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Conserved domains on  [gi|940641997|ref|WP_055014955|]
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MULTISPECIES: TonB-dependent receptor [Pseudoalteromonas]

Protein Classification

TonB-dependent receptor( domain architecture ID 10613439)

TonB dependent receptor having a carboxypeptidase regulatory-like domain, may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0055085|GO:0015267|GO:0015891
PubMed:  12409204

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
90-640 4.76e-32

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


:

Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 133.06  E-value: 4.76e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   90 SVRVSLGANAKASFDLAQVSDSGPEVIqVLGARISSIDLTTADSGLVITDAEIDRMPInRDLTSVALLAPG---AVKGDS 166
Cdd:COG4771     5 SLLLLLALAAQAADALAEDATELEEVV-VTATRTEQSLSDAPASVSVITAEEIEKLGA-TDLADALRLLPGvsvTRSGGR 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  167 AFGNTASFGGSSVAENACYINGLEVTNTRQGLGCG--EVPFEFYDQFQVKTGGYSAKFG-RATGGTINTTTKSGTNEWEF 243
Cdd:COG4771    83 GGSSGISIRGLGGDRVLVLIDGVPVNNPALGGGGDlsYIPPDDIERIEVIRGPASALYGsDAIGGVINIITKKPTDELEG 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  244 aavvqfqpdslqeEGSISRGNNGAGQIfrdesldtdsktDVTISAGGPliEDTLFFYGLINPRDTESTYTWGGDEFSPND 323
Cdd:COG4771   163 -------------SVSLGYGSNGNGTY------------SGSLSLGGP--GDKLSFLLSGSYRDRDGYLDYRNGGFVGNS 215
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  324 QYRNESAsggdnlfwGGKLDWDINENHRLSYFAYSNRRDIERSVYEYNNG-TVGDRIDGAILKRGGEAQSLSYTGVLTED 402
Cdd:COG4771   216 GYERYNL--------NAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTeISSDNAGDRDTTTDRGNYSLRYNGDLGDN 287
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  403 LVVTAmagnikteyetqsenlvcpSITDSRGTANPITGCGAGGSFGANNDENTQYRLDVEYVWND-HEITFGIDYQErks 481
Cdd:COG4771   288 LDLSL-------------------YYSRTDRDSTNGSLGGSTGSFSDSDDTTYGLELDLTYPLGGnHTLTLGAEYRY--- 345
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  482 enisspigghsydyrtladngswqadngaltnntgaalDYVEDRIFDGGGSFESELTAYYIEDQWQVTEDFSVKVGLRID 561
Cdd:COG4771   346 --------------------------------------DDLDSSSFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLRYD 387
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 940641997  562 EFDSWGTTGKLLTSfetdiaPRLGFTWDPtgTGDTKVYGTYGRYylpvanntiFRAASgVSDITTAYTYTGVDSQTGAP 640
Cdd:COG4771   388 YYSTFGASNYTAFS------PRLGLRYDL--SDNLTLRASYGRG---------FRAPS-LAELYGSGTGTPGRYVLGNP 448
CarboxypepD_reg pfam13620
Carboxypeptidase regulatory-like domain;
40-105 3.25e-07

Carboxypeptidase regulatory-like domain;


:

Pssm-ID: 433354 [Multi-domain]  Cd Length: 81  Bit Score: 48.82  E-value: 3.25e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 940641997    40 AGYTVTVKNPATGLERTLNISEDGSFRFASLPSGSYQIQILKNG-AVVAEDSVRVSLGANAKASFDL 105
Cdd:pfam13620   15 PGATVTVTNTDTGTVRTTTTDADGRYRFPGLPPGTYTVTVSAPGfKTATRTGVTVTAGQTTTLDVTL 81
 
Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
90-640 4.76e-32

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 133.06  E-value: 4.76e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   90 SVRVSLGANAKASFDLAQVSDSGPEVIqVLGARISSIDLTTADSGLVITDAEIDRMPInRDLTSVALLAPG---AVKGDS 166
Cdd:COG4771     5 SLLLLLALAAQAADALAEDATELEEVV-VTATRTEQSLSDAPASVSVITAEEIEKLGA-TDLADALRLLPGvsvTRSGGR 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  167 AFGNTASFGGSSVAENACYINGLEVTNTRQGLGCG--EVPFEFYDQFQVKTGGYSAKFG-RATGGTINTTTKSGTNEWEF 243
Cdd:COG4771    83 GGSSGISIRGLGGDRVLVLIDGVPVNNPALGGGGDlsYIPPDDIERIEVIRGPASALYGsDAIGGVINIITKKPTDELEG 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  244 aavvqfqpdslqeEGSISRGNNGAGQIfrdesldtdsktDVTISAGGPliEDTLFFYGLINPRDTESTYTWGGDEFSPND 323
Cdd:COG4771   163 -------------SVSLGYGSNGNGTY------------SGSLSLGGP--GDKLSFLLSGSYRDRDGYLDYRNGGFVGNS 215
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  324 QYRNESAsggdnlfwGGKLDWDINENHRLSYFAYSNRRDIERSVYEYNNG-TVGDRIDGAILKRGGEAQSLSYTGVLTED 402
Cdd:COG4771   216 GYERYNL--------NAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTeISSDNAGDRDTTTDRGNYSLRYNGDLGDN 287
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  403 LVVTAmagnikteyetqsenlvcpSITDSRGTANPITGCGAGGSFGANNDENTQYRLDVEYVWND-HEITFGIDYQErks 481
Cdd:COG4771   288 LDLSL-------------------YYSRTDRDSTNGSLGGSTGSFSDSDDTTYGLELDLTYPLGGnHTLTLGAEYRY--- 345
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  482 enisspigghsydyrtladngswqadngaltnntgaalDYVEDRIFDGGGSFESELTAYYIEDQWQVTEDFSVKVGLRID 561
Cdd:COG4771   346 --------------------------------------DDLDSSSFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLRYD 387
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 940641997  562 EFDSWGTTGKLLTSfetdiaPRLGFTWDPtgTGDTKVYGTYGRYylpvanntiFRAASgVSDITTAYTYTGVDSQTGAP 640
Cdd:COG4771   388 YYSTFGASNYTAFS------PRLGLRYDL--SDNLTLRASYGRG---------FRAPS-LAELYGSGTGTPGRYVLGNP 448
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
136-604 2.01e-15

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 80.96  E-value: 2.01e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  136 VITDAEIDRMPINrDLTSVALLAPG--AVKGDSAFGNTASFGGSSVAENACYINGLEVTNTRQGLGCG--EVPFEFYDQF 211
Cdd:cd01347     4 VITAEDIEKQPAT-SLADLLRRIPGvsVTRGGGGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRGVDlnTIPPELIERV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  212 QVKTGGYSAKFGR-ATGGTINTTTKSGTNEWEFAAVVQFqpdslqeeGSISRGNNGagqifrdesldtdsktDVTISAGG 290
Cdd:cd01347    83 EVLKGPSSALYGSgAIGGVVNIITKRPTDEFGGSVTAGY--------GSDNSGSSG----------------GGGFDVSG 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  291 PLIEDTLF---FYGLINPRDTestYTWGGDEFSPNDQYRNesasggdnlFWGGKLDWDINENHRLSYFAYSNRRDIERSV 367
Cdd:cd01347   139 ALADDGAFgarLYGAYRDGDG---TIDGDGQADDSDEERY---------NVAGKLDWRPDDDTRLTLDAGYQDQDADGPG 206
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  368 YEYNNGTVGDRIDGAILKRGGEAQSLSYTGVLTEDLVVTAMAGnikteyetqsenlvcpsitdsrgtanpitgcgaggsf 447
Cdd:cd01347   207 GTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLEHD------------------------------------- 249
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  448 gaNNDENTQYRLDVEYVWNDHEITFGIDYQERKSENISSPIGGHSYDYRTLAD------NGSWQADNGALTNNTGaaLDY 521
Cdd:cd01347   250 --LNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLgfdaglNAPFGTGPVAHTLTLG--VEY 325
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  522 VEDRifdgggsFESELTAYYIEDQWQVTEDFSVKVGLRID----EFDSWGTTGKLLTSFETDIAPRLGFTWDPTGTgdTK 597
Cdd:cd01347   326 RREE-------LDEKQTALYAQDTIELTDDLTLTLGLRYDhydqDSKDTIAGGTTAKKSYSHWSPSLGLVYKLTDG--LS 396

