|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1037 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1496.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 1 MIESIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQ 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 81 TVRGYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQLGPDATGVGWVYIYALTDKSGNHDLSQLRSIQ 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGKYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 161 DWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSV 240
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 241 SDIEKIPLGiNEQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVVMRFGENAQQTINGVKEKLESLKSSLPEGVE 320
Cdd:COG3696 241 EDIENIVVK-TRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 321 VVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAI 400
Cdd:COG3696 320 IVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 401 GAMTDGAIVMIENMHKHMEKTP--LTDENRWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLAYTKTYA 478
Cdd:COG3696 400 GIIVDGAVVMVENILRRLEENRaaGTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 479 MAASAGLAITLVPVLMGYFIRGKVvSEKKNPLNRLLIAIYMPVLKQVMKFPKLTIVAAVLVTIVGFWPVDKIGSEFIPPL 558
Cdd:COG3696 480 LLGALLLSLTLVPVLASLLLRGKV-PEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPEL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 559 DEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAETATDPAPLTMIETFIQLKPREEWREGVTTESL 638
Cdd:COG3696 559 DEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGRTKEEL 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 639 KAEFD-KLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQDIGQQIEQLLPEVTGTASVYSERVAGGRYI 717
Cdd:COG3696 639 IAEMReALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQL 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 718 KVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQLARLPVVTPSGQRIALGDVADI 797
Cdd:COG3696 719 DIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADI 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 798 RVENGPPGIKSENARINGWTFIDIDSVDVGTYVENAKEHLANNLTLPAGYSITWAGQYEYMERAKEKLTYVLPLTLAIIV 877
Cdd:COG3696 799 EVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIF 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 878 ILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQALAelkekavERAE 957
Cdd:COG3696 879 LLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRA-------EGLD 951
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 958 LisddayQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVLLTLIVLPAIYSIIKKPE 1037
Cdd:COG3696 952 L------REAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRR 1025
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1033 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1165.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 1 MIESIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQ 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 81 TVRGYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQLGPDATGVGWVYIYALTDKSGN-------HDL 153
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGArkkdggaYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 154 SQLRSIQDWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTA 233
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 234 TGYIQSVSDIEKIPLGiNEQGTPLRIGDVANVNLGPQMRRGIAELNgEGEVVGGVVVMRFGENAQQTINGVKEKLESLKS 313
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATEN-GKEVVLGTVFMLIGENSRTVAQAVGDKLETINK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 314 SLPEGVEVVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSL 393
Cdd:TIGR00914 319 TLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 394 GgiAIAIGAMTDGAIVMIENMHKHMEK------TPLTDENRWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRM 467
Cdd:TIGR00914 399 G--ALDFGLIVDGAVVIVENAHRRLAEaqhhhgRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKM 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 468 FSPLAYTKTYAMAASAGLAITLVPVLMGYFIRGKvVSEKKNPLNRLLIAIYMPVLKQVMKFPKLTIVAAVLVTIVGFWPV 547
Cdd:TIGR00914 477 FHPMAFTVVLALAGAMILSLTFVPAAVALFIRGK-VAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIA 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 548 DKIGSEFIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAETATDPAPLTMIETFIQLKPRE 627
Cdd:TIGR00914 556 SRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPES 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 628 EWREGVTT--ESLKAEFDKLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQDIGQQIEQLLPEVTGTAS 705
Cdd:TIGR00914 636 QWPEGKKTkeDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAAD 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 706 VYSERVAGGRYIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQLARLPVVTPS 785
Cdd:TIGR00914 716 VKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPL 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 786 G-----QRIALGDVADIRVENGPPGIKSENARINGWTFIDIDSVDVGTYVENAKEHLANNLTLPAGYSITWAGQYEYMER 860
Cdd:TIGR00914 796 SedarkQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQS 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 861 AKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVY 940
Cdd:TIGR00914 876 ATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISF 955
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 941 LNQALAELKekaveraelisddAYQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVL 1020
Cdd:TIGR00914 956 IRKLLEEGP-------------SLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATL 1022
|
1050
....*....|...
gi 940688358 1021 LTLIVLPAIYSII 1033
Cdd:TIGR00914 1023 LTLFVLPALYRLV 1035
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1034 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 706.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 5 IIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRG 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 85 YSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ-LGPDATGVGWVYIYALTDKSGNHDLSQLRSIQDWF 163
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPgISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 164 LKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSVSDI 243
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 244 EKIPLGiNEQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGVEVVP 323
Cdd:pfam00873 241 EKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQ-KLPGANAIETADAVRAKLAELKPTFPQGVEIVV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 324 VYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAM 403
Cdd:pfam00873 319 VYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLV 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 404 TDGAIVMIENMHKHMEKTPLTdeNRwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLAYTKTYAMAASA 483
Cdd:pfam00873 399 VDDAIVVVENIERVLEENGLK--PL-EAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 484 GLAITLVPVLMGYFIRGKVVSEKK------NPLNRLLIAIYMPVLKQVMKFPKLTIVAAVLVTIVGFWPVDKIGSEFIPP 557
Cdd:pfam00873 476 LVALTLTPALCATLLKPRREPKHGgffrwfNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPE 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 558 LDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAEtATDPAPLTMIETFIQLKPREEWREGVTT-- 635
Cdd:pfam00873 556 EDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAF-SGDNNGPNSGDAFISLKPWKERPGPEKSvq 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 636 ESLKAEFDKLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQDIGQQIEQLLPEVTGTASVYSERVAGGR 715
Cdd:pfam00873 635 ALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQP 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 716 YIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQLARLPVVTPSGQRIALGDVA 795
Cdd:pfam00873 715 QLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFA 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 796 DIRVENGPPGIKsenaRINGWTFIDIDSV----DVGTYVENAKEHLANNLTLPAGYSITWAGQYEYMERAKEKLTYVLPL 871
Cdd:pfam00873 795 KIEWGYGPPSIN----RYNGFRSIVISGNvaagDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIAL 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 872 TLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQALAELKEK 951
Cdd:pfam00873 871 ALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKS 950
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 952 AVEraelisddayqdALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVLLTLIVLPAIYS 1031
Cdd:pfam00873 951 LEE------------AILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYV 1018
|
...
