432
Cdd:TIGR01060 397 IAKYNQLLRIEEELGDSARYAGKNSFYRF 425
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 6-415 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 706.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   6 KVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLKAVGYINNEIAEALKGQNAV 85
Cdd:cd03313    1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  86 DQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIADLNGtsgvYSMPLPMMNIINGGEHADNSVD 165
Cdd:cd03313   81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAA----YVLPVPMFNVINGGAHAGNKLD 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 166 IQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAEG--HSTSVGDEGGFAPNLESNEAALAAIKVAVANAGYELGKDITL 243
Cdd:cd03313  157 FQEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAI 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 244 ALDCAASEFYDKEANIYDlKGEGKKFTSEEFNHFLKGLTEQYPIVSIEDGLDESDWDGFAHQTQLIGDKVQLVGDDLFVT 323
Cdd:cd03313  237 ALDVAASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVT 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 324 NTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLSRSDR 403
Cdd:cd03313  316 NPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSER 395

                        410
                 ....*....|..
gi 937127111 404 IAKYNQLLRIEE 415
Cdd:cd03313  396 TAKYNQLLRIEE 407
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
144-432 9.44e-160

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 452.32  E-value: 9.44e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  144 YSMPLPMMNIINGGEHADNSVDIQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAEGHS--TSVGDEGGFAPNLESNEA 221
Cdd:pfam00113   2 YVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGQsaTNVGDEGGFAPNLQSNKE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  222 ALAAIKVAVANAGYELgkDITLALDCAASEFYDKEANIYDLKGEG------KKFTSEEFNHFLKGLTEQYPIVSIEDGLD 295
Cdd:pfam00113  82 ALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPFD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  296 ESDWDGFAHQTQLIGDKVQLVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGE 375
Cdd:pfam00113 160 EDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGE 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 937127111  376 TEDATIADLAVGTAAGQIKTGSLSRSDRIAKYNQLLRIEEVLGEKAPYNGLKEVKGQ 432
Cdd:pfam00113 240 TEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
 
Name Accession Description Interval E-value
Eno COG0148
Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: ...
 1-431 0e+00

Enolase [Carbohydrate transport and metabolism]; Enolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439918 [Multi-domain]  Cd Length: 426  Bit Score: 853.54  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   1 MSEIVKVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLKAVGYINNEIAEALK 80
Cdd:COG0148    1 MSRIEDVHAREILDSRGNPTVEVEVTLEDGAVGRAAVPSGASTGSHEAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  81 GQNAVDQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIADLNGtsgvYSMPLPMMNIINGGEHA 160
Cdd:COG0148   81 GMDATDQRAIDRAMIELDGTPNKSRLGANAILGVSLAVAKAAAAALGLPLYRYLGGVNA----KTLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 161 DNSVDIQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAEGHSTSVGDEGGFAPNLESNEAALAAIKVAVANAGYELGKD 240
Cdd:COG0148  157 DNNVDIQEFMIMPVGAPSFSEALRMGAEVFHALKKVLKEKGLSTAVGDEGGFAPNLKSNEEALELILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 241 ITLALDCAASEFYDKeaNIYDLKGEGKKFTSEEFNHFLKGLTEQYPIVSIEDGLDESDWDGFAHQTQLIGDKVQLVGDDL 320
Cdd:COG0148  237 IALALDVAASEFYKD--GKYHLKGEGKELTSEEMIDYYADLVDKYPIVSIEDGLAEDDWDGWKLLTEKLGDKVQLVGDDL 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 321 FVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLSR 400
Cdd:COG0148  315 FVTNPKRLKKGIEEGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSPSR 394

                        410       420       430
                 ....*....|....*....|....*....|.
gi 937127111 401 SDRIAKYNQLLRIEEVLGEKAPYNGLKEVKG 431
Cdd:COG0148  395 SERVAKYNQLLRIEEELGDAARYAGRSAFKR 425
eno PRK00077
enolase; Provisional
 1-432 0e+00