                  ....*..
gi 940641997  598 VYGTYGR 604
Cdd:cd01347   397 LYASYSQ 403
CarboxypepD_reg pfam13620
Carboxypeptidase regulatory-like domain;
40-105 3.25e-07

Carboxypeptidase regulatory-like domain;


Pssm-ID: 433354 [Multi-domain]  Cd Length: 81  Bit Score: 48.82  E-value: 3.25e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 940641997    40 AGYTVTVKNPATGLERTLNISEDGSFRFASLPSGSYQIQILKNG-AVVAEDSVRVSLGANAKASFDL 105
Cdd:pfam13620   15 PGATVTVTNTDTGTVRTTTTDADGRYRFPGLPPGTYTVTVSAPGfKTATRTGVTVTAGQTTTLDVTL 81
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
442-638 3.23e-04

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 44.38  E-value: 3.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   442 GAGGSFGANNDENTQYRLDVEYVWNDHEITFGIDYQERKSENISSPIGGHSYDYRTLADNGSWQADNGALTNNTGAALDY 521
Cdd:pfam00593   72 GDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDD 151
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   522 VEDRIFDGGGS-------FESELTAYYIEDQWQVTEDFSVKVGLRIDEFD----SWGTTGKLLTSFETDIAPRLGFTWDP 590
Cdd:pfam00593  152 DAYDPYDPANPssssysdTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYStdgdDGNGGGDNFSRSYSAFSPRLGLVYKP 231
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 940641997   591 tgTGDTKVYGTYGRYYLPVANNTIFRAASGVSDITTAYTYTGVDSQTG 638
Cdd:pfam00593  232 --TDNLSLYASYSRGFRAPSLGELYGSGSGGGGGAVAGGNPDLKPETS 277
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
130-644 4.38e-04

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 44.33  E-value: 4.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   130 TADSGLVITDAEIDRMPINRDLTSVALLAPGAVKGDSAFGNTASFG----GSSVAENACYINGLEVTNTrqgLGCGEVPF 205
Cdd:TIGR01783    2 IPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQFGNITirgfGLEVDIDNVYLDGVPLLSR---GNLAIVDP 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   206 EFYDQFQVKTGGYSAKFGR-ATGGTINTTTKSGTNewEFAAVVQFqpdslqeeGSISRGNNGAgqifrdesldtdsktdv 284
Cdd:TIGR01783   79 AMVERVEVLRGPASLLYGGsAPGGVINIVTKRPQD--EPKGSVTF--------GAGTRSGYRT----------------- 131
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   285 TISAGGPLIEDTLfFYGLINPRdtestytwggdeFSPNDQYRNesASGGDNLFWGGKLDWDINE--NHRLSYFAYSNRRD 362
Cdd:TIGR01783  132 AFDLGGPLGADGT-FRGRLNGA------------RQDGDSFYD--GAGEETRLGATATDWQLDDrtLLRLGAYYQKERDR 196
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   363 IERSVYEYNNGTVG-----DRIDGAILKRG---GEAQSLSYTGVLTEDLVVTAMAGNIKTEYETQSENLVCPSITDSRGt 434
Cdd:TIGR01783  197 GGYGGLPASGGTSGrdlssDRYLGTSSNRNyddREYLSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSDGG- 275
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   435 anpitgcGAGGSFGANNDENTQYRLDVEYVWN------DHEITFGIDYQERKSENISSPiGGHSYDYRtladngSWQADN 508
Cdd:TIGR01783  276 -------LFGRSLTVVNVKQDRVQIDAGLDGEfetgpiEHDLLLGVSYGQRTTNRFNNT-GYPSDNIY------SLTATS 341
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   509 GALTNNTGAALDYVEDRIFDGGGSFesELTAYYIEDQWQVTedfsvkVGLRIDEFDSWGTTGKLLTSFETD---IAPRLG 585
Cdd:TIGR01783  342 SARTDIGDSPKDRALSSTTKALNGV--ALQRILLADKWTLT------LGGRYDSVDVKSNNGVAGSTGKRDdsqFTPSLG 413
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 940641997   586 FTWDPtgTGDTKVYGTYGRYYLPVANNTIF--RAASGVSDITTAYTYTGVDSQTGAPTGLT 644
Cdd:TIGR01783  414 VAYKP--TDDWSLYASYAESFKPGGYYPKGagNSGDILEPEKGKNYELGVRYDLGDSLLAT 472
 