gi 940688358 1032 IIK 1034
Cdd:pfam00873 1019 LFH 1021
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
17-1035 |
4.35e-126 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 409.41 E-value: 4.35e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 17 LLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYSFFGDSYVYII 96
Cdd:NF033617 12 LLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 97 FDDDTDLYWARSRVLEYLSQVASSLPDSAKP-----QLGPDATGVgwVYIyALTdkSGNHDLSQLRSIQDWFLKYELQTV 171
Cdd:NF033617 92 FRLGTDLDVALSEVQAAINAAQSLLPSEAPDppvyrKANSADTPI--MYI-GLT--SEEMPRGQLTDYAERVLAPKLSQI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 172 PGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSVSDIEKIPLGIN 251
Cdd:NF033617 167 NGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 252 EQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVVMRfGENAQQTINGVKEKLESLKSSLPEGVEVVPVYDRSKLI 331
Cdd:NF033617 247 DNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQP-GANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFI 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 332 DRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGAIVMI 411
Cdd:NF033617 326 RASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVV 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 412 ENMHKHME--KTPLtdenrwQIVAKAASEVG-PALFFSLLIITVsFLPVFILEAQEGRMFSPLAYTKTYAMAASAGLAIT 488
Cdd:NF033617 406 ENIHRHIEegESPL------EAALKGAREIGfTVIAMTLTLVAV-YLPILFMGGLTGRLFREFAVTLAGAVIISGIVALT 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 489 LVPVLMGYFIRGkvvSEKKNPLNRL-------LIAIYMPVLKQVMKFPKLTIVAAVLVTIVGFWPVDKIGSEFIPPLDEG 561
Cdd:NF033617 479 LTPMMCSRLLKA---NEKPGRFARAvdrffdgLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRG 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 562 DLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAETATDPAPLtmieTFIQLKPREEwREGVTTESLKAE 641
Cdd:NF033617 556 VIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNPGDNTGF----GIINLKPWDE-RDVSAQEIIDRL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 642 FDKLVKFPGLtNAWVMPIKTrIDMLATGIKTPVGIKVAGPELDVIQDIGQQIEQLLPEVTGTASVYSERVAGGRYIKVDI 721
Cdd:NF033617 631 RPKLAKVPGM-DLFLFPLQD-LPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDI 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 722 SRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQLARLPVVTPSGQRIALGDVADIRVEN 801
Cdd:NF033617 709 DRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERA 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 802 GPPGIkSENARINGWT--FIDIDSVDVGTYVEnAKEHLANNLtLPAGYSITWAGQYEYMERAKEKLTYVLPLTLAIIVIL 879
Cdd:NF033617 789 APLSL-NHFNQFNSATlsFNLAPGVSLGEAIE-ALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLV 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 880 LYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQAlaeLKEKAVERaeli 959
Cdd:NF033617 866 LAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANEL---QRHQGLSR---- 938
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 940688358 960 sddayQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVLLTLIVLPAIYSIIKK 1035
Cdd:NF033617 939 -----REAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
17-1037 |
5.18e-69 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 250.52 E-value: 5.18e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 17 LLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYSF--FGDSYVY 94
Cdd:PRK09579 15 SVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRqnFSIISIY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 95 IIFDDDTDLYWarSRVLEYLSQVASSLP-DSAKPQLGPDAT-GVGWVYIYALTDKSGNHDLSQL--RSIQDwflkyELQT 170
Cdd:PRK09579 95 ARIGADSDRLF--TELLAKANEVKNQLPqDAEDPVLSKEAAdASALMYISFYSEEMSNPQITDYlsRVIQP-----KLAT 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 171 VPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEmaeAEYMVT---ATGYIQSVSDIEKIP 247
Cdd:PRK09579 168 LPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVK---GEYVVTsinASTELKSAEAFAAIP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 248 LGINEQgTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVVMRfGENAQQTINGVKEKLESLKSSLPEGVEVVPVYDR 327
Cdd:PRK09579 245 VKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATP-SANPLDVIKEVRAIMPELESQLPPNLKVSIAYDA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 328 SKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGA 407
Cdd:PRK09579 323 TLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDA 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 408 IVMIENMHKHME--KTPLtdenrwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLAYTKTYAMAASAGL 485
Cdd:PRK09579 403 IVVVENIHRHIEegKSPF------DAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIV 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 486 AITLVPVLMGYFIRgkvvsEKKNP------LNRLLIAI---YMPVLKQVMKFPKLTIVAAVLVtiVGFWPVDKI--GSEF 554
Cdd:PRK09579 477 ALTLSPMMCALLLR-----HEENPsglahrLDRLFERLkqrYQRALHGTLNTRPVVLVFAVIV--LALIPVLLKftQSEL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 555 IPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAETATDpapltmIETFIqLKPREEwREGVT 634
Cdd:PRK09579 550 APEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQSG------IGGFL-LKPWNE-RERTQ 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 635 TESLKAEFDKLVKFPGL-TNAWVMPiktriDMLATGIKTPVGIKVAGP-ELDVIQDIGQQIEQLLPEVTGTASVYSERVA 712
Cdd:PRK09579 622 MELLPLVQAKLEEIPGLqIFGFNLP-----SLPGTGEGLPFQFVINTAnDYESLLQVAQRVKQRAQESGKFAFLDIDLAF 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 713 GGRYIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQ-TIEGQErYPVNLRYPQDYRDSPEQLARLPVVTPSGQRIAL 791
Cdd:PRK09579 697 DKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRfTIDGRS-YKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPL 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 792 GDVADIRVENGPPGIKS----ENARINGWTFIDIDSVdVGTYVENAKEHlannltLPAGYSITWAGQYEYMERAKEKLTY 867
Cdd:PRK09579 776 STLITLSDRARPRQLNQfqqlNSAIISGFPIVSMGEA-IETVQQIAREE------APEGFAFDYAGASRQYVQEGSALWV 848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 868 VLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQAlae 947
Cdd:PRK09579 849 TFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQL--- 925
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 948 LKEKAVERAELISDdayqdallhGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVLLTLIVLP 1027
Cdd:PRK09579 926 RHEQGLSRREAIEE---------AAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLP 996
|
1050
....*....|
gi 940688358 1028 AIYSIIKKPE 1037
Cdd:PRK09579 997 CIYTLLAKPD 1006
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
1-1037 |
0e+00 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 1496.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 1 MIESIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQ 80
Cdd:COG3696 1 MLNRIIRFSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 81 TVRGYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQLGPDATGVGWVYIYALTDKSGNHDLSQLRSIQ 160
Cdd:COG3696 81 EVRSISRFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPELGPISTGLGEIYQYTLESDPGKYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 161 DWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSV 240
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 241 SDIEKIPLGiNEQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVVMRFGENAQQTINGVKEKLESLKSSLPEGVE 320
Cdd:COG3696 241 EDIENIVVK-TRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 321 VVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAI 400
Cdd:COG3696 320 IVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 401 GAMTDGAIVMIENMHKHMEKTP--LTDENRWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLAYTKTYA 478
Cdd:COG3696 400 GIIVDGAVVMVENILRRLEENRaaGTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 479 MAASAGLAITLVPVLMGYFIRGKVvSEKKNPLNRLLIAIYMPVLKQVMKFPKLTIVAAVLVTIVGFWPVDKIGSEFIPPL 558
Cdd:COG3696 480 LLGALLLSLTLVPVLASLLLRGKV-PEKENPLVRWLKRLYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGSEFLPEL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 559 DEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAETATDPAPLTMIETFIQLKPREEWREGVTTESL 638
Cdd:COG3696 559 DEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAEDATDPMGVNMSETFVILKPRSEWRSGRTKEEL 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 639 KAEFD-KLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQDIGQQIEQLLPEVTGTASVYSERVAGGRYI 717
Cdd:COG3696 639 IAEMReALEQIPGVNFNFSQPIQMRVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQL 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 718 KVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQLARLPVVTPSGQRIALGDVADI 797
Cdd:COG3696 719 DIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADI 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 798 RVENGPPGIKSENARINGWTFIDIDSVDVGTYVENAKEHLANNLTLPAGYSITWAGQYEYMERAKEKLTYVLPLTLAIIV 877
Cdd:COG3696 799 EVVEGPNQISRENGRRRIVVQANVRGRDLGSFVAEAQAKVAEQVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIF 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 878 ILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQALAelkekavERAE 957
Cdd:COG3696 879 LLLYLAFGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRA-------EGLD 951
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 958 LisddayQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVLLTLIVLPAIYSIIKKPE 1037
Cdd:COG3696 952 L------REAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGGLITSTLLTLLVLPALYLLFGRRR 1025
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
1-1033 |
0e+00 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 1165.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 1 MIESIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQ 80
Cdd:TIGR00914 1 MIERIISFSVAQRWLVLLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 81 TVRGYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQLGPDATGVGWVYIYALTDKSGN-------HDL 153
Cdd:TIGR00914 81 TTRSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEMGPISTGLGEIFLYTVEAEEGArkkdggaYTL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 154 SQLRSIQDWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTA 233
Cdd:TIGR00914 161 TDLRTIQDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 234 TGYIQSVSDIEKIPLGiNEQGTPLRIGDVANVNLGPQMRRGIAELNgEGEVVGGVVVMRFGENAQQTINGVKEKLESLKS 313
Cdd:TIGR00914 241 PGQVQSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATEN-GKEVVLGTVFMLIGENSRTVAQAVGDKLETINK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 314 SLPEGVEVVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSL 393
Cdd:TIGR00914 319 TLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 394 GgiAIAIGAMTDGAIVMIENMHKHMEK------TPLTDENRWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRM 467
Cdd:TIGR00914 399 G--ALDFGLIVDGAVVIVENAHRRLAEaqhhhgRQLTLKERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKM 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 468 FSPLAYTKTYAMAASAGLAITLVPVLMGYFIRGKvVSEKKNPLNRLLIAIYMPVLKQVMKFPKLTIVAAVLVTIVGFWPV 547
Cdd:TIGR00914 477 FHPMAFTVVLALAGAMILSLTFVPAAVALFIRGK-VAEKENRLMRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIA 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 548 DKIGSEFIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAETATDPAPLTMIETFIQLKPRE 627
Cdd:TIGR00914 556 SRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPMPPNASDTYIILKPES 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 628 EWREGVTT--ESLKAEFDKLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQDIGQQIEQLLPEVTGTAS 705
Cdd:TIGR00914 636 QWPEGKKTkeDLIEEIQEATVRIPGNNYEFTQPIQMRFNELISGVRSDVAVKVFGDDLDDLDATAEKISAVLKGVPGAAD 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 706 VYSERVAGGRYIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQLARLPVVTPS 785
Cdd:TIGR00914 716 VKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPL 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 786 G-----QRIALGDVADIRVENGPPGIKSENARINGWTFIDIDSVDVGTYVENAKEHLANNLTLPAGYSITWAGQYEYMER 860
Cdd:TIGR00914 796 SedarkQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVRGRDLGSFVDDAKKAIAEQVKLPPGYWITWGGQFEQLQS 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 861 AKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVY 940
Cdd:TIGR00914 876 ATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISF 955
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 941 LNQALAELKekaveraelisddAYQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVL 1020
Cdd:TIGR00914 956 IRKLLEEGP-------------SLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATL 1022
|
1050
....*....|...