enolase; Provisional


Pssm-ID: 234617 [Multi-domain]  Cd Length: 425  Bit Score: 817.79  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   1 MSEIVKVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLKAVGYINNEIAEALK 80
Cdd:PRK00077   1 MSKIEDIIAREILDSRGNPTVEVEVTLEDGAFGRAAVPSGASTGEREAVELRDGDKSRYLGKGVLKAVENVNEEIAPALI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  81 GQNAVDQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIadlnGTSGVYSMPLPMMNIINGGEHA 160
Cdd:PRK00077  81 GLDALDQRAIDKAMIELDGTPNKSKLGANAILGVSLAVAKAAADSLGLPLYRYL----GGPNAKVLPVPMMNIINGGAHA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 161 DNSVDIQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAEGHSTSVGDEGGFAPNLESNEAALAAIKVAVANAGYELGKD 240
Cdd:PRK00077 157 DNNVDIQEFMIMPVGAPSFKEALRMGAEVFHTLKKVLKEKGLSTAVGDEGGFAPNLKSNEEALDLILEAIEKAGYKPGED 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 241 ITLALDCAASEFYDKEanIYDLKGEGkkFTSEEFNHFLKGLTEQYPIVSIEDGLDESDWDGFAHQTQLIGDKVQLVGDDL 320
Cdd:PRK00077 237 IALALDCAASEFYKDG--KYVLEGEG--LTSEEMIDYLAELVDKYPIVSIEDGLDENDWEGWKLLTEKLGDKVQLVGDDL 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 321 FVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLSR 400
Cdd:PRK00077 313 FVTNTKRLKKGIEKGAANSILIKVNQIGTLTETLDAIELAKRAGYTAVVSHRSGETEDTTIADLAVATNAGQIKTGSLSR 392

                        410       420       430
                 ....*....|....*....|....*....|..
gi 937127111 401 SDRIAKYNQLLRIEEVLGEKAPYNGLKEVKGQ 432
Cdd:PRK00077 393 SERIAKYNQLLRIEEELGDAARYAGKKAFKNL 424
eno TIGR01060
phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis ...
 4-432 0e+00

phosphopyruvate hydratase; Alternate name: enolase [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 213580 [Multi-domain]  Cd Length: 425  Bit Score: 720.68  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111    4 IVKVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLKAVGYINNEIAEALKGQN 83
Cdd:TIGR01060   1 IVDIRAREILDSRGNPTVEVEVILEDGTFGRAAVPSGASTGEREALELRDGDKKRYLGKGVLKAVENVNEIIAPELIGMD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   84 AVDQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIADLNGtsgvYSMPLPMMNIINGGEHADNS 163
Cdd:TIGR01060  81 ATDQREIDQILIELDGTPNKSKLGANAILGVSMAVAKAAADSLGLPLYRYLGGFNA----YVLPVPMMNIINGGAHADNN 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  164 VDIQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAEGHSTSVGDEGGFAPNLESNEAALAAIKVAVANAGYELGKDITL 243
Cdd:TIGR01060 157 LDFQEFMIMPVGAPSFREALRMGAEVFHALKKLLKEKGLATGVGDEGGFAPNLASNEEALEIIVEAIEKAGYKPGEDVAL 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  244 ALDCAASEFYDKEANIYDLKGEGKKFTSEEFNHFLKGLTEQYPIVSIEDGLDESDWDGFAHQTQLIGDKVQLVGDDLFVT 323
Cdd:TIGR01060 237 ALDCAASEFYDEEDGKYVYKGENKQLTSEEMIEYYEELVEKYPIISIEDGLSEEDWEGWAELTKRLGDKVQIVGDDLFVT 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  324 NTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLSRSDR 403
Cdd:TIGR01060 317 NTEILREGIEMGVANSILIKPNQIGTLTETLDAIELAKKAGYTAVISHRSGETEDTTIADLAVATNAGQIKTGSLSRSER 396

                         410       420
                  ....*....|....*....|....*....
gi 937127111  404 IAKYNQLLRIEEVLGEKAPYNGLKEVKGQ 432
Cdd:TIGR01060 397 IAKYNQLLRIEEELGDSARYAGKNSFYRF 425
enolase cd03313
Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of ...
 6-415 0e+00

Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions.


Pssm-ID: 239429 [Multi-domain]  Cd Length: 408  Bit Score: 706.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   6 KVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLKAVGYINNEIAEALKGQNAV 85
Cdd:cd03313    1 KIKAREILDSRGNPTVEVEVTTEDGGVGRAAVPSGASTGEHEAVELRDGDKSRYLGKGVLKAVKNVNEIIAPALIGMDVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  86 DQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIADLNGtsgvYSMPLPMMNIINGGEHADNSVD 165
Cdd:cd03313   81 DQRAIDKLLIELDGTPNKSKLGANAILGVSLAVAKAAAAALGLPLYRYLGGLAA----YVLPVPMFNVINGGAHAGNKLD 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 166 IQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAEG--HSTSVGDEGGFAPNLESNEAALAAIKVAVANAGYELGKDITL 243
Cdd:cd03313  157 FQEFMIVPVGAPSFSEALRMGAEVYHTLKKVLKKKGglLATNVGDEGGFAPNLSSNEEALDLLVEAIEKAGYEPGKKIAI 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 244 ALDCAASEFYDKEANIYDlKGEGKKFTSEEFNHFLKGLTEQYPIVSIEDGLDESDWDGFAHQTQLIGDKVQLVGDDLFVT 323
Cdd:cd03313  237 ALDVAASEFYDEGKYVYD-SDEGKKLTSEELIDYYKELVKKYPIVSIEDPFDEDDWEGWAKLTAKLGDKIQIVGDDLFVT 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 324 NTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIKTGSLSRSDR 403
Cdd:cd03313  316 NPERLKKGIEKKAANALLIKVNQIGTLTETIEAIKLAKKNGYGVVVSHRSGETEDTFIADLAVALGAGQIKTGAPCRSER 395