Name Accession Description Interval E-value
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
90-640 4.76e-32

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 133.06  E-value: 4.76e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   90 SVRVSLGANAKASFDLAQVSDSGPEVIqVLGARISSIDLTTADSGLVITDAEIDRMPInRDLTSVALLAPG---AVKGDS 166
Cdd:COG4771     5 SLLLLLALAAQAADALAEDATELEEVV-VTATRTEQSLSDAPASVSVITAEEIEKLGA-TDLADALRLLPGvsvTRSGGR 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  167 AFGNTASFGGSSVAENACYINGLEVTNTRQGLGCG--EVPFEFYDQFQVKTGGYSAKFG-RATGGTINTTTKSGTNEWEF 243
Cdd:COG4771    83 GGSSGISIRGLGGDRVLVLIDGVPVNNPALGGGGDlsYIPPDDIERIEVIRGPASALYGsDAIGGVINIITKKPTDELEG 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  244 aavvqfqpdslqeEGSISRGNNGAGQIfrdesldtdsktDVTISAGGPliEDTLFFYGLINPRDTESTYTWGGDEFSPND 323
Cdd:COG4771   163 -------------SVSLGYGSNGNGTY------------SGSLSLGGP--GDKLSFLLSGSYRDRDGYLDYRNGGFVGNS 215
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  324 QYRNESAsggdnlfwGGKLDWDINENHRLSYFAYSNRRDIERSVYEYNNG-TVGDRIDGAILKRGGEAQSLSYTGVLTED 402
Cdd:COG4771   216 GYERYNL--------NAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTeISSDNAGDRDTTTDRGNYSLRYNGDLGDN 287
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  403 LVVTAmagnikteyetqsenlvcpSITDSRGTANPITGCGAGGSFGANNDENTQYRLDVEYVWND-HEITFGIDYQErks 481
Cdd:COG4771   288 LDLSL-------------------YYSRTDRDSTNGSLGGSTGSFSDSDDTTYGLELDLTYPLGGnHTLTLGAEYRY--- 345
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  482 enisspigghsydyrtladngswqadngaltnntgaalDYVEDRIFDGGGSFESELTAYYIEDQWQVTEDFSVKVGLRID 561
Cdd:COG4771   346 --------------------------------------DDLDSSSFLGGADASRDTYGLFAQDEWKLTDKLTLTAGLRYD 387
                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 940641997  562 EFDSWGTTGKLLTSfetdiaPRLGFTWDPtgTGDTKVYGTYGRYylpvanntiFRAASgVSDITTAYTYTGVDSQTGAP 640
Cdd:COG4771   388 YYSTFGASNYTAFS------PRLGLRYDL--SDNLTLRASYGRG---------FRAPS-LAELYGSGTGTPGRYVLGNP 448
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
114-606 5.81e-17

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 85.65  E-value: 5.81e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  114 EVIQVLGARISSIDLTTADSGLVITDAEIDRMPINrDLTSVALLAPG-AVKGDSAFGNTASFGGSSVAENAC--YINGLE 190
Cdd:COG1629     2 EEVVVTATRTDESLQDVPGSVSVISREQLEDQPAT-DLGDLLRRVPGvSVTSAGGGAGQISIRGFGGGGNRVlvLVDGVP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  191 VTNTRQGL-GCGEVPFEFYDQFQVKTGGYSAKFGR-ATGGTINTTTKSGTNEWEFaavvqfqpdslqeEGSISRGNNGag 268
Cdd:COG1629    81 LNDPSGGDgGLSYIDPEDIERVEVLRGPSSALYGSgALGGVINIVTKKPKDGKGG-------------EVSASYGSYG-- 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  269 qifrdesldtdsKTDVTISAGGPliEDTLFFYGLINPRDTESTYTWggdefspndqyrnesaSGGDNLFWGGKLDWDINE 348
Cdd:COG1629   146 ------------TYRASLSLSGG--NGKLAYRLSASYRDSDGYRDN----------------SDSDRYNLRAKLGYQLGD 195
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  349 NHRLSYFAYSNRRDIERSVY----------EYNNGTVGDRIDGAILKRGGEAQSLSYTGvLTEDLVVTAMAGnikteYET 418
Cdd:COG1629   196 DTRLTLSASYSDSDQDSPGYltlaalrprgAMDDGTNPYSNDTDDNTRDRYSLSLEYEH-LGDGLKLSASAY-----YRY 269
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  419 QSENlvcpsiTDSRGTANPITgcgaGGSFGANNDENTQYRLDVEYVWN-----DHEITFGIDYQERKSENISSPIGGHSY 493
Cdd:COG1629   270 DDTD------LDSDFTPTPAD----GGTLEQTDFDNRTYGLELRLTYDlgfggKHTLLVGLDYQRQDLDGSGYPLDLGSG 339
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  494 DYRTLADNGSWQADNgaltnntgaaldyvedrifdgggsfesELTAYYIEDQWQVTEDFSVKVGLRID------EFDSWG 567
Cdd:COG1629   340 SLPTLTSGADDDGTT---------------------------TSLALYAQDTYKLTDKLTLTAGLRYDyvsydvDDTVTG 392
                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 940641997  568 TTGKLLTSFETDIAPRLGFTWDPtgTGDTKVYGTYGRYY 606
Cdd:COG1629   393 TDSASGSRSYSAFSPSLGLTYQL--SPNLSLYASYSRGF 429
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
136-604 2.01e-15