gi 940688358 1021 LTLIVLPAIYSII 1033
Cdd:TIGR00914 1023 LTLFVLPALYRLV 1035
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
5-1034 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 706.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 5 IIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRG 84
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 85 YSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ-LGPDATGVGWVYIYALTDKSGNHDLSQLRSIQDWF 163
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPgISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADTN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 164 LKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSVSDI 243
Cdd:pfam00873 161 IKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 244 EKIPLGiNEQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGVEVVP 323
Cdd:pfam00873 241 EKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQ-KLPGANAIETADAVRAKLAELKPTFPQGVEIVV 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 324 VYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAM 403
Cdd:pfam00873 319 VYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLV 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 404 TDGAIVMIENMHKHMEKTPLTdeNRwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLAYTKTYAMAASA 483
Cdd:pfam00873 399 VDDAIVVVENIERVLEENGLK--PL-EAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 484 GLAITLVPVLMGYFIRGKVVSEKK------NPLNRLLIAIYMPVLKQVMKFPKLTIVAAVLVTIVGFWPVDKIGSEFIPP 557
Cdd:pfam00873 476 LVALTLTPALCATLLKPRREPKHGgffrwfNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPE 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 558 LDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAEtATDPAPLTMIETFIQLKPREEWREGVTT-- 635
Cdd:pfam00873 556 EDEGVFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAF-SGDNNGPNSGDAFISLKPWKERPGPEKSvq 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 636 ESLKAEFDKLVKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVAGPELDVIQDIGQQIEQLLPEVTGTASVYSERVAGGR 715
Cdd:pfam00873 635 ALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQP 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 716 YIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQLARLPVVTPSGQRIALGDVA 795
Cdd:pfam00873 715 QLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFA 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 796 DIRVENGPPGIKsenaRINGWTFIDIDSV----DVGTYVENAKEHLANNLTLPAGYSITWAGQYEYMERAKEKLTYVLPL 871
Cdd:pfam00873 795 KIEWGYGPPSIN----RYNGFRSIVISGNvaagDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIAL 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 872 TLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQALAELKEK 951
Cdd:pfam00873 871 ALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKS 950
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 952 AVEraelisddayqdALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVLLTLIVLPAIYS 1031
Cdd:pfam00873 951 LEE------------AILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYV 1018
|
...
gi 940688358 1032 IIK 1034
Cdd:pfam00873 1019 LFH 1021
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
4-1035 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 661.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 4 SIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVR 83
Cdd:COG0841 2 NLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYIT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 84 GYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ----LGPDATGVGWVyiyALTdkSGNHDLSQLRSI 159
Cdd:COG0841 82 STSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPgvtkVNPSDFPVMVL---ALS--SDDLDELELSDY 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 160 QDWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQS 239
Cdd:COG0841 157 AERNIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 240 VSDIEKIPLGINeQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGV 319
Cdd:COG0841 237 PEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQ-KQPGANALEVADAVRAKLEELQASLPEGV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 320 EVVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIA 399
Cdd:COG0841 315 ELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLA 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 400 IGAMTDGAIVMIENMHKHMEKtpltDENRWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLAYTKTYAM 479
Cdd:COG0841 395 IGIVVDDAIVVVENIERHMEE----GLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIAL 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 480 AASAGLAITLVPVLMGYFIRGKVVSEKK---NPLNRL---LIAIYMPVLKQVMKFPKLTIVAAVLVTIVGFWPVDKIGSE 553
Cdd:COG0841 471 LISLFVALTLTPALCARLLKPHPKGKKGrffRAFNRGfdrLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTE 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 554 FIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAETATDPaplTMIETFIQLKPREEwREgV 633
Cdd:COG0841 551 FFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGS---NSGTIFVTLKPWDE-RD-R 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 634 TTESLKAE-FDKLVKFPGLTnawVMPIKTRIDMLATGikTPVGIKVAGPELDVIQDIGQQIEQLLPEVTGTASVYSERVA 712
Cdd:COG0841 626 SADEIIARlREKLAKIPGAR---VFVFQPPAGGLGSG--APIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQL 700
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 713 GGRYIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQLARLPVVTPSGQRIALG 792
Cdd:COG0841 701 GKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLS 780
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 793 DVADIRVENGPPGIKsenaRINGWTFIDI-----DSVDVGTyVENAKEHLANNLTLPAGYSITWAGQYEYMERAKEKLTY 867
Cdd:COG0841 781 SVATIEEGTGPSSIN----RYNGQRSVTVsanlaPGVSLGE-ALAAIEELAAELKLPPGVSIEFTGQAEEEQESFSSLGL 855
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 868 VLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQALAE 947
Cdd:COG0841 856 AFLLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREE 935
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 948 LKEKaveraelisddayQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVLLTLIVLP 1027
Cdd:COG0841 936 GMSL-------------REAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVP 1002
|
....*...
gi 940688358 1028 AIYSIIKK 1035
Cdd:COG0841 1003 VLYVLLDR 1010
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
17-1035 |
4.35e-126 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 409.41 E-value: 4.35e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 17 LLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYSFFGDSYVYII 96
Cdd:NF033617 12 LLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQSSLGYSTITLQ 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 97 FDDDTDLYWARSRVLEYLSQVASSLPDSAKP-----QLGPDATGVgwVYIyALTdkSGNHDLSQLRSIQDWFLKYELQTV 171
Cdd:NF033617 92 FRLGTDLDVALSEVQAAINAAQSLLPSEAPDppvyrKANSADTPI--MYI-GLT--SEEMPRGQLTDYAERVLAPKLSQI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 172 PGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATGYIQSVSDIEKIPLGIN 251
Cdd:NF033617 167 NGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYEDLVIKYA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 252 EQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVVMRfGENAQQTINGVKEKLESLKSSLPEGVEVVPVYDRSKLI 331
Cdd:NF033617 247 DNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQP-GANPIEVADEIRALLPELQETLPKNIKVNVLYDRTRFI 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 332 DRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGAIVMI 411
Cdd:NF033617 326 RASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDDAIVVV 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 412 ENMHKHME--KTPLtdenrwQIVAKAASEVG-PALFFSLLIITVsFLPVFILEAQEGRMFSPLAYTKTYAMAASAGLAIT 488
Cdd:NF033617 406 ENIHRHIEegESPL------EAALKGAREIGfTVIAMTLTLVAV-YLPILFMGGLTGRLFREFAVTLAGAVIISGIVALT 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 489 LVPVLMGYFIRGkvvSEKKNPLNRL-------LIAIYMPVLKQVMKFPKLTIVAAVLVTIVGFWPVDKIGSEFIPPLDEG 561
Cdd:NF033617 479 LTPMMCSRLLKA---NEKPGRFARAvdrffdgLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRG 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 562 DLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAETATDPAPLtmieTFIQLKPREEwREGVTTESLKAE 641
Cdd:NF033617 556 VIFGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNPGDNTGF----GIINLKPWDE-RDVSAQEIIDRL 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 642 FDKLVKFPGLtNAWVMPIKTrIDMLATGIKTPVGIKVAGPELDVIQDIGQQIEQLLPEVTGTASVYSERVAGGRYIKVDI 721
Cdd:NF033617 631 RPKLAKVPGM-DLFLFPLQD-LPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDI 708
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 722 SRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQLARLPVVTPSGQRIALGDVADIRVEN 801
Cdd:NF033617 709 DRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERA 788
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 802 GPPGIkSENARINGWT--FIDIDSVDVGTYVEnAKEHLANNLtLPAGYSITWAGQYEYMERAKEKLTYVLPLTLAIIVIL 879
Cdd:NF033617 789 APLSL-NHFNQFNSATlsFNLAPGVSLGEAIE-ALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLV 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 880 LYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQAlaeLKEKAVERaeli 959
Cdd:NF033617 866 LAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANEL---QRHQGLSR---- 938
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 940688358 960 sddayQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVLLTLIVLPAIYSIIKK 1035
Cdd:NF033617 939 -----REAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
15-1035 |
4.89e-82 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 288.94 E-value: 4.89e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 15 FVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYS-FFGDSYV 93