                        410
                 ....*....|..
gi 937127111 404 IAKYNQLLRIEE 415
Cdd:cd03313  396 TAKYNQLLRIEE 407
PTZ00081 PTZ00081
enolase; Provisional
 1-425 0e+00

enolase; Provisional


Pssm-ID: 240259 [Multi-domain]  Cd Length: 439  Bit Score: 564.29  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   1 MSEIVKVIGREIMDSRGNPTVEADVHLADGSWgRAAAPSGASTGTREALELRDGDKARYLGKGVLKAVGYINNEIAEALK 80
Cdd:PTZ00081   1 MSTIKSIKAREILDSRGNPTVEVDLTTEKGVF-RAAVPSGASTGIYEALELRDGDKSRYLGKGVLKAVENVNEIIAPALI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  81 GQNAVDQKAVDQVMLD-LDGTEN-----KEKLGANAILAVSLATAKAAANSKGVELYEHIADLNGT-SGVYSMPLPMMNI 153
Cdd:PTZ00081  80 GKDVTDQKKLDKLMVEqLDGTKNewgwcKSKLGANAILAVSMAVARAAAAAKGVPLYKYLAQLAGKpTDKFVLPVPCFNV 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 154 INGGEHADNSVDIQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAE-GHS-TSVGDEGGFAPNLESNEAALAAIKVAVA 231
Cdd:PTZ00081 160 INGGKHAGNKLAFQEFMIAPVGAPSFKEALRMGAEVYHSLKSVIKKKyGLDaTNVGDEGGFAPNIKDPEEALDLLVEAIK 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 232 NAGYElGKdITLALDCAASEFYDKEANIYDL------KGEGKKFTSEEFNHFLKGLTEQYPIVSIEDGLDESDWDGFAHQ 305
Cdd:PTZ00081 240 KAGYE-GK-VKICMDVAASEFYDKEKKVYDLdfknpnNDKSNKLTGEELVELYLDLVKKYPIVSIEDPFDQDDWEAYAKL 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 306 TQLIGDKVQLVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLA 385
Cdd:PTZ00081 318 TAAIGQKVQIVGDDLLVTNPTRIKKAIEKKACNALLLKVNQIGTVTEAIEAAKLAQKNGWGVMVSHRSGETEDTFIADLV 397

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|
gi 937127111 386 VGTAAGQIKTGSLSRSDRIAKYNQLLRIEEVLGEKAPYNG 425
Cdd:PTZ00081 398 VGLGTGQIKTGAPCRSERLAKYNQLLRIEEELGSNAVYAG 437
PLN00191 PLN00191
enolase
 1-425 0e+00

enolase


Pssm-ID: 215095 [Multi-domain]  Cd Length: 457  Bit Score: 545.07  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   1 MSEIVKVIGREIMDSRGNPTVEADVHLADGsWGRAAAPSGASTGTREALELRDGDKaRYLGKGVLKAVGYINNEIAEALK 80
Cdd:PLN00191  25 MATITKVKARQIIDSRGNPTVEVDLHTSKG-MFRAAVPSGASTGIYEALELRDGDK-DYLGKGVLKAVKNVNEIIAPALI 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  81 GQNAVDQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIADLNGTSGVySMPLPMMNIINGGEHA 160
Cdd:PLN00191 103 GMDPTDQTQIDNFMLELDGTPNKGKLGANAILAVSLAVCKAGAAEKGVPLYKHIADLAGNKKL-VLPVPAFNVINGGSHA 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 161 DNSVDIQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAE--GHSTSVGDEGGFAPNLESNEAALAAIKVAVANAGYElG 238
Cdd:PLN00191 182 GNKLAMQEFMILPVGASSFKEAMQMGSEVYHHLKAVIKKKygQDACNVGDEGGFAPNIQDNKEGLELLKEAIEKAGYT-G 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 239 KdITLALDCAASEFYDKEaNIYDL------KGEGKKFTSEEFNHFLKGLTEQYPIVSIEDGLDESDWDGFAHQTQLigDK 312
Cdd:PLN00191 261 K-IKIGMDVAASEFYTKD-KKYDLdfkeenNDGSNKKSGDELIDLYKEFVSDYPIVSIEDPFDQDDWEHWAKLTSL--ED 336