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 80.96  E-value: 2.01e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  136 VITDAEIDRMPINrDLTSVALLAPG--AVKGDSAFGNTASFGGSSVAENACYINGLEVTNTRQGLGCG--EVPFEFYDQF 211
Cdd:cd01347     4 VITAEDIEKQPAT-SLADLLRRIPGvsVTRGGGGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRGVDlnTIPPELIERV 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  212 QVKTGGYSAKFGR-ATGGTINTTTKSGTNEWEFAAVVQFqpdslqeeGSISRGNNGagqifrdesldtdsktDVTISAGG 290
Cdd:cd01347    83 EVLKGPSSALYGSgAIGGVVNIITKRPTDEFGGSVTAGY--------GSDNSGSSG----------------GGGFDVSG 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  291 PLIEDTLF---FYGLINPRDTestYTWGGDEFSPNDQYRNesasggdnlFWGGKLDWDINENHRLSYFAYSNRRDIERSV 367
Cdd:cd01347   139 ALADDGAFgarLYGAYRDGDG---TIDGDGQADDSDEERY---------NVAGKLDWRPDDDTRLTLDAGYQDQDADGPG 206
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  368 YEYNNGTVGDRIDGAILKRGGEAQSLSYTGVLTEDLVVTAMAGnikteyetqsenlvcpsitdsrgtanpitgcgaggsf 447
Cdd:cd01347   207 GTLPANGTGSSLGGGPSSNTNGDRDWDYRDRYRKRASLGLEHD------------------------------------- 249
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  448 gaNNDENTQYRLDVEYVWNDHEITFGIDYQERKSENISSPIGGHSYDYRTLAD------NGSWQADNGALTNNTGaaLDY 521
Cdd:cd01347   250 --LNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSERDTTQLgfdaglNAPFGTGPVAHTLTLG--VEY 325
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  522 VEDRifdgggsFESELTAYYIEDQWQVTEDFSVKVGLRID----EFDSWGTTGKLLTSFETDIAPRLGFTWDPTGTgdTK 597
Cdd:cd01347   326 RREE-------LDEKQTALYAQDTIELTDDLTLTLGLRYDhydqDSKDTIAGGTTAKKSYSHWSPSLGLVYKLTDG--LS 396

                  ....*..
gi 940641997  598 VYGTYGR 604
Cdd:cd01347   397 LYASYSQ 403
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
136-611 4.31e-10