Cdd:TIGR00915 11 FAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSdSDGSMTI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 94 YIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ-LGPDATGVGWVYIYALTDKSGNHDLSQLRSIQDWFLKYELQTVP 172
Cdd:TIGR00915 91 TLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQgVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAASNMVDPLSRLE 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 173 GVSEVAAVGgmvKQY--QVQVDPDKLRAYDIPLSLIQIALQKGNKETGAS------VVEMAEAEYMVTATGYIQSVSDIE 244
Cdd:TIGR00915 171 GVGDVQLFG---SQYamRIWLDPAKLNSYQLTPADVISAISAQNAQISAGqlgglpAVPGQQLNATIIAQTRLQTPEQFE 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 245 KIPLGINEQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGVEVVPV 324
Cdd:TIGR00915 248 NILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIK-LATGANALDTAKAVKAELAVLEPFFPQGMKYVYP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 325 YDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMT 404
Cdd:TIGR00915 327 YDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAIGLLV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 405 DGAIVMIENMHKHMEKTPLTDENRWQivaKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLAYTKTYAMAASAG 484
Cdd:TIGR00915 407 DDAIVVVENVERVMAEEGLPPKEATR---KSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVL 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 485 LAITLVPVL---MGYFIRGKVVSEKK----NPLNRLLIAI---YMPVLKQVMKFPKLTIVAAVLVTIVGFWPVDKIGSEF 554
Cdd:TIGR00915 484 VALILTPALcatMLKPIEKGEHHEKKggffGWFNRMFDSSthgYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPTSF 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 555 IPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVP--EVENVFGKVGRAETATDPaplTMIETFIQLKPREEwREG 632
Cdd:TIGR00915 564 LPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEkaNVESVFTVNGFSFAGRGQ---NMGMAFIRLKDWEE-RTG 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 633 VTTESLKAEFDKLVKFPGLTNAWVMPIktrIDMLATGIKTPVGIKV-----AGPELDVIQDIGQQIEQLLPEVTGTASVY 707
Cdd:TIGR00915 640 KENSVFAIAGRATGHFMQIKDAMVIAF---VPPAILELGNATGFDFflqdrAGLGHEALLQARNQLLGLAAQNPALTRVR 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 708 SERVAGGRYIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQLARLPVVTPSGQ 787
Cdd:TIGR00915 717 PNGLEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGE 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 788 RIALGDVADIRVENGPPGIKsenaRINGWTFIDIDS-----VDVGTYVEnAKEHLANNltLPAGYSITWAGQyEYMERAK 862
Cdd:TIGR00915 797 MVPFSAFATVRWEYGSPQLE----RYNGLPSMEILGsaapgVSTGQAMA-AMEAIAQK--LPPGFGFSWTGM-SYEERLS 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 863 EKLTYVL-PLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGvIMLVYL 941
Cdd:TIGR00915 869 GSQAPALyALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNA-ILIVEF 947
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 942 NQALAELKEKAVEraelisddayqdALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVLL 1021
Cdd:TIGR00915 948 AKELMAQGKSIVE------------AALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVL 1015
|
1050
....*....|....
gi 940688358 1022 TLIVLPAIYSIIKK 1035
Cdd:TIGR00915 1016 AIFFVPLFYVVVRR 1029
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
17-1037 |
5.18e-69 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 250.52 E-value: 5.18e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 17 LLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYSF--FGDSYVY 94
Cdd:PRK09579 15 SVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRqnFSIISIY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 95 IIFDDDTDLYWarSRVLEYLSQVASSLP-DSAKPQLGPDAT-GVGWVYIYALTDKSGNHDLSQL--RSIQDwflkyELQT 170
Cdd:PRK09579 95 ARIGADSDRLF--TELLAKANEVKNQLPqDAEDPVLSKEAAdASALMYISFYSEEMSNPQITDYlsRVIQP-----KLAT 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 171 VPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEmaeAEYMVT---ATGYIQSVSDIEKIP 247
Cdd:PRK09579 168 LPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVK---GEYVVTsinASTELKSAEAFAAIP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 248 LGINEQgTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVVMRfGENAQQTINGVKEKLESLKSSLPEGVEVVPVYDR 327
Cdd:PRK09579 245 VKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATP-SANPLDVIKEVRAIMPELESQLPPNLKVSIAYDA 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 328 SKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGA 407
Cdd:PRK09579 323 TLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVVDDA 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 408 IVMIENMHKHME--KTPLtdenrwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLAYTKTYAMAASAGL 485
Cdd:PRK09579 403 IVVVENIHRHIEegKSPF------DAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIV 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 486 AITLVPVLMGYFIRgkvvsEKKNP------LNRLLIAI---YMPVLKQVMKFPKLTIVAAVLVtiVGFWPVDKI--GSEF 554
Cdd:PRK09579 477 ALTLSPMMCALLLR-----HEENPsglahrLDRLFERLkqrYQRALHGTLNTRPVVLVFAVIV--LALIPVLLKftQSEL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 555 IPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAETATDpapltmIETFIqLKPREEwREGVT 634
Cdd:PRK09579 550 APEEDQGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQSG------IGGFL-LKPWNE-RERTQ 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 635 TESLKAEFDKLVKFPGL-TNAWVMPiktriDMLATGIKTPVGIKVAGP-ELDVIQDIGQQIEQLLPEVTGTASVYSERVA 712
Cdd:PRK09579 622 MELLPLVQAKLEEIPGLqIFGFNLP-----SLPGTGEGLPFQFVINTAnDYESLLQVAQRVKQRAQESGKFAFLDIDLAF 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 713 GGRYIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQ-TIEGQErYPVNLRYPQDYRDSPEQLARLPVVTPSGQRIAL 791
Cdd:PRK09579 697 DKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRfTIDGRS-YKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPL 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 792 GDVADIRVENGPPGIKS----ENARINGWTFIDIDSVdVGTYVENAKEHlannltLPAGYSITWAGQYEYMERAKEKLTY 867
Cdd:PRK09579 776 STLITLSDRARPRQLNQfqqlNSAIISGFPIVSMGEA-IETVQQIAREE------APEGFAFDYAGASRQYVQEGSALWV 848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 868 VLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQAlae 947
Cdd:PRK09579 849 TFGLALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQL--- 925
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 948 LKEKAVERAELISDdayqdallhGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGGMTSAVLLTLIVLP 1027
Cdd:PRK09579 926 RHEQGLSRREAIEE---------AAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLP 996
|
1050
....*....|
gi 940688358 1028 AIYSIIKKPE 1037
Cdd:PRK09579 997 CIYTLLAKPD 1006
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
13-1030 |
7.36e-65 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 238.09 E-value: 7.36e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 13 RFFVL---------LITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVR 83
Cdd:PRK10614 2 KFFALfiyrpvatiLLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 84 GYSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDS---------AKPQLGPdatgvgwvyIYALTDKSGNHDLS 154
Cdd:PRK10614 82 SSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGmpsrptyrkANPSDAP---------IMILTLTSDTYSQG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 155 QLRSIQDWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTAT 234
Cdd:PRK10614 153 QLYDFASTQLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTN 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 235 GYIQSVSDIEKIPLGINeQGTPLRIGDVANVNLGPQMRRGiAELNGEGEVVGGVVVMRFGENAQQTINGVKEKLESLKSS 314
Cdd:PRK10614 233 DELKTAAEYQPLIIHYN-NGAAVRLGDVATVTDSVQDVRN-AGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRET 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 315 LPEGVEVVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLG 394
Cdd:PRK10614 311 IPAAIDLQIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLM 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 395 GIAIAIGAMTDGAIVMIENMHKHMEK--TPLtdenrwQIVAKAASEVGpalfFSLLIITVS----FLPVFILEAQEGRMF 468
Cdd:PRK10614 391 ALTIATGFVVDDAIVVLENISRHLEAgmKPL------QAALQGVREVG----FTVLSMSLSlvavFLPLLLMGGLPGRLF 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 469 SPLAYTKTYAMAASAGLAITLVPVLMGYFIRGKVVSEKKNP--LNRLLIAI---YMPVLKQVMKFPKLtiVAAVLVTIVG 543
Cdd:PRK10614 461 REFAVTLSVAIGISLLVSLTLTPMMCAWLLKSSKPREQKRLrgFGRMLVALqqgYGRSLKWVLNHTRW--VGVVLLGTIA 538
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 544 F--WPVDKIGSEFIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAETATDpapltmiETFI 621
Cdd:PRK10614 539 LnvWLYISIPKTFFPEQDTGRLMGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSG-------MMFI 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 622 QLKPREEWREgvTTESLKAEF-DKLVKFPGlTNAWVMPIKtriDMLATGIKTPVGIKVA--GPELDVIQDIGQQIEQLLP 698
Cdd:PRK10614 612 TLKPLSERSE--TAQQVIDRLrVKLAKEPG-ANLFLMAVQ---DIRVGGRQSNASYQYTllSDDLAALREWEPKIRKALA 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 699 EVTGTASVYSERVAGGRYIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQLAR 778
Cdd:PRK10614 686 ALPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEK 765
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 779 LPVVTPSGQRIALGDVADIRVENGPPGIKSENarINGWTFIDIDSVDVGTYVE--NAKEHLANNLTLPAGYSITWAGQYE 856
Cdd:PRK10614 766 MFVINNEGKAIPLSYFAKWQPANAPLSVNHQG--LSAASTISFNLPTGKSLSDasAAIERAMTQLGVPSTVRGSFAGTAQ 843
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 857 YMERAKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGlwLMYLEGFN--FSVAVGVGFIALAGVAVEIG 934
Cdd:PRK10614 844 VFQETMNSQLILILAAIATVYIVLGILYESYVHPLTILSTLPSAGVGA--LLALELFNapFSLIALIGIMLLIGIVKKNA 921
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 935 VIMLVYLNQAlaelkekavERAELISDdayQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVGG 1014
Cdd:PRK10614 922 IMMVDFALEA---------QRNGNLTA---QEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGG 989
|
1050
....*....|....*.