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 313 VQLVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQ 392
Cdd:PLN00191 337 VQIVGDDLLVTNPKRVAKAIQEKACNALLLKVNQIGTVTESIEAVKMSKAAGWGVMTSHRSGETEDSFIADLAVGLATGQ 416

                        410       420       430
                 ....*....|....*....|....*....|...
gi 937127111 393 IKTGSLSRSDRIAKYNQLLRIEEVLGEKAPYNG 425
Cdd:PLN00191 417 IKTGAPCRSERLAKYNQLLRIEEELGDEAVYAG 449
Enolase_C pfam00113
Enolase, C-terminal TIM barrel domain;
144-432 9.44e-160

Enolase, C-terminal TIM barrel domain;


Pssm-ID: 395063  Cd Length: 296  Bit Score: 452.32  E-value: 9.44e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  144 YSMPLPMMNIINGGEHADNSVDIQEFMIQPVGATNFREALRMGAEVFHSLAKVLKAEGHS--TSVGDEGGFAPNLESNEA 221
Cdd:pfam00113   2 YVLPVPMMNVINGGSHAGNNLAFQEFMILPTGAPSFSEAMRMGAEVYHHLKSVLKAKYGQsaTNVGDEGGFAPNLQSNKE 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  222 ALAAIKVAVANAGYELgkDITLALDCAASEFYDKEANIYDLKGEG------KKFTSEEFNHFLKGLTEQYPIVSIEDGLD 295
Cdd:pfam00113  82 ALDLIVEAIEKAGYKG--KIKIAMDVASSEFYNKKDGKYDLDFKGeksdksKKLTSAQLADLYEELVKKYPIVSIEDPFD 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  296 ESDWDGFAHQTQLIGDKVQLVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGE 375
Cdd:pfam00113 160 EDDWEAWKYLTERLGDKVQIVGDDLTVTNPKRLKTAIEKKIANALLLKVNQIGSLTESIAAVKMAKDAGWGVMVSHRSGE 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 937127111  376 TEDATIADLAVGTAAGQIKTGSLSRSDRIAKYNQLLRIEEVLGEKAPYNGLKEVKGQ 432
Cdd:pfam00113 240 TEDTTIADLAVGLNAGQIKTGAPCRSERLAKYNQLLRIEEELGSEAKYAGRSFRKPL 296
Enolase_N pfam03952
Enolase, N-terminal domain;
4-134 2.49e-83

Enolase, N-terminal domain;


Pssm-ID: 461105 [Multi-domain]  Cd Length: 131  Bit Score: 251.53  E-value: 2.49e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111    4 IVKVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKARYLGKGVLKAVGYINNEIAEALKGQN 83
Cdd:pfam03952   1 ITKVKAREILDSRGNPTVEVEVTLEDGTFGRAAVPSGASTGEHEAVELRDGDKSRYGGKGVLKAVENVNEIIAPALIGMD 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 937127111   84 AVDQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHI 134
Cdd:pfam03952  81 ATDQRAIDRALIELDGTENKSKLGANAILGVSLAVAKAAAAALGLPLYRYL 131
PRK08350 PRK08350
hypothetical protein; Provisional
 1-420 2.12e-20

hypothetical protein; Provisional


Pssm-ID: 169397 [Multi-domain]  Cd Length: 341  Bit Score: 91.79  E-value: 2.12e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111   1 MSEIVKVIGREIMDSRGNPTVEADVhLADGSWGRAAAPSgastgtrealelrDGDKARYLGKGvLKAVGYINNEIAEALK 80
Cdd:PRK08350   1 MTVIENIIGRVAVLRGGKYSVEVDV-ITDSGFGRFAAPI-------------DENPSLYIAEA-HRAVSEVDEIIGPELI 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  81 GQNAVDQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIadlnGTSGVYSMPLPMMNIINgGEHA 160
Cdd:PRK08350  66 GFDASEQELIDSYLWEIDGTEDFSHIGANTALAVSVAVAKAAANSKNMPLYSYI----GGTFTTELPVPILEFAE-DENF 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 161 DNSVDIQEFMiqpvgatnfrealrMGAEVFHSLAKVLKaeghstsvgdeggfapnlESNEAALAAIKVAVANAGYELGKD 240
Cdd:PRK08350 141 EYYVLVRDLM--------------EITDVVDAVNKILE------------------NSKEVSLEGLSKASEKAGDELGLE 188