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 63.76  E-value: 4.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  136 VITDAEIDRMPInRDLTSVALLAPGAVKGDSAFGNTASFG--GSSVAENacYINGLEVTNTRQGLgcgeVPFEFYDQFQV 213
Cdd:COG4773    71 VVTRQLIEDQGA-TTLDDALRNVPGVTVSSYDGGGRDSFSirGFSIDNY--LRDGLPLGGFGGGQ----PDTANLERVEV 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  214 KTGGYSAKFGRAT-GGTINTTTKSGTNEWefaavvqfqpdslQEEGSISRGNNGAGQifrdesldtdsktdVTISAGGPL 292
Cdd:COG4773   144 LKGPAGLLYGAGSpGGLVNLVTKRPTAEP-------------QGEVSLSAGSWDTYR--------------ATADVGGPL 196
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  293 IEDTLFFYGLInprdtesTYTWGGDEFSPNDQYRNESASGGdnlfwggkLDWDINENHRLSyFAYSNRRDIERSVYEY-- 370
Cdd:COG4773   197 NEDGTLRYRLN-------AAYEDGDSFRDGVDNRRTLIAPS--------LDWDLTDDTTLT-LGAEYQDDDSTGDRGFlp 260
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  371 NNGTVGD-----RIDGAILKRGGEAQSLSYTGV--LTEDLVVTAMAGNIKTEYETQSenlvcpsiTDSRGTANPITGcGA 443
Cdd:COG4773   261 LDGTLLDlprstNLGEPWDYYDTETTTLFAELEhrFNDDWSLRANARYSDSDRDGRS--------AYAYGAPDAATG-TL 331
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  444 GGSFGANNDENTQYRLDVEYVWN------DHEITFGIDYQERKSENISSPIGG---HSYDYRTLADNGSWQADNGALTNN 514
Cdd:COG4773   332 TRYASARDGDSRSDSLDANLNGKfetgglEHTLLVGADYSRYDSDSDSATAGTiniYNPVYGNLPEPDFDASDTDTTTRQ 411
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  515 TGAaldyvedrifdgggsfeseltayYIEDQWQVTEDFSVKVGLRIDEFDSWGTTGKLLTSFETD---IAPRLGFTWDPt 591
Cdd:COG4773   412 TGL-----------------------YAQDQISLTDRLSLLLGGRYDWYETDSTNRLGGSTTSYDdsaFTPRAGLVYDL- 467
                         490       500
                  ....*....|....*....|
gi 940641997  592 gTGDTKVYGTYGRYYLPVAN 611
Cdd:COG4773   468 -TPGLSLYASYSESFEPQSG 486
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
136-630 3.21e-09

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 60.66  E-value: 3.21e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  136 VITDAEIDRMPInRDLTSVALLAPGAVKGDSAFGNTASF---GGSSVAENacYINGLEVTNTRQglgcgeVPFEFYDQFQ 212
Cdd:COG4774    15 VVTRELIEDQGA-TSLADALRNVPGVTFGAGEGGNGDSFsirGFSASGDI--YVDGLRDPGQYR------RDTFNLERVE 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  213 VKTGGYSAKFGR-ATGGTINTTTKSGTNEWEFAAVVqfqpdslqeegsisrgnngagqifrdeSLDTDSKTDVTISAGGP 291
Cdd:COG4774    86 VLKGPASVLYGRgSPGGVINLVTKRPTDEPFTEVTL---------------------------TYGSDGQRRATLDVNGP 138
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  292 LIEDTLF-FYGLInpRDTEStytwggdefspndqYRNESASggDNLFWGGKLDWDINENHR--LSYFAYSNRRDIERSVY 368
Cdd:COG4774   139 LGDDLAYrLNGMY--RDSDS--------------YRDGVDN--DRWGIAPSLTWRLGDRTRltLDYEYQDDDRTPDYGVP 200
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  369 EYNNGTV------------GDRIDgailkrgGEAQSLSYTG--VLTEDLVVTAMAGNIKTEYETQSenlVCPSITDSRGT 434
Cdd:COG4774   201 AVANGRPvdvdrstfygqpDDYSD-------SETDSATLRLehDFNDNWTLRNALRYSDYDRDYRN---TYPTGGNATGT 270
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  435 ANpitgcgAGGSFGANNDENTQYRLDVEYVWN----DHEITFGIDY--QERKSENISSPIGGHSYDYRTLADNGSWQADN 508
Cdd:COG4774   271 VT------RSAYRRDQDNDTLSNQTDLTGKFDtggvKHTLLAGVEYsrEDSDNARYSGGGTAPTVNLYNPVYGAPVTGPT 344
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  509 GALTNNTGaaldyvedrifdgggsfESELTAYYIEDQWQVTEDFSVKVGLRIDEF--DSWGTTGKLLTSFETDIA--PRL 584
Cdd:COG4774   345 LGGADNDS-----------------RTDTTGLYLQDTISLTDRWSLLAGLRYDRFdtDYTDRTTGATTSSYDDSAfsPRA 407
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 940641997  585 GFTWDPtgTGDTKVYGTYGRYYLPVANNTIFRAASGVSDITTAYTY 630
Cdd:COG4774   408 GLVYKP--TPNLSLYASYSTSFNPGGGAPSLSNAGQALDPEKSRQY 451
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
116-423 1.39e-07