gi 940688358 1015 MTSAVLLTLIVLPAIY 1030
Cdd:PRK10614 990 LVMSQLLTLYTTPVVY 1005
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
7-1033 |
4.12e-62 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 230.12 E-value: 4.12e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 7 RWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYS 86
Cdd:PRK09577 3 RFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 87 FFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKP---QLGPDATGVGwvYIYALTDKSGNHDLSQLRSIQDWF 163
Cdd:PRK09577 83 SAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRdgiQVEKAADNIQ--LIVSLTSDDGRLTGVELGEYASAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 164 LKYELQTVPGVSEVAAVGGmvkQYQVQV--DPDKLRAYDIPLSLIQIALQKGNK-----ETGASVV-EMAEAEYMVTATG 235
Cdd:PRK09577 161 VLQALRRVEGVGKVQFWGA---EYAMRIwpDPVKLAALGLTASDIASAVRAHNArvtigDIGRSAVpDSAPIAATVFADA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 236 YIQSVSDIEKIPLGINEQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSL 315
Cdd:PRK09577 238 PLKTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIK-LAPGSNAVATEKRVRATMDELSRYF 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 316 PEGVEVVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGG 395
Cdd:PRK09577 317 PPGVKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 396 IAIAIGAMTDGAIVMIENMHKHMEKTPLTDenrWQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLAYTK 475
Cdd:PRK09577 397 MVLAIGILVDDAIVVVENVERLMVEEGLSP---YDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSL 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 476 TYAMAASAGLAITLVPVLMGYFIRgKVVSEKKNP------LNRLLIAI---YMPVLKQVMKFPKLTIVAAVLVTIVGFWP 546
Cdd:PRK09577 474 AVSIGFSAFLALSLTPALCATLLK-PVDGDHHEKrgffgwFNRFVARStqrYATRVGAILKRPLRWLVVYGALTAAAALL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 547 VDKIGSEFIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGRAETATDPAPLTMIETFIQLKPR 626
Cdd:PRK09577 553 FTRLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGEGPNGGMIFVTLKDWKER 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 627 EEWREGVtteslKAEFDKL-VKFPGLTNAWVMpiktridmlatGIKTPvgikvAGPELDV-------IQDIG-------- 690
Cdd:PRK09577 633 KAARDHV-----QAIVARInERFAGTPNTTVF-----------AMNSP-----ALPDLGStsgfdfrLQDRGglgyaafv 691
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 691 QQIEQLLPEVTGTASVYSERVAG---GRYIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQ 767
Cdd:PRK09577 692 AAREQLLAEGAKDPALTDLMFAGtqdAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADG 771
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 768 DYRDSPEQLARLPVVTPSGQRIALGDVADIRVENGPPGIksenARINGWTFIDIDSVDVGTYVEN----AKEHLANnlTL 843
Cdd:PRK09577 772 RHRLDPDDVKKLRVRNAQGEMVPLAAFATLHWTLGPPQL----TRYNGYPSFTINGSAAPGHSSGeamaAIERIAA--TL 845
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 844 PAGYSITWAGQyEYMERAKEKLTyvlPLTLAIIVILLYLNFRAFSE-----VAIIIVtLPMAMIGGLWLMYLEGFNFSVA 918
Cdd:PRK09577 846 PAGIGYAWSGQ-SFEERLSGAQA---PMLFALSVLVVFLALAALYEswsipFAVMLV-VPLGVIGAVLGVTLRGMPNDIY 920
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 919 VGVGFIALAGVAVEiGVIMLVYLnqalaeLKEKAVERAELIsddayqDALLHGAGLRVRPVMMTVATIIIGLMPILYGTG 998
Cdd:PRK09577 921 FKVGLIATIGLSAK-NAILIVEV------AKDLVAQRMSLA------DAALEAARLRLRPIVMTSLAFGVGVLPLAFASG 987
|
1050 1060 1070
....*....|....*....|....*....|....*
gi 940688358 999 TGSEVMSRIAAPMVGGMTSAVLLTLIVLPAIYSII 1033
Cdd:PRK09577 988 AASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVV 1022
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
15-1049 |
1.42e-57 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 216.31 E-value: 1.42e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 15 FVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYS-FFGDSYV 93
Cdd:PRK15127 11 FAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdSTGTVQI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 94 YIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ-LGPDATGVGWVYIYALTDKSGNHDLSQLRSIQDWFLKYELQTVP 172
Cdd:PRK15127 91 TLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQgVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDPISRTS 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 173 GVSEVAAVGGmvkQYQVQV--DPDKLRAYDI-PLSLIQiALQKGNKET------GASVVEMAEAEYMVTATGYIQSVSDI 243
Cdd:PRK15127 171 GVGDVQLFGS---QYAMRIwmNPNELNKFQLtPVDVIN-AIKAQNAQVaagqlgGTPPVKGQQLNASIIAQTRLTSTEEF 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 244 EKIPLGINEQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGVEVVP 323
Cdd:PRK15127 247 GKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIK-LATGANALDTAAAIRAELAKMEPFFPSGLKIVY 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 324 VYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAM 403
Cdd:PRK15127 326 PYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLL 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 404 TDGAIVMIENMHKHMEKTPLTDEnrwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLAYTKTYAMAASA 483
Cdd:PRK15127 406 VDDAIVVVENVERVMAEEGLPPK---EATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 484 GLAITLVPVLMGYFIR-------GKVVSEKKNPLNRLL---IAIYMPVLKQVMKFPKLTIVAAVLVTIVGFWPVDKIGSE 553
Cdd:PRK15127 483 LVALILTPALCATMLKpiakgdhGEGKKGFFGWFNRMFeksTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLPSS 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 554 FIPPLDEGDLMYMPTTYPGISIGKARELLQQ-TDK-LIRTVPEVENV-----FGKVGRAETatdpaplTMIeTFIQLKPr 626
Cdd:PRK15127 563 FLPDEDQGVFLTMVQLPAGATQERTQKVLNEvTDYyLTKEKNNVESVfavngFGFAGRGQN-------TGI-AFVSLKD- 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 627 eeWREGVTTESlkaefdklvKFPGLTNAWVMPIKTRIDMLATGIKTPVGIKVA---GPELDVIQDIG---QQIEQLLPEV 700
Cdd:PRK15127 634 --WADRPGEEN---------KVEAITMRATRAFSQIKDAMVFAFNLPAIVELGtatGFDFELIDQAGlghEKLTQARNQL 702
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 701 TGTASVYSERVAGGR--------YIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDS 772
Cdd:PRK15127 703 LGEAAKHPDMLVGVRpngledtpQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRML 782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 773 PEQLARLPVVTPSGQRIALGDVADIRVENGPPGIKsenaRINGWTFIDIdsvdVGTYVENAKEHLANNL------TLPAG 846
Cdd:PRK15127 783 PDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLE----RYNGLPSMEI----LGQAAPGKSTGEAMELmeelasKLPTG 854
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 847 YSITWAGQyEYMERAKEKLTyvlPLTLAIIVILLYLNFRAFSEVAII----IVTLPMAMIGGLWLMYLEGFNFSVAVGVG 922
Cdd:PRK15127 855 VGYDWTGM-SYQERLSGNQA---PALYAISLIVVFLCLAALYESWSIpfsvMLVVPLGVIGALLAATFRGLTNDVYFQVG 930
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 923 FIALAGVAVEiGVIMLVYLNQALAELKEKAveraeLIsddayqDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSE 1002
Cdd:PRK15127 931 LLTTIGLSAK-NAILIVEFAKDLMDKEGKG-----LI------EATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSG 998
|
1050 1060 1070 1080
....*....|....*....|....*....|....*....|....*..