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 241 ITLALdcaasefydkeaniydlkGEGKKFTSEEfnhfLKGLTEQYPIVSIEDGLDESDWdgfahqTQLIGDK--VQLVGD 318
Cdd:PRK08350 189 VALGI------------------AQKREMETEK----VLNLVEDNNIAYIKPIGDEELF------LELIAGThgVFIDGE 240

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 319 DLFVTNTKILKRgidngIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSGETEDATIADLAVGTAAGQIktgsL 398
Cdd:PRK08350 241 YLFRTRNILDRR-----YYNALSIKPINLGTLTDLYNLVNDVKSERITPILAEAKYESADEALPHLAVGLRCPAM----L 311

                        410       420
                 ....*....|....*....|..
gi 937127111 399 SRSDRIAKYNQLLRIEEVLGEK 420
Cdd:PRK08350 312 IHKDSVEKINELNRIAEDLGER 333
enolase_like cd00308
Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is ...
 218-388 4.39e-11

Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion. Enolase superfamily contains different enzymes, like enolases, glutarate-, fucanate- and galactonate dehydratases, o-succinylbenzoate synthase, N-acylamino acid racemase, L-alanine-DL-glutamate epimerase, mandelate racemase, muconate lactonizing enzyme and 3-methylaspartase.


Pssm-ID: 238188 [Multi-domain]  Cd Length: 229  Bit Score: 62.34  E-value: 4.39e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 218 SNEAALAAIKVAVanagyelGKDITLALDCAASEFYdKEAniydLKgegkkftseefnhFLKGLtEQYPIVSIEDGLDES 297
Cdd:cd00308   79 GSIERVRAVREAF-------GPDARLAVDANGAWTP-KEA----IR-------------LIRAL-EKYGLAWIEEPCAPD 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 298 DWDGFAHQTQLIGdkVQLVGDDLFVTNTKILkRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTAVISHRSG-ET 376
Cdd:cd00308  133 DLEGYAALRRRTG--IPIAADESVTTVDDAL-EALELGAVDILQIKPTRVGGLTESRRAADLAEAFGIRVMVHGTLEsSI 209

                        170
                 ....*....|..
gi 937127111 377 EDATIADLAVGT 388
Cdd:cd00308  210 GTAAALHLAAAL 221
PTZ00378 PTZ00378
hypothetical protein; Provisional
 84-417 3.94e-09

hypothetical protein; Provisional


Pssm-ID: 173571 [Multi-domain]  Cd Length: 518  Bit Score: 58.35  E-value: 3.94e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111  84 AVDQKAVDQVMLDLDGTENKEKLGANAILAVSLATAKAAANSKGVELYEHIADLNGTSG---VYSMPLPMMNIINGGEHA 160
Cdd:PTZ00378 124 ARDQREFDSTLRAALSTSPLANVGSAVQWALSIVASLAAARCRSVPLFQYLRALFGSLTsveTFSMPQLCITFFGPGNPS 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 161 DNSVDIQEFMIQPV--GATNFREALRMGAEVFHSLAKVlkaegHSTSVGDEGGFAPNLESNEA-ALAAIKVAVANAGYEL 237
Cdd:PTZ00378 204 TARLALKSVLFSPVmpSGTVLRERMQKIFAAFHHFCQS-----HNSSVRSDGSLHWDGFANLTdAVKLATEALRAVQLTP 278

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 238 GKDITLALDCAASEFYDKEANIYDL------KGEGKKF----------TSEEFNHFLKGLTEQYP--IVSIEDglDESDW 299
Cdd:PTZ00378 279 GTDVCLGLRMAASTTRVPATAVADGgawkeaKDDCEVLyslfpgepdvTGDQLSEYVREQLQAVPdiVVYVED--THCDE 356

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937127111 300 DGFAHQ--TQLIGDKVQLVGDDLFV-TNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAK-DAGFTAVISHRSGE 375
Cdd:PTZ00378 357 DTFGLQrlQAALGDSIVLSGVDVYArSEYKKVESGLRGLWTSNIVLNPCAIGTLSDVVEIVRAVGeDEGRAVTVLVQTLA 436

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 937127111 376 TEDATIADLAVGTAAGQIKTGSLSRSDRIAKYNQLLRIEEVL 417
Cdd:PTZ00378 437 GNAATAAHLAVAMGARFLCSGGLFSAHQCEVVSQLASRQDEL 478
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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