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 54.11  E-value: 1.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  116 IQVLGARISSIDLTTADSGLVITDAEIDRMPiNRDLTSVALLAPG-AVKGDSAFGNTASFG--GSSVAENACYINGLEVT 192
Cdd:COG4206     1 VVVTATRLEQSKSDLTGSVTVIDAEELERSG-ATSLADALRRVPGvQVSSSGGPGSAASISirGLGSNQTLVLIDGVPLN 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  193 NTRQG-LGCGEVPFEFYDQFQVKTGGYSAKFG-RATGGTINTTTKSGTNEWEFAAvvqfqpdslqeegSISRGNNGAGQI 270
Cdd:COG4206    80 DPSLGgVDLSLIPPDDIERIEVLKGAASALYGsDAIGGVINITTKKGKKGFKGSV-------------SASYGSFGTRRL 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  271 FRDESLDTDsKTDVTISAGGpliedtlffyglinprdtestytWGGDEFSPNDQYRNEsASGGDNLFWGGKLDWDINENH 350
Cdd:COG4206   147 SASLSGGAG-KFSYSLSASY-----------------------RRSDGYRYNDPDLRN-NDGYENTSLNARLGYKLGDNG 201
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 940641997  351 RLSYFAYSNRRDieRSVYEYNNGTVGDRIDGAILKRGGEAQSLSYTGVLTEDLVVTAMAGNIKTEYETQSENL 423
Cdd:COG4206   202 SLSLSGGYSDSE--RGYPGAVGSDRNLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARA 272
CarboxypepD_reg pfam13620
Carboxypeptidase regulatory-like domain;
40-105 3.25e-07

Carboxypeptidase regulatory-like domain;


Pssm-ID: 433354 [Multi-domain]  Cd Length: 81  Bit Score: 48.82  E-value: 3.25e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 940641997    40 AGYTVTVKNPATGLERTLNISEDGSFRFASLPSGSYQIQILKNG-AVVAEDSVRVSLGANAKASFDL 105
Cdd:pfam13620   15 PGATVTVTNTDTGTVRTTTTDADGRYRFPGLPPGTYTVTVSAPGfKTATRTGVTVTAGQTTTLDVTL 81
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
216-630 1.93e-06

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 51.85  E-value: 1.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  216 GGYSAKFG-RATGGTINTTTKSGTNEWEFAAVVQFqpdslqeegsisrGNNGagqifrdesldtdsKTDVTISAGGPLie 294
Cdd:COG4772   134 GAAALRYGpQTVGGAINFVTRTIPTAFGGELRVTG-------------GSFG--------------YRRTHASVGGTV-- 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  295 DTLFFYGLINPRDTestytwggdefspnDQYRNESASGGDNLFwgGKLDWDINENHRLS-YFAYSN-------------- 359
Cdd:COG4772   185 GNFGYLVEYSRKRG--------------DGFRDNSGFDINDFN--AKLGYRLSDRQELTlKFQYYDedantpggltdaqf 248
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  360 RRDIERSVYEYNNGTvGDRIDGailkrggeaqSLSYTGVLTEDLVVTAMAgnikteYETQSENlvcPSITDSRGTANPIT 439
Cdd:COG4772   249 DADPRQSYRPADQFD-TRRTQL----------SLRYEHQLSDNTTLTTTA------YYNDFSR---NWYIRQNTADPNTP 308
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  440 GCGAGGSFGANNDENTQYRLDVEYVWN--DHEITFGIDYQerksenisspiggHSYDYRTLADNGSWQADNGALTNNtga 517
Cdd:COG4772   309 GLGLRGNPRGYRSYGIEPRLTHRFELGgvPHTLEVGLRYH-------------REEEDRKQYVNTYGQGRSGAGLRR--- 372
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997  518 aldyveDRIFdgggsfESELTAYYIEDQWQVTEDFSVKVGLRIDEFDS-------WGTTGKLLTSFETD-IAPRLGFTWD 589
Cdd:COG4772   373 ------DRRF------SADALAAYAQNRFELTGRLTLTPGLRYEHIRRdrtdrysTRTGGDDSGSNSYSeFLPGLGLLYQ 440
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 940641997  590 PtgTGDTKVYGTYGRYYLPVANNTIFRAASGVSDIT--TAYTY 630
Cdd:COG4772   441 L--TDNLQLYANVSRGFEPPTFGDLAYGNGGNPDLKpeKSWNY 481
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
442-638 3.23e-04