gi 940688358 1003 VMSRIAAPMVGGMTSAVLLTLIVLPAIYSIIKKpevnAFNKELSNVE 1049
Cdd:PRK15127 999 AQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRR----RFSRKNEDIE 1041
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
13-1030 |
1.40e-51 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 197.65 E-value: 1.40e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 13 RFFVL------LITLIIAFGGLYSLQKTPVDALP--DLSDVQVIikTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRG 84
Cdd:PRK10503 14 RLFILrpvattLLMVAILLAGIIGYRALPVSALPevDYPTIQVV--TLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 85 YSFFGDSYVYIIFDDDTDLYWARSRVLEYLSQVASSLPD---------SAKPQLGPdatgvgwvyIYALTDKSGNHDLSQ 155
Cdd:PRK10503 92 QSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSdlpnppvysKVNPADPP---------IMTLAVTSTAMPMTQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 156 LRSIQDWFLKYELQTVPGVSEVAAVGGMVKQYQVQVDPDKLRAYDIPLSLIQIALQKGNKETGASVVEMAEAEYMVTATG 235
Cdd:PRK10503 163 VEDMVETRVAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSAND 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 236 YIQSVSDIEKIPLGInEQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVVMRfGENAQQTINGVKEKLESLKSSL 315
Cdd:PRK10503 243 QMQSAEEYRQLIIAY-QNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQP-GANIIATADSIRQMLPQLTESL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 316 PEGVEVVPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGG 395
Cdd:PRK10503 321 PKSVKVTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMA 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 396 IAIAIGAMTDGAIVMIENMHKHMEKtpltDENRWQIVAKAASEVG---PALFFSLLIItvsFLPVFILEAQEGRMFSPLA 472
Cdd:PRK10503 401 LTIATGFVVDDAIVVIENISRYIEK----GEKPLAAALKGAGEIGftiISLTFSLIAV---LIPLLFMGDIVGRLFREFA 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 473 YTKTYAMAASAGLAITLVPVLMGYFIRGKVVSeKKNPLNRL-------LIAIYMPVLKQVMKFPKLTIVAAV--LVTIVG 543
Cdd:PRK10503 474 VTLAVAILISAVVSLTLTPMMCARMLSQESLR-KQNRFSRAsermfdrVIAAYGRGLAKVLNHPWLTLSVALstLLLTVL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 544 FWPVdkIGSEFIPPLDEGDLMYMPTTYPGISIGKARELLQQTDKLIRTVPEVENVFGKVGraETATDPApLTMIETFIQL 623
Cdd:PRK10503 553 LWIF--IPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVG--VDGTNPS-LNSARLQINL 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 624 KPREEWREGVTT--ESLKAefdKLVKFPGLTnAWVMPIKT-RIDMLATgiKTPVGIKVAGPELDVIQDIGQQIEQLLPEV 700
Cdd:PRK10503 628 KPLDERDDRVQKviARLQT---AVAKVPGVD-LYLQPTQDlTIDTQVS--RTQYQFTLQATSLDALSTWVPKLMEKLQQL 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 701 TGTASVYSERVAGG--RYIKVDisRDKSSRFGLNIEDVQQVVSTAIgGMNVTQTIEGQ-ERYPVNLRYPQDYRDSPEQLA 777
Cdd:PRK10503 702 PQLSDVSSDWQDKGlvAYVNVD--RDSASRLGISMADVDNALYNAF-GQRLISTIYTQaNQYRVVLEHNTENTPGLAALD 778
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 778 RLPVVTPSGQRIALGDVADIRVENGPPGIKS-ENARINGWTFIDIDSVDVGTYVeNAKEHLANNLTLPAGYSITWAGQYE 856
Cdd:PRK10503 779 TIRLTSSDGGVVPLSSIATIEQRFGPLSINHlDQFPSTTISFNVPDGYSLGDAV-QAIMDTEKTLNLPADITTQFQGSTL 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 857 YMERAkekLTYVLPLTLAIIV---ILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVaVEI 933
Cdd:PRK10503 858 AFQSA---LGSTVWLIVAAVVamyIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGI-VKK 933
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 934 GVIMLVylNQALAELKEKAVERAELIsddaYQDALlhgagLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAAPMVG 1013
Cdd:PRK10503 934 NAIMMI--DFALAAEREQGMSPRDAI----YQACL-----LRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVG 1002
|
1050
....*....|....*..
gi 940688358 1014 GMTSAVLLTLIVLPAIY 1030
Cdd:PRK10503 1003 GLIVSQVLTLFTTPVIY 1019
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
15-1035 |
8.27e-51 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 195.05 E-value: 8.27e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 15 FVLLITLIIAFGGLYSLQKTPVDALPDLSDVQVIIKTSYPGQAPQVVQDQVTFPLTTAMLSVPGAQTVRGYSF-FGDSYV 93
Cdd:PRK10555 11 FAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSgTGQASV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 94 YIIFDDDTDLYWARSRVLEYLSQVASSLPDSAKPQ-LGPDATGVGWVYIYALTDKSGNHDLsqlRSIQDWF---LKYELQ 169
Cdd:PRK10555 91 TLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQgVTVRKTGDTNILTIAFVSTDGSMDK---QDIADYVasnIQDPLS 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 170 TVPGVSEVAAVGgmvKQYQVQV--DPDKLRAYDIPLSLIQIALQKGNKET------GASVVEMAEAEYMVTATGYIQSVS 241
Cdd:PRK10555 168 RVNGVGDIDAYG---SQYSMRIwlDPAKLNSFQMTTKDVTDAIESQNAQIavgqlgGTPSVDKQALNATINAQSLLQTPE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 242 DIEKIPLGINEQGTPLRIGDVANVNLGPQMRRGIAELNGEGEVVGGVVvMRFGENAQQTINGVKEKLESLKSSLPEGVEV 321
Cdd:PRK10555 245 QFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVK-LASGANEMATAKLVLNRLDELAQYFPHGLEY 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 322 VPVYDRSKLIDRAVDNLWSKLLEELAVVAIVCVAFLFHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIG 401
Cdd:PRK10555 324 KVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIG 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 402 AMTDGAIVMIENMHKHMEKTPLTDEnrwQIVAKAASEVGPALFFSLLIITVSFLPVFILEAQEGRMFSPLAYTKTYAMAA 481
Cdd:PRK10555 404 LLVDDAIVVVENVERIMSEEGLTPR---EATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 482 SAGLAITLVPVLMGYFIR----GKVVSEK------KNPLNRLLIAIYMPVLKQVMKFPKLTIVAAVLVTIVGFWPVdKIG 551
Cdd:PRK10555 481 SVLVAMILTPALCATLLKplkkGEHHGQKgffgwfNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFL-RLP 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 552 SEFIPPLDEGDLMYMPTTYPGISigkarelLQQTDKLIRTVPE---------VENVFGKVGRAETATDPAPLTMietFIQ 622
Cdd:PRK10555 560 TSFLPLEDRGMFTTSVQLPSGST-------QQQTLKVVEKVEKyyfthekdnVMSVFATVGSGPGGNGQNVARM---FIR 629
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 623 LKPREEwREGVTTESLkAEFDKLVK-FPGLTNAWVMPIKTRIdmlATGIKTPVGIKV-----AGPELDVIQDIGQQIEQL 696
Cdd:PRK10555 630 LKDWDE-RDSKTGTSF-AIIERATKaFNKIKEARVIASSPPA---ISGLGSSAGFDMelqdhAGAGHDALMAARNQLLAL 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 697 LPEVTGTASVYSERVAGGRYIKVDISRDKSSRFGLNIEDVQQVVSTAIGGMNVTQTIEGQERYPVNLRYPQDYRDSPEQL 776
Cdd:PRK10555 705 AAKNPELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDI 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 777 ARLPVVTPSGQRIALGDVADIRVENGPPGIKsenaRINGWTFIDI-----DSVDVGTYVeNAKEHLANNltLPAGYSITW 851
Cdd:PRK10555 785 NLWYVRNKDGGMVPFSAFATSRWETGSPRLE----RYNGYSAVEIvgeaaPGVSTGTAM-DIMESLVKQ--LPNGFGLEW 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 852 AGQyEYMER---AKEKLTYVlpLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAG 928
Cdd:PRK10555 858 TAM-SYQERlsgAQAPALYA--ISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIG 934
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 929 VAVEIGVIMLVYLNqalaELKEKAverAELISddayqdALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIA 1008
Cdd:PRK10555 935 LSAKNAILIVEFAN----EMNQKG---HDLFE------ATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVG 1001
|
1050 1060
....*....|....*....|....*..