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 44.38  E-value: 3.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   442 GAGGSFGANNDENTQYRLDVEYVWNDHEITFGIDYQERKSENISSPIGGHSYDYRTLADNGSWQADNGALTNNTGAALDY 521
Cdd:pfam00593   72 GDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDD 151
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   522 VEDRIFDGGGS-------FESELTAYYIEDQWQVTEDFSVKVGLRIDEFD----SWGTTGKLLTSFETDIAPRLGFTWDP 590
Cdd:pfam00593  152 DAYDPYDPANPssssysdTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYStdgdDGNGGGDNFSRSYSAFSPRLGLVYKP 231
                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 940641997   591 tgTGDTKVYGTYGRYYLPVANNTIFRAASGVSDITTAYTYTGVDSQTG 638
Cdd:pfam00593  232 --TDNLSLYASYSRGFRAPSLGELYGSGSGGGGGAVAGGNPDLKPETS 277
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
130-644 4.38e-04

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 44.33  E-value: 4.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   130 TADSGLVITDAEIDRMPINRDLTSVALLAPGAVKGDSAFGNTASFG----GSSVAENACYINGLEVTNTrqgLGCGEVPF 205
Cdd:TIGR01783    2 IPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQFGNITirgfGLEVDIDNVYLDGVPLLSR---GNLAIVDP 78
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   206 EFYDQFQVKTGGYSAKFGR-ATGGTINTTTKSGTNewEFAAVVQFqpdslqeeGSISRGNNGAgqifrdesldtdsktdv 284
Cdd:TIGR01783   79 AMVERVEVLRGPASLLYGGsAPGGVINIVTKRPQD--EPKGSVTF--------GAGTRSGYRT----------------- 131
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   285 TISAGGPLIEDTLfFYGLINPRdtestytwggdeFSPNDQYRNesASGGDNLFWGGKLDWDINE--NHRLSYFAYSNRRD 362
Cdd:TIGR01783  132 AFDLGGPLGADGT-FRGRLNGA------------RQDGDSFYD--GAGEETRLGATATDWQLDDrtLLRLGAYYQKERDR 196
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   363 IERSVYEYNNGTVG-----DRIDGAILKRG---GEAQSLSYTGVLTEDLVVTAMAGNIKTEYETQSENLVCPSITDSRGt 434
Cdd:TIGR01783  197 GGYGGLPASGGTSGrdlssDRYLGTSSNRNyddREYLSYGLSLEYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSDGG- 275
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   435 anpitgcGAGGSFGANNDENTQYRLDVEYVWN------DHEITFGIDYQERKSENISSPiGGHSYDYRtladngSWQADN 508
Cdd:TIGR01783  276 -------LFGRSLTVVNVKQDRVQIDAGLDGEfetgpiEHDLLLGVSYGQRTTNRFNNT-GYPSDNIY------SLTATS 341
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940641997   509 GALTNNTGAALDYVEDRIFDGGGSFesELTAYYIEDQWQVTedfsvkVGLRIDEFDSWGTTGKLLTSFETD---IAPRLG 585
Cdd:TIGR01783  342 SARTDIGDSPKDRALSSTTKALNGV--ALQRILLADKWTLT------LGGRYDSVDVKSNNGVAGSTGKRDdsqFTPSLG 413
                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 940641997   586 FTWDPtgTGDTKVYGTYGRYYLPVANNTIF--RAASGVSDITTAYTYTGVDSQTGAPTGLT 644
Cdd:TIGR01783  414 VAYKP--TDDWSLYASYAESFKPGGYYPKGagNSGDILEPEKGKNYELGVRYDLGDSLLAT 472
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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