gi 940688358 1009 APMVGGMTSAVLLTLIVLPAIYSIIKK 1035
Cdd:PRK10555 1002 TGVMGGMISATILAIFFVPLFFVLVRR 1028
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
3-412 |
2.82e-13 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 74.37 E-value: 2.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 3 ESIIRWSIGNRFFVLLITLIIAFGGLYSLQKTPVDALP--DLSDVQVIIKTsyPGQAPQVVQDQVTFPLTTAMLSVPGAQ 80
Cdd:COG0841 516 GRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPeeDQGQIIVSVQL--PPGTSLERTEAVVRQVEEILLEVPEVE 593
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 81 TVrgYSFFGDSY---------VYIIFDDDTDlywaRSR----VLEYLSQVASSLPD----SAKPQLGPDATGVGwvYIYA 143
Cdd:COG0841 594 SV--FSVVGFSGggsgsnsgtIFVTLKPWDE----RDRsadeIIARLREKLAKIPGarvfVFQPPAGGLGSGAP--IEVQ 665
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 144 LTDKsgnhDLSQLRSIQDWFLKyELQTVPGVSEVAAVGGMVK-QYQVQVDPDKLRAYDIPLSLIQIALQkgNKETGASVV 222
Cdd:COG0841 666 LQGD----DLEELAAAAEKLLA-ALRQIPGLVDVRSDLQLGKpELQLDIDREKAAALGVTVADVASTLR--AALGGRYVN 738
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 223 EMAEAE-----YMVTATGYIQSVSDIEKIPLgINEQGTPLRIGDVANVnlgpQMRRGIAELNgegevvggvvvmRFGENA 297
Cdd:COG0841 739 DFNRGGreydvRVQAPEEDRNSPEDLENLYV-RTPDGEMVPLSSVATI----EEGTGPSSIN------------RYNGQR 801
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 298 QQTING--------------VKEKLESLKssLPEGVEVVPVYDrSKLIDRAVDNLWSKLLeeLAVVAI-VCVAFLF-HLR 361
Cdd:COG0841 802 SVTVSAnlapgvslgealaaIEELAAELK--LPPGVSIEFTGQ-AEEEQESFSSLGLAFL--LALLLVyLVLAAQFeSFI 876
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 940688358 362 SSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGAIVMIE 412
Cdd:COG0841 877 QPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVD 927
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
854-1036 |
6.80e-12 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 69.89 E-value: 6.80e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 854 QYEYMERAKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAVGVGFIALAGVAVEI 933
Cdd:COG1033 209 RGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDY 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 934 GVIMLVYLNQALAEL--KEKAVERAelisddayqdalLHGAGlrvRPVMMTVATIIIGLMPILYgtgTGSEVMSRIAAPM 1011
Cdd:COG1033 289 GIHLLNRYREERRKGldKREALREA------------LRKLG---PPVLLTSLTTAIGFLSLLF---SDIPPIRDFGIVA 350
|
170 180
....*....|....*....|....*
gi 940688358 1012 VGGMTSAVLLTLIVLPAIYSIIKKP 1036
Cdd:COG1033 351 AIGVLLAFLTSLTLLPALLSLLPRP 375
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
346-1035 |
7.09e-12 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 69.50 E-value: 7.09e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 346 LAVVAIVCVAFLF--HLRSSIVAVVTLPLGILVSFIIMYMQGINANIMS--LGGIAIAIGamTDGAIVMIENMHKHMEKT 421
Cdd:COG1033 226 LALLLILLLLFLFfrSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTilVPPLLLAIG--IDYGIHLLNRYREERRKG 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 422 pltdENRWQIVAKAASEVGPALFFSLLIITVSFLpVFileaqegrMFSPLAYTKTYAMAASAG------LAITLVPVLMG 495
Cdd:COG1033 304 ----LDKREALREALRKLGPPVLLTSLTTAIGFL-SL--------LFSDIPPIRDFGIVAAIGvllaflTSLTLLPALLS 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 496 YF---IRGKVVSEKKNPLNRLLIAIympvLKQVMKFPKLTIVAAVLVTIVGFWPVDKIGSEFIPPldegdlmympttypg 572
Cdd:COG1033 371 LLprpKPKTRRLKKPPELGRLLAKL----ARFVLRRPKVILVVALVLAVVSLYGISRLKVEYDFE--------------- 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 573 isigkarELLQQTDKLIRTVPEVENVFGKVGraetatdpaPLTMIetfiqlkpreewregvtteslkaefdklvkfpglt 652
Cdd:COG1033 432 -------DYLPEDSPIRQDLDFIEENFGGSD---------PLEVV----------------------------------- 460
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 653 nawvmpiktridmlatgIKTPVGIKVAGPE-LDVIQDIGQQIEQLlPEVTGTASVYServaggryikvdisrdkssrfgl 731
Cdd:COG1033 461 -----------------VDTGEPDGLKDPEvLKEIDRLQDYLESL-PEVGKVLSLAD----------------------- 499
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 732 niedvqqVVSTAIGGMNvtqtiegqERYPVNLRYPqdyrDSPEQLARLPVVTPSGQRIALGDVADIrvengppgiKSENA 811
Cdd:COG1033 500 -------LVKELNQALN--------EGDPKYYALP----ESRELLAQLLLLLSSPPGDDLSRFVDE---------DYSAA 551
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 812 RINGWTfIDIDSVDVGTYVENAKEHLANNLtLPAGYSITWAGQ----YEYMERAKEKLTYVLPLTLAIIVILLYLNFRAF 887
Cdd:COG1033 552 RVTVRL-KDLDSEEIKALVEEVRAFLAENF-PPDGVEVTLTGSavlfAAINESVIESQIRSLLLALLLIFLLLLLAFRSL 629
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 888 SEVAIIIVTLPMAMIGGLWLMYL--EGFNFSVAVgVGFIALaGVAVEIGVIMLVYLNQALAELK--EKAVERAelisdda 963
Cdd:COG1033 630 RLGLISLIPNLLPILLTFGLMGLlgIPLNIATAV-VASIAL-GIGVDYTIHFLSRYREERRKGGdlEEAIRRA------- 700
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 940688358 964 yqdalLHGAGlrvRPVMMTVATIIIGlmpilYGTGTGSE--VMSRIAAPMVGGMTSAVLLTLIVLPAIYSIIKK 1035
Cdd:COG1033 701 -----LRTTG---KAILFTSLTLAAG-----FGVLLFSSfpPLADFGLLLALGLLVALLAALLLLPALLLLLDP 761
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
291-494 |
2.91e-09 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 61.03 E-value: 2.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 291 MRFGENAQQTINGVKEKLESL--KSSLPEGVEV-----VPVYdrSKLIDRAVDNLWSKLLeeLAVVAI-VCVAFLFH-LR 361
Cdd:COG1033 555 VRLKDLDSEEIKALVEEVRAFlaENFPPDGVEVtltgsAVLF--AAINESVIESQIRSLL--LALLLIfLLLLLAFRsLR 630
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 362 SSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGAIVMIENMHKHMEKtpltDENRWQIVAKAASEVGP 441
Cdd:COG1033 631 LGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRK----GGDLEEAIRRALRTTGK 706
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 940688358 442 ALFFSLLIITVSFLpVFileaqegrMFSPLAYTKTYAMAASAGL------AITLVPVLM 494
Cdd:COG1033 707 AILFTSLTLAAGFG-VL--------LFSSFPPLADFGLLLALGLlvallaALLLLPALL 756
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
855-1036 |
2.13e-08 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 58.47 E-value: 2.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 855 YEYMERAKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMI--GGLWLMYLEGFNF-SVAVGVGFIalaGVAV 931
Cdd:TIGR03480 261 DEELATVSEGATVAGLLSFVLVLVLLWLALRSPRLVFAVLVTLIVGLIltAAFATLAVGHLNLiSVAFAVLFI---GLGV 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 932 EIGVIMLVYLnqalaelkekaveRAELISDDAYQDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGTGSEVMSRIAApm 1011
Cdd:TIGR03480 338 DFAIQFSLRY-------------REERFRGGNHREALSVAARRMGAALLLAALATAAGFFAFLPTDYKGVSELGIIAG-- 402
|
170 180
....*....|....*....|....*
gi 940688358 1012 vGGMTSAVLLTLIVLPAIYSIIKKP 1036
Cdd:TIGR03480 403 -TGMFIALFVTLTVLPALLRLLRPP 426
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
364-547 |
6.36e-07 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 53.62 E-value: 6.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 364 IVAVVTLPLGILVSFIIMYMQGINA---NIMSLGGIAIAIgamtDGAIVMI----ENMHKHmektpltdENRWQIVAKAA 436
Cdd:COG2409 201 LTAGLAVGVALGLLALLAAFTDVSSfapNLLTMLGLGVGI----DYALFLVsryrEELRAG--------EDREEAVARAV 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 437 SEVGPALFFSLLIITVSFLpvfileaqeGRMFSPLAYTKTYAMAASAG------LAITLVPVLMGYFirGKVVSEKKNPL 510
Cdd:COG2409 269 ATAGRAVLFSGLTVAIALL---------GLLLAGLPFLRSMGPAAAIGvavavlAALTLLPALLALL--GRRVFWPRRPR 337
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 940688358 511 NRLLIA----IYMPVLKQVMKFPKLTIVAAVLVTIVGFWPV 547
Cdd:COG2409 338 RRRAAApesgFWRRLARAVVRRPVPVLVAAVAVLLALALPA 378
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
772-1040 |
7.62e-07 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 53.30 E-value: 7.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 772 SPEQLARLPVVTPSGQRIALGDVAdiRVENGPPGIKSENArINGW--TFIDIDSVDVGTYVENAKE----------HLAN 839
Cdd:PRK09579 236 SAEAFAAIPVKTSGDSRVLLGDVA--RVEMGAENYDSISS-FDGIpsVYIGIKATPSANPLDVIKEvraimpelesQLPP 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 840 NLTLPAGYSITwagqyEYMERAKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAV 919
Cdd:PRK09579 313 NLKVSIAYDAT-----LFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLT 387
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 920 GVGFIALAGVAVEIGVIMLVYLNQALAELKEKAveraelisddayqDALLHGAGLRVRPVMMTVATIIIGLMPILYGTGT 999
Cdd:PRK09579 388 LLAMVLAIGLVVDDAIVVVENIHRHIEEGKSPF-------------DAALEGAREIAMPVVSMTITLAAVYAPIGFLTGL 454
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 940688358 1000 GSEVMSRIAAPMVGGMTSAVLLTLIVLPAIYSIIKKPEVNA 1040
Cdd:PRK09579 455 TGALFKEFALTLAGAVIISGIVALTLSPMMCALLLRHEENP 495
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
695-1036 |
8.95e-06 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 50.11 E-value: 8.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 695 QLLPEVTGTASVYSERVAGGRY-IKVDISRDKSSRFGLNIEDVQ--------QVVSTAIGGM------NVTQTIEGQERy 759
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYaMRIWLDPAKLNSYQLTPADVIsaisaqnaQISAGQLGGLpavpgqQLNATIIAQTR- 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 760 pvnLRYPQDYRDSpeqlarLPVVTPSGQRIALGDVAdiRVENGPPGIKSeNARING--------WTFIDIDSVDVGTYVE 831
Cdd:TIGR00915 240 ---LQTPEQFENI------LLKVNTDGSQVRLKDVA--RVELGGENYSI-SARFNGkpasglaiKLATGANALDTAKAVK 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 832 NAKEHLANNLtlPAGYSITWAgqYEYMERAKEKL-----TYVLPLTLAIIVILLYL-NFRAfseVAIIIVTLPMAMIGGL 905
Cdd:TIGR00915 308 AELAVLEPFF--PQGMKYVYP--YDTTPFVEASIeevvhTLIEAIVLVFLVMYLFLqNFRA---TLIPTIAVPVVLLGTF 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 906 WLMYLEGFNFSVAVGVGFIALAGVAVEIGVIMLVYLNQALAELKEKAVEraelisddAYQDAL--LHGAGLRVRPVMMTV 983
Cdd:TIGR00915 381 AVLAAFGFSINTLTMFAMVLAIGLLVDDAIVVVENVERVMAEEGLPPKE--------ATRKSMgqIQGALVGIAMVLSAV 452
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 940688358 984 atiiigLMPILYGTGTGSEVMSRIAAPMVGGMTSAVLLTLIVLPAIYSIIKKP 1036
Cdd:TIGR00915 453 ------FVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKP 499
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
844-1029 |
9.86e-06 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 49.84 E-value: 9.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 844 PAGYSITWAG----QYEYMERAKEKLTYVLPLTLAIIVILLYLNFRAFSEVAIIIVTLPMAMIGGLWLMYLEGFNFSVAV 919
Cdd:TIGR00921 170 PSGKFLDVTGspaiNYDIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATT 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 920 GVGFIALAGVAVEIGVIMlvyLNQALAELKE-KAVERAELISddayqdalLHGAGlrvRPVMMTVATIIIGLMPILYgtg 998
Cdd:TIGR00921 250 LLAVPMLIGVGIDYGIQT---LNRYEEERDIgRAKGEAIVTA--------VRRTG---RAVLIALLTTSAGFAALAL--- 312
|
170 180 190
....*....|....*....|....*....|.
gi 940688358 999 TGSEVMSRIAAPMVGGMTSAVLLTLIVLPAI 1029
Cdd:TIGR00921 313 SEFPMVSEFGLGLVAGLITAYLLTLLVLPAL 343
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
346-556 |
1.04e-04 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 46.37 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 346 LAVVAIVCVAFLF----HLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGAIVMIENMHKHMEKT 421
Cdd:TIGR00921 199 MAISGILVVLVLLldfkRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGVGIDYGIQTLNRYEEERDIG 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 422 PLTDEnrwqIVAKAASEVGPALFFSLLIITVSFLPVFIleaQEGRMFSPLAYTKTYAMAASAGLAITLVPVLMGYFIRGK 501
Cdd:TIGR00921 279 RAKGE----AIVTAVRRTGRAVLIALLTTSAGFAALAL---SEFPMVSEFGLGLVAGLITAYLLTLLVLPALLQSIDIGR 351
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 940688358 502 VVSEKKNPLNRLLIAIYMPVLKQVMKFPK----LTIVAAVLVTIVGFWPVDKIGSE-----FIP 556
Cdd:TIGR00921 352 EKVKKEIIAIGGKSSEIEEELSKVLSITVrhpvPALVAALIITGLGLYGAAGIKPEvniekFIP 415
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
340-496 |
4.54e-03 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 40.98 E-value: 4.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 940688358 340 SKLLEELAVVAIVCVAFLfHLRSSIVAVVTLPLGILVSFIIMYMQGINANIMSLGGIAIAIGAMTDGAIVMienMHKHME 419
Cdd:TIGR00921 572 MTIAGAILVLMILLAVFR-NPIKAVFPLIAIGSGILWAIGLMGLRGIPSFLAMATTISIILGLGMDYSIHL---AERYFE 647
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 940688358 420 KtpLTDENRWQIVAKAASEVGPALFFSLLIITVSFLPVfileaqegrMFSPLAYTKTYAMAASAGLAITLVPVLMGY 496
Cdd:TIGR00921 648 E--RKEHGPKEAITHTMERTGPGILFSGLTTAGGFLSL---------LLSHFPIMRNFGLVQGIGVLSSLTAALVVF 713
|
|
| |
